Homo sapiens

9 known processes

ICOS

inducible T-cell co-stimulator

(Aliases: CVID1,AILIM,MGC39850,CD278)

ICOS biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
positive regulation of immune system process GO:0002684 283 0.316
cell activation GO:0001775 213 0.300
leukocyte activation GO:0045321 164 0.289
immune response GO:0006955 307 0.226
positive regulation of immune response GO:0050778 159 0.217
immune system development GO:0002520 195 0.205
hematopoietic or lymphoid organ development GO:0048534 186 0.194
cytokine production GO:0001816 247 0.190
t cell activation GO:0042110 99 0.181
lymphocyte activation GO:0046649 133 0.181
positive regulation of cell activation GO:0050867 81 0.175
regulation of leukocyte activation GO:0002694 115 0.155
hemopoiesis GO:0030097 180 0.153
regulation of immune response GO:0050776 201 0.148
positive regulation of cell proliferation GO:0008284 301 0.147
response to cytokine GO:0034097 232 0.139
defense response GO:0006952 315 0.130
regulation of cytokine production GO:0001817 232 0.126
positive regulation of transport GO:0051050 336 0.092
regulation of defense response GO:0031347 154 0.091
amine metabolic process GO:0009308 44 0.090
cellular ketone metabolic process GO:0042180 80 0.087
immune response activating cell surface receptor signaling pathway GO:0002429 45 0.083
positive regulation of lymphocyte activation GO:0051251 73 0.083
activation of immune response GO:0002253 114 0.083
regulation of cellular ketone metabolic process GO:0010565 50 0.082
positive regulation of cytokine production GO:0001819 167 0.081
positive regulation of leukocyte activation GO:0002696 80 0.079
leukocyte differentiation GO:0002521 98 0.078
immune response activating signal transduction GO:0002757 90 0.077
positive regulation of cell death GO:0010942 263 0.076
ras protein signal transduction GO:0007265 73 0.075
lymphocyte proliferation GO:0046651 70 0.075
mononuclear cell proliferation GO:0032943 71 0.074
g protein coupled receptor signaling pathway GO:0007186 207 0.073
negative regulation of t cell cytokine production GO:0002725 4 0.071
response to other organism GO:0051707 261 0.071
regulation of cell differentiation GO:0045595 393 0.070
regulation of cell activation GO:0050865 125 0.068
innate immune response GO:0045087 178 0.066
regulation of cellular amine metabolic process GO:0033238 11 0.066
positive regulation of t cell activation GO:0050870 54 0.065
regulation of establishment of protein localization GO:0070201 242 0.064
cellular response to cytokine stimulus GO:0071345 181 0.063
response to oxygen containing compound GO:1901700 369 0.062
cytoplasmic transport GO:0016482 379 0.061
positive regulation of lymphocyte proliferation GO:0050671 46 0.061
cytokine mediated signaling pathway GO:0019221 109 0.060
response to biotic stimulus GO:0009607 276 0.060
regulation of lymphocyte activation GO:0051249 103 0.060
positive regulation of hydrolase activity GO:0051345 331 0.060
negative regulation of cell proliferation GO:0008285 228 0.059
secretion by cell GO:0032940 226 0.059
cellular amino acid metabolic process GO:0006520 116 0.059
eosinophil mediated immunity GO:0002447 2 0.058
positive regulation of cellular component organization GO:0051130 376 0.058
regulation of protein transport GO:0051223 213 0.058
regulation of response to external stimulus GO:0032101 222 0.057
cellular amine metabolic process GO:0044106 41 0.056
positive regulation of t cell proliferation GO:0042102 33 0.056
positive regulation of leukocyte proliferation GO:0070665 48 0.056
regulation of t cell activation GO:0050863 77 0.055
regulation of immune effector process GO:0002697 91 0.055
positive regulation of apoptotic process GO:0043065 246 0.055
regulation of mononuclear cell proliferation GO:0032944 65 0.055
cell type specific apoptotic process GO:0097285 125 0.055
small gtpase mediated signal transduction GO:0007264 78 0.055
regulation of cellular component movement GO:0051270 334 0.055
post embryonic development GO:0009791 2 0.054
positive regulation of cellular amine metabolic process GO:0033240 7 0.054
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.051
actin filament based process GO:0030029 224 0.051
rho protein signal transduction GO:0007266 26 0.049
response to external biotic stimulus GO:0043207 261 0.049
cell adhesion GO:0007155 325 0.049
secretion GO:0046903 254 0.049
biological adhesion GO:0022610 331 0.048
signal transduction by phosphorylation GO:0023014 297 0.047
regulation of cellular amino acid metabolic process GO:0006521 6 0.047
leukocyte proliferation GO:0070661 74 0.047
regulation of intracellular transport GO:0032386 195 0.047
vesicle mediated transport GO:0016192 371 0.047
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.046
establishment of protein localization to organelle GO:0072594 172 0.046
protein localization to organelle GO:0033365 280 0.046
viral life cycle GO:0019058 132 0.045
negative regulation of programmed cell death GO:0043069 321 0.044
positive regulation of protein transport GO:0051222 135 0.044
regulation of lymphocyte proliferation GO:0050670 64 0.043
positive regulation of mononuclear cell proliferation GO:0032946 47 0.043
immune response regulating signaling pathway GO:0002764 97 0.043
positive regulation of phosphorylation GO:0042327 394 0.043
regulation of leukocyte mediated immunity GO:0002703 38 0.043
myeloid cell differentiation GO:0030099 117 0.043
regulation of cell migration GO:0030334 289 0.042
lymphocyte mediated immunity GO:0002449 48 0.042
positive regulation of programmed cell death GO:0043068 249 0.042
positive regulation of locomotion GO:0040017 186 0.042
sequestering of calcium ion GO:0051208 17 0.042
cd8 positive alpha beta t cell activation GO:0036037 3 0.042
response to lipid GO:0033993 206 0.041
lipid metabolic process GO:0006629 381 0.041
immune effector process GO:0002252 159 0.041
regulation of leukocyte proliferation GO:0070663 67 0.041
response to wounding GO:0009611 168 0.041
regulation of protein localization GO:0032880 296 0.040
regulation of secretion by cell GO:1903530 177 0.040
peptidyl tyrosine modification GO:0018212 170 0.040
regulation of secretion GO:0051046 194 0.039
glycosyl compound catabolic process GO:1901658 413 0.039
nucleoside catabolic process GO:0009164 408 0.039
myeloid dendritic cell chemotaxis GO:0002408 3 0.039
negative regulation of developmental process GO:0051093 247 0.039
response to virus GO:0009615 126 0.039
lymphocyte differentiation GO:0030098 35 0.038
regulation of cell motility GO:2000145 299 0.038
nucleoside triphosphate metabolic process GO:0009141 422 0.038
regulation of astrocyte chemotaxis GO:2000458 1 0.038
ribonucleoside triphosphate metabolic process GO:0009199 412 0.038
immune response regulating cell surface receptor signaling pathway GO:0002768 51 0.038
purine nucleoside catabolic process GO:0006152 398 0.038
negative regulation of immune system process GO:0002683 136 0.038
peptidyl tyrosine phosphorylation GO:0018108 170 0.038
negative regulation of catalytic activity GO:0043086 335 0.038
positive regulation of cellular catabolic process GO:0031331 284 0.037
cation transport GO:0006812 331 0.037
eosinophil activation involved in immune response GO:0002278 2 0.037
regulation of cell cycle GO:0051726 393 0.037
nucleocytoplasmic transport GO:0006913 176 0.037
regulation of multi organism process GO:0043900 157 0.037
organophosphate catabolic process GO:0046434 430 0.037
purine nucleoside triphosphate catabolic process GO:0009146 392 0.036
single organism cellular localization GO:1902580 332 0.036
eosinophil degranulation GO:0043308 2 0.036
mapk cascade GO:0000165 288 0.035
viral process GO:0016032 146 0.035
purine nucleoside triphosphate metabolic process GO:0009144 412 0.035
determination of adult lifespan GO:0008340 2 0.035
purine containing compound catabolic process GO:0072523 411 0.035
positive regulation of gtp catabolic process GO:0033126 166 0.035
positive regulation of organelle organization GO:0010638 195 0.034
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.034
negative regulation of multicellular organismal process GO:0051241 317 0.034
nucleoside triphosphate catabolic process GO:0009143 394 0.034
interspecies interaction between organisms GO:0044419 156 0.034
i kappab kinase nf kappab signaling GO:0007249 166 0.034
regulation of cytoplasmic transport GO:1903649 149 0.034
positive regulation of innate immune response GO:0045089 79 0.034
regulation of cell adhesion GO:0030155 166 0.034
t cell differentiation in thymus GO:0033077 4 0.034
regulation of cd8 positive alpha beta t cell activation GO:2001185 2 0.033
regulation of mapk cascade GO:0043408 262 0.033
positive regulation of nucleotide metabolic process GO:0045981 230 0.033
multicellular organismal aging GO:0010259 3 0.033
regulation of hormone levels GO:0010817 125 0.033
nucleoside phosphate catabolic process GO:1901292 412 0.033
protein import GO:0017038 130 0.033
negative regulation of protein metabolic process GO:0051248 391 0.033
ribonucleoside triphosphate catabolic process GO:0009203 391 0.033
positive regulation of erk1 and erk2 cascade GO:0070374 75 0.033
positive regulation of catabolic process GO:0009896 310 0.032
purine ribonucleoside catabolic process GO:0046130 398 0.032
single organism cell adhesion GO:0098602 179 0.032
nucleotide catabolic process GO:0009166 408 0.032
carbohydrate derivative biosynthetic process GO:1901137 207 0.032
ribonucleotide catabolic process GO:0009261 405 0.031
regulation of cellular component biogenesis GO:0044087 281 0.031
cellular response to lipid GO:0071396 127 0.031
maintenance of location GO:0051235 112 0.031
sequestering of metal ion GO:0051238 24 0.031
purine ribonucleoside metabolic process GO:0046128 437 0.031
intracellular protein transport GO:0006886 270 0.031
leukocyte chemotaxis GO:0030595 76 0.031
positive regulation of cell differentiation GO:0045597 211 0.031
nuclear transport GO:0051169 179 0.030
taxis GO:0042330 157 0.030
positive regulation of secretion GO:0051047 116 0.030
positive regulation of secretion by cell GO:1903532 108 0.030
eosinophil activation GO:0043307 3 0.030
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.030
cellular lipid metabolic process GO:0044255 303 0.030
regulation of small gtpase mediated signal transduction GO:0051056 156 0.030
response to bacterium GO:0009617 144 0.030
positive regulation of peptidyl serine phosphorylation of stat protein GO:0033141 3 0.029
negative regulation of cell death GO:0060548 345 0.029
protein targeting GO:0006605 187 0.029
metal ion transport GO:0030001 272 0.029
cellular macromolecular complex assembly GO:0034622 324 0.029
positive regulation of cell motility GO:2000147 177 0.029
negative regulation of apoptotic process GO:0043066 316 0.029
regulation of response to wounding GO:1903034 101 0.029
calcium ion transport GO:0006816 147 0.028
positive regulation of lipase activity GO:0060193 28 0.028
chemical homeostasis GO:0048878 306 0.028
positive regulation of cell migration GO:0030335 172 0.028
locomotory behavior GO:0007626 1 0.028
regulation of nucleotide metabolic process GO:0006140 269 0.028
positive regulation of developmental process GO:0051094 314 0.028
regulation of myeloid cell differentiation GO:0045637 81 0.027
purine nucleotide catabolic process GO:0006195 405 0.027
regulation of purine nucleotide metabolic process GO:1900542 264 0.027
negative regulation of cellular protein metabolic process GO:0032269 353 0.027
purinergic nucleotide receptor signaling pathway GO:0035590 4 0.027
leukocyte mediated immunity GO:0002443 59 0.027
inflammatory response GO:0006954 79 0.027
regulation of cytokine secretion GO:0050707 57 0.027
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.027
t cell proliferation GO:0042098 45 0.027
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.027
purine ribonucleotide catabolic process GO:0009154 404 0.027
regulation of innate immune response GO:0045088 97 0.027
regulation of peptidase activity GO:0052547 180 0.027
positive regulation of cytoplasmic transport GO:1903651 82 0.026
negative regulation of alpha beta t cell activation GO:0046636 3 0.026
protein maturation GO:0051604 233 0.026
t cell selection GO:0045058 4 0.026
cellular homeostasis GO:0019725 196 0.026
positive regulation of leukocyte chemotaxis GO:0002690 38 0.026
positive regulation of mapk cascade GO:0043410 190 0.026
protein processing GO:0016485 226 0.026
regulation of intracellular protein transport GO:0033157 123 0.026
negative regulation of cytokine production GO:0001818 82 0.026
regulation of proteolysis GO:0030162 293 0.026
regulation of binding GO:0051098 111 0.026
t cell differentiation GO:0030217 29 0.026
reactive nitrogen species metabolic process GO:2001057 3 0.026
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 109 0.026
ribonucleoside catabolic process GO:0042454 406 0.025
regulation of calcium ion transport GO:0051924 79 0.025
actin filament organization GO:0007015 128 0.025
cytokine biosynthetic process GO:0042089 37 0.025
divalent inorganic cation transport GO:0072511 158 0.025
myeloid leukocyte activation GO:0002274 34 0.025
female gamete generation GO:0007292 2 0.025
regulation of locomotion GO:0040012 329 0.025
cell chemotaxis GO:0060326 112 0.025
guanosine containing compound catabolic process GO:1901069 239 0.024
cellular response to dna damage stimulus GO:0006974 379 0.024
regulation of cellular response to stress GO:0080135 244 0.024
protein catabolic process GO:0030163 325 0.024
positive regulation of cellular component movement GO:0051272 181 0.024
regulation of cell cycle process GO:0010564 266 0.024
stress activated protein kinase signaling cascade GO:0031098 94 0.024
mitotic cell cycle GO:0000278 326 0.024
regulation of kinase activity GO:0043549 314 0.024
apoptotic signaling pathway GO:0097190 268 0.024
reactive oxygen species biosynthetic process GO:1903409 4 0.024
cell cell signaling GO:0007267 155 0.023
negative regulation of cd4 positive alpha beta t cell proliferation GO:2000562 1 0.023
cellular protein complex assembly GO:0043623 188 0.023
cellular cation homeostasis GO:0030003 163 0.023
negative regulation of hydrolase activity GO:0051346 182 0.023
leukocyte apoptotic process GO:0071887 31 0.023
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.023
segmentation GO:0035282 4 0.023
positive regulation of cell cycle process GO:0090068 106 0.022
nitrogen compound transport GO:0071705 191 0.022
regulation of protein kinase activity GO:0045859 289 0.022
cell morphogenesis GO:0000902 296 0.022
cellular protein catabolic process GO:0044257 261 0.022
response to lipopolysaccharide GO:0032496 70 0.022
regulation of anatomical structure morphogenesis GO:0022603 286 0.022
cellular metal ion homeostasis GO:0006875 146 0.022
positive regulation of lymphocyte mediated immunity GO:0002708 23 0.022
regulation of nucleoside metabolic process GO:0009118 209 0.022
metal ion homeostasis GO:0055065 169 0.022
receptor metabolic process GO:0043112 81 0.021
cardiac muscle cell contraction GO:0086003 4 0.021
leukocyte migration GO:0050900 107 0.021
positive regulation of nucleotide catabolic process GO:0030813 185 0.021
circulatory system development GO:0072359 262 0.021
negative regulation of transport GO:0051051 176 0.021
gtp catabolic process GO:0006184 237 0.021
ion homeostasis GO:0050801 230 0.021
regulation of metal ion transport GO:0010959 120 0.021
mitotic cell cycle process GO:1903047 286 0.021
regulation of t cell proliferation GO:0042129 42 0.021
regulation of erk1 and erk2 cascade GO:0070372 99 0.021
regulation of protein secretion GO:0050708 86 0.021
regulation of epithelial cell proliferation GO:0050678 113 0.021
regulation of protein maturation GO:1903317 150 0.021
regulation of ion transport GO:0043269 189 0.021
protein import into nucleus GO:0006606 104 0.021
nervous system development GO:0007399 293 0.021
regulation of actin filament based process GO:0032970 141 0.021
regulation of vesicle mediated transport GO:0060627 130 0.021
divalent metal ion transport GO:0070838 152 0.021
cellular macromolecule catabolic process GO:0044265 380 0.020
cellular response to biotic stimulus GO:0071216 71 0.020
chemokine c c motif ligand 19 signaling pathway GO:0038115 1 0.020
cell fate determination GO:0001709 3 0.020
positive regulation of intracellular transport GO:0032388 104 0.020
positive regulation of cytokine secretion GO:0050715 42 0.020
positive regulation of nucleoside metabolic process GO:0045979 186 0.020
cellular response to oxygen containing compound GO:1901701 276 0.020
actin cytoskeleton organization GO:0030036 207 0.020
cellular response to endogenous stimulus GO:0071495 336 0.020
oogenesis GO:0048477 2 0.020
response to abiotic stimulus GO:0009628 336 0.020
erk1 and erk2 cascade GO:0070371 104 0.020
amide transport GO:0042886 76 0.020
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.020
positive regulation of response to external stimulus GO:0032103 88 0.020
regulation of cell killing GO:0031341 22 0.020
gtp metabolic process GO:0046039 239 0.020
positive regulation of i kappab kinase nf kappab signaling GO:0043123 132 0.019
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.019
regulation of peptidyl tyrosine phosphorylation GO:0050730 108 0.019
regulation of endopeptidase activity GO:0052548 170 0.019
multi organism cellular process GO:0044764 156 0.019
regulation of calcium ion transport into cytosol GO:0010522 33 0.019
phospholipid metabolic process GO:0006644 99 0.019
regulation of leukocyte migration GO:0002685 63 0.019
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.019
modification of morphology or physiology of other organism GO:0035821 43 0.019
regulation of ion homeostasis GO:2000021 73 0.019
organophosphate biosynthetic process GO:0090407 163 0.019
antigen receptor mediated signaling pathway GO:0050851 38 0.019
calcium ion transport into cytosol GO:0060402 48 0.019
negative regulation of intracellular signal transduction GO:1902532 183 0.018
regulation of viral process GO:0050792 103 0.018
regulation of nucleotide catabolic process GO:0030811 205 0.018
adaptive immune response GO:0002250 49 0.018
cd4 positive alpha beta t cell proliferation GO:0035739 2 0.018
response to organic cyclic compound GO:0014070 204 0.018
positive regulation of intracellular protein transport GO:0090316 76 0.018
cytokine secretion GO:0050663 64 0.018
chemotaxis GO:0006935 157 0.018
positive regulation of cell cycle GO:0045787 140 0.018
cellular divalent inorganic cation homeostasis GO:0072503 128 0.018
epithelial cell proliferation GO:0050673 128 0.018
regulation of lymphocyte mediated immunity GO:0002706 33 0.018
mature dendritic cell differentiation GO:0097029 2 0.018
regulation of cytoskeleton organization GO:0051493 177 0.018
protein secretion GO:0009306 98 0.018
regulation of transferase activity GO:0051338 355 0.018
guanosine containing compound metabolic process GO:1901068 244 0.018
regulation of cd4 positive alpha beta t cell proliferation GO:2000561 2 0.018
regulation of t helper 1 cell activation GO:2000517 1 0.018
stress activated mapk cascade GO:0051403 93 0.018
cell development GO:0048468 328 0.018
cellular response to lipopolysaccharide GO:0071222 57 0.018
cell division GO:0051301 168 0.018
positive regulation of cd8 positive alpha beta t cell proliferation GO:2000566 1 0.018
regulation of purine nucleotide catabolic process GO:0033121 205 0.018
cell projection organization GO:0030030 252 0.018
negative regulation of cellular component movement GO:0051271 106 0.017
lymphocyte apoptotic process GO:0070227 20 0.017
regulation of cell morphogenesis GO:0022604 153 0.017
regulation of lipid metabolic process GO:0019216 96 0.017
lipid biosynthetic process GO:0008610 177 0.017
positive regulation of immune effector process GO:0002699 40 0.017
membrane organization GO:0061024 292 0.017
regulation of homeostatic process GO:0032844 121 0.017
phagocytosis recognition GO:0006910 3 0.017
response to acid chemical GO:0001101 66 0.017
positive regulation of protein phosphorylation GO:0001934 313 0.017
glial cell migration GO:0008347 4 0.017
positive regulation of leukocyte mediated immunity GO:0002705 24 0.017
neuromuscular junction development GO:0007528 3 0.017
nuclear import GO:0051170 106 0.017
pattern recognition receptor signaling pathway GO:0002221 48 0.017
positive regulation of stress activated mapk cascade GO:0032874 60 0.017
protein localization to nucleus GO:0034504 136 0.017
negative regulation of phosphorus metabolic process GO:0010563 267 0.017
calcium ion homeostasis GO:0055074 122 0.017
response to inorganic substance GO:0010035 127 0.017
cell growth GO:0016049 160 0.016
regulation of reactive oxygen species biosynthetic process GO:1903426 3 0.016
astrocyte cell migration GO:0043615 1 0.016
organonitrogen compound biosynthetic process GO:1901566 200 0.016
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 85 0.016
positive regulation of transferase activity GO:0051347 227 0.016
negative regulation of phosphate metabolic process GO:0045936 267 0.016
cellular response to tumor necrosis factor GO:0071356 63 0.016
regulation of peptide transport GO:0090087 62 0.016
negative regulation of cell motility GO:2000146 104 0.016
response to tumor necrosis factor GO:0034612 76 0.016
leukocyte activation involved in immune response GO:0002366 30 0.016
memory GO:0007613 3 0.016
regulation of protein complex assembly GO:0043254 147 0.016
cellular component morphogenesis GO:0032989 314 0.016
regeneration GO:0031099 4 0.016
covalent chromatin modification GO:0016569 254 0.016
protein targeting to nucleus GO:0044744 104 0.016
release of cytoplasmic sequestered nf kappab GO:0008588 4 0.016
single organism membrane organization GO:0044802 268 0.016
positive regulation of defense response GO:0031349 87 0.016
establishment of t cell polarity GO:0001768 2 0.016
regulation of leukocyte chemotaxis GO:0002688 46 0.016
response to nitric oxide GO:0071731 4 0.016
regulation of chemotaxis GO:0050920 74 0.016
regulation of regulatory t cell differentiation GO:0045589 4 0.016
negative regulation of binding GO:0051100 57 0.016
positive regulation of calcium ion transport GO:0051928 51 0.016
negative regulation of cellular component organization GO:0051129 235 0.016
chemokine c c motif ligand 21 signaling pathway GO:0038116 1 0.016
camp metabolic process GO:0046058 61 0.016
positive regulation of reactive oxygen species metabolic process GO:2000379 24 0.016
negative regulation of interleukin 5 production GO:0032714 3 0.016
negative regulation of cell cycle GO:0045786 193 0.016
negative regulation of protein processing GO:0010955 142 0.015
single organism nuclear import GO:1902593 104 0.015
adult locomotory behavior GO:0008344 1 0.015
positive regulation of gtpase activity GO:0043547 166 0.015
regulation of ras gtpase activity GO:0032318 128 0.015
cellular ion homeostasis GO:0006873 168 0.015
monocarboxylic acid metabolic process GO:0032787 185 0.015
positive regulation of ras gtpase activity GO:0032320 117 0.015
epithelial cell differentiation GO:0030855 141 0.015
mature natural killer cell chemotaxis GO:0035782 1 0.015
positive regulation of homeostatic process GO:0032846 47 0.015
regulation of stress activated mapk cascade GO:0032872 84 0.015
interleukin 1 production GO:0032612 26 0.015
regulation of protein polymerization GO:0032271 63 0.015
regulation of behavior GO:0050795 82 0.015
granzyme a production GO:0035746 1 0.015
oxidation reduction process GO:0055114 396 0.015
neurogenesis GO:0022008 169 0.015
epithelium development GO:0060429 227 0.015
activation of innate immune response GO:0002218 55 0.015
cellular chemical homeostasis GO:0055082 180 0.015
regulation of leukocyte apoptotic process GO:2000106 25 0.015
hindbrain development GO:0030902 3 0.015
negative regulation of locomotion GO:0040013 118 0.015
regulation of protein processing GO:0070613 150 0.015
positive regulation of cell killing GO:0031343 19 0.015
negative regulation of cytokine production involved in immune response GO:0002719 13 0.015
positive regulation of leukocyte differentiation GO:1902107 37 0.015
spermatid differentiation GO:0048515 4 0.015
regulation of cysteine type endopeptidase activity GO:2000116 127 0.015
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.015
regulation of cell growth GO:0001558 135 0.015
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 29 0.015
chromatin modification GO:0016568 298 0.015
regulation of lipase activity GO:0060191 37 0.015
chromatin organization GO:0006325 351 0.015
regulation of cell division GO:0051302 116 0.015
defense response to other organism GO:0098542 129 0.014
steroid metabolic process GO:0008202 94 0.014
regulation of gtp catabolic process GO:0033124 180 0.014
small molecule biosynthetic process GO:0044283 157 0.014
negative regulation of leukocyte activation GO:0002695 26 0.014
regulation of body fluid levels GO:0050878 99 0.014
response to nitrogen compound GO:1901698 184 0.014
blastoderm segmentation GO:0007350 2 0.014
positive regulation of cellular component biogenesis GO:0044089 158 0.014
neurological system process GO:0050877 163 0.014
negative regulation of multi organism process GO:0043901 92 0.014
response to molecule of bacterial origin GO:0002237 82 0.014
regulation of anatomical structure size GO:0090066 101 0.014
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 43 0.014
regulation of natural killer cell mediated cytotoxicity GO:0042269 16 0.014
response to growth factor GO:0070848 205 0.014
negative regulation of cell migration GO:0030336 102 0.014
regulation of mitotic cell cycle GO:0007346 189 0.014
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.014
glycoprotein metabolic process GO:0009100 110 0.014
cellular defense response GO:0006968 2 0.014
negative regulation of immune response GO:0050777 40 0.014
regulation of ras protein signal transduction GO:0046578 155 0.014
transmembrane transport GO:0055085 399 0.014
organelle assembly GO:0070925 176 0.014
regulation of rho protein signal transduction GO:0035023 79 0.014
leukocyte mediated cytotoxicity GO:0001909 27 0.014
natural killer cell mediated immunity GO:0002228 23 0.014
blood vessel development GO:0001568 172 0.014
regulation of gtpase activity GO:0043087 180 0.014
circadian behavior GO:0048512 2 0.014
cation homeostasis GO:0055080 189 0.014
enzyme linked receptor protein signaling pathway GO:0007167 303 0.014
regulation of inflammatory response GO:0050727 46 0.014
regulation of nucleocytoplasmic transport GO:0046822 98 0.014
interferon gamma production GO:0032609 39 0.014
regulation of dna metabolic process GO:0051052 153 0.014
jnk cascade GO:0007254 80 0.014
microtubule based process GO:0007017 210 0.014
regulation of camp metabolic process GO:0030814 52 0.014
system process GO:0003008 349 0.014
negative regulation of protein maturation GO:1903318 142 0.014
divalent inorganic cation homeostasis GO:0072507 136 0.014
alcohol metabolic process GO:0006066 114 0.014
regulation of jnk cascade GO:0046328 73 0.014
positive regulation of behavior GO:0048520 60 0.014
myeloid leukocyte differentiation GO:0002573 60 0.014

ICOS disease predictions

Disease DO term ID Size Probability Func Analog Org
immune system disease DOID:2914 155 0.038
musculoskeletal system disease DOID:17 223 0.031
connective tissue disease DOID:65 109 0.029
hematopoietic system disease DOID:74 100 0.026
central nervous system disease DOID:331 186 0.017
nervous system disease DOID:863 431 0.017
cancer DOID:162 167 0.015
disease of cellular proliferation DOID:14566 174 0.015
organ system cancer DOID:0050686 164 0.015
disease of metabolism DOID:0014667 295 0.014