|
|
negative regulation of hippo signaling
|
GO:0035331 |
6 |
0.950
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.942
|
Human |
|
|
canonical wnt signaling pathway
|
GO:0060070 |
116 |
0.921
|
|
|
|
response to transforming growth factor beta
|
GO:0071559 |
94 |
0.896
|
Human |
|
|
response to growth factor
|
GO:0070848 |
205 |
0.896
|
Human |
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.857
|
|
|
|
regulation of canonical wnt signaling pathway
|
GO:0060828 |
88 |
0.780
|
|
|
|
negative regulation of wnt signaling pathway
|
GO:0030178 |
69 |
0.773
|
|
|
|
actin filament organization
|
GO:0007015 |
128 |
0.768
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.753
|
|
|
|
negative regulation of transport
|
GO:0051051 |
176 |
0.742
|
|
|
|
negative regulation of canonical wnt signaling pathway
|
GO:0090090 |
55 |
0.705
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
125 |
0.658
|
Human |
|
|
transforming growth factor beta receptor signaling pathway
|
GO:0007179 |
76 |
0.637
|
Human |
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.620
|
Human |
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.612
|
|
|
|
regulation of cell morphogenesis involved in differentiation
|
GO:0010769 |
83 |
0.609
|
|
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.597
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.575
|
Fly |
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.566
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.555
|
Human |
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.555
|
Fly |
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.541
|
Mouse |
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.537
|
|
|
|
protein ubiquitination
|
GO:0016567 |
314 |
0.514
|
|
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.508
|
|
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.494
|
Worm |
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.487
|
Worm |
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.470
|
Human |
|
|
regulation of protein complex assembly
|
GO:0043254 |
147 |
0.467
|
|
|
|
release of cytoplasmic sequestered nf kappab
|
GO:0008588 |
4 |
0.454
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
158 |
0.441
|
|
|
|
regulation of cell morphogenesis
|
GO:0022604 |
153 |
0.430
|
|
|
|
peptide transport
|
GO:0015833 |
74 |
0.413
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.407
|
|
|
|
integrin activation
|
GO:0033622 |
8 |
0.404
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
179 |
0.391
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.387
|
|
|
|
cellular response to hypoxia
|
GO:0071456 |
51 |
0.387
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.381
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.375
|
|
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.370
|
|
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
212 |
0.369
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.354
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
244 |
0.352
|
|
|
|
actin filament based process
|
GO:0030029 |
224 |
0.339
|
|
|
|
stress fiber assembly
|
GO:0043149 |
40 |
0.332
|
|
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.331
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.311
|
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
166 |
0.295
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.290
|
Mouse |
|
|
regulation of protein import into nucleus
|
GO:0042306 |
78 |
0.289
|
|
|
|
organelle fission
|
GO:0048285 |
149 |
0.283
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.275
|
Fly |
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.257
|
Human Mouse |
|
|
positive regulation of i kappab kinase nf kappab signaling
|
GO:0043123 |
132 |
0.246
|
|
|
|
negative regulation of protein transport
|
GO:0051224 |
75 |
0.246
|
|
|
|
lipid metabolic process
|
GO:0006629 |
381 |
0.245
|
|
|
|
positive regulation of nf kappab import into nucleus
|
GO:0042346 |
13 |
0.244
|
|
|
|
negative regulation of cell differentiation
|
GO:0045596 |
171 |
0.243
|
|
|
|
protein processing
|
GO:0016485 |
226 |
0.239
|
|
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.224
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.223
|
|
|
|
positive regulation of nucleocytoplasmic transport
|
GO:0046824 |
54 |
0.223
|
|
|
|
negative regulation of phagocytosis
|
GO:0050765 |
4 |
0.223
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
380 |
0.221
|
|
|
|
metal ion transport
|
GO:0030001 |
272 |
0.216
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
195 |
0.216
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.215
|
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
206 |
0.214
|
|
|
|
growth
|
GO:0040007 |
202 |
0.209
|
Fly |
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
149 |
0.209
|
|
|
|
regulation of growth
|
GO:0040008 |
165 |
0.204
|
|
|
|
regulation of cell development
|
GO:0060284 |
161 |
0.204
|
|
|
|
actin filament bundle organization
|
GO:0061572 |
54 |
0.203
|
|
|
|
gene silencing by mirna
|
GO:0035195 |
23 |
0.202
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
207 |
0.200
|
|
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.200
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
342 |
0.198
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.198
|
Mouse |
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.196
|
|
|
|
cellular response to decreased oxygen levels
|
GO:0036294 |
51 |
0.194
|
|
|
|
positive regulation of protein import into nucleus
|
GO:0042307 |
46 |
0.194
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.192
|
|
|
|
regulation of gene silencing
|
GO:0060968 |
24 |
0.187
|
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
209 |
0.186
|
|
|
|
protein targeting to nucleus
|
GO:0044744 |
104 |
0.184
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
180 |
0.184
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.184
|
|
|
|
positive regulation of locomotion
|
GO:0040017 |
186 |
0.182
|
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
123 |
0.181
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.179
|
|
|
|
maintenance of location
|
GO:0051235 |
112 |
0.174
|
|
|
|
cation transport
|
GO:0006812 |
331 |
0.174
|
|
|
|
maintenance of location in cell
|
GO:0051651 |
62 |
0.173
|
|
|
|
positive regulation of protein complex assembly
|
GO:0031334 |
86 |
0.168
|
|
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.167
|
|
|
|
ion transmembrane transport
|
GO:0034220 |
338 |
0.166
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
261 |
0.164
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
408 |
0.162
|
|
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.161
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
405 |
0.161
|
|
|
|
organelle assembly
|
GO:0070925 |
176 |
0.157
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
264 |
0.154
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
207 |
0.154
|
|
|
|
regulation of protein ubiquitination
|
GO:0031396 |
95 |
0.148
|
|
|
|
positive regulation of cytoplasmic transport
|
GO:1903651 |
82 |
0.147
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.146
|
|
|
|
inorganic ion transmembrane transport
|
GO:0098660 |
231 |
0.145
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
303 |
0.143
|
|
|
|
glycerolipid metabolic process
|
GO:0046486 |
107 |
0.141
|
|
|
|
gtp metabolic process
|
GO:0046039 |
239 |
0.138
|
|
|
|
transmembrane transport
|
GO:0055085 |
399 |
0.138
|
|
|
|
maintenance of protein location
|
GO:0045185 |
57 |
0.137
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.137
|
|
|
|
positive regulation of organ growth
|
GO:0046622 |
2 |
0.136
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.136
|
Human |
|
|
actin filament bundle assembly
|
GO:0051017 |
54 |
0.134
|
|
|
|
potassium ion transmembrane transport
|
GO:0071805 |
60 |
0.133
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.131
|
|
|
|
cell fate determination
|
GO:0001709 |
3 |
0.129
|
|
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.129
|
|
|
|
regulation of protein maturation
|
GO:1903317 |
150 |
0.128
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
405 |
0.127
|
|
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.127
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.125
|
Mouse |
|
|
protein targeting
|
GO:0006605 |
187 |
0.122
|
|
|
|
cation transmembrane transport
|
GO:0098655 |
238 |
0.121
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
404 |
0.121
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.120
|
Mouse |
|
|
cell type specific apoptotic process
|
GO:0097285 |
125 |
0.120
|
Human |
|
|
positive regulation of cell motility
|
GO:2000147 |
177 |
0.119
|
|
|
|
lung alveolus development
|
GO:0048286 |
4 |
0.119
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
140 |
0.119
|
Mouse |
|
|
biological adhesion
|
GO:0022610 |
331 |
0.117
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
394 |
0.116
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
70 |
0.116
|
|
|
|
response to decreased oxygen levels
|
GO:0036293 |
96 |
0.115
|
|
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.115
|
|
|
|
protein import into nucleus
|
GO:0006606 |
104 |
0.112
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
172 |
0.112
|
|
|
|
protein import
|
GO:0017038 |
130 |
0.110
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
191 |
0.110
|
|
|
|
cell adhesion
|
GO:0007155 |
325 |
0.108
|
|
|
|
regulation of protein targeting
|
GO:1903533 |
91 |
0.107
|
|
|
|
positive regulation of cellular component movement
|
GO:0051272 |
181 |
0.105
|
|
|
|
response to hypoxia
|
GO:0001666 |
96 |
0.105
|
|
|
|
single organismal cell cell adhesion
|
GO:0016337 |
148 |
0.104
|
|
|
|
cytoplasmic mrna processing body assembly
|
GO:0033962 |
10 |
0.104
|
|
|
|
positive regulation of monocyte chemotactic protein 1 production
|
GO:0071639 |
3 |
0.104
|
|
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
185 |
0.102
|
|
|
|
positive regulation of intracellular transport
|
GO:0032388 |
104 |
0.102
|
|
|
|
negative regulation of i kappab kinase nf kappab signaling
|
GO:0043124 |
32 |
0.102
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.100
|
|
|
|
regulation of nucleocytoplasmic transport
|
GO:0046822 |
98 |
0.100
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
408 |
0.099
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
172 |
0.099
|
|
|
|
lipid modification
|
GO:0030258 |
84 |
0.099
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.099
|
Mouse |
|
|
purine containing compound catabolic process
|
GO:0072523 |
411 |
0.098
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
398 |
0.097
|
|
|
|
regulation of gene silencing by rna
|
GO:0060966 |
6 |
0.097
|
|
|
|
neuron projection development
|
GO:0031175 |
106 |
0.096
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.096
|
|
|
|
positive regulation of protein transport
|
GO:0051222 |
135 |
0.096
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.095
|
Mouse |
|
|
potassium ion transport
|
GO:0006813 |
62 |
0.095
|
|
|
|
cell part morphogenesis
|
GO:0032990 |
137 |
0.095
|
|
|
|
nuclear division
|
GO:0000280 |
128 |
0.094
|
|
|
|
regulation of neurogenesis
|
GO:0050767 |
82 |
0.094
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
26 |
0.093
|
|
|
|
protein localization to cytoskeleton
|
GO:0044380 |
11 |
0.093
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.093
|
Mouse |
|
|
cellular potassium ion transport
|
GO:0071804 |
60 |
0.093
|
|
|
|
negative regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043154 |
46 |
0.092
|
|
|
|
cellular response to oxygen levels
|
GO:0071453 |
55 |
0.091
|
|
|
|
neuromuscular junction development
|
GO:0007528 |
3 |
0.090
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
92 |
0.090
|
|
|
|
positive regulation of protein localization to nucleus
|
GO:1900182 |
48 |
0.089
|
|
|
|
negative regulation of transferase activity
|
GO:0051348 |
124 |
0.089
|
Mouse |
|
|
mitotic nuclear division
|
GO:0007067 |
119 |
0.089
|
|
|
|
positive regulation of gtpase activity
|
GO:0043547 |
166 |
0.085
|
|
|
|
single organism carbohydrate metabolic process
|
GO:0044723 |
193 |
0.085
|
|
|
|
cardiac cell fate determination
|
GO:0060913 |
3 |
0.085
|
|
|
|
negative regulation of cysteine type endopeptidase activity
|
GO:2000117 |
48 |
0.085
|
|
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
182 |
0.084
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
156 |
0.084
|
Fly |
|
|
positive regulation of intracellular protein transport
|
GO:0090316 |
76 |
0.083
|
|
|
|
ribonucleoprotein complex biogenesis
|
GO:0022613 |
116 |
0.083
|
|
|
|
inorganic cation transmembrane transport
|
GO:0098662 |
194 |
0.083
|
|
|
|
negative regulation of proteolysis
|
GO:0045861 |
132 |
0.083
|
|
|
|
developmental growth
|
GO:0048589 |
48 |
0.083
|
|
|
|
monovalent inorganic cation transport
|
GO:0015672 |
128 |
0.082
|
|
|
|
positive regulation of transcription factor import into nucleus
|
GO:0042993 |
25 |
0.082
|
|
|
|
cellular carbohydrate metabolic process
|
GO:0044262 |
84 |
0.082
|
|
|
|
endomembrane system organization
|
GO:0010256 |
196 |
0.082
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
269 |
0.081
|
|
|
|
negative regulation of peptidase activity
|
GO:0010466 |
91 |
0.081
|
|
|
|
nuclear import
|
GO:0051170 |
106 |
0.080
|
|
|
|
endosomal transport
|
GO:0016197 |
129 |
0.080
|
|
|
|
regulation of endopeptidase activity
|
GO:0052548 |
170 |
0.079
|
|
|
|
regulation of protein processing
|
GO:0070613 |
150 |
0.079
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.076
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.076
|
|
|
|
morphogenesis of a polarized epithelium
|
GO:0001738 |
3 |
0.075
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
136 |
0.074
|
|
|
|
ribonucleoprotein complex subunit organization
|
GO:0071826 |
81 |
0.074
|
|
|
|
transcription factor import into nucleus
|
GO:0042991 |
40 |
0.074
|
|
|
|
negative regulation of protein import into nucleus
|
GO:0042308 |
30 |
0.074
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
412 |
0.073
|
|
|
|
cellular response to transforming growth factor beta stimulus
|
GO:0071560 |
94 |
0.073
|
Human |
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.073
|
|
|
|
negative regulation of endopeptidase activity
|
GO:0010951 |
84 |
0.073
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
177 |
0.072
|
|
|
|
regulation of intrinsic apoptotic signaling pathway
|
GO:2001242 |
72 |
0.072
|
|
|
|
regulation of actin filament based process
|
GO:0032970 |
141 |
0.072
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.071
|
|
|
|
regulation of binding
|
GO:0051098 |
111 |
0.071
|
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.071
|
|
|
|
regulation of ossification
|
GO:0030278 |
58 |
0.071
|
|
|
|
regulation of body fluid levels
|
GO:0050878 |
99 |
0.071
|
|
|
|
regulation of transforming growth factor beta receptor signaling pathway
|
GO:0017015 |
48 |
0.070
|
Human |
|
|
regulation of cell projection organization
|
GO:0031344 |
107 |
0.069
|
|
|
|
protein maturation
|
GO:0051604 |
233 |
0.069
|
|
|
|
regulation of nervous system development
|
GO:0051960 |
88 |
0.069
|
|
|
|
neurogenesis
|
GO:0022008 |
169 |
0.068
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.068
|
|
|
|
negative regulation of protein processing
|
GO:0010955 |
142 |
0.067
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.067
|
|
|
|
negative regulation of protein maturation
|
GO:1903318 |
142 |
0.067
|
|
|
|
establishment of planar polarity
|
GO:0001736 |
3 |
0.067
|
|
|
|
generation of neurons
|
GO:0048699 |
152 |
0.067
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.067
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
176 |
0.067
|
|
|
|
negative regulation of intracellular protein transport
|
GO:0090317 |
42 |
0.066
|
|
|
|
regulation of protein modification by small protein conjugation or removal
|
GO:1903320 |
107 |
0.066
|
|
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
85 |
0.064
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.064
|
Human |
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
239 |
0.063
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
195 |
0.063
|
|
|
|
posttranscriptional gene silencing
|
GO:0016441 |
25 |
0.062
|
|
|
|
proteasomal protein catabolic process
|
GO:0010498 |
176 |
0.062
|
|
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.062
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.061
|
|
|
|
negative regulation of nucleocytoplasmic transport
|
GO:0046823 |
37 |
0.061
|
|
|
|
response to oxygen levels
|
GO:0070482 |
100 |
0.060
|
|
|
|
negative regulation of intracellular transport
|
GO:0032387 |
60 |
0.060
|
|
|
|
mesenchyme development
|
GO:0060485 |
59 |
0.060
|
|
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
186 |
0.060
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.060
|
|
|
|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
156 |
0.060
|
|
|
|
regulation of protein localization to nucleus
|
GO:1900180 |
85 |
0.059
|
|
|
|
osteoblast differentiation
|
GO:0001649 |
92 |
0.059
|
|
|
|
regulation of osteoblast differentiation
|
GO:0045667 |
38 |
0.057
|
|
|
|
meiosis i
|
GO:0007127 |
4 |
0.057
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
227 |
0.057
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.057
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.057
|
Mouse |
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
119 |
0.057
|
Human |
|
|
negative regulation of protein serine threonine kinase activity
|
GO:0071901 |
57 |
0.057
|
Mouse |
|
|
mitochondrion distribution
|
GO:0048311 |
3 |
0.056
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.056
|
|
|
|
ribonucleoprotein complex assembly
|
GO:0022618 |
78 |
0.056
|
|
|
|
tube development
|
GO:0035295 |
125 |
0.056
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
391 |
0.055
|
|
|
|
endosome to lysosome transport
|
GO:0008333 |
21 |
0.054
|
|
|
|
maintenance of protein location in cell
|
GO:0032507 |
56 |
0.054
|
|
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043281 |
116 |
0.054
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.054
|
Mouse |
|
|
regulation of cysteine type endopeptidase activity
|
GO:2000116 |
127 |
0.053
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.053
|
Human |
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
97 |
0.053
|
|
|
|
single organism nuclear import
|
GO:1902593 |
104 |
0.052
|
|
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
166 |
0.052
|
|
|
|
negative regulation of protein localization to nucleus
|
GO:1900181 |
34 |
0.052
|
|
|
|
neuron development
|
GO:0048666 |
113 |
0.052
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.052
|
|
|
|
amide transport
|
GO:0042886 |
76 |
0.052
|
|
|
|
ossification
|
GO:0001503 |
121 |
0.052
|
|
|
|
regulation of transcription factor import into nucleus
|
GO:0042990 |
39 |
0.051
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.051
|
|
|
|
osteoblast development
|
GO:0002076 |
2 |
0.051
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.051
|
|
|
|
response to metal ion
|
GO:0010038 |
84 |
0.051
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.050
|
|
|
|
vasculature development
|
GO:0001944 |
181 |
0.050
|
Human |
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
130 |
0.050
|
|
|
|
response to hormone
|
GO:0009725 |
175 |
0.050
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
205 |
0.050
|
|
|
|
oogenesis
|
GO:0048477 |
2 |
0.050
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
230 |
0.049
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
244 |
0.049
|
|
|
|
regulation of gtpase activity
|
GO:0043087 |
180 |
0.049
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
232 |
0.049
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.048
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.048
|
Mouse |
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.048
|
|
|
|
positive regulation of immune system process
|
GO:0002684 |
283 |
0.048
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
136 |
0.047
|
|
|
|
mapk cascade
|
GO:0000165 |
288 |
0.047
|
Human Mouse |
|
|
protein localization to centrosome
|
GO:0071539 |
5 |
0.047
|
|
|
|
activation of immune response
|
GO:0002253 |
114 |
0.046
|
|
|
|
negative regulation of cytoplasmic transport
|
GO:1903650 |
46 |
0.046
|
|
|
|
response to oxidative stress
|
GO:0006979 |
121 |
0.046
|
|
|
|
regulation of peptide transport
|
GO:0090087 |
62 |
0.046
|
|
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
144 |
0.046
|
|
|
|
regulation of immune response
|
GO:0050776 |
201 |
0.045
|
|
|
|
chemical homeostasis
|
GO:0048878 |
306 |
0.045
|
|
|
|
positive regulation of camp dependent protein kinase activity
|
GO:2000481 |
4 |
0.045
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.044
|
|
|
|
morphogenesis of an epithelium
|
GO:0002009 |
60 |
0.044
|
|
|
|
aging
|
GO:0007568 |
66 |
0.044
|
Worm |
|
|
dna templated transcription initiation
|
GO:0006352 |
35 |
0.044
|
|
|
|
negative regulation of neuron apoptotic process
|
GO:0043524 |
23 |
0.044
|
|
|
|
protein localization to microtubule cytoskeleton
|
GO:0072698 |
10 |
0.044
|
|
|
|
regulation of nf kappab import into nucleus
|
GO:0042345 |
22 |
0.044
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
162 |
0.044
|
Human |
|
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
185 |
0.044
|
|
|
|
positive regulation of myeloid cell apoptotic process
|
GO:0033034 |
2 |
0.043
|
|
|
|
glycerophospholipid metabolic process
|
GO:0006650 |
84 |
0.043
|
|
|
|
mesenchymal cell development
|
GO:0014031 |
50 |
0.043
|
|
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
324 |
0.043
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.043
|
|
|
|
blood coagulation
|
GO:0007596 |
76 |
0.043
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
124 |
0.042
|
|
|
|
endocrine process
|
GO:0050886 |
25 |
0.042
|
|
|
|
immune response activating signal transduction
|
GO:0002757 |
90 |
0.042
|
|
|
|
cellular response to oxidative stress
|
GO:0034599 |
85 |
0.042
|
|
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
4 |
0.042
|
|
|
|
system process
|
GO:0003008 |
349 |
0.042
|
|
|
|
posttranscriptional gene silencing by rna
|
GO:0035194 |
25 |
0.041
|
|
|
|
actomyosin structure organization
|
GO:0031032 |
59 |
0.041
|
|
|
|
regulation of neuron death
|
GO:1901214 |
56 |
0.041
|
|
|
|
spermatid development
|
GO:0007286 |
4 |
0.040
|
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
180 |
0.040
|
|
|
|
mesenchymal cell differentiation
|
GO:0048762 |
52 |
0.040
|
|
|
|
multicellular organism reproduction
|
GO:0032504 |
42 |
0.040
|
|
|
|
gtp catabolic process
|
GO:0006184 |
237 |
0.040
|
|
|
|
regulation of metal ion transport
|
GO:0010959 |
120 |
0.039
|
|
|
|
protein autophosphorylation
|
GO:0046777 |
123 |
0.039
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
209 |
0.038
|
|
|
|
cell projection morphogenesis
|
GO:0048858 |
129 |
0.038
|
|
|
|
positive regulation of cytoskeleton organization
|
GO:0051495 |
83 |
0.038
|
|
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.038
|
Human |
|
|
epithelial to mesenchymal transition
|
GO:0001837 |
48 |
0.038
|
|
|
|
cell projection organization
|
GO:0030030 |
252 |
0.038
|
|
|
|
intracellular receptor signaling pathway
|
GO:0030522 |
104 |
0.038
|
|
|
|
actin filament based movement
|
GO:0030048 |
17 |
0.038
|
|
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.038
|
|
|
|
negative regulation of ossification
|
GO:0030279 |
21 |
0.038
|
|
|
|
gene silencing by rna
|
GO:0031047 |
26 |
0.038
|
|
|
|
cytoplasmic sequestering of protein
|
GO:0051220 |
12 |
0.038
|
|
|
|
regulation of hippo signaling
|
GO:0035330 |
8 |
0.037
|
Fly |
|
|
cell cell signaling
|
GO:0007267 |
155 |
0.037
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.037
|
|
|
|
regulation of phagocytosis engulfment
|
GO:0060099 |
2 |
0.037
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
175 |
0.037
|
|
|
|
engulfment of apoptotic cell
|
GO:0043652 |
2 |
0.037
|
|
|
|
negative regulation of cell adhesion
|
GO:0007162 |
64 |
0.037
|
|
|
|
regulation of neuron apoptotic process
|
GO:0043523 |
35 |
0.036
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.036
|
|
|
|
phosphatidylinositol metabolic process
|
GO:0046488 |
53 |
0.035
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.035
|
|
|
|
peptidyl serine phosphorylation
|
GO:0018105 |
101 |
0.035
|
Mouse |
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.035
|
|
|
|
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090100 |
41 |
0.035
|
Human |
|
|
nervous system development
|
GO:0007399 |
293 |
0.035
|
|
|
|
positive regulation of secretion by cell
|
GO:1903532 |
108 |
0.035
|
|
|
|
regulation of cell shape
|
GO:0008360 |
48 |
0.035
|
|
|
|
negative regulation of macrophage differentiation
|
GO:0045650 |
2 |
0.035
|
|
|
|
nuclear transport
|
GO:0051169 |
179 |
0.035
|
|
|
|
regulation of gene expression epigenetic
|
GO:0040029 |
73 |
0.035
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.035
|
|
|
|
alcohol metabolic process
|
GO:0006066 |
114 |
0.035
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.034
|
|
|
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
116 |
0.034
|
|
|
|
cell junction organization
|
GO:0034330 |
79 |
0.034
|
|
|
|
positive regulation of actin filament bundle assembly
|
GO:0032233 |
25 |
0.034
|
|
|
|
response to radiation
|
GO:0009314 |
151 |
0.034
|
|
|
|
organ growth
|
GO:0035265 |
12 |
0.034
|
Fly |
|
|
establishment of tissue polarity
|
GO:0007164 |
3 |
0.034
|
|
|
|
negative regulation of phagocytosis engulfment
|
GO:0060101 |
1 |
0.034
|
|
|
|
immune response
|
GO:0006955 |
307 |
0.034
|
|
|
|
positive regulation of cell morphogenesis involved in differentiation
|
GO:0010770 |
50 |
0.034
|
|
|
|
hemostasis
|
GO:0007599 |
76 |
0.034
|
|
|
|
positive regulation of gene silencing by mirna
|
GO:2000637 |
3 |
0.033
|
|
|
|
sensory organ development
|
GO:0007423 |
52 |
0.033
|
Fly |
|
|
small molecule catabolic process
|
GO:0044282 |
92 |
0.033
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
156 |
0.033
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
213 |
0.033
|
Fly |
|
|
blood vessel development
|
GO:0001568 |
172 |
0.033
|
Human |
|
|
cytokine production
|
GO:0001816 |
247 |
0.033
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
169 |
0.033
|
|
|
|
negative regulation of transcription from rna polymerase ii promoter
|
GO:0000122 |
281 |
0.033
|
|
|
|
epithelium development
|
GO:0060429 |
227 |
0.033
|
|
|
|
negative regulation of transcription factor import into nucleus
|
GO:0042992 |
17 |
0.032
|
|
|
|
regulation of response to external stimulus
|
GO:0032101 |
222 |
0.032
|
|
|
|
nf kappab import into nucleus
|
GO:0042348 |
22 |
0.032
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.032
|
Human Mouse |
|
|
response to transition metal nanoparticle
|
GO:1990267 |
29 |
0.032
|
|
|
|
golgi organization
|
GO:0007030 |
38 |
0.032
|
|
|
|
negative regulation of extrinsic apoptotic signaling pathway
|
GO:2001237 |
52 |
0.032
|
|
|
|
adherens junction organization
|
GO:0034332 |
36 |
0.032
|
|
|
|
tissue morphogenesis
|
GO:0048729 |
96 |
0.031
|
|
|
|
mitochondrion organization
|
GO:0007005 |
156 |
0.031
|
|
|
|
regulation of ubiquitin protein transferase activity
|
GO:0051438 |
28 |
0.031
|
|
|
|
regulation of myeloid cell differentiation
|
GO:0045637 |
81 |
0.031
|
|
|
|
positive regulation of cell adhesion
|
GO:0045785 |
84 |
0.030
|
|
|
|
response to wounding
|
GO:0009611 |
168 |
0.030
|
|
|
|
regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090092 |
90 |
0.030
|
Human |
|
|
photoreceptor cell differentiation
|
GO:0046530 |
2 |
0.030
|
|
|
|
positive regulation of immune response
|
GO:0050778 |
159 |
0.030
|
|
|
|
spermatid differentiation
|
GO:0048515 |
4 |
0.030
|
|
|
|
blood circulation
|
GO:0008015 |
113 |
0.030
|
|
|
|
cardiovascular system development
|
GO:0072358 |
262 |
0.030
|
Human |
|
|
renal albumin absorption
|
GO:0097018 |
1 |
0.030
|
|
|
|
secretion by cell
|
GO:0032940 |
226 |
0.030
|
|
|
|
vacuole organization
|
GO:0007033 |
44 |
0.029
|
|
|
|
memory
|
GO:0007613 |
3 |
0.029
|
|
|
|
neuron death
|
GO:0070997 |
65 |
0.029
|
|
|
|
regulation of neuron projection development
|
GO:0010975 |
57 |
0.029
|
|
|
|
regulation of ligase activity
|
GO:0051340 |
29 |
0.029
|
|
|
|
negative regulation of cell migration
|
GO:0030336 |
102 |
0.029
|
|
|
|
membrane organization
|
GO:0061024 |
292 |
0.029
|
|
|
|
atrioventricular valve development
|
GO:0003171 |
3 |
0.029
|
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.029
|
|
|
|
regulation of endocytosis
|
GO:0030100 |
72 |
0.029
|
|
|
|
negative regulation of cellular component movement
|
GO:0051271 |
106 |
0.029
|
|
|
|
regulation of i kappab kinase nf kappab signaling
|
GO:0043122 |
162 |
0.029
|
|
|
|
angiogenesis
|
GO:0001525 |
147 |
0.029
|
Human |
|
|
fatty acid metabolic process
|
GO:0006631 |
115 |
0.028
|
|
|
|
cellular cation homeostasis
|
GO:0030003 |
163 |
0.028
|
|
|
|
pituitary gland development
|
GO:0021983 |
2 |
0.028
|
|
|
|
lysosomal transport
|
GO:0007041 |
33 |
0.028
|
|
|
|
reproductive process
|
GO:0022414 |
106 |
0.028
|
|
|
|
interspecies interaction between organisms
|
GO:0044419 |
156 |
0.027
|
|
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
147 |
0.027
|
|
|
|
vacuolar transport
|
GO:0007034 |
34 |
0.027
|
|
|
|
histone modification
|
GO:0016570 |
251 |
0.027
|
|
|
|
cellular response to nitrogen compound
|
GO:1901699 |
144 |
0.027
|
|
|
|
positive regulation of neuron differentiation
|
GO:0045666 |
40 |
0.027
|
|
|
|
regeneration
|
GO:0031099 |
4 |
0.027
|
|
|
|
positive regulation of intrinsic apoptotic signaling pathway
|
GO:2001244 |
28 |
0.027
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
117 |
0.027
|
|
|
|
gene silencing
|
GO:0016458 |
49 |
0.026
|
|
|
|
epithelial cell differentiation
|
GO:0030855 |
141 |
0.026
|
|
|
|
endocytosis
|
GO:0006897 |
159 |
0.026
|
|
|
|
heart development
|
GO:0007507 |
95 |
0.026
|
|
|
|
synaptic transmission
|
GO:0007268 |
61 |
0.026
|
|
|
|
covalent chromatin modification
|
GO:0016569 |
254 |
0.026
|
|
|
|
endocardial cushion development
|
GO:0003197 |
3 |
0.026
|
|
|
|
negative regulation of blood pressure
|
GO:0045776 |
3 |
0.026
|
|
|
|
locomotory behavior
|
GO:0007626 |
1 |
0.025
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
181 |
0.025
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.025
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
193 |
0.025
|
|
|
|
response to inorganic substance
|
GO:0010035 |
127 |
0.025
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
3 |
0.025
|
|
|
|
cellular homeostasis
|
GO:0019725 |
196 |
0.025
|
|
|
|
hormone transport
|
GO:0009914 |
68 |
0.025
|
|
|
|
muscle tissue development
|
GO:0060537 |
62 |
0.025
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.025
|
Human Mouse |
|
|
protein complex localization
|
GO:0031503 |
31 |
0.025
|
|
|
|
circulatory system development
|
GO:0072359 |
262 |
0.025
|
Human |
|
|
positive regulation of endocytosis
|
GO:0045807 |
42 |
0.025
|
|
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
108 |
0.024
|
|
|
|
epithelium migration
|
GO:0090132 |
119 |
0.024
|
|
|
|
adult locomotory behavior
|
GO:0008344 |
1 |
0.024
|
|
|
|
regulation of cell matrix adhesion
|
GO:0001952 |
42 |
0.024
|
|
|
|
embryo development
|
GO:0009790 |
123 |
0.024
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.024
|
Human |
|
|
response to organic cyclic compound
|
GO:0014070 |
204 |
0.024
|
|
|
|
epithelial cell fate commitment
|
GO:0072148 |
3 |
0.024
|
|
|
|
negative regulation of endocytosis
|
GO:0045806 |
19 |
0.024
|
|
|
|
regulation of rho protein signal transduction
|
GO:0035023 |
79 |
0.024
|
|
|
|
regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903050 |
91 |
0.024
|
|
|
|
peptidyl tyrosine dephosphorylation
|
GO:0035335 |
36 |
0.024
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
170 |
0.023
|
|
|
|
muscle system process
|
GO:0003012 |
81 |
0.023
|
|
|
|
transcription initiation from rna polymerase ii promoter
|
GO:0006367 |
27 |
0.023
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
104 |
0.023
|
|
|
|
negative regulation of synaptic transmission
|
GO:0050805 |
2 |
0.023
|
|
|
|
negative regulation of protein ubiquitination
|
GO:0031397 |
35 |
0.023
|
|
|
|
wound healing
|
GO:0042060 |
115 |
0.023
|
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
146 |
0.023
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
135 |
0.023
|
|
|
|
response to nitrogen compound
|
GO:1901698 |
184 |
0.023
|
|
|
|
phospholipid metabolic process
|
GO:0006644 |
99 |
0.023
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
2 |
0.023
|
|
|
|
negative regulation of epithelial cell proliferation
|
GO:0050680 |
48 |
0.023
|
|
|
|
regulation of secretion
|
GO:0051046 |
194 |
0.023
|
|
|
|
negative regulation of neuron death
|
GO:1901215 |
32 |
0.023
|
|
|
|
negative regulation of locomotion
|
GO:0040013 |
118 |
0.022
|
|
|
|
negative regulation of cellular response to growth factor stimulus
|
GO:0090288 |
41 |
0.022
|
|
|
|
regulation of cell growth
|
GO:0001558 |
135 |
0.022
|
|
|
|
response to cytokine
|
GO:0034097 |
232 |
0.022
|
Human |
