IMP

Process View

Homo sapiens

22 genes annotated in human

regulation of nf kappab import into nucleus

Any process that modulates the frequency, rate or extent of the transfer of NF-kappaB, a transcription factor for eukaryotic RNA polymerase II promoters, from the cytoplasm into the nucleus, across the nuclear membrane.

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of nf kappab import into nucleus"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "regulation of nf kappab import into nucleus" (in gray)

Name	Description	Probability	Func Analog Organism
NFKB2	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)	0.893
IL8	interleukin 8	0.755
NFKBIA	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha	0.727
CXCL2	chemokine (C-X-C motif) ligand 2	0.445
FBXW11	F-box and WD repeat domain containing 11	0.419	Mouse Fly
TNFRSF6B	tumor necrosis factor receptor superfamily, member 6b, decoy	0.367
MYD88	myeloid differentiation primary response gene (88)	0.330
CCL4	chemokine (C-C motif) ligand 4	0.322	Human
CXCL1	chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)	0.316
CUL1	cullin 1	0.300
CCL2	chemokine (C-C motif) ligand 2	0.275	Human
CXCL3	chemokine (C-X-C motif) ligand 3	0.273
IL1R1	interleukin 1 receptor, type I	0.268
IKBKB	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta	0.245
CCR5	chemokine (C-C motif) receptor 5	0.232
SKP1	S-phase kinase-associated protein 1	0.229
RELB	v-rel reticuloendotheliosis viral oncogene homolog B	0.199
CASP8	caspase 8, apoptosis-related cysteine peptidase	0.169
RNF31	ring finger protein 31	0.167
IL1B	interleukin 1, beta	0.164
BTRC	beta-transducin repeat containing	0.148	Fly
LATS2	LATS, large tumor suppressor, homolog 2 (Drosophila)	0.143
TIRAP	toll-interleukin 1 receptor (TIR) domain containing adaptor protein	0.128
ZNF260	zinc finger protein 260	0.116
CCL8	chemokine (C-C motif) ligand 8	0.113	Human
IL6	interleukin 6 (interferon, beta 2)	0.108
CXCL9	chemokine (C-X-C motif) ligand 9	0.084
CHUK	conserved helix-loop-helix ubiquitous kinase	0.073
CCL22	chemokine (C-C motif) ligand 22	0.072	Human
ZNF420	zinc finger protein 420	0.070
ZNF84	zinc finger protein 84	0.067
CCR1	chemokine (C-C motif) receptor 1	0.066
TNF	tumor necrosis factor	0.062
RELA	v-rel reticuloendotheliosis viral oncogene homolog A (avian)	0.062
ICAM1	intercellular adhesion molecule 1	0.062
CXCL10	chemokine (C-X-C motif) ligand 10	0.061
BCL2A1	BCL2-related protein A1	0.060
CCL20	chemokine (C-C motif) ligand 20	0.059	Human
PSMD2	proteasome (prosome, macropain) 26S subunit, non-ATPase, 2	0.054
CCL5	chemokine (C-C motif) ligand 5	0.051	Human
PSMD7	proteasome (prosome, macropain) 26S subunit, non-ATPase, 7	0.051
BCL3	B-cell CLL/lymphoma 3	0.050
DPP4	dipeptidyl-peptidase 4	0.048
TNIP1	TNFAIP3 interacting protein 1	0.047
NFKB1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1	0.046
CXCL5	chemokine (C-X-C motif) ligand 5	0.045
CXCL11	chemokine (C-X-C motif) ligand 11	0.044
HIPK3	homeodomain interacting protein kinase 3	0.044
CXCL6	chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2)	0.043
ZFP30	zinc finger protein 30 homolog (mouse)	0.042
NFKBIB	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta	0.042	Human Rat
IL1R2	interleukin 1 receptor, type II	0.040
ZNF585A	zinc finger protein 585A	0.040
RANBP3	RAN binding protein 3	0.038
NFKBIE	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon	0.037	Human
ZNF571	zinc finger protein 571	0.036
BIRC3	baculoviral IAP repeat containing 3	0.035
CCL13	chemokine (C-C motif) ligand 13	0.034	Human
TNFAIP6	tumor necrosis factor, alpha-induced protein 6	0.033
ZNF567	zinc finger protein 567	0.030
IDE	insulin-degrading enzyme	0.030
PLAUR	plasminogen activator, urokinase receptor	0.029
BBS10	Bardet-Biedl syndrome 10	0.029
FAS	Fas (TNF receptor superfamily, member 6)	0.027
CCL7	chemokine (C-C motif) ligand 7	0.027	Human
CTNNB1	catenin (cadherin-associated protein), beta 1, 88kDa	0.026
ZNF529	zinc finger protein 529	0.025
REL	v-rel reticuloendotheliosis viral oncogene homolog (avian)	0.025
MAP3K8	mitogen-activated protein kinase kinase kinase 8	0.025
ZNF569	zinc finger protein 569	0.025
CCR7	chemokine (C-C motif) receptor 7	0.024
CCL3	chemokine (C-C motif) ligand 3	0.023	Human
SNAI1	snail homolog 1 (Drosophila)	0.023
PSMC1	proteasome (prosome, macropain) 26S subunit, ATPase, 1	0.023
CD83	CD83 molecule	0.023
TNFAIP3	tumor necrosis factor, alpha-induced protein 3	0.022
IFNG	interferon, gamma	0.022
ZNF432	zinc finger protein 432	0.022
PSMC5	proteasome (prosome, macropain) 26S subunit, ATPase, 5	0.022
PTGS2	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)	0.021	Rat
IKBKG	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma	0.021
CXCL13	chemokine (C-X-C motif) ligand 13	0.021
CCR4	chemokine (C-C motif) receptor 4	0.020
INHBA	inhibin, beta A	0.020
CFLAR	CASP8 and FADD-like apoptosis regulator	0.020
PPP1R16A	protein phosphatase 1, regulatory (inhibitor) subunit 16A	0.019
IL7R	interleukin 7 receptor	0.019
MMP12	matrix metallopeptidase 12 (macrophage elastase)	0.018
RCC1	regulator of chromosome condensation 1	0.018
SELE	selectin E	0.018
LY96	lymphocyte antigen 96	0.018
IL10	interleukin 10	0.018
PSMD6	proteasome (prosome, macropain) 26S subunit, non-ATPase, 6	0.018
RGS1	regulator of G-protein signaling 1	0.017
TNFAIP2	tumor necrosis factor, alpha-induced protein 2	0.017
ZNF140	zinc finger protein 140	0.016	Human
FPR3	formyl peptide receptor 3	0.016
CH25H	cholesterol 25-hydroxylase	0.016
CCL11	chemokine (C-C motif) ligand 11	0.015	Human
ACTN1	actinin, alpha 1	0.015
ARIH1	ariadne homolog, ubiquitin-conjugating enzyme E2 binding protein, 1 (Drosophila)	0.015
DDX58	DEAD (Asp-Glu-Ala-Asp) box polypeptide 58	0.015
TREM1	triggering receptor expressed on myeloid cells 1	0.015
CCL18	chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)	0.014	Human
TLR2	toll-like receptor 2	0.014
NOG	noggin	0.014
LASP1	LIM and SH3 protein 1	0.014
SERPINB2	serpin peptidase inhibitor, clade B (ovalbumin), member 2	0.014
PSMC4	proteasome (prosome, macropain) 26S subunit, ATPase, 4	0.014
TUBA1A	tubulin, alpha 1a	0.013
PTPRE	protein tyrosine phosphatase, receptor type, E	0.013
HOXA9	homeobox A9	0.013
CCL19	chemokine (C-C motif) ligand 19	0.013
TXN	thioredoxin	0.013
LATS1	LATS, large tumor suppressor, homolog 1 (Drosophila)	0.013
IER3	immediate early response 3	0.013
CD2	CD2 molecule	0.013
ZNF383	zinc finger protein 383	0.012	Human
TRIM21	tripartite motif containing 21	0.012
YAP1	Yes-associated protein 1	0.012
IFNAR1	interferon (alpha, beta and omega) receptor 1	0.012
CD80	CD80 molecule	0.012
RGS2	regulator of G-protein signaling 2, 24kDa	0.012
PSMD11	proteasome (prosome, macropain) 26S subunit, non-ATPase, 11	0.012
PSMD4	proteasome (prosome, macropain) 26S subunit, non-ATPase, 4	0.012
BTK	Bruton agammaglobulinemia tyrosine kinase	0.012
ZC3H12A	zinc finger CCCH-type containing 12A	0.012
NPLOC4	nuclear protein localization 4 homolog (S. cerevisiae)	0.011
LAT	linker for activation of T cells	0.011
VCAM1	vascular cell adhesion molecule 1	0.011
CMIP	c-Maf-inducing protein	0.011
IL2RB	interleukin 2 receptor, beta	0.011
VCP	valosin containing protein	0.011
SMAD1	SMAD family member 1	0.011
CCL1	chemokine (C-C motif) ligand 1	0.011	Human
ZNF304	zinc finger protein 304	0.011
PYDC2	pyrin domain containing 2	0.011
LILRA6	leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6	0.011
NFKBIZ	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta	0.011
LILRB1	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1	0.011
PI3	peptidase inhibitor 3, skin-derived	0.010
FLNB	filamin B, beta	0.010
LIF	leukemia inhibitory factor (cholinergic differentiation factor)	0.010
OLR1	oxidized low density lipoprotein (lectin-like) receptor 1	0.010
ZNF180	zinc finger protein 180	0.010
FERMT2	fermitin family member 2	0.010
LCP2	lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)	0.010