Homo sapiens

87 known processes

TLE2

transducin-like enhancer of split 2 (E(sp1) homolog, Drosophila)

(Aliases: ESG,GRG2,FLJ41188,ESG2)

TLE2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular ketone metabolic process GO:0042180 80 0.162
cell adhesion GO:0007155 325 0.144
regulation of cellular amine metabolic process GO:0033238 11 0.143
biological adhesion GO:0022610 331 0.118
cellular amine metabolic process GO:0044106 41 0.111
regulation of cellular ketone metabolic process GO:0010565 50 0.111
regulation of cellular amino acid metabolic process GO:0006521 6 0.106
amine metabolic process GO:0009308 44 0.105
regulation of cell differentiation GO:0045595 393 0.096
post embryonic development GO:0009791 2 0.095
cellular amino acid metabolic process GO:0006520 116 0.094
cellular response to endogenous stimulus GO:0071495 336 0.094
cellular component morphogenesis GO:0032989 314 0.086
Fly
cell projection organization GO:0030030 252 0.082
Fly
positive regulation of cell proliferation GO:0008284 301 0.078
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.075
Human Fly
positive regulation of cellular component organization GO:0051130 376 0.071
cell morphogenesis GO:0000902 296 0.069
Fly
nervous system development GO:0007399 293 0.069
Fly
positive regulation of developmental process GO:0051094 314 0.068
positive regulation of cellular amine metabolic process GO:0033240 7 0.066
negative regulation of cell death GO:0060548 345 0.066
Human
hindbrain development GO:0030902 3 0.065
forelimb morphogenesis GO:0035136 4 0.063
embryonic forelimb morphogenesis GO:0035115 4 0.062
system process GO:0003008 349 0.060
locomotory behavior GO:0007626 1 0.060
regulation of nucleotide metabolic process GO:0006140 269 0.059
regulation of cell cycle GO:0051726 393 0.057
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.057
cell development GO:0048468 328 0.057
Fly
skeletal system development GO:0001501 79 0.056
regulation of anatomical structure morphogenesis GO:0022603 286 0.056
anatomical structure formation involved in morphogenesis GO:0048646 284 0.055
small gtpase mediated signal transduction GO:0007264 78 0.055
negative regulation of apoptotic process GO:0043066 316 0.055
Human
cellular response to oxygen containing compound GO:1901701 276 0.054
negative regulation of developmental process GO:0051093 247 0.053
organ formation GO:0048645 3 0.053
purine ribonucleoside metabolic process GO:0046128 437 0.052
cardiovascular system development GO:0072358 262 0.051
nucleoside triphosphate metabolic process GO:0009141 422 0.051
pituitary gland development GO:0021983 2 0.051
negative regulation of cellular protein metabolic process GO:0032269 353 0.050
enzyme linked receptor protein signaling pathway GO:0007167 303 0.049
ribonucleotide catabolic process GO:0009261 405 0.049
negative regulation of programmed cell death GO:0043069 321 0.049
Human
negative regulation of phosphate metabolic process GO:0045936 267 0.048
circulatory system development GO:0072359 262 0.048
organ morphogenesis GO:0009887 147 0.048
negative regulation of protein metabolic process GO:0051248 391 0.048
neuron differentiation GO:0030182 138 0.047
Fly
negative regulation of phosphorus metabolic process GO:0010563 267 0.047
regulation of cell motility GO:2000145 299 0.046
response to abiotic stimulus GO:0009628 336 0.046
single organism cellular localization GO:1902580 332 0.045
regulation of protein kinase activity GO:0045859 289 0.044
purine containing compound catabolic process GO:0072523 411 0.044
negative regulation of multicellular organismal process GO:0051241 317 0.043
regulation of kinase activity GO:0043549 314 0.043
nucleoside phosphate catabolic process GO:1901292 412 0.043
ras protein signal transduction GO:0007265 73 0.042
positive regulation of cell differentiation GO:0045597 211 0.042
purine nucleoside catabolic process GO:0006152 398 0.042
female gamete generation GO:0007292 2 0.042
negative regulation of catalytic activity GO:0043086 335 0.042
positive regulation of cell death GO:0010942 263 0.041
generation of neurons GO:0048699 152 0.041
Fly
oogenesis GO:0048477 2 0.041
positive regulation of phosphorylation GO:0042327 394 0.041
hematopoietic or lymphoid organ development GO:0048534 186 0.041
regulation of cell cycle process GO:0010564 266 0.040
regulation of purine nucleotide metabolic process GO:1900542 264 0.040
positive regulation of hydrolase activity GO:0051345 331 0.039
determination of adult lifespan GO:0008340 2 0.039
protein localization to organelle GO:0033365 280 0.039
positive regulation of protein phosphorylation GO:0001934 313 0.039
ribonucleoside triphosphate catabolic process GO:0009203 391 0.039
metal ion transport GO:0030001 272 0.039
regulation of cellular component movement GO:0051270 334 0.038
multicellular organismal aging GO:0010259 3 0.038
neuromuscular junction development GO:0007528 3 0.038
lipid metabolic process GO:0006629 381 0.038
apoptotic signaling pathway GO:0097190 268 0.038
regulation of locomotion GO:0040012 329 0.038
cell morphogenesis involved in differentiation GO:0000904 144 0.038
Fly
regulation of transferase activity GO:0051338 355 0.037
cytoplasmic transport GO:0016482 379 0.037
tube development GO:0035295 125 0.037
negative regulation of cell migration GO:0030336 102 0.037
cell fate determination GO:0001709 3 0.037
regulation of protein localization GO:0032880 296 0.037
negative regulation of cell proliferation GO:0008285 228 0.036
epithelium development GO:0060429 227 0.036
ribonucleoside triphosphate metabolic process GO:0009199 412 0.036
glycosyl compound catabolic process GO:1901658 413 0.036
purine nucleoside triphosphate metabolic process GO:0009144 412 0.036
nerve development GO:0021675 4 0.036
response to oxygen containing compound GO:1901700 369 0.035
purine nucleoside triphosphate catabolic process GO:0009146 392 0.035
epithelial cell differentiation GO:0030855 141 0.035
negative regulation of canonical wnt signaling pathway GO:0090090 55 0.035
regulation of cell migration GO:0030334 289 0.035
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.034
purine nucleotide catabolic process GO:0006195 405 0.034
actin filament based process GO:0030029 224 0.034
Fly
carbohydrate derivative biosynthetic process GO:1901137 207 0.034
neurogenesis GO:0022008 169 0.034
Fly
nucleoside triphosphate catabolic process GO:0009143 394 0.034
segmentation GO:0035282 4 0.034
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.034
purine ribonucleoside catabolic process GO:0046130 398 0.034
mitotic cell cycle GO:0000278 326 0.033
central nervous system development GO:0007417 123 0.033
nucleotide catabolic process GO:0009166 408 0.033
cation transport GO:0006812 331 0.033
secretion GO:0046903 254 0.033
morphogenesis of embryonic epithelium GO:0016331 4 0.033
neuron fate commitment GO:0048663 2 0.033
spinal cord development GO:0021510 4 0.033
cartilage condensation GO:0001502 1 0.032
ossification GO:0001503 121 0.032
negative regulation of cell differentiation GO:0045596 171 0.032
nucleoside catabolic process GO:0009164 408 0.032
urogenital system development GO:0001655 65 0.032
salivary gland morphogenesis GO:0007435 4 0.031
positive regulation of cell cycle process GO:0090068 106 0.031
organophosphate catabolic process GO:0046434 430 0.031
positive regulation of programmed cell death GO:0043068 249 0.031
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.031
adult locomotory behavior GO:0008344 1 0.030
renal system development GO:0072001 63 0.030
purine ribonucleotide catabolic process GO:0009154 404 0.030
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.030
positive regulation of transport GO:0051050 336 0.030
regulation of small gtpase mediated signal transduction GO:0051056 156 0.030
negative regulation of protein modification process GO:0031400 200 0.029
signal transduction by phosphorylation GO:0023014 297 0.029
blastoderm segmentation GO:0007350 2 0.029
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.029
response to lipid GO:0033993 206 0.029
regulation of cell growth GO:0001558 135 0.029
guanosine containing compound catabolic process GO:1901069 239 0.029
positive regulation of catabolic process GO:0009896 310 0.029
single organismal cell cell adhesion GO:0016337 148 0.029
cell division GO:0051301 168 0.029
wnt signaling pathway GO:0016055 156 0.028
brain development GO:0007420 97 0.028
intracellular protein transport GO:0006886 270 0.028
regulation of mitotic cell cycle GO:0007346 189 0.028
gtp catabolic process GO:0006184 237 0.028
regulation of proteolysis GO:0030162 293 0.028
peptidyl tyrosine phosphorylation GO:0018108 170 0.028
positive regulation of locomotion GO:0040017 186 0.028
regulation of cytokine production GO:0001817 232 0.028
positive regulation of organelle organization GO:0010638 195 0.028
regulation of nucleoside metabolic process GO:0009118 209 0.028
regulation of wnt signaling pathway GO:0030111 123 0.028
positive regulation of apoptotic process GO:0043065 246 0.028
regulation of gtp catabolic process GO:0033124 180 0.027
cellular macromolecule catabolic process GO:0044265 380 0.027
positive regulation of gtpase activity GO:0043547 166 0.027
regulation of cell adhesion GO:0030155 166 0.027
regulation of cellular component biogenesis GO:0044087 281 0.027
regulation of mapk cascade GO:0043408 262 0.027
positive regulation of cell cycle GO:0045787 140 0.027
kidney development GO:0001822 53 0.027
stem cell differentiation GO:0048863 93 0.027
mitotic cell cycle process GO:1903047 286 0.027
positive regulation of immune system process GO:0002684 283 0.027
nuclear transport GO:0051169 179 0.027
immune system development GO:0002520 195 0.027
head development GO:0060322 108 0.026
regulation of binding GO:0051098 111 0.026
gtp metabolic process GO:0046039 239 0.026
single organism cell adhesion GO:0098602 179 0.026
negative regulation of intracellular signal transduction GO:1902532 183 0.026
Human
nitrogen compound transport GO:0071705 191 0.026
response to wounding GO:0009611 168 0.026
response to growth factor GO:0070848 205 0.026
negative regulation of phosphorylation GO:0042326 174 0.026
histone modification GO:0016570 251 0.026
taxis GO:0042330 157 0.025
negative regulation of cell cycle GO:0045786 193 0.025
protein targeting GO:0006605 187 0.025
cell substrate adhesion GO:0031589 132 0.025
somatic stem cell maintenance GO:0035019 4 0.025
chemical homeostasis GO:0048878 306 0.025
positive regulation of nucleotide catabolic process GO:0030813 185 0.025
guanosine containing compound metabolic process GO:1901068 244 0.025
regulation of establishment of protein localization GO:0070201 242 0.025
peptidyl tyrosine modification GO:0018212 170 0.025
negative regulation of cellular amine metabolic process GO:0033239 3 0.025
muscle structure development GO:0061061 98 0.025
neural tube patterning GO:0021532 2 0.024
regulation of ras protein signal transduction GO:0046578 155 0.024
regulation of growth GO:0040008 165 0.024
regulation of cell development GO:0060284 161 0.024
hindlimb morphogenesis GO:0035137 2 0.024
vesicle mediated transport GO:0016192 371 0.024
ribonucleoside catabolic process GO:0042454 406 0.024
hemopoiesis GO:0030097 180 0.024
regulation of secretion GO:0051046 194 0.024
regulation of cell morphogenesis GO:0022604 153 0.024
peripheral nervous system development GO:0007422 2 0.024
regulation of peptidase activity GO:0052547 180 0.024
cellular response to growth factor stimulus GO:0071363 197 0.024
cranial nerve development GO:0021545 4 0.024
blood vessel development GO:0001568 172 0.023
negative regulation of locomotion GO:0040013 118 0.023
anterior posterior axis specification GO:0009948 2 0.023
regulation of nervous system development GO:0051960 88 0.023
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.023
mapk cascade GO:0000165 288 0.023
cell growth GO:0016049 160 0.023
protein localization to nucleus GO:0034504 136 0.023
dephosphorylation GO:0016311 209 0.023
response to hormone GO:0009725 175 0.023
nucleocytoplasmic transport GO:0006913 176 0.023
protein catabolic process GO:0030163 325 0.022
cellular lipid metabolic process GO:0044255 303 0.022
cell activation GO:0001775 213 0.022
intrinsic apoptotic signaling pathway GO:0097193 127 0.022
cytokine production GO:0001816 247 0.022
positive regulation of gtp catabolic process GO:0033126 166 0.022
regeneration GO:0031099 4 0.022
negative regulation of cell motility GO:2000146 104 0.022
negative regulation of cellular component organization GO:0051129 235 0.022
regulation of purine nucleotide catabolic process GO:0033121 205 0.022
chromatin modification GO:0016568 298 0.022
carbohydrate metabolic process GO:0005975 207 0.022
regulation of protein transport GO:0051223 213 0.022
embryonic hindlimb morphogenesis GO:0035116 2 0.022
cell type specific apoptotic process GO:0097285 125 0.022
cellular response to nitrogen compound GO:1901699 144 0.021
endomembrane system organization GO:0010256 196 0.021
regulation of intracellular transport GO:0032386 195 0.021
actin filament organization GO:0007015 128 0.021
Fly
cellular macromolecular complex assembly GO:0034622 324 0.021
regulation of cellular response to stress GO:0080135 244 0.021
response to organic cyclic compound GO:0014070 204 0.021
thymus development GO:0048538 3 0.021
neuron development GO:0048666 113 0.021
Fly
embryonic epithelial tube formation GO:0001838 4 0.021
mesenchyme development GO:0060485 59 0.021
nucleotide biosynthetic process GO:0009165 109 0.021
connective tissue development GO:0061448 39 0.021
cellular protein catabolic process GO:0044257 261 0.021
inner ear morphogenesis GO:0042472 4 0.021
organonitrogen compound biosynthetic process GO:1901566 200 0.021
embryonic morphogenesis GO:0048598 85 0.021
growth GO:0040007 202 0.021
cell aggregation GO:0098743 1 0.021
sex determination GO:0007530 3 0.021
regulation of hormone levels GO:0010817 125 0.021
positive regulation of cellular catabolic process GO:0031331 284 0.021
nucleoside phosphate biosynthetic process GO:1901293 109 0.021
neuron projection development GO:0031175 106 0.021
Fly
regulation of nucleotide catabolic process GO:0030811 205 0.020
cell projection morphogenesis GO:0048858 129 0.020
Fly
muscle system process GO:0003012 81 0.020
membrane organization GO:0061024 292 0.020
immune response GO:0006955 307 0.020
positive regulation of nucleotide metabolic process GO:0045981 230 0.020
rho protein signal transduction GO:0007266 26 0.020
negative regulation of hydrolase activity GO:0051346 182 0.020
chromatin organization GO:0006325 351 0.020
blood vessel morphogenesis GO:0048514 162 0.020
establishment of protein localization to organelle GO:0072594 172 0.020
peptidyl lysine modification GO:0018205 144 0.020
regulation of neuron differentiation GO:0045664 70 0.020
protein acylation GO:0043543 138 0.020
regulation of intracellular protein transport GO:0033157 123 0.020
cell part morphogenesis GO:0032990 137 0.020
Fly
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 125 0.020
protein maturation GO:0051604 233 0.020
positive regulation of protein kinase activity GO:0045860 190 0.020
embryonic placenta development GO:0001892 1 0.020
lung alveolus development GO:0048286 4 0.019
covalent chromatin modification GO:0016569 254 0.019
protein targeting to nucleus GO:0044744 104 0.019
ameboidal type cell migration GO:0001667 135 0.019
neural crest cell development GO:0014032 3 0.019
transmembrane transport GO:0055085 399 0.019
tissue migration GO:0090130 119 0.019
epithelial cell migration GO:0010631 119 0.019
chemotaxis GO:0006935 157 0.019
positive regulation of ras gtpase activity GO:0032320 117 0.019
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.019
rostrocaudal neural tube patterning GO:0021903 1 0.019
regulation of ras gtpase activity GO:0032318 128 0.019
protein import into nucleus GO:0006606 104 0.019
regulation of endopeptidase activity GO:0052548 170 0.019
mesenchymal cell differentiation GO:0048762 52 0.019
cellular response to organonitrogen compound GO:0071417 124 0.019
inorganic ion transmembrane transport GO:0098660 231 0.019
leukocyte activation GO:0045321 164 0.019
morphogenesis of an epithelium GO:0002009 60 0.019
neuroblast proliferation GO:0007405 4 0.019
neurotransmitter secretion GO:0007269 4 0.019
single organism carbohydrate metabolic process GO:0044723 193 0.019
metencephalon development GO:0022037 2 0.019
mesenchymal cell development GO:0014031 50 0.019
regulation of cytoskeleton organization GO:0051493 177 0.018
specification of organ identity GO:0010092 3 0.018
negative regulation of cellular component movement GO:0051271 106 0.018
protein modification by small protein conjugation GO:0032446 342 0.018
regulation of neural precursor cell proliferation GO:2000177 4 0.018
negative regulation of immune system process GO:0002683 136 0.018
vasculature development GO:0001944 181 0.018
organelle fission GO:0048285 149 0.018
heart formation GO:0060914 2 0.018
cellular response to organic cyclic compound GO:0071407 127 0.018
regulation of stem cell differentiation GO:2000736 56 0.018
heart development GO:0007507 95 0.018
response to nitrogen compound GO:1901698 184 0.018
actin cytoskeleton organization GO:0030036 207 0.018
Fly
coagulation GO:0050817 78 0.018
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.018
regulation of gtpase activity GO:0043087 180 0.018
regulation of cysteine type endopeptidase activity GO:2000116 127 0.018
regulation of reactive oxygen species metabolic process GO:2000377 41 0.018
ectodermal placode formation GO:0060788 1 0.018
regulation of multi organism process GO:0043900 157 0.018
posttranscriptional regulation of gene expression GO:0010608 213 0.018
regulation of odontogenesis GO:0042481 4 0.018
negative regulation of transferase activity GO:0051348 124 0.018
ectodermal placode development GO:0071696 1 0.018
forebrain regionalization GO:0021871 3 0.018
anterior posterior axis specification embryo GO:0008595 2 0.018
regulation of protein localization to nucleus GO:1900180 85 0.017
secretion by cell GO:0032940 226 0.017
oxidation reduction process GO:0055114 396 0.017
positive regulation of cell migration GO:0030335 172 0.017
positive regulation of cell motility GO:2000147 177 0.017
lipid biosynthetic process GO:0008610 177 0.017
positive regulation of neural precursor cell proliferation GO:2000179 2 0.017
organophosphate biosynthetic process GO:0090407 163 0.017
positive regulation of nucleoside metabolic process GO:0045979 186 0.017
divalent inorganic cation transport GO:0072511 158 0.017
negative regulation of gliogenesis GO:0014014 3 0.017
neurological system process GO:0050877 163 0.017
regulation of axon guidance GO:1902667 3 0.017
regulation of nucleocytoplasmic transport GO:0046822 98 0.017
protein import GO:0017038 130 0.017
memory GO:0007613 3 0.017
single organism membrane organization GO:0044802 268 0.017
cell cell signaling GO:0007267 155 0.017
Fly
embryo development GO:0009790 123 0.017
epithelial cell fate commitment GO:0072148 3 0.017
protein ubiquitination GO:0016567 314 0.017
ribose phosphate biosynthetic process GO:0046390 82 0.017
regulation of meiotic cell cycle GO:0051445 4 0.017
cellular response to dna damage stimulus GO:0006974 379 0.017
neural tube formation GO:0001841 3 0.017
ion homeostasis GO:0050801 230 0.016
regulation of cell division GO:0051302 116 0.016
cation transmembrane transport GO:0098655 238 0.016
regulation of cell projection organization GO:0031344 107 0.016
regulation of protein stability GO:0031647 87 0.016
oocyte development GO:0048599 1 0.016
tissue morphogenesis GO:0048729 96 0.016
negative regulation of cell adhesion GO:0007162 64 0.016
astrocyte differentiation GO:0048708 4 0.016
regulation of dna metabolic process GO:0051052 153 0.016
single organism nuclear import GO:1902593 104 0.016
plasma membrane organization GO:0007009 115 0.016
purine containing compound biosynthetic process GO:0072522 88 0.016
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.016
microtubule based process GO:0007017 210 0.016
forebrain generation of neurons GO:0021872 3 0.016
negative regulation of protein phosphorylation GO:0001933 140 0.016
cellular response to lipid GO:0071396 127 0.016
somatic muscle development GO:0007525 1 0.016
motor neuron axon guidance GO:0008045 2 0.016
angiogenesis GO:0001525 147 0.016
regulation of response to external stimulus GO:0032101 222 0.016
compound eye development GO:0048749 1 0.016
positive regulation of synaptic transmission GO:0050806 4 0.016
positive regulation of cell development GO:0010720 92 0.016
anion transport GO:0006820 161 0.016
regulation of ion transport GO:0043269 189 0.016
regulation of peptidyl tyrosine phosphorylation GO:0050730 108 0.015
mesonephric duct development GO:0072177 3 0.015
regulation of stress activated mapk cascade GO:0032872 84 0.015
neuroendocrine cell differentiation GO:0061101 2 0.015
morphogenesis of a polarized epithelium GO:0001738 3 0.015
positive regulation of transferase activity GO:0051347 227 0.015
negative regulation of cell growth GO:0030308 83 0.015
cellular chemical homeostasis GO:0055082 180 0.015
maintenance of location GO:0051235 112 0.015
microtubule cytoskeleton organization GO:0000226 176 0.015
defense response GO:0006952 315 0.015
positive regulation of mapk cascade GO:0043410 190 0.015
protein acetylation GO:0006473 116 0.015
glycoprotein metabolic process GO:0009100 110 0.015
negative regulation of protein processing GO:0010955 142 0.015
positive regulation of kinase activity GO:0033674 204 0.015
digestive tract development GO:0048565 75 0.015
mesenchymal to epithelial transition involved in metanephros morphogenesis GO:0003337 4 0.015
regulation of cytoplasmic transport GO:1903649 149 0.015
nuclear import GO:0051170 106 0.015
cellular response to cytokine stimulus GO:0071345 181 0.015
reproductive process GO:0022414 106 0.015
cellular response to hormone stimulus GO:0032870 125 0.015
innate immune response GO:0045087 178 0.015
positive regulation of cellular component biogenesis GO:0044089 158 0.015
cardiac muscle cell contraction GO:0086003 4 0.015
spermatid differentiation GO:0048515 4 0.015
regulation of protein processing GO:0070613 150 0.015
ion transmembrane transport GO:0034220 338 0.015
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 89 0.015
response to oxygen levels GO:0070482 100 0.015
cellular homeostasis GO:0019725 196 0.015
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 90 0.015
mitotic nuclear division GO:0007067 119 0.015
rhythmic behavior GO:0007622 2 0.015
stress activated protein kinase signaling cascade GO:0031098 94 0.015
tripartite regional subdivision GO:0007351 2 0.015
response to cytokine GO:0034097 232 0.015
regulation of epithelial cell migration GO:0010632 93 0.015
pharynx development GO:0060465 1 0.015
regulation of protein maturation GO:1903317 150 0.015
proteasomal protein catabolic process GO:0010498 176 0.015
osteoblast differentiation GO:0001649 92 0.015
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 85 0.015
stem cell development GO:0048864 69 0.015
digestive system development GO:0055123 75 0.015
regulation of apoptotic signaling pathway GO:2001233 175 0.014
sodium ion transport GO:0006814 61 0.014
regulation of endothelial cell migration GO:0010594 67 0.014
negative regulation of kinase activity GO:0033673 106 0.014
metanephric nephron tubule development GO:0072234 3 0.014
negative regulation of wnt signaling pathway GO:0030178 69 0.014
mitotic cell cycle phase transition GO:0044772 162 0.014
embryonic camera type eye development GO:0031076 2 0.014
protein processing GO:0016485 226 0.014
regulation of cyclic nucleotide metabolic process GO:0030799 63 0.014
response to hypoxia GO:0001666 96 0.014
cell projection assembly GO:0030031 126 0.014
cell chemotaxis GO:0060326 112 0.014
myeloid cell differentiation GO:0030099 117 0.014
cyclic nucleotide biosynthetic process GO:0009190 61 0.014
endocrine system development GO:0035270 26 0.014
spermatid development GO:0007286 4 0.014
regulation of neurotransmitter secretion GO:0046928 3 0.014
bmp signaling pathway GO:0030509 49 0.014
endothelial cell migration GO:0043542 86 0.014
limbic system development GO:0021761 3 0.014
protein localization to membrane GO:0072657 160 0.014
cellular response to transforming growth factor beta stimulus GO:0071560 94 0.014
regulation of cyclic nucleotide biosynthetic process GO:0030802 49 0.014
negative regulation of endopeptidase activity GO:0010951 84 0.014
organic acid biosynthetic process GO:0016053 97 0.014
reactive oxygen species metabolic process GO:0072593 75 0.014
hair cell differentiation GO:0035315 2 0.014
regulation of organ formation GO:0003156 4 0.014
response to organonitrogen compound GO:0010243 156 0.014
calcium ion transport GO:0006816 147 0.014
inorganic cation transmembrane transport GO:0098662 194 0.014
signal release GO:0023061 70 0.014
regulation of actin filament based process GO:0032970 141 0.014
regulation of erk1 and erk2 cascade GO:0070372 99 0.013
positive regulation of cellular component movement GO:0051272 181 0.013
response to decreased oxygen levels GO:0036293 96 0.013
ventral spinal cord development GO:0021517 1 0.013
mesonephros development GO:0001823 17 0.013
negative regulation of organelle organization GO:0010639 126 0.013
oocyte differentiation GO:0009994 2 0.013
midbrain development GO:0030901 45 0.013
regulation of actin cytoskeleton organization GO:0032956 116 0.013
negative regulation of proteolysis GO:0045861 132 0.013
negative regulation of protein maturation GO:1903318 142 0.013
regulation of cell activation GO:0050865 125 0.013
long term memory GO:0007616 2 0.013
regulation of meiosis GO:0040020 3 0.013
regulation of epithelial cell proliferation GO:0050678 113 0.013
cell junction organization GO:0034330 79 0.013
regulation of protein catabolic process GO:0042176 155 0.013
small molecule biosynthetic process GO:0044283 157 0.013

TLE2 disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 295 0.034
inherited metabolic disorder DOID:655 242 0.033
musculoskeletal system disease DOID:17 223 0.031
muscular disease DOID:0080000 114 0.028
sensory system disease DOID:0050155 203 0.019
nervous system disease DOID:863 431 0.019
muscle tissue disease DOID:66 113 0.018
cancer DOID:162 167 0.015
disease of cellular proliferation DOID:14566 174 0.015
central nervous system disease DOID:331 186 0.015
myopathy DOID:423 104 0.015
organ system cancer DOID:0050686 164 0.014
cardiovascular system disease DOID:1287 106 0.013