Homo sapiens

102 known processes

IRF4

interferon regulatory factor 4

(Aliases: LSIRF,MUM1)

IRF4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
chemokine c c motif ligand 11 production GO:0071954 1 0.992
interleukin 8 mediated signaling pathway GO:0038112 2 0.926
cell activation GO:0001775 213 0.915
Mouse
myeloid dendritic cell chemotaxis GO:0002408 3 0.914
lymphocyte activation GO:0046649 133 0.912
Mouse
leukocyte activation GO:0045321 164 0.904
Mouse
positive regulation of immune system process GO:0002684 283 0.897
Mouse
chemokine c c motif ligand 19 signaling pathway GO:0038115 1 0.893
chemokine c c motif ligand 21 signaling pathway GO:0038116 1 0.880
immune response GO:0006955 307 0.848
Human Mouse
regulation of astrocyte chemotaxis GO:2000458 1 0.845
astrocyte chemotaxis GO:0035700 1 0.790
response to cytokine GO:0034097 232 0.778
Human
positive regulation of cell proliferation GO:0008284 301 0.742
hematopoietic or lymphoid organ development GO:0048534 186 0.732
Mouse
defense response GO:0006952 315 0.723
Human Mouse
positive regulation of phosphorylation GO:0042327 394 0.683
g protein coupled receptor signaling pathway GO:0007186 207 0.673
positive regulation of astrocyte chemotaxis GO:2000464 1 0.666
cytokine production GO:0001816 247 0.653
regulation of leukocyte activation GO:0002694 115 0.646
cytokine mediated signaling pathway GO:0019221 109 0.634
positive regulation of mapk cascade GO:0043410 190 0.628
hemopoiesis GO:0030097 180 0.601
Mouse
response to other organism GO:0051707 261 0.583
Human Mouse
regulation of cytokine production GO:0001817 232 0.575
regulation of cell differentiation GO:0045595 393 0.566
response to biotic stimulus GO:0009607 276 0.560
Human Mouse
mononuclear cell proliferation GO:0032943 71 0.542
negative regulation of multicellular organismal process GO:0051241 317 0.535
regulation of lymphocyte activation GO:0051249 103 0.516
regulation of mononuclear cell proliferation GO:0032944 65 0.516
t cell activation GO:0042110 99 0.515
Mouse
immune system development GO:0002520 195 0.496
Mouse
response to external biotic stimulus GO:0043207 261 0.479
Human Mouse
signal transduction by phosphorylation GO:0023014 297 0.455
lymphocyte proliferation GO:0046651 70 0.438
positive regulation of developmental process GO:0051094 314 0.422
cellular defense response GO:0006968 2 0.419
positive regulation of cellular amine metabolic process GO:0033240 7 0.399
cellular response to cytokine stimulus GO:0071345 181 0.397
Human
leukocyte differentiation GO:0002521 98 0.385
Mouse
negative regulation of cell death GO:0060548 345 0.383
positive regulation of protein phosphorylation GO:0001934 313 0.380
regulation of cellular ketone metabolic process GO:0010565 50 0.380
regulation of myeloid leukocyte differentiation GO:0002761 39 0.376
cellular amine metabolic process GO:0044106 41 0.376
leukocyte proliferation GO:0070661 74 0.374
negative regulation of apoptotic process GO:0043066 316 0.373
negative regulation of cell proliferation GO:0008285 228 0.368
regulation of response to external stimulus GO:0032101 222 0.367
myeloid cell differentiation GO:0030099 117 0.366
Mouse
erk1 and erk2 cascade GO:0070371 104 0.362
negative regulation of developmental process GO:0051093 247 0.360
positive regulation of lymphocyte proliferation GO:0050671 46 0.347
regulation of lymphocyte proliferation GO:0050670 64 0.334
positive regulation of cytoplasmic transport GO:1903651 82 0.333
regulation of cellular amine metabolic process GO:0033238 11 0.332
positive regulation of leukocyte proliferation GO:0070665 48 0.330
positive regulation of lymphocyte activation GO:0051251 73 0.328
regulation of cell activation GO:0050865 125 0.323
regulation of cellular amino acid metabolic process GO:0006521 6 0.318
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.311
regulation of leukocyte differentiation GO:1902105 61 0.308
immune effector process GO:0002252 159 0.306
Human Mouse
regulation of mapk cascade GO:0043408 262 0.296
cellular ketone metabolic process GO:0042180 80 0.292
negative regulation of programmed cell death GO:0043069 321 0.285
positive regulation of cell activation GO:0050867 81 0.283
regulation of anatomical structure morphogenesis GO:0022603 286 0.277
positive regulation of leukocyte activation GO:0002696 80 0.276
cellular divalent inorganic cation homeostasis GO:0072503 128 0.272
cellular amino acid metabolic process GO:0006520 116 0.271
positive regulation of immune response GO:0050778 159 0.270
Mouse
response to oxygen containing compound GO:1901700 369 0.266
positive regulation of erk1 and erk2 cascade GO:0070374 75 0.262
mapk cascade GO:0000165 288 0.259
regulation of myeloid cell differentiation GO:0045637 81 0.258
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.257
positive regulation of cell differentiation GO:0045597 211 0.253
cellular response to oxygen containing compound GO:1901701 276 0.250
response to bacterium GO:0009617 144 0.248
cation transport GO:0006812 331 0.248
regulation of biomineral tissue development GO:0070167 31 0.245
regulation of protein kinase activity GO:0045859 289 0.241
positive regulation of cell death GO:0010942 263 0.238
regulation of bone mineralization GO:0030500 29 0.232
bone mineralization GO:0030282 34 0.231
positive regulation of programmed cell death GO:0043068 249 0.229
peptidyl tyrosine modification GO:0018212 170 0.227
amine metabolic process GO:0009308 44 0.226
response to virus GO:0009615 126 0.225
Human
leukocyte migration GO:0050900 107 0.216
regulation of t cell activation GO:0050863 77 0.214
positive regulation of behavior GO:0048520 60 0.212
lymphocyte mediated immunity GO:0002449 48 0.207
positive regulation of apoptotic process GO:0043065 246 0.203
metal ion homeostasis GO:0055065 169 0.201
positive regulation of mononuclear cell proliferation GO:0032946 47 0.200
regulation of cellular component movement GO:0051270 334 0.199
epithelial cell proliferation GO:0050673 128 0.197
response to lipid GO:0033993 206 0.197
adaptive immune response GO:0002250 49 0.195
Human Mouse
regulation of osteoclast differentiation GO:0045670 18 0.195
positive regulation of protein kinase activity GO:0045860 190 0.194
negative regulation of bone mineralization GO:0030502 7 0.188
regulation of cell migration GO:0030334 289 0.184
positive regulation of cytosolic calcium ion concentration GO:0007204 82 0.181
positive regulation of cellular component organization GO:0051130 376 0.180
regulation of transferase activity GO:0051338 355 0.180
positive regulation of kinase activity GO:0033674 204 0.180
eosinophil activation involved in immune response GO:0002278 2 0.178
cell chemotaxis GO:0060326 112 0.176
regulation of kinase activity GO:0043549 314 0.174
ossification GO:0001503 121 0.173
regulation of locomotion GO:0040012 329 0.173
osteoclast differentiation GO:0030316 21 0.173
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 40 0.172
Mouse
cellular homeostasis GO:0019725 196 0.171
chemokine production GO:0032602 32 0.171
sequestering of calcium ion GO:0051208 17 0.171
endothelial cell proliferation GO:0001935 65 0.168
regulation of immune response GO:0050776 201 0.167
Human Mouse
positive regulation of osteoclast differentiation GO:0045672 9 0.166
myeloid leukocyte activation GO:0002274 34 0.165
Mouse
regulation of purine nucleotide metabolic process GO:1900542 264 0.165
blood vessel morphogenesis GO:0048514 162 0.164
small gtpase mediated signal transduction GO:0007264 78 0.163
secretion by cell GO:0032940 226 0.161
cation homeostasis GO:0055080 189 0.159
regulation of cell motility GO:2000145 299 0.158
myeloid leukocyte differentiation GO:0002573 60 0.156
Mouse
positive regulation of myeloid leukocyte differentiation GO:0002763 24 0.155
cellular ion homeostasis GO:0006873 168 0.155
anatomical structure formation involved in morphogenesis GO:0048646 284 0.155
regulation of epithelial cell proliferation GO:0050678 113 0.154
regulation of calcium ion transport into cytosol GO:0010522 33 0.152
calcium ion transport GO:0006816 147 0.151
angiogenesis GO:0001525 147 0.151
regulation of leukocyte chemotaxis GO:0002688 46 0.150
calcium ion homeostasis GO:0055074 122 0.149
chemical homeostasis GO:0048878 306 0.149
positive regulation of intracellular transport GO:0032388 104 0.148
regulation of erk1 and erk2 cascade GO:0070372 99 0.147
response to lipopolysaccharide GO:0032496 70 0.147
positive regulation of calcium ion transport GO:0051928 51 0.145
regulation of nucleotide metabolic process GO:0006140 269 0.145
cytosolic calcium ion homeostasis GO:0051480 89 0.145
positive regulation of nucleotide metabolic process GO:0045981 230 0.143
regulation of ossification GO:0030278 58 0.143
cytoplasmic transport GO:0016482 379 0.140
negative regulation of homeostatic process GO:0032845 59 0.140
leukocyte mediated immunity GO:0002443 59 0.139
positive regulation of chemotaxis GO:0050921 57 0.139
circulatory system development GO:0072359 262 0.138
regulation of protein transport GO:0051223 213 0.138
positive regulation of neutrophil migration GO:1902624 7 0.138
blood vessel development GO:0001568 172 0.137
cellular response to endogenous stimulus GO:0071495 336 0.137
positive regulation of cytokine production GO:0001819 167 0.137
regulation of intracellular transport GO:0032386 195 0.131
response to wounding GO:0009611 168 0.131
biomineral tissue development GO:0031214 39 0.129
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.129
secretion GO:0046903 254 0.127
regulation of establishment of protein localization GO:0070201 242 0.127
cellular metal ion homeostasis GO:0006875 146 0.126
peptidyl tyrosine phosphorylation GO:0018108 170 0.126
exocytosis GO:0006887 71 0.125
regulation of response to wounding GO:1903034 101 0.125
positive regulation of calcium ion transport into cytosol GO:0010524 20 0.124
negative regulation of immune system process GO:0002683 136 0.124
Mouse
positive regulation of leukocyte chemotaxis GO:0002690 38 0.123
positive regulation of t cell activation GO:0050870 54 0.122
divalent inorganic cation transport GO:0072511 158 0.121
cellular cation homeostasis GO:0030003 163 0.119
regulation of neutrophil migration GO:1902622 10 0.119
sequestering of metal ion GO:0051238 24 0.118
negative regulation of epithelial cell proliferation GO:0050680 48 0.118
regulation of camp metabolic process GO:0030814 52 0.115
regulation of cell cycle GO:0051726 393 0.115
Human
positive regulation of leukocyte migration GO:0002687 46 0.114
cyclic nucleotide metabolic process GO:0009187 82 0.114
innate immune response GO:0045087 178 0.113
response to abiotic stimulus GO:0009628 336 0.112
Human
regulation of ion transport GO:0043269 189 0.111
regulation of cyclic nucleotide metabolic process GO:0030799 63 0.110
negative regulation of t cell cytokine production GO:0002725 4 0.110
cellular response to lipid GO:0071396 127 0.110
cellular chemical homeostasis GO:0055082 180 0.108
response to molecule of bacterial origin GO:0002237 82 0.108
divalent inorganic cation homeostasis GO:0072507 136 0.108
regulation of chemotaxis GO:0050920 74 0.107
divalent metal ion transport GO:0070838 152 0.107
regulation of cytoplasmic transport GO:1903649 149 0.107
inflammatory response GO:0006954 79 0.107
positive regulation of locomotion GO:0040017 186 0.106
positive regulation of response to external stimulus GO:0032103 88 0.106
mature natural killer cell chemotaxis GO:0035782 1 0.105
positive regulation of cellular component movement GO:0051272 181 0.104
response to organic cyclic compound GO:0014070 204 0.104
positive regulation of leukocyte differentiation GO:1902107 37 0.104
positive regulation of cell migration GO:0030335 172 0.103
cell morphogenesis GO:0000902 296 0.102
regulation of ion homeostasis GO:2000021 73 0.101
lymphocyte differentiation GO:0030098 35 0.101
Mouse
positive regulation of transport GO:0051050 336 0.101
regulation of defense response GO:0031347 154 0.100
Mouse
metal ion transport GO:0030001 272 0.100
regulation of secretion GO:0051046 194 0.099
cell cell signaling GO:0007267 155 0.099
leukocyte chemotaxis GO:0030595 76 0.098
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.098
regulation of leukocyte proliferation GO:0070663 67 0.097
negative regulation of vasculature development GO:1901343 43 0.096
vesicle mediated transport GO:0016192 371 0.095
second messenger mediated signaling GO:0019932 78 0.095
positive regulation of ion transport GO:0043270 87 0.095
regulation of immune effector process GO:0002697 91 0.094
positive regulation of cell motility GO:2000147 177 0.094
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 29 0.094
regulation of metal ion transport GO:0010959 120 0.093
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.092
cytokine biosynthetic process GO:0042089 37 0.092
positive regulation of hydrolase activity GO:0051345 331 0.092
ion homeostasis GO:0050801 230 0.090
eosinophil mediated immunity GO:0002447 2 0.090
positive regulation of transferase activity GO:0051347 227 0.086
regulation of endothelial cell proliferation GO:0001936 56 0.086
vasculature development GO:0001944 181 0.085
cellular calcium ion homeostasis GO:0006874 117 0.084
regulation of secretion by cell GO:1903530 177 0.082
positive regulation of cell cycle GO:0045787 140 0.082
positive regulation of camp metabolic process GO:0030816 41 0.082
cell activation involved in immune response GO:0002263 30 0.082
Mouse
camp metabolic process GO:0046058 61 0.082
positive regulation of t cell proliferation GO:0042102 33 0.081
negative regulation of protein metabolic process GO:0051248 391 0.081
enzyme linked receptor protein signaling pathway GO:0007167 303 0.081
epithelium development GO:0060429 227 0.081
chemokine mediated signaling pathway GO:0070098 16 0.081
response to cholesterol GO:0070723 11 0.079
regulation of homeostatic process GO:0032844 121 0.079
regulation of neutrophil chemotaxis GO:0090022 10 0.079
t cell proliferation GO:0042098 45 0.079
camp mediated signaling GO:0019933 23 0.078
covalent chromatin modification GO:0016569 254 0.077
Mouse
b cell activation GO:0042113 33 0.076
cellular response to tumor necrosis factor GO:0071356 63 0.076
negative regulation of cellular protein metabolic process GO:0032269 353 0.076
positive regulation of cellular catabolic process GO:0031331 284 0.075
taxis GO:0042330 157 0.075
post embryonic development GO:0009791 2 0.075
intracellular protein transport GO:0006886 270 0.075
cellular response to biotic stimulus GO:0071216 71 0.075
i kappab kinase nf kappab signaling GO:0007249 166 0.074
maintenance of location GO:0051235 112 0.073
positive regulation of i kappab kinase nf kappab signaling GO:0043123 132 0.072
regulation of sequestering of calcium ion GO:0051282 41 0.071
positive regulation of release of sequestered calcium ion into cytosol GO:0051281 16 0.070
granulocyte migration GO:0097530 40 0.069
negative regulation of biomineral tissue development GO:0070168 8 0.069
cellular response to dna damage stimulus GO:0006974 379 0.068
protein targeting GO:0006605 187 0.068
extrinsic apoptotic signaling pathway GO:0097191 119 0.068
cell type specific apoptotic process GO:0097285 125 0.068
establishment of protein localization to organelle GO:0072594 172 0.067
chemotaxis GO:0006935 157 0.067
regulation of cellular response to stress GO:0080135 244 0.067
response to alcohol GO:0097305 64 0.066
ras protein signal transduction GO:0007265 73 0.066
immune response regulating signaling pathway GO:0002764 97 0.066
Mouse
apoptotic signaling pathway GO:0097190 268 0.065
eosinophil degranulation GO:0043308 2 0.065
leukocyte activation involved in immune response GO:0002366 30 0.065
Mouse
regulation of inflammatory response GO:0050727 46 0.064
regulation of leukocyte migration GO:0002685 63 0.064
regulation of multi organism process GO:0043900 157 0.064
cell fate determination GO:0001709 3 0.064
endoplasmic reticulum to cytosol transport GO:1903513 13 0.063
regulation of cytokine secretion GO:0050707 57 0.063
calcium ion transport into cytosol GO:0060402 48 0.063
regulation of calcium ion transport GO:0051924 79 0.062
response to sterol GO:0036314 14 0.062
regulation of angiogenesis GO:0045765 92 0.061
cyclic nucleotide mediated signaling GO:0019935 26 0.061
myeloid leukocyte migration GO:0097529 62 0.060
negative regulation of cell differentiation GO:0045596 171 0.060
protein localization to nucleus GO:0034504 136 0.060
positive regulation of angiogenesis GO:0045766 51 0.060
positive regulation of myeloid cell differentiation GO:0045639 39 0.060
positive regulation of homeostatic process GO:0032846 47 0.059
nervous system development GO:0007399 293 0.059
cellular response to growth factor stimulus GO:0071363 197 0.058
cytosolic calcium ion transport GO:0060401 48 0.058
regulation of proteolysis GO:0030162 293 0.058
positive regulation of protein transport GO:0051222 135 0.058
protein secretion GO:0009306 98 0.058
protein import GO:0017038 130 0.057
cd8 positive alpha beta t cell activation GO:0036037 3 0.056
regulation of extrinsic apoptotic signaling pathway GO:2001236 85 0.056
positive regulation of stress activated mapk cascade GO:0032874 60 0.055
regulation of behavior GO:0050795 82 0.055
cellular response to lipopolysaccharide GO:0071222 57 0.055
monocyte chemotaxis GO:0002548 20 0.054
positive regulation of cell cycle process GO:0090068 106 0.054
positive regulation of stress activated protein kinase signaling cascade GO:0070304 61 0.054
regulation of t cell proliferation GO:0042129 42 0.054
single organism cellular localization GO:1902580 332 0.054
female gamete generation GO:0007292 2 0.054
regulation of camp mediated signaling GO:0043949 13 0.053
neutrophil migration GO:1990266 25 0.053
granulocyte chemotaxis GO:0071621 37 0.053
nucleocytoplasmic transport GO:0006913 176 0.053
lipid metabolic process GO:0006629 381 0.053
cell development GO:0048468 328 0.053
sarcoplasmic reticulum calcium ion transport GO:0070296 13 0.053
response to nitric oxide GO:0071731 4 0.052
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 85 0.052
growth GO:0040007 202 0.051
protein catabolic process GO:0030163 325 0.051
cellular response to abiotic stimulus GO:0071214 117 0.051
Human
receptor internalization GO:0031623 43 0.051
negative regulation of cytokine production GO:0001818 82 0.050
protein import into nucleus GO:0006606 104 0.050
regulation of jnk cascade GO:0046328 73 0.050
nuclear transport GO:0051169 179 0.050
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 109 0.050
stem cell differentiation GO:0048863 93 0.049
gtp catabolic process GO:0006184 237 0.049
jak stat cascade GO:0007259 46 0.049
regulation of viral process GO:0050792 103 0.049
regulation of cytokine production involved in immune response GO:0002718 22 0.048
purine ribonucleotide catabolic process GO:0009154 404 0.048
regulation of peptidyl tyrosine phosphorylation GO:0050730 108 0.048
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 131 0.048
regulation of protein localization GO:0032880 296 0.048
positive regulation of cd8 positive alpha beta t cell proliferation GO:2000566 1 0.048
biological adhesion GO:0022610 331 0.047
osteoblast differentiation GO:0001649 92 0.047
purine containing compound catabolic process GO:0072523 411 0.046
purine nucleoside triphosphate catabolic process GO:0009146 392 0.046
regulation of vasculature development GO:1901342 97 0.046
positive regulation of immunoglobulin mediated immune response GO:0002891 4 0.046
multicellular organismal aging GO:0010259 3 0.046
regulation of cell cycle process GO:0010564 266 0.045
cytokine metabolic process GO:0042107 38 0.045
regulation of monocyte chemotaxis GO:0090025 11 0.045
regulation of sensory perception GO:0051931 3 0.045
stress activated protein kinase signaling cascade GO:0031098 94 0.045
regulation of growth GO:0040008 165 0.045
response to interleukin 15 GO:0070672 6 0.045
negative regulation of sequestering of calcium ion GO:0051283 41 0.045
response to tumor necrosis factor GO:0034612 76 0.045
regulation of release of sequestered calcium ion into cytosol GO:0051279 27 0.044
protein processing GO:0016485 226 0.044
locomotory behavior GO:0007626 1 0.044
ribonucleoside triphosphate metabolic process GO:0009199 412 0.044
viral life cycle GO:0019058 132 0.044
positive regulation of jnk cascade GO:0046330 52 0.043
neurogenesis GO:0022008 169 0.043
regulation of protein serine threonine kinase activity GO:0071900 179 0.043
cardiovascular system development GO:0072358 262 0.043
jnk cascade GO:0007254 80 0.043
mitotic cell cycle GO:0000278 326 0.043
guanosine containing compound catabolic process GO:1901069 239 0.043
cellular response to molecule of bacterial origin GO:0071219 62 0.043
positive regulation of cyclic nucleotide metabolic process GO:0030801 49 0.043
regulation of cell division GO:0051302 116 0.042
positive regulation of catabolic process GO:0009896 310 0.042
regulation of cytokine biosynthetic process GO:0042035 35 0.042
regulation of cd4 positive alpha beta t cell proliferation GO:2000561 2 0.042
cell adhesion GO:0007155 325 0.042
response to growth factor GO:0070848 205 0.042
negative regulation of blood vessel morphogenesis GO:2000181 41 0.042
modification of morphology or physiology of other organism GO:0035821 43 0.041
interspecies interaction between organisms GO:0044419 156 0.041
organ formation GO:0048645 3 0.041
cytokine production involved in immune response GO:0002367 27 0.041
negative regulation of leukocyte differentiation GO:1902106 24 0.041
regulation of peptidase activity GO:0052547 180 0.041
viral process GO:0016032 146 0.040
protein localization to organelle GO:0033365 280 0.040
stress activated mapk cascade GO:0051403 93 0.040
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.040
positive regulation of map kinase activity GO:0043406 80 0.040
regulation of cell adhesion GO:0030155 166 0.040
nucleoside triphosphate metabolic process GO:0009141 422 0.040
cell division GO:0051301 168 0.040
protein maturation GO:0051604 233 0.040
forelimb morphogenesis GO:0035136 4 0.040
carbohydrate derivative biosynthetic process GO:1901137 207 0.039
response to nitrogen compound GO:1901698 184 0.039
oogenesis GO:0048477 2 0.039
regulation of adaptive immune response GO:0002819 33 0.039
Human
regulation of protein secretion GO:0050708 86 0.039
positive regulation of lipid metabolic process GO:0045834 50 0.039
regulation of apoptotic signaling pathway GO:2001233 175 0.038
negative regulation of ossification GO:0030279 21 0.038
release of sequestered calcium ion into cytosol GO:0051209 41 0.038
activation of immune response GO:0002253 114 0.038
Mouse
positive regulation of innate immune response GO:0045089 79 0.038
Mouse
cd4 positive alpha beta t cell differentiation GO:0043367 4 0.038
Mouse
epithelial cell differentiation GO:0030855 141 0.038
sensory perception of pain GO:0019233 4 0.038
negative regulation of cytokine production involved in immune response GO:0002719 13 0.038
glial cell migration GO:0008347 4 0.038
negative regulation of cd4 positive alpha beta t cell activation GO:2000515 1 0.038
positive regulation of cell division GO:0051781 59 0.038
protein targeting to nucleus GO:0044744 104 0.038
rho protein signal transduction GO:0007266 26 0.037
chromatin organization GO:0006325 351 0.037
Mouse
cellular response to interleukin 15 GO:0071350 6 0.037
release of sequestered calcium ion into cytosol by sarcoplasmic reticulum GO:0014808 13 0.037
negative regulation of multi organism process GO:0043901 92 0.037
t cell selection GO:0045058 4 0.036
Mouse
regulation of lymphocyte mediated immunity GO:0002706 33 0.036
positive regulation of proteolysis GO:0045862 142 0.036
organ morphogenesis GO:0009887 147 0.036
negative regulation of response to external stimulus GO:0032102 83 0.036
protein acylation GO:0043543 138 0.036
Mouse
t cell differentiation in thymus GO:0033077 4 0.036
hormone secretion GO:0046879 65 0.036
regulation of small gtpase mediated signal transduction GO:0051056 156 0.036
nuclear import GO:0051170 106 0.036
positive regulation of neutrophil chemotaxis GO:0090023 7 0.036
multi organism cellular process GO:0044764 156 0.036
negative regulation of cellular component movement GO:0051271 106 0.035
nucleotide catabolic process GO:0009166 408 0.035
negative regulation of alpha beta t cell activation GO:0046636 3 0.035
immune response regulating cell surface receptor signaling pathway GO:0002768 51 0.035
determination of adult lifespan GO:0008340 2 0.035
response to hypoxia GO:0001666 96 0.035
regulation of stress activated mapk cascade GO:0032872 84 0.034
positive regulation of cytokine biosynthetic process GO:0042108 25 0.034
purine ribonucleoside metabolic process GO:0046128 437 0.034
regulation of cd8 positive alpha beta t cell activation GO:2001185 2 0.034
cell projection organization GO:0030030 252 0.034
amide transport GO:0042886 76 0.034
gtp metabolic process GO:0046039 239 0.034
negative regulation of alpha beta t cell proliferation GO:0046642 1 0.034
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.034
positive regulation of granulocyte chemotaxis GO:0071624 9 0.033
cellular component morphogenesis GO:0032989 314 0.033
actin filament organization GO:0007015 128 0.033
morphogenesis of an epithelium GO:0002009 60 0.033
regulation of hormone levels GO:0010817 125 0.033
cd4 positive alpha beta t cell differentiation involved in immune response GO:0002294 4 0.033
Mouse
regulation of hormone secretion GO:0046883 57 0.033
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 125 0.033
calcium ion transport from endoplasmic reticulum to cytosol GO:1903514 13 0.033
regulation of lipid metabolic process GO:0019216 96 0.032
regulation of stress activated protein kinase signaling cascade GO:0070302 85 0.032
regulation of protein catabolic process GO:0042176 155 0.032
mitotic cell cycle process GO:1903047 286 0.032
tyrosine phosphorylation of stat protein GO:0007260 33 0.032
regulation of ras protein signal transduction GO:0046578 155 0.032
positive regulation of production of molecular mediator of immune response GO:0002702 11 0.032
mature dendritic cell differentiation GO:0097029 2 0.031
positive regulation of defense response GO:0031349 87 0.031
Mouse
regulation of reactive oxygen species metabolic process GO:2000377 41 0.031
receptor metabolic process GO:0043112 81 0.031
response to decreased oxygen levels GO:0036293 96 0.031
regulation of protein maturation GO:1903317 150 0.031
regulation of nucleocytoplasmic transport GO:0046822 98 0.031
segmentation GO:0035282 4 0.031
regulation of cell morphogenesis GO:0022604 153 0.031
regulation of nucleoside metabolic process GO:0009118 209 0.031
negative regulation of angiogenesis GO:0016525 39 0.030
phospholipase c activating g protein coupled receptor signaling pathway GO:0007200 15 0.030
endocytosis GO:0006897 159 0.030
regulation of lymphocyte chemotaxis GO:1901623 12 0.030
negative regulation of protein modification process GO:0031400 200 0.030
regulation of tyrosine phosphorylation of stat protein GO:0042509 30 0.030
execution phase of apoptosis GO:0097194 32 0.030
regulation of jak stat cascade GO:0046425 44 0.030
macromolecule methylation GO:0043414 97 0.030
Mouse
positive regulation of organelle organization GO:0010638 195 0.030
organophosphate biosynthetic process GO:0090407 163 0.029
nucleoside phosphate catabolic process GO:1901292 412 0.029
single organism cell adhesion GO:0098602 179 0.029
cellular macromolecule catabolic process GO:0044265 380 0.029
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.029
single organism nuclear import GO:1902593 104 0.029
regulation of execution phase of apoptosis GO:1900117 11 0.029
behavior GO:0007610 112 0.029
regulation of oxidoreductase activity GO:0051341 43 0.029
ribonucleotide catabolic process GO:0009261 405 0.028
regulation of peptide transport GO:0090087 62 0.028

IRF4 disease predictions

Disease DO term ID Size Probability Func Analog Org
immune system disease DOID:2914 155 0.130
hematopoietic system disease DOID:74 100 0.049
musculoskeletal system disease DOID:17 223 0.046
connective tissue disease DOID:65 109 0.040
cancer DOID:162 167 0.031
Human
disease of cellular proliferation DOID:14566 174 0.031
Human
organ system cancer DOID:0050686 164 0.031
Human
disease by infectious agent DOID:0050117 34 0.030
bone disease DOID:0080001 88 0.030