IMP

Process View

Homo sapiens

6 genes annotated in human

response to interleukin 15

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-15 stimulus.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "response to interleukin 15"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "response to interleukin 15" (in gray)

Name	Description	Probability	Func Analog Organism
PTPN1	protein tyrosine phosphatase, non-receptor type 1	1.000	Human
INSR	insulin receptor	0.982
PIK3R1	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)	0.969
STAT5A	signal transducer and activator of transcription 5A	0.913
GHR	growth hormone receptor	0.869
CCR5	chemokine (C-C motif) receptor 5	0.825	Human
JAK2	Janus kinase 2	0.572	Human
SH2B1	SH2B adaptor protein 1	0.530
GRB10	growth factor receptor-bound protein 10	0.468
IRS1	insulin receptor substrate 1	0.357
CCL5	chemokine (C-C motif) ligand 5	0.321
SOCS3	suppressor of cytokine signaling 3	0.312
IL2RB	interleukin 2 receptor, beta	0.303
STAT5B	signal transducer and activator of transcription 5B	0.252	Mouse
STAT3	signal transducer and activator of transcription 3 (acute-phase response factor)	0.226
ZAP70	zeta-chain (TCR) associated protein kinase 70kDa	0.186
LAT	linker for activation of T cells	0.185
IFNG	interferon, gamma	0.109
GRB2	growth factor receptor-bound protein 2	0.107
IFNGR1	interferon gamma receptor 1	0.098
CCR7	chemokine (C-C motif) receptor 7	0.081	Human
CCL22	chemokine (C-C motif) ligand 22	0.074
CXCR6	chemokine (C-X-C motif) receptor 6	0.071	Human
PLCG1	phospholipase C, gamma 1	0.066	Human
SOCS1	suppressor of cytokine signaling 1	0.048
CD40LG	CD40 ligand	0.047
IRF4	interferon regulatory factor 4	0.045
CD3E	CD3e molecule, epsilon (CD3-TCR complex)	0.041
IRS2	insulin receptor substrate 2	0.035
LTA	lymphotoxin alpha (TNF superfamily, member 1)	0.034
EPOR	erythropoietin receptor	0.034
ERBB2	v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)	0.034
CCR4	chemokine (C-C motif) receptor 4	0.032	Human
SRC	v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)	0.031
PTPN3	protein tyrosine phosphatase, non-receptor type 3	0.029
PTPN11	protein tyrosine phosphatase, non-receptor type 11	0.028
CXCR3	chemokine (C-X-C motif) receptor 3	0.027	Human
IFNAR1	interferon (alpha, beta and omega) receptor 1	0.026
SH3BP2	SH3-domain binding protein 2	0.024
IFNAR2	interferon (alpha, beta and omega) receptor 2	0.017
PTPRB	protein tyrosine phosphatase, receptor type, B	0.017
CCL4	chemokine (C-C motif) ligand 4	0.015
JAK1	Janus kinase 1	0.015
CXCL13	chemokine (C-X-C motif) ligand 13	0.015
CXCL9	chemokine (C-X-C motif) ligand 9	0.015
PTPRJ	protein tyrosine phosphatase, receptor type, J	0.014
CXCR4	chemokine (C-X-C motif) receptor 4	0.013	Human
PTPN2	protein tyrosine phosphatase, non-receptor type 2	0.013
TIRAP	toll-interleukin 1 receptor (TIR) domain containing adaptor protein	0.013
CCR2	chemokine (C-C motif) receptor 2	0.013	Human
CD247	CD247 molecule	0.012
CD74	CD74 molecule, major histocompatibility complex, class II invariant chain	0.012
CD80	CD80 molecule	0.012
NTRK1	neurotrophic tyrosine kinase, receptor, type 1	0.011
ENPP1	ectonucleotide pyrophosphatase/phosphodiesterase 1	0.011
CAPN1	calpain 1, (mu/I) large subunit	0.011
PTPN6	protein tyrosine phosphatase, non-receptor type 6	0.010