Homo sapiens

387 known processes

PARK2

parkinson protein 2, E3 ubiquitin protein ligase (parkin)

(Aliases: PRKN,LPRS2,AR-JP,PDJ)

PARK2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cation transport GO:0006812 331 0.601
Mouse
positive regulation of synaptic transmission GO:0050806 4 0.397
myeloid cell differentiation GO:0030099 117 0.389
apoptotic signaling pathway GO:0097190 268 0.370
positive regulation of cell death GO:0010942 263 0.353
Mouse
regulation of oxidative stress induced neuron death GO:1903203 9 0.352
modification dependent macromolecule catabolic process GO:0043632 212 0.319
positive regulation of cellular amine metabolic process GO:0033240 7 0.312
positive regulation of phosphorylation GO:0042327 394 0.296
mitotic cell cycle GO:0000278 326 0.293
cellular response to oxygen containing compound GO:1901701 276 0.280
cellular amine metabolic process GO:0044106 41 0.277
apoptotic mitochondrial changes GO:0008637 57 0.275
regulation of secretion GO:0051046 194 0.267
regulation of amine transport GO:0051952 5 0.243
membrane organization GO:0061024 292 0.242
secretion GO:0046903 254 0.240
regulation of ion transport GO:0043269 189 0.237
regulation of oxidative stress induced cell death GO:1903201 24 0.237
neuron death in response to oxidative stress GO:0036475 9 0.222
post embryonic development GO:0009791 2 0.220
intrinsic apoptotic signaling pathway in response to oxidative stress GO:0008631 21 0.218
regulation of reactive oxygen species metabolic process GO:2000377 41 0.216
regulation of secretion by cell GO:1903530 177 0.214
cell projection organization GO:0030030 252 0.210
vesicle mediated transport GO:0016192 371 0.200
organophosphate catabolic process GO:0046434 430 0.199
metal ion transport GO:0030001 272 0.198
locomotory behavior GO:0007626 1 0.187
Mouse Fly
erythrocyte homeostasis GO:0034101 31 0.185
carbohydrate metabolic process GO:0005975 207 0.182
negative regulation of phosphorus metabolic process GO:0010563 267 0.179
divalent metal ion transport GO:0070838 152 0.178
enzyme linked receptor protein signaling pathway GO:0007167 303 0.167
single organism carbohydrate metabolic process GO:0044723 193 0.166
calcium ion homeostasis GO:0055074 122 0.159
cellular protein catabolic process GO:0044257 261 0.158
negative regulation of kinase activity GO:0033673 106 0.155
single organism membrane fusion GO:0044801 37 0.155
dephosphorylation GO:0016311 209 0.153
negative regulation of protein phosphorylation GO:0001933 140 0.149
dopamine transport GO:0015872 5 0.147
Mouse
cell morphogenesis GO:0000902 296 0.143
cation transmembrane transport GO:0098655 238 0.141
regulation of synaptic transmission dopaminergic GO:0032225 4 0.137
regulation of cellular amino acid metabolic process GO:0006521 6 0.135
microtubule cytoskeleton organization GO:0000226 176 0.134
response to oxygen containing compound GO:1901700 369 0.134
regulation of neurotransmitter secretion GO:0046928 3 0.130
Mouse
neuron differentiation GO:0030182 138 0.127
response to abiotic stimulus GO:0009628 336 0.126
erythrocyte differentiation GO:0030218 28 0.126
negative regulation of intracellular signal transduction GO:1902532 183 0.125
actin filament based process GO:0030029 224 0.125
protein modification by small protein conjugation GO:0032446 342 0.124
regulation of membrane potential GO:0042391 95 0.124
amine metabolic process GO:0009308 44 0.124
positive regulation of programmed cell death GO:0043068 249 0.123
Mouse
peptidyl serine modification GO:0018209 106 0.123
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.122
catecholamine secretion GO:0050432 1 0.120
regulation of cellular response to oxidative stress GO:1900407 26 0.120
regulation of cellular ketone metabolic process GO:0010565 50 0.119
neuron development GO:0048666 113 0.117
ion transmembrane transport GO:0034220 338 0.116
negative regulation of cellular protein metabolic process GO:0032269 353 0.115
calcium ion transport GO:0006816 147 0.112
peptidyl serine phosphorylation GO:0018105 101 0.111
biological adhesion GO:0022610 331 0.111
regulation of neuron death GO:1901214 56 0.109
mitochondrion organization GO:0007005 156 0.109
cellular calcium ion homeostasis GO:0006874 117 0.108
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.106
developmental programmed cell death GO:0010623 3 0.106
purine nucleotide catabolic process GO:0006195 405 0.104
regulation of cell adhesion GO:0030155 166 0.103
negative regulation of reactive oxygen species metabolic process GO:2000378 11 0.102
associative learning GO:0008306 1 0.102
cellular lipid metabolic process GO:0044255 303 0.101
sequestering of calcium ion GO:0051208 17 0.100
hemostasis GO:0007599 76 0.100
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.098
regulation of microtubule cytoskeleton organization GO:0070507 61 0.098
inorganic cation transmembrane transport GO:0098662 194 0.097
regulation of protein kinase activity GO:0045859 289 0.097
regulation of response to oxidative stress GO:1902882 26 0.096
purine ribonucleoside metabolic process GO:0046128 437 0.096
secretion by cell GO:0032940 226 0.095
sulfur compound metabolic process GO:0006790 101 0.094
cellular component morphogenesis GO:0032989 314 0.093
metal ion homeostasis GO:0055065 169 0.092
Fly
cell death in response to oxidative stress GO:0036473 29 0.091
oxidation reduction process GO:0055114 396 0.090
regulation of cell projection organization GO:0031344 107 0.090
response to endoplasmic reticulum stress GO:0034976 49 0.090
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 131 0.089
positive regulation of transport GO:0051050 336 0.089
purine containing compound catabolic process GO:0072523 411 0.088
cellular divalent inorganic cation homeostasis GO:0072503 128 0.087
organelle fusion GO:0048284 36 0.084
hematopoietic or lymphoid organ development GO:0048534 186 0.084
rho protein signal transduction GO:0007266 26 0.084
posttranscriptional regulation of gene expression GO:0010608 213 0.083
cytosolic calcium ion homeostasis GO:0051480 89 0.083
modification dependent protein catabolic process GO:0019941 209 0.082
axon development GO:0061564 34 0.082
negative regulation of cell death GO:0060548 345 0.082
cellular response to decreased oxygen levels GO:0036294 51 0.082
positive regulation of cellular component organization GO:0051130 376 0.081
regulation of neuronal synaptic plasticity GO:0048168 1 0.080
positive regulation of amine transport GO:0051954 2 0.079
positive regulation of ion transport GO:0043270 87 0.078
system process GO:0003008 349 0.078
Mouse
ribonucleoside triphosphate catabolic process GO:0009203 391 0.077
cellular chemical homeostasis GO:0055082 180 0.077
protein localization to membrane GO:0072657 160 0.076
single organismal cell cell adhesion GO:0016337 148 0.076
female gamete generation GO:0007292 2 0.075
Fly
sulfur compound biosynthetic process GO:0044272 38 0.074
cellular macromolecule catabolic process GO:0044265 380 0.074
small gtpase mediated signal transduction GO:0007264 78 0.073
regulation of microtubule polymerization GO:0031113 12 0.073
signal transduction by phosphorylation GO:0023014 297 0.073
Fly
regulation of cellular amine metabolic process GO:0033238 11 0.072
single organism cell adhesion GO:0098602 179 0.072
regulation of calcium ion transport GO:0051924 79 0.071
blood coagulation GO:0007596 76 0.071
positive regulation of secretion GO:0051047 116 0.070
nucleoside triphosphate catabolic process GO:0009143 394 0.070
microtubule polymerization GO:0046785 18 0.070
regulation of kinase activity GO:0043549 314 0.069
inorganic ion transmembrane transport GO:0098660 231 0.069
cellular carbohydrate metabolic process GO:0044262 84 0.068
cell adhesion GO:0007155 325 0.068
regulation of cellular component biogenesis GO:0044087 281 0.068
negative regulation of protein modification process GO:0031400 200 0.067
regulation of intrinsic apoptotic signaling pathway GO:2001242 72 0.067
synaptic transmission GO:0007268 61 0.066
Mouse
regulation of catecholamine secretion GO:0050433 1 0.065
cellular metal ion homeostasis GO:0006875 146 0.064
chemical homeostasis GO:0048878 306 0.064
Fly
chromatin organization GO:0006325 351 0.064
ribonucleoside triphosphate metabolic process GO:0009199 412 0.064
cellular amino acid metabolic process GO:0006520 116 0.063
ribonucleotide catabolic process GO:0009261 405 0.062
response to inorganic substance GO:0010035 127 0.061
negative regulation of phosphorylation GO:0042326 174 0.061
negative regulation of transferase activity GO:0051348 124 0.060
positive regulation of organelle organization GO:0010638 195 0.060
positive regulation of gtp catabolic process GO:0033126 166 0.060
divalent inorganic cation transport GO:0072511 158 0.060
cellular response to oxidative stress GO:0034599 85 0.059
compound eye development GO:0048749 1 0.059
actin cytoskeleton organization GO:0030036 207 0.059
cation homeostasis GO:0055080 189 0.058
Fly
regulation of hydrogen peroxide mediated programmed cell death GO:1901298 4 0.057
mitochondrial transport GO:0006839 60 0.057
regulation of cellular response to stress GO:0080135 244 0.057
cellular homeostasis GO:0019725 196 0.057
Fly
positive regulation of apoptotic process GO:0043065 246 0.057
Mouse
negative regulation of phosphate metabolic process GO:0045936 267 0.057
immune response activating cell surface receptor signaling pathway GO:0002429 45 0.056
negative regulation of response to oxidative stress GO:1902883 18 0.056
mapk cascade GO:0000165 288 0.056
Fly
regulation of cell cycle GO:0051726 393 0.056
negative regulation of catalytic activity GO:0043086 335 0.056
regulation of nervous system development GO:0051960 88 0.056
negative regulation of protein kinase activity GO:0006469 98 0.055
organic hydroxy compound metabolic process GO:1901615 147 0.054
Mouse
hydrogen peroxide mediated programmed cell death GO:0010421 4 0.054
response to organic cyclic compound GO:0014070 204 0.054
ras protein signal transduction GO:0007265 73 0.054
regulation of apoptotic signaling pathway GO:2001233 175 0.054
taxis GO:0042330 157 0.054
regulation of intracellular transport GO:0032386 195 0.053
ubiquitin dependent protein catabolic process GO:0006511 206 0.053
single organism membrane organization GO:0044802 268 0.053
protein dephosphorylation GO:0006470 81 0.052
regulation of cytoskeleton organization GO:0051493 177 0.052
response to organonitrogen compound GO:0010243 156 0.051
cell part morphogenesis GO:0032990 137 0.051
guanosine containing compound metabolic process GO:1901068 244 0.051
mitotic cell cycle phase transition GO:0044772 162 0.051
regulation of metal ion transport GO:0010959 120 0.051
maintenance of location GO:0051235 112 0.050
cell growth GO:0016049 160 0.050
positive regulation of cell development GO:0010720 92 0.050
calcium ion transmembrane transport GO:0070588 76 0.050
negative regulation of platelet aggregation GO:0090331 3 0.050
axon extension involved in axon guidance GO:0048846 5 0.050
regulation of coagulation GO:0050818 44 0.050
regulation of translation GO:0006417 89 0.050
membrane fusion GO:0061025 43 0.049
cell cycle phase transition GO:0044770 173 0.049
negative regulation of hydrogen peroxide mediated programmed cell death GO:1901299 3 0.049
cellular ion homeostasis GO:0006873 168 0.049
regulation of mitotic cell cycle GO:0007346 189 0.049
regulation of cell cycle process GO:0010564 266 0.049
regulation of muscle system process GO:0090257 53 0.049
nucleoside triphosphate metabolic process GO:0009141 422 0.048
cellular response to organic cyclic compound GO:0071407 127 0.048
neuromuscular junction development GO:0007528 3 0.048
positive regulation of cell projection organization GO:0031346 64 0.048
cell projection assembly GO:0030031 126 0.048
ribonucleoside catabolic process GO:0042454 406 0.048
lipid metabolic process GO:0006629 381 0.047
erk1 and erk2 cascade GO:0070371 104 0.047
regulation of nucleotide catabolic process GO:0030811 205 0.046
nervous system development GO:0007399 293 0.046
generation of neurons GO:0048699 152 0.046
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.046
ion homeostasis GO:0050801 230 0.045
Fly
response to hypoxia GO:0001666 96 0.045
glycosyl compound catabolic process GO:1901658 413 0.045
regulation of ras protein signal transduction GO:0046578 155 0.045
cdc42 protein signal transduction GO:0032488 4 0.044
positive regulation of protein phosphorylation GO:0001934 313 0.044
cytoplasmic transport GO:0016482 379 0.044
regulation of mitosis GO:0007088 63 0.044
epithelial cell differentiation GO:0030855 141 0.043
dopaminergic neuron differentiation GO:0071542 1 0.043
regulation of oxidative stress induced neuron intrinsic apoptotic signaling pathway GO:1903376 7 0.043
positive regulation of peptidyl serine phosphorylation GO:0033138 42 0.043
generation of precursor metabolites and energy GO:0006091 68 0.043
cellular ketone metabolic process GO:0042180 80 0.042
i kappab kinase nf kappab signaling GO:0007249 166 0.042
negative regulation of cell cycle GO:0045786 193 0.042
intrinsic apoptotic signaling pathway GO:0097193 127 0.042
negative regulation of programmed cell death GO:0043069 321 0.042
cell activation GO:0001775 213 0.042
regulation of vascular endothelial growth factor signaling pathway GO:1900746 6 0.042
immune system development GO:0002520 195 0.041
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.041
positive regulation of axon extension GO:0045773 4 0.041
sequestering of metal ion GO:0051238 24 0.041
hemopoiesis GO:0030097 180 0.041
multicellular organismal response to stress GO:0033555 1 0.041
chemotaxis GO:0006935 157 0.041
cellular macromolecular complex assembly GO:0034622 324 0.041
purine nucleoside monophosphate metabolic process GO:0009126 186 0.041
cell development GO:0048468 328 0.040
Fly
endomembrane system organization GO:0010256 196 0.040
regulation of transferase activity GO:0051338 355 0.040
mitotic cell cycle process GO:1903047 286 0.040
epidermis development GO:0008544 59 0.040
platelet activation GO:0030168 44 0.040
gtp catabolic process GO:0006184 237 0.039
regulation of peptidyl serine phosphorylation GO:0033135 50 0.039
neurological system process GO:0050877 163 0.039
Mouse
regulation of synaptic plasticity GO:0048167 3 0.039
cellular response to dna damage stimulus GO:0006974 379 0.039
memory GO:0007613 3 0.039
negative regulation of oxidative stress induced cell death GO:1903202 17 0.039
negative regulation of apoptotic signaling pathway GO:2001234 97 0.039
reactive oxygen species metabolic process GO:0072593 75 0.037
muscle system process GO:0003012 81 0.037
oocyte development GO:0048599 1 0.037
purine nucleoside catabolic process GO:0006152 398 0.037
regulation of microtubule based process GO:0032886 74 0.037
transmembrane transport GO:0055085 399 0.037
erythrocyte development GO:0048821 3 0.037
hydrogen peroxide metabolic process GO:0042743 20 0.037
regulation of cellular response to growth factor stimulus GO:0090287 76 0.036
positive regulation of nucleotide catabolic process GO:0030813 185 0.036
negative regulation of apoptotic process GO:0043066 316 0.036
negative regulation of cellular response to oxidative stress GO:1900408 18 0.036
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.036
mitotic nuclear division GO:0007067 119 0.036
neuron intrinsic apoptotic signaling pathway in response to oxidative stress GO:0036480 7 0.036
catecholamine transport GO:0051937 6 0.036
Mouse
chondroitin sulfate proteoglycan biosynthetic process GO:0050650 10 0.036
response to cytokine GO:0034097 232 0.036
regulation of protein localization GO:0032880 296 0.036
regulation of nuclear division GO:0051783 65 0.035
regulation of response to wounding GO:1903034 101 0.035
embryo development GO:0009790 123 0.035
reactive oxygen species biosynthetic process GO:1903409 4 0.035
positive regulation of catecholamine secretion GO:0033605 1 0.035
oogenesis GO:0048477 2 0.034
Fly
purine ribonucleotide catabolic process GO:0009154 404 0.034
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.034
purine nucleoside triphosphate catabolic process GO:0009146 392 0.034
neuron apoptotic process GO:0051402 39 0.034
protein localization to organelle GO:0033365 280 0.034
Mouse
regulation of actin filament based process GO:0032970 141 0.033
mast cell degranulation GO:0043303 4 0.033
cellular response to organonitrogen compound GO:0071417 124 0.033
guanosine containing compound catabolic process GO:1901069 239 0.033
purine ribonucleoside catabolic process GO:0046130 398 0.033
peptidyl tyrosine modification GO:0018212 170 0.033
positive regulation of translation GO:0045727 35 0.032
histone modification GO:0016570 251 0.032
protein localization to plasma membrane GO:0072659 93 0.032
nucleoside phosphate catabolic process GO:1901292 412 0.032
regulation of cellular component size GO:0032535 82 0.032
regulation of protein complex assembly GO:0043254 147 0.032
negative regulation of multicellular organismal process GO:0051241 317 0.032
regulation of cell projection assembly GO:0060491 47 0.032
negative regulation of cellular amine metabolic process GO:0033239 3 0.032
regulation of nucleotide metabolic process GO:0006140 269 0.032
muscle adaptation GO:0043500 12 0.031
regulation of dephosphorylation GO:0035303 96 0.031
neuron death GO:0070997 65 0.031
regulation of cytoplasmic transport GO:1903649 149 0.031
cellular response to hypoxia GO:0071456 51 0.031
response to oxidative stress GO:0006979 121 0.031
startle response GO:0001964 3 0.031
Mouse
regulation of anatomical structure size GO:0090066 101 0.031
homeostasis of number of cells GO:0048872 40 0.031
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.031
response to decreased oxygen levels GO:0036293 96 0.031
divalent inorganic cation homeostasis GO:0072507 136 0.030
Fly
chromatin modification GO:0016568 298 0.030
regulation of mitochondrial membrane potential GO:0051881 23 0.030
g protein coupled receptor signaling pathway GO:0007186 207 0.030
positive regulation of developmental process GO:0051094 314 0.030
positive regulation of cytosolic calcium ion concentration GO:0007204 82 0.029
positive regulation of neurogenesis GO:0050769 49 0.029
growth GO:0040007 202 0.029
protein ubiquitination involved in ubiquitin dependent protein catabolic process GO:0042787 37 0.029
positive regulation of immune system process GO:0002684 283 0.029
negative regulation of protein metabolic process GO:0051248 391 0.029
regulation of vesicle mediated transport GO:0060627 130 0.028
circadian behavior GO:0048512 2 0.028
nitrogen compound transport GO:0071705 191 0.028
negative regulation of oxidative stress induced neuron death GO:1903204 7 0.028
positive regulation of release of cytochrome c from mitochondria GO:0090200 18 0.028
single organism reproductive process GO:0044702 98 0.028
Fly
actin filament based movement GO:0030048 17 0.028
regulation of small gtpase mediated signal transduction GO:0051056 156 0.028
limbic system development GO:0021761 3 0.028
cellular response to starvation GO:0009267 58 0.028
defense response GO:0006952 315 0.027
rhythmic behavior GO:0007622 2 0.027
innate immune response GO:0045087 178 0.027
cellular response to growth factor stimulus GO:0071363 197 0.027
cellular response to endogenous stimulus GO:0071495 336 0.027
cellular response to lipid GO:0071396 127 0.027
regulation of microtubule polymerization or depolymerization GO:0031110 27 0.027
regulation of cell division GO:0051302 116 0.027
regulation of wound healing GO:0061041 56 0.027
purine nucleoside triphosphate metabolic process GO:0009144 412 0.027
receptor mediated endocytosis GO:0006898 84 0.027
cell projection morphogenesis GO:0048858 129 0.026
peptidyl lysine modification GO:0018205 144 0.026
regulation of lipid metabolic process GO:0019216 96 0.026
regulation of establishment of protein localization GO:0070201 242 0.026
regulation of purine nucleotide metabolic process GO:1900542 264 0.026
g1 s transition of mitotic cell cycle GO:0000082 78 0.026
regulation of cytokine production GO:0001817 232 0.026
regulation of purine nucleotide catabolic process GO:0033121 205 0.026
action potential GO:0001508 34 0.026
antigen receptor mediated signaling pathway GO:0050851 38 0.026
neurotransmitter secretion GO:0007269 4 0.026
Mouse
myeloid cell homeostasis GO:0002262 34 0.025
single organism cellular localization GO:1902580 332 0.025
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.025
regulation of body fluid levels GO:0050878 99 0.025
negative regulation of hemostasis GO:1900047 22 0.025
nuclear division GO:0000280 128 0.025
phospholipid metabolic process GO:0006644 99 0.025
semicircular canal development GO:0060872 1 0.025
regulation of oxidative stress induced intrinsic apoptotic signaling pathway GO:1902175 16 0.025
response to oxygen levels GO:0070482 100 0.025
striated muscle contraction GO:0006941 52 0.025
regulation of platelet aggregation GO:0090330 4 0.025
protein targeting GO:0006605 187 0.025
regulation of neuron differentiation GO:0045664 70 0.024
cellular response to cytokine stimulus GO:0071345 181 0.024
cardiac muscle cell contraction GO:0086003 4 0.024
positive regulation of cell proliferation GO:0008284 301 0.024
lamellipodium organization GO:0097581 30 0.024
negative regulation of neuron death GO:1901215 32 0.024
immune response regulating signaling pathway GO:0002764 97 0.024
muscle contraction GO:0006936 73 0.024
renal system development GO:0072001 63 0.024
positive regulation of organic acid transport GO:0032892 3 0.024
glycoprotein biosynthetic process GO:0009101 91 0.024
neurogenesis GO:0022008 169 0.024
cell morphogenesis involved in neuron differentiation GO:0048667 44 0.024
positive regulation of kinase activity GO:0033674 204 0.024
cell division GO:0051301 168 0.024
reactive nitrogen species metabolic process GO:2001057 3 0.023
protein polymerization GO:0051258 71 0.023
response to hormone GO:0009725 175 0.023
regulation of ion homeostasis GO:2000021 73 0.023
covalent chromatin modification GO:0016569 254 0.023
plasma membrane organization GO:0007009 115 0.023
amine transport GO:0015837 7 0.023
response to lipid GO:0033993 206 0.023
microtubule based process GO:0007017 210 0.023
positive regulation of protein complex assembly GO:0031334 86 0.022
regulation of neuron apoptotic process GO:0043523 35 0.022
cellular response to reactive oxygen species GO:0034614 50 0.022
circulatory system development GO:0072359 262 0.022
monocarboxylic acid metabolic process GO:0032787 185 0.022
protein ubiquitination GO:0016567 314 0.022
cardiac muscle contraction GO:0060048 34 0.022
synaptic transmission dopaminergic GO:0001963 5 0.022
Mouse
autophagy GO:0006914 88 0.022
nucleoside monophosphate metabolic process GO:0009123 191 0.022
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.022
endocytosis GO:0006897 159 0.022
striated muscle cell apoptotic process GO:0010658 3 0.022
peptidyl lysine acetylation GO:0018394 101 0.022
relaxation of cardiac muscle GO:0055119 5 0.021
oocyte differentiation GO:0009994 2 0.021
positive regulation of nucleoside metabolic process GO:0045979 186 0.021
mating GO:0007618 1 0.021
heart contraction GO:0060047 62 0.021
glycoprotein metabolic process GO:0009100 110 0.021
positive regulation of cellular catabolic process GO:0031331 284 0.021
cellular response to hydrogen peroxide GO:0070301 37 0.021
regulation of muscle hypertrophy GO:0014743 10 0.021
sensory organ development GO:0007423 52 0.020
establishment of protein localization to membrane GO:0090150 121 0.020
cell matrix adhesion GO:0007160 85 0.020
developmental cell growth GO:0048588 18 0.020
developmental process involved in reproduction GO:0003006 66 0.020
Fly
cardiac muscle hypertrophy GO:0003300 14 0.020
epidermal cell differentiation GO:0009913 45 0.020
organic acid transport GO:0015849 65 0.020
histone acetylation GO:0016573 93 0.020
carbohydrate biosynthetic process GO:0016051 42 0.020
immune response regulating cell surface receptor signaling pathway GO:0002768 51 0.020
regulation of gtp catabolic process GO:0033124 180 0.020
regulation of response to reactive oxygen species GO:1901031 12 0.020
positive regulation of immune response GO:0050778 159 0.020
gtp metabolic process GO:0046039 239 0.020
sensory perception GO:0007600 103 0.020
negative regulation of mitochondrion organization GO:0010823 22 0.020
regulation of cell substrate adhesion GO:0010810 68 0.020
protein catabolic process GO:0030163 325 0.020
regulation of ion transmembrane transport GO:0034765 132 0.020
neuron projection development GO:0031175 106 0.020
cellular response to hormone stimulus GO:0032870 125 0.020
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.020
regulation of cell motility GO:2000145 299 0.020
negative regulation of organelle organization GO:0010639 126 0.020
organic anion transport GO:0015711 103 0.020
negative regulation of homotypic cell cell adhesion GO:0034111 3 0.020
blastoderm segmentation GO:0007350 2 0.020
regulation of reactive oxygen species biosynthetic process GO:1903426 3 0.020
regulation of growth GO:0040008 165 0.020
multicellular organismal aging GO:0010259 3 0.019
regulation of calcium ion transport into cytosol GO:0010522 33 0.019
regulation of proteasomal protein catabolic process GO:0061136 87 0.019
regulation of cellular response to vascular endothelial growth factor stimulus GO:1902547 7 0.019
energy derivation by oxidation of organic compounds GO:0015980 43 0.019
positive regulation of secretion by cell GO:1903532 108 0.019
negative regulation of cellular component organization GO:0051129 235 0.019
regulation of cell matrix adhesion GO:0001952 42 0.019
programmed cell death in response to reactive oxygen species GO:0097468 4 0.019
response to wounding GO:0009611 168 0.019
cytosolic calcium ion transport GO:0060401 48 0.019
segmentation GO:0035282 4 0.019
cofactor metabolic process GO:0051186 87 0.019
negative regulation of hydrogen peroxide induced cell death GO:1903206 9 0.019
internal protein amino acid acetylation GO:0006475 101 0.019
regulation of anatomical structure morphogenesis GO:0022603 286 0.018
regulation of transmembrane transporter activity GO:0022898 74 0.018
regulation of lamellipodium assembly GO:0010591 14 0.018
atp metabolic process GO:0046034 176 0.018
positive regulation of mapk cascade GO:0043410 190 0.018
regulation of vasculature development GO:1901342 97 0.018
positive regulation of nf kappab transcription factor activity GO:0051092 81 0.018
cellular response to macrophage colony stimulating factor stimulus GO:0036006 4 0.018
negative regulation of hydrolase activity GO:0051346 182 0.018
ribonucleoside monophosphate metabolic process GO:0009161 187 0.018
cellular cation homeostasis GO:0030003 163 0.018
axon guidance GO:0007411 12 0.018
regulation of cell cycle phase transition GO:1901987 126 0.018
cellular polysaccharide metabolic process GO:0044264 27 0.018
regulation of mast cell activation involved in immune response GO:0033006 3 0.018
positive regulation of hydrolase activity GO:0051345 331 0.018
exocytosis GO:0006887 71 0.018
intracellular protein transport GO:0006886 270 0.018
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.018
regulation of multi organism process GO:0043900 157 0.018
regulation of cardiac muscle cell apoptotic process GO:0010665 3 0.018
nucleotide catabolic process GO:0009166 408 0.018
release of sequestered calcium ion into cytosol GO:0051209 41 0.018
positive regulation of cellular component biogenesis GO:0044089 158 0.018
negative regulation of synaptic transmission GO:0050805 2 0.018
organelle localization GO:0051640 84 0.017
cardiovascular system development GO:0072358 262 0.017
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.017

PARK2 disease predictions

Disease DO term ID Size Probability Func Analog Org
central nervous system disease DOID:331 186 0.308
neurodegenerative disease DOID:1289 102 0.308
nervous system disease DOID:863 431 0.308
parkinson s disease DOID:14330 18 0.088
synucleinopathy DOID:0050890 22 0.088
sensory system disease DOID:0050155 203 0.052
eye and adnexa disease DOID:1492 150 0.021
eye disease DOID:5614 149 0.018