IMP
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regulation of oxidative stress induced cell death
Any process that modulates the frequency, rate or extent of oxidative stress-induced cell death.
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| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| BCL2 | B-cell CLL/lymphoma 2 | 0.996 | Human | |
| BCL2L1 | BCL2-like 1 | 0.989 | Human | |
| MCL1 | myeloid cell leukemia sequence 1 (BCL2-related) | 0.979 | ||
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.965 | ||
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.928 | ||
| MAFG | v-maf musculoaponeurotic fibrosarcoma oncogene homolog G (avian) | 0.922 | ||
| TRIB3 | tribbles homolog 3 (Drosophila) | 0.914 | ||
| PRDX1 | peroxiredoxin 1 | 0.882 | ||
| BAX | BCL2-associated X protein | 0.864 | Human | |
| BCL2L11 | BCL2-like 11 (apoptosis facilitator) | 0.852 | ||
| BAK1 | BCL2-antagonist/killer 1 | 0.759 | Human | |
| KEAP1 | kelch-like ECH-associated protein 1 | 0.671 | ||
| BID | BH3 interacting domain death agonist | 0.668 | ||
| SFPQ | splicing factor proline/glutamine-rich | 0.664 | ||
| BAD | BCL2-associated agonist of cell death | 0.646 | ||
| CBL | Cas-Br-M (murine) ecotropic retroviral transforming sequence | 0.532 | ||
| VHL | von Hippel-Lindau tumor suppressor | 0.369 | ||
| PLAUR | plasminogen activator, urokinase receptor | 0.326 | ||
| FBXO7 | F-box protein 7 | 0.306 | ||
| UBQLN1 | ubiquilin 1 | 0.300 | ||
| CRKL | v-crk sarcoma virus CT10 oncogene homolog (avian)-like | 0.266 | ||
| NFE2L2 | nuclear factor (erythroid-derived 2)-like 2 | 0.256 | ||
| PARK2 | parkinson protein 2, E3 ubiquitin protein ligase (parkin) | 0.237 | ||
| MAP2K5 | mitogen-activated protein kinase kinase 5 | 0.229 | ||
| MET | met proto-oncogene (hepatocyte growth factor receptor) | 0.213 | ||
| WBP4 | WW domain binding protein 4 (formin binding protein 21) | 0.187 | ||
| KAT2B | K(lysine) acetyltransferase 2B | 0.184 | ||
| NONO | non-POU domain containing, octamer-binding | 0.169 | ||
| ARNT | aryl hydrocarbon receptor nuclear translocator | 0.168 | ||
| MAFF | v-maf musculoaponeurotic fibrosarcoma oncogene homolog F (avian) | 0.151 | ||
| PLAT | plasminogen activator, tissue | 0.148 | Human | |
| UBE3A | ubiquitin protein ligase E3A | 0.141 | ||
| ZNF746 | zinc finger protein 746 | 0.135 | ||
| PINK1 | PTEN induced putative kinase 1 | 0.128 | ||
| GAB1 | GRB2-associated binding protein 1 | 0.127 | ||
| CTSD | cathepsin D | 0.124 | ||
| EGLN1 | egl nine homolog 1 (C. elegans) | 0.123 | ||
| EGFR | epidermal growth factor receptor | 0.123 | ||
| DDIT3 | DNA-damage-inducible transcript 3 | 0.118 | ||
| PLAU | plasminogen activator, urokinase | 0.115 | Human | |
| BACH1 | BTB and CNC homology 1, basic leucine zipper transcription factor 1 | 0.109 | Human | |
| RANBP9 | RAN binding protein 9 | 0.105 | ||
| PLXNB1 | plexin B1 | 0.099 | ||
| HGF | hepatocyte growth factor (hepapoietin A; scatter factor) | 0.099 | ||
| TOP1 | topoisomerase (DNA) I | 0.099 | ||
| RNF144B | ring finger protein 144B | 0.098 | ||
| CRYAB | crystallin, alpha B | 0.087 | ||
| SIN3A | SIN3 homolog A, transcription regulator (yeast) | 0.083 | ||
| CCDC6 | coiled-coil domain containing 6 | 0.081 | ||
| ARHGEF7 | Rho guanine nucleotide exchange factor (GEF) 7 | 0.081 | ||
| CEBPG | CCAAT/enhancer binding protein (C/EBP), gamma | 0.081 | ||
| ADRBK1 | adrenergic, beta, receptor kinase 1 | 0.078 | ||
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.073 | ||
| HSPB8 | heat shock 22kDa protein 8 | 0.072 | ||
| ATP6AP1 | ATPase, H+ transporting, lysosomal accessory protein 1 | 0.070 | ||
| EGLN3 | egl nine homolog 3 (C. elegans) | 0.068 | ||
| NAMPT | nicotinamide phosphoribosyltransferase | 0.066 | ||
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 | 0.064 | ||
| NCOR2 | nuclear receptor corepressor 2 | 0.064 | ||
| SQSTM1 | sequestosome 1 | 0.063 | ||
| PRKCA | protein kinase C, alpha | 0.062 | ||
| IL8 | interleukin 8 | 0.058 | ||
| DAXX | death-domain associated protein | 0.058 | ||
| HM13 | histocompatibility (minor) 13 | 0.053 | ||
| EFTUD2 | elongation factor Tu GTP binding domain containing 2 | 0.051 | ||
| CTSL1 | cathepsin L1 | 0.049 | ||
| RNR2 | l-rRNA | 0.049 | ||
| AHR | aryl hydrocarbon receptor | 0.049 | ||
| SPRR2A | small proline-rich protein 2A | 0.047 | ||
| RAPGEF1 | Rap guanine nucleotide exchange factor (GEF) 1 | 0.045 | ||
| DYNLL1 | dynein, light chain, LC8-type 1 | 0.044 | ||
| SYK | spleen tyrosine kinase | 0.044 | ||
| ZBED1 | zinc finger, BED-type containing 1 | 0.042 | ||
| APOH | apolipoprotein H (beta-2-glycoprotein I) | 0.041 | ||
| MAP1B | microtubule-associated protein 1B | 0.040 | ||
| CDC42 | cell division cycle 42 (GTP binding protein, 25kDa) | 0.040 | ||
| HDAC1 | histone deacetylase 1 | 0.039 | ||
| MAP2K6 | mitogen-activated protein kinase kinase 6 | 0.038 | ||
| DUSP23 | dual specificity phosphatase 23 | 0.037 | ||
| BANP | BTG3 associated nuclear protein | 0.035 | ||
| HUWE1 | HECT, UBA and WWE domain containing 1 | 0.035 | ||
| CHPF | chondroitin polymerizing factor | 0.035 | ||
| PGK1 | phosphoglycerate kinase 1 | 0.033 | ||
| GSK3B | glycogen synthase kinase 3 beta | 0.032 | ||
| CDK2AP2 | cyclin-dependent kinase 2 associated protein 2 | 0.031 | ||
| CALR | calreticulin | 0.031 | ||
| CREB1 | cAMP responsive element binding protein 1 | 0.031 | ||
| CRYAA | crystallin, alpha A | 0.031 | ||
| RAB5B | RAB5B, member RAS oncogene family | 0.030 | ||
| PSPC1 | paraspeckle component 1 | 0.030 | Human | |
| OS9 | osteosarcoma amplified 9, endoplasmic reticulum lectin | 0.029 | ||
| PLD3 | phospholipase D family, member 3 | 0.029 | ||
| VDAC1 | voltage-dependent anion channel 1 | 0.029 | ||
| CTSA | cathepsin A | 0.028 | ||
| DAPK1 | death-associated protein kinase 1 | 0.028 | ||
| PAK2 | p21 protein (Cdc42/Rac)-activated kinase 2 | 0.027 | ||
| CBLB | Cas-Br-M (murine) ecotropic retroviral transforming sequence b | 0.027 | ||
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.026 | ||
| GAA | glucosidase, alpha; acid | 0.026 | ||
| VCP | valosin containing protein | 0.026 | ||
| DBN1 | drebrin 1 | 0.026 | ||
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.026 | ||
| PHF17 | PHD finger protein 17 | 0.025 | ||
| GANAB | glucosidase, alpha; neutral AB | 0.025 | ||
| MSH5 | mutS homolog 5 (E. coli) | 0.025 | ||
| CSNK1A1 | casein kinase 1, alpha 1 | 0.024 | ||
| MAX | MYC associated factor X | 0.024 | ||
| VEGFA | vascular endothelial growth factor A | 0.024 | ||
| CYLD | cylindromatosis (turban tumor syndrome) | 0.024 | ||
| DYNLT1 | dynein, light chain, Tctex-type 1 | 0.024 | ||
| RHOA | ras homolog gene family, member A | 0.023 | ||
| ABI2 | abl-interactor 2 | 0.023 | ||
| HSF1 | heat shock transcription factor 1 | 0.023 | ||
| MAFK | v-maf musculoaponeurotic fibrosarcoma oncogene homolog K (avian) | 0.022 | ||
| NFE2L1 | nuclear factor (erythroid-derived 2)-like 1 | 0.021 | Human | |
| PML | promyelocytic leukemia | 0.021 | ||
| ITCH | itchy E3 ubiquitin protein ligase homolog (mouse) | 0.021 | ||
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.021 | ||
| LAT | linker for activation of T cells | 0.021 | ||
| RGS2 | regulator of G-protein signaling 2, 24kDa | 0.021 | ||
| ZNF205 | zinc finger protein 205 | 0.021 | ||
| MEF2C | myocyte enhancer factor 2C | 0.020 | ||
| PACRG | PARK2 co-regulated | 0.020 | ||
| ORM1 | orosomucoid 1 | 0.020 | ||
| SOD1 | superoxide dismutase 1, soluble | 0.020 | ||
| PCK2 | phosphoenolpyruvate carboxykinase 2 (mitochondrial) | 0.020 | ||
| NFIL3 | nuclear factor, interleukin 3 regulated | 0.019 | ||
| FGFR1 | fibroblast growth factor receptor 1 | 0.019 | ||
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | 0.019 | ||
| NUCB1 | nucleobindin 1 | 0.019 | ||
| ARNTL | aryl hydrocarbon receptor nuclear translocator-like | 0.018 | ||
| CCNE1 | cyclin E1 | 0.018 | ||
| GHR | growth hormone receptor | 0.018 | ||
| CELSR1 | cadherin, EGF LAG seven-pass G-type receptor 1 (flamingo homolog, Drosophila) | 0.018 | ||
| DIAPH1 | diaphanous homolog 1 (Drosophila) | 0.018 | ||
| WASF1 | WAS protein family, member 1 | 0.017 | ||
| PRDX6 | peroxiredoxin 6 | 0.017 | ||
| SAT1 | spermidine/spermine N1-acetyltransferase 1 | 0.017 | ||
| SCAF8 | SR-related CTD-associated factor 8 | 0.017 | ||
| CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) | 0.017 | ||
| RAD52 | RAD52 homolog (S. cerevisiae) | 0.017 | ||
| ERO1L | ERO1-like (S. cerevisiae) | 0.016 | ||
| ZFAND5 | zinc finger, AN1-type domain 5 | 0.016 | ||
| CCL20 | chemokine (C-C motif) ligand 20 | 0.016 | ||
| ERBB2 | v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) | 0.016 | ||
| RELA | v-rel reticuloendotheliosis viral oncogene homolog A (avian) | 0.016 | ||
| POLR2C | polymerase (RNA) II (DNA directed) polypeptide C, 33kDa | 0.016 | ||
| GIT1 | G protein-coupled receptor kinase interacting ArfGAP 1 | 0.016 | ||
| TIMP2 | TIMP metallopeptidase inhibitor 2 | 0.016 | ||
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) | 0.016 | ||
| TUBA1A | tubulin, alpha 1a | 0.016 | ||
| LRP6 | low density lipoprotein receptor-related protein 6 | 0.015 | ||
| HSPB2 | heat shock 27kDa protein 2 | 0.015 | ||
| OTUD4 | OTU domain containing 4 | 0.015 | ||
| TPP1 | tripeptidyl peptidase I | 0.015 | ||
| EED | embryonic ectoderm development | 0.014 | ||
| NCKAP1 | NCK-associated protein 1 | 0.014 | ||
| BCL2L2 | BCL2-like 2 | 0.014 | Human | |
| ARHGDIA | Rho GDP dissociation inhibitor (GDI) alpha | 0.014 | ||
| SERPINF2 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2 | 0.014 | ||
| KIT | v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog | 0.014 | ||
| PSEN2 | presenilin 2 (Alzheimer disease 4) | 0.014 | ||
| GABPA | GA binding protein transcription factor, alpha subunit 60kDa | 0.014 | ||
| BCL6 | B-cell CLL/lymphoma 6 | 0.014 | ||
| WWOX | WW domain containing oxidoreductase | 0.014 | ||
| MDC1 | mediator of DNA-damage checkpoint 1 | 0.013 | ||
| PLXNB3 | plexin B3 | 0.013 | ||
| PVR | poliovirus receptor | 0.013 | ||
| STC2 | stanniocalcin 2 | 0.013 | ||
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa | 0.013 | ||
| ERBB3 | v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) | 0.013 | ||
| RLF | rearranged L-myc fusion | 0.013 | ||
| FOXO3 | forkhead box O3 | 0.013 | ||
| PDGFRA | platelet-derived growth factor receptor, alpha polypeptide | 0.013 | ||
| FMNL2 | formin-like 2 | 0.013 | ||
| HK2 | hexokinase 2 | 0.013 | ||
| FTH1 | ferritin, heavy polypeptide 1 | 0.013 | ||
| FES | feline sarcoma oncogene | 0.013 | ||
| SPRY4 | sprouty homolog 4 (Drosophila) | 0.012 | ||
| ARHGEF11 | Rho guanine nucleotide exchange factor (GEF) 11 | 0.012 | ||
| CHAC1 | ChaC, cation transport regulator homolog 1 (E. coli) | 0.012 | ||
| OSMR | oncostatin M receptor | 0.012 | ||
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | 0.012 | ||
| PRDX2 | peroxiredoxin 2 | 0.012 | ||
| LAMP1 | lysosomal-associated membrane protein 1 | 0.012 | ||
| PRDX4 | peroxiredoxin 4 | 0.012 | ||
| TSPYL4 | TSPY-like 4 | 0.012 | ||
| INHBA | inhibin, beta A | 0.011 | ||
| UBASH3A | ubiquitin associated and SH3 domain containing A | 0.011 | ||
| UBASH3B | ubiquitin associated and SH3 domain containing B | 0.011 | ||
| FBXO21 | F-box protein 21 | 0.011 | ||
| WDR83 | WD repeat domain 83 | 0.011 | ||
| CXCL2 | chemokine (C-X-C motif) ligand 2 | 0.011 | ||
| TOPORS | topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase | 0.011 | ||
| GCGR | glucagon receptor | 0.011 | ||
| TCF4 | transcription factor 4 | 0.011 | ||
| SIAH1 | seven in absentia homolog 1 (Drosophila) | 0.011 | ||
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.011 | ||
| GRN | granulin | 0.011 | ||
| CRYBB2 | crystallin, beta B2 | 0.011 | ||
| KYNU | kynureninase | 0.011 | ||
| STC1 | stanniocalcin 1 | 0.011 | ||
| CXCL3 | chemokine (C-X-C motif) ligand 3 | 0.011 | ||
| AMT | aminomethyltransferase | 0.011 | ||
| UBQLN2 | ubiquilin 2 | 0.011 | Human | |
| PPARA | peroxisome proliferator-activated receptor alpha | 0.011 | ||
| RAC1 | ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) | 0.011 | ||
| VTN | vitronectin | 0.011 | ||
| KNG1 | kininogen 1 | 0.011 | ||
| GAB2 | GRB2-associated binding protein 2 | 0.011 | ||
| HIPK2 | homeodomain interacting protein kinase 2 | 0.011 | ||
| FAS | Fas (TNF receptor superfamily, member 6) | 0.011 | ||
| AP1S1 | adaptor-related protein complex 1, sigma 1 subunit | 0.011 | ||
| FOXO1 | forkhead box O1 | 0.010 | ||
| USP7 | ubiquitin specific peptidase 7 (herpes virus-associated) | 0.010 | ||
| MED13L | mediator complex subunit 13-like | 0.010 | ||
| CEBPB | CCAAT/enhancer binding protein (C/EBP), beta | 0.010 | ||
| USMG5 | up-regulated during skeletal muscle growth 5 homolog (mouse) | 0.010 | ||
| LRRK2 | leucine-rich repeat kinase 2 | 0.010 | ||
| RND1 | Rho family GTPase 1 | 0.010 | ||
| BBS1 | Bardet-Biedl syndrome 1 | 0.010 | ||
| SIRT2 | sirtuin 2 | 0.010 | ||
| IL1B | interleukin 1, beta | 0.010 | ||
| CARS | cysteinyl-tRNA synthetase | 0.010 | ||
| MUC1 | mucin 1, cell surface associated | 0.010 |