Homo sapiens

176 known processes

EIF2B4

eukaryotic translation initiation factor 2B, subunit 4 delta, 67kDa

(Aliases: EIF2Bdelta,DKFZp586J0119,EIF2B,EIF-2B)

EIF2B4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
post embryonic development GO:0009791 2 0.812
glycosyl compound catabolic process GO:1901658 413 0.434
translation GO:0006412 132 0.420
oligodendrocyte development GO:0014003 6 0.398
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.392
ribonucleoside catabolic process GO:0042454 406 0.330
positive regulation of nucleotide catabolic process GO:0030813 185 0.302
nucleotide catabolic process GO:0009166 408 0.301
regulation of gtp catabolic process GO:0033124 180 0.279
ribonucleoside triphosphate metabolic process GO:0009199 412 0.264
nucleoside phosphate catabolic process GO:1901292 412 0.253
astrocyte differentiation GO:0048708 4 0.252
vesicle mediated transport GO:0016192 371 0.247
ovarian follicle development GO:0001541 5 0.244
purine nucleotide catabolic process GO:0006195 405 0.243
positive regulation of nucleotide metabolic process GO:0045981 230 0.225
nucleoside triphosphate catabolic process GO:0009143 394 0.220
purine ribonucleoside metabolic process GO:0046128 437 0.209
regulation of gtpase activity GO:0043087 180 0.206
guanosine containing compound metabolic process GO:1901068 244 0.201
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.194
gtp catabolic process GO:0006184 237 0.193
regulation of nucleoside metabolic process GO:0009118 209 0.192
positive regulation of gtpase activity GO:0043547 166 0.180
neuronal action potential GO:0019228 9 0.172
oligodendrocyte differentiation GO:0048709 7 0.171
regulation of purine nucleotide metabolic process GO:1900542 264 0.168
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.166
regulation of purine nucleotide catabolic process GO:0033121 205 0.162
nucleoside catabolic process GO:0009164 408 0.159
purine ribonucleoside catabolic process GO:0046130 398 0.158
regulation of membrane potential GO:0042391 95 0.153
ovulation cycle process GO:0022602 9 0.148
positive regulation of nucleoside metabolic process GO:0045979 186 0.144
positive regulation of hydrolase activity GO:0051345 331 0.139
nucleoside triphosphate metabolic process GO:0009141 422 0.132
positive regulation of gtp catabolic process GO:0033126 166 0.128
transmission of nerve impulse GO:0019226 11 0.124
purine containing compound catabolic process GO:0072523 411 0.121
receptor mediated endocytosis GO:0006898 84 0.109
endocytosis GO:0006897 159 0.106
ribonucleoprotein complex biogenesis GO:0022613 116 0.106
purine nucleoside triphosphate metabolic process GO:0009144 412 0.105
growth GO:0040007 202 0.104
cellular macromolecular complex assembly GO:0034622 324 0.102
gtp metabolic process GO:0046039 239 0.101
ribonucleoside triphosphate catabolic process GO:0009203 391 0.100
ribonucleotide catabolic process GO:0009261 405 0.096
positive regulation of cellular catabolic process GO:0031331 284 0.092
positive regulation of developmental process GO:0051094 314 0.091
nervous system development GO:0007399 293 0.090
posttranscriptional regulation of gene expression GO:0010608 213 0.089
Yeast
ncrna metabolic process GO:0034660 108 0.087
regulation of nucleotide metabolic process GO:0006140 269 0.086
regulation of nucleotide catabolic process GO:0030811 205 0.076
female gamete generation GO:0007292 2 0.074
positive regulation of catabolic process GO:0009896 310 0.069
single organism reproductive process GO:0044702 98 0.068
female gonad development GO:0008585 10 0.065
guanosine containing compound catabolic process GO:1901069 239 0.062
regulation of growth GO:0040008 165 0.057
ovulation cycle GO:0042698 9 0.056
purine ribonucleotide catabolic process GO:0009154 404 0.056
response to nitrogen compound GO:1901698 184 0.054
nucleic acid phosphodiester bond hydrolysis GO:0090305 102 0.053
cellular amino acid metabolic process GO:0006520 116 0.051
negative regulation of protein metabolic process GO:0051248 391 0.051
embryo development GO:0009790 123 0.049
neurogenesis GO:0022008 169 0.046
response to organonitrogen compound GO:0010243 156 0.046
rna processing GO:0006396 255 0.045
purine nucleoside catabolic process GO:0006152 398 0.045
response to hormone GO:0009725 175 0.042
ribonucleoside monophosphate metabolic process GO:0009161 187 0.041
response to monosaccharide GO:0034284 20 0.040
reproductive structure development GO:0048608 55 0.039
neurological system process GO:0050877 163 0.039
blastocyst development GO:0001824 3 0.037
reproductive process GO:0022414 106 0.036
reproductive system development GO:0061458 56 0.036
purine nucleoside monophosphate metabolic process GO:0009126 186 0.036
rna interference GO:0016246 4 0.036
carbohydrate derivative biosynthetic process GO:1901137 207 0.035
positive regulation of growth GO:0045927 58 0.035
cellular protein complex assembly GO:0043623 188 0.034
response to abiotic stimulus GO:0009628 336 0.033
response to peptide GO:1901652 65 0.032
cellular lipid metabolic process GO:0044255 303 0.031
reproduction GO:0000003 63 0.031
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.030
cell development GO:0048468 328 0.030
response to peptide hormone GO:0043434 61 0.030
regulation of cell cycle GO:0051726 393 0.029
rna splicing GO:0008380 131 0.029
glycoprotein biosynthetic process GO:0009101 91 0.029
negative regulation of cellular protein metabolic process GO:0032269 353 0.029
response to heat GO:0009408 21 0.028
dna repair GO:0006281 198 0.028
mitotic cell cycle GO:0000278 326 0.028
multicellular organism reproduction GO:0032504 42 0.028
regulation of cell cycle process GO:0010564 266 0.027
purine nucleoside triphosphate catabolic process GO:0009146 392 0.027
positive regulation of cellular component biogenesis GO:0044089 158 0.026
regulation of multicellular organism growth GO:0040014 8 0.026
multicellular organismal signaling GO:0035637 34 0.025
ribonucleoprotein complex assembly GO:0022618 78 0.025
translational initiation GO:0006413 48 0.025
atp metabolic process GO:0046034 176 0.023
glycerolipid metabolic process GO:0046486 107 0.023
defense response GO:0006952 315 0.023
regulation of cellular component biogenesis GO:0044087 281 0.023
organophosphate catabolic process GO:0046434 430 0.022
ribosome biogenesis GO:0042254 48 0.022
amine metabolic process GO:0009308 44 0.022
negative regulation of developmental process GO:0051093 247 0.021
axon ensheathment GO:0008366 6 0.021
regulation of cell differentiation GO:0045595 393 0.021
cell cycle phase transition GO:0044770 173 0.021
cell division GO:0051301 168 0.021
system process GO:0003008 349 0.021
mitochondrial respiratory chain complex i biogenesis GO:0097031 16 0.021
maturation of ssu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna GO:0000462 1 0.021
regulation of cellular amino acid metabolic process GO:0006521 6 0.021
ribonucleoprotein complex subunit organization GO:0071826 81 0.021
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.020
cellular amine metabolic process GO:0044106 41 0.020
oogenesis GO:0048477 2 0.020
regulation of cell division GO:0051302 116 0.020
positive regulation of developmental growth GO:0048639 16 0.020
mitotic cell cycle phase transition GO:0044772 162 0.020
response to endoplasmic reticulum stress GO:0034976 49 0.019
lipid metabolic process GO:0006629 381 0.019
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.019
single organism cellular localization GO:1902580 332 0.019
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.019
nucleoside monophosphate metabolic process GO:0009123 191 0.019
cytoplasmic transport GO:0016482 379 0.018
organelle assembly GO:0070925 176 0.018
mitotic cell cycle process GO:1903047 286 0.018
ribonucleoside monophosphate catabolic process GO:0009158 158 0.018
ncrna processing GO:0034470 83 0.018
glial cell development GO:0021782 7 0.018
secretion GO:0046903 254 0.018
multicellular organismal reproductive process GO:0048609 40 0.017
embryo development ending in birth or egg hatching GO:0009792 34 0.017
protein oligomerization GO:0051259 173 0.017
chromatin organization GO:0006325 351 0.017
cellular macromolecule catabolic process GO:0044265 380 0.017
regulation of cellular amine metabolic process GO:0033238 11 0.017
immune effector process GO:0002252 159 0.016
positive regulation of cellular component organization GO:0051130 376 0.016
single organism membrane organization GO:0044802 268 0.016
developmental growth GO:0048589 48 0.016
mitochondrial respiratory chain complex assembly GO:0033108 23 0.016
regulation of translation GO:0006417 89 0.016
Yeast
protein localization to organelle GO:0033365 280 0.015
associative learning GO:0008306 1 0.015
central nervous system development GO:0007417 123 0.015
cellular response to dna damage stimulus GO:0006974 379 0.015
nuclear division GO:0000280 128 0.015
regulation of mitotic cell cycle GO:0007346 189 0.015
rhythmic process GO:0048511 31 0.015
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.014
response to hexose GO:0009746 20 0.014
regulation of cellular ketone metabolic process GO:0010565 50 0.014
response to biotic stimulus GO:0009607 276 0.014
gonad development GO:0008406 34 0.014
atp catabolic process GO:0006200 157 0.014
divalent inorganic cation transport GO:0072511 158 0.013
ensheathment of neurons GO:0007272 6 0.013
cell morphogenesis GO:0000902 296 0.013
response to other organism GO:0051707 261 0.013
maintenance of location GO:0051235 112 0.013
protein dna complex subunit organization GO:0071824 80 0.013
response to temperature stimulus GO:0009266 22 0.013
gliogenesis GO:0042063 21 0.013
dephosphorylation GO:0016311 209 0.013
response to virus GO:0009615 126 0.013
response to oxygen containing compound GO:1901700 369 0.013
mitochondrion organization GO:0007005 156 0.012
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.012
chromosome segregation GO:0007059 114 0.012
regulation of protein localization GO:0032880 296 0.012
protein localization to membrane GO:0072657 160 0.012
regulation of meiosis GO:0040020 3 0.012
protein catabolic process GO:0030163 325 0.012
negative regulation of intracellular signal transduction GO:1902532 183 0.012
regulation of dna metabolic process GO:0051052 153 0.012
nucleoside monophosphate catabolic process GO:0009125 159 0.012
protein dephosphorylation GO:0006470 81 0.012
response to glucose GO:0009749 19 0.011
organelle fission GO:0048285 149 0.011
regulation of mitotic cell cycle phase transition GO:1901990 118 0.011
positive regulation of multicellular organism growth GO:0040018 6 0.011
negative regulation of cellular component organization GO:0051129 235 0.011
negative regulation of catalytic activity GO:0043086 335 0.011
rna splicing via transesterification reactions GO:0000375 90 0.011
negative regulation of phosphorus metabolic process GO:0010563 267 0.011
negative regulation of multicellular organismal process GO:0051241 317 0.011
reactive oxygen species metabolic process GO:0072593 75 0.011
multicellular organismal aging GO:0010259 3 0.011
biological adhesion GO:0022610 331 0.011
positive regulation of transport GO:0051050 336 0.011
glycoprotein metabolic process GO:0009100 110 0.011
establishment of protein localization to mitochondrion GO:0072655 22 0.011
protein maturation GO:0051604 233 0.011
covalent chromatin modification GO:0016569 254 0.011
blastocyst formation GO:0001825 3 0.011
cytokine production GO:0001816 247 0.010
macromolecule methylation GO:0043414 97 0.010
cellular protein catabolic process GO:0044257 261 0.010
regulation of kinase activity GO:0043549 314 0.010
response to external biotic stimulus GO:0043207 261 0.010
oocyte differentiation GO:0009994 2 0.010
cell projection organization GO:0030030 252 0.010
spermatid differentiation GO:0048515 4 0.010
eye photoreceptor cell differentiation GO:0001754 2 0.010
negative regulation of programmed cell death GO:0043069 321 0.010
negative regulation of phosphorylation GO:0042326 174 0.010
defense response to virus GO:0051607 71 0.010
protein secretion GO:0009306 98 0.010
development of primary sexual characteristics GO:0045137 35 0.010
immune response GO:0006955 307 0.010

EIF2B4 disease predictions

Disease DO term ID Size Probability Func Analog Org
sensory system disease DOID:0050155 203 0.024
eye and adnexa disease DOID:1492 150 0.024
nervous system disease DOID:863 431 0.024
eye disease DOID:5614 149 0.024
usher syndrome DOID:0050439 12 0.023
disease of metabolism DOID:0014667 295 0.012