Homo sapiens

65 known processes

EHMT2

euchromatic histone-lysine N-methyltransferase 2

(Aliases: DKFZp686H08213,KMT1C,G9A,NG36,C6orf30,FLJ35547,BAT8)

EHMT2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
post embryonic development GO:0009791 2 0.925
Fly
chromatin organization GO:0006325 351 0.759
peptidyl lysine modification GO:0018205 144 0.472
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.428
Mouse
histone lysine methylation GO:0034968 50 0.268
tube development GO:0035295 125 0.254
neural crest cell development GO:0014032 3 0.236
ameboidal type cell migration GO:0001667 135 0.206
basement membrane organization GO:0071711 3 0.186
cellular amine metabolic process GO:0044106 41 0.176
chromatin modification GO:0016568 298 0.161
regulation of hemoglobin biosynthetic process GO:0046984 1 0.154
protein acylation GO:0043543 138 0.146
regulation of cellular amine metabolic process GO:0033238 11 0.134
stem cell development GO:0048864 69 0.132
chromatin remodeling GO:0006338 55 0.128
motor neuron axon guidance GO:0008045 2 0.123
embryonic morphogenesis GO:0048598 85 0.122
regulation of embryonic development GO:0045995 20 0.115
post embryonic organ development GO:0048569 1 0.114
reactive nitrogen species metabolic process GO:2001057 3 0.114
epidermis morphogenesis GO:0048730 3 0.109
cellular amino acid metabolic process GO:0006520 116 0.107
negative regulation of protein metabolic process GO:0051248 391 0.103
hemoglobin biosynthetic process GO:0042541 3 0.101
mesenchymal cell development GO:0014031 50 0.093
chemokine c x c motif ligand 2 production GO:0072567 3 0.092
biological adhesion GO:0022610 331 0.090
negative regulation of epithelial cell migration GO:0010633 38 0.089
negative regulation of cellular amine metabolic process GO:0033239 3 0.086
cellular ketone metabolic process GO:0042180 80 0.076
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.076
regulation of chemokine c x c motif ligand 2 production GO:2000341 2 0.076
neuron projection development GO:0031175 106 0.075
Fly
embryo development GO:0009790 123 0.075
dna replication GO:0006260 116 0.074
response to growth factor GO:0070848 205 0.074
histone modification GO:0016570 251 0.072
vasodilation GO:0042311 4 0.072
glycoprotein biosynthetic process GO:0009101 91 0.072
stem cell differentiation GO:0048863 93 0.072
regulation of heterotypic cell cell adhesion GO:0034114 14 0.071
protein modification by small protein conjugation GO:0032446 342 0.069
digestive tract morphogenesis GO:0048546 56 0.066
negative regulation of cellular component movement GO:0051271 106 0.066
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 89 0.065
regulation of cellular amino acid metabolic process GO:0006521 6 0.064
regulation of cellular ketone metabolic process GO:0010565 50 0.063
negative regulation of interleukin 8 biosynthetic process GO:0045415 3 0.063
epithelium development GO:0060429 227 0.061
cell adhesion GO:0007155 325 0.060
regulation of growth GO:0040008 165 0.058
mitotic cell cycle GO:0000278 326 0.055
cellular response to growth factor stimulus GO:0071363 197 0.054
cell migration involved in sprouting angiogenesis GO:0002042 19 0.054
mesenchyme development GO:0060485 59 0.053
regulation of dna metabolic process GO:0051052 153 0.053
protein acetylation GO:0006473 116 0.052
regulation of cell growth GO:0001558 135 0.052
reactive oxygen species biosynthetic process GO:1903409 4 0.052
glycosylation GO:0070085 71 0.051
cellular response to fluid shear stress GO:0071498 7 0.051
hemoglobin metabolic process GO:0020027 3 0.050
oxidation reduction process GO:0055114 396 0.049
protein oligomerization GO:0051259 173 0.049
amine metabolic process GO:0009308 44 0.048
digestive system development GO:0055123 75 0.048
regulation of reactive oxygen species biosynthetic process GO:1903426 3 0.048
cellular response to laminar fluid shear stress GO:0071499 5 0.047
small gtpase mediated signal transduction GO:0007264 78 0.047
negative regulation of catalytic activity GO:0043086 335 0.045
nucleosome organization GO:0034728 66 0.045
cellular macromolecular complex assembly GO:0034622 324 0.044
regulation of protein processing GO:0070613 150 0.044
regulation of chemokine production GO:0032642 31 0.043
mesenchymal cell differentiation GO:0048762 52 0.043
reactive oxygen species metabolic process GO:0072593 75 0.042
nucleosome assembly GO:0006334 50 0.042
single organism carbohydrate metabolic process GO:0044723 193 0.042
regulation of reactive oxygen species metabolic process GO:2000377 41 0.041
circulatory system process GO:0003013 113 0.041
protein alkylation GO:0008213 74 0.041
macromolecule methylation GO:0043414 97 0.041
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.041
negative regulation of nf kappab transcription factor activity GO:0032088 51 0.041
regulation of gene expression epigenetic GO:0040029 73 0.040
Mouse Rat
carbohydrate metabolic process GO:0005975 207 0.040
chemokine production GO:0032602 32 0.040
regulation of peptidase activity GO:0052547 180 0.040
negative regulation of protein processing GO:0010955 142 0.038
covalent chromatin modification GO:0016569 254 0.038
neural crest cell migration GO:0001755 2 0.038
methylation dependent chromatin silencing GO:0006346 3 0.038
regulation of endopeptidase activity GO:0052548 170 0.038
epithelial cell differentiation GO:0030855 141 0.038
neuron apoptotic process GO:0051402 39 0.037
protein methylation GO:0006479 74 0.037
dna methylation or demethylation GO:0044728 19 0.037
Mouse Rat
carbohydrate derivative biosynthetic process GO:1901137 207 0.037
cellular response to endogenous stimulus GO:0071495 336 0.036
modification dependent macromolecule catabolic process GO:0043632 212 0.036
circulatory system development GO:0072359 262 0.036
regulation of anatomical structure morphogenesis GO:0022603 286 0.036
Fly
dna replication independent nucleosome assembly GO:0006336 27 0.036
negative regulation of response to cytokine stimulus GO:0060761 25 0.035
protein glycosylation GO:0006486 62 0.035
positive regulation of developmental process GO:0051094 314 0.035
Fly
vesicle mediated transport GO:0016192 371 0.035
negative regulation of blood vessel morphogenesis GO:2000181 41 0.035
regulation of endothelial cell migration GO:0010594 67 0.034
peripheral nervous system development GO:0007422 2 0.034
gastrulation GO:0007369 51 0.033
peptidyl lysine acetylation GO:0018394 101 0.033
regulation of protein stability GO:0031647 87 0.032
negative regulation of multicellular organismal process GO:0051241 317 0.032
macromolecule glycosylation GO:0043413 63 0.032
endothelial cell morphogenesis GO:0001886 2 0.031
regulation of vasculature development GO:1901342 97 0.031
tube morphogenesis GO:0035239 95 0.030
locomotory behavior GO:0007626 1 0.030
Fly
enzyme linked receptor protein signaling pathway GO:0007167 303 0.030
nitric oxide metabolic process GO:0046209 22 0.030
single organismal cell cell adhesion GO:0016337 148 0.029
negative regulation of cell adhesion GO:0007162 64 0.029
regulation of cell adhesion GO:0030155 166 0.029
purine containing compound catabolic process GO:0072523 411 0.029
response to oxygen levels GO:0070482 100 0.029
regulation of cellular response to growth factor stimulus GO:0090287 76 0.028
lung development GO:0030324 20 0.028
post embryonic hemopoiesis GO:0035166 1 0.027
system process GO:0003008 349 0.027
Rat Fly
negative regulation of cellular component organization GO:0051129 235 0.027
regulation of cellular component movement GO:0051270 334 0.027
neural tube formation GO:0001841 3 0.027
negative regulation of apoptotic process GO:0043066 316 0.027
regulation of protein maturation GO:1903317 150 0.027
sprouting angiogenesis GO:0002040 29 0.026
cell morphogenesis GO:0000902 296 0.026
Fly
purine ribonucleoside metabolic process GO:0046128 437 0.026
histone h3 k9 modification GO:0061647 11 0.026
Mouse Rat Fly
regulation of cysteine type endopeptidase activity GO:2000116 127 0.025
protein maturation GO:0051604 233 0.025
cellular lipid metabolic process GO:0044255 303 0.025
protein dna complex assembly GO:0065004 64 0.025
lung morphogenesis GO:0060425 6 0.025
negative regulation of cellular protein metabolic process GO:0032269 353 0.025
histone methylation GO:0016571 60 0.025
regulation of proteolysis GO:0030162 293 0.024
negative regulation of locomotion GO:0040013 118 0.024
epithelial cell development GO:0002064 34 0.024
regulation of cytokine production GO:0001817 232 0.024
negative regulation of cell migration GO:0030336 102 0.024
positive regulation of hemoglobin biosynthetic process GO:0046985 1 0.024
epithelial cell migration GO:0010631 119 0.024
phototransduction GO:0007602 3 0.024
positive regulation of transcription from rna polymerase ii promoter in response to stress GO:0036003 9 0.024
response to abiotic stimulus GO:0009628 336 0.024
negative regulation of developmental process GO:0051093 247 0.023
regulation of protein ubiquitination GO:0031396 95 0.023
regulation of cell migration involved in sprouting angiogenesis GO:0090049 9 0.023
interleukin 8 production GO:0032637 51 0.023
regulation of cell cell adhesion GO:0022407 57 0.023
erythrocyte homeostasis GO:0034101 31 0.023
regulation of cell cycle GO:0051726 393 0.023
anatomical structure formation involved in morphogenesis GO:0048646 284 0.023
response to decreased oxygen levels GO:0036293 96 0.022
protein processing GO:0016485 226 0.022
negative regulation of phosphate metabolic process GO:0045936 267 0.022
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.022
dna replication dependent nucleosome organization GO:0034723 32 0.022
cellular response to hormone stimulus GO:0032870 125 0.022
cell cell adhesion involved in gastrulation GO:0070586 6 0.021
negative regulation of protein maturation GO:1903318 142 0.021
methylation GO:0032259 106 0.021
endocytosis GO:0006897 159 0.021
negative regulation of cytokine production GO:0001818 82 0.021
response to hormone GO:0009725 175 0.021
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.021
heterotypic cell cell adhesion GO:0034113 28 0.021
hematopoietic or lymphoid organ development GO:0048534 186 0.021
meiotic chromosome segregation GO:0045132 4 0.021
epidermis development GO:0008544 59 0.021
generation of neurons GO:0048699 152 0.020
Fly
neuron differentiation GO:0030182 138 0.020
Fly
negative regulation of endopeptidase activity GO:0010951 84 0.020
modification dependent protein catabolic process GO:0019941 209 0.020
small molecule catabolic process GO:0044282 92 0.019
chromatin assembly GO:0031497 61 0.019
regulation of interleukin 8 production GO:0032677 49 0.019
multicellular organismal aging GO:0010259 3 0.019
primary neural tube formation GO:0014020 3 0.019
positive regulation of fibroblast growth factor receptor signaling pathway GO:0045743 3 0.019
anion transport GO:0006820 161 0.019
mapk cascade GO:0000165 288 0.019
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.019
metencephalon development GO:0022037 2 0.019
cellular protein catabolic process GO:0044257 261 0.019
i kappab kinase nf kappab signaling GO:0007249 166 0.019
organ morphogenesis GO:0009887 147 0.019
negative regulation of peptidase activity GO:0010466 91 0.018
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.018
blood circulation GO:0008015 113 0.018
establishment of planar polarity GO:0001736 3 0.018
nucleotide sugar metabolic process GO:0009225 8 0.018
regulation of cellular response to stress GO:0080135 244 0.018
cell growth GO:0016049 160 0.018
morphogenesis of an epithelium GO:0002009 60 0.018
regulation of epithelial cell migration GO:0010632 93 0.018
female gamete generation GO:0007292 2 0.018
regulation of cell cycle process GO:0010564 266 0.017
regulation of response to cytokine stimulus GO:0060759 46 0.017
protein homooligomerization GO:0051260 100 0.017
regulation of peptidyl lysine acetylation GO:2000756 22 0.017
maintenance of location GO:0051235 112 0.017
negative regulation of chemokine production GO:0032682 9 0.017
response to cytokine GO:0034097 232 0.017
endothelial cell migration GO:0043542 86 0.017
histone h3 k9 methylation GO:0051567 10 0.017
Mouse Rat Fly
epithelium migration GO:0090132 119 0.017
cellular component morphogenesis GO:0032989 314 0.017
Fly
negative regulation of vasculature development GO:1901343 43 0.017
mitotic sister chromatid segregation GO:0000070 53 0.017
ribonucleoside catabolic process GO:0042454 406 0.017
tissue migration GO:0090130 119 0.017
oogenesis GO:0048477 2 0.017
negative regulation of cell cell adhesion GO:0022408 27 0.016
organelle fission GO:0048285 149 0.016
Mouse
hindbrain development GO:0030902 3 0.016
regulation of blood vessel size GO:0050880 18 0.016
nitric oxide biosynthetic process GO:0006809 20 0.016
sister chromatid segregation GO:0000819 54 0.016
myeloid cell homeostasis GO:0002262 34 0.016
negative regulation of phosphorus metabolic process GO:0010563 267 0.016
positive regulation of nucleotide metabolic process GO:0045981 230 0.016
tube closure GO:0060606 3 0.016
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.016
axis elongation GO:0003401 4 0.016
negative regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043154 46 0.016
cell type specific apoptotic process GO:0097285 125 0.016
spermatid differentiation GO:0048515 4 0.016
Mouse
response to fluid shear stress GO:0034405 14 0.016
neuron death GO:0070997 65 0.016
collagen metabolic process GO:0032963 28 0.016
regulation of anatomical structure size GO:0090066 101 0.016
positive regulation of exosomal secretion GO:1903543 12 0.015
negative regulation of cell differentiation GO:0045596 171 0.015
negative regulation of cysteine type endopeptidase activity GO:2000117 48 0.015
negative regulation of programmed cell death GO:0043069 321 0.015
secretion by cell GO:0032940 226 0.015
ubiquitin dependent protein catabolic process GO:0006511 206 0.015
cell part morphogenesis GO:0032990 137 0.015
Fly
determination of adult lifespan GO:0008340 2 0.015
regulation of dna replication GO:0006275 68 0.015
positive regulation of growth GO:0045927 58 0.015
cellular response to hypoxia GO:0071456 51 0.015
negative regulation of hydrolase activity GO:0051346 182 0.015
cell fate determination GO:0001709 3 0.015
meiosis i GO:0007127 4 0.015
Mouse
ras protein signal transduction GO:0007265 73 0.015
negative regulation of protein modification process GO:0031400 200 0.015
negative regulation of cell death GO:0060548 345 0.015
negative regulation of proteolysis GO:0045861 132 0.015
regulation of small gtpase mediated signal transduction GO:0051056 156 0.015
negative regulation of jak stat cascade GO:0046426 4 0.014
peptidyl lysine dimethylation GO:0018027 3 0.014
cellular response to oxygen containing compound GO:1901701 276 0.014
Fly
negative regulation of cell cycle GO:0045786 193 0.014
positive regulation of nitric oxide biosynthetic process GO:0045429 13 0.014
regulation of cytokine biosynthetic process GO:0042035 35 0.014
negative regulation of peptidyl lysine acetylation GO:2000757 8 0.014
memory GO:0007613 3 0.014
Rat Fly
lipid metabolic process GO:0006629 381 0.014
regulation of locomotion GO:0040012 329 0.014
regulation of cell migration GO:0030334 289 0.014
regulation of angiogenesis GO:0045765 92 0.014
dna conformation change GO:0071103 113 0.014
dna hypermethylation GO:0044026 1 0.014
growth GO:0040007 202 0.014
Mouse
cellular response to cytokine stimulus GO:0071345 181 0.014
erythrocyte differentiation GO:0030218 28 0.014
protein deacylation GO:0035601 39 0.014
neurogenesis GO:0022008 169 0.014
Fly
regulation of neural precursor cell proliferation GO:2000177 4 0.014
negative regulation of growth GO:0045926 97 0.014
cell projection morphogenesis GO:0048858 129 0.014
Fly
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.013
glycoprotein metabolic process GO:0009100 110 0.013
negative regulation of heterotypic cell cell adhesion GO:0034115 6 0.013
protein dna complex subunit organization GO:0071824 80 0.013
proteasomal protein catabolic process GO:0010498 176 0.013
embryonic epithelial tube formation GO:0001838 4 0.013
negative regulation of intracellular signal transduction GO:1902532 183 0.013
nervous system development GO:0007399 293 0.013
Fly
organophosphate catabolic process GO:0046434 430 0.013
negative regulation of cell growth GO:0030308 83 0.013
glycosyl compound catabolic process GO:1901658 413 0.013
negative regulation of angiogenesis GO:0016525 39 0.013
receptor mediated endocytosis GO:0006898 84 0.013
regulation of mitosis GO:0007088 63 0.013
positive regulation of cell development GO:0010720 92 0.013
Fly
nucleoside monophosphate metabolic process GO:0009123 191 0.013
chromosome segregation GO:0007059 114 0.013
taxis GO:0042330 157 0.013
establishment or maintenance of bipolar cell polarity GO:0061245 2 0.013
single organism membrane organization GO:0044802 268 0.012
posttranscriptional regulation of gene expression GO:0010608 213 0.012
adult locomotory behavior GO:0008344 1 0.012
small molecule biosynthetic process GO:0044283 157 0.012
sex determination GO:0007530 3 0.012
purine nucleoside catabolic process GO:0006152 398 0.012
neuromuscular junction development GO:0007528 3 0.012
response to lipid GO:0033993 206 0.012
Fly
regulation of blood vessel endothelial cell migration GO:0043535 30 0.012
segmentation GO:0035282 4 0.012
organophosphate biosynthetic process GO:0090407 163 0.012
nucleoside triphosphate metabolic process GO:0009141 422 0.012
blood vessel morphogenesis GO:0048514 162 0.012
endothelial cell differentiation GO:0045446 26 0.012
embryonic digestive tract morphogenesis GO:0048557 2 0.012
organic acid biosynthetic process GO:0016053 97 0.012
mitotic cell cycle process GO:1903047 286 0.012
regulation of cell cell adhesion involved in gastrulation GO:0070587 6 0.012
nerve development GO:0021675 4 0.012
regulation of nucleotide metabolic process GO:0006140 269 0.012
regulation of interleukin 8 biosynthetic process GO:0045414 11 0.012
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.012
fatty acid metabolic process GO:0006631 115 0.012
embryo development ending in birth or egg hatching GO:0009792 34 0.011
response to radiation GO:0009314 151 0.011
phototransduction visible light GO:0007603 2 0.011
regulation of cell morphogenesis GO:0022604 153 0.011
Fly
regulation of transforming growth factor beta receptor signaling pathway GO:0017015 48 0.011
angiogenesis GO:0001525 147 0.011
cytokine metabolic process GO:0042107 38 0.011
regulation of protein acetylation GO:1901983 25 0.011
skin development GO:0043588 76 0.011
digestive tract development GO:0048565 75 0.011
reproduction GO:0000003 63 0.011
Mouse
protein localization to membrane GO:0072657 160 0.011
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 91 0.011
positive regulation of cell cycle process GO:0090068 106 0.011
wnt signaling pathway GO:0016055 156 0.011
vascular process in circulatory system GO:0003018 29 0.011
positive regulation of dna metabolic process GO:0051054 73 0.011
associative learning GO:0008306 1 0.011
regulation of nitric oxide biosynthetic process GO:0045428 17 0.011
somitogenesis GO:0001756 2 0.011
signal transduction by phosphorylation GO:0023014 297 0.011
macromolecule deacylation GO:0098732 41 0.011
endosome transport via multivesicular body sorting pathway GO:0032509 3 0.011
hemopoiesis GO:0030097 180 0.011
regulation of neurogenesis GO:0050767 82 0.011
Fly
cytokine biosynthetic process GO:0042089 37 0.011
cellular modified amino acid metabolic process GO:0006575 64 0.011
exosomal secretion GO:1990182 15 0.011
purine nucleoside triphosphate catabolic process GO:0009146 392 0.011
blood vessel endothelial cell migration GO:0043534 42 0.010
morphogenesis of a polarized epithelium GO:0001738 3 0.010
regulation of canonical wnt signaling pathway GO:0060828 88 0.010
gene silencing GO:0016458 49 0.010
positive regulation of cellular component organization GO:0051130 376 0.010
Fly
response to ionizing radiation GO:0010212 65 0.010
negative regulation of cell migration involved in sprouting angiogenesis GO:0090051 6 0.010
spermatid development GO:0007286 4 0.010
Mouse
negative regulation of organelle organization GO:0010639 126 0.010
modulation of growth of symbiont involved in interaction with host GO:0044144 2 0.010
purine nucleoside triphosphate metabolic process GO:0009144 412 0.010
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.010
regulation of secretion GO:0051046 194 0.010
protein catabolic process GO:0030163 325 0.010
positive regulation of organelle organization GO:0010638 195 0.010
response to hypoxia GO:0001666 96 0.010
membrane protein proteolysis GO:0033619 38 0.010
regulation of cell motility GO:2000145 299 0.010
negative regulation of neural precursor cell proliferation GO:2000178 1 0.010
organic anion transport GO:0015711 103 0.010

EHMT2 disease predictions

Disease DO term ID Size Probability Func Analog Org
urinary system disease DOID:18 40 0.027
cancer DOID:162 167 0.021
disease of cellular proliferation DOID:14566 174 0.021
organ system cancer DOID:0050686 164 0.021
kidney disease DOID:557 36 0.020
disease of metabolism DOID:0014667 295 0.013