|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.543
|
Mouse Fly |
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.444
|
Mouse Fly |
|
|
regulation of organ formation
|
GO:0003156 |
4 |
0.431
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.404
|
Worm Fly |
|
|
regulation of cardioblast differentiation
|
GO:0051890 |
4 |
0.366
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.364
|
|
|
|
regulation of proteasomal protein catabolic process
|
GO:0061136 |
87 |
0.330
|
Mouse Fly |
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
212 |
0.322
|
Mouse Fly |
|
|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
156 |
0.322
|
Mouse Fly |
|
|
positive regulation of proteolysis
|
GO:0045862 |
142 |
0.322
|
Mouse Fly |
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.316
|
|
|
|
negative regulation of transcription from rna polymerase ii promoter
|
GO:0000122 |
281 |
0.277
|
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
206 |
0.273
|
Mouse Fly |
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.243
|
|
|
|
neural tube formation
|
GO:0001841 |
3 |
0.229
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.225
|
Mouse Fly |
|
|
cell division
|
GO:0051301 |
168 |
0.219
|
Fly |
|
|
segmentation
|
GO:0035282 |
4 |
0.203
|
|
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
84 |
0.202
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.194
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.191
|
|
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.190
|
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.188
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.186
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
207 |
0.186
|
|
|
|
notch signaling pathway
|
GO:0007219 |
31 |
0.182
|
|
|
|
bmp signaling pathway
|
GO:0030509 |
49 |
0.181
|
|
|
|
primary neural tube formation
|
GO:0014020 |
3 |
0.178
|
|
|
|
oogenesis
|
GO:0048477 |
2 |
0.178
|
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
209 |
0.176
|
Mouse Fly |
|
|
lipid biosynthetic process
|
GO:0008610 |
177 |
0.175
|
|
|
|
actin filament based process
|
GO:0030029 |
224 |
0.175
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.174
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.173
|
Fly |
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
4 |
0.165
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
189 |
0.162
|
|
|
|
response to other organism
|
GO:0051707 |
261 |
0.158
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.154
|
|
|
|
establishment or maintenance of epithelial cell apical basal polarity
|
GO:0045197 |
1 |
0.153
|
|
|
|
cell fate determination
|
GO:0001709 |
3 |
0.152
|
|
|
|
establishment or maintenance of apical basal cell polarity
|
GO:0035088 |
2 |
0.149
|
|
|
|
positive regulation of jnk cascade
|
GO:0046330 |
52 |
0.147
|
|
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.145
|
Mouse Fly |
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.144
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.139
|
Yeast |
|
|
regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903050 |
91 |
0.137
|
Mouse Fly |
|
|
positive regulation of proteasomal protein catabolic process
|
GO:1901800 |
35 |
0.136
|
Mouse Fly |
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
125 |
0.135
|
|
|
|
motor neuron axon guidance
|
GO:0008045 |
2 |
0.133
|
|
|
|
positive regulation of cellular protein catabolic process
|
GO:1903364 |
37 |
0.133
|
Mouse Fly |
|
|
cellular protein catabolic process
|
GO:0044257 |
261 |
0.131
|
Mouse Fly |
|
|
regulation of response to external stimulus
|
GO:0032101 |
222 |
0.131
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.129
|
Yeast |
|
|
positive regulation of proteasomal ubiquitin dependent protein catabolic process
|
GO:0032436 |
30 |
0.128
|
Mouse Fly |
|
|
growth
|
GO:0040007 |
202 |
0.127
|
Worm Fly |
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.127
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.126
|
|
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.125
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.123
|
Yeast |
|
|
cofactor metabolic process
|
GO:0051186 |
87 |
0.123
|
|
|
|
microtubule based process
|
GO:0007017 |
210 |
0.121
|
|
|
|
regulation of transforming growth factor beta receptor signaling pathway
|
GO:0017015 |
48 |
0.120
|
|
|
|
stem cell division
|
GO:0017145 |
2 |
0.120
|
|
|
|
transforming growth factor beta receptor signaling pathway
|
GO:0007179 |
76 |
0.118
|
|
|
|
axis elongation
|
GO:0003401 |
4 |
0.118
|
|
|
|
establishment or maintenance of monopolar cell polarity
|
GO:0061339 |
1 |
0.116
|
|
|
|
neural tube closure
|
GO:0001843 |
3 |
0.116
|
|
|
|
regulation of heart induction
|
GO:0090381 |
2 |
0.115
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
211 |
0.115
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.113
|
|
|
|
taxis
|
GO:0042330 |
157 |
0.112
|
|
|
|
regulation of stress activated protein kinase signaling cascade
|
GO:0070302 |
85 |
0.111
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
342 |
0.111
|
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.108
|
|
|
|
dna repair
|
GO:0006281 |
198 |
0.108
|
Yeast |
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.108
|
|
|
|
embryonic morphogenesis
|
GO:0048598 |
85 |
0.108
|
|
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
144 |
0.108
|
|
|
|
establishment of planar polarity
|
GO:0001736 |
3 |
0.105
|
Fly |
|
|
lipid metabolic process
|
GO:0006629 |
381 |
0.104
|
|
|
|
positive regulation of i kappab kinase nf kappab signaling
|
GO:0043123 |
132 |
0.104
|
|
|
|
regulation of cellular response to growth factor stimulus
|
GO:0090287 |
76 |
0.103
|
|
|
|
cell adhesion
|
GO:0007155 |
325 |
0.103
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.103
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
175 |
0.101
|
|
|
|
establishment or maintenance of bipolar cell polarity
|
GO:0061245 |
2 |
0.101
|
|
|
|
non canonical wnt signaling pathway
|
GO:0035567 |
14 |
0.101
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.100
|
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
155 |
0.099
|
Mouse Fly |
|
|
embryo development
|
GO:0009790 |
123 |
0.098
|
Worm |
|
|
embryonic epithelial tube formation
|
GO:0001838 |
4 |
0.096
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.096
|
|
|
|
steroid metabolic process
|
GO:0008202 |
94 |
0.093
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.091
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
209 |
0.090
|
|
|
|
proteasomal protein catabolic process
|
GO:0010498 |
176 |
0.090
|
Mouse Fly |
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
205 |
0.090
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.089
|
|
|
|
negative regulation of cell cycle phase transition
|
GO:1901988 |
89 |
0.089
|
|
|
|
regulation of jnk cascade
|
GO:0046328 |
73 |
0.088
|
|
|
|
somitogenesis
|
GO:0001756 |
2 |
0.087
|
|
|
|
negative regulation of cardioblast cell fate specification
|
GO:0009997 |
1 |
0.087
|
|
|
|
positive regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903052 |
35 |
0.087
|
Mouse Fly |
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.086
|
|
|
|
protein autophosphorylation
|
GO:0046777 |
123 |
0.085
|
Fly |
|
|
circulatory system development
|
GO:0072359 |
262 |
0.085
|
|
|
|
regulation of endopeptidase activity
|
GO:0052548 |
170 |
0.085
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.084
|
|
|
|
regulation of proteasomal ubiquitin dependent protein catabolic process
|
GO:0032434 |
71 |
0.082
|
Mouse Fly |
|
|
protein oligomerization
|
GO:0051259 |
173 |
0.082
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.081
|
|
|
|
regulation of cellular protein catabolic process
|
GO:1903362 |
96 |
0.080
|
Mouse Fly |
|
|
mitochondrion organization
|
GO:0007005 |
156 |
0.079
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.079
|
|
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
186 |
0.079
|
|
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.078
|
|
|
|
embryonic eye morphogenesis
|
GO:0048048 |
2 |
0.078
|
|
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.077
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.076
|
|
|
|
neural crest cell development
|
GO:0014032 |
3 |
0.076
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.076
|
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
94 |
0.074
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
239 |
0.074
|
|
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
147 |
0.074
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
230 |
0.073
|
|
|
|
regulation of heart morphogenesis
|
GO:2000826 |
4 |
0.072
|
|
|
|
negative regulation of cell growth
|
GO:0030308 |
83 |
0.071
|
|
|
|
negative regulation of cell fate commitment
|
GO:0010454 |
3 |
0.071
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
244 |
0.071
|
|
|
|
regulation of hormone levels
|
GO:0010817 |
125 |
0.070
|
Fly |
|
|
dephosphorylation
|
GO:0016311 |
209 |
0.070
|
|
|
|
tube development
|
GO:0035295 |
125 |
0.070
|
|
|
|
maintenance of location
|
GO:0051235 |
112 |
0.069
|
Yeast |
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.069
|
|
|
|
tube closure
|
GO:0060606 |
3 |
0.068
|
|
|
|
cell growth
|
GO:0016049 |
160 |
0.068
|
Fly |
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.068
|
|
|
|
response to external biotic stimulus
|
GO:0043207 |
261 |
0.068
|
|
|
|
actin filament organization
|
GO:0007015 |
128 |
0.067
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.066
|
Worm |
|
|
somatic stem cell maintenance
|
GO:0035019 |
4 |
0.066
|
|
|
|
receptor metabolic process
|
GO:0043112 |
81 |
0.066
|
|
|
|
positive regulation of gtpase activity
|
GO:0043547 |
166 |
0.066
|
|
|
|
neuron projection development
|
GO:0031175 |
106 |
0.065
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.065
|
|
|
|
small molecule biosynthetic process
|
GO:0044283 |
157 |
0.064
|
|
|
|
regulation of cell growth
|
GO:0001558 |
135 |
0.064
|
Fly |
|
|
heart field specification
|
GO:0003128 |
2 |
0.064
|
|
|
|
non canonical wnt signaling pathway via mapk cascade
|
GO:0038030 |
4 |
0.064
|
|
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
324 |
0.063
|
|
|
|
rna processing
|
GO:0006396 |
255 |
0.063
|
Yeast |
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
166 |
0.063
|
|
|
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
116 |
0.063
|
|
|
|
protein ubiquitination
|
GO:0016567 |
314 |
0.063
|
|
|
|
canonical wnt signaling pathway involved in heart development
|
GO:0061316 |
3 |
0.063
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.062
|
|
|
|
anterior posterior axis specification
|
GO:0009948 |
2 |
0.062
|
|
|
|
asymmetric stem cell division
|
GO:0098722 |
1 |
0.062
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
119 |
0.062
|
|
|
|
positive regulation of aldosterone biosynthetic process
|
GO:0032349 |
2 |
0.061
|
|
|
|
lens development in camera type eye
|
GO:0002088 |
2 |
0.061
|
|
|
|
heart development
|
GO:0007507 |
95 |
0.061
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.061
|
|
|
|
epidermis morphogenesis
|
GO:0048730 |
3 |
0.060
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
136 |
0.060
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.060
|
Fly |
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
392 |
0.060
|
|
|
|
secretion by cell
|
GO:0032940 |
226 |
0.060
|
Fly |
|
|
heart induction
|
GO:0003129 |
4 |
0.058
|
|
|
|
establishment of tissue polarity
|
GO:0007164 |
3 |
0.057
|
Fly |
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.057
|
|
|
|
embryonic organ development
|
GO:0048568 |
36 |
0.057
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.056
|
Fly |
|
|
organ formation
|
GO:0048645 |
3 |
0.056
|
|
|
|
response to growth factor
|
GO:0070848 |
205 |
0.056
|
|
|
|
mitotic nuclear division
|
GO:0007067 |
119 |
0.056
|
Yeast |
|
|
negative regulation of transcription initiation from rna polymerase ii promoter
|
GO:0060633 |
3 |
0.055
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
0.055
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.055
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.055
|
|
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.055
|
Fly |
|
|
rho protein signal transduction
|
GO:0007266 |
26 |
0.054
|
|
|
|
steroid biosynthetic process
|
GO:0006694 |
46 |
0.054
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.054
|
|
|
|
alcohol metabolic process
|
GO:0006066 |
114 |
0.054
|
|
|
|
biological adhesion
|
GO:0022610 |
331 |
0.053
|
|
|
|
retinal ganglion cell axon guidance
|
GO:0031290 |
2 |
0.053
|
|
|
|
rhythmic behavior
|
GO:0007622 |
2 |
0.053
|
Fly |
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.052
|
|
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.052
|
|
|
|
potassium ion transmembrane transport
|
GO:0071805 |
60 |
0.052
|
|
|
|
regulation of stem cell differentiation
|
GO:2000736 |
56 |
0.052
|
|
|
|
regulation of i kappab kinase nf kappab signaling
|
GO:0043122 |
162 |
0.052
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.052
|
|
|
|
somatic stem cell division
|
GO:0048103 |
1 |
0.052
|
|
|
|
positive regulation of wnt signaling pathway
|
GO:0030177 |
54 |
0.052
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
92 |
0.051
|
|
|
|
regulation of cell development
|
GO:0060284 |
161 |
0.051
|
|
|
|
reproductive system development
|
GO:0061458 |
56 |
0.051
|
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
97 |
0.050
|
|
|
|
negative regulation of catabolic process
|
GO:0009895 |
104 |
0.050
|
|
|
|
defense response
|
GO:0006952 |
315 |
0.050
|
|
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
166 |
0.050
|
|
|
|
vesicle organization
|
GO:0016050 |
62 |
0.050
|
|
|
|
morphogenesis of a polarized epithelium
|
GO:0001738 |
3 |
0.049
|
Fly |
|
|
stem cell differentiation
|
GO:0048863 |
93 |
0.049
|
|
|
|
nuclear transport
|
GO:0051169 |
179 |
0.048
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
244 |
0.048
|
Mouse Fly |
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.048
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.048
|
|
|
|
regulation of response to dna damage stimulus
|
GO:2001020 |
94 |
0.047
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.047
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
269 |
0.047
|
|
|
|
positive regulation of jun kinase activity
|
GO:0043507 |
23 |
0.047
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.046
|
|
|
|
jnk cascade
|
GO:0007254 |
80 |
0.046
|
|
|
|
regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090092 |
90 |
0.046
|
|
|
|
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090101 |
45 |
0.046
|
|
|
|
positive regulation of cell adhesion
|
GO:0045785 |
84 |
0.046
|
|
|
|
heart morphogenesis
|
GO:0003007 |
48 |
0.046
|
|
|
|
embryonic placenta development
|
GO:0001892 |
1 |
0.046
|
|
|
|
locomotory behavior
|
GO:0007626 |
1 |
0.046
|
Fly |
|
|
stem cell development
|
GO:0048864 |
69 |
0.045
|
|
|
|
mapk cascade
|
GO:0000165 |
288 |
0.045
|
|
|
|
hormone transport
|
GO:0009914 |
68 |
0.045
|
Fly |
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.045
|
|
|
|
response to fungus
|
GO:0009620 |
4 |
0.044
|
|
|
|
establishment of monopolar cell polarity
|
GO:0061162 |
1 |
0.044
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
408 |
0.044
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.043
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
380 |
0.043
|
Mouse Fly |
|
|
oocyte differentiation
|
GO:0009994 |
2 |
0.043
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.043
|
|
|
|
ncrna processing
|
GO:0034470 |
83 |
0.042
|
Yeast |
|
|
regulation of intrinsic apoptotic signaling pathway
|
GO:2001242 |
72 |
0.042
|
|
|
|
regulation of actin filament based process
|
GO:0032970 |
141 |
0.042
|
|
|
|
gtp catabolic process
|
GO:0006184 |
237 |
0.042
|
|
|
|
cell cycle phase transition
|
GO:0044770 |
173 |
0.042
|
|
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.042
|
|
|
|
reproductive process
|
GO:0022414 |
106 |
0.042
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
140 |
0.041
|
|
|
|
neuroblast proliferation
|
GO:0007405 |
4 |
0.041
|
|
|
|
autophagy
|
GO:0006914 |
88 |
0.041
|
|
|
|
establishment of apical basal cell polarity
|
GO:0035089 |
1 |
0.041
|
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
180 |
0.040
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.040
|
|
|
|
positive regulation of stress activated mapk cascade
|
GO:0032874 |
60 |
0.040
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
394 |
0.040
|
|
|
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
185 |
0.040
|
|
|
|
behavior
|
GO:0007610 |
112 |
0.039
|
Fly |
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.039
|
|
|
|
fatty acid metabolic process
|
GO:0006631 |
115 |
0.039
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
179 |
0.039
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.038
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.038
|
|
|
|
coenzyme metabolic process
|
GO:0006732 |
65 |
0.038
|
|
|
|
positive regulation of protein catabolic process
|
GO:0045732 |
75 |
0.038
|
Mouse Fly |
|
|
cardiovascular system development
|
GO:0072358 |
262 |
0.038
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.038
|
|
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
70 |
0.037
|
|
|
|
negative regulation of cell cycle process
|
GO:0010948 |
121 |
0.037
|
|
|
|
regulation of growth
|
GO:0040008 |
165 |
0.036
|
Worm Fly |
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
227 |
0.036
|
|
|
|
epithelial tube morphogenesis
|
GO:0060562 |
38 |
0.036
|
|
|
|
cochlea development
|
GO:0090102 |
1 |
0.036
|
|
|
|
regulation of autophagy
|
GO:0010506 |
52 |
0.036
|
|
|
|
positive regulation of ras gtpase activity
|
GO:0032320 |
117 |
0.036
|
|
|
|
histone modification
|
GO:0016570 |
251 |
0.036
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.035
|
|
|
|
negative regulation of cell differentiation
|
GO:0045596 |
171 |
0.035
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.035
|
Fly |
|
|
regulation of immune response
|
GO:0050776 |
201 |
0.034
|
|
|
|
cation transport
|
GO:0006812 |
331 |
0.034
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
398 |
0.034
|
|
|
|
regulation of behavior
|
GO:0050795 |
82 |
0.034
|
|
|
|
tube morphogenesis
|
GO:0035239 |
95 |
0.033
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.033
|
|
|
|
regulation of binding
|
GO:0051098 |
111 |
0.033
|
|
|
|
regulation of cysteine type endopeptidase activity
|
GO:2000116 |
127 |
0.033
|
|
|
|
negative regulation of protein kinase activity
|
GO:0006469 |
98 |
0.033
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.033
|
Yeast |
|
|
inner ear morphogenesis
|
GO:0042472 |
4 |
0.033
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
177 |
0.033
|
|
|
|
cell projection organization
|
GO:0030030 |
252 |
0.032
|
Fly |
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
264 |
0.032
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
412 |
0.032
|
|
|
|
female gonad development
|
GO:0008585 |
10 |
0.032
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.032
|
|
|
|
neuron fate commitment
|
GO:0048663 |
2 |
0.032
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
204 |
0.032
|
Fly |
|
|
purine containing compound catabolic process
|
GO:0072523 |
411 |
0.032
|
|
|
|
chemical homeostasis
|
GO:0048878 |
306 |
0.032
|
|
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.031
|
|
|
|
gastrulation
|
GO:0007369 |
51 |
0.031
|
|
|
|
lens morphogenesis in camera type eye
|
GO:0002089 |
2 |
0.031
|
|
|
|
defense response to other organism
|
GO:0098542 |
129 |
0.031
|
|
|
|
regulation of metal ion transport
|
GO:0010959 |
120 |
0.031
|
|
|
|
embryo development ending in birth or egg hatching
|
GO:0009792 |
34 |
0.031
|
Worm |
|
|
regulation of organ morphogenesis
|
GO:2000027 |
24 |
0.030
|
|
|
|
regulation of multi organism process
|
GO:0043900 |
157 |
0.030
|
|
|
|
regulation of dna metabolic process
|
GO:0051052 |
153 |
0.030
|
|
|
|
negative regulation of heart induction by canonical wnt signaling pathway
|
GO:0003136 |
1 |
0.030
|
|
|
|
membrane organization
|
GO:0061024 |
292 |
0.030
|
|
|
|
neuron development
|
GO:0048666 |
113 |
0.030
|
|
|
|
developmental process involved in reproduction
|
GO:0003006 |
66 |
0.030
|
|
|
|
regulation of lipid biosynthetic process
|
GO:0046890 |
47 |
0.030
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.030
|
|
|
|
convergent extension
|
GO:0060026 |
1 |
0.030
|
|
|
|
glycerolipid metabolic process
|
GO:0046486 |
107 |
0.030
|
|
|
|
lipid localization
|
GO:0010876 |
106 |
0.029
|
Fly |
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.029
|
|
|
|
regulation of defense response
|
GO:0031347 |
154 |
0.029
|
|
|
|
positive regulation of response to external stimulus
|
GO:0032103 |
88 |
0.029
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
135 |
0.028
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.028
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
405 |
0.028
|
|
|
|
heart formation
|
GO:0060914 |
2 |
0.028
|
|
|
|
regulation of cell morphogenesis
|
GO:0022604 |
153 |
0.028
|
|
|
|
regulation of protein ubiquitination
|
GO:0031396 |
95 |
0.028
|
|
|
|
focal adhesion assembly
|
GO:0048041 |
30 |
0.028
|
|
|
|
regulation of rho gtpase activity
|
GO:0032319 |
66 |
0.028
|
|
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
131 |
0.028
|
|
|
|
protein localization to membrane
|
GO:0072657 |
160 |
0.028
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.028
|
|
|
|
cell cell junction organization
|
GO:0045216 |
69 |
0.028
|
|
|
|
mitotic cell cycle phase transition
|
GO:0044772 |
162 |
0.028
|
|
|
|
internal protein amino acid acetylation
|
GO:0006475 |
101 |
0.027
|
|
|
|
chemotaxis
|
GO:0006935 |
157 |
0.027
|
|
|
|
regeneration
|
GO:0031099 |
4 |
0.027
|
|
|
|
lymphocyte proliferation
|
GO:0046651 |
70 |
0.027
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
180 |
0.027
|
|
|
|
stress activated mapk cascade
|
GO:0051403 |
93 |
0.027
|
|
|
|
regulation of neural precursor cell proliferation
|
GO:2000177 |
4 |
0.027
|
|
|
|
epithelium development
|
GO:0060429 |
227 |
0.027
|
Fly |
|
|
regulation of glial cell proliferation
|
GO:0060251 |
4 |
0.027
|
|
|
|
single organism reproductive process
|
GO:0044702 |
98 |
0.027
|
|
|
|
response to bacterium
|
GO:0009617 |
144 |
0.026
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.026
|
Yeast |
|
|
vacuolar transport
|
GO:0007034 |
34 |
0.026
|
|
|
|
monovalent inorganic cation transport
|
GO:0015672 |
128 |
0.026
|
|
|
|
regulation of bmp signaling pathway
|
GO:0030510 |
27 |
0.026
|
|
|
|
negative regulation of t cell cytokine production
|
GO:0002725 |
4 |
0.026
|
|
|
|
chromosome segregation
|
GO:0007059 |
114 |
0.026
|
Yeast |
|
|
canonical wnt signaling pathway involved in regulation of cell proliferation
|
GO:0044340 |
2 |
0.026
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
303 |
0.026
|
|
|
|
histone acetylation
|
GO:0016573 |
93 |
0.026
|
|
|
|
intracellular receptor signaling pathway
|
GO:0030522 |
104 |
0.025
|
|
|
|
postsynaptic membrane organization
|
GO:0001941 |
2 |
0.025
|
|
|
|
skin development
|
GO:0043588 |
76 |
0.025
|
Fly |
|
|
endomembrane system organization
|
GO:0010256 |
196 |
0.025
|
|
|
|
endosomal transport
|
GO:0016197 |
129 |
0.025
|
|
|
|
positive regulation of lipid biosynthetic process
|
GO:0046889 |
22 |
0.025
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.025
|
|
|
|
cellular cation homeostasis
|
GO:0030003 |
163 |
0.025
|
|
|
|
response to radiation
|
GO:0009314 |
151 |
0.025
|
|
|
|
response to hypoxia
|
GO:0001666 |
96 |
0.025
|
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
127 |
0.025
|
|
|
|
reproduction
|
GO:0000003 |
63 |
0.025
|
Yeast Worm |
|
|
actin filament bundle organization
|
GO:0061572 |
54 |
0.024
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
205 |
0.024
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
193 |
0.024
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.024
|
|
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
185 |
0.024
|
|
|
|
positive regulation of cell morphogenesis involved in differentiation
|
GO:0010770 |
50 |
0.024
|
|
|
|
alcohol biosynthetic process
|
GO:0046165 |
52 |
0.024
|
|
|
|
digestive system development
|
GO:0055123 |
75 |
0.024
|
|
|
|
cofactor biosynthetic process
|
GO:0051188 |
31 |
0.024
|
|
|
|
meiosis i
|
GO:0007127 |
4 |
0.024
|
Yeast |
|
|
multicellular organism reproduction
|
GO:0032504 |
42 |
0.024
|
|
|
|
regulation of cell morphogenesis involved in differentiation
|
GO:0010769 |
83 |
0.024
|
|
|
|
regulation of nervous system development
|
GO:0051960 |
88 |
0.024
|
|
|
|
cell part morphogenesis
|
GO:0032990 |
137 |
0.024
|
|
|
|
positive regulation of map kinase activity
|
GO:0043406 |
80 |
0.023
|
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
130 |
0.023
|
|
|
|
organ induction
|
GO:0001759 |
4 |
0.023
|
|
|
|
organelle fission
|
GO:0048285 |
149 |
0.023
|
Yeast |
|
|
response to transforming growth factor beta
|
GO:0071559 |
94 |
0.023
|
|
|
|
defense response to fungus
|
GO:0050832 |
4 |
0.023
|
|
|
|
regulation of ras gtpase activity
|
GO:0032318 |
128 |
0.023
|
|
|
|
epithelium migration
|
GO:0090132 |
119 |
0.023
|
|
|
|
regulation of ion transport
|
GO:0043269 |
189 |
0.023
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.023
|
|
|
|
regulation of potassium ion transmembrane transporter activity
|
GO:1901016 |
16 |
0.023
|
|
|
|
negative regulation of mitotic cell cycle phase transition
|
GO:1901991 |
85 |
0.023
|
|
|
|
regulation of actin filament bundle assembly
|
GO:0032231 |
36 |
0.022
|
|
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.022
|
Fly |
|
|
regulation of ion homeostasis
|
GO:2000021 |
73 |
0.022
|
|
|
|
brain development
|
GO:0007420 |
97 |
0.022
|
|
|
|
cardiac cell fate specification
|
GO:0060912 |
1 |
0.022
|
|
|
|
protein targeting
|
GO:0006605 |
187 |
0.022
|
|
|
|
negative regulation of organelle organization
|
GO:0010639 |
126 |
0.022
|
|
|
|
morphogenesis of an epithelium
|
GO:0002009 |
60 |
0.022
|
Fly |
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
113 |
0.022
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
172 |
0.022
|
|
|
|
reproductive structure development
|
GO:0048608 |
55 |
0.022
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
107 |
0.022
|
|
|
|
startle response
|
GO:0001964 |
3 |
0.022
|
|
|
|
rna export from nucleus
|
GO:0006405 |
33 |
0.022
|
|
|
|
negative regulation of protein maturation
|
GO:1903318 |
142 |
0.022
|
|
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.021
|
|
|
|
chromatin modification
|
GO:0016568 |
298 |
0.021
|
|
|
|
syncytium formation by plasma membrane fusion
|
GO:0000768 |
2 |
0.021
|
|
|
|
positive regulation of peptidase activity
|
GO:0010952 |
88 |
0.021
|
|
|
|
negative regulation of gliogenesis
|
GO:0014014 |
3 |
0.021
|
|
|
|
regulation of isoprenoid metabolic process
|
GO:0019747 |
1 |
0.021
|
|
|
|
regulation of alkaline phosphatase activity
|
GO:0010692 |
2 |
0.021
|
|
|
|
cell substrate adherens junction assembly
|
GO:0007045 |
30 |
0.021
|
|
|
|
non canonical wnt signaling pathway via jnk cascade
|
GO:0038031 |
3 |
0.021
|
|
|
|
actin filament bundle assembly
|
GO:0051017 |
54 |
0.021
|
|
|
|
regulation of jun kinase activity
|
GO:0043506 |
27 |
0.021
|
|
|
|
positive regulation of stress activated protein kinase signaling cascade
|
GO:0070304 |
61 |
0.021
|
|
|
|
meiotic chromosome segregation
|
GO:0045132 |
4 |
0.021
|
Yeast |
|
|
cell projection morphogenesis
|
GO:0048858 |
129 |
0.021
|
|
|
|
mesenchymal cell development
|
GO:0014031 |
50 |
0.021
|
|
|
|
protein homooligomerization
|
GO:0051260 |
100 |
0.020
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
155 |
0.020
|
|
|
|
negative regulation of transferase activity
|
GO:0051348 |
124 |
0.020
|
|
|
|
negative regulation of protein catabolic process
|
GO:0042177 |
59 |
0.020
|
|
|
|
ion homeostasis
|
GO:0050801 |
230 |
0.020
|
|
|
|
metal ion transport
|
GO:0030001 |
272 |
0.020
|
|
|
|
pharynx development
|
GO:0060465 |
1 |
0.020
|
|
|
|
cellular response to extracellular stimulus
|
GO:0031668 |
72 |
0.020
|
|
|
|
cardioblast cell fate commitment
|
GO:0042684 |
1 |
0.020
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.020
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
191 |
0.020
|
|
|
|
muscle structure development
|
GO:0061061 |
98 |
0.020
|
|
|
|
outflow tract septum morphogenesis
|
GO:0003148 |
4 |
0.020
|
|
|
|
negative regulation of transcription from rna polymerase ii promoter in response to uv induced dna damage
|
GO:0010768 |
1 |
0.020
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.020
|
|
|
|
negative regulation of kinase activity
|
GO:0033673 |
106 |
0.020
|
|
|
|
inflammatory response
|
GO:0006954 |
79 |
0.019
|
|
|
|
tissue morphogenesis
|
GO:0048729 |
96 |
0.019
|
Fly |
|
|
oocyte development
|
GO:0048599 |
1 |
0.019
|
|
|
|
regulation of notch signaling pathway
|
GO:0008593 |
18 |
0.019
|
|
|
|
negative regulation of growth
|
GO:0045926 |
97 |
0.019
|
|
|
|
positive regulation of hormone biosynthetic process
|
GO:0046886 |
4 |
0.019
|
|
|
|
negative regulation of ion transport
|
GO:0043271 |
39 |
0.019
|
|
|
|
circadian behavior
|
GO:0048512 |
2 |
0.019
|
Fly |
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.019
|
|
|
|
regulation of chromosome organization
|
GO:0033044 |
103 |
0.019
|
|
|
|
cation homeostasis
|
GO:0055080 |
189 |
0.019
|
|
|
|
regulation of ketone biosynthetic process
|
GO:0010566 |
7 |
0.019
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
169 |
0.019
|
|
|
|
cellular homeostasis
|
GO:0019725 |
196 |
0.019
|
|
|
|
positive regulation of rac gtpase activity
|
GO:0032855 |
31 |
0.019
|
|
|
|
chordate embryonic development
|
GO:0043009 |
34 |
0.019
|
|
|
|
neuron projection morphogenesis
|
GO:0048812 |
50 |
0.019
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
408 |
0.019
|
|
|
|
nuclear export
|
GO:0051168 |
69 |
0.019
|
|
|
|
response to hormone
|
GO:0009725 |
175 |
0.019
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
391 |
0.019
|
|
|
|
cellular potassium ion transport
|
GO:0071804 |
60 |
0.019
|
|
|
|
multicellular organismal reproductive process
|
GO:0048609 |
40 |
0.019
|
|
|
|
organelle localization
|
GO:0051640 |
84 |
0.018
|
|
|
|
g1 s transition of mitotic cell cycle
|
GO:0000082 |
78 |
0.018
|
|
|
|
cation transmembrane transport
|
GO:0098655 |
238 |
0.018
|
|
|
|
establishment of organelle localization
|
GO:0051656 |
59 |
0.018
|
|
|
|
salivary gland morphogenesis
|
GO:0007435 |
4 |
0.018
|
|
|
|
aging
|
GO:0007568 |
66 |
0.018
|
|
|
|
embryonic heart tube development
|
GO:0035050 |
9 |
0.018
|
|
|
|
epithelial cell migration
|
GO:0010631 |
119 |
0.018
|
|
|
|
regulation of microtubule cytoskeleton organization
|
GO:0070507 |
61 |
0.018
|
|
|
|
peripheral nervous system development
|
GO:0007422 |
2 |
0.018
|
|
|
|
pericardium development
|
GO:0060039 |
2 |
0.018
|
|
|
|
developmental programmed cell death
|
GO:0010623 |
3 |
0.018
|
|
|
|
regulation of mrna export from nucleus
|
GO:0010793 |
3 |
0.018
|
|
|
|
oxidation reduction process
|
GO:0055114 |
396 |
0.018
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
207 |
0.018
|
|
|
|
positive regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043280 |
69 |
0.017
|
|
|
|
neurogenesis
|
GO:0022008 |
169 |
0.017
|
Fly |
|
|
ribonucleoprotein complex biogenesis
|
GO:0022613 |
116 |
0.017
|
Yeast |
|
|
cell migration involved in gastrulation
|
GO:0042074 |
1 |
0.017
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.017
|
|
|
|
endocytosis
|
GO:0006897 |
159 |
0.017
|
|
|
|
intracellular steroid hormone receptor signaling pathway
|
GO:0030518 |
61 |
0.017
|
|
|
|
negative regulation of smoothened signaling pathway
|
GO:0045879 |
3 |
0.017
|
|
|
|
regulation of lipid metabolic process
|
GO:0019216 |
96 |
0.017
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.017
|
|
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.017
|
|
|
|
positive regulation of endopeptidase activity
|
GO:0010950 |
84 |
0.017
|
|
|
|
nucleic acid transport
|
GO:0050657 |
39 |
0.017
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
207 |
0.017
|
|
|
|
positive regulation of nf kappab transcription factor activity
|
GO:0051092 |
81 |
0.017
|
|
|
|
cellular hormone metabolic process
|
GO:0034754 |
41 |
0.016
|
|
|
|
protein dephosphorylation
|
GO:0006470 |
81 |
0.016
|
|
|
|
regulation of homeostatic process
|
GO:0032844 |
121 |
0.016
|
|
|
|
cardioblast cell fate specification
|
GO:0042685 |
1 |
0.016
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.016
|
|
