Homo sapiens

0 known processes

PNRC1

proline-rich nuclear receptor coactivator 1

(Aliases: PNAS-145,PROL2,PRR2,B4-2)

PNRC1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of endothelial cell differentiation GO:0045601 4 0.165
positive regulation of developmental process GO:0051094 314 0.150
positive regulation of mrna 3 end processing GO:0031442 12 0.140
response to oxygen containing compound GO:1901700 369 0.139
positive regulation of fibroblast apoptotic process GO:2000271 6 0.134
circulatory system development GO:0072359 262 0.121
positive regulation of myoblast differentiation GO:0045663 6 0.116
positive regulation of endothelial cell differentiation GO:0045603 2 0.111
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.102
positive regulation of apoptotic process GO:0043065 246 0.098
cellular response to dna damage stimulus GO:0006974 379 0.096
regulation of striated muscle cell differentiation GO:0051153 25 0.094
positive regulation of mrna metabolic process GO:1903313 19 0.094
cardiovascular system development GO:0072358 262 0.091
regulation of cell differentiation GO:0045595 393 0.087
positive regulation of catabolic process GO:0009896 310 0.083
epithelial cell differentiation GO:0030855 141 0.076
nervous system development GO:0007399 293 0.073
negative regulation of protein metabolic process GO:0051248 391 0.072
fibroblast apoptotic process GO:0044346 8 0.071
regulation of cell cycle GO:0051726 393 0.070
response to hormone GO:0009725 175 0.064
negative regulation of cell proliferation GO:0008285 228 0.063
muscle structure development GO:0061061 98 0.061
positive regulation of cell death GO:0010942 263 0.059
muscle organ development GO:0007517 56 0.059
mrna catabolic process GO:0006402 56 0.058
Human
negative regulation of cell differentiation GO:0045596 171 0.058
positive regulation of cell differentiation GO:0045597 211 0.057
positive regulation of cellular catabolic process GO:0031331 284 0.056
macromolecule methylation GO:0043414 97 0.055
methylation GO:0032259 106 0.055
negative regulation of multicellular organismal process GO:0051241 317 0.053
regulation of mrna catabolic process GO:0061013 13 0.053
protein methylation GO:0006479 74 0.051
blood vessel morphogenesis GO:0048514 162 0.051
protein alkylation GO:0008213 74 0.050
regulation of anatomical structure morphogenesis GO:0022603 286 0.049
negative regulation of cell cycle GO:0045786 193 0.048
mitotic cell cycle GO:0000278 326 0.047
locomotory behavior GO:0007626 1 0.047
mrna 3 end processing GO:0031124 24 0.045
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.043
post embryonic development GO:0009791 2 0.043
regulation of nuclear transcribed mrna catabolic process deadenylation dependent decay GO:1900151 8 0.042
immune system development GO:0002520 195 0.042
cellular response to glucocorticoid stimulus GO:0071385 4 0.042
rna processing GO:0006396 255 0.042
regulation of meiotic cell cycle GO:0051445 4 0.041
metal ion transport GO:0030001 272 0.041
positive regulation of transport GO:0051050 336 0.041
cellular response to lipid GO:0071396 127 0.041
negative regulation of apoptotic process GO:0043066 316 0.041
regulation of muscle organ development GO:0048634 27 0.041
cell development GO:0048468 328 0.041
response to organic cyclic compound GO:0014070 204 0.041
neurogenesis GO:0022008 169 0.039
regulation of cell development GO:0060284 161 0.039
negative regulation of cellular protein metabolic process GO:0032269 353 0.039
muscle tissue development GO:0060537 62 0.039
cellular response to hormone stimulus GO:0032870 125 0.039
regulation of muscle tissue development GO:1901861 26 0.038
response to peptide GO:1901652 65 0.038
cell adhesion GO:0007155 325 0.038
regulation of mitotic cell cycle GO:0007346 189 0.037
negative regulation of mitotic cell cycle GO:0045930 102 0.037
regulation of cytokine production GO:0001817 232 0.037
regulation of mrna metabolic process GO:1903311 53 0.037
response to lipid GO:0033993 206 0.037
nuclear transcribed mrna catabolic process GO:0000956 48 0.036
Human
regulation of mrna processing GO:0050684 48 0.036
regulation of translation GO:0006417 89 0.036
response to abiotic stimulus GO:0009628 336 0.036
cellular response to oxygen containing compound GO:1901701 276 0.035
purine ribonucleoside catabolic process GO:0046130 398 0.035
posttranscriptional regulation of gene expression GO:0010608 213 0.035
negative regulation of catalytic activity GO:0043086 335 0.034
immune response GO:0006955 307 0.034
positive regulation of mrna processing GO:0050685 17 0.034
muscle cell differentiation GO:0042692 63 0.034
translation GO:0006412 132 0.034
negative regulation of cell death GO:0060548 345 0.034
cd4 positive alpha beta t cell differentiation involved in immune response GO:0002294 4 0.033
striated muscle tissue development GO:0014706 59 0.033
potassium ion transport GO:0006813 62 0.033
nucleoside phosphate catabolic process GO:1901292 412 0.032
epithelium development GO:0060429 227 0.032
behavior GO:0007610 112 0.032
apoptotic signaling pathway GO:0097190 268 0.032
cell type specific apoptotic process GO:0097285 125 0.031
regulation of fibroblast apoptotic process GO:2000269 8 0.031
anatomical structure formation involved in morphogenesis GO:0048646 284 0.031
positive regulation of immune system process GO:0002684 283 0.031
regulation of striated muscle tissue development GO:0016202 26 0.031
generation of neurons GO:0048699 152 0.030
rna 3 end processing GO:0031123 35 0.030
negative regulation of developmental process GO:0051093 247 0.030
cd4 positive alpha beta t cell differentiation GO:0043367 4 0.030
positive regulation of programmed cell death GO:0043068 249 0.029
cell projection organization GO:0030030 252 0.029
sex determination GO:0007530 3 0.029
protein catabolic process GO:0030163 325 0.028
multicellular organismal aging GO:0010259 3 0.028
regulation of myotube differentiation GO:0010830 18 0.028
positive regulation of epithelial cell differentiation GO:0030858 14 0.028
regulation of protein transport GO:0051223 213 0.028
regulation of mrna 3 end processing GO:0031440 12 0.027
purine nucleoside triphosphate metabolic process GO:0009144 412 0.027
regulation of cellular response to stress GO:0080135 244 0.027
response to organonitrogen compound GO:0010243 156 0.027
rna catabolic process GO:0006401 71 0.027
Human
cellular amino acid metabolic process GO:0006520 116 0.027
negative regulation of cellular component organization GO:0051129 235 0.026
blood vessel development GO:0001568 172 0.026
regulation of cell cycle process GO:0010564 266 0.026
cytokine mediated signaling pathway GO:0019221 109 0.026
regulation of muscle cell differentiation GO:0051147 31 0.026
nucleoside triphosphate metabolic process GO:0009141 422 0.026
regulation of gtpase activity GO:0043087 180 0.026
negative regulation of phosphorus metabolic process GO:0010563 267 0.026
regulation of neural precursor cell proliferation GO:2000177 4 0.026
ribonucleoside triphosphate catabolic process GO:0009203 391 0.026
regulation of transferase activity GO:0051338 355 0.026
mrna processing GO:0006397 133 0.025
associative learning GO:0008306 1 0.025
positive regulation of phosphorylation GO:0042327 394 0.025
response to nitrogen compound GO:1901698 184 0.025
regeneration GO:0031099 4 0.025
vasculature development GO:0001944 181 0.025
muscle cell development GO:0055001 29 0.025
response to external biotic stimulus GO:0043207 261 0.025
purine ribonucleoside metabolic process GO:0046128 437 0.025
system process GO:0003008 349 0.025
response to cytokine GO:0034097 232 0.025
cellular macromolecule catabolic process GO:0044265 380 0.025
Human
ribonucleoside triphosphate metabolic process GO:0009199 412 0.025
regulation of purine nucleotide metabolic process GO:1900542 264 0.024
positive regulation of mrna catabolic process GO:0061014 10 0.024
response to biotic stimulus GO:0009607 276 0.024
purine ribonucleotide catabolic process GO:0009154 404 0.024
cellular response to endogenous stimulus GO:0071495 336 0.024
myoblast differentiation GO:0045445 21 0.024
rna interference GO:0016246 4 0.024
response to oxidative stress GO:0006979 121 0.024
angiogenesis GO:0001525 147 0.024
regulation of gtp catabolic process GO:0033124 180 0.024
glycosyl compound catabolic process GO:1901658 413 0.024
regulation of myoblast differentiation GO:0045661 12 0.024
positive regulation of interleukin 5 production GO:0032754 3 0.024
positive regulation of nucleotide metabolic process GO:0045981 230 0.023
positive regulation of nuclear transcribed mrna poly a tail shortening GO:0060213 8 0.023
purine nucleoside triphosphate catabolic process GO:0009146 392 0.023
carbohydrate derivative biosynthetic process GO:1901137 207 0.023
cytokine production GO:0001816 247 0.023
neuron projection development GO:0031175 106 0.023
negative regulation of programmed cell death GO:0043069 321 0.023
morphogenesis of embryonic epithelium GO:0016331 4 0.023
negative regulation of intracellular signal transduction GO:1902532 183 0.022
negative regulation of protein modification process GO:0031400 200 0.022
reproductive process GO:0022414 106 0.022
segmentation GO:0035282 4 0.022
mapk cascade GO:0000165 288 0.022
protein modification by small protein conjugation GO:0032446 342 0.022
organophosphate catabolic process GO:0046434 430 0.022
rho protein signal transduction GO:0007266 26 0.021
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.021
negative regulation of phosphate metabolic process GO:0045936 267 0.021
regulation of nuclear transcribed mrna poly a tail shortening GO:0060211 8 0.021
positive regulation of ion transport GO:0043270 87 0.021
amine metabolic process GO:0009308 44 0.021
negative regulation of cell cycle process GO:0010948 121 0.021
tissue regeneration GO:0042246 3 0.021
limbic system development GO:0021761 3 0.021
regulation of vasculature development GO:1901342 97 0.021
neuron differentiation GO:0030182 138 0.021
endothelium development GO:0003158 33 0.021
gtp metabolic process GO:0046039 239 0.021
striated muscle cell differentiation GO:0051146 43 0.020
nucleoside catabolic process GO:0009164 408 0.020
positive regulation of muscle cell differentiation GO:0051149 15 0.020
biological adhesion GO:0022610 331 0.020
signal transduction by phosphorylation GO:0023014 297 0.020
response to endoplasmic reticulum stress GO:0034976 49 0.020
purine containing compound catabolic process GO:0072523 411 0.020
nucleotide catabolic process GO:0009166 408 0.020
hemopoiesis GO:0030097 180 0.020
reactive oxygen species metabolic process GO:0072593 75 0.020
mitotic cell cycle phase transition GO:0044772 162 0.020
determination of adult lifespan GO:0008340 2 0.020
prostate gland development GO:0030850 3 0.020
regulation of nucleotide metabolic process GO:0006140 269 0.019
organ morphogenesis GO:0009887 147 0.019
single organism carbohydrate metabolic process GO:0044723 193 0.019
peripheral nervous system development GO:0007422 2 0.019
skeletal muscle fiber development GO:0048741 12 0.019
regulation of cell migration GO:0030334 289 0.019
cation transport GO:0006812 331 0.019
cellular response to biotic stimulus GO:0071216 71 0.018
negative regulation of phosphorylation GO:0042326 174 0.018
regulation of carbohydrate metabolic process GO:0006109 54 0.018
regulation of nucleotide catabolic process GO:0030811 205 0.018
neuron development GO:0048666 113 0.018
protein ubiquitination GO:0016567 314 0.018
cellular response to cytokine stimulus GO:0071345 181 0.018
positive regulation of nuclear transcribed mrna catabolic process deadenylation dependent decay GO:1900153 8 0.018
myeloid cell differentiation GO:0030099 117 0.018
hippocampus development GO:0021766 1 0.018
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.017
regulation of angiogenesis GO:0045765 92 0.017
cranial nerve morphogenesis GO:0021602 1 0.017
neural tube closure GO:0001843 3 0.017
regulation of ras gtpase activity GO:0032318 128 0.017
regulation of response to external stimulus GO:0032101 222 0.017
positive regulation of meiotic cell cycle GO:0051446 2 0.017
positive regulation of angiogenesis GO:0045766 51 0.017
negative regulation of neural precursor cell proliferation GO:2000178 1 0.017
neural tube formation GO:0001841 3 0.017
response to virus GO:0009615 126 0.017
monovalent inorganic cation transport GO:0015672 128 0.017
negative regulation of immune system process GO:0002683 136 0.017
regulation of male gonad development GO:2000018 4 0.017
hindbrain development GO:0030902 3 0.017
negative regulation of type 2 immune response GO:0002829 3 0.017
purine nucleoside catabolic process GO:0006152 398 0.017
myotube differentiation GO:0014902 22 0.017
regulation of purine nucleotide catabolic process GO:0033121 205 0.016
mrna metabolic process GO:0016071 175 0.016
Human
blastoderm segmentation GO:0007350 2 0.016
hematopoietic or lymphoid organ development GO:0048534 186 0.016
regulation of defense response GO:0031347 154 0.016
nucleocytoplasmic transport GO:0006913 176 0.016
regulation of protein catabolic process GO:0042176 155 0.016
dephosphorylation GO:0016311 209 0.016
negative regulation of hydrolase activity GO:0051346 182 0.016
negative regulation of cellular amine metabolic process GO:0033239 3 0.016
regulation of skeletal muscle tissue development GO:0048641 15 0.016
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.016
actin filament based process GO:0030029 224 0.016
brain development GO:0007420 97 0.016
nuclear transport GO:0051169 179 0.015
positive regulation of cellular amine metabolic process GO:0033240 7 0.015
ras protein signal transduction GO:0007265 73 0.015
regulation of apoptotic signaling pathway GO:2001233 175 0.015
intracellular receptor signaling pathway GO:0030522 104 0.015
modification dependent macromolecule catabolic process GO:0043632 212 0.015
regulation of leukocyte activation GO:0002694 115 0.015
embryonic camera type eye development GO:0031076 2 0.015
intrinsic apoptotic signaling pathway GO:0097193 127 0.015
nucleoside triphosphate catabolic process GO:0009143 394 0.015
midgut development GO:0007494 1 0.015
positive regulation of protein transport GO:0051222 135 0.015
positive regulation of cell cycle GO:0045787 140 0.015
regulation of immune response GO:0050776 201 0.015
embryonic epithelial tube formation GO:0001838 4 0.015
primary neural tube formation GO:0014020 3 0.015
regulation of protein localization GO:0032880 296 0.015
neurological system process GO:0050877 163 0.015
positive regulation of organic acid transport GO:0032892 3 0.015
organonitrogen compound biosynthetic process GO:1901566 200 0.014
regulation of skeletal muscle fiber development GO:0048742 12 0.014
cellular ketone metabolic process GO:0042180 80 0.014
meiosis i GO:0007127 4 0.014
neuron apoptotic process GO:0051402 39 0.014
response to peptide hormone GO:0043434 61 0.014
syncytium formation by plasma membrane fusion GO:0000768 2 0.014
negative regulation of cell cycle phase transition GO:1901988 89 0.014
protein localization to organelle GO:0033365 280 0.014
single organism reproductive process GO:0044702 98 0.014
regulation of intracellular transport GO:0032386 195 0.014
regulation of inflammatory response GO:0050727 46 0.014
purine nucleotide catabolic process GO:0006195 405 0.014
regulation of establishment of protein localization GO:0070201 242 0.014
cell growth GO:0016049 160 0.014
positive regulation of intracellular transport GO:0032388 104 0.014
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.013
regulation of cell activation GO:0050865 125 0.013
positive regulation of organelle organization GO:0010638 195 0.013
positive regulation of nucleoside metabolic process GO:0045979 186 0.013
cellular amine metabolic process GO:0044106 41 0.013
cellular macromolecular complex assembly GO:0034622 324 0.013
ribonucleotide catabolic process GO:0009261 405 0.013
immune effector process GO:0002252 159 0.013
regulation of dna metabolic process GO:0051052 153 0.013
female gamete generation GO:0007292 2 0.013
regulation of metal ion transport GO:0010959 120 0.013
cell morphogenesis GO:0000902 296 0.013
tube closure GO:0060606 3 0.013
positive regulation of ras gtpase activity GO:0032320 117 0.013
response to electrical stimulus GO:0051602 1 0.013
thymus development GO:0048538 3 0.013
defense response GO:0006952 315 0.013
anterior posterior axis specification embryo GO:0008595 2 0.013
cyclic nucleotide metabolic process GO:0009187 82 0.013
muscle fiber development GO:0048747 16 0.013
oogenesis GO:0048477 2 0.013
striated muscle cell development GO:0055002 27 0.013
response to other organism GO:0051707 261 0.013
ribonucleoside catabolic process GO:0042454 406 0.013
t helper cell differentiation GO:0042093 4 0.013
t cell activation GO:0042110 99 0.013
growth GO:0040007 202 0.013
positive regulation of cell proliferation GO:0008284 301 0.013
establishment of planar polarity GO:0001736 3 0.013
t cell differentiation in thymus GO:0033077 4 0.013
negative regulation of translation GO:0017148 37 0.013
regulation of cell adhesion GO:0030155 166 0.013
cellular response to organic cyclic compound GO:0071407 127 0.012
regulation of nucleoside metabolic process GO:0009118 209 0.012
guanosine containing compound metabolic process GO:1901068 244 0.012
response to ionizing radiation GO:0010212 65 0.012
rab protein signal transduction GO:0032482 4 0.012
regulation of cellular amino acid metabolic process GO:0006521 6 0.012
cellular carbohydrate metabolic process GO:0044262 84 0.012
regulation of synaptic plasticity GO:0048167 3 0.012
regulation of protein maturation GO:1903317 150 0.012
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.012
positive regulation of hydrolase activity GO:0051345 331 0.012
glycoprotein metabolic process GO:0009100 110 0.012
heart development GO:0007507 95 0.012
nuclear transcribed mrna catabolic process deadenylation dependent decay GO:0000288 14 0.012
negative regulation of protein processing GO:0010955 142 0.012
regulation of ion transport GO:0043269 189 0.012
digestive tract development GO:0048565 75 0.012
intracellular protein transport GO:0006886 270 0.012
negative regulation of organelle organization GO:0010639 126 0.012
vasodilation GO:0042311 4 0.012
nucleoside phosphate biosynthetic process GO:1901293 109 0.012
adult locomotory behavior GO:0008344 1 0.012
i kappab kinase nf kappab signaling GO:0007249 166 0.012
positive regulation of cellular component movement GO:0051272 181 0.012
negative regulation of intrinsic apoptotic signaling pathway GO:2001243 40 0.012
regulation of immune effector process GO:0002697 91 0.012
central nervous system development GO:0007417 123 0.012
positive regulation of kinase activity GO:0033674 204 0.012
regulation of blood circulation GO:1903522 59 0.012
activation of immune response GO:0002253 114 0.012
embryo development GO:0009790 123 0.012
organ formation GO:0048645 3 0.012
cellular response to oxidative stress GO:0034599 85 0.012
inflammatory response GO:0006954 79 0.011
cerebellum development GO:0021549 2 0.011
wnt signaling pathway GO:0016055 156 0.011
heart process GO:0003015 62 0.011
regulation of membrane potential GO:0042391 95 0.011
negative regulation of transferase activity GO:0051348 124 0.011
cell division GO:0051301 168 0.011
response to mechanical stimulus GO:0009612 51 0.011
g1 s transition of mitotic cell cycle GO:0000082 78 0.011
morphogenesis of a polarized epithelium GO:0001738 3 0.011
signal transduction by p53 class mediator GO:0072331 72 0.011
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.011
t cell differentiation GO:0030217 29 0.011
negative regulation of protein maturation GO:1903318 142 0.011
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.011
cytoplasmic transport GO:0016482 379 0.011
positive regulation of gtp catabolic process GO:0033126 166 0.011
single organism membrane organization GO:0044802 268 0.011
protein localization to nucleus GO:0034504 136 0.011
regulation of kinase activity GO:0043549 314 0.011
regulation of secretion GO:0051046 194 0.011
microtubule cytoskeleton organization GO:0000226 176 0.011
positive regulation of cytokine production GO:0001819 167 0.011
mitochondrial transport GO:0006839 60 0.011
regulation of t cell activation GO:0050863 77 0.011
regulation of glial cell proliferation GO:0060251 4 0.011
motor neuron axon guidance GO:0008045 2 0.011
membrane organization GO:0061024 292 0.011
lipid metabolic process GO:0006629 381 0.011
regulation of t helper cell differentiation GO:0045622 3 0.011
regulation of cellular amine metabolic process GO:0033238 11 0.011
cardiac muscle cell contraction GO:0086003 4 0.011
positive regulation of immune response GO:0050778 159 0.011
nuclear division GO:0000280 128 0.011
regulation of fibroblast proliferation GO:0048145 32 0.011
maintenance of location GO:0051235 112 0.011
cell migration involved in gastrulation GO:0042074 1 0.011
leukocyte activation GO:0045321 164 0.011
actin filament based movement GO:0030048 17 0.011
cell substrate adhesion GO:0031589 132 0.011
regulation of cellular ketone metabolic process GO:0010565 50 0.011
single organism cellular localization GO:1902580 332 0.011
camp metabolic process GO:0046058 61 0.011
skeletal muscle organ development GO:0060538 26 0.011
negative regulation of neuron apoptotic process GO:0043524 23 0.011
regulation of mapk cascade GO:0043408 262 0.011
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.011
reproduction GO:0000003 63 0.011
reactive nitrogen species metabolic process GO:2001057 3 0.011
response to steroid hormone GO:0048545 80 0.010
epithelial cell proliferation GO:0050673 128 0.010
regulation of cytoskeleton organization GO:0051493 177 0.010
spermatid development GO:0007286 4 0.010
positive regulation of transferase activity GO:0051347 227 0.010
enzyme linked receptor protein signaling pathway GO:0007167 303 0.010
positive regulation of male gonad development GO:2000020 3 0.010
regulation of reactive oxygen species metabolic process GO:2000377 41 0.010
regulation of intrinsic apoptotic signaling pathway GO:2001242 72 0.010
positive regulation of cellular component biogenesis GO:0044089 158 0.010
regulation of potassium ion transport GO:0043266 24 0.010
small gtpase mediated signal transduction GO:0007264 78 0.010
cellular component morphogenesis GO:0032989 314 0.010
spermatid differentiation GO:0048515 4 0.010
pattern specification process GO:0007389 43 0.010
tissue morphogenesis GO:0048729 96 0.010
cellular response to steroid hormone stimulus GO:0071383 37 0.010
forebrain generation of neurons GO:0021872 3 0.010
regulation of cell division GO:0051302 116 0.010
nerve development GO:0021675 4 0.010
heart contraction GO:0060047 62 0.010
circadian behavior GO:0048512 2 0.010
nucleic acid phosphodiester bond hydrolysis GO:0090305 102 0.010
regulation of microtubule based process GO:0032886 74 0.010
response to oxygen levels GO:0070482 100 0.010
organophosphate biosynthetic process GO:0090407 163 0.010
outflow tract septum morphogenesis GO:0003148 4 0.010
memory GO:0007613 3 0.010

PNRC1 disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 295 0.054
cancer DOID:162 167 0.045
disease of cellular proliferation DOID:14566 174 0.045
organ system cancer DOID:0050686 164 0.032
inherited metabolic disorder DOID:655 242 0.021
nervous system disease DOID:863 431 0.015
neuropathy DOID:870 52 0.015
cardiovascular system disease DOID:1287 106 0.015
sensory system disease DOID:0050155 203 0.013
acquired metabolic disease DOID:0060158 58 0.011
amino acid metabolic disorder DOID:9252 50 0.010