IMP

Process View

Homo sapiens

3 genes annotated in human

Multi-species View

positive regulation of male gonad development

GO:2000020

Any process that activates or increases the frequency, rate or extent of male gonad development.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "positive regulation of male gonad development"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "positive regulation of male gonad development" (in gray)

Name	Description	Probability	Func Analog Organism
POU3F2	POU class 3 homeobox 2	0.999
PAX3	paired box 3	0.998
SMAD7	SMAD family member 7	0.960
PROX1	prospero homeobox 1	0.908
POU5F1	POU class 5 homeobox 1	0.827
WWP2	WW domain containing E3 ubiquitin protein ligase 2	0.656
HIPK2	homeodomain interacting protein kinase 2	0.559
FOXD3	forkhead box D3	0.471
MARCKSL1	MARCKS-like 1	0.417
EP300	E1A binding protein p300	0.367
DVL3	dishevelled, dsh homolog 3 (Drosophila)	0.356
TFAP2C	transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)	0.353
HNF4A	hepatocyte nuclear factor 4, alpha	0.311
TFAP2A	transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)	0.254
ZNF205	zinc finger protein 205	0.212
SOX9	SRY (sex determining region Y)-box 9	0.199
CXXC5	CXXC finger protein 5	0.169
SALL2	sal-like 2 (Drosophila)	0.160
UBE2I	ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast)	0.158
NR0B1	nuclear receptor subfamily 0, group B, member 1	0.151
GATA4	GATA binding protein 4	0.115
SOX11	SRY (sex determining region Y)-box 11	0.085	Human
SLC9A3R2	solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2	0.071
FOXG1	forkhead box G1	0.059
TAOK1	TAO kinase 1	0.058
NR5A1	nuclear receptor subfamily 5, group A, member 1	0.049
PAX6	paired box 6	0.048
TBX2	T-box 2	0.047
ELK1	ELK1, member of ETS oncogene family	0.045
DVL1	dishevelled, dsh homolog 1 (Drosophila)	0.044
NR0B2	nuclear receptor subfamily 0, group B, member 2	0.040
FOXC2	forkhead box C2 (MFH-1, mesenchyme forkhead 1)	0.039
COL2A1	collagen, type II, alpha 1	0.036
BCL11A	B-cell CLL/lymphoma 11A (zinc finger protein)	0.033
INHBB	inhibin, beta B	0.032
SOX5	SRY (sex determining region Y)-box 5	0.032
EFNB3	ephrin-B3	0.031
POU3F3	POU class 3 homeobox 3	0.031
NPM3	nucleophosmin/nucleoplasmin 3	0.030
MSX1	msh homeobox 1	0.030
TTYH1	tweety homolog 1 (Drosophila)	0.030
ZIC3	Zic family member 3 (odd-paired homolog, Drosophila)	0.030
SALL3	sal-like 3 (Drosophila)	0.029
OLIG2	oligodendrocyte lineage transcription factor 2	0.028
WT1	Wilms tumor 1	0.027	Mouse
SOX21	SRY (sex determining region Y)-box 21	0.027
SOX1	SRY (sex determining region Y)-box 1	0.026	Human
FOXC1	forkhead box C1	0.026
POU3F1	POU class 3 homeobox 1	0.025
NKX2-5	NK2 transcription factor related, locus 5 (Drosophila)	0.025
ST8SIA2	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2	0.025
BRD3	bromodomain containing 3	0.024
PPARGC1A	peroxisome proliferator-activated receptor gamma, coactivator 1 alpha	0.024
CEP164	centrosomal protein 164kDa	0.024
HOXD3	homeobox D3	0.023
HOXD13	homeobox D13	0.023
MMP16	matrix metallopeptidase 16 (membrane-inserted)	0.022
BMP7	bone morphogenetic protein 7	0.021
MDK	midkine (neurite growth-promoting factor 2)	0.020
JAM2	junctional adhesion molecule 2	0.020
FABP7	fatty acid binding protein 7, brain	0.020
ZNF653	zinc finger protein 653	0.020
PCDH17	protocadherin 17	0.020
ZFHX4	zinc finger homeobox 4	0.019
HOXB13	homeobox B13	0.018
HMGA2	high mobility group AT-hook 2	0.018
SIM2	single-minded homolog 2 (Drosophila)	0.018
SOX18	SRY (sex determining region Y)-box 18	0.018	Human
C1QL1	complement component 1, q subcomponent-like 1	0.018
ASCL1	achaete-scute complex homolog 1 (Drosophila)	0.018
FGD1	FYVE, RhoGEF and PH domain containing 1	0.016
SRM	spermidine synthase	0.016
CLDN5	claudin 5	0.016
ID4	inhibitor of DNA binding 4, dominant negative helix-loop-helix protein	0.016
TGIF2	TGFB-induced factor homeobox 2	0.015
NR2F1	nuclear receptor subfamily 2, group F, member 1	0.015
MUL1	mitochondrial E3 ubiquitin protein ligase 1	0.015
SOX8	SRY (sex determining region Y)-box 8	0.015	Human
EFNB2	ephrin-B2	0.015
SIX3	SIX homeobox 3	0.015
SOX3	SRY (sex determining region Y)-box 3	0.015	Human
CDH5	cadherin 5, type 2 (vascular endothelium)	0.015
TBX1	T-box 1	0.015
CTNND2	catenin (cadherin-associated protein), delta 2 (neural plakophilin-related arm-repeat protein)	0.015
POU4F1	POU class 4 homeobox 1	0.015
ZNF536	zinc finger protein 536	0.015
CNOT4	CCR4-NOT transcription complex, subunit 4	0.014
SALL1	sal-like 1 (Drosophila)	0.014
MSI1	musashi homolog 1 (Drosophila)	0.014
OTP	orthopedia homeobox	0.014
CADM4	cell adhesion molecule 4	0.014
CAPN6	calpain 6	0.014
NOVA2	neuro-oncological ventral antigen 2	0.014
KDM5B	lysine (K)-specific demethylase 5B	0.013
FOXF1	forkhead box F1	0.013
MPL	myeloproliferative leukemia virus oncogene	0.013
SMO	smoothened homolog (Drosophila)	0.013
SOX2	SRY (sex determining region Y)-box 2	0.013	Human
FOXD1	forkhead box D1	0.013
SIX2	SIX homeobox 2	0.013
TAL1	T-cell acute lymphocytic leukemia 1	0.013
FAM19A5	family with sequence similarity 19 (chemokine (C-C motif)-like), member A5	0.013
SOX10	SRY (sex determining region Y)-box 10	0.012	Human
GJB3	gap junction protein, beta 3, 31kDa	0.012
NFIX	nuclear factor I/X (CCAAT-binding transcription factor)	0.012
GATA5	GATA binding protein 5	0.012
DBN1	drebrin 1	0.012
TCF3	transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)	0.012
PPFIA3	protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3	0.012
MEF2C	myocyte enhancer factor 2C	0.012
DUSP1	dual specificity phosphatase 1	0.012
ZNF444	zinc finger protein 444	0.012
POU2F3	POU class 2 homeobox 3	0.012
NR2F2	nuclear receptor subfamily 2, group F, member 2	0.012
VGLL4	vestigial like 4 (Drosophila)	0.012
RAMP2	receptor (G protein-coupled) activity modifying protein 2	0.012
TBX5	T-box 5	0.012
ZIC1	Zic family member 1 (odd-paired homolog, Drosophila)	0.012
LHX2	LIM homeobox 2	0.012
HOXD1	homeobox D1	0.012
HES5	hairy and enhancer of split 5 (Drosophila)	0.011
SREBF2	sterol regulatory element binding transcription factor 2	0.011
EN1	engrailed homeobox 1	0.011
NKX2-2	NK2 homeobox 2	0.011
MEX3B	mex-3 homolog B (C. elegans)	0.011
TFAP2B	transcription factor AP-2 beta (activating enhancer binding protein 2 beta)	0.011
NRTN	neurturin	0.011
IRX5	iroquois homeobox 5	0.011
TIE1	tyrosine kinase with immunoglobulin-like and EGF-like domains 1	0.011
FAT1	FAT tumor suppressor homolog 1 (Drosophila)	0.011
GBX2	gastrulation brain homeobox 2	0.011
FUT1	fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group)	0.011
PCDH10	protocadherin 10	0.011
SHH	sonic hedgehog	0.011
CTBP2	C-terminal binding protein 2	0.011
DAXX	death-domain associated protein	0.011
PTCH1	patched 1	0.011
SMAD5	SMAD family member 5	0.011
GDNF	glial cell derived neurotrophic factor	0.011
SOX4	SRY (sex determining region Y)-box 4	0.011	Human
FZD7	frizzled homolog 7 (Drosophila)	0.011
JUND	jun D proto-oncogene	0.011
CDH3	cadherin 3, type 1, P-cadherin (placental)	0.010
FOXE1	forkhead box E1 (thyroid transcription factor 2)	0.010
CDKN1C	cyclin-dependent kinase inhibitor 1C (p57, Kip2)	0.010
PNRC1	proline-rich nuclear receptor coactivator 1	0.010
HS3ST1	heparan sulfate (glucosamine) 3-O-sulfotransferase 1	0.010
NEUROG1	neurogenin 1	0.010
GABRB3	gamma-aminobutyric acid (GABA) A receptor, beta 3	0.010
NRXN2	neurexin 2	0.010
ETV3	ets variant 3	0.010
RORA	RAR-related orphan receptor A	0.010