|
|
endodermal cell fate commitment
|
GO:0001711 |
4 |
0.925
|
Zebrafish |
|
|
pituitary gland development
|
GO:0021983 |
2 |
0.900
|
|
|
|
somatic stem cell maintenance
|
GO:0035019 |
4 |
0.877
|
Mouse |
|
|
regulation of canonical wnt signaling pathway
|
GO:0060828 |
88 |
0.845
|
|
|
|
epithelium development
|
GO:0060429 |
227 |
0.813
|
Human Zebrafish Mouse Fly |
|
|
negative regulation of gliogenesis
|
GO:0014014 |
3 |
0.797
|
|
|
|
canonical wnt signaling pathway
|
GO:0060070 |
116 |
0.780
|
|
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
4 |
0.769
|
Mouse |
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.754
|
|
|
|
endodermal cell fate specification
|
GO:0001714 |
4 |
0.753
|
Zebrafish |
|
|
cell development
|
GO:0048468 |
328 |
0.684
|
|
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.677
|
Human Zebrafish Mouse |
|
|
cardiovascular system development
|
GO:0072358 |
262 |
0.642
|
|
|
|
organ morphogenesis
|
GO:0009887 |
147 |
0.634
|
Zebrafish Mouse Fly |
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.596
|
Human |
|
|
urogenital system development
|
GO:0001655 |
65 |
0.586
|
|
|
|
positive regulation of epithelial cell proliferation
|
GO:0050679 |
65 |
0.562
|
Human |
|
|
regulation of glomerulus development
|
GO:0090192 |
3 |
0.560
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.557
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
156 |
0.543
|
|
|
|
epithelial tube morphogenesis
|
GO:0060562 |
38 |
0.542
|
Human Zebrafish Mouse |
|
|
regulation of branching involved in ureteric bud morphogenesis
|
GO:0090189 |
3 |
0.533
|
|
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
144 |
0.529
|
Mouse |
|
|
spinal cord development
|
GO:0021510 |
4 |
0.529
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.512
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.511
|
Human |
|
|
organ formation
|
GO:0048645 |
3 |
0.501
|
Mouse |
|
|
circulatory system development
|
GO:0072359 |
262 |
0.500
|
|
|
|
tube morphogenesis
|
GO:0035239 |
95 |
0.499
|
Human Zebrafish Mouse |
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.495
|
|
|
|
astrocyte differentiation
|
GO:0048708 |
4 |
0.482
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.476
|
|
|
|
regulation of cell development
|
GO:0060284 |
161 |
0.469
|
|
|
|
mesonephric tubule formation
|
GO:0072172 |
1 |
0.469
|
|
|
|
morphogenesis of an epithelium
|
GO:0002009 |
60 |
0.468
|
Human Zebrafish Mouse |
|
|
kidney morphogenesis
|
GO:0060993 |
19 |
0.464
|
Mouse |
|
|
embryonic morphogenesis
|
GO:0048598 |
85 |
0.463
|
Human Zebrafish Mouse |
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.459
|
|
|
|
endoderm development
|
GO:0007492 |
33 |
0.449
|
Human Zebrafish |
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.445
|
|
|
|
mesenchymal cell development
|
GO:0014031 |
50 |
0.438
|
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.433
|
|
|
|
prostate gland morphogenesis
|
GO:0060512 |
1 |
0.433
|
Mouse |
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.428
|
|
|
|
tube development
|
GO:0035295 |
125 |
0.424
|
Human Zebrafish Mouse |
|
|
negative regulation of wnt signaling pathway
|
GO:0030178 |
69 |
0.422
|
|
|
|
chemotaxis
|
GO:0006935 |
157 |
0.406
|
Mouse |
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.404
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
125 |
0.394
|
|
|
|
osteoblast differentiation
|
GO:0001649 |
92 |
0.394
|
|
|
|
taxis
|
GO:0042330 |
157 |
0.393
|
Mouse |
|
|
response to growth factor
|
GO:0070848 |
205 |
0.392
|
Human |
|
|
formation of primary germ layer
|
GO:0001704 |
42 |
0.388
|
Human Zebrafish Mouse |
|
|
negative regulation of canonical wnt signaling pathway
|
GO:0090090 |
55 |
0.385
|
|
|
|
epithelial cell differentiation
|
GO:0030855 |
141 |
0.383
|
Human Mouse Fly |
|
|
embryonic epithelial tube formation
|
GO:0001838 |
4 |
0.382
|
|
|
|
motor neuron axon guidance
|
GO:0008045 |
2 |
0.374
|
|
|
|
generation of neurons
|
GO:0048699 |
152 |
0.359
|
|
|
|
skeletal system development
|
GO:0001501 |
79 |
0.358
|
Mouse |
|
|
digestive system development
|
GO:0055123 |
75 |
0.355
|
Human Zebrafish Mouse |
|
|
stem cell differentiation
|
GO:0048863 |
93 |
0.349
|
|
|
|
negative regulation of cell development
|
GO:0010721 |
48 |
0.347
|
|
|
|
mesonephros development
|
GO:0001823 |
17 |
0.346
|
|
|
|
neuron fate commitment
|
GO:0048663 |
2 |
0.341
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.329
|
|
|
|
connective tissue development
|
GO:0061448 |
39 |
0.324
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.323
|
|
|
|
endodermal cell differentiation
|
GO:0035987 |
31 |
0.321
|
Human Zebrafish |
|
|
tissue morphogenesis
|
GO:0048729 |
96 |
0.317
|
Human Zebrafish Mouse |
|
|
hindbrain development
|
GO:0030902 |
3 |
0.311
|
|
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.307
|
Human |
|
|
regulation of ossification
|
GO:0030278 |
58 |
0.307
|
|
|
|
neural tube formation
|
GO:0001841 |
3 |
0.297
|
|
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.293
|
Human |
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.281
|
|
|
|
regulation of osteoblast differentiation
|
GO:0045667 |
38 |
0.279
|
|
|
|
negative regulation of striated muscle tissue development
|
GO:0045843 |
11 |
0.277
|
|
|
|
negative regulation of cell fate specification
|
GO:0009996 |
3 |
0.267
|
Zebrafish |
|
|
endoderm formation
|
GO:0001706 |
33 |
0.264
|
Human Zebrafish |
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.264
|
Human Zebrafish Mouse |
|
|
ossification
|
GO:0001503 |
121 |
0.255
|
|
|
|
negative regulation of cell differentiation
|
GO:0045596 |
171 |
0.249
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
113 |
0.249
|
Human |
|
|
cell projection organization
|
GO:0030030 |
252 |
0.249
|
|
|
|
negative regulation of embryonic development
|
GO:0045992 |
4 |
0.243
|
Zebrafish Mouse |
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.238
|
Human |
|
|
central nervous system development
|
GO:0007417 |
123 |
0.231
|
|
|
|
cell fate commitment involved in formation of primary germ layer
|
GO:0060795 |
6 |
0.230
|
Zebrafish |
|
|
brain development
|
GO:0007420 |
97 |
0.228
|
|
|
|
negative regulation of gastrulation
|
GO:2000542 |
4 |
0.227
|
Zebrafish |
|
|
neurogenesis
|
GO:0022008 |
169 |
0.222
|
|
|
|
appendage morphogenesis
|
GO:0035107 |
16 |
0.222
|
Mouse Fly |
|
|
epithelial cell proliferation
|
GO:0050673 |
128 |
0.221
|
Human |
|
|
regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090092 |
90 |
0.221
|
|
|
|
forebrain development
|
GO:0030900 |
26 |
0.214
|
|
|
|
negative regulation of transcription from rna polymerase ii promoter
|
GO:0000122 |
281 |
0.212
|
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.211
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.209
|
Mouse Rat |
|
|
prostate gland development
|
GO:0030850 |
3 |
0.207
|
Mouse |
|
|
negative regulation of growth
|
GO:0045926 |
97 |
0.207
|
Human |
|
|
embryonic skeletal joint development
|
GO:0072498 |
2 |
0.206
|
Mouse |
|
|
cartilage development
|
GO:0051216 |
31 |
0.201
|
|
|
|
nephron tubule formation
|
GO:0072079 |
1 |
0.199
|
|
|
|
mesonephric tubule development
|
GO:0072164 |
14 |
0.198
|
Mouse |
|
|
neuron development
|
GO:0048666 |
113 |
0.196
|
|
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.187
|
Human |
|
|
mesenchyme development
|
GO:0060485 |
59 |
0.185
|
|
|
|
skeletal system morphogenesis
|
GO:0048705 |
24 |
0.185
|
Mouse |
|
|
regulation of growth
|
GO:0040008 |
165 |
0.184
|
Human Fly |
|
|
system process
|
GO:0003008 |
349 |
0.180
|
Human |
|
|
mesonephric epithelium development
|
GO:0072163 |
14 |
0.180
|
Mouse |
|
|
gastrulation
|
GO:0007369 |
51 |
0.179
|
Human Zebrafish Mouse |
|
|
ureteric bud development
|
GO:0001657 |
13 |
0.179
|
Mouse |
|
|
regulation of astrocyte differentiation
|
GO:0048710 |
3 |
0.176
|
|
|
|
regulation of nervous system development
|
GO:0051960 |
88 |
0.167
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.167
|
|
|
|
growth
|
GO:0040007 |
202 |
0.163
|
Human Fly |
|
|
embryonic skeletal joint morphogenesis
|
GO:0060272 |
2 |
0.163
|
Mouse |
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.163
|
Human |
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.162
|
|
|
|
cell projection morphogenesis
|
GO:0048858 |
129 |
0.160
|
|
|
|
digestive tract development
|
GO:0048565 |
75 |
0.159
|
Human Zebrafish Mouse |
|
|
digestive tract morphogenesis
|
GO:0048546 |
56 |
0.159
|
Human Zebrafish Mouse |
|
|
regionalization
|
GO:0003002 |
29 |
0.159
|
Zebrafish Fly |
|
|
heart development
|
GO:0007507 |
95 |
0.157
|
Zebrafish |
|
|
canonical wnt signaling pathway involved in mesenchymal stem cell differentiation
|
GO:0044338 |
2 |
0.157
|
|
|
|
branching morphogenesis of an epithelial tube
|
GO:0048754 |
19 |
0.156
|
Human Mouse |
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.156
|
|
|
|
head development
|
GO:0060322 |
108 |
0.151
|
|
|
|
ureteric bud formation
|
GO:0060676 |
1 |
0.149
|
|
|
|
neuron projection development
|
GO:0031175 |
106 |
0.148
|
|
|
|
endothelial cell migration
|
GO:0043542 |
86 |
0.147
|
Human |
|
|
morphogenesis of a branching structure
|
GO:0001763 |
21 |
0.147
|
Human Mouse |
|
|
negative regulation of cell migration
|
GO:0030336 |
102 |
0.145
|
Human |
|
|
gland development
|
GO:0048732 |
48 |
0.144
|
Mouse |
|
|
regulation of mesonephros development
|
GO:0061217 |
3 |
0.144
|
|
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.144
|
Rat |
|
|
primary neural tube formation
|
GO:0014020 |
3 |
0.143
|
|
|
|
cell fate determination
|
GO:0001709 |
3 |
0.143
|
|
|
|
kidney epithelium development
|
GO:0072073 |
25 |
0.143
|
Mouse |
|
|
positive regulation of epithelial cell proliferation involved in wound healing
|
GO:0060054 |
3 |
0.143
|
|
|
|
negative regulation of neurogenesis
|
GO:0050768 |
26 |
0.143
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.143
|
|
|
|
actin filament based process
|
GO:0030029 |
224 |
0.140
|
Human |
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.139
|
|
|
|
regulation of glial cell differentiation
|
GO:0045685 |
3 |
0.138
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.138
|
Fly |
|
|
vasculature development
|
GO:0001944 |
181 |
0.133
|
|
|
|
canonical wnt signaling pathway involved in osteoblast differentiation
|
GO:0044339 |
2 |
0.129
|
|
|
|
stem cell development
|
GO:0048864 |
69 |
0.127
|
Mouse |
|
|
forebrain regionalization
|
GO:0021871 |
3 |
0.127
|
|
|
|
regulation of heart growth
|
GO:0060420 |
4 |
0.126
|
|
|
|
cell fate commitment
|
GO:0045165 |
27 |
0.122
|
Zebrafish |
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.120
|
|
|
|
cardiac cell fate determination
|
GO:0060913 |
3 |
0.120
|
|
|
|
epithelial to mesenchymal transition
|
GO:0001837 |
48 |
0.120
|
|
|
|
morphogenesis of a branching epithelium
|
GO:0061138 |
20 |
0.118
|
Human Mouse |
|
|
neuron projection morphogenesis
|
GO:0048812 |
50 |
0.115
|
|
|
|
nephron development
|
GO:0072006 |
30 |
0.115
|
|
|
|
cell part morphogenesis
|
GO:0032990 |
137 |
0.114
|
|
|
|
non canonical wnt signaling pathway via mapk cascade
|
GO:0038030 |
4 |
0.112
|
|
|
|
response to wounding
|
GO:0009611 |
168 |
0.111
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.110
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.110
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.110
|
|
|
|
cell adhesion
|
GO:0007155 |
325 |
0.110
|
|
|
|
regulation of endodermal cell fate specification
|
GO:0042663 |
1 |
0.109
|
Zebrafish |
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.107
|
|
|
|
nephron epithelium development
|
GO:0072009 |
23 |
0.106
|
|
|
|
nerve development
|
GO:0021675 |
4 |
0.105
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.105
|
Mouse Rat |
|
|
negative regulation of endodermal cell differentiation
|
GO:1903225 |
2 |
0.105
|
Zebrafish |
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
147 |
0.104
|
Human |
|
|
stem cell maintenance
|
GO:0019827 |
19 |
0.104
|
Mouse |
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.103
|
Rat |
|
|
hair cycle
|
GO:0042633 |
28 |
0.103
|
|
|
|
blood vessel development
|
GO:0001568 |
172 |
0.103
|
|
|
|
cell cell signaling
|
GO:0007267 |
155 |
0.102
|
Human Fly |
|
|
regulation of actin filament based process
|
GO:0032970 |
141 |
0.102
|
Human |
|
|
negative regulation of cell growth
|
GO:0030308 |
83 |
0.102
|
Human |
|
|
regulation of cell growth
|
GO:0001558 |
135 |
0.102
|
Human |
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.101
|
|
|
|
embryonic organ morphogenesis
|
GO:0048562 |
24 |
0.101
|
Zebrafish Mouse |
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.100
|
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.099
|
Fly |
|
|
segmentation
|
GO:0035282 |
4 |
0.099
|
|
|
|
cell morphogenesis involved in neuron differentiation
|
GO:0048667 |
44 |
0.096
|
Mouse |
|
|
negative regulation of cell motility
|
GO:2000146 |
104 |
0.096
|
Human |
|
|
renal tubule development
|
GO:0061326 |
19 |
0.095
|
|
|
|
regulation of cartilage development
|
GO:0061035 |
12 |
0.095
|
|
|
|
catagen
|
GO:0042637 |
3 |
0.094
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.093
|
Human |
|
|
sensory organ morphogenesis
|
GO:0090596 |
21 |
0.092
|
Mouse |
|
|
positive regulation of osteoblast differentiation
|
GO:0045669 |
23 |
0.091
|
|
|
|
skin development
|
GO:0043588 |
76 |
0.091
|
|
|
|
inorganic ion transmembrane transport
|
GO:0098660 |
231 |
0.091
|
|
|
|
embryonic organ development
|
GO:0048568 |
36 |
0.090
|
Zebrafish Mouse |
|
|
embryo development
|
GO:0009790 |
123 |
0.090
|
Human Zebrafish Mouse |
|
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
0.090
|
Human |
|
|
nephron epithelium morphogenesis
|
GO:0072088 |
15 |
0.090
|
|
|
|
biological adhesion
|
GO:0022610 |
331 |
0.090
|
|
|
|
dorsal ventral pattern formation
|
GO:0009953 |
15 |
0.089
|
Zebrafish Fly |
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
175 |
0.089
|
|
|
|
negative regulation of glial cell differentiation
|
GO:0045686 |
1 |
0.089
|
|
|
|
regulation of cardiac muscle cell proliferation
|
GO:0060043 |
4 |
0.088
|
|
|
|
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090101 |
45 |
0.088
|
|
|
|
chordate embryonic development
|
GO:0043009 |
34 |
0.088
|
Mouse |
|
|
tissue migration
|
GO:0090130 |
119 |
0.088
|
Human |
|
|
epithelium migration
|
GO:0090132 |
119 |
0.086
|
Human |
|
|
blood vessel morphogenesis
|
GO:0048514 |
162 |
0.086
|
Human |
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.085
|
|
|
|
embryonic appendage morphogenesis
|
GO:0035113 |
9 |
0.085
|
Mouse |
|
|
regulation of neurogenesis
|
GO:0050767 |
82 |
0.083
|
|
|
|
reproductive process
|
GO:0022414 |
106 |
0.083
|
Human Mouse Fly |
|
|
positive regulation of mesonephros development
|
GO:0061213 |
2 |
0.083
|
|
|
|
nephron tubule morphogenesis
|
GO:0072078 |
13 |
0.083
|
|
|
|
renal system development
|
GO:0072001 |
63 |
0.082
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.082
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.082
|
Human Rat |
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.081
|
Human Mouse |
|
|
regulation of male gonad development
|
GO:2000018 |
4 |
0.081
|
|
|
|
wound healing
|
GO:0042060 |
115 |
0.081
|
|
|
|
mesonephric tubule morphogenesis
|
GO:0072171 |
10 |
0.081
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.081
|
Human |
|
|
negative regulation of cellular component movement
|
GO:0051271 |
106 |
0.080
|
Human |
|
|
regulation of cell projection organization
|
GO:0031344 |
107 |
0.080
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.080
|
|
|
|
neural tube development
|
GO:0021915 |
9 |
0.079
|
|
|
|
muscle cell proliferation
|
GO:0033002 |
35 |
0.079
|
|
|
|
cartilage condensation
|
GO:0001502 |
1 |
0.078
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
135 |
0.078
|
Human |
|
|
tube closure
|
GO:0060606 |
3 |
0.077
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
26 |
0.076
|
|
|
|
forebrain generation of neurons
|
GO:0021872 |
3 |
0.075
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
269 |
0.075
|
|
|
|
ureteric bud morphogenesis
|
GO:0060675 |
10 |
0.074
|
|
|
|
bmp signaling pathway involved in heart development
|
GO:0061312 |
3 |
0.074
|
Zebrafish |
|
|
embryonic digit morphogenesis
|
GO:0042733 |
6 |
0.073
|
|
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.073
|
Human Rat |
|
|
regulation of cell morphogenesis involved in differentiation
|
GO:0010769 |
83 |
0.073
|
|
|
|
regulation of muscle organ development
|
GO:0048634 |
27 |
0.073
|
Fly |
|
|
negative regulation of locomotion
|
GO:0040013 |
118 |
0.073
|
Human |
|
|
cation transmembrane transport
|
GO:0098655 |
238 |
0.071
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
180 |
0.071
|
Human |
|
|
response to lipid
|
GO:0033993 |
206 |
0.071
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.070
|
|
|
|
regulation of endodermal cell differentiation
|
GO:1903224 |
3 |
0.070
|
Zebrafish |
|
|
mesenchymal cell differentiation
|
GO:0048762 |
52 |
0.069
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
195 |
0.069
|
Human Rat |
|
|
inner ear morphogenesis
|
GO:0042472 |
4 |
0.069
|
|
|
|
inorganic cation transmembrane transport
|
GO:0098662 |
194 |
0.069
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.069
|
|
|
|
circulatory system process
|
GO:0003013 |
113 |
0.068
|
Human |
|
|
regulation of endopeptidase activity
|
GO:0052548 |
170 |
0.068
|
Human |
|
|
regulation of cardiac muscle tissue development
|
GO:0055024 |
13 |
0.068
|
|
|
|
nephron morphogenesis
|
GO:0072028 |
15 |
0.067
|
Mouse |
|
|
glomerulus development
|
GO:0032835 |
15 |
0.067
|
|
|
|
negative regulation of astrocyte differentiation
|
GO:0048712 |
1 |
0.067
|
|
|
|
peripheral nervous system development
|
GO:0007422 |
2 |
0.067
|
|
|
|
axonogenesis
|
GO:0007409 |
31 |
0.067
|
Mouse |
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.066
|
Human Mouse |
|
|
cranial nerve development
|
GO:0021545 |
4 |
0.066
|
|
|
|
neural crest cell development
|
GO:0014032 |
3 |
0.066
|
|
|
|
oogenesis
|
GO:0048477 |
2 |
0.066
|
Fly |
|
|
negative regulation of bmp signaling pathway
|
GO:0030514 |
17 |
0.066
|
|
|
|
positive regulation of ossification
|
GO:0045778 |
32 |
0.065
|
|
|
|
cardiac muscle cell contraction
|
GO:0086003 |
4 |
0.065
|
|
|
|
negative regulation of transport
|
GO:0051051 |
176 |
0.065
|
Human Rat |
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.064
|
|
|
|
transmembrane transport
|
GO:0055085 |
399 |
0.064
|
|
|
|
neural tube closure
|
GO:0001843 |
3 |
0.064
|
|
|
|
locomotory behavior
|
GO:0007626 |
1 |
0.063
|
|
|
|
axon development
|
GO:0061564 |
34 |
0.062
|
Mouse |
|
|
positive regulation of cell motility
|
GO:2000147 |
177 |
0.062
|
|
|
|
regulation of protein localization to nucleus
|
GO:1900180 |
85 |
0.062
|
Human Rat |
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.062
|
|
|
|
cell growth
|
GO:0016049 |
160 |
0.061
|
Human |
|
|
sensory organ development
|
GO:0007423 |
52 |
0.060
|
Mouse |
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.060
|
Human Rat |
|
|
limb bud formation
|
GO:0060174 |
1 |
0.060
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
176 |
0.060
|
Human Rat |
|
|
positive regulation of cell development
|
GO:0010720 |
92 |
0.059
|
|
|
|
immune response
|
GO:0006955 |
307 |
0.059
|
Human |
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
149 |
0.059
|
Human Rat |
|
|
membrane organization
|
GO:0061024 |
292 |
0.059
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
391 |
0.059
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
181 |
0.059
|
Human |
|
|
negative regulation of cardiac muscle cell proliferation
|
GO:0060044 |
2 |
0.058
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.058
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
125 |
0.058
|
Mouse Rat |
|
|
regulation of neuron differentiation
|
GO:0045664 |
70 |
0.058
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
211 |
0.057
|
Human Rat |
|
|
kidney development
|
GO:0001822 |
53 |
0.057
|
|
|
|
positive regulation of gtpase activity
|
GO:0043547 |
166 |
0.057
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
405 |
0.056
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.056
|
|
|
|
regulation of cellular response to growth factor stimulus
|
GO:0090287 |
76 |
0.056
|
|
|
|
appendage development
|
GO:0048736 |
23 |
0.056
|
Mouse Fly |
|
|
endocrine system development
|
GO:0035270 |
26 |
0.056
|
Human |
|
|
positive regulation of locomotion
|
GO:0040017 |
186 |
0.055
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.055
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.055
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
264 |
0.055
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.055
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.055
|
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
180 |
0.054
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
244 |
0.054
|
|
|
|
positive regulation of branching involved in ureteric bud morphogenesis
|
GO:0090190 |
2 |
0.054
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
140 |
0.054
|
|
|
|
gtp metabolic process
|
GO:0046039 |
239 |
0.054
|
|
|
|
lipid biosynthetic process
|
GO:0008610 |
177 |
0.054
|
Human |
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.054
|
|
|
|
cellular response to lipid
|
GO:0071396 |
127 |
0.054
|
|
|
|
regulation of bmp signaling pathway
|
GO:0030510 |
27 |
0.053
|
|
|
|
cell aggregation
|
GO:0098743 |
1 |
0.053
|
|
|
|
positive regulation of canonical wnt signaling pathway
|
GO:0090263 |
33 |
0.053
|
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
97 |
0.053
|
|
|
|
regulation of neuron projection development
|
GO:0010975 |
57 |
0.053
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
227 |
0.052
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.052
|
|
|
|
striated muscle tissue development
|
GO:0014706 |
59 |
0.052
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
189 |
0.051
|
|
|
|
muscle tissue development
|
GO:0060537 |
62 |
0.051
|
|
|
|
small molecule biosynthetic process
|
GO:0044283 |
157 |
0.051
|
Human |
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.051
|
Human Rat |
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.051
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.051
|
Human |
|
|
action potential
|
GO:0001508 |
34 |
0.051
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.050
|
Human Mouse |
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.050
|
|
|
|
positive regulation of aldosterone metabolic process
|
GO:0032346 |
2 |
0.050
|
Human |
|
|
positive regulation of cell migration
|
GO:0030335 |
172 |
0.049
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.049
|
|
|
|
ear morphogenesis
|
GO:0042471 |
7 |
0.049
|
|
|
|
ion transmembrane transport
|
GO:0034220 |
338 |
0.049
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.049
|
|
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.049
|
Human |
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.048
|
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
142 |
0.048
|
Human |
|
|
renal tubule morphogenesis
|
GO:0061333 |
14 |
0.048
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
193 |
0.048
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.048
|
|
|
|
glial cell migration
|
GO:0008347 |
4 |
0.048
|
|
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
127 |
0.047
|
|
|
|
positive regulation of aldosterone biosynthetic process
|
GO:0032349 |
2 |
0.047
|
Human |
|
|
cell fate specification
|
GO:0001708 |
8 |
0.047
|
Zebrafish |
|
|
heart formation
|
GO:0060914 |
2 |
0.047
|
|
|
|
regulation of kidney development
|
GO:0090183 |
10 |
0.046
|
|
|
|
single organism reproductive process
|
GO:0044702 |
98 |
0.046
|
Human Mouse Fly |
|
|
ear development
|
GO:0043583 |
14 |
0.046
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
408 |
0.046
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
230 |
0.046
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
172 |
0.046
|
Human Rat |
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.046
|
|
|
|
gliogenesis
|
GO:0042063 |
21 |
0.045
|
|
|
|
neurological system process
|
GO:0050877 |
163 |
0.045
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
204 |
0.045
|
|
|
|
epidermal cell differentiation
|
GO:0009913 |
45 |
0.045
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.045
|
|
|
|
anterior posterior axis specification
|
GO:0009948 |
2 |
0.045
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.045
|
|
|
|
muscle system process
|
GO:0003012 |
81 |
0.044
|
Human |
|
|
forelimb morphogenesis
|
GO:0035136 |
4 |
0.044
|
|
|
|
neuroblast proliferation
|
GO:0007405 |
4 |
0.044
|
|
|
|
nephron tubule development
|
GO:0072080 |
17 |
0.044
|
|
|
|
regulation of nucleocytoplasmic transport
|
GO:0046822 |
98 |
0.044
|
Human Rat |
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.043
|
Rat |
|
|
retinal ganglion cell axon guidance
|
GO:0031290 |
2 |
0.043
|
|
|
|
regulation of neurotransmitter secretion
|
GO:0046928 |
3 |
0.043
|
Fly |
|
|
protein import into nucleus
|
GO:0006606 |
104 |
0.042
|
Human Rat |
|
|
mapk cascade
|
GO:0000165 |
288 |
0.042
|
|
|
|
response to fibroblast growth factor
|
GO:0071774 |
39 |
0.042
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.042
|
|
|
|
branching involved in ureteric bud morphogenesis
|
GO:0001658 |
9 |
0.042
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.042
|
|
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
200 |
0.041
|
|
|
|
protein import
|
GO:0017038 |
130 |
0.041
|
Human Rat |
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
398 |
0.041
|
|
|
|
regulation of cell morphogenesis
|
GO:0022604 |
153 |
0.041
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.041
|
|
|
|
protein targeting
|
GO:0006605 |
187 |
0.041
|
Human Rat |
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.041
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
412 |
0.040
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.040
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.040
|
|
|
|
tongue development
|
GO:0043586 |
1 |
0.040
|
|
|
|
cellular response to nitrogen compound
|
GO:1901699 |
144 |
0.040
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
95 |
0.040
|
|
|
|
embryonic limb morphogenesis
|
GO:0030326 |
9 |
0.040
|
Mouse |
|
|
leukocyte activation
|
GO:0045321 |
164 |
0.039
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
411 |
0.039
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
239 |
0.039
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.039
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
408 |
0.039
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
177 |
0.039
|
Human |
|
|
regulation of gtpase activity
|
GO:0043087 |
180 |
0.039
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.039
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
166 |
0.038
|
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
123 |
0.038
|
Human Rat |
|
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.038
|
|
|
|
cell differentiation in spinal cord
|
GO:0021515 |
1 |
0.038
|
|
|
|
epithelial cell migration
|
GO:0010631 |
119 |
0.038
|
Human |
|
|
ion homeostasis
|
GO:0050801 |
230 |
0.038
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
405 |
0.038
|
|
|
|
metal ion transport
|
GO:0030001 |
272 |
0.037
|
|
|
|
positive regulation of cytoplasmic transport
|
GO:1903651 |
82 |
0.037
|
Human |
|
|
developmental process involved in reproduction
|
GO:0003006 |
66 |
0.037
|
Human Mouse Fly |
|
|
chemical homeostasis
|
GO:0048878 |
306 |
0.037
|
|
|
|
negative regulation of binding
|
GO:0051100 |
57 |
0.037
|
|
|
|
organic hydroxy compound biosynthetic process
|
GO:1901617 |
71 |
0.036
|
Human |
|
|
endochondral bone morphogenesis
|
GO:0060350 |
3 |
0.036
|
|
|
|
nuclear import
|
GO:0051170 |
106 |
0.036
|
Human Rat |
|
|
middle ear morphogenesis
|
GO:0042474 |
1 |
0.036
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
205 |
0.036
|
|
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
207 |
0.036
|
|
|
|
regulation of binding
|
GO:0051098 |
111 |
0.036
|
|
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.036
|
Human Rat |
|
|
behavior
|
GO:0007610 |
112 |
0.036
|
|
|
|
axon guidance
|
GO:0007411 |
12 |
0.036
|
Mouse |
|
|
cellular homeostasis
|
GO:0019725 |
196 |
0.036
|
|
|
|
angiogenesis
|
GO:0001525 |
147 |
0.036
|
Human |
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
213 |
0.035
|
|
|
|
actin mediated cell contraction
|
GO:0070252 |
12 |
0.035
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
404 |
0.035
|
|
|
|
fibroblast growth factor receptor signaling pathway
|
GO:0008543 |
26 |
0.035
|
|
|
|
negative regulation of nervous system development
|
GO:0051961 |
28 |
0.035
|
|
|
|
nuclear transport
|
GO:0051169 |
179 |
0.035
|
Human Rat |
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
207 |
0.035
|
|
|
|
protein localization to plasma membrane
|
GO:0072659 |
93 |
0.035
|
|
|
|
positive regulation of odontogenesis
|
GO:0042482 |
3 |
0.035
|
|
|
|
pattern specification process
|
GO:0007389 |
43 |
0.035
|
Human Zebrafish Mouse Fly |
|
|
cation homeostasis
|
GO:0055080 |
189 |
0.035
|
|
|
|
regulation of striated muscle tissue development
|
GO:0016202 |
26 |
0.034
|
|
|
|
cation transport
|
GO:0006812 |
331 |
0.034
|
|
|
|
positive regulation of neurogenesis
|
GO:0050769 |
49 |
0.034
|
|
|
|
regulation of small gtpase mediated signal transduction
|
GO:0051056 |
156 |
0.034
|
|
|
|
positive regulation of wnt signaling pathway
|
GO:0030177 |
54 |
0.034
|
|
|
|
muscle contraction
|
GO:0006936 |
73 |
0.034
|
Human |
|
|
cell cycle phase transition
|
GO:0044770 |
173 |
0.034
|
|
|
|
specification of organ identity
|
GO:0010092 |
3 |
0.034
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.034
|
|
|
|
blastoderm segmentation
|
GO:0007350 |
2 |
0.034
|
|
|
|
regulation of gliogenesis
|
GO:0014013 |
7 |
0.034
|
|
|
|
protein targeting to nucleus
|
GO:0044744 |
104 |
0.034
|
Human Rat |
|
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
185 |
0.034
|
|
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.034
|
|
|
|
regulation of protein stability
|
GO:0031647 |
87 |
0.034
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
136 |
0.033
|
|
|
|
regulation of hormone levels
|
GO:0010817 |
125 |
0.033
|
Human |
|
|
plasma membrane organization
|
GO:0007009 |
115 |
0.033
|
|
|
|
epidermis development
|
GO:0008544 |
59 |
0.033
|
|
|
|
alcohol metabolic process
|
GO:0006066 |
114 |
0.033
|
Human |
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.033
|
Human Rat |
|
|
forebrain neuron differentiation
|
GO:0021879 |
3 |
0.033
|
|
|
|
positive regulation of ras gtpase activity
|
GO:0032320 |
117 |
0.033
|
|
|
|
developmental growth
|
GO:0048589 |
48 |
0.033
|
Fly |
|
|
regulation of protein binding
|
GO:0043393 |
66 |
0.033
|
|
|
|
positive regulation of peptidase activity
|
GO:0010952 |
88 |
0.033
|
Human |
|
|
lung alveolus development
|
GO:0048286 |
4 |
0.033
|
|
|
|
mesenchymal to epithelial transition involved in metanephros morphogenesis
|
GO:0003337 |
4 |
0.033
|
|
|
|
endomembrane system organization
|
GO:0010256 |
196 |
0.033
|
|
|
|
hormone metabolic process
|
GO:0042445 |
61 |
0.033
|
Human |
|
|
negative regulation of axonogenesis
|
GO:0050771 |
4 |
0.033
|
|
|
|
morphogenesis of a polarized epithelium
|
GO:0001738 |
3 |
0.032
|
|
|
|
regulation of cell fate commitment
|
GO:0010453 |
7 |
0.032
|
Zebrafish |
|
|
establishment of protein localization to membrane
|
GO:0090150 |
121 |
0.032
|
|
|
|
regulation of ras gtpase activity
|
GO:0032318 |
128 |
0.032
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
392 |
0.032
|
|
|
|
positive regulation of nervous system development
|
GO:0051962 |
54 |
0.032
|
|
|
|
mitotic cell cycle phase transition
|
GO:0044772 |
162 |
0.032
|
|
|
|
reproductive structure development
|
GO:0048608 |
55 |
0.032
|
Human Mouse Fly |
|
|
respiratory system development
|
GO:0060541 |
22 |
0.032
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
169 |
0.032
|
|
|
|
positive regulation of cellular component movement
|
GO:0051272 |
181 |
0.032
|
|
|
|
protein processing
|
GO:0016485 |
226 |
0.032
|
|
|
|
positive regulation of insulin like growth factor receptor signaling pathway
|
GO:0043568 |
4 |
0.032
|
|
|
|
positive regulation of neural precursor cell proliferation
|
GO:2000179 |
2 |
0.031
|
|
|
|
sex determination
|
GO:0007530 |
3 |
0.031
|
|
|
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
116 |
0.031
|
Human |
|
|
regeneration
|
GO:0031099 |
4 |
0.031
|
|
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.031
|
|
|
|
cellular response to bmp stimulus
|
GO:0071773 |
8 |
0.031
|
Human |
