Homo sapiens

100 known processes

E2F8

E2F transcription factor 8

(Aliases: FLJ23311,E2F-8)

E2F8 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
hepatocyte differentiation GO:0070365 1 0.986
Mouse
sprouting angiogenesis GO:0002040 29 0.942
negative regulation of cytokinesis GO:0032466 3 0.900
Mouse
dna dependent dna replication GO:0006261 44 0.749
Mouse
dna replication GO:0006260 116 0.745
Mouse
positive regulation of dna metabolic process GO:0051054 73 0.743
Mouse
regulation of transcription involved in g1 s transition of mitotic cell cycle GO:0000083 8 0.738
Human
dna damage response signal transduction by p53 class mediator GO:0030330 44 0.689
Human
positive regulation of dna replication GO:0045740 35 0.622
Mouse
vasculature development GO:0001944 181 0.579
cardiovascular system development GO:0072358 262 0.564
positive regulation of cell cycle GO:0045787 140 0.542
Mouse
negative regulation of cell proliferation GO:0008285 228 0.535
Human
signal transduction in response to dna damage GO:0042770 57 0.511
Human
blood vessel development GO:0001568 172 0.450
blood vessel morphogenesis GO:0048514 162 0.433
positive regulation of cell cycle process GO:0090068 106 0.428
Mouse
regulation of cytokinesis GO:0032465 45 0.421
Mouse
anatomical structure formation involved in morphogenesis GO:0048646 284 0.419
regulation of dna endoreduplication GO:0032875 5 0.419
Mouse
angiogenesis GO:0001525 147 0.398
g1 s transition of mitotic cell cycle GO:0000082 78 0.389
Human
cytokinesis GO:0000910 96 0.317
Mouse
cell cycle g1 s phase transition GO:0044843 80 0.307
Human
regulation of cell cycle GO:0051726 393 0.301
Mouse
negative regulation of cell cycle process GO:0010948 121 0.295
Mouse
negative regulation of cell cycle GO:0045786 193 0.292
Mouse
regulation of dna replication GO:0006275 68 0.287
Mouse
negative regulation of mitotic cell cycle phase transition GO:1901991 85 0.286
mitotic cell cycle phase transition GO:0044772 162 0.278
Human
cell cycle phase transition GO:0044770 173 0.255
Human
gland development GO:0048732 48 0.253
Mouse
regulation of cell division GO:0051302 116 0.243
Mouse
epithelium development GO:0060429 227 0.242
Mouse
negative regulation of cell cycle g1 s phase transition GO:1902807 29 0.240
negative regulation of g1 s transition of mitotic cell cycle GO:2000134 29 0.235
mitotic cell cycle GO:0000278 326 0.218
Human Mouse
mitotic cell cycle process GO:1903047 286 0.203
Human
post embryonic development GO:0009791 2 0.203
regulation of dna dependent dna replication GO:0090329 19 0.203
Mouse
negative regulation of cell division GO:0051782 31 0.185
Mouse
regulation of mitotic cell cycle GO:0007346 189 0.179
hepaticobiliary system development GO:0061008 10 0.178
Mouse
chordate embryonic development GO:0043009 34 0.171
Mouse
regulation of g1 s transition of mitotic cell cycle GO:2000045 40 0.170
placenta development GO:0001890 10 0.167
Mouse
negative regulation of cell cycle phase transition GO:1901988 89 0.166
negative regulation of mitotic cell cycle GO:0045930 102 0.158
embryonic organ development GO:0048568 36 0.150
Mouse
regulation of cell cycle phase transition GO:1901987 126 0.128
regulation of mitotic cell cycle phase transition GO:1901990 118 0.114
regulation of cell differentiation GO:0045595 393 0.080
cellular amino acid metabolic process GO:0006520 116 0.076
amine metabolic process GO:0009308 44 0.071
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.067
chromatin organization GO:0006325 351 0.066
reproductive process GO:0022414 106 0.062
Mouse
cellular response to dna damage stimulus GO:0006974 379 0.061
Human
cell cycle dna replication GO:0044786 11 0.059
Mouse
regulation of cellular amine metabolic process GO:0033238 11 0.057
reproductive system development GO:0061458 56 0.057
Mouse
dna repair GO:0006281 198 0.056
cellular component morphogenesis GO:0032989 314 0.055
single organism reproductive process GO:0044702 98 0.055
Mouse
regulation of cellular amino acid metabolic process GO:0006521 6 0.054
purine containing compound catabolic process GO:0072523 411 0.054
cell development GO:0048468 328 0.052
response to abiotic stimulus GO:0009628 336 0.049
regulation of cell cycle process GO:0010564 266 0.047
Mouse
dna conformation change GO:0071103 113 0.047
cellular ketone metabolic process GO:0042180 80 0.044
regulation of cellular ketone metabolic process GO:0010565 50 0.042
cellular amine metabolic process GO:0044106 41 0.042
negative regulation of programmed cell death GO:0043069 321 0.042
immune system development GO:0002520 195 0.041
oogenesis GO:0048477 2 0.041
reproductive structure development GO:0048608 55 0.041
Mouse
hematopoietic or lymphoid organ development GO:0048534 186 0.041
nucleoside phosphate catabolic process GO:1901292 412 0.040
purine ribonucleoside metabolic process GO:0046128 437 0.040
embryo development ending in birth or egg hatching GO:0009792 34 0.040
Mouse
nucleoside triphosphate metabolic process GO:0009141 422 0.039
hemopoiesis GO:0030097 180 0.039
wnt signaling pathway GO:0016055 156 0.038
immune response GO:0006955 307 0.038
cell projection organization GO:0030030 252 0.037
purine nucleotide catabolic process GO:0006195 405 0.036
female gamete generation GO:0007292 2 0.036
positive regulation of cell differentiation GO:0045597 211 0.035
ribonucleotide catabolic process GO:0009261 405 0.035
nervous system development GO:0007399 293 0.035
negative regulation of phosphate metabolic process GO:0045936 267 0.035
positive regulation of apoptotic process GO:0043065 246 0.035
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.034
negative regulation of protein metabolic process GO:0051248 391 0.033
multicellular organismal aging GO:0010259 3 0.033
regulation of dna metabolic process GO:0051052 153 0.032
Mouse
cytoplasmic transport GO:0016482 379 0.032
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.032
regulation of proteolysis GO:0030162 293 0.031
positive regulation of cellular amine metabolic process GO:0033240 7 0.031
positive regulation of hydrolase activity GO:0051345 331 0.030
regulation of protein localization GO:0032880 296 0.030
positive regulation of catabolic process GO:0009896 310 0.030
positive regulation of programmed cell death GO:0043068 249 0.030
positive regulation of cellular component organization GO:0051130 376 0.030
purine nucleoside catabolic process GO:0006152 398 0.029
neurogenesis GO:0022008 169 0.029
regulation of protein transport GO:0051223 213 0.028
vesicle mediated transport GO:0016192 371 0.028
protein dna complex subunit organization GO:0071824 80 0.028
locomotory behavior GO:0007626 1 0.027
intracellular protein transport GO:0006886 270 0.027
determination of adult lifespan GO:0008340 2 0.027
single organism cellular localization GO:1902580 332 0.027
purine ribonucleoside catabolic process GO:0046130 398 0.027
cellular lipid metabolic process GO:0044255 303 0.027
regulation of establishment of protein localization GO:0070201 242 0.027
purine nucleoside triphosphate metabolic process GO:0009144 412 0.027
negative regulation of cellular protein metabolic process GO:0032269 353 0.026
protein localization to organelle GO:0033365 280 0.026
transmembrane transport GO:0055085 399 0.026
glycosyl compound catabolic process GO:1901658 413 0.026
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.026
embryo development GO:0009790 123 0.025
Mouse
negative regulation of apoptotic process GO:0043066 316 0.025
ribonucleoside triphosphate catabolic process GO:0009203 391 0.025
membrane organization GO:0061024 292 0.025
dna endoreduplication GO:0042023 5 0.025
Mouse
apoptotic signaling pathway GO:0097190 268 0.025
ras protein signal transduction GO:0007265 73 0.024
regulation of kinase activity GO:0043549 314 0.024
single organism membrane organization GO:0044802 268 0.024
negative regulation of multicellular organismal process GO:0051241 317 0.024
myeloid cell differentiation GO:0030099 117 0.024
positive regulation of cellular catabolic process GO:0031331 284 0.023
gtp metabolic process GO:0046039 239 0.023
generation of neurons GO:0048699 152 0.023
maintenance of location GO:0051235 112 0.023
positive regulation of protein phosphorylation GO:0001934 313 0.022
regulation of cell morphogenesis GO:0022604 153 0.022
covalent chromatin modification GO:0016569 254 0.022
cellular macromolecule catabolic process GO:0044265 380 0.022
protein catabolic process GO:0030163 325 0.022
positive regulation of cell death GO:0010942 263 0.022
regulation of peptidase activity GO:0052547 180 0.022
cell fate determination GO:0001709 3 0.022
defense response GO:0006952 315 0.021
response to oxygen containing compound GO:1901700 369 0.021
cellular macromolecular complex assembly GO:0034622 324 0.021
positive regulation of transport GO:0051050 336 0.021
signal transduction by phosphorylation GO:0023014 297 0.021
purine nucleoside triphosphate catabolic process GO:0009146 392 0.021
lipid metabolic process GO:0006629 381 0.021
small gtpase mediated signal transduction GO:0007264 78 0.021
negative regulation of cell death GO:0060548 345 0.021
regulation of cellular component biogenesis GO:0044087 281 0.020
cellular response to oxygen containing compound GO:1901701 276 0.020
negative regulation of cell differentiation GO:0045596 171 0.020
negative regulation of cellular component organization GO:0051129 235 0.020
chromatin assembly or disassembly GO:0006333 78 0.020
neuromuscular junction development GO:0007528 3 0.020
epithelial cell proliferation GO:0050673 128 0.020
regulation of nucleotide catabolic process GO:0030811 205 0.020
organophosphate catabolic process GO:0046434 430 0.020
chemical homeostasis GO:0048878 306 0.020
protein targeting GO:0006605 187 0.020
regeneration GO:0031099 4 0.020
endomembrane system organization GO:0010256 196 0.020
growth GO:0040007 202 0.019
positive regulation of immune system process GO:0002684 283 0.019
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.019
mapk cascade GO:0000165 288 0.019
regulation of cellular response to stress GO:0080135 244 0.019
chromatin modification GO:0016568 298 0.019
cell morphogenesis GO:0000902 296 0.019
regulation of nucleoside metabolic process GO:0009118 209 0.019
negative regulation of protein modification process GO:0031400 200 0.019
protein dna complex assembly GO:0065004 64 0.019
regulation of transferase activity GO:0051338 355 0.019
regulation of nucleotide metabolic process GO:0006140 269 0.019
negative regulation of intracellular signal transduction GO:1902532 183 0.019
negative regulation of hydrolase activity GO:0051346 182 0.019
regulation of cell motility GO:2000145 299 0.018
negative regulation of catalytic activity GO:0043086 335 0.018
organ morphogenesis GO:0009887 147 0.018
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.018
positive regulation of cell proliferation GO:0008284 301 0.018
enzyme linked receptor protein signaling pathway GO:0007167 303 0.018
oocyte development GO:0048599 1 0.018
ribonucleoside catabolic process GO:0042454 406 0.018
actin filament based process GO:0030029 224 0.018
circulatory system development GO:0072359 262 0.018
histone modification GO:0016570 251 0.017
carbohydrate metabolic process GO:0005975 207 0.017
regulation of cellular component movement GO:0051270 334 0.017
purine nucleoside monophosphate metabolic process GO:0009126 186 0.017
peripheral nervous system development GO:0007422 2 0.017
guanosine containing compound metabolic process GO:1901068 244 0.017
purine nucleoside monophosphate catabolic process GO:0009128 158 0.017
biological adhesion GO:0022610 331 0.017
nuclear transport GO:0051169 179 0.017
cell division GO:0051301 168 0.017
Mouse
regulation of purine nucleotide metabolic process GO:1900542 264 0.017
protein ubiquitination GO:0016567 314 0.017
nitrogen compound transport GO:0071705 191 0.017
ion transmembrane transport GO:0034220 338 0.016
regulation of intracellular transport GO:0032386 195 0.016
regulation of gtpase activity GO:0043087 180 0.016
positive regulation of organelle organization GO:0010638 195 0.016
positive regulation of nucleotide metabolic process GO:0045981 230 0.016
rna processing GO:0006396 255 0.016
response to lipid GO:0033993 206 0.016
nucleotide catabolic process GO:0009166 408 0.016
cell growth GO:0016049 160 0.016
oxidation reduction process GO:0055114 396 0.016
regulation of cytoplasmic transport GO:1903649 149 0.016
regulation of purine nucleotide catabolic process GO:0033121 205 0.016
regulation of binding GO:0051098 111 0.016
response to oxidative stress GO:0006979 121 0.016
endocytosis GO:0006897 159 0.016
organelle assembly GO:0070925 176 0.016
organonitrogen compound biosynthetic process GO:1901566 200 0.016
ion homeostasis GO:0050801 230 0.016
system process GO:0003008 349 0.016
neuron differentiation GO:0030182 138 0.015
cell part morphogenesis GO:0032990 137 0.015
regulation of protein complex assembly GO:0043254 147 0.015
innate immune response GO:0045087 178 0.015
regulation of cell migration GO:0030334 289 0.015
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.015
negative regulation of phosphorus metabolic process GO:0010563 267 0.015
purine ribonucleotide catabolic process GO:0009154 404 0.015
guanosine containing compound catabolic process GO:1901069 239 0.015
gtp catabolic process GO:0006184 237 0.015
brain development GO:0007420 97 0.015
positive regulation of phosphorylation GO:0042327 394 0.015
carbohydrate derivative biosynthetic process GO:1901137 207 0.015
metal ion transport GO:0030001 272 0.015
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.015
secretion GO:0046903 254 0.015
segmentation GO:0035282 4 0.015
nucleoside catabolic process GO:0009164 408 0.015
regulation of wnt signaling pathway GO:0030111 123 0.015
regulation of epithelial cell proliferation GO:0050678 113 0.015
regulation of multi organism process GO:0043900 157 0.015
rho protein signal transduction GO:0007266 26 0.015
regulation of apoptotic signaling pathway GO:2001233 175 0.015
positive regulation of protein kinase activity GO:0045860 190 0.015
spermatid differentiation GO:0048515 4 0.015
secretion by cell GO:0032940 226 0.015
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 69 0.015
response to light stimulus GO:0009416 87 0.014
cellular response to growth factor stimulus GO:0071363 197 0.014
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.014
response to external biotic stimulus GO:0043207 261 0.014
cellular response to endogenous stimulus GO:0071495 336 0.014
dna recombination GO:0006310 77 0.014
protein oligomerization GO:0051259 173 0.014
hindbrain development GO:0030902 3 0.014
protein homooligomerization GO:0051260 100 0.014
neuron development GO:0048666 113 0.014
cellular response to oxidative stress GO:0034599 85 0.014
intrinsic apoptotic signaling pathway GO:0097193 127 0.014
regulation of cell growth GO:0001558 135 0.014
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.014
nucleocytoplasmic transport GO:0006913 176 0.014
regulation of response to external stimulus GO:0032101 222 0.014
regulation of immune response GO:0050776 201 0.014
regulation of protein kinase activity GO:0045859 289 0.014
positive regulation of protein transport GO:0051222 135 0.014
spermatid development GO:0007286 4 0.014
interspecies interaction between organisms GO:0044419 156 0.014
oocyte differentiation GO:0009994 2 0.013
single organism carbohydrate metabolic process GO:0044723 193 0.013
positive regulation of nucleotide catabolic process GO:0030813 185 0.013
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.013
positive regulation of gtpase activity GO:0043547 166 0.013
nucleoside triphosphate catabolic process GO:0009143 394 0.013
protein modification by small protein conjugation GO:0032446 342 0.013
protein import GO:0017038 130 0.013
epithelial cell differentiation GO:0030855 141 0.013
Mouse
establishment of protein localization to organelle GO:0072594 172 0.013
regulation of protein serine threonine kinase activity GO:0071900 179 0.013
negative regulation of phosphorylation GO:0042326 174 0.013
regulation of gene expression epigenetic GO:0040029 73 0.013
immune effector process GO:0002252 159 0.013
actin cytoskeleton organization GO:0030036 207 0.013
response to other organism GO:0051707 261 0.013
chemotaxis GO:0006935 157 0.013
adult locomotory behavior GO:0008344 1 0.013
posttranscriptional regulation of gene expression GO:0010608 213 0.013
protein maturation GO:0051604 233 0.013
regulation of chromosome organization GO:0033044 103 0.013
regulation of secretion by cell GO:1903530 177 0.013
cellular protein catabolic process GO:0044257 261 0.013
regulation of neural precursor cell proliferation GO:2000177 4 0.013
regulation of secretion GO:0051046 194 0.013
peptidyl tyrosine modification GO:0018212 170 0.013
protein processing GO:0016485 226 0.013
ribonucleoside triphosphate metabolic process GO:0009199 412 0.013
monocarboxylic acid metabolic process GO:0032787 185 0.013
head development GO:0060322 108 0.013
positive regulation of nucleoside metabolic process GO:0045979 186 0.012
cation transmembrane transport GO:0098655 238 0.012
chromatin assembly GO:0031497 61 0.012
neuron projection development GO:0031175 106 0.012
positive regulation of developmental process GO:0051094 314 0.012
cell activation GO:0001775 213 0.012
dephosphorylation GO:0016311 209 0.012
reactive oxygen species metabolic process GO:0072593 75 0.012
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.012
negative regulation of transport GO:0051051 176 0.012
protein localization to nucleus GO:0034504 136 0.012
blastocyst development GO:0001824 3 0.012
response to wounding GO:0009611 168 0.012
response to biotic stimulus GO:0009607 276 0.012
cellular protein complex assembly GO:0043623 188 0.012
positive regulation of gtp catabolic process GO:0033126 166 0.012
negative regulation of transferase activity GO:0051348 124 0.012
regulation of cytoskeleton organization GO:0051493 177 0.012
regulation of mapk cascade GO:0043408 262 0.012
organophosphate biosynthetic process GO:0090407 163 0.012
negative regulation of protein phosphorylation GO:0001933 140 0.012
double strand break repair GO:0006302 101 0.012
positive regulation of proteolysis GO:0045862 142 0.012
morphogenesis of embryonic epithelium GO:0016331 4 0.012
cell projection assembly GO:0030031 126 0.012
ribonucleoside monophosphate metabolic process GO:0009161 187 0.011
regulation of gtp catabolic process GO:0033124 180 0.011
regulation of protein maturation GO:1903317 150 0.011
i kappab kinase nf kappab signaling GO:0007249 166 0.011
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.011
microtubule based process GO:0007017 210 0.011
cation transport GO:0006812 331 0.011
response to inorganic substance GO:0010035 127 0.011
positive regulation of locomotion GO:0040017 186 0.011
regulation of anatomical structure size GO:0090066 101 0.011
lymphocyte activation GO:0046649 133 0.011
negative regulation of cellular amine metabolic process GO:0033239 3 0.011
neurological system process GO:0050877 163 0.011
positive regulation of immune response GO:0050778 159 0.011
viral life cycle GO:0019058 132 0.011
cytokine production GO:0001816 247 0.011
response to hormone GO:0009725 175 0.011
response to organonitrogen compound GO:0010243 156 0.011
single organism cell adhesion GO:0098602 179 0.011
response to cytokine GO:0034097 232 0.011
regulation of intracellular protein transport GO:0033157 123 0.011
atp metabolic process GO:0046034 176 0.011
nerve development GO:0021675 4 0.011
heart development GO:0007507 95 0.011
positive regulation of cellular component biogenesis GO:0044089 158 0.011
response to bacterium GO:0009617 144 0.011
regulation of hormone levels GO:0010817 125 0.011
negative regulation of immune system process GO:0002683 136 0.011
embryonic epithelial tube formation GO:0001838 4 0.011
regulation of nucleocytoplasmic transport GO:0046822 98 0.011
cellular response to lipid GO:0071396 127 0.011
multi organism cellular process GO:0044764 156 0.011
ubiquitin dependent protein catabolic process GO:0006511 206 0.011
in utero embryonic development GO:0001701 8 0.011
Mouse
regulation of growth GO:0040008 165 0.011
divalent metal ion transport GO:0070838 152 0.011
response to growth factor GO:0070848 205 0.011
atp catabolic process GO:0006200 157 0.011
regulation of response to dna damage stimulus GO:2001020 94 0.011
cellular response to cytokine stimulus GO:0071345 181 0.010
positive regulation of transferase activity GO:0051347 227 0.010
regulation of defense response GO:0031347 154 0.010
regulation of protein processing GO:0070613 150 0.010
positive regulation of intracellular transport GO:0032388 104 0.010
regulation of anatomical structure morphogenesis GO:0022603 286 0.010
ameboidal type cell migration GO:0001667 135 0.010
translation GO:0006412 132 0.010
organelle fission GO:0048285 149 0.010
cellular component disassembly GO:0022411 92 0.010
regulation of phosphatase activity GO:0010921 81 0.010
inorganic ion transmembrane transport GO:0098660 231 0.010
nuclear import GO:0051170 106 0.010
cell adhesion GO:0007155 325 0.010
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 109 0.010
methylation GO:0032259 106 0.010
rna interference GO:0016246 4 0.010
cation homeostasis GO:0055080 189 0.010

E2F8 disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 295 0.016
inherited metabolic disorder DOID:655 242 0.016
central nervous system disease DOID:331 186 0.011
nervous system disease DOID:863 431 0.011
cancer DOID:162 167 0.010
disease of cellular proliferation DOID:14566 174 0.010
organ system cancer DOID:0050686 164 0.010