IMP

Process View

Homo sapiens

10 genes annotated in human

placenta development

The process whose specific outcome is the progression of the placenta over time, from its formation to the mature structure. The placenta is an organ of metabolic interchange between fetus and mother, partly of embryonic origin and partly of maternal origin.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "placenta development"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "placenta development" (in gray)

Name	Description	Probability	Func Analog Organism
SP1	Sp1 transcription factor	0.894	Mouse
NCOA1	nuclear receptor coactivator 1	0.692	Mouse
EP300	E1A binding protein p300	0.643
MAPK1	mitogen-activated protein kinase 1	0.409	Mouse
PPARGC1A	peroxisome proliferator-activated receptor gamma, coactivator 1 alpha	0.318
E2F7	E2F transcription factor 7	0.291	Mouse
ESR1	estrogen receptor 1	0.270	Rat
HNF4A	hepatocyte nuclear factor 4, alpha	0.248
CAV1	caveolin 1, caveolae protein, 22kDa	0.246
NCOR2	nuclear receptor corepressor 2	0.201
EPAS1	endothelial PAS domain protein 1	0.187	Mouse
EGR1	early growth response 1	0.182
MAPK14	mitogen-activated protein kinase 14	0.181
E2F8	E2F transcription factor 8	0.167	Mouse
NR4A1	nuclear receptor subfamily 4, group A, member 1	0.156
RARA	retinoic acid receptor, alpha	0.154
CREBBP	CREB binding protein	0.129
SMARCC1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1	0.118
PDGFRB	platelet-derived growth factor receptor, beta polypeptide	0.085
PDGFRA	platelet-derived growth factor receptor, alpha polypeptide	0.082
JUN	jun proto-oncogene	0.078
TP53	tumor protein p53	0.076
GABPA	GA binding protein transcription factor, alpha subunit 60kDa	0.074
ATF2	activating transcription factor 2	0.066
HIF1A	hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	0.062	Mouse
SMARCA4	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4	0.059
KRT15	keratin 15	0.053
DUSP1	dual specificity phosphatase 1	0.052
XRCC6	X-ray repair complementing defective repair in Chinese hamster cells 6	0.050
MAPK3	mitogen-activated protein kinase 3	0.046
LATS2	LATS, large tumor suppressor, homolog 2 (Drosophila)	0.045
FBXL12	F-box and leucine-rich repeat protein 12	0.044
NCOA3	nuclear receptor coactivator 3	0.044	Mouse
KAT2B	K(lysine) acetyltransferase 2B	0.043
SKIL	SKI-like oncogene	0.041
NCOA2	nuclear receptor coactivator 2	0.041
INPP5D	inositol polyphosphate-5-phosphatase, 145kDa	0.040
GADD45B	growth arrest and DNA-damage-inducible, beta	0.035
NCOR1	nuclear receptor corepressor 1	0.034
FAM46A	family with sequence similarity 46, member A	0.033
MAPKAPK2	mitogen-activated protein kinase-activated protein kinase 2	0.033
POU5F1	POU class 5 homeobox 1	0.033
EGLN3	egl nine homolog 3 (C. elegans)	0.031
SPOP	speckle-type POZ protein	0.031
PTPN1	protein tyrosine phosphatase, non-receptor type 1	0.030
PKD2	polycystic kidney disease 2 (autosomal dominant)	0.030	Mouse
NOTCH1	notch 1	0.029
ARID1B	AT rich interactive domain 1B (SWI1-like)	0.028
PLAU	plasminogen activator, urokinase	0.028
KRT6B	keratin 6B	0.027
VEGFA	vascular endothelial growth factor A	0.027
PKD1	polycystic kidney disease 1 (autosomal dominant)	0.026	Mouse
YY1	YY1 transcription factor	0.025
SMARCD1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1	0.024
PRKG1	protein kinase, cGMP-dependent, type I	0.024
FGF10	fibroblast growth factor 10	0.023
TNFRSF12A	tumor necrosis factor receptor superfamily, member 12A	0.022
CYR61	cysteine-rich, angiogenic inducer, 61	0.021	Mouse
SMARCC2	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2	0.021
BMPR1B	bone morphogenetic protein receptor, type IB	0.020
RANBP3	RAN binding protein 3	0.020
SMAD2	SMAD family member 2	0.019
SOCS3	suppressor of cytokine signaling 3	0.018	Mouse
SAV1	salvador homolog 1 (Drosophila)	0.018
VDR	vitamin D (1,25- dihydroxyvitamin D3) receptor	0.018
MYC	v-myc myelocytomatosis viral oncogene homolog (avian)	0.016
FOS	FBJ murine osteosarcoma viral oncogene homolog	0.016
RGS2	regulator of G-protein signaling 2, 24kDa	0.016
SH3KBP1	SH3-domain kinase binding protein 1	0.015
BCL2	B-cell CLL/lymphoma 2	0.015
NIPBL	Nipped-B homolog (Drosophila)	0.015
TRRAP	transformation/transcription domain-associated protein	0.014
MAPK8	mitogen-activated protein kinase 8	0.013
CREB1	cAMP responsive element binding protein 1	0.013
PLAT	plasminogen activator, tissue	0.013
PTPN11	protein tyrosine phosphatase, non-receptor type 11	0.013
BAG1	BCL2-associated athanogene	0.013
JAK2	Janus kinase 2	0.012
TCF4	transcription factor 4	0.012
AHR	aryl hydrocarbon receptor	0.012
FGF1	fibroblast growth factor 1 (acidic)	0.012
PGK1	phosphoglycerate kinase 1	0.012
AR	androgen receptor	0.012
MAP1S	microtubule-associated protein 1S	0.012
ARNT	aryl hydrocarbon receptor nuclear translocator	0.012	Mouse
HEYL	hairy/enhancer-of-split related with YRPW motif-like	0.012
PTPRJ	protein tyrosine phosphatase, receptor type, J	0.011
PIAS1	protein inhibitor of activated STAT, 1	0.011
OSMR	oncostatin M receptor	0.011
BHLHE40	basic helix-loop-helix family, member e40	0.011
RXRA	retinoid X receptor, alpha	0.011	Mouse Rat
KRT18	keratin 18	0.011
SQSTM1	sequestosome 1	0.011
ARID1A	AT rich interactive domain 1A (SWI-like)	0.011	Mouse
MAX	MYC associated factor X	0.011
BAG2	BCL2-associated athanogene 2	0.011
HSPB1	heat shock 27kDa protein 1	0.010
CRKL	v-crk sarcoma virus CT10 oncogene homolog (avian)-like	0.010
VHL	von Hippel-Lindau tumor suppressor	0.010
FGF7	fibroblast growth factor 7	0.010