|
|
regulation of cell cycle
|
GO:0051726 |
393 |
1.000
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
189 |
0.998
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.996
|
|
|
|
mitotic sister chromatid segregation
|
GO:0000070 |
53 |
0.988
|
|
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
212 |
0.986
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.984
|
|
|
|
organelle fission
|
GO:0048285 |
149 |
0.981
|
|
|
|
meiotic chromosome segregation
|
GO:0045132 |
4 |
0.975
|
Yeast Worm |
|
|
modification dependent protein catabolic process
|
GO:0019941 |
209 |
0.968
|
|
|
|
mitotic nuclear division
|
GO:0007067 |
119 |
0.968
|
|
|
|
spindle assembly
|
GO:0051225 |
29 |
0.967
|
Yeast Fly |
|
|
nuclear division
|
GO:0000280 |
128 |
0.958
|
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
206 |
0.958
|
|
|
|
dna integrity checkpoint
|
GO:0031570 |
71 |
0.949
|
|
|
|
mitotic cell cycle phase transition
|
GO:0044772 |
162 |
0.947
|
|
|
|
sister chromatid segregation
|
GO:0000819 |
54 |
0.939
|
|
|
|
cell cycle phase transition
|
GO:0044770 |
173 |
0.933
|
|
|
|
proteasomal protein catabolic process
|
GO:0010498 |
176 |
0.931
|
|
|
|
regulation of mitotic metaphase anaphase transition
|
GO:0030071 |
26 |
0.910
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.910
|
|
|
|
negative regulation of cell cycle phase transition
|
GO:1901988 |
89 |
0.896
|
|
|
|
negative regulation of mitotic cell cycle
|
GO:0045930 |
102 |
0.891
|
|
|
|
dna repair
|
GO:0006281 |
198 |
0.890
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
244 |
0.889
|
|
|
|
mitotic cell cycle checkpoint
|
GO:0007093 |
68 |
0.886
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.885
|
|
|
|
double strand break repair
|
GO:0006302 |
101 |
0.882
|
|
|
|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
156 |
0.862
|
|
|
|
regulation of proteasomal protein catabolic process
|
GO:0061136 |
87 |
0.855
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.855
|
Worm |
|
|
regulation of mitotic cell cycle phase transition
|
GO:1901990 |
118 |
0.851
|
|
|
|
positive regulation of mitotic cell cycle
|
GO:0045931 |
60 |
0.844
|
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
176 |
0.818
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
193 |
0.811
|
|
|
|
male meiosis
|
GO:0007140 |
1 |
0.802
|
Fly |
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
380 |
0.792
|
|
|
|
positive regulation of cell division
|
GO:0051781 |
59 |
0.764
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.761
|
|
|
|
negative regulation of cell cycle process
|
GO:0010948 |
121 |
0.744
|
|
|
|
positive regulation of cell cycle
|
GO:0045787 |
140 |
0.714
|
|
|
|
chromosome segregation
|
GO:0007059 |
114 |
0.712
|
|
|
|
positive regulation of mitosis
|
GO:0045840 |
25 |
0.701
|
|
|
|
regulation of cell cycle phase transition
|
GO:1901987 |
126 |
0.698
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
261 |
0.697
|
|
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.659
|
|
|
|
regulation of cell diameter
|
GO:0060305 |
1 |
0.653
|
|
|
|
cytokinesis
|
GO:0000910 |
96 |
0.649
|
|
|
|
spindle organization
|
GO:0007051 |
53 |
0.647
|
Human Yeast Worm Fly |
|
|
mitotic dna integrity checkpoint
|
GO:0044774 |
30 |
0.639
|
|
|
|
positive regulation of cellular protein catabolic process
|
GO:1903364 |
37 |
0.637
|
|
|
|
g2 m transition of mitotic cell cycle
|
GO:0000086 |
41 |
0.623
|
|
|
|
negative regulation of transcription from rna polymerase ii promoter
|
GO:0000122 |
281 |
0.621
|
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
142 |
0.614
|
|
|
|
protein ubiquitination
|
GO:0016567 |
314 |
0.613
|
|
|
|
regulation of cellular protein catabolic process
|
GO:1903362 |
96 |
0.591
|
|
|
|
endomembrane system organization
|
GO:0010256 |
196 |
0.579
|
Human Worm |
|
|
histone serine phosphorylation
|
GO:0035404 |
4 |
0.573
|
|
|
|
regulation of mitosis
|
GO:0007088 |
63 |
0.569
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.562
|
|
|
|
regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903050 |
91 |
0.560
|
|
|
|
cell cycle checkpoint
|
GO:0000075 |
117 |
0.545
|
|
|
|
regulation of chromosome segregation
|
GO:0051983 |
44 |
0.542
|
|
|
|
chromosome separation
|
GO:0051304 |
23 |
0.533
|
|
|
|
dna damage checkpoint
|
GO:0000077 |
68 |
0.517
|
|
|
|
response to radiation
|
GO:0009314 |
151 |
0.515
|
Human |
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.510
|
|
|
|
regulation of cell division
|
GO:0051302 |
116 |
0.498
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.493
|
|
|
|
positive regulation of mitotic sister chromatid separation
|
GO:1901970 |
6 |
0.480
|
|
|
|
oocyte maturation
|
GO:0001556 |
1 |
0.479
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.450
|
|
|
|
metaphase anaphase transition of cell cycle
|
GO:0044784 |
21 |
0.438
|
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.436
|
Worm Fly |
|
|
positive regulation of cell cycle process
|
GO:0090068 |
106 |
0.434
|
|
|
|
regulation of mitotic sister chromatid segregation
|
GO:0033047 |
27 |
0.420
|
|
|
|
mitotic dna damage checkpoint
|
GO:0044773 |
28 |
0.398
|
|
|
|
mitotic cytokinesis
|
GO:0000281 |
19 |
0.390
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.387
|
Worm Fly |
|
|
protein maturation
|
GO:0051604 |
233 |
0.379
|
|
|
|
cell cycle g2 m phase transition
|
GO:0044839 |
43 |
0.367
|
|
|
|
cell division
|
GO:0051301 |
168 |
0.367
|
|
|
|
peptidyl serine modification
|
GO:0018209 |
106 |
0.361
|
|
|
|
positive regulation of protein catabolic process
|
GO:0045732 |
75 |
0.335
|
|
|
|
microtubule based process
|
GO:0007017 |
210 |
0.318
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.310
|
|
|
|
centrosome organization
|
GO:0051297 |
58 |
0.298
|
|
|
|
tube morphogenesis
|
GO:0035239 |
95 |
0.291
|
|
|
|
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic process
|
GO:0031145 |
25 |
0.290
|
|
|
|
maintenance of protein location
|
GO:0045185 |
57 |
0.289
|
|
|
|
negative regulation of mitotic cell cycle phase transition
|
GO:1901991 |
85 |
0.289
|
|
|
|
regulation of proteasomal ubiquitin dependent protein catabolic process
|
GO:0032434 |
71 |
0.288
|
|
|
|
positive regulation of exit from mitosis
|
GO:0031536 |
2 |
0.281
|
|
|
|
centrosome cycle
|
GO:0007098 |
32 |
0.276
|
Human Worm |
|
|
nucleus localization
|
GO:0051647 |
1 |
0.270
|
Fly |
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.260
|
|
|
|
mitotic spindle organization
|
GO:0007052 |
27 |
0.251
|
Human Worm Fly |
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.249
|
|
|
|
cyclin catabolic process
|
GO:0008054 |
6 |
0.238
|
|
|
|
spindle checkpoint
|
GO:0031577 |
26 |
0.233
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
342 |
0.226
|
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
127 |
0.214
|
|
|
|
cell cell signaling
|
GO:0007267 |
155 |
0.205
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.203
|
|
|
|
positive regulation of proteasomal ubiquitin dependent protein catabolic process
|
GO:0032436 |
30 |
0.201
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
177 |
0.199
|
Human Yeast |
|
|
regulation of nuclear division
|
GO:0051783 |
65 |
0.198
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.198
|
|
|
|
spindle assembly checkpoint
|
GO:0071173 |
17 |
0.193
|
|
|
|
attachment of spindle microtubules to kinetochore
|
GO:0008608 |
17 |
0.193
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.189
|
|
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.188
|
|
|
|
negative regulation of protein processing
|
GO:0010955 |
142 |
0.182
|
|
|
|
negative regulation of chromosome organization
|
GO:2001251 |
48 |
0.182
|
|
|
|
negative regulation of cellular catabolic process
|
GO:0031330 |
83 |
0.171
|
|
|
|
positive regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903052 |
35 |
0.156
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
195 |
0.155
|
|
|
|
maintenance of location
|
GO:0051235 |
112 |
0.153
|
|
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.152
|
|
|
|
protein localization to chromosome
|
GO:0034502 |
30 |
0.150
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.147
|
|
|
|
mitotic sister chromatid separation
|
GO:0051306 |
18 |
0.147
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.144
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.143
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.141
|
|
|
|
histone modification
|
GO:0016570 |
251 |
0.137
|
|
|
|
cytoskeleton dependent cytokinesis
|
GO:0061640 |
22 |
0.136
|
|
|
|
microtubule anchoring
|
GO:0034453 |
24 |
0.136
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.135
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.134
|
|
|
|
protein oligomerization
|
GO:0051259 |
173 |
0.133
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.132
|
|
|
|
dna damage response signal transduction by p53 class mediator
|
GO:0030330 |
44 |
0.132
|
|
|
|
cell cycle g1 s phase transition
|
GO:0044843 |
80 |
0.131
|
Human |
|
|
regulation of mitotic sister chromatid separation
|
GO:0010965 |
27 |
0.129
|
|
|
|
maintenance of protein location in cell
|
GO:0032507 |
56 |
0.128
|
|
|
|
positive regulation of ligase activity
|
GO:0051351 |
19 |
0.124
|
|
|
|
nucleus organization
|
GO:0006997 |
28 |
0.123
|
Worm Fly |
|
|
protein k11 linked ubiquitination
|
GO:0070979 |
24 |
0.119
|
|
|
|
organelle assembly
|
GO:0070925 |
176 |
0.116
|
Human Yeast Fly |
|
|
regulation of cell development
|
GO:0060284 |
161 |
0.115
|
Fly |
|
|
regulation of endopeptidase activity
|
GO:0052548 |
170 |
0.115
|
|
|
|
cellular homeostasis
|
GO:0019725 |
196 |
0.115
|
|
|
|
signal transduction by p53 class mediator
|
GO:0072331 |
72 |
0.114
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.113
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.107
|
|
|
|
covalent chromatin modification
|
GO:0016569 |
254 |
0.107
|
|
|
|
double strand break repair via single strand annealing
|
GO:0045002 |
4 |
0.106
|
|
|
|
dna replication
|
GO:0006260 |
116 |
0.104
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.103
|
Human |
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.103
|
|
|
|
regulation of microtubule cytoskeleton organization
|
GO:0070507 |
61 |
0.101
|
Human Yeast |
|
|
cellular component disassembly
|
GO:0022411 |
92 |
0.101
|
Human Yeast Worm |
|
|
sister chromatid cohesion
|
GO:0007062 |
24 |
0.099
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
158 |
0.097
|
|
|
|
meiotic cell cycle
|
GO:0051321 |
13 |
0.095
|
Yeast Rat Worm Fly |
|
|
positive regulation of chromosome segregation
|
GO:0051984 |
9 |
0.093
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.092
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.091
|
Fly |
|
|
positive regulation of chromosome organization
|
GO:2001252 |
41 |
0.091
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
239 |
0.085
|
|
|
|
single organism reproductive process
|
GO:0044702 |
98 |
0.082
|
Worm Fly |
|
|
embryo development
|
GO:0009790 |
123 |
0.082
|
Worm Fly |
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
70 |
0.081
|
|
|
|
gtp catabolic process
|
GO:0006184 |
237 |
0.081
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.080
|
|
|
|
protein polyubiquitination
|
GO:0000209 |
110 |
0.078
|
|
|
|
microtubule organizing center organization
|
GO:0031023 |
62 |
0.078
|
|
|
|
regulation of metaphase anaphase transition of cell cycle
|
GO:1902099 |
26 |
0.078
|
|
|
|
negative regulation of protein catabolic process
|
GO:0042177 |
59 |
0.078
|
|
|
|
histone phosphorylation
|
GO:0016572 |
16 |
0.077
|
|
|
|
protein k48 linked ubiquitination
|
GO:0070936 |
38 |
0.077
|
|
|
|
protein polymerization
|
GO:0051258 |
71 |
0.076
|
Fly |
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
392 |
0.076
|
|
|
|
establishment of nucleus localization
|
GO:0040023 |
1 |
0.075
|
Fly |
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.074
|
|
|
|
membrane organization
|
GO:0061024 |
292 |
0.072
|
Worm |
|
|
protein processing
|
GO:0016485 |
226 |
0.071
|
|
|
|
positive regulation of proteasomal protein catabolic process
|
GO:1901800 |
35 |
0.070
|
|
|
|
positive regulation of mitotic cell cycle phase transition
|
GO:1901992 |
19 |
0.069
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.068
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.067
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.067
|
|
|
|
establishment of organelle localization
|
GO:0051656 |
59 |
0.067
|
Fly |
|
|
positive regulation of metaphase anaphase transition of cell cycle
|
GO:1902101 |
6 |
0.067
|
|
|
|
negative regulation of organelle organization
|
GO:0010639 |
126 |
0.066
|
|
|
|
positive regulation of nuclear division
|
GO:0051785 |
27 |
0.066
|
|
|
|
regulation of meiotic cell cycle
|
GO:0051445 |
4 |
0.065
|
Worm |
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.065
|
|
|
|
aging
|
GO:0007568 |
66 |
0.064
|
|
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.062
|
Human |
|
|
actin filament based process
|
GO:0030029 |
224 |
0.061
|
Fly |
|
|
microtubule nucleation
|
GO:0007020 |
6 |
0.060
|
Fly |
|
|
regulation of protein modification by small protein conjugation or removal
|
GO:1903320 |
107 |
0.060
|
|
|
|
negative regulation of catabolic process
|
GO:0009895 |
104 |
0.058
|
|
|
|
regulation of protein ubiquitination
|
GO:0031396 |
95 |
0.058
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.058
|
|
|
|
dephosphorylation
|
GO:0016311 |
209 |
0.058
|
|
|
|
regulation of response to dna damage stimulus
|
GO:2001020 |
94 |
0.058
|
|
|
|
spindle assembly involved in mitosis
|
GO:0090307 |
12 |
0.057
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.056
|
|
|
|
meiosis i
|
GO:0007127 |
4 |
0.055
|
Yeast Worm |
|
|
epithelium development
|
GO:0060429 |
227 |
0.055
|
Fly |
|
|
regulation of cysteine type endopeptidase activity
|
GO:2000116 |
127 |
0.054
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.054
|
|
|
|
signal transduction in response to dna damage
|
GO:0042770 |
57 |
0.052
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.052
|
|
|
|
positive regulation of cysteine type endopeptidase activity
|
GO:2001056 |
79 |
0.052
|
|
|
|
negative regulation of transport
|
GO:0051051 |
176 |
0.052
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
209 |
0.051
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
412 |
0.051
|
|
|
|
cell aging
|
GO:0007569 |
52 |
0.050
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.050
|
Fly |
|
|
regulation of chromosome organization
|
GO:0033044 |
103 |
0.049
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.049
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
149 |
0.048
|
|
|
|
centrosome separation
|
GO:0051299 |
3 |
0.047
|
|
|
|
regulation of intrinsic apoptotic signaling pathway
|
GO:2001242 |
72 |
0.046
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
140 |
0.046
|
|
|
|
generation of neurons
|
GO:0048699 |
152 |
0.046
|
Fly |
|
|
negative regulation of transferase activity
|
GO:0051348 |
124 |
0.046
|
|
|
|
positive regulation of ubiquitin protein transferase activity
|
GO:0051443 |
18 |
0.045
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
408 |
0.045
|
|
|
|
single organism membrane organization
|
GO:0044802 |
268 |
0.045
|
Worm |
|
|
embryo development ending in birth or egg hatching
|
GO:0009792 |
34 |
0.044
|
Worm |
|
|
microtubule cytoskeleton organization involved in mitosis
|
GO:1902850 |
15 |
0.044
|
|
|
|
recombinational repair
|
GO:0000725 |
50 |
0.044
|
|
|
|
glomerular epithelial cell development
|
GO:0072310 |
3 |
0.043
|
|
|
|
intrinsic apoptotic signaling pathway by p53 class mediator
|
GO:0072332 |
37 |
0.043
|
|
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.042
|
|
|
|
regulation of dna repair
|
GO:0006282 |
47 |
0.042
|
|
|
|
centrosome duplication
|
GO:0051298 |
28 |
0.041
|
Human |
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
244 |
0.041
|
|
|
|
anatomical structure homeostasis
|
GO:0060249 |
100 |
0.041
|
|
|
|
oocyte development
|
GO:0048599 |
1 |
0.040
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.040
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.040
|
Fly |
|
|
organelle localization
|
GO:0051640 |
84 |
0.039
|
Fly |
|
|
negative regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903051 |
35 |
0.039
|
|
|
|
oocyte differentiation
|
GO:0009994 |
2 |
0.039
|
Fly |
|
|
regulation of protein catabolic process
|
GO:0042176 |
155 |
0.038
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
394 |
0.038
|
|
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.037
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.037
|
|
|
|
regulation of dna metabolic process
|
GO:0051052 |
153 |
0.036
|
|
|
|
protein autophosphorylation
|
GO:0046777 |
123 |
0.036
|
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.035
|
|
|
|
myosin filament assembly
|
GO:0031034 |
2 |
0.035
|
|
|
|
positive regulation of ubiquitin protein ligase activity involved in mitotic cell cycle
|
GO:0051437 |
2 |
0.034
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.034
|
Fly |
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.034
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
408 |
0.034
|
|
|
|
response to fungus
|
GO:0009620 |
4 |
0.033
|
|
|
|
negative regulation of protein maturation
|
GO:1903318 |
142 |
0.032
|
|
|
|
maintenance of location in cell
|
GO:0051651 |
62 |
0.032
|
|
|
|
negative regulation of proteolysis
|
GO:0045861 |
132 |
0.032
|
|
|
|
neuron development
|
GO:0048666 |
113 |
0.032
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.032
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.032
|
|
|
|
dna damage response signal transduction resulting in transcription
|
GO:0042772 |
12 |
0.032
|
|
|
|
peptidyl serine phosphorylation
|
GO:0018105 |
101 |
0.032
|
|
|
|
regulation of nervous system development
|
GO:0051960 |
88 |
0.031
|
Fly |
|
|
mapk cascade
|
GO:0000165 |
288 |
0.031
|
|
|
|
negative regulation of chromosome segregation
|
GO:0051985 |
18 |
0.031
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
227 |
0.031
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.030
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
181 |
0.029
|
|
|
|
activation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0006919 |
49 |
0.029
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.029
|
|
|
|
response to nitrogen compound
|
GO:1901698 |
184 |
0.029
|
|
|
|
double strand break repair via homologous recombination
|
GO:0000724 |
50 |
0.028
|
|
|
|
regulation of cell aging
|
GO:0090342 |
18 |
0.028
|
|
|
|
exit from mitosis
|
GO:0010458 |
10 |
0.028
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.028
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.028
|
|
|
|
spermatogenesis
|
GO:0007283 |
22 |
0.028
|
Fly |
|
|
regulation of cytokinesis
|
GO:0032465 |
45 |
0.027
|
Human |
|
|
multi organism reproductive process
|
GO:0044703 |
54 |
0.027
|
Worm Fly |
|
|
negative regulation of mitotic metaphase anaphase transition
|
GO:0045841 |
17 |
0.027
|
|
|
|
nuclear migration
|
GO:0007097 |
1 |
0.027
|
Fly |
|
|
meiotic nuclear division
|
GO:0007126 |
10 |
0.027
|
Yeast Rat Worm Fly |
|
|
cellular response to radiation
|
GO:0071478 |
65 |
0.026
|
|
|
|
endocytosis
|
GO:0006897 |
159 |
0.026
|
Fly |
|
|
regulation of peptidase activity
|
GO:0052547 |
180 |
0.026
|
|
|
|
peptidyl threonine phosphorylation
|
GO:0018107 |
41 |
0.026
|
|
|
|
regulation of dephosphorylation
|
GO:0035303 |
96 |
0.026
|
|
|
|
regulation of cell cycle arrest
|
GO:0071156 |
36 |
0.026
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.026
|
Fly |
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.025
|
Human |
|
|
regeneration
|
GO:0031099 |
4 |
0.025
|
|
|
|
cellular protein complex assembly
|
GO:0043623 |
188 |
0.025
|
Fly |
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.025
|
|
|
|
multicellular organismal reproductive process
|
GO:0048609 |
40 |
0.025
|
Worm Fly |
|
|
negative regulation of kinase activity
|
GO:0033673 |
106 |
0.025
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
101 |
0.024
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.024
|
|
|
|
zymogen activation
|
GO:0031638 |
70 |
0.023
|
|
|
|
regulation of sister chromatid segregation
|
GO:0033045 |
27 |
0.023
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
125 |
0.023
|
|
|
|
g2 dna damage checkpoint
|
GO:0031572 |
26 |
0.023
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.023
|
|
|
|
regulation of protein processing
|
GO:0070613 |
150 |
0.023
|
|
|
|
positive regulation of mitotic metaphase anaphase transition
|
GO:0045842 |
6 |
0.023
|
|
|
|
dna damage response signal transduction by p53 class mediator resulting in transcription of p21 class mediator
|
GO:0006978 |
11 |
0.022
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
230 |
0.022
|
|
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
131 |
0.022
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.022
|
|
|
|
spermatid differentiation
|
GO:0048515 |
4 |
0.022
|
|
|
|
establishment or maintenance of cell polarity
|
GO:0007163 |
31 |
0.022
|
|
|
|
activation of cysteine type endopeptidase activity
|
GO:0097202 |
57 |
0.021
|
|
|
|
dna catabolic process
|
GO:0006308 |
49 |
0.021
|
|
|
|
positive regulation of peptidase activity
|
GO:0010952 |
88 |
0.021
|
|
|
|
nuclear transport
|
GO:0051169 |
179 |
0.021
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
128 |
0.020
|
|
|
|
negative regulation of cell division
|
GO:0051782 |
31 |
0.020
|
|
|
|
regulation of spindle organization
|
GO:0090224 |
10 |
0.020
|
|
|
|
cell projection organization
|
GO:0030030 |
252 |
0.020
|
|
|
|
male gamete generation
|
GO:0048232 |
22 |
0.020
|
Fly |
|
|
myosin filament organization
|
GO:0031033 |
2 |
0.020
|
|
|
|
non recombinational repair
|
GO:0000726 |
14 |
0.019
|
|
|
|
establishment or maintenance of microtubule cytoskeleton polarity
|
GO:0030951 |
2 |
0.019
|
|
|
|
oogenesis
|
GO:0048477 |
2 |
0.019
|
Worm Fly |
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.019
|
Human |
|
|
dna catabolic process exonucleolytic
|
GO:0000738 |
17 |
0.019
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
104 |
0.019
|
|
|
|
establishment of cell polarity
|
GO:0030010 |
22 |
0.019
|
|
|
|
cellular response to abiotic stimulus
|
GO:0071214 |
117 |
0.019
|
|
|
|
striated muscle myosin thick filament assembly
|
GO:0071688 |
2 |
0.019
|
|
|
|
metaphase anaphase transition of mitotic cell cycle
|
GO:0007091 |
21 |
0.019
|
|
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043281 |
116 |
0.018
|
|
|
|
lipid localization
|
GO:0010876 |
106 |
0.018
|
|
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
127 |
0.017
|
|
|
|
muscle organ development
|
GO:0007517 |
56 |
0.017
|
|
|
|
histone acetylation
|
GO:0016573 |
93 |
0.017
|
|
|
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
185 |
0.017
|
|
|
|
regulation of histone modification
|
GO:0031056 |
47 |
0.017
|
|
|
|
nucleotide excision repair dna incision
|
GO:0033683 |
7 |
0.017
|
|
|
|
chemotaxis
|
GO:0006935 |
157 |
0.017
|
|
|
|
regulation of cell cycle g1 s phase transition
|
GO:1902806 |
42 |
0.017
|
|
|
|
regulation of ligase activity
|
GO:0051340 |
29 |
0.017
|
|
|
|
telomere maintenance
|
GO:0000723 |
32 |
0.017
|
|
|
|
chromatin modification
|
GO:0016568 |
298 |
0.016
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
411 |
0.016
|
|
|
|
protein import into nucleus
|
GO:0006606 |
104 |
0.016
|
|
|
|
gtp metabolic process
|
GO:0046039 |
239 |
0.016
|
|
|
|
dna recombination
|
GO:0006310 |
77 |
0.016
|
Yeast |
|
|
regulation of cell adhesion
|
GO:0030155 |
166 |
0.016
|
|
|
|
negative regulation of protein transport
|
GO:0051224 |
75 |
0.016
|
|
|
|
negative regulation of cell size
|
GO:0045792 |
3 |
0.016
|
|
|
|
tube development
|
GO:0035295 |
125 |
0.016
|
Fly |
|
|
positive regulation of cardiac muscle cell proliferation
|
GO:0060045 |
2 |
0.016
|
|
|
|
dna duplex unwinding
|
GO:0032508 |
30 |
0.016
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.016
|
|
|
|
protein targeting
|
GO:0006605 |
187 |
0.015
|
|
|
|
dna geometric change
|
GO:0032392 |
32 |
0.015
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.015
|
|
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
185 |
0.015
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.015
|
|
|
|
negative regulation of mitosis
|
GO:0045839 |
24 |
0.015
|
|
|
|
vesicle organization
|
GO:0016050 |
62 |
0.015
|
|
|
|
g1 s transition of mitotic cell cycle
|
GO:0000082 |
78 |
0.015
|
Human |
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
213 |
0.015
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
205 |
0.015
|
|
|
|
negative regulation of cysteine type endopeptidase activity
|
GO:2000117 |
48 |
0.015
|
|
|
|
regulation of protein maturation
|
GO:1903317 |
150 |
0.015
|
|
|
|
response to uv
|
GO:0009411 |
73 |
0.015
|
|
|
|
activation of protein kinase activity
|
GO:0032147 |
90 |
0.014
|
|
|
|
digestive system development
|
GO:0055123 |
75 |
0.014
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
207 |
0.014
|
Fly |
|
|
ribonucleotide catabolic process
|
GO:0009261 |
405 |
0.014
|
|
|
|
positive regulation of protein ubiquitination
|
GO:0031398 |
53 |
0.014
|
|
|
|
regulation of canonical wnt signaling pathway
|
GO:0060828 |
88 |
0.014
|
|
|
|
protein sumoylation
|
GO:0016925 |
25 |
0.014
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
181 |
0.014
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.014
|
|
|
|
intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediator
|
GO:0042771 |
23 |
0.014
|
|
|
|
regulation of ubiquitin protein transferase activity
|
GO:0051438 |
28 |
0.014
|
|
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.014
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
162 |
0.014
|
|
|
|
positive regulation of endopeptidase activity
|
GO:0010950 |
84 |
0.014
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.013
|
|
|
|
response to ionizing radiation
|
GO:0010212 |
65 |
0.013
|
|
|
|
immune response
|
GO:0006955 |
307 |
0.013
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
135 |
0.013
|
|
|
|
negative regulation of dna metabolic process
|
GO:0051053 |
57 |
0.013
|
|
|
|
negative regulation of protein kinase activity
|
GO:0006469 |
98 |
0.013
|
|
|
|
reproductive process
|
GO:0022414 |
106 |
0.013
|
Worm Fly |
|
|
gland development
|
GO:0048732 |
48 |
0.013
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.013
|
|
|
|
regulation of homeostatic process
|
GO:0032844 |
121 |
0.013
|
|
|
|
negative regulation of neurogenesis
|
GO:0050768 |
26 |
0.012
|
Fly |
|
|
regulation of protein binding
|
GO:0043393 |
66 |
0.012
|
|
|
|
sexual reproduction
|
GO:0019953 |
37 |
0.012
|
Worm Fly |
|
|
positive regulation of dna metabolic process
|
GO:0051054 |
73 |
0.012
|
|
|
|
cytokinetic process
|
GO:0032506 |
12 |
0.012
|
Fly |
|
|
negative regulation of peptidase activity
|
GO:0010466 |
91 |
0.012
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
92 |
0.012
|
|
|
|
regulation of synaptic plasticity
|
GO:0048167 |
3 |
0.012
|
|
|
|
regulation of cytokine mediated signaling pathway
|
GO:0001959 |
41 |
0.012
|
|
|
|
receptor mediated endocytosis
|
GO:0006898 |
84 |
0.012
|
|
|
|
taxis
|
GO:0042330 |
157 |
0.012
|
|
|
|
organ morphogenesis
|
GO:0009887 |
147 |
0.012
|
|
|
|
positive regulation of immune response
|
GO:0050778 |
159 |
0.012
|
|
|
|
neuronal stem cell maintenance
|
GO:0097150 |
5 |
0.012
|
|
|
|
regulation of protein dephosphorylation
|
GO:0035304 |
18 |
0.011
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.011
|
|
|
|
protein k63 linked ubiquitination
|
GO:0070534 |
31 |
0.011
|
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
180 |
0.011
|
|
|
|
single organism nuclear import
|
GO:1902593 |
104 |
0.011
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.011
|
|
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.011
|
Human |
|
|
response to organonitrogen compound
|
GO:0010243 |
156 |
0.011
|
|
|
|
cell part morphogenesis
|
GO:0032990 |
137 |
0.011
|
|
|
|
chromatin organization
|
GO:0006325 |
351 |
0.011
|
|
|
|
protein tetramerization
|
GO:0051262 |
47 |
0.011
|
|
|
|
regulation of microtubule based process
|
GO:0032886 |
74 |
0.011
|
Human Yeast |
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
398 |
0.011
|
|
|
|
regulation of centrosome cycle
|
GO:0046605 |
15 |
0.011
|
Human |
|
|
positive regulation of cytokinesis
|
GO:0032467 |
29 |
0.011
|
|
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.011
|
|
|
|
negative regulation of metaphase anaphase transition of cell cycle
|
GO:1902100 |
17 |
0.010
|
|
|
|
response to oxygen levels
|
GO:0070482 |
100 |
0.010
|
Human |
|
|
sex differentiation
|
GO:0007548 |
45 |
0.010
|
Worm |
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
182 |
0.010
|
|
|
|
positive regulation of protein complex assembly
|
GO:0031334 |
86 |
0.010
|
|
|
|
negative regulation of dephosphorylation
|
GO:0035305 |
63 |
0.010
|
|
|
|
protein homotetramerization
|
GO:0051289 |
28 |
0.010
|
|
|
|
response to oxidative stress
|
GO:0006979 |
121 |
0.010
|
Human |
