|
|
regulation of cell cycle arrest
|
GO:0071156 |
36 |
1.000
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.987
|
|
|
|
hippo signaling
|
GO:0035329 |
20 |
0.986
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.973
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.953
|
|
|
|
regulation of protein ubiquitination
|
GO:0031396 |
95 |
0.937
|
|
|
|
regulation of protein modification by small protein conjugation or removal
|
GO:1903320 |
107 |
0.911
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
342 |
0.905
|
|
|
|
peptidyl serine modification
|
GO:0018209 |
106 |
0.898
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.894
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
119 |
0.890
|
Mouse |
|
|
protein stabilization
|
GO:0050821 |
64 |
0.889
|
Human |
|
|
regulation of protein stability
|
GO:0031647 |
87 |
0.851
|
Human |
|
|
neural tube formation
|
GO:0001841 |
3 |
0.849
|
Mouse |
|
|
positive regulation of jnk cascade
|
GO:0046330 |
52 |
0.844
|
|
|
|
embryonic placenta development
|
GO:0001892 |
1 |
0.842
|
Mouse |
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.837
|
|
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
4 |
0.828
|
Mouse |
|
|
negative regulation of cell cycle arrest
|
GO:0071157 |
12 |
0.781
|
|
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.776
|
Worm |
|
|
cell type specific apoptotic process
|
GO:0097285 |
125 |
0.770
|
Mouse |
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
213 |
0.762
|
Human |
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.751
|
|
|
|
regulation of jnk cascade
|
GO:0046328 |
73 |
0.751
|
|
|
|
negative regulation of wnt signaling pathway
|
GO:0030178 |
69 |
0.751
|
|
|
|
positive regulation of extrinsic apoptotic signaling pathway via death domain receptors
|
GO:1902043 |
3 |
0.729
|
Mouse |
|
|
protein autophosphorylation
|
GO:0046777 |
123 |
0.695
|
|
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
70 |
0.678
|
Mouse |
|
|
canonical wnt signaling pathway
|
GO:0060070 |
116 |
0.671
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.670
|
|
|
|
cell cycle arrest
|
GO:0007050 |
71 |
0.668
|
|
|
|
tube morphogenesis
|
GO:0035239 |
95 |
0.667
|
Mouse |
|
|
embryonic epithelial tube formation
|
GO:0001838 |
4 |
0.648
|
Mouse |
|
|
mapk cascade
|
GO:0000165 |
288 |
0.632
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
0.631
|
|
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.612
|
Worm |
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.609
|
Mouse |
|
|
protein ubiquitination
|
GO:0016567 |
314 |
0.599
|
|
|
|
growth
|
GO:0040007 |
202 |
0.589
|
Mouse |
|
|
generation of neurons
|
GO:0048699 |
152 |
0.579
|
|
|
|
negative regulation of glial cell proliferation
|
GO:0060253 |
2 |
0.553
|
|
|
|
jnk cascade
|
GO:0007254 |
80 |
0.536
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.516
|
|
|
|
positive regulation of stress activated mapk cascade
|
GO:0032874 |
60 |
0.511
|
|
|
|
positive regulation of extrinsic apoptotic signaling pathway
|
GO:2001238 |
26 |
0.489
|
Mouse |
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
175 |
0.477
|
Mouse |
|
|
peptidyl serine phosphorylation
|
GO:0018105 |
101 |
0.477
|
|
|
|
regulation of growth
|
GO:0040008 |
165 |
0.473
|
Mouse |
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.467
|
|
|
|
regulation of cardiac muscle cell proliferation
|
GO:0060043 |
4 |
0.445
|
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.438
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
70 |
0.429
|
|
|
|
hemopoiesis
|
GO:0030097 |
180 |
0.405
|
Mouse |
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
85 |
0.395
|
Mouse |
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
94 |
0.385
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.377
|
|
|
|
epithelial tube morphogenesis
|
GO:0060562 |
38 |
0.373
|
Mouse |
|
|
regulation of stress activated protein kinase signaling cascade
|
GO:0070302 |
85 |
0.373
|
|
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
84 |
0.369
|
|
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
131 |
0.368
|
Human |
|
|
embryonic hemopoiesis
|
GO:0035162 |
4 |
0.358
|
Mouse |
|
|
regulation of cell morphogenesis
|
GO:0022604 |
153 |
0.350
|
|
|
|
neuron projection development
|
GO:0031175 |
106 |
0.340
|
|
|
|
camp biosynthetic process
|
GO:0006171 |
47 |
0.322
|
|
|
|
tube development
|
GO:0035295 |
125 |
0.316
|
Mouse |
|
|
negative regulation of cell cycle process
|
GO:0010948 |
121 |
0.314
|
|
|
|
positive regulation of protein kinase b signaling
|
GO:0051897 |
42 |
0.311
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.296
|
|
|
|
regulation of fat cell differentiation
|
GO:0045598 |
23 |
0.291
|
|
|
|
regulation of cell development
|
GO:0060284 |
161 |
0.288
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.288
|
Worm |
|
|
positive regulation of protein ubiquitination
|
GO:0031398 |
53 |
0.281
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.277
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
156 |
0.275
|
|
|
|
protein kinase b signaling
|
GO:0043491 |
69 |
0.274
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
193 |
0.271
|
|
|
|
response to ionizing radiation
|
GO:0010212 |
65 |
0.270
|
|
|
|
regulation of dendrite development
|
GO:0050773 |
18 |
0.266
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
107 |
0.266
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.256
|
|
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.253
|
Mouse |
|
|
muscle fiber development
|
GO:0048747 |
16 |
0.253
|
Worm |
|
|
oocyte differentiation
|
GO:0009994 |
2 |
0.248
|
|
|
|
immune system development
|
GO:0002520 |
195 |
0.245
|
Mouse |
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.242
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.229
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
211 |
0.225
|
Human |
|
|
positive regulation of protein modification by small protein conjugation or removal
|
GO:1903322 |
61 |
0.224
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.223
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.222
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.213
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.206
|
|
|
|
establishment or maintenance of cytoskeleton polarity
|
GO:0030952 |
3 |
0.205
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.200
|
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.199
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.191
|
|
|
|
rap protein signal transduction
|
GO:0032486 |
7 |
0.191
|
|
|
|
cardiovascular system development
|
GO:0072358 |
262 |
0.190
|
Mouse |
|
|
negative regulation of striated muscle tissue development
|
GO:0045843 |
11 |
0.181
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.180
|
Mouse |
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.177
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.175
|
|
|
|
endocardium development
|
GO:0003157 |
2 |
0.175
|
Mouse |
|
|
neural tube development
|
GO:0021915 |
9 |
0.175
|
Mouse |
|
|
central nervous system development
|
GO:0007417 |
123 |
0.174
|
Mouse |
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
391 |
0.167
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.166
|
|
|
|
regulation of nervous system development
|
GO:0051960 |
88 |
0.164
|
|
|
|
tissue morphogenesis
|
GO:0048729 |
96 |
0.164
|
Mouse |
|
|
regulation of neurogenesis
|
GO:0050767 |
82 |
0.161
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
113 |
0.159
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
63 |
0.158
|
Worm |
|
|
positive regulation of stress activated protein kinase signaling cascade
|
GO:0070304 |
61 |
0.157
|
|
|
|
digestive system development
|
GO:0055123 |
75 |
0.156
|
|
|
|
adenylate cyclase activating g protein coupled receptor signaling pathway
|
GO:0007189 |
18 |
0.156
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
26 |
0.152
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.148
|
|
|
|
organ growth
|
GO:0035265 |
12 |
0.139
|
Mouse |
|
|
cell part morphogenesis
|
GO:0032990 |
137 |
0.139
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.139
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.136
|
|
|
|
negative regulation of rho gtpase activity
|
GO:0034259 |
4 |
0.133
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.128
|
|
|
|
muscle cell development
|
GO:0055001 |
29 |
0.128
|
Worm |
|
|
positive regulation of fat cell differentiation
|
GO:0045600 |
12 |
0.128
|
|
|
|
striated muscle cell differentiation
|
GO:0051146 |
43 |
0.125
|
Worm |
|
|
locomotory behavior
|
GO:0007626 |
1 |
0.124
|
|
|
|
striated muscle cell development
|
GO:0055002 |
27 |
0.124
|
Worm |
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.119
|
|
|
|
regulation of protein binding
|
GO:0043393 |
66 |
0.117
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.113
|
|
|
|
fat cell differentiation
|
GO:0045444 |
32 |
0.108
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.107
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
140 |
0.104
|
|
|
|
muscle structure development
|
GO:0061061 |
98 |
0.101
|
Worm |
|
|
gtp catabolic process
|
GO:0006184 |
237 |
0.100
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
404 |
0.100
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
128 |
0.100
|
|
|
|
regulation of heart growth
|
GO:0060420 |
4 |
0.100
|
|
|
|
negative regulation of cell differentiation
|
GO:0045596 |
171 |
0.099
|
|
|
|
response to hormone
|
GO:0009725 |
175 |
0.094
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.094
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.092
|
|
|
|
positive regulation of rap gtpase activity
|
GO:0032854 |
8 |
0.092
|
|
|
|
peripheral nervous system development
|
GO:0007422 |
2 |
0.090
|
|
|
|
negative regulation of cellular catabolic process
|
GO:0031330 |
83 |
0.089
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
108 |
0.088
|
|
|
|
rna processing
|
GO:0006396 |
255 |
0.088
|
|
|
|
negative regulation of growth
|
GO:0045926 |
97 |
0.088
|
Mouse |
|
|
regulation of protein kinase b signaling
|
GO:0051896 |
61 |
0.086
|
|
|
|
replicative cell aging
|
GO:0001302 |
3 |
0.086
|
|
|
|
regulation of dendrite morphogenesis
|
GO:0048814 |
11 |
0.083
|
|
|
|
epithelium development
|
GO:0060429 |
227 |
0.082
|
Mouse |
|
|
stress activated mapk cascade
|
GO:0051403 |
93 |
0.081
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.080
|
|
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.079
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.078
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.076
|
|
|
|
regulation of developmental growth
|
GO:0048638 |
30 |
0.075
|
Mouse |
|
|
erk1 and erk2 cascade
|
GO:0070371 |
104 |
0.073
|
|
|
|
reproductive process
|
GO:0022414 |
106 |
0.073
|
Mouse |
|
|
positive regulation of protein binding
|
GO:0032092 |
24 |
0.071
|
|
|
|
embryonic camera type eye development
|
GO:0031076 |
2 |
0.069
|
|
|
|
negative regulation of protein serine threonine kinase activity
|
GO:0071901 |
57 |
0.068
|
|
|
|
embryonic morphogenesis
|
GO:0048598 |
85 |
0.067
|
Mouse |
|
|
regulation of exocytosis
|
GO:0017157 |
46 |
0.067
|
|
|
|
regulation of cyclin dependent protein serine threonine kinase activity
|
GO:0000079 |
36 |
0.067
|
|
|
|
actin filament based process
|
GO:0030029 |
224 |
0.065
|
|
|
|
execution phase of apoptosis
|
GO:0097194 |
32 |
0.065
|
|
|
|
neurogenesis
|
GO:0022008 |
169 |
0.065
|
|
|
|
regulation of fatty acid beta oxidation
|
GO:0031998 |
8 |
0.064
|
|
|
|
oocyte development
|
GO:0048599 |
1 |
0.062
|
|
|
|
positive regulation of ruffle assembly
|
GO:1900029 |
4 |
0.062
|
|
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.061
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.061
|
|
|
|
lens development in camera type eye
|
GO:0002088 |
2 |
0.061
|
|
|
|
positive regulation of immune system process
|
GO:0002684 |
283 |
0.061
|
|
|
|
negative regulation of developmental growth
|
GO:0048640 |
10 |
0.061
|
Mouse |
|
|
reproductive system development
|
GO:0061458 |
56 |
0.060
|
Mouse |
|
|
sister chromatid segregation
|
GO:0000819 |
54 |
0.057
|
|
|
|
monocarboxylic acid metabolic process
|
GO:0032787 |
185 |
0.057
|
|
|
|
eye development
|
GO:0001654 |
42 |
0.057
|
|
|
|
regulation of extrinsic apoptotic signaling pathway via death domain receptors
|
GO:1902041 |
24 |
0.056
|
Mouse |
|
|
negative regulation of organ growth
|
GO:0046621 |
5 |
0.056
|
Mouse |
|
|
organ morphogenesis
|
GO:0009887 |
147 |
0.055
|
|
|
|
positive regulation of erk1 and erk2 cascade
|
GO:0070374 |
75 |
0.053
|
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
127 |
0.053
|
|
|
|
positive regulation of epithelial cell proliferation
|
GO:0050679 |
65 |
0.052
|
|
|
|
activation of immune response
|
GO:0002253 |
114 |
0.051
|
|
|
|
negative regulation of ras gtpase activity
|
GO:0034261 |
6 |
0.051
|
|
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.050
|
|
|
|
positive regulation of interleukin 5 production
|
GO:0032754 |
3 |
0.050
|
|
|
|
lung cell differentiation
|
GO:0060479 |
1 |
0.050
|
|
|
|
membrane lipid metabolic process
|
GO:0006643 |
53 |
0.050
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
136 |
0.049
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.049
|
|
|
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
116 |
0.049
|
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
166 |
0.049
|
|
|
|
multicellular organism growth
|
GO:0035264 |
8 |
0.048
|
|
|
|
positive regulation of interleukin 13 production
|
GO:0032736 |
4 |
0.048
|
|
|
|
response to radiation
|
GO:0009314 |
151 |
0.047
|
|
|
|
regulation of rap protein signal transduction
|
GO:0032487 |
9 |
0.047
|
|
|
|
negative regulation of transcription from rna polymerase ii promoter
|
GO:0000122 |
281 |
0.047
|
|
|
|
regulation of multicellular organism growth
|
GO:0040014 |
8 |
0.047
|
|
|
|
developmental process involved in reproduction
|
GO:0003006 |
66 |
0.046
|
Mouse |
|
|
ventricular septum morphogenesis
|
GO:0060412 |
3 |
0.046
|
|
|
|
cytokinesis
|
GO:0000910 |
96 |
0.046
|
|
|
|
positive regulation of peptidyl serine phosphorylation
|
GO:0033138 |
42 |
0.045
|
|
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
324 |
0.044
|
|
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
127 |
0.044
|
|
|
|
regulation of myeloid leukocyte mediated immunity
|
GO:0002886 |
4 |
0.044
|
|
|
|
negative regulation of protein kinase activity
|
GO:0006469 |
98 |
0.044
|
|
|
|
regulation of cell morphogenesis involved in differentiation
|
GO:0010769 |
83 |
0.042
|
|
|
|
cell cycle phase transition
|
GO:0044770 |
173 |
0.042
|
|
|
|
positive regulation of wnt signaling pathway
|
GO:0030177 |
54 |
0.042
|
|
|
|
lipid modification
|
GO:0030258 |
84 |
0.042
|
|
|
|
lipid catabolic process
|
GO:0016042 |
84 |
0.042
|
|
|
|
compound eye development
|
GO:0048749 |
1 |
0.040
|
|
|
|
aging
|
GO:0007568 |
66 |
0.038
|
Worm |
|
|
circulatory system development
|
GO:0072359 |
262 |
0.038
|
Mouse |
|
|
negative regulation of canonical wnt signaling pathway
|
GO:0090090 |
55 |
0.038
|
|
|
|
immune response activating signal transduction
|
GO:0002757 |
90 |
0.038
|
|
|
|
negative regulation of cardiac muscle tissue growth
|
GO:0055022 |
2 |
0.038
|
|
|
|
regulation of secretion
|
GO:0051046 |
194 |
0.037
|
|
|
|
chordate embryonic development
|
GO:0043009 |
34 |
0.037
|
Mouse |
|
|
autophagy
|
GO:0006914 |
88 |
0.037
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
303 |
0.037
|
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.037
|
|
|
|
gliogenesis
|
GO:0042063 |
21 |
0.037
|
|
|
|
skin development
|
GO:0043588 |
76 |
0.037
|
Mouse |
|
|
embryo development
|
GO:0009790 |
123 |
0.037
|
Mouse |
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.036
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
3 |
0.036
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.035
|
|
|
|
sensory organ development
|
GO:0007423 |
52 |
0.035
|
|
|
|
regulation of cell growth
|
GO:0001558 |
135 |
0.035
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
408 |
0.035
|
|
|
|
regulation of synaptic vesicle transport
|
GO:1902803 |
3 |
0.035
|
|
|
|
secretion by cell
|
GO:0032940 |
226 |
0.035
|
|
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.035
|
|
|
|
peptidyl threonine modification
|
GO:0018210 |
45 |
0.034
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
162 |
0.034
|
Mouse |
|
|
blood circulation
|
GO:0008015 |
113 |
0.033
|
|
|
|
establishment or maintenance of actin cytoskeleton polarity
|
GO:0030950 |
1 |
0.033
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.033
|
|
|
|
trachea development
|
GO:0060438 |
1 |
0.033
|
|
|
|
intrinsic apoptotic signaling pathway by p53 class mediator
|
GO:0072332 |
37 |
0.032
|
|
|
|
establishment or maintenance of microtubule cytoskeleton polarity
|
GO:0030951 |
2 |
0.032
|
|
|
|
developmental growth
|
GO:0048589 |
48 |
0.031
|
Mouse |
|
|
carboxylic acid catabolic process
|
GO:0046395 |
71 |
0.031
|
|
|
|
response to gamma radiation
|
GO:0010332 |
14 |
0.031
|
|
|
|
positive regulation of cell size
|
GO:0045793 |
3 |
0.031
|
|
|
|
positive regulation of immune response
|
GO:0050778 |
159 |
0.030
|
|
|
|
regulation of protein localization to nucleus
|
GO:1900180 |
85 |
0.030
|
|
|
|
mrna metabolic process
|
GO:0016071 |
175 |
0.030
|
|
|
|
oogenesis
|
GO:0048477 |
2 |
0.030
|
|
|
|
cell death in response to oxidative stress
|
GO:0036473 |
29 |
0.030
|
|
|
|
cell aging
|
GO:0007569 |
52 |
0.030
|
|
|
|
g1 s transition of mitotic cell cycle
|
GO:0000082 |
78 |
0.030
|
|
|
|
negative regulation of heart growth
|
GO:0061117 |
2 |
0.030
|
|
|
|
cell matrix adhesion
|
GO:0007160 |
85 |
0.029
|
|
|
|
digestive tract development
|
GO:0048565 |
75 |
0.029
|
|
|
|
nucleotide biosynthetic process
|
GO:0009165 |
109 |
0.029
|
|
|
|
nucleoside phosphate biosynthetic process
|
GO:1901293 |
109 |
0.029
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
98 |
0.028
|
|
|
|
activation of protein kinase activity
|
GO:0032147 |
90 |
0.028
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.028
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
124 |
0.028
|
|
|
|
ion transmembrane transport
|
GO:0034220 |
338 |
0.028
|
|
|
|
response to cytokine
|
GO:0034097 |
232 |
0.027
|
|
|
|
ribose phosphate biosynthetic process
|
GO:0046390 |
82 |
0.027
|
|
|
|
regulation of peptidyl serine phosphorylation
|
GO:0033135 |
50 |
0.027
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
2 |
0.027
|
|
|
|
protein processing
|
GO:0016485 |
226 |
0.027
|
|
|
|
neuromuscular junction development
|
GO:0007528 |
3 |
0.026
|
|
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
41 |
0.026
|
|
|
|
regulation of excitatory postsynaptic membrane potential
|
GO:0060079 |
1 |
0.026
|
|
|
|
positive regulation of glucosylceramide catabolic process
|
GO:2000753 |
1 |
0.026
|
|
|
|
regulation of mismatch repair
|
GO:0032423 |
2 |
0.026
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
177 |
0.026
|
|
|
|
rna 3 end processing
|
GO:0031123 |
35 |
0.026
|
|
|
|
neurotransmitter secretion
|
GO:0007269 |
4 |
0.026
|
|
|
|
hair cycle
|
GO:0042633 |
28 |
0.026
|
|
|
|
negative regulation of mapk cascade
|
GO:0043409 |
56 |
0.026
|
|
|
|
cell projection morphogenesis
|
GO:0048858 |
129 |
0.026
|
|
|
|
cellular lipid catabolic process
|
GO:0044242 |
65 |
0.025
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
204 |
0.025
|
|
|
|
inorganic cation transmembrane transport
|
GO:0098662 |
194 |
0.025
|
|
|
|
cellular response to nitrogen compound
|
GO:1901699 |
144 |
0.025
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
119 |
0.025
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.025
|
|
|
|
organelle localization
|
GO:0051640 |
84 |
0.025
|
|
|
|
single organism reproductive process
|
GO:0044702 |
98 |
0.025
|
Mouse |
|
|
intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediator
|
GO:0042771 |
23 |
0.025
|
|
|
|
meiotic chromosome segregation
|
GO:0045132 |
4 |
0.025
|
|
|
|
lymphocyte activation
|
GO:0046649 |
133 |
0.024
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
239 |
0.024
|
|
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.024
|
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
130 |
0.024
|
|
|
|
positive regulation of superoxide anion generation
|
GO:0032930 |
4 |
0.024
|
|
|
|
muscle cell proliferation
|
GO:0033002 |
35 |
0.024
|
|
|
|
leukocyte activation
|
GO:0045321 |
164 |
0.024
|
|
|
|
intracellular receptor signaling pathway
|
GO:0030522 |
104 |
0.024
|
|
|
|
activation of mapkk activity
|
GO:0000186 |
18 |
0.024
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.024
|
|
|
|
immune response
|
GO:0006955 |
307 |
0.024
|
|
|
|
neuron projection morphogenesis
|
GO:0048812 |
50 |
0.024
|
|
|
|
cell activation
|
GO:0001775 |
213 |
0.023
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.023
|
|
|
|
response to alcohol
|
GO:0097305 |
64 |
0.023
|
|
|
|
purine containing compound biosynthetic process
|
GO:0072522 |
88 |
0.023
|
|
|
|
regeneration
|
GO:0031099 |
4 |
0.023
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.023
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
101 |
0.023
|
|
|
|
phospholipid catabolic process
|
GO:0009395 |
12 |
0.023
|
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
125 |
0.023
|
|
|
|
regulation of system process
|
GO:0044057 |
101 |
0.023
|
|
|
|
cell projection organization
|
GO:0030030 |
252 |
0.022
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.022
|
|
|
|
retrograde transport endosome to golgi
|
GO:0042147 |
45 |
0.022
|
|
|
|
lung epithelial cell differentiation
|
GO:0060487 |
1 |
0.022
|
|
|
|
neuron development
|
GO:0048666 |
113 |
0.022
|
|
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.022
|
|
|
|
response to salt stress
|
GO:0009651 |
3 |
0.022
|
|
|
|
positive regulation of reactive oxygen species biosynthetic process
|
GO:1903428 |
2 |
0.022
|
|
|
|
heart development
|
GO:0007507 |
95 |
0.022
|
Mouse |
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
392 |
0.022
|
|
|
|
response to axon injury
|
GO:0048678 |
1 |
0.022
|
|
|
|
camp metabolic process
|
GO:0046058 |
61 |
0.021
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.021
|
|
|
|
regulation of synaptic vesicle exocytosis
|
GO:2000300 |
2 |
0.021
|
|
|
|
negative regulation of cell migration
|
GO:0030336 |
102 |
0.021
|
|
|
|
positive regulation of small gtpase mediated signal transduction
|
GO:0051057 |
12 |
0.021
|
|
|
|
signal transduction by p53 class mediator
|
GO:0072331 |
72 |
0.021
|
|
|
|
focal adhesion assembly
|
GO:0048041 |
30 |
0.021
|
|
|
|
circulatory system process
|
GO:0003013 |
113 |
0.021
|
|
|
|
negative regulation of macroautophagy
|
GO:0016242 |
4 |
0.021
|
|
|
|
regulation of immune response
|
GO:0050776 |
201 |
0.021
|
|
|
|
cellular response to granulocyte macrophage colony stimulating factor stimulus
|
GO:0097011 |
3 |
0.021
|
|
|
|
rna catabolic process
|
GO:0006401 |
71 |
0.021
|
|
|
|
morphogenesis of an epithelium
|
GO:0002009 |
60 |
0.021
|
Mouse |
|
|
positive regulation of defense response
|
GO:0031349 |
87 |
0.020
|
|
|
|
regulation of cellular component size
|
GO:0032535 |
82 |
0.020
|
|
|
|
regulation of i kappab kinase nf kappab signaling
|
GO:0043122 |
162 |
0.020
|
|
|
|
regulation of mrna processing
|
GO:0050684 |
48 |
0.020
|
|
|
|
regulation of neurotransmitter secretion
|
GO:0046928 |
3 |
0.020
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
207 |
0.020
|
|
|
|
cell cell signaling
|
GO:0007267 |
155 |
0.020
|
|
|
|
negative regulation of synaptic transmission
|
GO:0050805 |
2 |
0.020
|
|
|
|
reactive oxygen species biosynthetic process
|
GO:1903409 |
4 |
0.020
|
|
|
|
mrna catabolic process
|
GO:0006402 |
56 |
0.020
|
|
|
|
positive regulation of alpha beta t cell differentiation
|
GO:0046638 |
4 |
0.020
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.020
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.020
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
75 |
0.020
|
|
|
|
divalent inorganic cation transport
|
GO:0072511 |
158 |
0.019
|
|
|
|
response to oxygen levels
|
GO:0070482 |
100 |
0.019
|
|
|
|
single organism carbohydrate metabolic process
|
GO:0044723 |
193 |
0.019
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.019
|
|
|
|
lymphocyte homeostasis
|
GO:0002260 |
4 |
0.019
|
|
|
|
cell cycle g1 s phase transition
|
GO:0044843 |
80 |
0.019
|
|
|
|
regulation of organ growth
|
GO:0046620 |
7 |
0.019
|
Mouse |
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.019
|
|
|
|
response to nitrogen compound
|
GO:1901698 |
184 |
0.019
|
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
97 |
0.019
|
|
|
|
immune response regulating signaling pathway
|
GO:0002764 |
97 |
0.019
|
|
|
|
brain development
|
GO:0007420 |
97 |
0.018
|
|
|
|
small molecule catabolic process
|
GO:0044282 |
92 |
0.018
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.018
|
Mouse |
|
|
negative regulation of nucleotide metabolic process
|
GO:0045980 |
29 |
0.018
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
207 |
0.018
|
|
|
|
sphingolipid metabolic process
|
GO:0006665 |
38 |
0.018
|
|
|
|
mitochondrion distribution
|
GO:0048311 |
3 |
0.018
|
|
|
|
microtubule based process
|
GO:0007017 |
210 |
0.018
|
|
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
200 |
0.018
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.018
|
|
|
|
regulation of dephosphorylation
|
GO:0035303 |
96 |
0.018
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
244 |
0.018
|
|
|
|
epithelial tube formation
|
GO:0072175 |
5 |
0.018
|
Mouse |
|
|
cd4 positive alpha beta t cell differentiation
|
GO:0043367 |
4 |
0.018
|
|
|
|
mitochondrion organization
|
GO:0007005 |
156 |
0.018
|
|
|
|
inorganic ion transmembrane transport
|
GO:0098660 |
231 |
0.018
|
|
|
|
transmembrane transport
|
GO:0055085 |
399 |
0.018
|
|
|
|
positive regulation of rho gtpase activity
|
GO:0032321 |
56 |
0.017
|
|
|
|
regulation of muscle tissue development
|
GO:1901861 |
26 |
0.017
|
|
|
|
regulation of rho protein signal transduction
|
GO:0035023 |
79 |
0.017
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.017
|
|
|
|
cellular response to starvation
|
GO:0009267 |
58 |
0.017
|
|
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.017
|
|
|
|
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger
|
GO:0007187 |
43 |
0.017
|
|
|
|
regulation of lipid catabolic process
|
GO:0050994 |
23 |
0.017
|
|
|
|
establishment or maintenance of cell polarity
|
GO:0007163 |
31 |
0.017
|
|
|
|
protein oligomerization
|
GO:0051259 |
173 |
0.017
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
205 |
0.017
|
|
|
|
negative regulation of epithelial cell proliferation
|
GO:0050680 |
48 |
0.017
|
|
|
|
regulation of mrna metabolic process
|
GO:1903311 |
53 |
0.017
|
|
|
|
positive regulation of cell projection organization
|
GO:0031346 |
64 |
0.017
|
|
|
|
negative regulation of lipid catabolic process
|
GO:0050995 |
9 |
0.017
|
|
|
|
g2 dna damage checkpoint
|
GO:0031572 |
26 |
0.017
|
|
|
|
calcium ion transmembrane transport
|
GO:0070588 |
76 |
0.017
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.017
|
|
|
|
ncrna metabolic process
|
GO:0034660 |
108 |
0.017
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.017
|
|
|
|
negative regulation of t cell apoptotic process
|
GO:0070233 |
4 |
0.017
|
|
|
|
cd4 positive alpha beta t cell differentiation involved in immune response
|
GO:0002294 |
4 |
0.017
|
|
|
|
adenylate cyclase modulating g protein coupled receptor signaling pathway
|
GO:0007188 |
43 |
0.017
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
261 |
0.016
|
|
|
|
regulation of synaptic transmission
|
GO:0050804 |
11 |
0.016
|
|
|
|
activation induced cell death of t cells
|
GO:0006924 |
2 |
0.016
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
172 |
0.016
|
|
|
|
spongiotrophoblast layer development
|
GO:0060712 |
1 |
0.016
|
|
|
|
mast cell activation involved in immune response
|
GO:0002279 |
4 |
0.016
|
|
|
|
fatty acid metabolic process
|
GO:0006631 |
115 |
0.016
|
|
|
|
synaptic vesicle exocytosis
|
GO:0016079 |
3 |
0.016
|
|
|
|
cyclic purine nucleotide metabolic process
|
GO:0052652 |
60 |
0.016
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.016
|
|
|
|
cyclic nucleotide biosynthetic process
|
GO:0009190 |
61 |
0.016
|
|
|
|
protein import into nucleus
|
GO:0006606 |
104 |
0.015
|
|
|
|
cell junction assembly
|
GO:0034329 |
67 |
0.015
|
|
|
|
innate immune response activating signal transduction
|
GO:0002758 |
48 |
0.015
|
|
|
|
osteoblast differentiation
|
GO:0001649 |
92 |
0.015
|
|
|
|
mrna processing
|
GO:0006397 |
133 |
0.015
|
|
|
|
fatty acid catabolic process
|
GO:0009062 |
29 |
0.015
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
264 |
0.015
|
|
|
|
protein targeting
|
GO:0006605 |
187 |
0.015
|
|
|
|
glycosphingolipid metabolic process
|
GO:0006687 |
13 |
0.015
|
|
|
|
regulation of adenylate cyclase activity
|
GO:0045761 |
17 |
0.015
|
|
|
|
regulation of cell shape
|
GO:0008360 |
48 |
0.015
|
|
|
|
signal transduction in response to dna damage
|
GO:0042770 |
57 |
0.015
|
|
|
|
cellular response to ammonium ion
|
GO:0071242 |
4 |
0.015
|
|
|
|
regulation of cell activation
|
GO:0050865 |
125 |
0.014
|
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
209 |
0.014
|
|
|
|
immune response activating cell surface receptor signaling pathway
|
GO:0002429 |
45 |
0.014
|
|
|
|
negative regulation of protein maturation
|
GO:1903318 |
142 |
0.014
|
|
|
|
negative regulation of kinase activity
|
GO:0033673 |
106 |
0.014
|
|
|
|
oxidation reduction process
|
GO:0055114 |
396 |
0.014
|
|
|
|
microtubule organizing center organization
|
GO:0031023 |
62 |
0.014
|
|
|
|
memory
|
GO:0007613 |
3 |
0.014
|
|
|
|
regulation of rho gtpase activity
|
GO:0032319 |
66 |
0.014
|
|
|
|
pattern recognition receptor signaling pathway
|
GO:0002221 |
48 |
0.014
|
|
|
|
positive regulation of axon extension
|
GO:0045773 |
4 |
0.014
|
|
|
|
regulation of sphingomyelin catabolic process
|
GO:2000754 |
1 |
0.014
|
|
|
|
innate immune response
|
GO:0045087 |
178 |
0.014
|
|
|
|
syncytium formation by plasma membrane fusion
|
GO:0000768 |
2 |
0.014
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
155 |
0.014
|
|
|
|
liposaccharide metabolic process
|
GO:1903509 |
27 |
0.013
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.013
|
|
|
|
golgi vesicle fusion to target membrane
|
GO:0048210 |
2 |
0.013
|
|
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
99 |
0.013
|
|
|
|
phospholipid metabolic process
|
GO:0006644 |
99 |
0.013
|
|
|
|
negative regulation of catabolic process
|
GO:0009895 |
104 |
0.013
|
|
|
|
reactive nitrogen species metabolic process
|
GO:2001057 |
3 |
0.013
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.013
|
|
|
|
positive regulation of rho protein signal transduction
|
GO:0035025 |
4 |
0.013
|
|
|
|
response to oxidative stress
|
GO:0006979 |
121 |
0.013
|
|
|
|
establishment of organelle localization
|
GO:0051656 |
59 |
0.013
|
|
|
|
regulation of actin polymerization or depolymerization
|
GO:0008064 |
56 |
0.013
|
|
|
|
rhythmic behavior
|
GO:0007622 |
2 |
0.013
|
|
|
|
endocytosis
|
GO:0006897 |
159 |
0.013
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
156 |
0.013
|
|
|
|
cellular carbohydrate metabolic process
|
GO:0044262 |
84 |
0.013
|
|
|
|
long term synaptic potentiation
|
GO:0060291 |
1 |
0.013
|
|
|
|
taxis
|
GO:0042330 |
157 |
0.013
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.013
|
|
|
|
retina layer formation
|
GO:0010842 |
3 |
0.013
|
|
|
|
membrane raft localization
|
GO:0051665 |
1 |
0.013
|
|
|
|
positive regulation of reactive oxygen species metabolic process
|
GO:2000379 |
24 |
0.012
|
|
|
|
actin polymerization or depolymerization
|
GO:0008154 |
56 |
0.012
|
|
|
|
monosaccharide metabolic process
|
GO:0005996 |
74 |
0.012
|
|
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
108 |
0.012
|
|
|
|
dephosphorylation
|
GO:0016311 |
209 |
0.012
|
|
|
|
protein maturation
|
GO:0051604 |
233 |
0.012
|
|
|
|
ribonucleoside monophosphate catabolic process
|
GO:0009158 |
158 |
0.012
|
|
|
|
ncrna processing
|
GO:0034470 |
83 |
0.012
|
|
|
|
cartilage development involved in endochondral bone morphogenesis
|
GO:0060351 |
2 |
0.012
|
|
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.012
|
|
|
|
cellular response to hypoxia
|
GO:0071456 |
51 |
0.012
|
|
|
|
microtubule polymerization or depolymerization
|
GO:0031109 |
37 |
0.012
|
|
|
|
regulation of phosphatase activity
|
GO:0010921 |
81 |
0.012
|
|
|
|
peptidyl lysine modification
|
GO:0018205 |
144 |
0.012
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
136 |
0.012
|
|
|
|
positive regulation of phospholipid scramblase activity
|
GO:1900163 |
1 |
0.012
|
|
|
|
apoptotic mitochondrial changes
|
GO:0008637 |
57 |
0.012
|
|
|
|
organelle assembly
|
GO:0070925 |
176 |
0.012
|
|
|
|
regulation of blood circulation
|
GO:1903522 |
59 |
0.012
|
|
|
|
positive regulation of sphingomyelin catabolic process
|
GO:2000755 |
1 |
0.012
|
|
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
207 |
0.012
|
|
|
|
negative regulation of cardiac muscle cell proliferation
|
GO:0060044 |
2 |
0.012
|
|
