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Process View

Homo sapiens

10 genes annotated in human

Multi-species View

negative regulation of developmental growth

GO:0048640

Any process that stops, prevents, or reduces the frequency, rate or extent of developmental growth.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "negative regulation of developmental growth"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "negative regulation of developmental growth" (in gray)

Name	Description	Probability	Func Analog Organism
FYN	FYN oncogene related to SRC, FGR, YES	0.898	Fly
CREBBP	CREB binding protein	0.755
AR	androgen receptor	0.562
CTNNB1	catenin (cadherin-associated protein), beta 1, 88kDa	0.362
TSC2	tuberous sclerosis 2	0.353	Fly
FGF1	fibroblast growth factor 1 (acidic)	0.334
SNX9	sorting nexin 9	0.315
TTR	transthyretin	0.305
SRC	v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)	0.290	Fly
STK3	serine/threonine kinase 3	0.207	Mouse
WIPF1	WAS/WASL interacting protein family, member 1	0.206
BMPR1A	bone morphogenetic protein receptor, type IA	0.157
SPTAN1	spectrin, alpha, non-erythrocytic 1 (alpha-fodrin)	0.118
SMAD1	SMAD family member 1	0.104
ATG13	ATG13 autophagy related 13 homolog (S. cerevisiae)	0.103
RASSF1	Ras association (RalGDS/AF-6) domain family member 1	0.092
PSTPIP1	proline-serine-threonine phosphatase interacting protein 1	0.085
VEGFA	vascular endothelial growth factor A	0.070
LUC7L2	LUC7-like 2 (S. cerevisiae)	0.068
NKX2-5	NK2 transcription factor related, locus 5 (Drosophila)	0.068
SLC9A3R1	solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1	0.067
PTN	pleiotrophin	0.067
STK4	serine/threonine kinase 4	0.061	Mouse
MAGI3	membrane associated guanylate kinase, WW and PDZ domain containing 3	0.056
SPRR2A	small proline-rich protein 2A	0.056
MAGI2	membrane associated guanylate kinase, WW and PDZ domain containing 2	0.055
MED28	mediator complex subunit 28	0.053
NCOA6	nuclear receptor coactivator 6	0.052
SCHIP1	schwannomin interacting protein 1	0.049
NCOA2	nuclear receptor coactivator 2	0.048
FSTL1	follistatin-like 1	0.047
ITGB1	integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)	0.047
NXF1	nuclear RNA export factor 1	0.047
FGFR2	fibroblast growth factor receptor 2	0.046	Fly
SIRT1	sirtuin 1	0.044
ERBB3	v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)	0.043
YAP1	Yes-associated protein 1	0.042
SPG21	spastic paraplegia 21 (autosomal recessive, Mast syndrome)	0.041
TSC1	tuberous sclerosis 1	0.041	Fly
YWHAG	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide	0.037
CABLES1	Cdk5 and Abl enzyme substrate 1	0.037
TGFB3	transforming growth factor, beta 3	0.037
PDCD6IP	programmed cell death 6 interacting protein	0.037
BAIAP2	BAI1-associated protein 2	0.037
MLL	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila)	0.036
PAG1	phosphoprotein associated with glycosphingolipid microdomains 1	0.036
CLASP1	cytoplasmic linker associated protein 1	0.036
LYN	v-yes-1 Yamaguchi sarcoma viral related oncogene homolog	0.032
SPG20	spastic paraplegia 20 (Troyer syndrome)	0.031
GAS7	growth arrest-specific 7	0.030
YWHAB	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide	0.029
RASSF3	Ras association (RalGDS/AF-6) domain family member 3	0.029
WAS	Wiskott-Aldrich syndrome (eczema-thrombocytopenia)	0.027	Fly
ERBB2	v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)	0.022
PTEN	phosphatase and tensin homolog	0.021	Mouse Fly
KAT2B	K(lysine) acetyltransferase 2B	0.020
COL4A3BP	collagen, type IV, alpha 3 (Goodpasture antigen) binding protein	0.020
GRB2	growth factor receptor-bound protein 2	0.020
GRB7	growth factor receptor-bound protein 7	0.019
BTK	Bruton agammaglobulinemia tyrosine kinase	0.019
MOBKL1B	MOB1, Mps One Binder kinase activator-like 1B (yeast)	0.019
SUV39H1	suppressor of variegation 3-9 homolog 1 (Drosophila)	0.019
CYFIP2	cytoplasmic FMR1 interacting protein 2	0.019
SATB2	SATB homeobox 2	0.019
BMP7	bone morphogenetic protein 7	0.019
ITGB2	integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)	0.018
BTRC	beta-transducin repeat containing	0.018
PXN	paxillin	0.017
RASSF5	Ras association (RalGDS/AF-6) domain family member 5	0.017
KDR	kinase insert domain receptor (a type III receptor tyrosine kinase)	0.017
SMAD2	SMAD family member 2	0.017
FASLG	Fas ligand (TNF superfamily, member 6)	0.016
PTK2	PTK2 protein tyrosine kinase 2	0.016	Mouse Fly
PTPRC	protein tyrosine phosphatase, receptor type, C	0.016
INO80B	INO80 complex subunit B	0.016
RNF11	ring finger protein 11	0.015
RB1CC1	RB1-inducible coiled-coil 1	0.015
NCOA1	nuclear receptor coactivator 1	0.015
FHL2	four and a half LIM domains 2	0.015
SMAD7	SMAD family member 7	0.015	Fly
CDH1	cadherin 1, type 1, E-cadherin (epithelial)	0.015
PRKCZ	protein kinase C, zeta	0.015
FOXO1	forkhead box O1	0.015	Worm Fly
CTTN	cortactin	0.014
LCK	lymphocyte-specific protein tyrosine kinase	0.014	Fly
DCC	deleted in colorectal carcinoma	0.014
PIAS4	protein inhibitor of activated STAT, 4	0.014
TNKS	tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase	0.014
CREB1	cAMP responsive element binding protein 1	0.014
AXIN1	axin 1	0.014
FGF10	fibroblast growth factor 10	0.013
CDC42	cell division cycle 42 (GTP binding protein, 25kDa)	0.013
WWOX	WW domain containing oxidoreductase	0.013
CRK	v-crk sarcoma virus CT10 oncogene homolog (avian)	0.013
ENG	endoglin	0.013
RB1	retinoblastoma 1	0.013
APPL1	adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1	0.012
KRT5	keratin 5	0.012
NCK1	NCK adaptor protein 1	0.012
FAT1	FAT tumor suppressor homolog 1 (Drosophila)	0.012
BMI1	BMI1 polycomb ring finger oncogene	0.012
CDK5R1	cyclin-dependent kinase 5, regulatory subunit 1 (p35)	0.012	Mouse
MAPK6	mitogen-activated protein kinase 6	0.012
FZD1	frizzled homolog 1 (Drosophila)	0.012
PTPN14	protein tyrosine phosphatase, non-receptor type 14	0.012
BCAR1	breast cancer anti-estrogen resistance 1	0.012
RAB11FIP1	RAB11 family interacting protein 1 (class I)	0.012
HTT	huntingtin	0.012
RABGAP1	RAB GTPase activating protein 1	0.011
SMAD6	SMAD family member 6	0.011	Fly
HIF1A	hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	0.011
HCLS1	hematopoietic cell-specific Lyn substrate 1	0.011
DYRK1A	dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A	0.011
ARHGEF40	Rho guanine nucleotide exchange factor (GEF) 40	0.011
SH3RF1	SH3 domain containing ring finger 1	0.011
IKBKB	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta	0.011
IRF3	interferon regulatory factor 3	0.010
SAV1	salvador homolog 1 (Drosophila)	0.010	Mouse