Homo sapiens

29 known processes

APOL3

apolipoprotein L, 3

(Aliases: CG121,APOLIII)

APOL3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
positive regulation of i kappab kinase nf kappab signaling GO:0043123 132 0.445
cytokine production GO:0001816 247 0.401
positive regulation of cytokine production GO:0001819 167 0.263
positive regulation of immune system process GO:0002684 283 0.227
regulation of cytokine production GO:0001817 232 0.187
immune response GO:0006955 307 0.166
Human
detection of muramyl dipeptide GO:0032498 1 0.154
defense response GO:0006952 315 0.150
Human
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.131
chloride transport GO:0006821 41 0.111
Human
negative regulation of protein activation cascade GO:2000258 7 0.106
regulation of immune response GO:0050776 201 0.106
activation of immune response GO:0002253 114 0.105
positive regulation of immune response GO:0050778 159 0.102
organophosphate catabolic process GO:0046434 430 0.095
inorganic anion transmembrane transport GO:0098661 47 0.088
Human
t cell activation GO:0042110 99 0.081
innate immune response GO:0045087 178 0.081
Human
regulation of leukocyte activation GO:0002694 115 0.077
purine nucleoside triphosphate catabolic process GO:0009146 392 0.074
negative regulation of multicellular organismal process GO:0051241 317 0.073
leukocyte activation GO:0045321 164 0.073
regulation of immune effector process GO:0002697 91 0.068
purine nucleotide catabolic process GO:0006195 405 0.067
cytoplasmic transport GO:0016482 379 0.067
positive regulation of transport GO:0051050 336 0.065
anion transport GO:0006820 161 0.064
Human
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.063
positive regulation of developmental process GO:0051094 314 0.063
response to other organism GO:0051707 261 0.063
regulation of transferase activity GO:0051338 355 0.062
purine ribonucleotide catabolic process GO:0009154 404 0.062
regulation of mononuclear cell proliferation GO:0032944 65 0.061
immune system development GO:0002520 195 0.060
anion transmembrane transport GO:0098656 76 0.060
Human
ribonucleoside catabolic process GO:0042454 406 0.060
regulation of lymphocyte activation GO:0051249 103 0.060
regulation of protein transport GO:0051223 213 0.059
inorganic ion transmembrane transport GO:0098660 231 0.057
Human
regulation of cell activation GO:0050865 125 0.057
guanosine containing compound catabolic process GO:1901069 239 0.057
cation transport GO:0006812 331 0.056
nucleoside triphosphate catabolic process GO:0009143 394 0.056
positive regulation of cell activation GO:0050867 81 0.055
t cell proliferation GO:0042098 45 0.055
ion transmembrane transport GO:0034220 338 0.053
Human
multi organism cellular process GO:0044764 156 0.053
ribonucleoside triphosphate catabolic process GO:0009203 391 0.052
regulation of t cell activation GO:0050863 77 0.051
lipid metabolic process GO:0006629 381 0.051
positive regulation of protein transport GO:0051222 135 0.051
leukocyte differentiation GO:0002521 98 0.050
purine containing compound catabolic process GO:0072523 411 0.050
gtp metabolic process GO:0046039 239 0.049
protein modification by small protein conjugation GO:0032446 342 0.049
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.048
positive regulation of lymphocyte activation GO:0051251 73 0.048
regulation of cellular ketone metabolic process GO:0010565 50 0.047
immune effector process GO:0002252 159 0.046
negative regulation of immune system process GO:0002683 136 0.046
gtp catabolic process GO:0006184 237 0.044
nucleoside triphosphate metabolic process GO:0009141 422 0.044
regulation of leukocyte differentiation GO:1902105 61 0.042
ribonucleotide catabolic process GO:0009261 405 0.042
regulation of cellular amino acid metabolic process GO:0006521 6 0.041
response to interferon gamma GO:0034341 39 0.041
positive regulation of t cell activation GO:0050870 54 0.041
regulation of t cell proliferation GO:0042129 42 0.041
regulation of cell differentiation GO:0045595 393 0.040
response to external biotic stimulus GO:0043207 261 0.040
mapk cascade GO:0000165 288 0.040
regulation of cell migration GO:0030334 289 0.040
i kappab kinase nf kappab signaling GO:0007249 166 0.040
purine ribonucleoside catabolic process GO:0046130 398 0.039
regulation of intracellular transport GO:0032386 195 0.039
cell killing GO:0001906 34 0.039
Human
nucleoside phosphate catabolic process GO:1901292 412 0.038
nucleoside catabolic process GO:0009164 408 0.038
cell activation GO:0001775 213 0.038
cellular response to cytokine stimulus GO:0071345 181 0.037
purine nucleoside catabolic process GO:0006152 398 0.036
defense response to other organism GO:0098542 129 0.036
positive regulation of leukocyte proliferation GO:0070665 48 0.036
biological adhesion GO:0022610 331 0.036
cellular amine metabolic process GO:0044106 41 0.036
regulation of protein secretion GO:0050708 86 0.036
positive regulation of leukocyte activation GO:0002696 80 0.036
positive regulation of cell proliferation GO:0008284 301 0.035
purine ribonucleoside metabolic process GO:0046128 437 0.035
multicellular organismal aging GO:0010259 3 0.035
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.035
protein secretion GO:0009306 98 0.034
interspecies interaction between organisms GO:0044419 156 0.034
immune response activating signal transduction GO:0002757 90 0.034
guanosine containing compound metabolic process GO:1901068 244 0.033
cellular lipid metabolic process GO:0044255 303 0.033
nucleotide catabolic process GO:0009166 408 0.032
inorganic anion transport GO:0015698 60 0.032
Human
cellular response to interferon gamma GO:0071346 24 0.032
negative regulation of catalytic activity GO:0043086 335 0.032
post embryonic development GO:0009791 2 0.032
regulation of anatomical structure morphogenesis GO:0022603 286 0.032
protein maturation GO:0051604 233 0.032
purine nucleoside triphosphate metabolic process GO:0009144 412 0.031
hematopoietic or lymphoid organ development GO:0048534 186 0.031
mononuclear cell proliferation GO:0032943 71 0.031
regulation of cellular amine metabolic process GO:0033238 11 0.031
regulation of dna metabolic process GO:0051052 153 0.031
regulation of cd8 positive alpha beta t cell proliferation GO:2000564 1 0.030
apoptotic signaling pathway GO:0097190 268 0.030
pattern recognition receptor signaling pathway GO:0002221 48 0.030
oogenesis GO:0048477 2 0.030
ribonucleoside triphosphate metabolic process GO:0009199 412 0.029
positive regulation of mononuclear cell proliferation GO:0032946 47 0.029
regulation of innate immune response GO:0045088 97 0.029
regulation of establishment of protein localization GO:0070201 242 0.029
negative regulation of protein maturation GO:1903318 142 0.028
regulation of response to external stimulus GO:0032101 222 0.028
regulation of mapk cascade GO:0043408 262 0.028
signal transduction by phosphorylation GO:0023014 297 0.028
response to biotic stimulus GO:0009607 276 0.028
regulation of protein maturation GO:1903317 150 0.027
cellular macromolecule catabolic process GO:0044265 380 0.027
metal ion transport GO:0030001 272 0.027
cell fate determination GO:0001709 3 0.026
positive regulation of cytoplasmic transport GO:1903651 82 0.026
glycosyl compound catabolic process GO:1901658 413 0.026
positive regulation of cell differentiation GO:0045597 211 0.026
negative regulation of transport GO:0051051 176 0.026
positive regulation of innate immune response GO:0045089 79 0.026
protein targeting GO:0006605 187 0.026
regulation of cell motility GO:2000145 299 0.026
regulation of cellular component movement GO:0051270 334 0.026
ras protein signal transduction GO:0007265 73 0.025
positive regulation of cellular amine metabolic process GO:0033240 7 0.025
secretion GO:0046903 254 0.025
activation of innate immune response GO:0002218 55 0.025
regulation of interferon gamma production GO:0032649 36 0.025
angiogenesis GO:0001525 147 0.025
leukocyte proliferation GO:0070661 74 0.025
negative regulation of cell cycle GO:0045786 193 0.025
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.025
positive regulation of leukocyte differentiation GO:1902107 37 0.024
innate immune response activating signal transduction GO:0002758 48 0.024
chloride transmembrane transport GO:1902476 38 0.024
Human
ion homeostasis GO:0050801 230 0.024
negative regulation of immune response GO:0050777 40 0.024
cytokine secretion GO:0050663 64 0.024
cellular homeostasis GO:0019725 196 0.024
response to tumor necrosis factor GO:0034612 76 0.024
cellular protein catabolic process GO:0044257 261 0.024
cellular amino acid metabolic process GO:0006520 116 0.024
phospholipid metabolic process GO:0006644 99 0.023
regulation of vasculature development GO:1901342 97 0.023
negative regulation of intracellular signal transduction GO:1902532 183 0.023
immune response regulating signaling pathway GO:0002764 97 0.023
negative regulation of protein metabolic process GO:0051248 391 0.023
blood vessel development GO:0001568 172 0.023
system process GO:0003008 349 0.022
positive regulation of secretion GO:0051047 116 0.022
immune response activating cell surface receptor signaling pathway GO:0002429 45 0.022
regulation of protein localization GO:0032880 296 0.022
negative regulation of cytokine production GO:0001818 82 0.021
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.021
positive regulation of mapk cascade GO:0043410 190 0.021
regulation of secretion by cell GO:1903530 177 0.021
jnk cascade GO:0007254 80 0.021
lymphocyte activation GO:0046649 133 0.021
regulation of protein processing GO:0070613 150 0.021
regulation of lymphocyte proliferation GO:0050670 64 0.021
negative regulation of protein processing GO:0010955 142 0.021
single organism cellular localization GO:1902580 332 0.021
regulation of secretion GO:0051046 194 0.021
regulation of leukocyte proliferation GO:0070663 67 0.021
protein localization to organelle GO:0033365 280 0.021
positive regulation of phosphorylation GO:0042327 394 0.020
regulation of locomotion GO:0040012 329 0.020
cellular macromolecular complex assembly GO:0034622 324 0.020
amine metabolic process GO:0009308 44 0.020
positive regulation of lymphocyte proliferation GO:0050671 46 0.020
immune response regulating cell surface receptor signaling pathway GO:0002768 51 0.020
regulation of mhc class ii biosynthetic process GO:0045346 4 0.020
protein catabolic process GO:0030163 325 0.020
regulation of cytokine biosynthetic process GO:0042035 35 0.020
glycosylation GO:0070085 71 0.019
response to oxygen containing compound GO:1901700 369 0.019
regulation of interleukin 10 secretion GO:2001179 4 0.019
regulation of apoptotic signaling pathway GO:2001233 175 0.019
determination of adult lifespan GO:0008340 2 0.019
compound eye development GO:0048749 1 0.019
secretion by cell GO:0032940 226 0.019
circadian behavior GO:0048512 2 0.019
regulation of behavior GO:0050795 82 0.019
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.019
response to nitrogen compound GO:1901698 184 0.018
lymphocyte proliferation GO:0046651 70 0.018
hemopoiesis GO:0030097 180 0.018
transmembrane transport GO:0055085 399 0.018
Human
regulation of kinase activity GO:0043549 314 0.018
protein processing GO:0016485 226 0.018
vesicle mediated transport GO:0016192 371 0.018
negative regulation of cellular protein metabolic process GO:0032269 353 0.018
positive regulation of transferase activity GO:0051347 227 0.018
positive regulation of protein localization to nucleus GO:1900182 48 0.018
positive regulation of secretion by cell GO:1903532 108 0.018
female gamete generation GO:0007292 2 0.017
cellular cation homeostasis GO:0030003 163 0.017
regulation of proteolysis GO:0030162 293 0.017
cytokine mediated signaling pathway GO:0019221 109 0.017
cellular protein complex assembly GO:0043623 188 0.017
intracellular protein transport GO:0006886 270 0.017
negative regulation of blood vessel morphogenesis GO:2000181 41 0.017
positive regulation of catabolic process GO:0009896 310 0.017
maintenance of location GO:0051235 112 0.017
response to molecule of bacterial origin GO:0002237 82 0.017
positive regulation of protein secretion GO:0050714 60 0.017
regulation of cytoplasmic transport GO:1903649 149 0.017
negative regulation of developmental process GO:0051093 247 0.017
divalent inorganic cation transport GO:0072511 158 0.017
regulation of angiogenesis GO:0045765 92 0.016
cellular response to growth factor stimulus GO:0071363 197 0.016
negative regulation of intracellular transport GO:0032387 60 0.016
cellular ketone metabolic process GO:0042180 80 0.016
blood vessel morphogenesis GO:0048514 162 0.016
peptide metabolic process GO:0006518 51 0.016
cation homeostasis GO:0055080 189 0.016
spermatid differentiation GO:0048515 4 0.016
ubiquitin dependent protein catabolic process GO:0006511 206 0.016
negative regulation of cell motility GO:2000146 104 0.016
cell cycle phase transition GO:0044770 173 0.016
positive regulation of response to external stimulus GO:0032103 88 0.016
regulation of purine nucleotide metabolic process GO:1900542 264 0.016
syncytium formation by plasma membrane fusion GO:0000768 2 0.016
cell morphogenesis GO:0000902 296 0.015
calcium ion homeostasis GO:0055074 122 0.015
myoblast fusion GO:0007520 1 0.015
positive regulation of intracellular transport GO:0032388 104 0.015
cellular component morphogenesis GO:0032989 314 0.015
negative regulation of proteolysis GO:0045861 132 0.015
positive regulation of cell death GO:0010942 263 0.015
memory GO:0007613 3 0.015
negative regulation of vasculature development GO:1901343 43 0.015
negative regulation of cellular component organization GO:0051129 235 0.015
positive regulation of nucleocytoplasmic transport GO:0046824 54 0.015
divalent inorganic cation homeostasis GO:0072507 136 0.015
regulation of extrinsic apoptotic signaling pathway GO:2001236 85 0.015
regulation of peptidase activity GO:0052547 180 0.015
negative regulation of cell differentiation GO:0045596 171 0.014
protein ubiquitination GO:0016567 314 0.014
positive regulation of erk1 and erk2 cascade GO:0070374 75 0.014
defense response to bacterium GO:0042742 63 0.014
circulatory system development GO:0072359 262 0.014
negative regulation of phosphate metabolic process GO:0045936 267 0.014
protein localization to nucleus GO:0034504 136 0.014
regulation of cell cycle GO:0051726 393 0.014
negative regulation of protein modification process GO:0031400 200 0.014
regulation of protein localization to nucleus GO:1900180 85 0.014
cell adhesion GO:0007155 325 0.014
negative regulation of cytolysis GO:0045918 3 0.014
positive regulation of apoptotic process GO:0043065 246 0.014
regulation of response to wounding GO:1903034 101 0.014
extrinsic apoptotic signaling pathway GO:0097191 119 0.014
mitotic cell cycle phase transition GO:0044772 162 0.014
modification dependent protein catabolic process GO:0019941 209 0.014
negative regulation of cell proliferation GO:0008285 228 0.013
negative regulation of phosphorus metabolic process GO:0010563 267 0.013
positive regulation of hydrolase activity GO:0051345 331 0.013
cellular ion homeostasis GO:0006873 168 0.013
anatomical structure homeostasis GO:0060249 100 0.013
positive regulation of interferon alpha production GO:0032727 11 0.013
regulation of intracellular protein transport GO:0033157 123 0.013
adaptive immune response GO:0002250 49 0.013
divalent metal ion transport GO:0070838 152 0.013
response to abiotic stimulus GO:0009628 336 0.013
intracellular receptor signaling pathway GO:0030522 104 0.013
anatomical structure formation involved in morphogenesis GO:0048646 284 0.013
negative regulation of synaptic transmission GO:0050805 2 0.013
protein oligomerization GO:0051259 173 0.013
posttranscriptional regulation of gene expression GO:0010608 213 0.013
cellular response to lipid GO:0071396 127 0.013
positive regulation of programmed cell death GO:0043068 249 0.013
regulation of tumor necrosis factor production GO:0032680 43 0.013
detection of chemical stimulus GO:0009593 55 0.013
positive regulation of cellular component organization GO:0051130 376 0.013
positive regulation of kinase activity GO:0033674 204 0.013
regulation of cell cell adhesion GO:0022407 57 0.013
multicellular organismal homeostasis GO:0048871 67 0.013
regulation of defense response GO:0031347 154 0.013
positive regulation of cellular component biogenesis GO:0044089 158 0.013
cellular chemical homeostasis GO:0055082 180 0.013
modification dependent macromolecule catabolic process GO:0043632 212 0.013
regulation of syncytium formation by plasma membrane fusion GO:0060142 2 0.013
response to organonitrogen compound GO:0010243 156 0.013
hemostasis GO:0007599 76 0.012
regulation of cellular response to stress GO:0080135 244 0.012
negative regulation of angiogenesis GO:0016525 39 0.012
regulation of cell adhesion GO:0030155 166 0.012
negative regulation of complement activation GO:0045916 7 0.012
positive regulation of cellular catabolic process GO:0031331 284 0.012
negative regulation of protein transport GO:0051224 75 0.012
release of cytoplasmic sequestered nf kappab GO:0008588 4 0.012
cell cycle arrest GO:0007050 71 0.012
rhythmic behavior GO:0007622 2 0.012
cardiovascular system development GO:0072358 262 0.012
mitotic cell cycle process GO:1903047 286 0.012
stress activated mapk cascade GO:0051403 93 0.012
nervous system development GO:0007399 293 0.012
regulation of cytoskeleton organization GO:0051493 177 0.012
single organism nuclear import GO:1902593 104 0.012
response to virus GO:0009615 126 0.012
positive regulation of nucleoside metabolic process GO:0045979 186 0.012
regulation of regulatory t cell differentiation GO:0045589 4 0.012
defense response to virus GO:0051607 71 0.012
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.012
chemical homeostasis GO:0048878 306 0.012
regulation of erk1 and erk2 cascade GO:0070372 99 0.012
protein modification by small protein removal GO:0070646 92 0.012
t cell mediated immunity GO:0002456 25 0.012
cell development GO:0048468 328 0.012
regulation of metal ion transport GO:0010959 120 0.012
developmental programmed cell death GO:0010623 3 0.012
regulation of cellular component biogenesis GO:0044087 281 0.012
regulation of complement activation lectin pathway GO:0001868 2 0.012
purine nucleotide biosynthetic process GO:0006164 84 0.012
protein import GO:0017038 130 0.011
nucleocytoplasmic transport GO:0006913 176 0.011
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.011
nuclear import GO:0051170 106 0.011
regulation of protein catabolic process GO:0042176 155 0.011
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.011
vasculature development GO:0001944 181 0.011
regulation of nucleotide metabolic process GO:0006140 269 0.011
single organism membrane organization GO:0044802 268 0.011
regulation of protein kinase activity GO:0045859 289 0.011
nuclear transport GO:0051169 179 0.011
cytokine biosynthetic process GO:0042089 37 0.011
positive regulation of type i interferon production GO:0032481 20 0.011
regulation of endopeptidase activity GO:0052548 170 0.011
response to cytokine GO:0034097 232 0.011
establishment of protein localization to organelle GO:0072594 172 0.011
negative regulation of complement activation lectin pathway GO:0001869 2 0.011
spermatid development GO:0007286 4 0.011
macromolecule glycosylation GO:0043413 63 0.011
response to lipid GO:0033993 206 0.011
membrane organization GO:0061024 292 0.011
response to growth factor GO:0070848 205 0.011
positive regulation of activated t cell proliferation GO:0042104 11 0.011
single organism carbohydrate metabolic process GO:0044723 193 0.011
rho protein signal transduction GO:0007266 26 0.011
negative regulation of nucleocytoplasmic transport GO:0046823 37 0.011
cellular response to oxygen containing compound GO:1901701 276 0.011
membrane hyperpolarization GO:0060081 1 0.011
negative regulation of apoptotic process GO:0043066 316 0.011
t cell differentiation in thymus GO:0033077 4 0.011
cytolysis GO:0019835 8 0.010
Human
regulation of multi organism process GO:0043900 157 0.010
regulation of ras protein signal transduction GO:0046578 155 0.010
positive regulation of behavior GO:0048520 60 0.010
cellular divalent inorganic cation homeostasis GO:0072503 128 0.010
protein autoprocessing GO:0016540 4 0.010
viral process GO:0016032 146 0.010
cellular response to dna damage stimulus GO:0006974 379 0.010
small gtpase mediated signal transduction GO:0007264 78 0.010
tissue homeostasis GO:0001894 63 0.010
response to wounding GO:0009611 168 0.010
metal ion homeostasis GO:0055065 169 0.010
protein targeting to nucleus GO:0044744 104 0.010
negative regulation of protein phosphorylation GO:0001933 140 0.010
erk1 and erk2 cascade GO:0070371 104 0.010
negative regulation of phosphorylation GO:0042326 174 0.010
small molecule catabolic process GO:0044282 92 0.010
negative regulation of t cell activation GO:0050868 18 0.010
regulation of type i interferon production GO:0032479 26 0.010
regulation of ras gtpase activity GO:0032318 128 0.010
neurological system process GO:0050877 163 0.010
positive regulation of interferon gamma production GO:0032729 26 0.010

APOL3 disease predictions

Disease DO term ID Size Probability Func Analog Org
urinary system disease DOID:18 40 0.031
Human
kidney disease DOID:557 36 0.028
Human
disease of cellular proliferation DOID:14566 174 0.026
sensory system disease DOID:0050155 203 0.017
nervous system disease DOID:863 431 0.017
cancer DOID:162 167 0.016
organ system cancer DOID:0050686 164 0.016
musculoskeletal system disease DOID:17 223 0.013
eye and adnexa disease DOID:1492 150 0.013
eye disease DOID:5614 149 0.012