Homo sapiens

0 known processes

CTSA

cathepsin A

(Aliases: PPGB,PPCA,GLB2,NGBE,GSL)

CTSA biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
vacuole organization GO:0007033 44 0.976
negative regulation of blood vessel remodeling GO:0060313 1 0.968
single organism carbohydrate catabolic process GO:0044724 33 0.797
epithelium development GO:0060429 227 0.775
signal transduction by phosphorylation GO:0023014 297 0.703
anatomical structure homeostasis GO:0060249 100 0.686
regulation of blood vessel remodeling GO:0060312 2 0.684
cellular amide metabolic process GO:0043603 69 0.576
regulation of systemic arterial blood pressure by circulatory renin angiotensin GO:0001991 4 0.498
carbohydrate catabolic process GO:0016052 36 0.497
regulation of elastin catabolic process GO:0060310 1 0.465
urogenital system development GO:0001655 65 0.451
negative regulation of elastin catabolic process GO:0060311 1 0.420
negative regulation of collagen catabolic process GO:0010711 1 0.414
granzyme mediated apoptotic signaling pathway GO:0008626 4 0.413
regulation of angiotensin metabolic process GO:0060177 3 0.410
multicellular organismal homeostasis GO:0048871 67 0.409
epithelial cell differentiation GO:0030855 141 0.394
carbohydrate metabolic process GO:0005975 207 0.356
regulation of angiotensin levels in blood GO:0002002 3 0.334
multicellular organismal aging GO:0010259 3 0.328
lipid catabolic process GO:0016042 84 0.327
basic amino acid transport GO:0015802 3 0.326
determination of adult lifespan GO:0008340 2 0.290
sphingolipid metabolic process GO:0006665 38 0.288
neurological system process GO:0050877 163 0.273
negative regulation of multicellular organismal metabolic process GO:0044252 3 0.267
transmembrane transport GO:0055085 399 0.263
camera type eye development GO:0043010 25 0.236
system process GO:0003008 349 0.220
mapk cascade GO:0000165 288 0.199
ganglioside catabolic process GO:0006689 3 0.197
autophagic vacuole assembly GO:0000045 19 0.194
single organism carbohydrate metabolic process GO:0044723 193 0.189
post embryonic development GO:0009791 2 0.183
regulation of mapk cascade GO:0043408 262 0.178
chemical homeostasis GO:0048878 306 0.176
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 43 0.171
regulation of systemic arterial blood pressure by hormone GO:0001990 12 0.171
membrane lipid metabolic process GO:0006643 53 0.170
tissue homeostasis GO:0001894 63 0.160
protein processing GO:0016485 226 0.155
elastin catabolic process GO:0060309 1 0.146
kidney development GO:0001822 53 0.140
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.135
neuromuscular process GO:0050905 15 0.134
cellular component morphogenesis GO:0032989 314 0.131
retina development in camera type eye GO:0060041 15 0.129
alcohol metabolic process GO:0006066 114 0.124
cellular amine metabolic process GO:0044106 41 0.118
organic hydroxy compound metabolic process GO:1901615 147 0.112
locomotory behavior GO:0007626 1 0.112
cellular macromolecule catabolic process GO:0044265 380 0.111
cellular ion homeostasis GO:0006873 168 0.106
eye development GO:0001654 42 0.106
antigen processing and presentation GO:0019882 33 0.102
microtubule based process GO:0007017 210 0.097
ion homeostasis GO:0050801 230 0.091
protein maturation GO:0051604 233 0.088
renal system development GO:0072001 63 0.087
cellular lipid metabolic process GO:0044255 303 0.084
cellular lipid catabolic process GO:0044242 65 0.082
circulatory system development GO:0072359 262 0.081
necrotic cell death GO:0070265 21 0.080
endocrine process GO:0050886 25 0.080
chemical homeostasis within a tissue GO:0048875 3 0.079
regulation of exocytosis GO:0017157 46 0.078
regulation of lipid metabolic process GO:0019216 96 0.078
membrane protein proteolysis GO:0033619 38 0.077
cellular response to oxidative stress GO:0034599 85 0.076
protein localization to organelle GO:0033365 280 0.073
peripheral nervous system development GO:0007422 2 0.073
organelle assembly GO:0070925 176 0.073
lipid metabolic process GO:0006629 381 0.073
antigen processing and presentation of peptide antigen GO:0048002 18 0.072
nervous system development GO:0007399 293 0.072
liposaccharide metabolic process GO:1903509 27 0.072
positive regulation of natural killer cell mediated immunity GO:0002717 12 0.069
oxidation reduction process GO:0055114 396 0.066
blood circulation GO:0008015 113 0.063
tissue regeneration GO:0042246 3 0.062
macroautophagy GO:0016236 39 0.061
exocytosis GO:0006887 71 0.061
lysosome organization GO:0007040 24 0.060
hair cell differentiation GO:0035315 2 0.060
regulation of osteoclast development GO:2001204 1 0.059
cellular chemical homeostasis GO:0055082 180 0.057
inorganic ion transmembrane transport GO:0098660 231 0.056
regulation of peptidase activity GO:0052547 180 0.056
vesicle mediated transport GO:0016192 371 0.054
negative regulation of cell death GO:0060548 345 0.054
ph reduction GO:0045851 11 0.052
glycolipid metabolic process GO:0006664 27 0.051
response to oxygen containing compound GO:1901700 369 0.050
maintenance of location in cell GO:0051651 62 0.049
hexose catabolic process GO:0019320 7 0.048
proteasomal protein catabolic process GO:0010498 176 0.048
anatomical structure formation involved in morphogenesis GO:0048646 284 0.048
positive regulation of natural killer cell activation GO:0032816 8 0.048
oligosaccharide metabolic process GO:0009311 13 0.048
negative regulation of cellular protein metabolic process GO:0032269 353 0.047
cell development GO:0048468 328 0.047
female gamete generation GO:0007292 2 0.047
response to bacterium GO:0009617 144 0.047
regulation of collagen catabolic process GO:0010710 3 0.047
rhythmic behavior GO:0007622 2 0.045
modification dependent macromolecule catabolic process GO:0043632 212 0.044
positive regulation of mapk cascade GO:0043410 190 0.044
central nervous system development GO:0007417 123 0.044
lipid localization GO:0010876 106 0.043
Worm
peptide hormone processing GO:0016486 9 0.042
multicellular organismal metabolic process GO:0044236 34 0.041
cytoplasmic transport GO:0016482 379 0.041
response to hormone GO:0009725 175 0.041
muscle structure development GO:0061061 98 0.040
antigen processing and presentation of exogenous peptide antigen GO:0002478 4 0.040
regulation of cellular amino acid metabolic process GO:0006521 6 0.039
single organism membrane organization GO:0044802 268 0.038
protein catabolic process GO:0030163 325 0.038
positive regulation of necrotic cell death GO:0010940 4 0.037
negative regulation of programmed cell death GO:0043069 321 0.037
negative regulation of collagen metabolic process GO:0010713 3 0.036
circulatory system process GO:0003013 113 0.036
positive regulation of developmental process GO:0051094 314 0.036
sensory perception of chemical stimulus GO:0007606 38 0.036
cell morphogenesis GO:0000902 296 0.036
growth GO:0040007 202 0.036
cellular cation homeostasis GO:0030003 163 0.035
cation transport GO:0006812 331 0.035
regulation of wnt signaling pathway GO:0030111 123 0.035
receptor mediated endocytosis GO:0006898 84 0.035
blastocyst development GO:0001824 3 0.034
gland development GO:0048732 48 0.034
cellular protein catabolic process GO:0044257 261 0.034
sensory perception of bitter taste GO:0050913 28 0.033
peptide metabolic process GO:0006518 51 0.032
amine metabolic process GO:0009308 44 0.032
response to oxidative stress GO:0006979 121 0.032
negative regulation of multicellular organismal process GO:0051241 317 0.031
natural killer cell activation involved in immune response GO:0002323 2 0.031
regulation of vesicle mediated transport GO:0060627 130 0.030
positive regulation of cell activation GO:0050867 81 0.030
cellular response to reactive oxygen species GO:0034614 50 0.030
defense response GO:0006952 315 0.030
hexose metabolic process GO:0019318 55 0.030
response to alcohol GO:0097305 64 0.030
skin development GO:0043588 76 0.029
negative regulation of catalytic activity GO:0043086 335 0.029
calcium ion transmembrane transport GO:0070588 76 0.028
hormone metabolic process GO:0042445 61 0.028
positive regulation of exocytosis GO:0045921 35 0.028
regulation of cellular response to stress GO:0080135 244 0.028
regulation of oxidative stress induced cell death GO:1903201 24 0.028
regulation of hormone levels GO:0010817 125 0.028
metal ion transport GO:0030001 272 0.028
sensory organ development GO:0007423 52 0.028
galactose metabolic process GO:0006012 4 0.028
hindbrain development GO:0030902 3 0.027
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.027
sensory perception of taste GO:0050909 36 0.027
negative regulation of protein phosphorylation GO:0001933 140 0.027
vacuolar transport GO:0007034 34 0.027
secretion by cell GO:0032940 226 0.027
glycosphingolipid metabolic process GO:0006687 13 0.026
monovalent inorganic cation transport GO:0015672 128 0.026
reproductive process GO:0022414 106 0.026
regulation of protein maturation GO:1903317 150 0.026
regulation of protein stability GO:0031647 87 0.026
cellular amino acid metabolic process GO:0006520 116 0.026
apoptotic signaling pathway GO:0097190 268 0.026
response to external biotic stimulus GO:0043207 261 0.026
striated muscle contraction GO:0006941 52 0.026
positive regulation of cell proliferation GO:0008284 301 0.026
negative regulation of intracellular signal transduction GO:1902532 183 0.025
reactive nitrogen species metabolic process GO:2001057 3 0.025
response to biotic stimulus GO:0009607 276 0.025
regulation of intracellular transport GO:0032386 195 0.025
antigen processing and presentation of peptide antigen via mhc class ii GO:0002495 11 0.025
neuron differentiation GO:0030182 138 0.025
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.025
monosaccharide metabolic process GO:0005996 74 0.024
response to reactive oxygen species GO:0000302 61 0.024
regeneration GO:0031099 4 0.024
muscle contraction GO:0006936 73 0.024
negative regulation of catabolic process GO:0009895 104 0.024
cation transmembrane transport GO:0098655 238 0.024
generation of precursor metabolites and energy GO:0006091 68 0.024
prostate gland development GO:0030850 3 0.023
protein stabilization GO:0050821 64 0.023
peptidyl lysine modification GO:0018205 144 0.023
regulation of ossification GO:0030278 58 0.023
small molecule biosynthetic process GO:0044283 157 0.023
positive regulation of secretion GO:0051047 116 0.023
surfactant homeostasis GO:0043129 3 0.023
neuron projection extension GO:1990138 14 0.023
positive regulation of cellular amine metabolic process GO:0033240 7 0.023
epithelial cell proliferation GO:0050673 128 0.022
negative regulation of protein modification process GO:0031400 200 0.022
cation homeostasis GO:0055080 189 0.022
neuronal action potential GO:0019228 9 0.022
response to organonitrogen compound GO:0010243 156 0.022
amino sugar catabolic process GO:0046348 3 0.022
cell growth GO:0016049 160 0.022
wnt signaling pathway GO:0016055 156 0.021
regulation of kinase activity GO:0043549 314 0.021
response to axon injury GO:0048678 1 0.021
response to starvation GO:0042594 59 0.021
negative regulation of kinase activity GO:0033673 106 0.021
reactive oxygen species biosynthetic process GO:1903409 4 0.021
skeletal system development GO:0001501 79 0.021
regulation of homeostatic process GO:0032844 121 0.021
cerebellum development GO:0021549 2 0.021
bone resorption GO:0045453 6 0.021
cellular response to nutrient levels GO:0031669 69 0.020
negative regulation of protein metabolic process GO:0051248 391 0.020
cellular response to extracellular stimulus GO:0031668 72 0.020
protein modification by small protein conjugation GO:0032446 342 0.020
lysosomal transport GO:0007041 33 0.020
ossification GO:0001503 121 0.020
muscle cell cellular homeostasis GO:0046716 3 0.020
regulation of epithelial cell proliferation GO:0050678 113 0.019
microtubule based movement GO:0007018 32 0.019
epidermal cell differentiation GO:0009913 45 0.019
embryo development GO:0009790 123 0.019
Worm
pigmentation GO:0043473 22 0.019
diaphragm contraction GO:0002086 1 0.019
regulation of transferase activity GO:0051338 355 0.019
negative regulation of glycoprotein metabolic process GO:1903019 8 0.019
glycoprotein catabolic process GO:0006516 7 0.019
developmental cell growth GO:0048588 18 0.019
embryonic retina morphogenesis in camera type eye GO:0060059 1 0.018
negative regulation of hydrolase activity GO:0051346 182 0.018
negative regulation of apoptotic process GO:0043066 316 0.018
response to fungus GO:0009620 4 0.018
embryonic organ morphogenesis GO:0048562 24 0.018
sulfur compound metabolic process GO:0006790 101 0.018
autophagy GO:0006914 88 0.018
negative regulation of peptidase activity GO:0010466 91 0.018
positive regulation of immune effector process GO:0002699 40 0.018
circadian sleep wake cycle process GO:0022410 2 0.018
aging GO:0007568 66 0.018
response to thyroid hormone GO:0097066 9 0.018
regulation of natural killer cell mediated immunity GO:0002715 16 0.018
regulation of secretion GO:0051046 194 0.018
membrane organization GO:0061024 292 0.017
neurogenesis GO:0022008 169 0.017
positive regulation of epithelial cell proliferation GO:0050679 65 0.017
cell projection organization GO:0030030 252 0.017
oogenesis GO:0048477 2 0.017
carbohydrate derivative biosynthetic process GO:1901137 207 0.017
sensory perception of pain GO:0019233 4 0.017
glycerophospholipid metabolic process GO:0006650 84 0.017
regulation of multicellular organismal metabolic process GO:0044246 17 0.017
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.016
cellular homeostasis GO:0019725 196 0.016
negative regulation of cellular response to oxidative stress GO:1900408 18 0.016
single organism reproductive process GO:0044702 98 0.016
peptide catabolic process GO:0043171 10 0.016
microtubule based transport GO:0010970 21 0.016
natural killer cell mediated cytotoxicity GO:0042267 23 0.016
g protein coupled receptor signaling pathway GO:0007186 207 0.016
neuromuscular process controlling posture GO:0050884 2 0.016
establishment of protein localization to organelle GO:0072594 172 0.016
positive regulation of tissue remodeling GO:0034105 4 0.016
response to nitrogen compound GO:1901698 184 0.016
purine nucleoside monophosphate metabolic process GO:0009126 186 0.016
cellular protein complex assembly GO:0043623 188 0.016
natural killer cell activation GO:0030101 12 0.015
sequestering of metal ion GO:0051238 24 0.015
negative regulation of transferase activity GO:0051348 124 0.015
modification dependent protein catabolic process GO:0019941 209 0.015
antigen processing and presentation of exogenous antigen GO:0019884 4 0.015
response to mercury ion GO:0046689 4 0.015
cell projection assembly GO:0030031 126 0.015
cell part morphogenesis GO:0032990 137 0.015
regulation of anatomical structure morphogenesis GO:0022603 286 0.015
immune response GO:0006955 307 0.015
cellular response to starvation GO:0009267 58 0.015
cellular metal ion homeostasis GO:0006875 146 0.015
mating GO:0007618 1 0.015
secretion GO:0046903 254 0.015
generation of neurons GO:0048699 152 0.014
response to hydrogen peroxide GO:0042542 40 0.014
positive regulation of cell differentiation GO:0045597 211 0.014
neuromuscular process controlling balance GO:0050885 7 0.014
epidermis development GO:0008544 59 0.014
regulation of cell killing GO:0031341 22 0.014
tube morphogenesis GO:0035239 95 0.014
monovalent inorganic cation homeostasis GO:0055067 37 0.014
regulation of cellular component movement GO:0051270 334 0.014
amino acid transport GO:0006865 28 0.014
angiotensin maturation GO:0002003 2 0.014
phospholipid metabolic process GO:0006644 99 0.014
blood vessel remodeling GO:0001974 2 0.014
developmental process involved in reproduction GO:0003006 66 0.014
leukocyte mediated immunity GO:0002443 59 0.014
regulation of proteolysis GO:0030162 293 0.014
response to other organism GO:0051707 261 0.013
regulation of systemic arterial blood pressure by renin angiotensin GO:0003081 6 0.013
detection of stimulus GO:0051606 85 0.013
negative regulation of cellular amine metabolic process GO:0033239 3 0.013
regulation of cell activation GO:0050865 125 0.013
detection of chemical stimulus GO:0009593 55 0.013
cellular response to hydrogen peroxide GO:0070301 37 0.013
aminoglycan metabolic process GO:0006022 39 0.013
glucosamine containing compound catabolic process GO:1901072 3 0.013
negative regulation of proteolysis GO:0045861 132 0.013
cellular ketone metabolic process GO:0042180 80 0.013
tube closure GO:0060606 3 0.013
regulation of osteoblast differentiation GO:0045667 38 0.013
protein localization to membrane GO:0072657 160 0.013
detection of stimulus involved in sensory perception GO:0050906 43 0.013
regulation of leukocyte activation GO:0002694 115 0.012
cilium organization GO:0044782 68 0.012
regulation of lymphocyte activation GO:0051249 103 0.012
regulation of protein processing GO:0070613 150 0.012
cellular divalent inorganic cation homeostasis GO:0072503 128 0.012
adult locomotory behavior GO:0008344 1 0.012
negative regulation of phosphorus metabolic process GO:0010563 267 0.012
glycolipid catabolic process GO:0019377 8 0.012
head development GO:0060322 108 0.012
atp metabolic process GO:0046034 176 0.012
tissue remodeling GO:0048771 16 0.012
circadian behavior GO:0048512 2 0.012
ion transmembrane transport GO:0034220 338 0.012
developmental growth involved in morphogenesis GO:0060560 23 0.012
regulation of ph GO:0006885 20 0.012
dephosphorylation GO:0016311 209 0.012
cilium morphogenesis GO:0060271 75 0.012
tube development GO:0035295 125 0.012
response to oxygen levels GO:0070482 100 0.012
endochondral bone morphogenesis GO:0060350 3 0.012
multicellular organismal signaling GO:0035637 34 0.012
positive regulation of cell development GO:0010720 92 0.012
lytic vacuole organization GO:0080171 24 0.012
inorganic cation transmembrane transport GO:0098662 194 0.012
ubiquitin dependent protein catabolic process GO:0006511 206 0.011
collagen metabolic process GO:0032963 28 0.011
positive regulation of defense response GO:0031349 87 0.011
regulation of microtubule based process GO:0032886 74 0.011
reproductive structure development GO:0048608 55 0.011
macromolecule glycosylation GO:0043413 63 0.011
negative regulation of protein serine threonine kinase activity GO:0071901 57 0.011
lymphocyte activation GO:0046649 133 0.011
tissue morphogenesis GO:0048729 96 0.011
regulation of collagen metabolic process GO:0010712 15 0.011
regulation of cell division GO:0051302 116 0.011
sleep GO:0030431 2 0.011
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 69 0.011
regulation of blood pressure GO:0008217 30 0.011
intracellular protein transport GO:0006886 270 0.011
regulation of secretion by cell GO:1903530 177 0.011
positive regulation of transport GO:0051050 336 0.011
negative regulation of phosphate metabolic process GO:0045936 267 0.011
embryonic morphogenesis GO:0048598 85 0.011
retina homeostasis GO:0001895 42 0.010
positive regulation of myeloid leukocyte differentiation GO:0002763 24 0.010
endocytosis GO:0006897 159 0.010
oligosaccharide catabolic process GO:0009313 4 0.010
positive regulation of leukocyte degranulation GO:0043302 3 0.010
memory GO:0007613 3 0.010
regulation of cellular amine metabolic process GO:0033238 11 0.010
ribonucleoside monophosphate metabolic process GO:0009161 187 0.010
epithelial tube branching involved in lung morphogenesis GO:0060441 4 0.010
ceramide metabolic process GO:0006672 25 0.010
divalent inorganic cation transport GO:0072511 158 0.010
nephric duct development GO:0072176 4 0.010
protein ubiquitination GO:0016567 314 0.010
bone remodeling GO:0046849 11 0.010
metencephalon development GO:0022037 2 0.010

CTSA disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 295 1.000
lysosomal storage disease DOID:3211 47 1.000
inherited metabolic disorder DOID:655 242 1.000
lipid storage disease DOID:9455 28 1.000
neuronal ceroid lipofuscinosis DOID:14503 11 0.980
central nervous system disease DOID:331 186 0.793
nervous system disease DOID:863 431 0.793
cerebral degeneration DOID:1443 16 0.529
brain disease DOID:936 73 0.529
mucopolysaccharidosis DOID:12798 11 0.167
sphingolipidosis DOID:1927 14 0.136
leukodystrophy DOID:10579 8 0.105
retinal disease DOID:5679 118 0.065
sensory system disease DOID:0050155 203 0.065
eye and adnexa disease DOID:1492 150 0.065
eye disease DOID:5614 149 0.065
neurodegenerative disease DOID:1289 102 0.062
glycogen storage disease DOID:2747 10 0.046
carbohydrate metabolic disorder DOID:2978 55 0.046
glycogen metabolism disorder DOID:0050728 10 0.046
disease of mental health DOID:150 70 0.032
cognitive disorder DOID:1561 29 0.032
epilepsy syndrome DOID:1826 41 0.017
variable age at onset electroclinical syndrome DOID:0050706 8 0.017
electroclinical syndrome DOID:0050701 32 0.017
immune system disease DOID:2914 155 0.017
lymphatic system disease DOID:75 12 0.016
retinal degeneration DOID:8466 89 0.016