|
|
regulation of triglyceride catabolic process
|
GO:0010896 |
6 |
1.000
|
Yeast |
|
|
neutral lipid catabolic process
|
GO:0046461 |
12 |
1.000
|
Yeast |
|
|
negative regulation of mitotic anaphase promoting complex activity
|
GO:0060564 |
4 |
1.000
|
|
|
|
positive regulation of cardiac muscle cell proliferation
|
GO:0060045 |
2 |
1.000
|
|
|
|
regulation of triglyceride metabolic process
|
GO:0090207 |
11 |
1.000
|
Yeast |
|
|
oocyte maturation
|
GO:0001556 |
1 |
1.000
|
|
|
|
dna replication initiation
|
GO:0006270 |
6 |
1.000
|
Mouse |
|
|
g2 m transition of mitotic cell cycle
|
GO:0000086 |
41 |
1.000
|
|
|
|
regulation of meiotic cell cycle
|
GO:0051445 |
4 |
1.000
|
Yeast |
|
|
regulation of mitosis
|
GO:0007088 |
63 |
1.000
|
|
|
|
cell cycle g2 m phase transition
|
GO:0044839 |
43 |
1.000
|
|
|
|
g1 s transition of mitotic cell cycle
|
GO:0000082 |
78 |
1.000
|
Mouse |
|
|
dna replication
|
GO:0006260 |
116 |
1.000
|
Yeast Mouse |
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
1.000
|
Yeast |
|
|
negative regulation of mitotic cell cycle
|
GO:0045930 |
102 |
1.000
|
Yeast |
|
|
meiosis i
|
GO:0007127 |
4 |
1.000
|
Yeast |
|
|
mitotic cell cycle phase transition
|
GO:0044772 |
162 |
1.000
|
Mouse |
|
|
acylglycerol catabolic process
|
GO:0046464 |
12 |
1.000
|
Yeast |
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
1.000
|
|
|
|
positive regulation of mitotic cell cycle
|
GO:0045931 |
60 |
1.000
|
Yeast |
|
|
positive regulation of triglyceride metabolic process
|
GO:0090208 |
9 |
1.000
|
Yeast |
|
|
triglyceride catabolic process
|
GO:0019433 |
10 |
1.000
|
Yeast |
|
|
positive regulation of cell cycle process
|
GO:0090068 |
106 |
1.000
|
Yeast |
|
|
regulation of mitotic sister chromatid separation
|
GO:0010965 |
27 |
1.000
|
|
|
|
positive regulation of cardiac muscle tissue growth
|
GO:0055023 |
2 |
1.000
|
|
|
|
positive regulation of fibroblast proliferation
|
GO:0048146 |
21 |
1.000
|
|
|
|
positive regulation of meiotic cell cycle
|
GO:0051446 |
2 |
1.000
|
Yeast |
|
|
mitotic sister chromatid segregation
|
GO:0000070 |
53 |
1.000
|
|
|
|
negative regulation of cell cycle phase transition
|
GO:1901988 |
89 |
1.000
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.999
|
Yeast Mouse |
|
|
regulation of cell cycle phase transition
|
GO:1901987 |
126 |
0.999
|
|
|
|
regulation of mitotic metaphase anaphase transition
|
GO:0030071 |
26 |
0.999
|
|
|
|
g2 dna damage checkpoint
|
GO:0031572 |
26 |
0.999
|
|
|
|
regulation of cardiac muscle cell proliferation
|
GO:0060043 |
4 |
0.999
|
|
|
|
negative regulation of transcription from rna polymerase ii promoter
|
GO:0000122 |
281 |
0.999
|
|
|
|
regulation of mitotic cell cycle phase transition
|
GO:1901990 |
118 |
0.999
|
|
|
|
chromatin organization
|
GO:0006325 |
351 |
0.999
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.999
|
|
|
|
positive regulation of cell cycle
|
GO:0045787 |
140 |
0.999
|
Yeast |
|
|
mitotic nuclear division
|
GO:0007067 |
119 |
0.999
|
|
|
|
negative regulation of ubiquitin protein ligase activity involved in mitotic cell cycle
|
GO:0051436 |
4 |
0.999
|
|
|
|
mitotic dna integrity checkpoint
|
GO:0044774 |
30 |
0.998
|
|
|
|
dna dependent dna replication
|
GO:0006261 |
44 |
0.998
|
Yeast Mouse |
|
|
dna integrity checkpoint
|
GO:0031570 |
71 |
0.998
|
|
|
|
neuronal stem cell division
|
GO:0036445 |
1 |
0.998
|
|
|
|
asymmetric neuroblast division
|
GO:0055059 |
1 |
0.998
|
|
|
|
neuroblast division
|
GO:0055057 |
1 |
0.998
|
|
|
|
dna damage checkpoint
|
GO:0000077 |
68 |
0.998
|
|
|
|
positive regulation of dna metabolic process
|
GO:0051054 |
73 |
0.998
|
Yeast Mouse |
|
|
negative regulation of chromosome organization
|
GO:2001251 |
48 |
0.998
|
Yeast |
|
|
organ morphogenesis
|
GO:0009887 |
147 |
0.997
|
|
|
|
7 methylguanosine mrna capping
|
GO:0006370 |
7 |
0.997
|
Yeast |
|
|
asymmetric stem cell division
|
GO:0098722 |
1 |
0.997
|
|
|
|
phosphorylation of rna polymerase ii c terminal domain
|
GO:0070816 |
3 |
0.997
|
Yeast |
|
|
metaphase anaphase transition of cell cycle
|
GO:0044784 |
21 |
0.997
|
|
|
|
positive regulation of mitotic cell cycle phase transition
|
GO:1901992 |
19 |
0.996
|
|
|
|
cell cycle dna replication
|
GO:0044786 |
11 |
0.996
|
Yeast |
|
|
epithelial cell differentiation
|
GO:0030855 |
141 |
0.995
|
Human |
|
|
somatic stem cell division
|
GO:0048103 |
1 |
0.995
|
|
|
|
negative regulation of mitotic cell cycle phase transition
|
GO:1901991 |
85 |
0.995
|
|
|
|
regulation of metaphase anaphase transition of cell cycle
|
GO:1902099 |
26 |
0.995
|
|
|
|
regulation of dna replication
|
GO:0006275 |
68 |
0.995
|
Yeast Mouse |
|
|
negative regulation of mitotic metaphase anaphase transition
|
GO:0045841 |
17 |
0.995
|
|
|
|
glycerolipid catabolic process
|
GO:0046503 |
18 |
0.994
|
Yeast |
|
|
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic process
|
GO:0031145 |
25 |
0.994
|
|
|
|
regeneration
|
GO:0031099 |
4 |
0.994
|
Rat |
|
|
chromosome separation
|
GO:0051304 |
23 |
0.994
|
|
|
|
oogenesis
|
GO:0048477 |
2 |
0.993
|
|
|
|
negative regulation of transcription involved in g1 s transition of mitotic cell cycle
|
GO:0071930 |
2 |
0.993
|
|
|
|
protein dna complex assembly
|
GO:0065004 |
64 |
0.992
|
|
|
|
metaphase anaphase transition of mitotic cell cycle
|
GO:0007091 |
21 |
0.991
|
|
|
|
mitotic dna damage checkpoint
|
GO:0044773 |
28 |
0.990
|
|
|
|
exit from mitosis
|
GO:0010458 |
10 |
0.989
|
|
|
|
chromosome segregation
|
GO:0007059 |
114 |
0.989
|
Yeast |
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.989
|
Yeast |
|
|
regulation of cyclin dependent protein serine threonine kinase activity
|
GO:0000079 |
36 |
0.988
|
|
|
|
mitotic sister chromatid separation
|
GO:0051306 |
18 |
0.987
|
|
|
|
positive regulation of chromosome segregation
|
GO:0051984 |
9 |
0.987
|
|
|
|
cell cycle g1 s phase transition
|
GO:0044843 |
80 |
0.986
|
Mouse |
|
|
7 methylguanosine rna capping
|
GO:0009452 |
9 |
0.986
|
Yeast |
|
|
cellular protein catabolic process
|
GO:0044257 |
261 |
0.985
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.985
|
|
|
|
negative regulation of protein dephosphorylation
|
GO:0035308 |
3 |
0.983
|
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.983
|
|
|
|
sister chromatid segregation
|
GO:0000819 |
54 |
0.983
|
|
|
|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
156 |
0.982
|
|
|
|
regulation of nuclear division
|
GO:0051783 |
65 |
0.982
|
|
|
|
dna packaging
|
GO:0006323 |
77 |
0.982
|
|
|
|
negative regulation of cell cycle process
|
GO:0010948 |
121 |
0.982
|
Yeast |
|
|
cellular response to iron ion
|
GO:0071281 |
1 |
0.982
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
189 |
0.982
|
Yeast |
|
|
neuron fate commitment
|
GO:0048663 |
2 |
0.981
|
|
|
|
mitotic cell cycle checkpoint
|
GO:0007093 |
68 |
0.981
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.980
|
Mouse |
|
|
modification dependent protein catabolic process
|
GO:0019941 |
209 |
0.980
|
|
|
|
muscle cell proliferation
|
GO:0033002 |
35 |
0.979
|
|
|
|
oocyte differentiation
|
GO:0009994 |
2 |
0.978
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.977
|
|
|
|
oocyte development
|
GO:0048599 |
1 |
0.977
|
|
|
|
regulation of ubiquitin protein transferase activity
|
GO:0051438 |
28 |
0.973
|
|
|
|
cell cycle phase transition
|
GO:0044770 |
173 |
0.973
|
Mouse |
|
|
regulation of mitotic sister chromatid segregation
|
GO:0033047 |
27 |
0.973
|
|
|
|
covalent chromatin modification
|
GO:0016569 |
254 |
0.973
|
|
|
|
regulation of fibroblast proliferation
|
GO:0048145 |
32 |
0.972
|
|
|
|
cell cycle checkpoint
|
GO:0000075 |
117 |
0.971
|
|
|
|
regulation of exit from mitosis
|
GO:0007096 |
6 |
0.967
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
244 |
0.967
|
|
|
|
somatic stem cell maintenance
|
GO:0035019 |
4 |
0.967
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.966
|
|
|
|
cytokinesis
|
GO:0000910 |
96 |
0.966
|
|
|
|
regulation of g1 s transition of mitotic cell cycle
|
GO:2000045 |
40 |
0.963
|
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
206 |
0.962
|
|
|
|
regulation of sister chromatid segregation
|
GO:0033045 |
27 |
0.961
|
|
|
|
regulation of proteasomal ubiquitin dependent protein catabolic process
|
GO:0032434 |
71 |
0.960
|
|
|
|
regulation of lipid catabolic process
|
GO:0050994 |
23 |
0.959
|
Yeast |
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.956
|
|
|
|
proteasomal protein catabolic process
|
GO:0010498 |
176 |
0.950
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.947
|
|
|
|
double strand break repair
|
GO:0006302 |
101 |
0.946
|
Yeast |
|
|
regulation of cell cycle arrest
|
GO:0071156 |
36 |
0.944
|
|
|
|
nuclear dna replication
|
GO:0033260 |
6 |
0.942
|
Yeast |
|
|
negative regulation of dna metabolic process
|
GO:0051053 |
57 |
0.937
|
Yeast |
|
|
negative regulation of g1 s transition of mitotic cell cycle
|
GO:2000134 |
29 |
0.935
|
|
|
|
segmentation
|
GO:0035282 |
4 |
0.935
|
|
|
|
regulation of cell division
|
GO:0051302 |
116 |
0.932
|
Yeast |
|
|
protein modification by small protein conjugation
|
GO:0032446 |
342 |
0.929
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.929
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.927
|
Human |
|
|
cell division
|
GO:0051301 |
168 |
0.926
|
Yeast |
|
|
negative regulation of chromosome segregation
|
GO:0051985 |
18 |
0.925
|
Yeast |
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.923
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.920
|
|
|
|
cell fate determination
|
GO:0001709 |
3 |
0.920
|
|
|
|
regulation of cell cycle g1 s phase transition
|
GO:1902806 |
42 |
0.917
|
|
|
|
regulation of dna dependent dna replication initiation
|
GO:0030174 |
3 |
0.915
|
Mouse |
|
|
peripheral nervous system development
|
GO:0007422 |
2 |
0.913
|
|
|
|
regulation of dna metabolic process
|
GO:0051052 |
153 |
0.913
|
Yeast Mouse |
|
|
neuroblast proliferation
|
GO:0007405 |
4 |
0.912
|
|
|
|
peptidyl serine phosphorylation
|
GO:0018105 |
101 |
0.909
|
Human Yeast |
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.905
|
|
|
|
reproductive process
|
GO:0022414 |
106 |
0.902
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.892
|
|
|
|
triglyceride metabolic process
|
GO:0006641 |
23 |
0.889
|
Yeast |
|
|
autophagic cell death
|
GO:0048102 |
3 |
0.878
|
|
|
|
ventricular cardiac muscle cell differentiation
|
GO:0055012 |
1 |
0.877
|
|
|
|
cyclin catabolic process
|
GO:0008054 |
6 |
0.875
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.864
|
Human |
|
|
regulation of proteasomal protein catabolic process
|
GO:0061136 |
87 |
0.859
|
|
|
|
regulation of chromosome segregation
|
GO:0051983 |
44 |
0.859
|
Yeast |
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.854
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
380 |
0.852
|
Yeast |
|
|
negative regulation of cell cycle
|
GO:0045786 |
193 |
0.850
|
Yeast |
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
212 |
0.849
|
|
|
|
positive regulation of attachment of spindle microtubules to kinetochore
|
GO:0051987 |
2 |
0.844
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.843
|
Human |
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
127 |
0.839
|
|
|
|
dna repair
|
GO:0006281 |
198 |
0.838
|
Yeast |
|
|
histone modification
|
GO:0016570 |
251 |
0.837
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.835
|
|
|
|
developmental process involved in reproduction
|
GO:0003006 |
66 |
0.828
|
|
|
|
response to cytokine
|
GO:0034097 |
232 |
0.821
|
|
|
|
positive regulation of heart growth
|
GO:0060421 |
2 |
0.814
|
|
|
|
response to ethanol
|
GO:0045471 |
11 |
0.806
|
Rat |
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.801
|
|
|
|
negative regulation of sister chromatid segregation
|
GO:0033046 |
17 |
0.801
|
|
|
|
positive regulation of lipid catabolic process
|
GO:0050996 |
13 |
0.798
|
Yeast |
|
|
regulation of protein import into nucleus translocation
|
GO:0033158 |
10 |
0.793
|
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
176 |
0.790
|
Yeast |
|
|
mitotic g2 dna damage checkpoint
|
GO:0007095 |
7 |
0.788
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.785
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.782
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.774
|
|
|
|
peptidyl threonine modification
|
GO:0018210 |
45 |
0.773
|
Human |
|
|
nuclear division
|
GO:0000280 |
128 |
0.770
|
Yeast |
|
|
sensory organ development
|
GO:0007423 |
52 |
0.768
|
Rat |
|
|
regulation of chromosome organization
|
GO:0033044 |
103 |
0.757
|
Yeast |
|
|
regulation of protein catabolic process
|
GO:0042176 |
155 |
0.757
|
|
|
|
circulatory system development
|
GO:0072359 |
262 |
0.753
|
|
|
|
response to nitrogen compound
|
GO:1901698 |
184 |
0.752
|
Rat |
|
|
reproduction
|
GO:0000003 |
63 |
0.750
|
Yeast |
|
|
regulation of dna dependent dna replication
|
GO:0090329 |
19 |
0.744
|
Yeast Mouse |
|
|
cell type specific apoptotic process
|
GO:0097285 |
125 |
0.744
|
|
|
|
regulation of cardiac muscle tissue growth
|
GO:0055021 |
4 |
0.743
|
|
|
|
response to metal ion
|
GO:0010038 |
84 |
0.741
|
Rat |
|
|
regulation of peptidase activity
|
GO:0052547 |
180 |
0.741
|
|
|
|
microtubule polymerization or depolymerization
|
GO:0031109 |
37 |
0.735
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.728
|
|
|
|
regulation of microtubule based process
|
GO:0032886 |
74 |
0.725
|
Yeast |
|
|
regulation of growth
|
GO:0040008 |
165 |
0.725
|
Yeast |
|
|
single organism reproductive process
|
GO:0044702 |
98 |
0.720
|
|
|
|
meiotic nuclear division
|
GO:0007126 |
10 |
0.708
|
Yeast |
|
|
protein maturation
|
GO:0051604 |
233 |
0.707
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.706
|
|
|
|
mitotic g1 dna damage checkpoint
|
GO:0031571 |
17 |
0.706
|
|
|
|
regulation of mitotic spindle organization
|
GO:0060236 |
6 |
0.702
|
|
|
|
negative regulation of mitosis
|
GO:0045839 |
24 |
0.695
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.690
|
|
|
|
cellular response to abiotic stimulus
|
GO:0071214 |
117 |
0.679
|
|
|
|
dna damage response signal transduction by p53 class mediator
|
GO:0030330 |
44 |
0.671
|
|
|
|
chromosome condensation
|
GO:0030261 |
15 |
0.668
|
|
|
|
positive regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043280 |
69 |
0.668
|
|
|
|
cell cell signaling involved in cell fate commitment
|
GO:0045168 |
5 |
0.666
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.665
|
|
|
|
cell aging
|
GO:0007569 |
52 |
0.664
|
|
|
|
regulation of microtubule polymerization or depolymerization
|
GO:0031110 |
27 |
0.662
|
|
|
|
embryo development
|
GO:0009790 |
123 |
0.662
|
|
|
|
microtubule based process
|
GO:0007017 |
210 |
0.662
|
Yeast |
|
|
organelle fission
|
GO:0048285 |
149 |
0.662
|
Yeast |
|
|
regulation of lipid metabolic process
|
GO:0019216 |
96 |
0.660
|
Yeast |
|
|
spindle stabilization
|
GO:0043146 |
4 |
0.658
|
|
|
|
negative regulation of ubiquitin protein transferase activity
|
GO:0051444 |
8 |
0.652
|
|
|
|
negative regulation of microtubule polymerization or depolymerization
|
GO:0031111 |
17 |
0.649
|
|
|
|
regulation of protein modification by small protein conjugation or removal
|
GO:1903320 |
107 |
0.645
|
|
|
|
growth
|
GO:0040007 |
202 |
0.644
|
Yeast |
|
|
generation of neurons
|
GO:0048699 |
152 |
0.639
|
|
|
|
negative regulation of metaphase anaphase transition of cell cycle
|
GO:1902100 |
17 |
0.638
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
204 |
0.635
|
Rat |
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.633
|
|
|
|
regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903050 |
91 |
0.625
|
|
|
|
positive regulation of meiosis
|
GO:0045836 |
2 |
0.621
|
|
|
|
response to inorganic substance
|
GO:0010035 |
127 |
0.619
|
Rat |
|
|
negative regulation of cell cycle g1 s phase transition
|
GO:1902807 |
29 |
0.618
|
|
|
|
acylglycerol metabolic process
|
GO:0006639 |
27 |
0.618
|
Yeast |
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.617
|
|
|
|
dna double strand break processing
|
GO:0000729 |
10 |
0.616
|
Yeast |
|
|
dna conformation change
|
GO:0071103 |
113 |
0.615
|
|
|
|
negative regulation of double strand break repair via nonhomologous end joining
|
GO:2001033 |
1 |
0.611
|
Yeast |
|
|
peptidyl threonine phosphorylation
|
GO:0018107 |
41 |
0.604
|
Human |
|
|
intrinsic apoptotic signaling pathway in response to dna damage
|
GO:0008630 |
50 |
0.595
|
|
|
|
cellular response to hypoxia
|
GO:0071456 |
51 |
0.593
|
|
|
|
regulation of cellular protein catabolic process
|
GO:1903362 |
96 |
0.592
|
|
|
|
protein complex disassembly
|
GO:0043241 |
52 |
0.591
|
|
|
|
cell cycle arrest
|
GO:0007050 |
71 |
0.578
|
|
|
|
protein ubiquitination
|
GO:0016567 |
314 |
0.575
|
|
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.573
|
|
|
|
response to transition metal nanoparticle
|
GO:1990267 |
29 |
0.565
|
|
|
|
regulation of transcription involved in g1 s transition of mitotic cell cycle
|
GO:0000083 |
8 |
0.563
|
|
|
|
stem cell division
|
GO:0017145 |
2 |
0.560
|
|
|
|
peptidyl serine modification
|
GO:0018209 |
106 |
0.560
|
Human Yeast |
|
|
jak stat cascade
|
GO:0007259 |
46 |
0.559
|
Fly |
|
|
regulation of g0 to g1 transition
|
GO:0070316 |
2 |
0.559
|
|
|
|
cellular component disassembly
|
GO:0022411 |
92 |
0.555
|
|
|
|
cardiac muscle cell development
|
GO:0055013 |
5 |
0.544
|
|
|
|
positive regulation of response to dna damage stimulus
|
GO:2001022 |
43 |
0.543
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.538
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
119 |
0.535
|
|
|
|
mitotic spindle stabilization
|
GO:0043148 |
2 |
0.535
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.534
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.534
|
|
|
|
regulation of protein ubiquitination
|
GO:0031396 |
95 |
0.531
|
|
|
|
negative regulation of organelle organization
|
GO:0010639 |
126 |
0.530
|
Yeast |
|
|
negative regulation of mitotic sister chromatid separation
|
GO:2000816 |
17 |
0.523
|
|
|
|
stem cell differentiation
|
GO:0048863 |
93 |
0.511
|
|
|
|
positive regulation of cell division
|
GO:0051781 |
59 |
0.508
|
|
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.504
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.501
|
Rat |
|
|
regulation of meiosis
|
GO:0040020 |
3 |
0.498
|
|
|
|
response to purine containing compound
|
GO:0014074 |
40 |
0.497
|
Rat |
|
|
positive regulation of leukocyte activation
|
GO:0002696 |
80 |
0.494
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.493
|
Yeast |
|
|
positive regulation of dna replication
|
GO:0045740 |
35 |
0.492
|
Yeast Mouse |
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.491
|
|
|
|
positive regulation of cell cycle g2 m phase transition
|
GO:1902751 |
8 |
0.490
|
|
|
|
mitotic cell cycle arrest
|
GO:0071850 |
4 |
0.486
|
|
|
|
muscle cell development
|
GO:0055001 |
29 |
0.484
|
|
|
|
stem cell development
|
GO:0048864 |
69 |
0.483
|
|
|
|
rna stabilization
|
GO:0043489 |
18 |
0.481
|
|
|
|
erythrocyte differentiation
|
GO:0030218 |
28 |
0.480
|
|
|
|
protein processing
|
GO:0016485 |
226 |
0.480
|
|
|
|
immune response
|
GO:0006955 |
307 |
0.478
|
|
|
|
regulation of embryonic development
|
GO:0045995 |
20 |
0.471
|
|
|
|
antimicrobial humoral response
|
GO:0019730 |
26 |
0.471
|
|
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
324 |
0.470
|
|
|
|
multi organism reproductive process
|
GO:0044703 |
54 |
0.470
|
|
|
|
sex differentiation
|
GO:0007548 |
45 |
0.466
|
|
|
|
reproductive structure development
|
GO:0048608 |
55 |
0.461
|
|
|
|
humoral immune response
|
GO:0006959 |
49 |
0.461
|
|
|
|
regulation of microtubule cytoskeleton organization
|
GO:0070507 |
61 |
0.454
|
Yeast |
|
|
regulation of g2 m transition of mitotic cell cycle
|
GO:0010389 |
20 |
0.453
|
|
|
|
chromatin remodeling
|
GO:0006338 |
55 |
0.449
|
Yeast |
|
|
dna endoreduplication
|
GO:0042023 |
5 |
0.441
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.440
|
Yeast |
|
|
muscle cell differentiation
|
GO:0042692 |
63 |
0.432
|
|
|
|
tube development
|
GO:0035295 |
125 |
0.430
|
|
|
|
mitotic g2 m transition checkpoint
|
GO:0044818 |
9 |
0.429
|
|
|
|
gene silencing
|
GO:0016458 |
49 |
0.429
|
|
|
|
regulation of binding
|
GO:0051098 |
111 |
0.426
|
|
|
|
establishment of nucleus localization
|
GO:0040023 |
1 |
0.426
|
|
|
|
positive regulation of cardiac muscle tissue development
|
GO:0055025 |
6 |
0.426
|
|
|
|
gland development
|
GO:0048732 |
48 |
0.412
|
|
|
|
mitotic metaphase plate congression
|
GO:0007080 |
14 |
0.410
|
|
|
|
signal transduction in response to dna damage
|
GO:0042770 |
57 |
0.409
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.404
|
|
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
41 |
0.396
|
|
|
|
protein localization to kinetochore
|
GO:0034501 |
10 |
0.395
|
Human |
|
|
positive regulation of nuclear division
|
GO:0051785 |
27 |
0.393
|
|
|
|
negative regulation of protein maturation
|
GO:1903318 |
142 |
0.390
|
|
|
|
positive regulation of g2 m transition of mitotic cell cycle
|
GO:0010971 |
8 |
0.382
|
|
|
|
chromatin modification
|
GO:0016568 |
298 |
0.379
|
|
|
|
regulation of spindle organization
|
GO:0090224 |
10 |
0.378
|
|
|
|
heart growth
|
GO:0060419 |
6 |
0.375
|
|
|
|
organelle assembly
|
GO:0070925 |
176 |
0.373
|
|
|
|
t cell homeostasis
|
GO:0043029 |
3 |
0.373
|
|
|
|
digestive tract development
|
GO:0048565 |
75 |
0.366
|
|
|
|
response to toxic substance
|
GO:0009636 |
37 |
0.365
|
Rat |
|
|
regulation of erythrocyte differentiation
|
GO:0045646 |
17 |
0.362
|
|
|
|
regulation of dna repair
|
GO:0006282 |
47 |
0.359
|
Yeast |
|
|
fibroblast proliferation
|
GO:0048144 |
33 |
0.357
|
|
|
|
cell fate commitment
|
GO:0045165 |
27 |
0.352
|
|
|
|
dna catabolic process exonucleolytic
|
GO:0000738 |
17 |
0.352
|
Yeast |
|
|
male meiosis
|
GO:0007140 |
1 |
0.348
|
|
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.347
|
|
|
|
activation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0006919 |
49 |
0.346
|
|
|
|
negative regulation of dna replication
|
GO:0008156 |
29 |
0.345
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.343
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.339
|
|
|
|
negative regulation of mitotic sister chromatid segregation
|
GO:0033048 |
17 |
0.332
|
|
|
|
histone phosphorylation
|
GO:0016572 |
16 |
0.331
|
|
|
|
response to external biotic stimulus
|
GO:0043207 |
261 |
0.325
|
|
|
|
regulation of double strand break repair
|
GO:2000779 |
22 |
0.323
|
Yeast |
|
|
hemopoiesis
|
GO:0030097 |
180 |
0.319
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.318
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.317
|
|
|
|
cellular protein complex assembly
|
GO:0043623 |
188 |
0.314
|
|
|
|
regulation of microtubule polymerization
|
GO:0031113 |
12 |
0.308
|
|
|
|
cellular response to inorganic substance
|
GO:0071241 |
45 |
0.304
|
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
142 |
0.303
|
|
|
|
cellular response to lithium ion
|
GO:0071285 |
2 |
0.303
|
|
|
|
cellular response to decreased oxygen levels
|
GO:0036294 |
51 |
0.300
|
|
|
|
erythrocyte homeostasis
|
GO:0034101 |
31 |
0.298
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.294
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
303 |
0.293
|
Yeast |
|
|
negative regulation of proteolysis
|
GO:0045861 |
132 |
0.293
|
|
|
|
development of primary sexual characteristics
|
GO:0045137 |
35 |
0.288
|
|
|
|
protein dna complex subunit organization
|
GO:0071824 |
80 |
0.287
|
|
|
|
multicellular organism reproduction
|
GO:0032504 |
42 |
0.284
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.283
|
|
|
|
meiotic cell cycle
|
GO:0051321 |
13 |
0.283
|
Yeast |
|
|
non recombinational repair
|
GO:0000726 |
14 |
0.281
|
Yeast |
|
|
cell maturation
|
GO:0048469 |
11 |
0.279
|
|
|
|
dna biosynthetic process
|
GO:0071897 |
40 |
0.278
|
|
|
|
response to drug
|
GO:0042493 |
81 |
0.272
|
Rat |
|
|
positive regulation of cytoskeleton organization
|
GO:0051495 |
83 |
0.266
|
Yeast |
|
|
urogenital system development
|
GO:0001655 |
65 |
0.266
|
|
|
|
regulation of chromatin binding
|
GO:0035561 |
3 |
0.262
|
|
|
|
response to estrogen
|
GO:0043627 |
47 |
0.261
|
Rat |
|
|
sister chromatid cohesion
|
GO:0007062 |
24 |
0.252
|
Yeast |
|
|
fertilization
|
GO:0009566 |
12 |
0.250
|
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
123 |
0.250
|
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.247
|
|
|
|
microtubule depolymerization
|
GO:0007019 |
18 |
0.243
|
|
|
|
positive regulation of dna templated transcription elongation
|
GO:0032786 |
18 |
0.242
|
|
|
|
histone serine phosphorylation
|
GO:0035404 |
4 |
0.241
|
|
|
|
zymogen activation
|
GO:0031638 |
70 |
0.239
|
|
|
|
developmental maturation
|
GO:0021700 |
28 |
0.238
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.236
|
|
|
|
neurogenesis
|
GO:0022008 |
169 |
0.236
|
|
|
|
cellular response to metal ion
|
GO:0071248 |
43 |
0.234
|
|
|
|
microtubule anchoring
|
GO:0034453 |
24 |
0.234
|
|
|
|
negative regulation of dephosphorylation
|
GO:0035305 |
63 |
0.233
|
|
|
|
kidney development
|
GO:0001822 |
53 |
0.232
|
|
|
|
embryo development ending in birth or egg hatching
|
GO:0009792 |
34 |
0.230
|
|
|
|
response to steroid hormone
|
GO:0048545 |
80 |
0.226
|
Rat |
|
|
regulation of cell cycle g2 m phase transition
|
GO:1902749 |
22 |
0.226
|
|
|
|
attachment of spindle microtubules to kinetochore
|
GO:0008608 |
17 |
0.225
|
|
|
|
positive regulation of chromosome organization
|
GO:2001252 |
41 |
0.224
|
|
|
|
mrna processing
|
GO:0006397 |
133 |
0.221
|
Yeast |
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043281 |
116 |
0.218
|
|
|
|
cohesin localization to chromatin
|
GO:0071921 |
4 |
0.218
|
|
|
|
striated muscle cell proliferation
|
GO:0014855 |
7 |
0.216
|
|
|
|
cofactor metabolic process
|
GO:0051186 |
87 |
0.215
|
|
|
|
ribonucleoside monophosphate metabolic process
|
GO:0009161 |
187 |
0.214
|
|
|
|
nuclear transport
|
GO:0051169 |
179 |
0.212
|
|
|
|
immune system development
|
GO:0002520 |
195 |
0.208
|
|
|
|
microtubule cytoskeleton organization involved in mitosis
|
GO:1902850 |
15 |
0.208
|
|
|
|
positive regulation of proteasomal protein catabolic process
|
GO:1901800 |
35 |
0.207
|
|
|
|
negative regulation of cell differentiation
|
GO:0045596 |
171 |
0.205
|
|
|
|
response to activity
|
GO:0014823 |
0 |
0.205
|
|
|
|
heart development
|
GO:0007507 |
95 |
0.204
|
|
|
|
cardiac muscle cell differentiation
|
GO:0055007 |
15 |
0.202
|
|
|
|
developmental programmed cell death
|
GO:0010623 |
3 |
0.202
|
|
|
|
regulation of mrna metabolic process
|
GO:1903311 |
53 |
0.202
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
177 |
0.198
|
Yeast |
|
|
organelle localization
|
GO:0051640 |
84 |
0.198
|
|
|
|
gonad development
|
GO:0008406 |
34 |
0.197
|
|
|
|
positive regulation of cell cycle phase transition
|
GO:1901989 |
22 |
0.196
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
156 |
0.195
|
Rat |
|
|
multicellular organismal reproductive process
|
GO:0048609 |
40 |
0.195
|
|
|
|
negative regulation of cellular catabolic process
|
GO:0031330 |
83 |
0.195
|
|
|
|
double strand break repair via nonhomologous end joining
|
GO:0006303 |
10 |
0.192
|
Yeast |
|
|
positive regulation of muscle organ development
|
GO:0048636 |
7 |
0.191
|
|
|
|
mitotic g1 s transition checkpoint
|
GO:0044819 |
17 |
0.190
|
|
|
|
cellular response to toxic substance
|
GO:0097237 |
4 |
0.186
|
|
|
|
response to hypoxia
|
GO:0001666 |
96 |
0.186
|
|
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.184
|
Rat |
|
|
compound eye development
|
GO:0048749 |
1 |
0.183
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
195 |
0.181
|
Yeast |
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.181
|
|
|
|
regulation of striated muscle tissue development
|
GO:0016202 |
26 |
0.180
|
|
|
|
ovulation cycle process
|
GO:0022602 |
9 |
0.179
|
|
|
|
atp catabolic process
|
GO:0006200 |
157 |
0.177
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
170 |
0.177
|
|
|
|
macromolecular complex disassembly
|
GO:0032984 |
60 |
0.174
|
|
|
|
glomerular epithelial cell development
|
GO:0072310 |
3 |
0.173
|
|
|
|
single organism nuclear import
|
GO:1902593 |
104 |
0.171
|
|
|
|
regulation of dephosphorylation
|
GO:0035303 |
96 |
0.171
|
|
|
|
response to nerve growth factor
|
GO:1990089 |
6 |
0.167
|
|
|
|
cellular protein complex disassembly
|
GO:0043624 |
36 |
0.163
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.163
|
Rat |
|
|
positive regulation of cell cycle arrest
|
GO:0071158 |
23 |
0.163
|
|
|
|
negative regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903051 |
35 |
0.162
|
|
|
|
stem cell maintenance
|
GO:0019827 |
19 |
0.162
|
|
|
|
protein polyubiquitination
|
GO:0000209 |
110 |
0.159
|
|
|
|
epithelial cell development
|
GO:0002064 |
34 |
0.158
|
|
|
|
regulation of protein processing
|
GO:0070613 |
150 |
0.158
|
|
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.158
|
|
|
|
signal transduction by p53 class mediator
|
GO:0072331 |
72 |
0.157
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.156
|
|
|
|
dephosphorylation
|
GO:0016311 |
209 |
0.155
|
|
|
|
cardiocyte differentiation
|
GO:0035051 |
23 |
0.154
|
|
|
|
regulation of protein import into nucleus
|
GO:0042306 |
78 |
0.152
|
|
|
|
chordate embryonic development
|
GO:0043009 |
34 |
0.152
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
211 |
0.150
|
|
|
|
regulation of ligase activity
|
GO:0051340 |
29 |
0.145
|
|
|
|
mitotic spindle checkpoint
|
GO:0071174 |
18 |
0.145
|
|
|
|
response to corticosteroid
|
GO:0031960 |
15 |
0.142
|
|
|
|
cellular response to oxygen levels
|
GO:0071453 |
55 |
0.141
|
|
|
|
positive regulation of growth
|
GO:0045927 |
58 |
0.140
|
|
|
|
positive regulation of cysteine type endopeptidase activity
|
GO:2001056 |
79 |
0.138
|
|
|
|
g1 dna damage checkpoint
|
GO:0044783 |
18 |
0.134
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.133
|
|
|
|
negative regulation of cell division
|
GO:0051782 |
31 |
0.132
|
|
|
|
microtubule polymerization
|
GO:0046785 |
18 |
0.131
|
|
|
|
enteroendocrine cell differentiation
|
GO:0035883 |
6 |
0.130
|
|
|
|
centrosome organization
|
GO:0051297 |
58 |
0.130
|
|
|
|
cell cell signaling
|
GO:0007267 |
155 |
0.130
|
|
|
|
female gonad development
|
GO:0008585 |
10 |
0.128
|
|
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.127
|
Human |
|
|
activation of cysteine type endopeptidase activity
|
GO:0097202 |
57 |
0.126
|
|
|
|
dna damage response signal transduction resulting in transcription
|
GO:0042772 |
12 |
0.126
|
|
|
|
atp metabolic process
|
GO:0046034 |
176 |
0.123
|
|
|
|
meiotic chromosome segregation
|
GO:0045132 |
4 |
0.122
|
|
|
|
regulation of heart growth
|
GO:0060420 |
4 |
0.120
|
|
|
|
regulation of protein depolymerization
|
GO:1901879 |
22 |
0.119
|
|
|
|
cellular process involved in reproduction in multicellular organism
|
GO:0022412 |
15 |
0.118
|
|
|
|
neutral lipid metabolic process
|
GO:0006638 |
27 |
0.117
|
Yeast |
|
|
signal transduction involved in mitotic cell cycle checkpoint
|
GO:0072413 |
13 |
0.117
|
|
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.115
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.115
|
|
|
|
internal peptidyl lysine acetylation
|
GO:0018393 |
97 |
0.114
|
|
|
|
positive regulation of endopeptidase activity
|
GO:0010950 |
84 |
0.114
|
|
|
|
protein targeting to nucleus
|
GO:0044744 |
104 |
0.112
|
|
|
|
negative regulation of response to dna damage stimulus
|
GO:2001021 |
33 |
0.112
|
Yeast |
|
|
positive regulation of dna repair
|
GO:0045739 |
25 |
0.112
|
|
|
|
cellular response to lipid
|
GO:0071396 |
127 |
0.111
|
|
|
|
nucleic acid phosphodiester bond hydrolysis
|
GO:0090305 |
102 |
0.110
|
Yeast |
|
|
ovulation cycle
|
GO:0042698 |
9 |
0.110
|
|
|
|
regulation of mrna processing
|
GO:0050684 |
48 |
0.105
|
|
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.105
|
|
|
|
positive regulation of protein polyubiquitination
|
GO:1902916 |
3 |
0.105
|
|
|
|
positive regulation of cellular protein catabolic process
|
GO:1903364 |
37 |
0.105
|
|
|
|
regulation of protein complex assembly
|
GO:0043254 |
147 |
0.104
|
|
|
|
metaphase plate congression
|
GO:0051310 |
18 |
0.104
|
|
|
|
dna recombination
|
GO:0006310 |
77 |
0.104
|
Yeast |
|
|
negative regulation of proteasomal protein catabolic process
|
GO:1901799 |
32 |
0.104
|
|
|
|
neuron projection development
|
GO:0031175 |
106 |
0.102
|
|
|
|
peptidyl tyrosine dephosphorylation
|
GO:0035335 |
36 |
0.102
|
|
|
|
regulation of endopeptidase activity
|
GO:0052548 |
170 |
0.101
|
|
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
127 |
0.101
|
|
|
|
dna catabolic process
|
GO:0006308 |
49 |
0.100
|
Yeast |
|
|
dna damage response signal transduction by p53 class mediator resulting in transcription of p21 class mediator
|
GO:0006978 |
11 |
0.100
|
|
|
|
negative regulation of cytoskeleton organization
|
GO:0051494 |
45 |
0.100
|
|
|
|
male gamete generation
|
GO:0048232 |
22 |
0.099
|
|
|
|
intracellular receptor signaling pathway
|
GO:0030522 |
104 |
0.098
|
|
|
|
negative regulation of cellular protein catabolic process
|
GO:1903363 |
38 |
0.098
|
|
|
|
lipid catabolic process
|
GO:0016042 |
84 |
0.097
|
Yeast |
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.096
|
Yeast |
|
|
response to fatty acid
|
GO:0070542 |
13 |
0.096
|
|
|
|
response to ionizing radiation
|
GO:0010212 |
65 |
0.096
|
|
|
|
cardiac muscle cell proliferation
|
GO:0060038 |
6 |
0.096
|
|
|
|
positive regulation of mrna 3 end processing
|
GO:0031442 |
12 |
0.095
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
140 |
0.095
|
|
|
|
developmental growth
|
GO:0048589 |
48 |
0.093
|
|
|
|
glandular epithelial cell development
|
GO:0002068 |
5 |
0.093
|
|
|
|
histone ubiquitination
|
GO:0016574 |
31 |
0.093
|
|
|
|
rhythmic process
|
GO:0048511 |
31 |
0.093
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.093
|
Yeast |
|
|
maintenance of location
|
GO:0051235 |
112 |
0.092
|
|
|
|
germ cell development
|
GO:0007281 |
8 |
0.092
|
|
|
|
spermatogenesis
|
GO:0007283 |
22 |
0.091
|
|
|
|
lung epithelial cell differentiation
|
GO:0060487 |
1 |
0.091
|
|
|
|
pattern specification process
|
GO:0007389 |
43 |
0.091
|
|
|
|
negative regulation of meiotic cell cycle
|
GO:0051447 |
2 |
0.090
|
Yeast |
|
|
regulation of protein dephosphorylation
|
GO:0035304 |
18 |
0.089
|
|
|
|
hepaticobiliary system development
|
GO:0061008 |
10 |
0.089
|
|
|
|
response to decreased oxygen levels
|
GO:0036293 |
96 |
0.088
|
|
|
|
negative regulation of protein complex disassembly
|
GO:0043242 |
20 |
0.088
|
|
|
|
reproductive system development
|
GO:0061458 |
56 |
0.087
|
|
|
|
regulation of cell diameter
|
GO:0060305 |
1 |
0.086
|
|
