Homo sapiens

0 known processes

TIMP2

TIMP metallopeptidase inhibitor 2

(Aliases: CSC-21K)

TIMP2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
collagen catabolic process GO:0030574 10 0.950
vasculature development GO:0001944 181 0.848
neuron projection regeneration GO:0031102 1 0.787
regulation of cell migration GO:0030334 289 0.727
Human
blood vessel development GO:0001568 172 0.725
negative regulation of hydrogen peroxide metabolic process GO:0010727 3 0.664
regulation of cellular component movement GO:0051270 334 0.579
Human
multicellular organismal catabolic process GO:0044243 12 0.522
glial cell migration GO:0008347 4 0.517
regulation of locomotion GO:0040012 329 0.455
Human
cellular response to endogenous stimulus GO:0071495 336 0.431
blood vessel maturation GO:0001955 1 0.430
circulatory system development GO:0072359 262 0.429
endothelial cell proliferation GO:0001935 65 0.426
protein processing GO:0016485 226 0.423
Human Mouse
response to oxidative stress GO:0006979 121 0.408
protein maturation GO:0051604 233 0.390
Human Mouse
blood vessel morphogenesis GO:0048514 162 0.364
positive regulation of cell motility GO:2000147 177 0.338
positive regulation of keratinocyte migration GO:0051549 4 0.328
cardiovascular system development GO:0072358 262 0.310
bone trabecula formation GO:0060346 1 0.309
multicellular organismal metabolic process GO:0044236 34 0.304
membrane organization GO:0061024 292 0.301
cellular response to growth factor stimulus GO:0071363 197 0.296
angiogenesis GO:0001525 147 0.294
anatomical structure formation involved in morphogenesis GO:0048646 284 0.271
regulation of cell motility GO:2000145 299 0.270
Human
epithelium development GO:0060429 227 0.261
axon regeneration GO:0031103 1 0.257
trabecula morphogenesis GO:0061383 2 0.253
endothelial cell migration GO:0043542 86 0.251
cell development GO:0048468 328 0.239
Mouse
regulation of peptidase activity GO:0052547 180 0.233
Human Mouse
regulation of keratinocyte migration GO:0051547 4 0.227
cell adhesion GO:0007155 325 0.223
ovarian follicle development GO:0001541 5 0.221
hydrogen peroxide metabolic process GO:0042743 20 0.215
prostate gland morphogenesis GO:0060512 1 0.214
response to axon injury GO:0048678 1 0.212
negative regulation of cell adhesion GO:0007162 64 0.212
craniofacial suture morphogenesis GO:0097094 3 0.208
regeneration GO:0031099 4 0.205
positive regulation of cellular component movement GO:0051272 181 0.199
regulation of cellular response to growth factor stimulus GO:0090287 76 0.197
response to hyperoxia GO:0055093 4 0.197
positive regulation of cell migration GO:0030335 172 0.193
regulation of cellular amine metabolic process GO:0033238 11 0.189
biological adhesion GO:0022610 331 0.186
negative regulation of hydrolase activity GO:0051346 182 0.184
Human Mouse
cellular ketone metabolic process GO:0042180 80 0.170
regulation of cell adhesion GO:0030155 166 0.166
defense response GO:0006952 315 0.160
prostate gland development GO:0030850 3 0.158
response to wounding GO:0009611 168 0.156
response to other organism GO:0051707 261 0.148
endoderm development GO:0007492 33 0.145
cellular component morphogenesis GO:0032989 314 0.143
cell projection organization GO:0030030 252 0.139
cytokine production GO:0001816 247 0.137
luteinization GO:0001553 2 0.133
bone trabecula morphogenesis GO:0061430 1 0.132
regulation of epithelial cell proliferation GO:0050678 113 0.132
female gamete generation GO:0007292 2 0.132
negative regulation of cellular component organization GO:0051129 235 0.132
endochondral bone morphogenesis GO:0060350 3 0.131
negative regulation of cellular protein metabolic process GO:0032269 353 0.129
Human Mouse
negative regulation of cellular component movement GO:0051271 106 0.125
Human
response to hydrogen peroxide GO:0042542 40 0.123
enzyme linked receptor protein signaling pathway GO:0007167 303 0.121
response to lipid GO:0033993 206 0.120
response to activity GO:0014823 0 0.120
positive regulation of locomotion GO:0040017 186 0.118
organ morphogenesis GO:0009887 147 0.116
multicellular organismal aging GO:0010259 3 0.116
negative regulation of endopeptidase activity GO:0010951 84 0.115
Human Mouse
negative regulation of developmental process GO:0051093 247 0.114
Human
regulation of ion transmembrane transporter activity GO:0032412 72 0.112
response to growth factor GO:0070848 205 0.110
negative regulation of proteolysis GO:0045861 132 0.110
Human Mouse
protein oligomerization GO:0051259 173 0.110
taxis GO:0042330 157 0.109
morphogenesis of a branching structure GO:0001763 21 0.109
cell matrix adhesion GO:0007160 85 0.108
determination of adult lifespan GO:0008340 2 0.107
response to increased oxygen levels GO:0036296 4 0.107
regulation of vasculature development GO:1901342 97 0.106
regulation of blood vessel size GO:0050880 18 0.105
reactive oxygen species metabolic process GO:0072593 75 0.104
regulation of angiogenesis GO:0045765 92 0.103
response to hypoxia GO:0001666 96 0.103
cellular response to xenobiotic stimulus GO:0071466 29 0.102
ovulation cycle process GO:0022602 9 0.100
cell morphogenesis involved in differentiation GO:0000904 144 0.097
cellular response to organic cyclic compound GO:0071407 127 0.097
multicellular organismal macromolecule metabolic process GO:0044259 29 0.097
negative regulation of vasculature development GO:1901343 43 0.094
cell morphogenesis GO:0000902 296 0.092
epithelium migration GO:0090132 119 0.091
regulation of protein maturation GO:1903317 150 0.091
Human Mouse
anterior posterior axis specification GO:0009948 2 0.090
response to estrogen GO:0043627 47 0.090
response to electrical stimulus GO:0051602 1 0.090
response to xenobiotic stimulus GO:0009410 30 0.089
response to reactive oxygen species GO:0000302 61 0.088
cell substrate adhesion GO:0031589 132 0.088
negative regulation of protein maturation GO:1903318 142 0.088
Human Mouse
cellular response to hormone stimulus GO:0032870 125 0.087
endoderm formation GO:0001706 33 0.087
innate immune response GO:0045087 178 0.087
positive regulation of immune response GO:0050778 159 0.087
regulation of transmembrane transport GO:0034762 139 0.086
vascular process in circulatory system GO:0003018 29 0.086
response to abiotic stimulus GO:0009628 336 0.086
regulation of endothelial cell migration GO:0010594 67 0.086
regulation of ion transport GO:0043269 189 0.086
negative regulation of peptidase activity GO:0010466 91 0.084
Human Mouse
ossification GO:0001503 121 0.082
positive regulation of protein phosphorylation GO:0001934 313 0.081
regulation of protein complex assembly GO:0043254 147 0.080
positive regulation of defense response GO:0031349 87 0.080
negative regulation of fibroblast growth factor receptor signaling pathway GO:0040037 2 0.080
regulation of reactive oxygen species metabolic process GO:2000377 41 0.080
positive regulation of cell proliferation GO:0008284 301 0.080
Human
response to steroid hormone GO:0048545 80 0.078
retina layer formation GO:0010842 3 0.076
parturition GO:0007567 1 0.075
actin filament based process GO:0030029 224 0.075
post embryonic development GO:0009791 2 0.075
regulation of anatomical structure morphogenesis GO:0022603 286 0.074
response to organonitrogen compound GO:0010243 156 0.074
cell chemotaxis GO:0060326 112 0.074
response to hormone GO:0009725 175 0.073
negative regulation of cell motility GO:2000146 104 0.072
Human
response to cytokine GO:0034097 232 0.071
response to biotic stimulus GO:0009607 276 0.071
response to organic cyclic compound GO:0014070 204 0.071
endochondral ossification GO:0001958 1 0.070
regulation of cellular component biogenesis GO:0044087 281 0.070
negative regulation of cell migration GO:0030336 102 0.069
Human
collagen metabolic process GO:0032963 28 0.069
cell migration involved in gastrulation GO:0042074 1 0.068
system process GO:0003008 349 0.068
chemotaxis GO:0006935 157 0.068
cellular response to fluid shear stress GO:0071498 7 0.068
zymogen activation GO:0031638 70 0.066
negative regulation of locomotion GO:0040013 118 0.066
Human
response to oxygen containing compound GO:1901700 369 0.065
nervous system development GO:0007399 293 0.063
Mouse
tissue morphogenesis GO:0048729 96 0.063
regulation of leukocyte migration GO:0002685 63 0.063
circulatory system process GO:0003013 113 0.062
vesicle mediated transport GO:0016192 371 0.062
regulation of system process GO:0044057 101 0.062
regulation of transporter activity GO:0032409 82 0.061
response to mechanical stimulus GO:0009612 51 0.061
negative regulation of protein processing GO:0010955 142 0.061
Human Mouse
regulation of response to external stimulus GO:0032101 222 0.060
cellular amino acid metabolic process GO:0006520 116 0.059
response to decreased oxygen levels GO:0036293 96 0.058
immune response GO:0006955 307 0.057
organic hydroxy compound metabolic process GO:1901615 147 0.057
negative regulation of cellular response to growth factor stimulus GO:0090288 41 0.057
endodermal cell differentiation GO:0035987 31 0.057
regulation of endothelial cell proliferation GO:0001936 56 0.056
regulation of transmembrane transporter activity GO:0022898 74 0.055
regulation of innate immune response GO:0045088 97 0.055
morphogenesis of an epithelium GO:0002009 60 0.054
regulation of defense response GO:0031347 154 0.053
actin cytoskeleton organization GO:0030036 207 0.053
positive regulation of map kinase activity GO:0043406 80 0.052
transmembrane transport GO:0055085 399 0.052
ovulation cycle GO:0042698 9 0.052
regulation of cell differentiation GO:0045595 393 0.052
Mouse
negative regulation of transport GO:0051051 176 0.052
apoptotic signaling pathway GO:0097190 268 0.052
ion transmembrane transport GO:0034220 338 0.051
regulation of ion transmembrane transport GO:0034765 132 0.051
response to inorganic substance GO:0010035 127 0.051
cellular response to fibroblast growth factor stimulus GO:0044344 39 0.051
regulation of immune response GO:0050776 201 0.050
positive regulation of programmed cell death GO:0043068 249 0.050
response to oxygen levels GO:0070482 100 0.050
regulation of endopeptidase activity GO:0052548 170 0.049
Human Mouse
regulation of transforming growth factor beta receptor signaling pathway GO:0017015 48 0.049
positive regulation of epithelial cell migration GO:0010634 55 0.049
positive regulation of immune system process GO:0002684 283 0.049
negative regulation of transporter activity GO:0032410 25 0.048
ribonucleoside catabolic process GO:0042454 406 0.048
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.047
regulation of protein binding GO:0043393 66 0.047
regulation of protein oligomerization GO:0032459 26 0.046
cellular response to steroid hormone stimulus GO:0071383 37 0.046
positive regulation of angiogenesis GO:0045766 51 0.046
positive regulation of phosphorylation GO:0042327 394 0.045
cell projection morphogenesis GO:0048858 129 0.045
digestive tract development GO:0048565 75 0.044
positive regulation of cellular component biogenesis GO:0044089 158 0.044
negative regulation of ion transmembrane transport GO:0034766 26 0.044
negative regulation of blood vessel morphogenesis GO:2000181 41 0.044
skeletal system development GO:0001501 79 0.044
epithelial cell migration GO:0010631 119 0.044
establishment of planar polarity GO:0001736 3 0.044
anatomical structure homeostasis GO:0060249 100 0.043
negative regulation of cell substrate adhesion GO:0010812 24 0.043
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 90 0.043
positive regulation of hydrolase activity GO:0051345 331 0.043
positive regulation of binding GO:0051099 45 0.042
epithelial cell differentiation GO:0030855 141 0.042
female gonad development GO:0008585 10 0.042
mesenchyme development GO:0060485 59 0.042
blood circulation GO:0008015 113 0.041
positive regulation of endothelial cell migration GO:0010595 39 0.041
epithelial cell proliferation GO:0050673 128 0.041
organic hydroxy compound transport GO:0015850 63 0.041
positive regulation of transferase activity GO:0051347 227 0.041
ameboidal type cell migration GO:0001667 135 0.041
Human
regulation of cation channel activity GO:2001257 33 0.040
cell part morphogenesis GO:0032990 137 0.040
positive regulation of proteolysis GO:0045862 142 0.040
single organism membrane organization GO:0044802 268 0.039
rhythmic process GO:0048511 31 0.039
tissue regeneration GO:0042246 3 0.039
neurogenesis GO:0022008 169 0.039
Mouse
cytoplasmic transport GO:0016482 379 0.039
maintenance of location GO:0051235 112 0.039
hematopoietic or lymphoid organ development GO:0048534 186 0.038
cellular response to acid chemical GO:0071229 44 0.038
regulation of binding GO:0051098 111 0.038
convergent extension GO:0060026 1 0.038
gastrulation GO:0007369 51 0.038
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.038
negative regulation of transmembrane transport GO:0034763 29 0.037
gland development GO:0048732 48 0.037
cellular response to alcohol GO:0097306 29 0.037
connective tissue development GO:0061448 39 0.037
regulation of growth GO:0040008 165 0.035
intracellular protein transport GO:0006886 270 0.035
negative regulation of immune system process GO:0002683 136 0.035
cellular response to hydrogen peroxide GO:0070301 37 0.034
positive regulation of innate immune response GO:0045089 79 0.034
positive regulation of cellular component organization GO:0051130 376 0.034
urogenital system development GO:0001655 65 0.034
action potential GO:0001508 34 0.034
locomotory behavior GO:0007626 1 0.034
blastoderm segmentation GO:0007350 2 0.033
regulation of secretion GO:0051046 194 0.033
skin development GO:0043588 76 0.033
response to external biotic stimulus GO:0043207 261 0.033
keratinocyte migration GO:0051546 6 0.033
lipid transport GO:0006869 90 0.033
cellular lipid catabolic process GO:0044242 65 0.033
positive regulation of apoptotic process GO:0043065 246 0.032
neurological system process GO:0050877 163 0.032
developmental process involved in reproduction GO:0003006 66 0.032
regulation of cell morphogenesis GO:0022604 153 0.032
regulation of tube size GO:0035150 18 0.031
tissue remodeling GO:0048771 16 0.031
regulation of systemic arterial blood pressure by circulatory renin angiotensin GO:0001991 4 0.031
positive regulation of fibroblast migration GO:0010763 3 0.031
regulation of blood circulation GO:1903522 59 0.031
protein homooligomerization GO:0051260 100 0.031
single organism reproductive process GO:0044702 98 0.031
Human
rho protein signal transduction GO:0007266 26 0.031
response to alkaloid GO:0043279 20 0.031
regulation of cell growth GO:0001558 135 0.030
mapk cascade GO:0000165 288 0.030
Mouse
reproductive process GO:0022414 106 0.030
Human
negative regulation of blood circulation GO:1903523 4 0.030
positive regulation of lymphocyte activation GO:0051251 73 0.030
regulation of cellular amino acid metabolic process GO:0006521 6 0.030
leukocyte migration GO:0050900 107 0.030
positive regulation of mapk cascade GO:0043410 190 0.029
fibroblast growth factor receptor signaling pathway GO:0008543 26 0.029
endocytosis GO:0006897 159 0.029
positive regulation of developmental process GO:0051094 314 0.029
regulation of nucleotide metabolic process GO:0006140 269 0.028
Mouse
oogenesis GO:0048477 2 0.028
regulation of focal adhesion assembly GO:0051893 20 0.028
nucleoside catabolic process GO:0009164 408 0.028
neural crest cell development GO:0014032 3 0.028
cellular response to lipid GO:0071396 127 0.028
sprouting angiogenesis GO:0002040 29 0.028
receptor metabolic process GO:0043112 81 0.028
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.027
nuclear transport GO:0051169 179 0.027
amine metabolic process GO:0009308 44 0.027
regulation of hormone levels GO:0010817 125 0.027
response to fluid shear stress GO:0034405 14 0.027
cellular amine metabolic process GO:0044106 41 0.027
cellular response to transforming growth factor beta stimulus GO:0071560 94 0.027
female pregnancy GO:0007565 17 0.026
Human
regulation of epithelial cell migration GO:0010632 93 0.026
regulation of actin filament based process GO:0032970 141 0.026
carbohydrate metabolic process GO:0005975 207 0.026
male sex differentiation GO:0046661 25 0.026
neuron differentiation GO:0030182 138 0.026
Mouse
positive regulation of cell death GO:0010942 263 0.026
retina vasculature morphogenesis in camera type eye GO:0061299 3 0.026
immune system development GO:0002520 195 0.026
positive regulation of cytokine production GO:0001819 167 0.026
neuron development GO:0048666 113 0.026
regulation of leukocyte activation GO:0002694 115 0.025
response to nitrogen compound GO:1901698 184 0.025
negative regulation of response to external stimulus GO:0032102 83 0.025
negative regulation of cytokine production GO:0001818 82 0.025
negative regulation of focal adhesion assembly GO:0051895 5 0.025
regulation of proteolysis GO:0030162 293 0.025
Human Mouse
positive regulation of peptidase activity GO:0010952 88 0.025
inflammatory response GO:0006954 79 0.025
trabecula formation GO:0060343 1 0.025
bone development GO:0060348 26 0.025
formation of primary germ layer GO:0001704 42 0.025
response to acid chemical GO:0001101 66 0.025
positive regulation of kinase activity GO:0033674 204 0.024
regulation of cytokine production GO:0001817 232 0.024
cellular response to reactive oxygen species GO:0034614 50 0.024
negative regulation of apoptotic process GO:0043066 316 0.024
membrane protein proteolysis GO:0033619 38 0.024
Human
response to drug GO:0042493 81 0.024
negative regulation of response to wounding GO:1903035 47 0.024
regulation of purine nucleotide metabolic process GO:1900542 264 0.024
Mouse
replacement ossification GO:0036075 1 0.024
response to fibroblast growth factor GO:0071774 39 0.024
convergent extension involved in gastrulation GO:0060027 1 0.024
reproductive system development GO:0061458 56 0.024
cell activation GO:0001775 213 0.023
positive regulation of transport GO:0051050 336 0.023
embryonic morphogenesis GO:0048598 85 0.023
positive regulation of cell differentiation GO:0045597 211 0.023
protein catabolic process GO:0030163 325 0.023
Human
lipid catabolic process GO:0016042 84 0.023
autophagy GO:0006914 88 0.022
development of primary female sexual characteristics GO:0046545 10 0.022
lipid localization GO:0010876 106 0.022
positive regulation of cellular catabolic process GO:0031331 284 0.022
cell junction organization GO:0034330 79 0.022
regulation of transferase activity GO:0051338 355 0.022
regulation of intracellular transport GO:0032386 195 0.022
chondrocyte proliferation GO:0035988 4 0.022
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.022
reproductive structure development GO:0048608 55 0.022
stem cell development GO:0048864 69 0.022
response to nicotine GO:0035094 12 0.022
cellular response to oxidative stress GO:0034599 85 0.022
anterior posterior axis specification embryo GO:0008595 2 0.022
purine containing compound catabolic process GO:0072523 411 0.022
negative regulation of epithelial cell migration GO:0010633 38 0.021
single organism carbohydrate metabolic process GO:0044723 193 0.021
positive regulation of nucleoside metabolic process GO:0045979 186 0.021
embryonic organ morphogenesis GO:0048562 24 0.021
growth GO:0040007 202 0.021
basement membrane organization GO:0071711 3 0.021
membrane lipid metabolic process GO:0006643 53 0.021
axonogenesis GO:0007409 31 0.021
tube morphogenesis GO:0035239 95 0.021
regulation of apoptotic signaling pathway GO:2001233 175 0.021
developmental maturation GO:0021700 28 0.021
positive regulation of protein complex assembly GO:0031334 86 0.021
regulation of cellular ketone metabolic process GO:0010565 50 0.021
nerve development GO:0021675 4 0.020
anatomical structure maturation GO:0071695 9 0.020
regulation of anatomical structure size GO:0090066 101 0.020
regulation of cell development GO:0060284 161 0.020
Mouse
wound healing GO:0042060 115 0.020
protein tetramerization GO:0051262 47 0.020
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.020
regulation of kinase activity GO:0043549 314 0.020
lipid metabolic process GO:0006629 381 0.020
embryo development GO:0009790 123 0.020
negative regulation of ion transmembrane transporter activity GO:0032413 19 0.020
protein localization to membrane GO:0072657 160 0.020
protein targeting GO:0006605 187 0.020
neuromuscular process GO:0050905 15 0.020
face development GO:0060324 12 0.019
regulation of establishment of protein localization GO:0070201 242 0.019
negative regulation of organelle organization GO:0010639 126 0.019
cellular response to estrogen stimulus GO:0071391 16 0.019
epithelial tube morphogenesis GO:0060562 38 0.019
posttranscriptional regulation of gene expression GO:0010608 213 0.019
positive regulation of ras gtpase activity GO:0032320 117 0.019
signal transduction by phosphorylation GO:0023014 297 0.019
Mouse
hormone metabolic process GO:0042445 61 0.019
cellular macromolecule catabolic process GO:0044265 380 0.019
cell morphogenesis involved in neuron differentiation GO:0048667 44 0.019
granulocyte chemotaxis GO:0071621 37 0.019
single organism cellular localization GO:1902580 332 0.019
response to transforming growth factor beta GO:0071559 94 0.019
organophosphate catabolic process GO:0046434 430 0.019
positive regulation of gtpase activity GO:0043547 166 0.018
positive regulation of catabolic process GO:0009896 310 0.018
peptide metabolic process GO:0006518 51 0.018
negative regulation of catabolic process GO:0009895 104 0.018
Human
motor neuron axon guidance GO:0008045 2 0.018
regulation of protein localization GO:0032880 296 0.018
multicellular organismal homeostasis GO:0048871 67 0.018
cell cell junction organization GO:0045216 69 0.018
organophosphate biosynthetic process GO:0090407 163 0.018
alcohol metabolic process GO:0006066 114 0.018
leukocyte chemotaxis GO:0030595 76 0.018
regulation of multicellular organismal metabolic process GO:0044246 17 0.018
regulation of blood vessel remodeling GO:0060312 2 0.017
regulation of cytoskeleton organization GO:0051493 177 0.017
response to metal ion GO:0010038 84 0.017
leukocyte mediated immunity GO:0002443 59 0.017
small molecule biosynthetic process GO:0044283 157 0.017
sex differentiation GO:0007548 45 0.017
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090100 41 0.017
head development GO:0060322 108 0.017
digestive system development GO:0055123 75 0.017
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 43 0.017
aging GO:0007568 66 0.017
negative regulation of trophoblast cell migration GO:1901164 3 0.017
Human
positive regulation of organelle organization GO:0010638 195 0.016
positive regulation of nucleotide catabolic process GO:0030813 185 0.016
regulation of protein kinase activity GO:0045859 289 0.016
reproduction GO:0000003 63 0.016
actin filament organization GO:0007015 128 0.016
myeloid cell differentiation GO:0030099 117 0.016
nucleoside phosphate catabolic process GO:1901292 412 0.016
neuron projection morphogenesis GO:0048812 50 0.016
nucleoside triphosphate catabolic process GO:0009143 394 0.016
single organism membrane fusion GO:0044801 37 0.016
regulation of macrophage chemotaxis GO:0010758 4 0.016
regulation of blood coagulation GO:0030193 42 0.016
regulation of wnt signaling pathway GO:0030111 123 0.016
regulation of oxidative stress induced cell death GO:1903201 24 0.016
embryonic viscerocranium morphogenesis GO:0048703 1 0.016
negative regulation of immune effector process GO:0002698 38 0.016
negative regulation of angiogenesis GO:0016525 39 0.015
vasoconstriction GO:0042310 11 0.015
cell junction assembly GO:0034329 67 0.015
cellular response to oxygen containing compound GO:1901701 276 0.015
mitochondrion organization GO:0007005 156 0.015
regulation of cytoplasmic transport GO:1903649 149 0.015
multicellular organismal signaling GO:0035637 34 0.015
regulation of protein catabolic process GO:0042176 155 0.015
Human
cell growth GO:0016049 160 0.015
tube development GO:0035295 125 0.015
morphogenesis of a polarized epithelium GO:0001738 3 0.015
male gonad development GO:0008584 23 0.015
regulation of protein serine threonine kinase activity GO:0071900 179 0.015
gtp metabolic process GO:0046039 239 0.015
segmentation GO:0035282 4 0.015
negative regulation of synaptic transmission GO:0050805 2 0.015
focal adhesion assembly GO:0048041 30 0.015
retina development in camera type eye GO:0060041 15 0.015
mitotic cell cycle GO:0000278 326 0.014
purine nucleoside catabolic process GO:0006152 398 0.014
tripartite regional subdivision GO:0007351 2 0.014
endothelial cell cell adhesion GO:0071603 1 0.014
regulation of cysteine type endopeptidase activity GO:2000116 127 0.014
adherens junction organization GO:0034332 36 0.014
purine nucleotide catabolic process GO:0006195 405 0.014
negative regulation of cellular catabolic process GO:0031330 83 0.014
Human
regulation of gtp catabolic process GO:0033124 180 0.014
cellular response to thyroid hormone stimulus GO:0097067 9 0.014
inner ear morphogenesis GO:0042472 4 0.014
xenobiotic metabolic process GO:0006805 28 0.014
regulation of leukocyte differentiation GO:1902105 61 0.014
positive regulation of cellular amine metabolic process GO:0033240 7 0.014
cellular response to amino acid stimulus GO:0071230 12 0.014
negative regulation of cell differentiation GO:0045596 171 0.014
plasma membrane organization GO:0007009 115 0.014
adenylate cyclase inhibiting g protein coupled receptor signaling pathway GO:0007193 22 0.014
regulation of ras protein signal transduction GO:0046578 155 0.014
bone morphogenesis GO:0060349 10 0.013
negative regulation of ion transport GO:0043271 39 0.013
macrophage chemotaxis GO:0048246 10 0.013
regulation of adherens junction organization GO:1903391 21 0.013
multicellular organismal response to stress GO:0033555 1 0.013
ribonucleotide catabolic process GO:0009261 405 0.013
protein import GO:0017038 130 0.013
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.013
embryonic camera type eye morphogenesis GO:0048596 2 0.013
cholesterol transport GO:0030301 39 0.013

TIMP2 disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 295 0.844
inherited metabolic disorder DOID:655 242 0.844
lysosomal storage disease DOID:3211 47 0.349
central nervous system disease DOID:331 186 0.113
nervous system disease DOID:863 431 0.113
lipid storage disease DOID:9455 28 0.108
sensory system disease DOID:0050155 203 0.036
eye and adnexa disease DOID:1492 150 0.036
eye disease DOID:5614 149 0.036
cerebral degeneration DOID:1443 16 0.035
brain disease DOID:936 73 0.035
musculoskeletal system disease DOID:17 223 0.032
retinal disease DOID:5679 118 0.021
immune system disease DOID:2914 155 0.021
connective tissue disease DOID:65 109 0.017
retinal degeneration DOID:8466 89 0.016
bone development disease DOID:0080006 55 0.015
bone disease DOID:0080001 88 0.015
sphingolipidosis DOID:1927 14 0.013