IMP

Process View

Homo sapiens

3 genes annotated in human

negative regulation of hydrogen peroxide metabolic process

Any process that decreases the frequency, rate or extent of the chemical reactions and pathways involving hydrogen peroxide.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "negative regulation of hydrogen peroxide metabolic process"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "negative regulation of hydrogen peroxide metabolic process" (in gray)

Name	Description	Probability	Func Analog Organism
APOE	apolipoprotein E	0.854
MMP12	matrix metallopeptidase 12 (macrophage elastase)	0.845
CAPN1	calpain 1, (mu/I) large subunit	0.798
TIMP2	TIMP metallopeptidase inhibitor 2	0.664
THBS1	thrombospondin 1	0.589
GLRX	glutaredoxin (thioltransferase)	0.431
MMP14	matrix metallopeptidase 14 (membrane-inserted)	0.389
MMP10	matrix metallopeptidase 10 (stromelysin 2)	0.371	Human
MMP3	matrix metallopeptidase 3 (stromelysin 1, progelatinase)	0.358
TGFB1	transforming growth factor, beta 1	0.250
A2M	alpha-2-macroglobulin	0.234
MMP1	matrix metallopeptidase 1 (interstitial collagenase)	0.222	Human
APOA1	apolipoprotein A-I	0.205
CCL7	chemokine (C-C motif) ligand 7	0.167
THBS2	thrombospondin 2	0.165
MMP13	matrix metallopeptidase 13 (collagenase 3)	0.141	Human
JAK1	Janus kinase 1	0.091
ITGA2	integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)	0.090
JAK2	Janus kinase 2	0.088
INHBA	inhibin, beta A	0.076
TIMP1	TIMP metallopeptidase inhibitor 1	0.070
IL6ST	interleukin 6 signal transducer (gp130, oncostatin M receptor)	0.067
MEP1A	meprin A, alpha (PABA peptide hydrolase)	0.066
CXCL5	chemokine (C-X-C motif) ligand 5	0.062
CXCL6	chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2)	0.062
LRRC15	leucine rich repeat containing 15	0.058
PIAS3	protein inhibitor of activated STAT, 3	0.057
APOC1	apolipoprotein C-I	0.050
PDPN	podoplanin	0.050
SLC11A1	solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1	0.050
DOK4	docking protein 4	0.047
IFNAR2	interferon (alpha, beta and omega) receptor 2	0.046
CORO1A	coronin, actin binding protein, 1A	0.042
MMP11	matrix metallopeptidase 11 (stromelysin 3)	0.040	Human
NCF1	neutrophil cytosolic factor 1	0.038
CHI3L1	chitinase 3-like 1 (cartilage glycoprotein-39)	0.035
LAMC2	laminin, gamma 2	0.034
FAP	fibroblast activation protein, alpha	0.033
PTHLH	parathyroid hormone-like hormone	0.033
HPR	haptoglobin-related protein	0.032
PTAFR	platelet-activating factor receptor	0.031
BGN	biglycan	0.029
BMP1	bone morphogenetic protein 1	0.029
TGFBR2	transforming growth factor, beta receptor II (70/80kDa)	0.029
CSF3R	colony stimulating factor 3 receptor (granulocyte)	0.028
SPP1	secreted phosphoprotein 1	0.027
POSTN	periostin, osteoblast specific factor	0.027
STC1	stanniocalcin 1	0.027
OSBPL10	oxysterol binding protein-like 10	0.027
MMP8	matrix metallopeptidase 8 (neutrophil collagenase)	0.026	Human
TNFAIP6	tumor necrosis factor, alpha-induced protein 6	0.026
COL10A1	collagen, type X, alpha 1	0.025
CCL20	chemokine (C-C motif) ligand 20	0.025
SERPINB2	serpin peptidase inhibitor, clade B (ovalbumin), member 2	0.025
MSC	musculin	0.024
PRKACA	protein kinase, cAMP-dependent, catalytic, alpha	0.023
KCNJ15	potassium inwardly-rectifying channel, subfamily J, member 15	0.023
RPS3	ribosomal protein S3	0.021
MEP1B	meprin A, beta	0.021
MMP9	matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)	0.021	Human
SERPINA3	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3	0.020
LBP	lipopolysaccharide binding protein	0.020
PI3	peptidase inhibitor 3, skin-derived	0.020
WISP1	WNT1 inducible signaling pathway protein 1	0.019
SEMA7A	semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group)	0.019
SOCS1	suppressor of cytokine signaling 1	0.019
MFGE8	milk fat globule-EGF factor 8 protein	0.018
TNFRSF10C	tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain	0.018
S100A2	S100 calcium binding protein A2	0.018
ELN	elastin	0.018
RETN	resistin	0.018
MMP19	matrix metallopeptidase 19	0.017	Human
MMP2	matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)	0.017	Human
KRT16	keratin 16	0.017
ADAM12	ADAM metallopeptidase domain 12	0.016
SETD7	SET domain containing (lysine methyltransferase) 7	0.016
IL1R2	interleukin 1 receptor, type II	0.016
CSF2	colony stimulating factor 2 (granulocyte-macrophage)	0.016
CCL11	chemokine (C-C motif) ligand 11	0.015
TIRAP	toll-interleukin 1 receptor (TIR) domain containing adaptor protein	0.015
ECM1	extracellular matrix protein 1	0.015
FOLR3	folate receptor 3 (gamma)	0.015
AKAP8L	A kinase (PRKA) anchor protein 8-like	0.015
CASP10	caspase 10, apoptosis-related cysteine peptidase	0.015
WNT2	wingless-type MMTV integration site family member 2	0.015
CAPN2	calpain 2, (m/II) large subunit	0.014
FGD1	FYVE, RhoGEF and PH domain containing 1	0.014
SEMA3F	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F	0.014
MMP7	matrix metallopeptidase 7 (matrilysin, uterine)	0.014	Human
IL11	interleukin 11	0.014
STAT5A	signal transducer and activator of transcription 5A	0.014
TNS3	tensin 3	0.014
PTGES	prostaglandin E synthase	0.014
APOA2	apolipoprotein A-II	0.013
COMP	cartilage oligomeric matrix protein	0.013
ESM1	endothelial cell-specific molecule 1	0.013
CXCL13	chemokine (C-X-C motif) ligand 13	0.013
CEACAM8	carcinoembryonic antigen-related cell adhesion molecule 8	0.013
CLEC4E	C-type lectin domain family 4, member E	0.013
EPHB2	EPH receptor B2	0.013
SAA2	serum amyloid A2	0.012
DEFA4	defensin, alpha 4, corticostatin	0.012
LAMC3	laminin, gamma 3	0.012
SIAH2	seven in absentia homolog 2 (Drosophila)	0.012
IBSP	integrin-binding sialoprotein	0.012
SMO	smoothened homolog (Drosophila)	0.012
ACPP	acid phosphatase, prostate	0.012
BPI	bactericidal/permeability-increasing protein	0.012
IL13RA2	interleukin 13 receptor, alpha 2	0.012
MPO	myeloperoxidase	0.012
OLR1	oxidized low density lipoprotein (lectin-like) receptor 1	0.012
LILRA3	leukocyte immunoglobulin-like receptor, subfamily A (without TM domain), member 3	0.012
CAMP	cathelicidin antimicrobial peptide	0.012
EGF	epidermal growth factor	0.012
CP	ceruloplasmin (ferroxidase)	0.012
LMO2	LIM domain only 2 (rhombotin-like 1)	0.012
VAV2	vav 2 guanine nucleotide exchange factor	0.011
CCL22	chemokine (C-C motif) ligand 22	0.011
CSF3	colony stimulating factor 3 (granulocyte)	0.011
LOXL2	lysyl oxidase-like 2	0.011
PLAU	plasminogen activator, urokinase	0.011
DOK6	docking protein 6	0.011
PLAUR	plasminogen activator, urokinase receptor	0.011
STAT2	signal transducer and activator of transcription 2, 113kDa	0.011
HP	haptoglobin	0.011
WNT4	wingless-type MMTV integration site family, member 4	0.011
MDM2	Mdm2 p53 binding protein homolog (mouse)	0.011
PRTN3	proteinase 3	0.011
MARCO	macrophage receptor with collagenous structure	0.011
SH2D1B	SH2 domain containing 1B	0.011
FFAR2	free fatty acid receptor 2	0.011
BCAN	brevican	0.011
AQP9	aquaporin 9	0.010
LAMB3	laminin, beta 3	0.010
IFNGR1	interferon gamma receptor 1	0.010
THY1	Thy-1 cell surface antigen	0.010
CCL18	chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)	0.010
ITGB3	integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)	0.010
CST1	cystatin SN	0.010
SLCO1B3	solute carrier organic anion transporter family, member 1B3	0.010