|
|
protein deubiquitination
|
GO:0016579 |
79 |
0.989
|
|
|
|
protein modification by small protein removal
|
GO:0070646 |
92 |
0.944
|
|
|
|
protein ubiquitination
|
GO:0016567 |
314 |
0.789
|
Human |
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
380 |
0.730
|
Human |
|
|
protein k63 linked deubiquitination
|
GO:0070536 |
21 |
0.721
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.560
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
244 |
0.517
|
Human |
|
|
modification dependent protein catabolic process
|
GO:0019941 |
209 |
0.515
|
Human |
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
85 |
0.465
|
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
166 |
0.411
|
|
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
212 |
0.398
|
Human |
|
|
protein modification by small protein conjugation
|
GO:0032446 |
342 |
0.397
|
Human |
|
|
positive regulation of immune system process
|
GO:0002684 |
283 |
0.372
|
|
|
|
cellular component disassembly
|
GO:0022411 |
92 |
0.360
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.360
|
|
|
|
immune system development
|
GO:0002520 |
195 |
0.359
|
|
|
|
mapk cascade
|
GO:0000165 |
288 |
0.356
|
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
97 |
0.348
|
|
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.340
|
|
|
|
protein k48 linked deubiquitination
|
GO:0071108 |
19 |
0.339
|
|
|
|
regulation of i kappab kinase nf kappab signaling
|
GO:0043122 |
162 |
0.337
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.279
|
|
|
|
positive regulation of i kappab kinase nf kappab signaling
|
GO:0043123 |
132 |
0.278
|
|
|
|
protein polyubiquitination
|
GO:0000209 |
110 |
0.273
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.272
|
|
|
|
negative regulation of extrinsic apoptotic signaling pathway
|
GO:2001237 |
52 |
0.260
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
119 |
0.258
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.252
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.241
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.226
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.224
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
175 |
0.223
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
232 |
0.219
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.208
|
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
206 |
0.203
|
Human |
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.202
|
|
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.199
|
Human |
|
|
innate immune response
|
GO:0045087 |
178 |
0.197
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.196
|
|
|
|
chromatin organization
|
GO:0006325 |
351 |
0.191
|
|
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.185
|
|
|
|
epithelial cell differentiation
|
GO:0030855 |
141 |
0.182
|
|
|
|
peptidyl serine phosphorylation
|
GO:0018105 |
101 |
0.181
|
|
|
|
epithelium development
|
GO:0060429 |
227 |
0.178
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.175
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.162
|
Human |
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.145
|
|
|
|
defense response
|
GO:0006952 |
315 |
0.140
|
|
|
|
immune response
|
GO:0006955 |
307 |
0.137
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.135
|
|
|
|
proteasomal protein catabolic process
|
GO:0010498 |
176 |
0.130
|
Human |
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.129
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.128
|
|
|
|
regulation of protein modification by small protein conjugation or removal
|
GO:1903320 |
107 |
0.128
|
Human |
|
|
regulation of peptidase activity
|
GO:0052547 |
180 |
0.126
|
|
|
|
protein k48 linked ubiquitination
|
GO:0070936 |
38 |
0.123
|
|
|
|
cell activation
|
GO:0001775 |
213 |
0.122
|
|
|
|
regulation of ion transmembrane transport
|
GO:0034765 |
132 |
0.118
|
|
|
|
bmp signaling pathway
|
GO:0030509 |
49 |
0.113
|
|
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.112
|
|
|
|
response to uv
|
GO:0009411 |
73 |
0.109
|
|
|
|
protein autophosphorylation
|
GO:0046777 |
123 |
0.103
|
|
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.102
|
|
|
|
response to growth factor
|
GO:0070848 |
205 |
0.100
|
|
|
|
positive regulation of osteoblast differentiation
|
GO:0045669 |
23 |
0.099
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.098
|
|
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.098
|
|
|
|
regulation of protein ubiquitination
|
GO:0031396 |
95 |
0.098
|
Human |
|
|
establishment of protein localization to organelle
|
GO:0072594 |
172 |
0.097
|
|
|
|
regulation of immune response
|
GO:0050776 |
201 |
0.097
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.097
|
Human |
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
70 |
0.096
|
|
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.096
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.095
|
|
|
|
endosomal transport
|
GO:0016197 |
129 |
0.094
|
|
|
|
canonical wnt signaling pathway
|
GO:0060070 |
116 |
0.093
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.092
|
|
|
|
response to transforming growth factor beta
|
GO:0071559 |
94 |
0.092
|
|
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.092
|
|
|
|
regulation of defense response
|
GO:0031347 |
154 |
0.090
|
|
|
|
positive regulation of defense response
|
GO:0031349 |
87 |
0.089
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.089
|
|
|
|
defense response to other organism
|
GO:0098542 |
129 |
0.088
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.085
|
|
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.085
|
|
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
41 |
0.084
|
|
|
|
mitotic cell cycle phase transition
|
GO:0044772 |
162 |
0.083
|
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.082
|
|
|
|
protein targeting
|
GO:0006605 |
187 |
0.081
|
|
|
|
ion transmembrane transport
|
GO:0034220 |
338 |
0.081
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.080
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.078
|
|
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.078
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.077
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.077
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
149 |
0.076
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
136 |
0.076
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.076
|
|
|
|
toll like receptor 2 signaling pathway
|
GO:0034134 |
4 |
0.076
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.075
|
|
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
127 |
0.074
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
125 |
0.074
|
|
|
|
regulation of protein localization to nucleus
|
GO:1900180 |
85 |
0.074
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.074
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.073
|
Human |
|
|
wnt signaling pathway
|
GO:0016055 |
156 |
0.072
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.071
|
|
|
|
neural crest cell development
|
GO:0014032 |
3 |
0.070
|
|
|
|
wound healing
|
GO:0042060 |
115 |
0.070
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.069
|
|
|
|
cell projection organization
|
GO:0030030 |
252 |
0.069
|
|
|
|
positive regulation of intracellular protein transport
|
GO:0090316 |
76 |
0.069
|
|
|
|
histone modification
|
GO:0016570 |
251 |
0.069
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
195 |
0.068
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.068
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.067
|
|
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.067
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.067
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.065
|
|
|
|
regulation of dna metabolic process
|
GO:0051052 |
153 |
0.064
|
|
|
|
transforming growth factor beta receptor signaling pathway
|
GO:0007179 |
76 |
0.064
|
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.064
|
|
|
|
cellular response to abiotic stimulus
|
GO:0071214 |
117 |
0.063
|
|
|
|
response to nitrogen compound
|
GO:1901698 |
184 |
0.063
|
|
|
|
cellular response to transforming growth factor beta stimulus
|
GO:0071560 |
94 |
0.063
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.063
|
|
|
|
mononuclear cell proliferation
|
GO:0032943 |
71 |
0.062
|
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
130 |
0.062
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
213 |
0.062
|
Human |
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.061
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.060
|
|
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.060
|
|
|
|
peptidyl threonine phosphorylation
|
GO:0018107 |
41 |
0.060
|
|
|
|
cellular response to light stimulus
|
GO:0071482 |
34 |
0.060
|
|
|
|
cytokine production
|
GO:0001816 |
247 |
0.060
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.059
|
|
|
|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
156 |
0.059
|
Human |
|
|
response to light stimulus
|
GO:0009416 |
87 |
0.058
|
|
|
|
response to other organism
|
GO:0051707 |
261 |
0.057
|
|
|
|
regulation of innate immune response
|
GO:0045088 |
97 |
0.057
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.057
|
|
|
|
regulation of nucleocytoplasmic transport
|
GO:0046822 |
98 |
0.057
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
125 |
0.056
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
0.056
|
|
|
|
hemopoiesis
|
GO:0030097 |
180 |
0.056
|
|
|
|
positive regulation of intracellular transport
|
GO:0032388 |
104 |
0.056
|
|
|
|
chromatin modification
|
GO:0016568 |
298 |
0.055
|
|
|
|
lysosomal transport
|
GO:0007041 |
33 |
0.055
|
|
|
|
regulation of multi organism process
|
GO:0043900 |
157 |
0.055
|
|
|
|
divalent metal ion transport
|
GO:0070838 |
152 |
0.055
|
|
|
|
negative regulation of multi organism process
|
GO:0043901 |
92 |
0.054
|
|
|
|
transmembrane transport
|
GO:0055085 |
399 |
0.054
|
|
|
|
regulation of cell cycle phase transition
|
GO:1901987 |
126 |
0.053
|
|
|
|
positive regulation of protein catabolic process
|
GO:0045732 |
75 |
0.053
|
|
|
|
regulation of canonical wnt signaling pathway
|
GO:0060828 |
88 |
0.053
|
|
|
|
negative regulation of cell cycle process
|
GO:0010948 |
121 |
0.053
|
|
|
|
regulation of protein stability
|
GO:0031647 |
87 |
0.053
|
Human |
|
|
nucleocytoplasmic transport
|
GO:0006913 |
176 |
0.053
|
|
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.052
|
|
|
|
positive regulation of cytoplasmic transport
|
GO:1903651 |
82 |
0.052
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
75 |
0.052
|
|
|
|
regulation of homeostatic process
|
GO:0032844 |
121 |
0.051
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.051
|
|
|
|
regulation of t cell proliferation
|
GO:0042129 |
42 |
0.051
|
|
|
|
covalent chromatin modification
|
GO:0016569 |
254 |
0.051
|
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.051
|
|
|
|
somitogenesis
|
GO:0001756 |
2 |
0.051
|
|
|
|
regulation of endopeptidase activity
|
GO:0052548 |
170 |
0.051
|
|
|
|
negative regulation of organelle organization
|
GO:0010639 |
126 |
0.050
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.049
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
193 |
0.049
|
|
|
|
single organism nuclear import
|
GO:1902593 |
104 |
0.049
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.049
|
|
|
|
regulation of meiotic cell cycle
|
GO:0051445 |
4 |
0.048
|
|
|
|
immune effector process
|
GO:0002252 |
159 |
0.048
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.048
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
124 |
0.048
|
|
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.047
|
|
|
|
protein processing
|
GO:0016485 |
226 |
0.047
|
|
|
|
regulation of transmembrane transport
|
GO:0034762 |
139 |
0.047
|
|
|
|
cellular response to nitrogen compound
|
GO:1901699 |
144 |
0.045
|
|
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043281 |
116 |
0.045
|
|
|
|
aging
|
GO:0007568 |
66 |
0.045
|
|
|
|
protein monoubiquitination
|
GO:0006513 |
39 |
0.045
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.045
|
Human |
|
|
regulation of immune effector process
|
GO:0002697 |
91 |
0.045
|
|
|
|
regulation of protein maturation
|
GO:1903317 |
150 |
0.044
|
|
|
|
actin filament based process
|
GO:0030029 |
224 |
0.044
|
|
|
|
histone ubiquitination
|
GO:0016574 |
31 |
0.043
|
|
|
|
negative regulation of blood pressure
|
GO:0045776 |
3 |
0.043
|
|
|
|
cellular response to radiation
|
GO:0071478 |
65 |
0.043
|
|
|
|
positive regulation of protein transport
|
GO:0051222 |
135 |
0.043
|
|
|
|
protein k63 linked ubiquitination
|
GO:0070534 |
31 |
0.043
|
|
|
|
regulation of protein targeting
|
GO:1903533 |
91 |
0.043
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.043
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.042
|
|
|
|
stem cell division
|
GO:0017145 |
2 |
0.042
|
|
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.042
|
|
|
|
regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090092 |
90 |
0.042
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
261 |
0.042
|
Human |
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.041
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.041
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.041
|
|
|
|
segmentation
|
GO:0035282 |
4 |
0.041
|
|
|
|
blood circulation
|
GO:0008015 |
113 |
0.041
|
|
|
|
regulation of response to external stimulus
|
GO:0032101 |
222 |
0.041
|
|
|
|
oogenesis
|
GO:0048477 |
2 |
0.040
|
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
94 |
0.040
|
|
|
|
regulation of lymphocyte proliferation
|
GO:0050670 |
64 |
0.040
|
|
|
|
response to radiation
|
GO:0009314 |
151 |
0.040
|
|
|
|
positive regulation of innate immune response
|
GO:0045089 |
79 |
0.040
|
|
|
|
regulation of cysteine type endopeptidase activity
|
GO:2000116 |
127 |
0.040
|
|
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
207 |
0.040
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.040
|
|
|
|
g1 s transition of mitotic cell cycle
|
GO:0000082 |
78 |
0.039
|
|
|
|
response to external biotic stimulus
|
GO:0043207 |
261 |
0.039
|
|
|
|
positive regulation of wnt signaling pathway
|
GO:0030177 |
54 |
0.039
|
|
|
|
nuclear transport
|
GO:0051169 |
179 |
0.039
|
|
|
|
cell cycle checkpoint
|
GO:0000075 |
117 |
0.039
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.039
|
|
|
|
metal ion transport
|
GO:0030001 |
272 |
0.039
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.038
|
|
|
|
positive regulation of immune response
|
GO:0050778 |
159 |
0.038
|
|
|
|
regulation of leukocyte activation
|
GO:0002694 |
115 |
0.038
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.037
|
|
|
|
response to wounding
|
GO:0009611 |
168 |
0.037
|
|
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
144 |
0.037
|
|
|
|
cell cycle g1 s phase transition
|
GO:0044843 |
80 |
0.037
|
|
|
|
negative regulation of dna metabolic process
|
GO:0051053 |
57 |
0.037
|
|
|
|
positive regulation of cellular component movement
|
GO:0051272 |
181 |
0.037
|
|
|
|
protein oligomerization
|
GO:0051259 |
173 |
0.036
|
|
|
|
single organismal cell cell adhesion
|
GO:0016337 |
148 |
0.036
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
103 |
0.036
|
|
|
|
regulation of transmembrane transporter activity
|
GO:0022898 |
74 |
0.036
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.036
|
|
|
|
stress activated mapk cascade
|
GO:0051403 |
93 |
0.036
|
|
|
|
regulation of leukocyte proliferation
|
GO:0070663 |
67 |
0.036
|
|
|
|
t cell activation
|
GO:0042110 |
99 |
0.036
|
|
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
324 |
0.036
|
Human |
|
|
protein autoubiquitination
|
GO:0051865 |
37 |
0.036
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.035
|
|
|
|
regulation of interleukin 8 production
|
GO:0032677 |
49 |
0.035
|
|
|
|
peptidyl serine modification
|
GO:0018209 |
106 |
0.035
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.035
|
|
|
|
lymphocyte proliferation
|
GO:0046651 |
70 |
0.035
|
|
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.035
|
|
|
|
lymphocyte apoptotic process
|
GO:0070227 |
20 |
0.034
|
|
|
|
leukocyte proliferation
|
GO:0070661 |
74 |
0.034
|
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
127 |
0.034
|
|
|
|
cell cycle phase transition
|
GO:0044770 |
173 |
0.034
|
|
|
|
cell adhesion
|
GO:0007155 |
325 |
0.034
|
|
|
|
lymphocyte activation
|
GO:0046649 |
133 |
0.034
|
|
|
|
ncrna metabolic process
|
GO:0034660 |
108 |
0.034
|
|
|
|
response to decreased oxygen levels
|
GO:0036293 |
96 |
0.034
|
Human |
|
|
regulation of leukocyte apoptotic process
|
GO:2000106 |
25 |
0.034
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.033
|
|
|
|
protein import
|
GO:0017038 |
130 |
0.033
|
|
|
|
regulation of cell activation
|
GO:0050865 |
125 |
0.033
|
|
|
|
chemical homeostasis
|
GO:0048878 |
306 |
0.033
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
191 |
0.033
|
|
|
|
protein maturation
|
GO:0051604 |
233 |
0.032
|
|
|
|
regulation of mononuclear cell proliferation
|
GO:0032944 |
65 |
0.032
|
|
|
|
taxis
|
GO:0042330 |
157 |
0.032
|
|
|
|
negative regulation of cell cycle phase transition
|
GO:1901988 |
89 |
0.032
|
|
|
|
calcium ion transport
|
GO:0006816 |
147 |
0.032
|
|
|
|
peptidyl lysine modification
|
GO:0018205 |
144 |
0.032
|
|
|
|
negative regulation of peptidase activity
|
GO:0010466 |
91 |
0.031
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
136 |
0.031
|
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
155 |
0.031
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
204 |
0.030
|
|
|
|
positive regulation of canonical wnt signaling pathway
|
GO:0090263 |
33 |
0.030
|
|
|
|
regulation of adaptive immune response
|
GO:0002819 |
33 |
0.030
|
|
|
|
regulation of protein processing
|
GO:0070613 |
150 |
0.030
|
|
|
|
cell part morphogenesis
|
GO:0032990 |
137 |
0.030
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.030
|
|
|
|
generation of neurons
|
GO:0048699 |
152 |
0.030
|
|
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
60 |
0.030
|
|
|
|
biological adhesion
|
GO:0022610 |
331 |
0.029
|
|
|
|
positive regulation of protein localization to nucleus
|
GO:1900182 |
48 |
0.029
|
|
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
84 |
0.029
|
|
|
|
cell projection morphogenesis
|
GO:0048858 |
129 |
0.029
|
|
|
|
protein stabilization
|
GO:0050821 |
64 |
0.029
|
|
|
|
cell growth
|
GO:0016049 |
160 |
0.029
|
|
|
|
ion homeostasis
|
GO:0050801 |
230 |
0.029
|
|
|
|
positive regulation of endopeptidase activity
|
GO:0010950 |
84 |
0.029
|
|
|
|
alcohol metabolic process
|
GO:0006066 |
114 |
0.029
|
|
|
|
protein targeting to nucleus
|
GO:0044744 |
104 |
0.028
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.028
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.028
|
|
|
|
cellular response to uv
|
GO:0034644 |
32 |
0.028
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
189 |
0.028
|
|
|
|
leukocyte migration
|
GO:0050900 |
107 |
0.028
|
|
|
|
positive regulation of protein import into nucleus
|
GO:0042307 |
46 |
0.028
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
172 |
0.028
|
|
|
|
secretion
|
GO:0046903 |
254 |
0.027
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.027
|
|
|
|
leukocyte apoptotic process
|
GO:0071887 |
31 |
0.027
|
|
|
|
lipid metabolic process
|
GO:0006629 |
381 |
0.027
|
|
|
|
positive regulation of secretion by cell
|
GO:1903532 |
108 |
0.027
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
209 |
0.027
|
|
|
|
neuromuscular junction development
|
GO:0007528 |
3 |
0.027
|
|
|
|
leukocyte activation
|
GO:0045321 |
164 |
0.027
|
|
|
|
circulatory system process
|
GO:0003013 |
113 |
0.027
|
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
142 |
0.026
|
|
|
|
response to tumor necrosis factor
|
GO:0034612 |
76 |
0.026
|
|
|
|
regulation of stress activated protein kinase signaling cascade
|
GO:0070302 |
85 |
0.026
|
|
|
|
positive regulation of reactive oxygen species metabolic process
|
GO:2000379 |
24 |
0.026
|
|
|
|
extrinsic apoptotic signaling pathway via death domain receptors
|
GO:0008625 |
42 |
0.026
|
|
|
|
t cell proliferation
|
GO:0042098 |
45 |
0.026
|
|
|
|
regulation of meiosis
|
GO:0040020 |
3 |
0.026
|
|
|
|
positive regulation of peptidase activity
|
GO:0010952 |
88 |
0.025
|
|
|
|
cation transport
|
GO:0006812 |
331 |
0.025
|
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
176 |
0.025
|
|
|
|
regulation of growth
|
GO:0040008 |
165 |
0.025
|
|
|
|
neuroblast proliferation
|
GO:0007405 |
4 |
0.025
|
|
|
|
histone h2a ubiquitination
|
GO:0033522 |
17 |
0.024
|
|
|
|
regulation of leukocyte migration
|
GO:0002685 |
63 |
0.024
|
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
123 |
0.024
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.024
|
|
|
|
peptidyl threonine modification
|
GO:0018210 |
45 |
0.024
|
|
|
|
endocardial cushion development
|
GO:0003197 |
3 |
0.024
|
|
|
|
negative regulation of cell differentiation
|
GO:0045596 |
171 |
0.024
|
|
|
|
negative regulation of transport
|
GO:0051051 |
176 |
0.024
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.024
|
|
|
|
negative regulation of cell adhesion
|
GO:0007162 |
64 |
0.024
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.024
|
|
|
|
positive regulation of protein ubiquitination
|
GO:0031398 |
53 |
0.023
|
|
|
|
regulation of cell growth
|
GO:0001558 |
135 |
0.023
|
|
|
|
negative regulation of chromosome organization
|
GO:2001251 |
48 |
0.023
|
|
|
|
activation of protein kinase activity
|
GO:0032147 |
90 |
0.023
|
|
|
|
cell junction assembly
|
GO:0034329 |
67 |
0.023
|
|
|
|
peptidyl serine autophosphorylation
|
GO:0036289 |
2 |
0.023
|
|
|
|
programmed necrotic cell death
|
GO:0097300 |
18 |
0.023
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.023
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.023
|
|
|
|
mitotic cell cycle checkpoint
|
GO:0007093 |
68 |
0.023
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.023
|
|
|
|
osteoblast differentiation
|
GO:0001649 |
92 |
0.022
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
398 |
0.022
|
|
|
|
skin development
|
GO:0043588 |
76 |
0.022
|
|
|
|
cellular homeostasis
|
GO:0019725 |
196 |
0.022
|
|
|
|
negative regulation of proteolysis
|
GO:0045861 |
132 |
0.022
|
|
|
|
regulation of lymphocyte apoptotic process
|
GO:0070228 |
15 |
0.022
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
269 |
0.022
|
|
|
|
regulation of ion transport
|
GO:0043269 |
189 |
0.022
|
|
|
|
response to lipid
|
GO:0033993 |
206 |
0.022
|
|
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
136 |
0.022
|
|
|
|
dna replication
|
GO:0006260 |
116 |
0.022
|
|
|
|
inner ear morphogenesis
|
GO:0042472 |
4 |
0.022
|
|
|
|
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090101 |
45 |
0.022
|
|
|
|
ncrna processing
|
GO:0034470 |
83 |
0.022
|
|
|
|
positive regulation of erk1 and erk2 cascade
|
GO:0070374 |
75 |
0.022
|
|
|
|
jnk cascade
|
GO:0007254 |
80 |
0.022
|
|
|
|
regulation of cell morphogenesis
|
GO:0022604 |
153 |
0.022
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
117 |
0.022
|
|
|
|
negative regulation of locomotion
|
GO:0040013 |
118 |
0.022
|
|
|
|
regulation of neurotransmitter secretion
|
GO:0046928 |
3 |
0.022
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.022
|
|
|
|
regulation of chorionic trophoblast cell proliferation
|
GO:1901382 |
2 |
0.022
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
177 |
0.022
|
|
|
|
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002460 |
40 |
0.022
|
|
|
|
mrna metabolic process
|
GO:0016071 |
175 |
0.022
|
Human |
|
|
spermatid development
|
GO:0007286 |
4 |
0.021
|
|
|
|
macromolecular complex disassembly
|
GO:0032984 |
60 |
0.021
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.021
|
|
|
|
neuron development
|
GO:0048666 |
113 |
0.021
|
|
|
|
positive regulation of secretion
|
GO:0051047 |
116 |
0.021
|
|
|
|
negative regulation of transforming growth factor beta receptor signaling pathway
|
GO:0030512 |
28 |
0.021
|
|
|
|
positive regulation of locomotion
|
GO:0040017 |
186 |
0.021
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.021
|
|
|
|
negative regulation of defense response
|
GO:0031348 |
47 |
0.021
|
|
|
|
negative regulation of protein maturation
|
GO:1903318 |
142 |
0.021
|
|
|
|
dna repair
|
GO:0006281 |
198 |
0.021
|
|
|
|
defense response to virus
|
GO:0051607 |
71 |
0.021
|
|
|
|
growth
|
GO:0040007 |
202 |
0.021
|
|
|
|
negative regulation of endopeptidase activity
|
GO:0010951 |
84 |
0.021
|
|
|
|
negative regulation of chorionic trophoblast cell proliferation
|
GO:1901383 |
2 |
0.021
|
|
|
|
regulation of phosphatase activity
|
GO:0010921 |
81 |
0.020
|
|
|
|
immune response activating signal transduction
|
GO:0002757 |
90 |
0.020
|
|
|
|
maintenance of location
|
GO:0051235 |
112 |
0.020
|
|
|
|
gland development
|
GO:0048732 |
48 |
0.020
|
|
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.020
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
180 |
0.020
|
|
|
|
protein import into nucleus
|
GO:0006606 |
104 |
0.020
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
303 |
0.020
|
|
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
61 |
0.020
|
|
|
|
response to cytokine
|
GO:0034097 |
232 |
0.020
|
|
|
|
rna interference
|
GO:0016246 |
4 |
0.020
|
|
|
|
regulation of myeloid cell differentiation
|
GO:0045637 |
81 |
0.020
|
|
|
|
hindbrain development
|
GO:0030902 |
3 |
0.020
|
|
|
|
positive regulation of protein modification by small protein conjugation or removal
|
GO:1903322 |
61 |
0.020
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
227 |
0.020
|
|
|
|
activation of innate immune response
|
GO:0002218 |
55 |
0.020
|
|
|
|
er associated ubiquitin dependent protein catabolic process
|
GO:0030433 |
31 |
0.020
|
Human |
|
|
sequestering of metal ion
|
GO:0051238 |
24 |
0.020
|
|
|
|
defense response to bacterium
|
GO:0042742 |
63 |
0.020
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
391 |
0.020
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
155 |
0.020
|
|
|
|
anterior posterior axis specification
|
GO:0009948 |
2 |
0.020
|
|
|
|
adaptive immune response
|
GO:0002250 |
49 |
0.019
|
|
|
|
system process
|
GO:0003008 |
349 |
0.019
|
|
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
182 |
0.019
|
|
|
|
protein complex disassembly
|
GO:0043241 |
52 |
0.019
|
|
|
|
head development
|
GO:0060322 |
108 |
0.019
|
|
|
|
response to virus
|
GO:0009615 |
126 |
0.019
|
|
|
|
chromatin assembly or disassembly
|
GO:0006333 |
78 |
0.019
|
|
|
|
positive regulation of myeloid cell differentiation
|
GO:0045639 |
39 |
0.019
|
|
|
|
rna processing
|
GO:0006396 |
255 |
0.019
|
Human |
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
119 |
0.019
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
211 |
0.019
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.019
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
63 |
0.019
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
412 |
0.019
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
104 |
0.019
|
|
|
|
regulation of cell junction assembly
|
GO:1901888 |
29 |
0.019
|
|
|
|
cardiovascular system development
|
GO:0072358 |
262 |
0.019
|
|
|
|
nuclear import
|
GO:0051170 |
106 |
0.019
|
|
|
|
positive regulation of cell cycle
|
GO:0045787 |
140 |
0.018
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
405 |
0.018
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
404 |
0.018
|
|
|
|
activation of immune response
|
GO:0002253 |
114 |
0.018
|
|
|
|
granulocyte chemotaxis
|
GO:0071621 |
37 |
0.018
|
|
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
99 |
0.018
|
|
|
|
protein homooligomerization
|
GO:0051260 |
100 |
0.018
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.018
|
Human |
|
|
positive regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043280 |
69 |
0.018
|
|
|
|
ossification
|
GO:0001503 |
121 |
0.018
|
|
|
|
cell projection assembly
|
GO:0030031 |
126 |
0.018
|
|
|
|
dephosphorylation
|
GO:0016311 |
209 |
0.018
|
|
|
|
neuron projection development
|
GO:0031175 |
106 |
0.018
|
|
|
|
chemotaxis
|
GO:0006935 |
157 |
0.018
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.018
|
|
|
|
central nervous system development
|
GO:0007417 |
123 |
0.018
|
|
|
|
negative regulation of protein processing
|
GO:0010955 |
142 |
0.018
|
|
|
|
leukocyte chemotaxis
|
GO:0030595 |
76 |
0.018
|
|
|
|
protein ubiquitination involved in ubiquitin dependent protein catabolic process
|
GO:0042787 |
37 |
0.018
|
|
|
|
mitral valve development
|
GO:0003174 |
3 |
0.018
|
|
|
|
regulation of extrinsic apoptotic signaling pathway via death domain receptors
|
GO:1902041 |
24 |
0.018
|
|
|
|
regulation of mitotic cell cycle phase transition
|
GO:1901990 |
118 |
0.018
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
166 |
0.018
|
|
|
|
positive regulation of cell cycle process
|
GO:0090068 |
106 |
0.018
|
|
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
166 |
0.018
|
|
|
|
reactive nitrogen species metabolic process
|
GO:2001057 |
3 |
0.018
|
|
|
|
regulation of ossification
|
GO:0030278 |
58 |
0.018
|
|
|
|
receptor metabolic process
|
GO:0043112 |
81 |
0.018
|
|
|
|
activation of mapkk activity
|
GO:0000186 |
18 |
0.017
|
|
|
|
carboxylic acid biosynthetic process
|
GO:0046394 |
97 |
0.017
|
|
|
|
regulation of reactive oxygen species biosynthetic process
|
GO:1903426 |
3 |
0.017
|
|
|
|
response to alcohol
|
GO:0097305 |
64 |
0.017
|
|
|
|
organic acid biosynthetic process
|
GO:0016053 |
97 |
0.017
|
|
|
|
negative regulation of mitotic cell cycle
|
GO:0045930 |
102 |
0.017
|
|
|
|
positive regulation of gtpase activity
|
GO:0043547 |
166 |
0.017
|
|
|
|
circulatory system development
|
GO:0072359 |
262 |
0.017
|
|
|
|
endocytosis
|
GO:0006897 |
159 |
0.017
|
|
|
|
regulation of t cell tolerance induction
|
GO:0002664 |
4 |
0.017
|
|
|
|
regulation of pathway restricted smad protein phosphorylation
|
GO:0060393 |
34 |
0.017
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
169 |
0.017
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
207 |
0.017
|
|
|
|
embryo development
|
GO:0009790 |
123 |
0.017
|
|
|
|
epithelial cell development
|
GO:0002064 |
34 |
0.017
|
|
|
|
regulation of activin receptor signaling pathway
|
GO:0032925 |
14 |
0.017
|
|
|
|
syncytium formation by plasma membrane fusion
|
GO:0000768 |
2 |
0.016
|
|
|
|
defense response to fungus
|
GO:0050832 |
4 |
0.016
|
|
|
|
regulation of biomineral tissue development
|
GO:0070167 |
31 |
0.016
|
|
|
|
regulation of cell cell adhesion
|
GO:0022407 |
57 |
0.016
|
|
|
|
positive regulation of stress activated mapk cascade
|
GO:0032874 |
60 |
0.016
|
|
|
|
negative regulation of mitotic cell cycle phase transition
|
GO:1901991 |
85 |
0.016
|
|
|
|
regulation of chromosome organization
|
GO:0033044 |
103 |
0.016
|
|
|
|
dorsal ventral pattern formation
|
GO:0009953 |
15 |
0.016
|
|
|
|
microtubule organizing center organization
|
GO:0031023 |
62 |
0.016
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.016
|
|
|
|
regulation of intrinsic apoptotic signaling pathway
|
GO:2001242 |
72 |
0.016
|
|
|
|
blastoderm segmentation
|
GO:0007350 |
2 |
0.016
|
|
|
|
negative regulation of systemic arterial blood pressure
|
GO:0003085 |
1 |
0.016
|
|
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
147 |
0.016
|
|
|
|
calcium ion homeostasis
|
GO:0055074 |
122 |
0.016
|
|
|
|
negative regulation of endothelial cell migration
|
GO:0010596 |
29 |
0.016
|
|
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.016
|
|
|
|
response to fungus
|
GO:0009620 |
4 |
0.016
|
|
|
|
negative regulation of cell growth
|
GO:0030308 |
83 |
0.016
|
|
|
|
ribonucleoprotein complex biogenesis
|
GO:0022613 |
116 |
0.016
|
Human |
|
|
ribonucleoside monophosphate metabolic process
|
GO:0009161 |
187 |
0.016
|
|
|
|
positive regulation of exosomal secretion
|
GO:1903543 |
12 |
0.016
|
|
|
|
negative regulation of i kappab kinase nf kappab signaling
|
GO:0043124 |
32 |
0.016
|
|
|
|
cellular response to nutrient levels
|
GO:0031669 |
69 |
0.016
|
|
|
|
negative regulation of epithelial cell migration
|
GO:0010633 |
38 |
0.015
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
264 |
0.015
|
|
|
|
regulation of cellular protein catabolic process
|
GO:1903362 |
96 |
0.015
|
|
|
|
neurotransmitter secretion
|
GO:0007269 |
4 |
0.015
|
|
