Homo sapiens

18 known processes

DEFA4

defensin, alpha 4, corticostatin

(Aliases: HNP-4,MGC120099,DEF4,HP-4,MGC138296,HP4)

DEFA4 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
response to other organism GO:0051707 261 0.245
response to biotic stimulus GO:0009607 276 0.241
defense response to other organism GO:0098542 129 0.212
cytokine production GO:0001816 247 0.210
defense response GO:0006952 315 0.208
defense response to bacterium GO:0042742 63 0.166
response to bacterium GO:0009617 144 0.154
immune response GO:0006955 307 0.142
biological adhesion GO:0022610 331 0.140
regulation of cytokine production GO:0001817 232 0.138
positive regulation of transport GO:0051050 336 0.130
response to external biotic stimulus GO:0043207 261 0.129
cation transport GO:0006812 331 0.123
glial cell migration GO:0008347 4 0.115
positive regulation of immune system process GO:0002684 283 0.113
regulation of cellular component movement GO:0051270 334 0.100
regulation of locomotion GO:0040012 329 0.095
response to lipopolysaccharide GO:0032496 70 0.084
Mouse
response to oxygen containing compound GO:1901700 369 0.076
Mouse
response to molecule of bacterial origin GO:0002237 82 0.074
Mouse
immune system development GO:0002520 195 0.071
hemopoiesis GO:0030097 180 0.070
cell adhesion GO:0007155 325 0.070
regulation of ion transport GO:0043269 189 0.068
mature dendritic cell differentiation GO:0097029 2 0.067
negative regulation of protein metabolic process GO:0051248 391 0.065
chemical homeostasis GO:0048878 306 0.062
positive regulation of immune response GO:0050778 159 0.062
positive regulation of cytokine production GO:0001819 167 0.061
hematopoietic or lymphoid organ development GO:0048534 186 0.060
response to abiotic stimulus GO:0009628 336 0.056
cation homeostasis GO:0055080 189 0.056
innate immune response GO:0045087 178 0.055
ion transmembrane transport GO:0034220 338 0.052
regulation of tumor necrosis factor superfamily cytokine production GO:1903555 44 0.052
negative regulation of transport GO:0051051 176 0.051
response to lipid GO:0033993 206 0.051
Mouse
ion homeostasis GO:0050801 230 0.050
transmembrane transport GO:0055085 399 0.050
cell activation GO:0001775 213 0.049
myeloid cell differentiation GO:0030099 117 0.048
post embryonic development GO:0009791 2 0.048
vesicle mediated transport GO:0016192 371 0.047
regulation of cell motility GO:2000145 299 0.047
lipid metabolic process GO:0006629 381 0.047
metal ion transport GO:0030001 272 0.045
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.045
cellular amino acid metabolic process GO:0006520 116 0.045
cellular response to oxygen containing compound GO:1901701 276 0.044
Mouse
secretion GO:0046903 254 0.044
cellular ion homeostasis GO:0006873 168 0.044
inorganic cation transmembrane transport GO:0098662 194 0.044
regulation of immune response GO:0050776 201 0.044
system process GO:0003008 349 0.044
single organism cell adhesion GO:0098602 179 0.043
monocarboxylic acid metabolic process GO:0032787 185 0.041
inorganic ion transmembrane transport GO:0098660 231 0.041
negative regulation of cytokine production GO:0001818 82 0.041
regulation of cellular amino acid metabolic process GO:0006521 6 0.041
negative regulation of cellular component organization GO:0051129 235 0.041
metal ion homeostasis GO:0055065 169 0.041
anion transport GO:0006820 161 0.040
oxidation reduction process GO:0055114 396 0.040
regulation of tumor necrosis factor production GO:0032680 43 0.039
regulation of cell migration GO:0030334 289 0.039
disruption by host of symbiont cells GO:0051852 2 0.038
positive regulation of cell death GO:0010942 263 0.038
protein oligomerization GO:0051259 173 0.038
regulation of cell adhesion GO:0030155 166 0.038
g protein coupled receptor signaling pathway GO:0007186 207 0.037
negative regulation of cell death GO:0060548 345 0.037
detection of stimulus GO:0051606 85 0.036
nitrogen compound transport GO:0071705 191 0.036
cellular lipid metabolic process GO:0044255 303 0.036
regulation of multi organism process GO:0043900 157 0.036
regulation of defense response GO:0031347 154 0.036
negative regulation of multicellular organismal process GO:0051241 317 0.036
regulation of cellular amine metabolic process GO:0033238 11 0.036
cellular homeostasis GO:0019725 196 0.035
negative regulation of cellular protein metabolic process GO:0032269 353 0.035
negative regulation of catalytic activity GO:0043086 335 0.035
positive regulation of cellular component organization GO:0051130 376 0.035
positive regulation of apoptotic process GO:0043065 246 0.034
regulation of secretion GO:0051046 194 0.033
single organismal cell cell adhesion GO:0016337 148 0.033
regulation of transferase activity GO:0051338 355 0.033
regulation of establishment of protein localization GO:0070201 242 0.032
amine metabolic process GO:0009308 44 0.032
positive regulation of cell proliferation GO:0008284 301 0.032
innate immune response activating signal transduction GO:0002758 48 0.031
regulation of cellular ketone metabolic process GO:0010565 50 0.031
regulation of cell differentiation GO:0045595 393 0.031
positive regulation of cell adhesion GO:0045785 84 0.031
interleukin 1 biosynthetic process GO:0042222 2 0.031
regulation of kinase activity GO:0043549 314 0.031
cellular calcium ion homeostasis GO:0006874 117 0.030
cytoplasmic transport GO:0016482 379 0.030
defense response to fungus GO:0050832 4 0.030
leukocyte migration GO:0050900 107 0.030
positive regulation of programmed cell death GO:0043068 249 0.030
organic anion transport GO:0015711 103 0.030
negative regulation of programmed cell death GO:0043069 321 0.030
regulation of protein transport GO:0051223 213 0.029
locomotory behavior GO:0007626 1 0.029
blood circulation GO:0008015 113 0.029
positive regulation of phosphorylation GO:0042327 394 0.029
regulation of secretion by cell GO:1903530 177 0.029
protein processing GO:0016485 226 0.029
reactive oxygen species metabolic process GO:0072593 75 0.029
regulation of metal ion transport GO:0010959 120 0.029
vasculature development GO:0001944 181 0.028
regulation of protein secretion GO:0050708 86 0.028
immune response activating signal transduction GO:0002757 90 0.028
interspecies interaction between organisms GO:0044419 156 0.028
regulation of protein localization GO:0032880 296 0.028
protein secretion GO:0009306 98 0.027
regulation of response to external stimulus GO:0032101 222 0.027
regulation of nucleotide metabolic process GO:0006140 269 0.027
cellular cation homeostasis GO:0030003 163 0.027
positive regulation of cellular amine metabolic process GO:0033240 7 0.027
cellular metal ion homeostasis GO:0006875 146 0.027
cellular ketone metabolic process GO:0042180 80 0.027
leukocyte differentiation GO:0002521 98 0.027
ras protein signal transduction GO:0007265 73 0.026
regulation of protein kinase activity GO:0045859 289 0.026
modification of morphology or physiology of other organism GO:0035821 43 0.026
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 109 0.026
response to fungus GO:0009620 4 0.026
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.026
negative regulation of hydrolase activity GO:0051346 182 0.026
positive regulation of developmental process GO:0051094 314 0.026
determination of adult lifespan GO:0008340 2 0.026
negative regulation of cell proliferation GO:0008285 228 0.026
organophosphate catabolic process GO:0046434 430 0.026
blood vessel development GO:0001568 172 0.026
inflammatory response GO:0006954 79 0.026
detection of chemical stimulus GO:0009593 55 0.026
regulation of cell cycle GO:0051726 393 0.026
regulation of vesicle mediated transport GO:0060627 130 0.025
multicellular organismal aging GO:0010259 3 0.025
carbohydrate derivative biosynthetic process GO:1901137 207 0.025
monovalent inorganic cation transport GO:0015672 128 0.025
cellular macromolecule catabolic process GO:0044265 380 0.025
nucleoside phosphate catabolic process GO:1901292 412 0.025
mhc class ii biosynthetic process GO:0045342 4 0.025
negative regulation of apoptotic process GO:0043066 316 0.024
cation transmembrane transport GO:0098655 238 0.024
killing by host of symbiont cells GO:0051873 2 0.024
pattern recognition receptor signaling pathway GO:0002221 48 0.024
detection of chemical stimulus involved in sensory perception GO:0050907 33 0.024
cellular divalent inorganic cation homeostasis GO:0072503 128 0.024
purine nucleoside triphosphate metabolic process GO:0009144 412 0.024
cell killing GO:0001906 34 0.024
response to radiation GO:0009314 151 0.024
positive regulation of cell motility GO:2000147 177 0.024
single organism cellular localization GO:1902580 332 0.024
negative regulation of developmental process GO:0051093 247 0.024
activation of innate immune response GO:0002218 55 0.023
apoptotic signaling pathway GO:0097190 268 0.023
regulation of smooth muscle cell proliferation GO:0048660 28 0.023
regulation of endopeptidase activity GO:0052548 170 0.023
chromatin organization GO:0006325 351 0.023
oogenesis GO:0048477 2 0.023
fatty acid metabolic process GO:0006631 115 0.023
organonitrogen compound biosynthetic process GO:1901566 200 0.023
regulation of mapk cascade GO:0043408 262 0.023
activation of immune response GO:0002253 114 0.023
positive regulation of protein transport GO:0051222 135 0.023
protein maturation GO:0051604 233 0.023
cellular chemical homeostasis GO:0055082 180 0.022
positive regulation of cell migration GO:0030335 172 0.022
glycosyl compound catabolic process GO:1901658 413 0.022
cell chemotaxis GO:0060326 112 0.022
negative regulation of phosphate metabolic process GO:0045936 267 0.022
circulatory system development GO:0072359 262 0.022
nervous system development GO:0007399 293 0.022
nucleoside triphosphate metabolic process GO:0009141 422 0.022
negative regulation of phagocytosis GO:0050765 4 0.022
angiogenesis GO:0001525 147 0.022
negative regulation of multi organism process GO:0043901 92 0.022
female gamete generation GO:0007292 2 0.022
positive regulation of catabolic process GO:0009896 310 0.022
regulation of proteolysis GO:0030162 293 0.021
positive regulation of interleukin 8 production GO:0032757 36 0.021
regulation of anatomical structure morphogenesis GO:0022603 286 0.021
cellular response to cytokine stimulus GO:0071345 181 0.021
response to inorganic substance GO:0010035 127 0.021
nucleoside triphosphate catabolic process GO:0009143 394 0.021
immune effector process GO:0002252 159 0.021
regulation of innate immune response GO:0045088 97 0.021
regulation of cell activation GO:0050865 125 0.021
chromatin modification GO:0016568 298 0.021
regulation of interleukin 8 production GO:0032677 49 0.021
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.021
leukocyte activation GO:0045321 164 0.021
ribonucleoside catabolic process GO:0042454 406 0.021
organophosphate biosynthetic process GO:0090407 163 0.020
actin filament based process GO:0030029 224 0.020
secretion by cell GO:0032940 226 0.020
purine ribonucleoside metabolic process GO:0046128 437 0.020
purine ribonucleotide catabolic process GO:0009154 404 0.020
neuromuscular junction development GO:0007528 3 0.020
positive regulation of tumor necrosis factor superfamily cytokine production GO:1903557 22 0.020
negative regulation of locomotion GO:0040013 118 0.020
regeneration GO:0031099 4 0.020
regulation of cellular response to stress GO:0080135 244 0.020
angiotensin activated signaling pathway GO:0038166 4 0.020
cardiac muscle cell contraction GO:0086003 4 0.020
regulation of homeostatic process GO:0032844 121 0.020
negative regulation of phosphorus metabolic process GO:0010563 267 0.020
positive regulation of transferase activity GO:0051347 227 0.020
negative regulation of protein modification process GO:0031400 200 0.020
protein catabolic process GO:0030163 325 0.019
calcium ion transport GO:0006816 147 0.019
regulation of intracellular transport GO:0032386 195 0.019
positive regulation of hydrolase activity GO:0051345 331 0.019
ribonucleoside triphosphate metabolic process GO:0009199 412 0.019
positive regulation of defense response GO:0031349 87 0.019
small molecule biosynthetic process GO:0044283 157 0.019
regulation of cell cycle process GO:0010564 266 0.019
muscle system process GO:0003012 81 0.019
regulation of apoptotic signaling pathway GO:2001233 175 0.019
signal transduction by phosphorylation GO:0023014 297 0.019
immune response regulating signaling pathway GO:0002764 97 0.019
tumor necrosis factor superfamily cytokine production GO:0071706 45 0.019
positive regulation of secretion by cell GO:1903532 108 0.019
mating GO:0007618 1 0.019
maintenance of location GO:0051235 112 0.018
nucleotide catabolic process GO:0009166 408 0.018
purine nucleoside catabolic process GO:0006152 398 0.018
regulation of growth GO:0040008 165 0.018
ribonucleotide catabolic process GO:0009261 405 0.018
divalent metal ion transport GO:0070838 152 0.018
response to wounding GO:0009611 168 0.018
cellular response to dna damage stimulus GO:0006974 379 0.018
response to hormone GO:0009725 175 0.018
regulation of purine nucleotide metabolic process GO:1900542 264 0.018
covalent chromatin modification GO:0016569 254 0.018
myeloid leukocyte differentiation GO:0002573 60 0.018
cellular protein catabolic process GO:0044257 261 0.018
interleukin 8 production GO:0032637 51 0.018
tumor necrosis factor production GO:0032640 43 0.018
cell development GO:0048468 328 0.018
lipopolysaccharide transport GO:0015920 2 0.018
response to cytokine GO:0034097 232 0.018
membrane organization GO:0061024 292 0.018
positive regulation of organelle organization GO:0010638 195 0.018
negative regulation of immune system process GO:0002683 136 0.018
negative regulation of protein processing GO:0010955 142 0.018
regulation of cellular component biogenesis GO:0044087 281 0.017
ribonucleoside triphosphate catabolic process GO:0009203 391 0.017
cardiovascular system development GO:0072358 262 0.017
rho protein signal transduction GO:0007266 26 0.017
striated muscle contraction GO:0006941 52 0.017
positive regulation of i kappab kinase nf kappab signaling GO:0043123 132 0.017
interleukin 1 beta production GO:0032611 22 0.017
single organism membrane organization GO:0044802 268 0.017
mapk cascade GO:0000165 288 0.017
intracellular protein transport GO:0006886 270 0.017
cytokine biosynthetic process GO:0042089 37 0.017
nucleoside catabolic process GO:0009164 408 0.017
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.017
muscle cell proliferation GO:0033002 35 0.017
sequestering of metal ion GO:0051238 24 0.017
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.017
cytokine secretion GO:0050663 64 0.017
positive regulation of innate immune response GO:0045089 79 0.017
lipid localization GO:0010876 106 0.017
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.017
single organism carbohydrate metabolic process GO:0044723 193 0.017
cellular amine metabolic process GO:0044106 41 0.017
regulation of cytokine biosynthetic process GO:0042035 35 0.017
cell morphogenesis GO:0000902 296 0.017
cellular response to biotic stimulus GO:0071216 71 0.017
Mouse
humoral immune response GO:0006959 49 0.017
positive regulation of protein phosphorylation GO:0001934 313 0.016
purine ribonucleoside catabolic process GO:0046130 398 0.016
negative regulation of phosphorylation GO:0042326 174 0.016
wound healing GO:0042060 115 0.016
positive regulation of ion transport GO:0043270 87 0.016
actin filament based movement GO:0030048 17 0.016
regulation of cytoplasmic transport GO:1903649 149 0.016
purine nucleoside triphosphate catabolic process GO:0009146 392 0.016
nucleoside phosphate biosynthetic process GO:1901293 109 0.016
endocytosis GO:0006897 159 0.016
protein localization to organelle GO:0033365 280 0.016
circulatory system process GO:0003013 113 0.016
antibacterial humoral response GO:0019731 24 0.016
sequestering of calcium ion GO:0051208 17 0.016
purine containing compound catabolic process GO:0072523 411 0.016
i kappab kinase nf kappab signaling GO:0007249 166 0.016
actin mediated cell contraction GO:0070252 12 0.016
regulation of protein processing GO:0070613 150 0.016
sensory perception of taste GO:0050909 36 0.016
reactive nitrogen species metabolic process GO:2001057 3 0.016
cellular response to reactive oxygen species GO:0034614 50 0.016
positive regulation of cellular component movement GO:0051272 181 0.016
positive regulation of intracellular transport GO:0032388 104 0.016
positive regulation of locomotion GO:0040017 186 0.016
anatomical structure formation involved in morphogenesis GO:0048646 284 0.016
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.016
cellular macromolecular complex assembly GO:0034622 324 0.016
divalent inorganic cation transport GO:0072511 158 0.016
reactive oxygen species biosynthetic process GO:1903409 4 0.016
modification dependent protein catabolic process GO:0019941 209 0.016
purine nucleotide catabolic process GO:0006195 405 0.016
positive regulation of cell differentiation GO:0045597 211 0.016
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.016
cellular response to oxidative stress GO:0034599 85 0.016
positive regulation of mapk cascade GO:0043410 190 0.016
intracellular receptor signaling pathway GO:0030522 104 0.016
Human
positive regulation of interleukin 8 biosynthetic process GO:0045416 8 0.016
regulation of calcium ion transport GO:0051924 79 0.015
negative regulation of cell motility GO:2000146 104 0.015
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.015
hemostasis GO:0007599 76 0.015
positive regulation of kinase activity GO:0033674 204 0.015
leukocyte mediated immunity GO:0002443 59 0.015
negative regulation of cell cycle GO:0045786 193 0.015
negative regulation of cellular component movement GO:0051271 106 0.015
positive regulation of nucleotide metabolic process GO:0045981 230 0.015
regulation of ion homeostasis GO:2000021 73 0.015
dephosphorylation GO:0016311 209 0.015
regulation of cell development GO:0060284 161 0.015
growth of symbiont involved in interaction with host GO:0044116 2 0.015
positive regulation of secretion GO:0051047 116 0.015
tissue migration GO:0090130 119 0.015
small gtpase mediated signal transduction GO:0007264 78 0.015
regulation of mhc class ii biosynthetic process GO:0045346 4 0.015
mitotic cell cycle GO:0000278 326 0.015
multi organism cellular process GO:0044764 156 0.015
coagulation GO:0050817 78 0.015
lipid transport GO:0006869 90 0.015
intrinsic apoptotic signaling pathway GO:0097193 127 0.015
regulation of ion transmembrane transport GO:0034765 132 0.015
detection of chemical stimulus involved in sensory perception of smell GO:0050911 2 0.015
regulation of reactive oxygen species biosynthetic process GO:1903426 3 0.015
interleukin 1 beta biosynthetic process GO:0050720 2 0.015
lipid biosynthetic process GO:0008610 177 0.015
negative regulation of intracellular signal transduction GO:1902532 183 0.015
memory GO:0007613 3 0.014
plasma membrane organization GO:0007009 115 0.014
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 43 0.014
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.014
negative regulation of interleukin 8 biosynthetic process GO:0045415 3 0.014
regulation of peptidase activity GO:0052547 180 0.014
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.014
spermatid differentiation GO:0048515 4 0.014
response to decreased oxygen levels GO:0036293 96 0.014
growth GO:0040007 202 0.014
negative regulation of growth GO:0045926 97 0.014
cardiac muscle contraction GO:0060048 34 0.014
positive regulation of protein kinase activity GO:0045860 190 0.014
regulation of feeding behavior GO:0060259 3 0.014
regulation of vasculature development GO:1901342 97 0.014
regulation of system process GO:0044057 101 0.014
histone modification GO:0016570 251 0.014
cytokine metabolic process GO:0042107 38 0.014
negative regulation of cell differentiation GO:0045596 171 0.014
negative regulation of cellular amine metabolic process GO:0033239 3 0.014
actin cytoskeleton organization GO:0030036 207 0.014
endomembrane system organization GO:0010256 196 0.014
carbohydrate metabolic process GO:0005975 207 0.014
mitotic cell cycle process GO:1903047 286 0.014
regulation of response to wounding GO:1903034 101 0.014
regulation of immune effector process GO:0002697 91 0.014
regulation of dna metabolic process GO:0051052 153 0.014
regulation of leukocyte activation GO:0002694 115 0.014
calcium ion homeostasis GO:0055074 122 0.014
regulation of cysteine type endopeptidase activity GO:2000116 127 0.014
positive regulation of cellular catabolic process GO:0031331 284 0.014
response to axon injury GO:0048678 1 0.014
cellular component morphogenesis GO:0032989 314 0.014
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.013
regulation of body fluid levels GO:0050878 99 0.013
regulation of camp metabolic process GO:0030814 52 0.013
muscle contraction GO:0006936 73 0.013
blood coagulation GO:0007596 76 0.013
cellular protein complex assembly GO:0043623 188 0.013
protein ubiquitination GO:0016567 314 0.013
negative regulation of protein maturation GO:1903318 142 0.013
rhythmic behavior GO:0007622 2 0.013
negative regulation of protein phosphorylation GO:0001933 140 0.013
adult locomotory behavior GO:0008344 1 0.013
negative regulation of organelle organization GO:0010639 126 0.013
negative regulation of cell migration GO:0030336 102 0.013
oocyte development GO:0048599 1 0.013
response to tumor necrosis factor GO:0034612 76 0.013
cellular response to endogenous stimulus GO:0071495 336 0.013
regulation of leukocyte migration GO:0002685 63 0.013
growth of symbiont in host GO:0044117 1 0.013
regulation of protein maturation GO:1903317 150 0.013
carboxylic acid transport GO:0046942 63 0.013
positive regulation of leukocyte activation GO:0002696 80 0.013
ribonucleoside monophosphate metabolic process GO:0009161 187 0.013
protein modification by small protein conjugation GO:0032446 342 0.013
response to uv GO:0009411 73 0.013
viral process GO:0016032 146 0.013
protein homooligomerization GO:0051260 100 0.013
amide transport GO:0042886 76 0.013
regulation of reactive oxygen species metabolic process GO:2000377 41 0.013
circadian behavior GO:0048512 2 0.013
cellular response to lipid GO:0071396 127 0.013
Mouse
negative regulation of proteolysis GO:0045861 132 0.013
cell substrate adhesion GO:0031589 132 0.012
regulation of ion transmembrane transporter activity GO:0032412 72 0.012
regulation of protein serine threonine kinase activity GO:0071900 179 0.012
cellular response to nitrogen compound GO:1901699 144 0.012
regulation of cytokine secretion GO:0050707 57 0.012
positive regulation of cell development GO:0010720 92 0.012
epithelial cell migration GO:0010631 119 0.012
regulation of transmembrane transport GO:0034762 139 0.012
negative regulation of hydrogen peroxide metabolic process GO:0010727 3 0.012
positive regulation of cellular component biogenesis GO:0044089 158 0.012
regulation of chromosome organization GO:0033044 103 0.012
response to nitrogen compound GO:1901698 184 0.012
response to organic cyclic compound GO:0014070 204 0.012
chemotaxis GO:0006935 157 0.012
response to extracellular stimulus GO:0009991 85 0.012
purine nucleotide biosynthetic process GO:0006164 84 0.012
ribonucleotide biosynthetic process GO:0009260 81 0.012
atp metabolic process GO:0046034 176 0.012
photoreceptor cell differentiation GO:0046530 2 0.012
positive regulation of nucleoside metabolic process GO:0045979 186 0.012
regulation of chemokine production GO:0032642 31 0.012
positive regulation of keratinocyte migration GO:0051549 4 0.012
establishment of protein localization to organelle GO:0072594 172 0.012
lipid catabolic process GO:0016042 84 0.012
embryonic hemopoiesis GO:0035162 4 0.012
camp biosynthetic process GO:0006171 47 0.012
phospholipid metabolic process GO:0006644 99 0.012
segmentation GO:0035282 4 0.012
second messenger mediated signaling GO:0019932 78 0.012
response to light stimulus GO:0009416 87 0.012
response to nutrient levels GO:0031667 81 0.012
chemokine biosynthetic process GO:0042033 4 0.012
cellular response to hydrogen peroxide GO:0070301 37 0.012
regulation of cell morphogenesis GO:0022604 153 0.012
regulation of binding GO:0051098 111 0.012
positive regulation of tumor necrosis factor production GO:0032760 21 0.012
oocyte differentiation GO:0009994 2 0.012
spermatid development GO:0007286 4 0.012
cellular potassium ion transport GO:0071804 60 0.012
ubiquitin dependent protein catabolic process GO:0006511 206 0.012
protein targeting GO:0006605 187 0.012
erk1 and erk2 cascade GO:0070371 104 0.012
modification dependent macromolecule catabolic process GO:0043632 212 0.012
leukocyte chemotaxis GO:0030595 76 0.012
purine ribonucleotide biosynthetic process GO:0009152 79 0.012
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.012
purine containing compound biosynthetic process GO:0072522 88 0.012
protein localization to membrane GO:0072657 160 0.012
organic acid biosynthetic process GO:0016053 97 0.012
cell division GO:0051301 168 0.011
organelle assembly GO:0070925 176 0.011
sulfur compound metabolic process GO:0006790 101 0.011
nucleotide biosynthetic process GO:0009165 109 0.011
regulation of extrinsic apoptotic signaling pathway GO:2001236 85 0.011
carboxylic acid biosynthetic process GO:0046394 97 0.011
response to oxygen levels GO:0070482 100 0.011
response to virus GO:0009615 126 0.011
negative regulation of transferase activity GO:0051348 124 0.011
viral life cycle GO:0019058 132 0.011
organic acid transport GO:0015849 65 0.011
associative learning GO:0008306 1 0.011
cyclic nucleotide metabolic process GO:0009187 82 0.011
regulation of protein catabolic process GO:0042176 155 0.011
myeloid leukocyte activation GO:0002274 34 0.011
regulation of angiogenesis GO:0045765 92 0.011
posttranscriptional regulation of gene expression GO:0010608 213 0.011
behavioral response to ethanol GO:0048149 2 0.011
nucleoside monophosphate metabolic process GO:0009123 191 0.011
positive regulation of cytokine biosynthetic process GO:0042108 25 0.011
rna processing GO:0006396 255 0.011

DEFA4 disease predictions

Disease DO term ID Size Probability Func Analog Org
immune system disease DOID:2914 155 0.152
hematopoietic system disease DOID:74 100 0.050
disease of metabolism DOID:0014667 295 0.034
inherited metabolic disorder DOID:655 242 0.034
sensory system disease DOID:0050155 203 0.026
nervous system disease DOID:863 431 0.026
musculoskeletal system disease DOID:17 223 0.023
eye and adnexa disease DOID:1492 150 0.020
eye disease DOID:5614 149 0.020
disease of mental health DOID:150 70 0.020
central nervous system disease DOID:331 186 0.019
neurodegenerative disease DOID:1289 102 0.019
retinal disease DOID:5679 118 0.017
night blindness DOID:8499 10 0.017
disease of cellular proliferation DOID:14566 174 0.015
anemia DOID:2355 55 0.014
cancer DOID:162 167 0.013
organ system cancer DOID:0050686 164 0.013
connective tissue disease DOID:65 109 0.012
muscular disease DOID:0080000 114 0.012
muscle tissue disease DOID:66 113 0.012