IMP

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Homo sapiens

10 genes annotated in human

night blindness

DOID:8499

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "night blindness"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "night blindness" (in gray)

Name	Description	Probability	Func Analog Organism
RHO	rhodopsin	0.982
PDE6G	phosphodiesterase 6G, cGMP-specific, rod, gamma	0.533
FCN2	ficolin (collagen/fibrinogen domain containing lectin) 2 (hucolin)	0.514
ARR3	arrestin 3, retinal (X-arrestin)	0.488	Human
KCNJ5	potassium inwardly-rectifying channel, subfamily J, member 5	0.318
SAG	S-antigen; retina and pineal gland (arrestin)	0.289
AQP6	aquaporin 6, kidney specific	0.264
GJD2	gap junction protein, delta 2, 36kDa	0.206
CRYBA4	crystallin, beta A4	0.184
ADRA1D	adrenergic, alpha-1D-, receptor	0.182
SLC6A2	solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2	0.156
RCVRN	recoverin	0.154
CRYBB1	crystallin, beta B1	0.145
KCNA1	potassium voltage-gated channel, shaker-related subfamily, member 1 (episodic ataxia with myokymia)	0.141
KRT9	keratin 9	0.130
CRYBB3	crystallin, beta B3	0.118
RBP3	retinol binding protein 3, interstitial	0.098
NR5A1	nuclear receptor subfamily 5, group A, member 1	0.097
CRHR2	corticotropin releasing hormone receptor 2	0.096
PRLH	prolactin releasing hormone	0.093
NPY2R	neuropeptide Y receptor Y2	0.093
SSTR5	somatostatin receptor 5	0.082
GAD2	glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)	0.082
CACNA1F	calcium channel, voltage-dependent, L type, alpha 1F subunit	0.076
MADCAM1	mucosal vascular addressin cell adhesion molecule 1	0.070
FOXN1	forkhead box N1	0.068
FSCN2	fascin homolog 2, actin-bundling protein, retinal (Strongylocentrotus purpuratus)	0.065
GRK1	G protein-coupled receptor kinase 1	0.064
PSG2	pregnancy specific beta-1-glycoprotein 2	0.059
GPR3	G protein-coupled receptor 3	0.059
FGF4	fibroblast growth factor 4	0.058
NKX6-3	NK6 homeobox 3	0.057
PCBP3	poly(rC) binding protein 3	0.056
SLC1A7	solute carrier family 1 (glutamate transporter), member 7	0.054
RXFP3	relaxin/insulin-like family peptide receptor 3	0.052
GNAT1	guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1	0.051
CRYAA	crystallin, alpha A	0.051
GPR6	G protein-coupled receptor 6	0.050
GH2	growth hormone 2	0.049
CTRC	chymotrypsin C (caldecrin)	0.049
TBX10	T-box 10	0.048
CEACAM3	carcinoembryonic antigen-related cell adhesion molecule 3	0.047
NCR2	natural cytotoxicity triggering receptor 2	0.046
RTBDN	retbindin	0.046
MAPK15	mitogen-activated protein kinase 15	0.044
ZIC4	Zic family member 4	0.042
ENPP7	ectonucleotide pyrophosphatase/phosphodiesterase 7	0.041
NTN3	netrin 3	0.040
GGTLC2	gamma-glutamyltransferase light chain 2	0.039
LRTM1	leucine-rich repeats and transmembrane domains 1	0.039
PAGE1	P antigen family, member 1 (prostate associated)	0.039
IL9R	interleukin 9 receptor	0.038
HNF1A	HNF1 homeobox A	0.036
SLC22A12	solute carrier family 22 (organic anion/urate transporter), member 12	0.036
ZAN	zonadhesin	0.035
OR3A3	olfactory receptor, family 3, subfamily A, member 3	0.035
CARD14	caspase recruitment domain family, member 14	0.035
TEX13B	testis expressed 13B	0.035
CABP4	calcium binding protein 4	0.034
ACRV1	acrosomal vesicle protein 1	0.034
ADARB2	adenosine deaminase, RNA-specific, B2	0.034
GUCA1B	guanylate cyclase activator 1B (retina)	0.033
CYP1A2	cytochrome P450, family 1, subfamily A, polypeptide 2	0.033
EMX1	empty spiracles homeobox 1	0.033
OTOF	otoferlin	0.033
ROM1	retinal outer segment membrane protein 1	0.033
EFNA2	ephrin-A2	0.032
SLC14A2	solute carrier family 14 (urea transporter), member 2	0.032
OPRL1	opiate receptor-like 1	0.031
AVPR2	arginine vasopressin receptor 2	0.031
RS1	retinoschisin 1	0.030
CTAG2	cancer/testis antigen 2	0.030
FCER2	Fc fragment of IgE, low affinity II, receptor for (CD23)	0.029
GJC2	gap junction protein, gamma 2, 47kDa	0.029
SLC6A18	solute carrier family 6, member 18	0.029
LRIT1	leucine-rich repeat, immunoglobulin-like and transmembrane domains 1	0.029
MSI1	musashi homolog 1 (Drosophila)	0.029
ELSPBP1	epididymal sperm binding protein 1	0.028
SOX3	SRY (sex determining region Y)-box 3	0.027
FOLR3	folate receptor 3 (gamma)	0.027
C10orf95	chromosome 10 open reading frame 95	0.027
KLHL35	kelch-like 35 (Drosophila)	0.026
TH	tyrosine hydroxylase	0.025
GJA8	gap junction protein, alpha 8, 50kDa	0.025
CHRNG	cholinergic receptor, nicotinic, gamma	0.025
CNR2	cannabinoid receptor 2 (macrophage)	0.025
GRIA4	glutamate receptor, ionotrophic, AMPA 4	0.025
CYP11B2	cytochrome P450, family 11, subfamily B, polypeptide 2	0.024
MESP2	mesoderm posterior 2 homolog (mouse)	0.024
SLC7A4	solute carrier family 7 (cationic amino acid transporter, y+ system), member 4	0.024
CSHL1	chorionic somatomammotropin hormone-like 1	0.024
AIPL1	aryl hydrocarbon receptor interacting protein-like 1	0.023
CNGB1	cyclic nucleotide gated channel beta 1	0.023
ANXA10	annexin A10	0.022
CCL1	chemokine (C-C motif) ligand 1	0.022
P2RX2	purinergic receptor P2X, ligand-gated ion channel, 2	0.022
CLCNKB	chloride channel Kb	0.022
FUT5	fucosyltransferase 5 (alpha (1,3) fucosyltransferase)	0.022
GNAT2	guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2	0.021	Human
KLK2	kallikrein-related peptidase 2	0.021
S1PR2	sphingosine-1-phosphate receptor 2	0.020
KLK3	kallikrein-related peptidase 3	0.020
OR1E2	olfactory receptor, family 1, subfamily E, member 2	0.020
CABP2	calcium binding protein 2	0.020	Human
HTR3A	5-hydroxytryptamine (serotonin) receptor 3A	0.020
PRODH2	proline dehydrogenase (oxidase) 2	0.020
HSF2BP	heat shock transcription factor 2 binding protein	0.019
C15orf2	chromosome 15 open reading frame 2	0.019
C2orf51	chromosome 2 open reading frame 51	0.019
CCDC155	coiled-coil domain containing 155	0.019
RFPL3	ret finger protein-like 3	0.019
AQP2	aquaporin 2 (collecting duct)	0.019
TLX2	T-cell leukemia homeobox 2	0.018
AVPR1B	arginine vasopressin receptor 1B	0.018
OPN1SW	opsin 1 (cone pigments), short-wave-sensitive	0.018	Human
GCGR	glucagon receptor	0.018
COLEC10	collectin sub-family member 10 (C-type lectin)	0.018
CRP	C-reactive protein, pentraxin-related	0.018
PTGER1	prostaglandin E receptor 1 (subtype EP1), 42kDa	0.018
DEFA4	defensin, alpha 4, corticostatin	0.017
GUCA1A	guanylate cyclase activator 1A (retina)	0.017
SLC12A3	solute carrier family 12 (sodium/chloride transporters), member 3	0.017
KCNE1	potassium voltage-gated channel, Isk-related family, member 1	0.017
CD207	CD207 molecule, langerin	0.017
SLC45A2	solute carrier family 45, member 2	0.017
AZU1	azurocidin 1	0.017
SLC26A1	solute carrier family 26 (sulfate transporter), member 1	0.017
CYP2A6	cytochrome P450, family 2, subfamily A, polypeptide 6	0.017
LRRC50	leucine rich repeat containing 50	0.017
SLC4A1	solute carrier family 4, anion exchanger, member 1 (erythrocyte membrane protein band 3, Diego blood group)	0.017
GNB3	guanine nucleotide binding protein (G protein), beta polypeptide 3	0.016
MYT1	myelin transcription factor 1	0.016
KRT37	keratin 37	0.016
CLCN1	chloride channel 1, skeletal muscle	0.016
BPIL3	bactericidal/permeability-increasing protein-like 3	0.016
MAGEA12	melanoma antigen family A, 12	0.016
CRX	cone-rod homeobox	0.016
KRT3	keratin 3	0.016
CCIN	calicin	0.016
C7orf34	chromosome 7 open reading frame 34	0.016
UPK3A	uroplakin 3A	0.016
CD80	CD80 molecule	0.016
GRIK4	glutamate receptor, ionotropic, kainate 4	0.015
MAGEC2	melanoma antigen family C, 2	0.015
DUSP13	dual specificity phosphatase 13	0.015
QPCTL	glutaminyl-peptide cyclotransferase-like	0.015
FOXJ1	forkhead box J1	0.015
GNAO1	guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O	0.015	Human
POU4F3	POU class 4 homeobox 3	0.015
BTN1A1	butyrophilin, subfamily 1, member A1	0.015
SLC22A8	solute carrier family 22 (organic anion transporter), member 8	0.015
MLNR	motilin receptor	0.015
FAM5B	family with sequence similarity 5, member B	0.015
HAND1	heart and neural crest derivatives expressed 1	0.015
RTDR1	rhabdoid tumor deletion region gene 1	0.014
ACSM1	acyl-CoA synthetase medium-chain family member 1	0.014
CCDC38	coiled-coil domain containing 38	0.014
TMSB4Y	thymosin beta 4, Y-linked	0.014
TACR1	tachykinin receptor 1	0.014
GABRD	gamma-aminobutyric acid (GABA) A receptor, delta	0.014
BFSP2	beaded filament structural protein 2, phakinin	0.014
SLC22A1	solute carrier family 22 (organic cation transporter), member 1	0.014
GALR3	galanin receptor 3	0.014
MYL10	myosin, light chain 10, regulatory	0.014
SIX6	SIX homeobox 6	0.014
NHLH1	nescient helix loop helix 1	0.014
ERN2	endoplasmic reticulum to nucleus signaling 2	0.014
NR1I2	nuclear receptor subfamily 1, group I, member 2	0.014
CHRNA9	cholinergic receptor, nicotinic, alpha 9	0.014
GRIA1	glutamate receptor, ionotropic, AMPA 1	0.014
PDE6A	phosphodiesterase 6A, cGMP-specific, rod, alpha	0.014	Human
FBXO24	F-box protein 24	0.013
CALCA	calcitonin-related polypeptide alpha	0.013
CRYGC	crystallin, gamma C	0.013
MFSD6L	major facilitator superfamily domain containing 6-like	0.013
TNFRSF13C	tumor necrosis factor receptor superfamily, member 13C	0.013
APOBEC2	apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2	0.013
IL4	interleukin 4	0.013
ALPPL2	alkaline phosphatase, placental-like 2	0.013
S100A5	S100 calcium binding protein A5	0.013
SFTPD	surfactant protein D	0.013
DBH	dopamine beta-hydroxylase (dopamine beta-monooxygenase)	0.013
SPATA21	spermatogenesis associated 21	0.013
RDH8	retinol dehydrogenase 8 (all-trans)	0.013
LCT	lactase	0.013
KCNJ14	potassium inwardly-rectifying channel, subfamily J, member 14	0.013
TSPAN10	tetraspanin 10	0.013
ABCB11	ATP-binding cassette, sub-family B (MDR/TAP), member 11	0.013
LHX3	LIM homeobox 3	0.012
RAB3IL1	RAB3A interacting protein (rabin3)-like 1	0.012
GUCY2D	guanylate cyclase 2D, membrane (retina-specific)	0.012
MCHR1	melanin-concentrating hormone receptor 1	0.012
GHRHR	growth hormone releasing hormone receptor	0.012
TEKT2	tektin 2 (testicular)	0.012
TBX1	T-box 1	0.012
ALPI	alkaline phosphatase, intestinal	0.012
AFM	afamin	0.012
SSTR3	somatostatin receptor 3	0.012
CPNE6	copine VI (neuronal)	0.012
ATG9B	ATG9 autophagy related 9 homolog B (S. cerevisiae)	0.012
OR1G1	olfactory receptor, family 1, subfamily G, member 1	0.012
CRYBB2	crystallin, beta B2	0.012
CHRNA2	cholinergic receptor, nicotinic, alpha 2 (neuronal)	0.012
SLC6A7	solute carrier family 6 (neurotransmitter transporter, L-proline), member 7	0.012
PPIL6	peptidylprolyl isomerase (cyclophilin)-like 6	0.012
ATP8B3	ATPase, aminophospholipid transporter, class I, type 8B, member 3	0.012
TBX6	T-box 6	0.012
PRAMEF12	PRAME family member 12	0.012
MYLPF	myosin light chain, phosphorylatable, fast skeletal muscle	0.012
GCM1	glial cells missing homolog 1 (Drosophila)	0.012
BTNL3	butyrophilin-like 3	0.012
KRT2	keratin 2	0.012
SLC22A13	solute carrier family 22 (organic anion transporter), member 13	0.012
SFTPB	surfactant protein B	0.012
NGB	neuroglobin	0.012
TBL1Y	transducin (beta)-like 1, Y-linked	0.012
SLC5A5	solute carrier family 5 (sodium iodide symporter), member 5	0.011
FZD9	frizzled homolog 9 (Drosophila)	0.011
UNC119	unc-119 homolog (C. elegans)	0.011
GPR182	G protein-coupled receptor 182	0.011
PMEL	premelanosome protein	0.011
ZNF771	zinc finger protein 771	0.011
SHH	sonic hedgehog	0.011
SARDH	sarcosine dehydrogenase	0.011
OSBP2	oxysterol binding protein 2	0.011
NEUROD2	neurogenic differentiation 2	0.011
CYLC1	cylicin, basic protein of sperm head cytoskeleton 1	0.011
LOR	loricrin	0.011
WNT10B	wingless-type MMTV integration site family, member 10B	0.011
FUT1	fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group)	0.011
CYP17A1	cytochrome P450, family 17, subfamily A, polypeptide 1	0.011
NYX	nyctalopin	0.011
MIOX	myo-inositol oxygenase	0.011
PLA2G2E	phospholipase A2, group IIE	0.011
HNF1B	HNF1 homeobox B	0.011
GRM2	glutamate receptor, metabotropic 2	0.011	Human
OR7A10	olfactory receptor, family 7, subfamily A, member 10	0.010
TRPV5	transient receptor potential cation channel, subfamily V, member 5	0.010
LIM2	lens intrinsic membrane protein 2, 19kDa	0.010
CADM4	cell adhesion molecule 4	0.010
MC4R	melanocortin 4 receptor	0.010
LTK	leukocyte receptor tyrosine kinase	0.010
TSKS	testis-specific serine kinase substrate	0.010
DNASE1L2	deoxyribonuclease I-like 2	0.010
GABRA4	gamma-aminobutyric acid (GABA) A receptor, alpha 4	0.010
RNF151	ring finger protein 151	0.010
EDAR	ectodysplasin A receptor	0.010
MAGEB4	melanoma antigen family B, 4	0.010
PDE6B	phosphodiesterase 6B, cGMP-specific, rod, beta	0.008
TRPM1	transient receptor potential cation channel, subfamily M, member 1	0.005
GRM6	glutamate receptor, metabotropic 6	0.002