Homo sapiens

27 known processes

TDG

thymine-DNA glycosylase

TDG biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
determination of adult lifespan GO:0008340 2 0.693
cellular response to dna damage stimulus GO:0006974 379 0.609
multicellular organismal aging GO:0010259 3 0.443
positive regulation of developmental process GO:0051094 314 0.339
nucleoside monophosphate metabolic process GO:0009123 191 0.268
purine nucleotide catabolic process GO:0006195 405 0.256
purine nucleoside triphosphate metabolic process GO:0009144 412 0.244
response to abiotic stimulus GO:0009628 336 0.231
glycosyl compound catabolic process GO:1901658 413 0.219
organophosphate catabolic process GO:0046434 430 0.204
purine nucleoside triphosphate catabolic process GO:0009146 392 0.185
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.172
ribonucleoprotein complex biogenesis GO:0022613 116 0.144
nucleoside phosphate catabolic process GO:1901292 412 0.143
ubiquitin dependent protein catabolic process GO:0006511 206 0.138
ribonucleoside triphosphate metabolic process GO:0009199 412 0.138
regulation of cellular response to stress GO:0080135 244 0.126
viral process GO:0016032 146 0.125
regulation of cell cycle GO:0051726 393 0.124
purine ribonucleotide catabolic process GO:0009154 404 0.121
cell cycle phase transition GO:0044770 173 0.112
regulation of dna metabolic process GO:0051052 153 0.111
embryo development GO:0009790 123 0.107
purine ribonucleoside metabolic process GO:0046128 437 0.104
ossification GO:0001503 121 0.104
nucleoside catabolic process GO:0009164 408 0.103
purine ribonucleoside catabolic process GO:0046130 398 0.102
regulation of response to external stimulus GO:0032101 222 0.102
organophosphate biosynthetic process GO:0090407 163 0.099
mrna processing GO:0006397 133 0.098
ribonucleoside triphosphate catabolic process GO:0009203 391 0.092
g2 dna damage checkpoint GO:0031572 26 0.089
enzyme linked receptor protein signaling pathway GO:0007167 303 0.088
negative regulation of multicellular organismal process GO:0051241 317 0.087
negative regulation of binding GO:0051100 57 0.087
dna repair GO:0006281 198 0.086
cell cycle checkpoint GO:0000075 117 0.085
neurogenesis GO:0022008 169 0.085
dna damage checkpoint GO:0000077 68 0.085
ncrna metabolic process GO:0034660 108 0.084
cellular protein catabolic process GO:0044257 261 0.084
oogenesis GO:0048477 2 0.084
posttranscriptional regulation of gene expression GO:0010608 213 0.079
protein modification by small protein conjugation GO:0032446 342 0.077
response to transforming growth factor beta GO:0071559 94 0.077
ribonucleoside catabolic process GO:0042454 406 0.075
protein ubiquitination GO:0016567 314 0.074
post embryonic development GO:0009791 2 0.073
cellular response to transforming growth factor beta stimulus GO:0071560 94 0.071
dna integrity checkpoint GO:0031570 71 0.070
osteoblast differentiation GO:0001649 92 0.070
purine nucleoside monophosphate metabolic process GO:0009126 186 0.068
signal transduction by phosphorylation GO:0023014 297 0.067
nucleoside triphosphate metabolic process GO:0009141 422 0.063
locomotory behavior GO:0007626 1 0.062
nervous system development GO:0007399 293 0.062
ribonucleoside monophosphate metabolic process GO:0009161 187 0.062
carbohydrate derivative biosynthetic process GO:1901137 207 0.061
positive regulation of catabolic process GO:0009896 310 0.058
purine containing compound catabolic process GO:0072523 411 0.057
regulation of viral process GO:0050792 103 0.057
blood vessel morphogenesis GO:0048514 162 0.057
regulation of binding GO:0051098 111 0.057
cell development GO:0048468 328 0.057
negative regulation of cellular protein metabolic process GO:0032269 353 0.056
response to biotic stimulus GO:0009607 276 0.054
chromatin modification GO:0016568 298 0.053
positive regulation of hydrolase activity GO:0051345 331 0.053
microtubule cytoskeleton organization GO:0000226 176 0.052
negative regulation of toll signaling pathway GO:0045751 1 0.051
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.050
atp metabolic process GO:0046034 176 0.050
rrna metabolic process GO:0016072 40 0.049
protein catabolic process GO:0030163 325 0.048
female gamete generation GO:0007292 2 0.048
chromosome segregation GO:0007059 114 0.048
regulation of angiogenesis GO:0045765 92 0.047
mitotic cell cycle phase transition GO:0044772 162 0.046
aging GO:0007568 66 0.046
cellular response to growth factor stimulus GO:0071363 197 0.046
negative regulation of cell cycle GO:0045786 193 0.045
regulation of vasculature development GO:1901342 97 0.045
negative regulation of protein modification process GO:0031400 200 0.044
jnk cascade GO:0007254 80 0.044
regulation of nucleotide metabolic process GO:0006140 269 0.043
nucleoside monophosphate catabolic process GO:0009125 159 0.042
neuron differentiation GO:0030182 138 0.041
modification dependent protein catabolic process GO:0019941 209 0.041
microtubule based process GO:0007017 210 0.041
epithelium migration GO:0090132 119 0.040
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.039
organonitrogen compound biosynthetic process GO:1901566 200 0.039
ncrna processing GO:0034470 83 0.039
regulation of mitotic cell cycle GO:0007346 189 0.039
neuromuscular junction development GO:0007528 3 0.038
angiogenesis GO:0001525 147 0.038
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 125 0.038
positive regulation of cell differentiation GO:0045597 211 0.038
ribonucleotide catabolic process GO:0009261 405 0.037
cell morphogenesis involved in differentiation GO:0000904 144 0.037
regulation of purine nucleotide catabolic process GO:0033121 205 0.037
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.036
transcription elongation from rna polymerase ii promoter GO:0006368 18 0.035
response to radiation GO:0009314 151 0.035
guanosine containing compound metabolic process GO:1901068 244 0.035
mapk cascade GO:0000165 288 0.035
mitotic cell cycle process GO:1903047 286 0.035
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.034
negative regulation of locomotion GO:0040013 118 0.034
hematopoietic or lymphoid organ development GO:0048534 186 0.034
stress activated mapk cascade GO:0051403 93 0.033
maintenance of location GO:0051235 112 0.033
meiotic chromosome segregation GO:0045132 4 0.033
antimicrobial humoral response GO:0019730 26 0.033
regulation of protein serine threonine kinase activity GO:0071900 179 0.033
humoral immune response GO:0006959 49 0.032
nucleoside triphosphate catabolic process GO:0009143 394 0.032
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 50 0.031
purine containing compound biosynthetic process GO:0072522 88 0.031
chromatin organization GO:0006325 351 0.031
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.030
interspecies interaction between organisms GO:0044419 156 0.030
regulation of purine nucleotide metabolic process GO:1900542 264 0.030
regulation of proteasomal protein catabolic process GO:0061136 87 0.030
protein localization to organelle GO:0033365 280 0.030
rna processing GO:0006396 255 0.030
cell morphogenesis GO:0000902 296 0.030
signal transduction by p53 class mediator GO:0072331 72 0.030
regulation of mitotic cell cycle phase transition GO:1901990 118 0.030
nucleotide biosynthetic process GO:0009165 109 0.029
maturation of lsu rrna GO:0000470 3 0.029
ribonucleoside monophosphate catabolic process GO:0009158 158 0.029
nucleotide catabolic process GO:0009166 408 0.029
cellular protein complex assembly GO:0043623 188 0.028
positive regulation of i kappab kinase nf kappab signaling GO:0043123 132 0.028
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.028
negative regulation of mitotic cell cycle phase transition GO:1901991 85 0.028
negative regulation of cell cycle phase transition GO:1901988 89 0.027
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.027
regulation of cellular component biogenesis GO:0044087 281 0.026
positive regulation of cysteine type endopeptidase activity GO:2001056 79 0.026
negative regulation of protein metabolic process GO:0051248 391 0.026
cellular response to endogenous stimulus GO:0071495 336 0.026
dna conformation change GO:0071103 113 0.026
proteasomal protein catabolic process GO:0010498 176 0.025
associative learning GO:0008306 1 0.025
negative regulation of catalytic activity GO:0043086 335 0.025
cellular amine metabolic process GO:0044106 41 0.025
mitotic nuclear division GO:0007067 119 0.025
purine ribonucleotide biosynthetic process GO:0009152 79 0.025
negative regulation of cell proliferation GO:0008285 228 0.025
cell adhesion GO:0007155 325 0.025
regulation of stress activated mapk cascade GO:0032872 84 0.025
positive regulation of multi organism process GO:0043902 56 0.024
regulation of cell cycle phase transition GO:1901987 126 0.024
zymogen activation GO:0031638 70 0.024
peripheral nervous system development GO:0007422 2 0.024
cellular component morphogenesis GO:0032989 314 0.024
cell fate determination GO:0001709 3 0.024
cytoplasmic transport GO:0016482 379 0.024
regulation of cell differentiation GO:0045595 393 0.024
camera type eye development GO:0043010 25 0.024
growth GO:0040007 202 0.024
tissue migration GO:0090130 119 0.024
regulation of dna binding GO:0051101 37 0.023
regulation of cellular response to growth factor stimulus GO:0090287 76 0.023
dna replication GO:0006260 116 0.023
macromolecule methylation GO:0043414 97 0.023
dna dependent dna replication GO:0006261 44 0.023
ribosome biogenesis GO:0042254 48 0.023
pharynx development GO:0060465 1 0.023
vesicle mediated transport GO:0016192 371 0.022
intracellular protein transport GO:0006886 270 0.022
mitotic cell cycle GO:0000278 326 0.022
regulation of viral transcription GO:0046782 34 0.022
regulation of cellular amine metabolic process GO:0033238 11 0.022
regulation of locomotion GO:0040012 329 0.022
somitogenesis GO:0001756 2 0.022
response to wounding GO:0009611 168 0.022
positive regulation of developmental growth GO:0048639 16 0.022
response to growth factor GO:0070848 205 0.022
activation of cysteine type endopeptidase activity GO:0097202 57 0.021
regulation of cell cycle process GO:0010564 266 0.021
protein maturation GO:0051604 233 0.021
purine nucleoside monophosphate catabolic process GO:0009128 158 0.021
negative regulation of cell migration GO:0030336 102 0.020
regulation of osteoblast differentiation GO:0045667 38 0.020
translation GO:0006412 132 0.020
rna phosphodiester bond hydrolysis GO:0090501 35 0.020
generation of neurons GO:0048699 152 0.020
positive regulation of response to dna damage stimulus GO:2001022 43 0.020
blood vessel development GO:0001568 172 0.020
negative regulation of developmental process GO:0051093 247 0.020
muscle organ development GO:0007517 56 0.020
amine metabolic process GO:0009308 44 0.020
lipid localization GO:0010876 106 0.020
regulation of nucleoside metabolic process GO:0009118 209 0.020
regulation of endopeptidase activity GO:0052548 170 0.020
positive regulation of nucleotide catabolic process GO:0030813 185 0.019
erythrocyte differentiation GO:0030218 28 0.019
cellular macromolecular complex assembly GO:0034622 324 0.019
regulation of protein stability GO:0031647 87 0.019
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.019
myoblast fusion GO:0007520 1 0.019
single organism cellular localization GO:1902580 332 0.019
mitotic cell cycle checkpoint GO:0007093 68 0.019
mitotic dna integrity checkpoint GO:0044774 30 0.019
retina development in camera type eye GO:0060041 15 0.019
histone modification GO:0016570 251 0.018
ribonucleotide biosynthetic process GO:0009260 81 0.018
positive regulation of cellular catabolic process GO:0031331 284 0.018
endocytosis GO:0006897 159 0.018
rna splicing via transesterification reactions GO:0000375 90 0.018
positive regulation of cellular component biogenesis GO:0044089 158 0.018
modification dependent macromolecule catabolic process GO:0043632 212 0.018
positive regulation of nucleoside metabolic process GO:0045979 186 0.018
cardiovascular system development GO:0072358 262 0.018
positive regulation of extrinsic apoptotic signaling pathway via death domain receptors GO:1902043 3 0.018
embryo development ending in birth or egg hatching GO:0009792 34 0.018
nuclear division GO:0000280 128 0.018
positive regulation of nucleotide metabolic process GO:0045981 230 0.018
extrinsic apoptotic signaling pathway GO:0097191 119 0.017
spermatid differentiation GO:0048515 4 0.017
ameboidal type cell migration GO:0001667 135 0.017
regulation of growth GO:0040008 165 0.017
regulation of protein catabolic process GO:0042176 155 0.017
cellular macromolecule catabolic process GO:0044265 380 0.017
guanosine containing compound catabolic process GO:1901069 239 0.017
developmental process involved in reproduction GO:0003006 66 0.017
chromatin assembly or disassembly GO:0006333 78 0.016
protein dna complex subunit organization GO:0071824 80 0.016
negative regulation of dna binding GO:0043392 18 0.016
regulation of anatomical structure morphogenesis GO:0022603 286 0.016
regulation of response to dna damage stimulus GO:2001020 94 0.016
multi organism metabolic process GO:0044033 41 0.016
single organism reproductive process GO:0044702 98 0.016
memory GO:0007613 3 0.016
viral life cycle GO:0019058 132 0.016
phospholipid metabolic process GO:0006644 99 0.016
positive regulation of cell development GO:0010720 92 0.016
protein modification by small protein removal GO:0070646 92 0.016
ribose phosphate biosynthetic process GO:0046390 82 0.015
definitive hemopoiesis GO:0060216 2 0.015
negative regulation of protein processing GO:0010955 142 0.015
methylation GO:0032259 106 0.015
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 90 0.015
eye development GO:0001654 42 0.015
positive regulation of programmed cell death GO:0043068 249 0.015
regulation of multicellular organism growth GO:0040014 8 0.015
anatomical structure homeostasis GO:0060249 100 0.015
vasculature development GO:0001944 181 0.015
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.015
gastrulation with mouth forming second GO:0001702 1 0.015
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.015
positive regulation of cell death GO:0010942 263 0.015
system process GO:0003008 349 0.015
organ morphogenesis GO:0009887 147 0.015
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 131 0.015
immune response GO:0006955 307 0.015
regulation of dna replication GO:0006275 68 0.014
regulation of chromosome organization GO:0033044 103 0.014
regulation of transferase activity GO:0051338 355 0.014
pattern specification process GO:0007389 43 0.014
developmental growth GO:0048589 48 0.014
response to hypoxia GO:0001666 96 0.014
carbohydrate metabolic process GO:0005975 207 0.014
response to external biotic stimulus GO:0043207 261 0.014
spermatid development GO:0007286 4 0.014
regulation of multi organism process GO:0043900 157 0.014
embryonic placenta development GO:0001892 1 0.014
homeostasis of number of cells GO:0048872 40 0.014
regulation of cellular component movement GO:0051270 334 0.014
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 89 0.014
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 109 0.014
regulation of nucleotide catabolic process GO:0030811 205 0.014
cell projection organization GO:0030030 252 0.014
central nervous system development GO:0007417 123 0.014
response to tumor necrosis factor GO:0034612 76 0.014
regulation of cellular amino acid metabolic process GO:0006521 6 0.014
tube development GO:0035295 125 0.014
regulation of map kinase activity GO:0043405 108 0.014
transforming growth factor beta receptor signaling pathway GO:0007179 76 0.014
positive regulation of mapk cascade GO:0043410 190 0.014
protein sumoylation GO:0016925 25 0.014
regulation of ossification GO:0030278 58 0.013
negative regulation of cellular component organization GO:0051129 235 0.013
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.013
hemopoiesis GO:0030097 180 0.013
regulation of protein complex assembly GO:0043254 147 0.013
negative regulation of protein phosphorylation GO:0001933 140 0.013
muscle contraction GO:0006936 73 0.013
regulation of transforming growth factor beta receptor signaling pathway GO:0017015 48 0.013
anatomical structure formation involved in morphogenesis GO:0048646 284 0.013
regulation of stress activated protein kinase signaling cascade GO:0070302 85 0.013
regulation of proteolysis GO:0030162 293 0.013
visual behavior GO:0007632 2 0.013
positive regulation of neurogenesis GO:0050769 49 0.013
stem cell differentiation GO:0048863 93 0.013
neuron projection development GO:0031175 106 0.013
regulation of ubiquitin protein transferase activity GO:0051438 28 0.013
response to light stimulus GO:0009416 87 0.013
glycoprotein biosynthetic process GO:0009101 91 0.013
regulation of response to wounding GO:1903034 101 0.013
syncytium formation by plasma membrane fusion GO:0000768 2 0.013
rna interference GO:0016246 4 0.013
protein targeting GO:0006605 187 0.012
cellular component disassembly GO:0022411 92 0.012
regulation of protein localization GO:0032880 296 0.012
response to other organism GO:0051707 261 0.012
activation of cysteine type endopeptidase activity involved in apoptotic process GO:0006919 49 0.012
spinal cord development GO:0021510 4 0.012
stress activated protein kinase signaling cascade GO:0031098 94 0.012
actin filament based process GO:0030029 224 0.012
short term memory GO:0007614 1 0.012
regulation of neural precursor cell proliferation GO:2000177 4 0.012
cell part morphogenesis GO:0032990 137 0.012
regulation of nucleocytoplasmic transport GO:0046822 98 0.012
positive regulation of gtp catabolic process GO:0033126 166 0.012
maturation of ssu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna GO:0000462 1 0.012
multi organism cellular process GO:0044764 156 0.012
response to activity GO:0014823 0 0.012
actin cytoskeleton organization GO:0030036 207 0.012
cardiac muscle cell contraction GO:0086003 4 0.012
sex differentiation GO:0007548 45 0.012
epithelium development GO:0060429 227 0.012
protein methylation GO:0006479 74 0.012
oocyte differentiation GO:0009994 2 0.012
negative regulation of intracellular steroid hormone receptor signaling pathway GO:0033144 18 0.012
positive regulation of nervous system development GO:0051962 54 0.012
response to nutrient levels GO:0031667 81 0.012
atp catabolic process GO:0006200 157 0.012
cellular amino acid metabolic process GO:0006520 116 0.012
gtp metabolic process GO:0046039 239 0.012
positive regulation of apoptotic signaling pathway GO:2001235 70 0.011
dephosphorylation GO:0016311 209 0.011
negative regulation of protein ubiquitination GO:0031397 35 0.011
cell type specific apoptotic process GO:0097285 125 0.011
rna splicing GO:0008380 131 0.011
embryonic morphogenesis GO:0048598 85 0.011
multicellular organismal reproductive process GO:0048609 40 0.011
regulation of extrinsic apoptotic signaling pathway GO:2001236 85 0.011
regulation of peptidase activity GO:0052547 180 0.011
ras protein signal transduction GO:0007265 73 0.011
regulation of meiotic cell cycle GO:0051445 4 0.011
multicellular organismal signaling GO:0035637 34 0.011
purine nucleoside catabolic process GO:0006152 398 0.011
reproductive system development GO:0061458 56 0.011
hemoglobin metabolic process GO:0020027 3 0.011
reproduction GO:0000003 63 0.011
multicellular organism reproduction GO:0032504 42 0.011
regulation of neurogenesis GO:0050767 82 0.011
protein stabilization GO:0050821 64 0.011
development of primary sexual characteristics GO:0045137 35 0.011
toll signaling pathway GO:0008063 2 0.011
receptor mediated endocytosis GO:0006898 84 0.011
protein processing GO:0016485 226 0.011
viral gene expression GO:0019080 35 0.011
negative regulation of cell cycle process GO:0010948 121 0.011
regulation of protein kinase activity GO:0045859 289 0.011
circulatory system process GO:0003013 113 0.011
visual learning GO:0008542 1 0.011
single organism carbohydrate metabolic process GO:0044723 193 0.011
striated muscle contraction GO:0006941 52 0.011
regulation of dna templated transcription elongation GO:0032784 23 0.010
regulation of nervous system development GO:0051960 88 0.010
peptidyl threonine modification GO:0018210 45 0.010
histone exchange GO:0043486 3 0.010
negative regulation of phosphate metabolic process GO:0045936 267 0.010
response to organic cyclic compound GO:0014070 204 0.010
regulation of cysteine type endopeptidase activity GO:2000116 127 0.010
regulation of kinase activity GO:0043549 314 0.010
innate immune response GO:0045087 178 0.010
positive regulation of proteolysis GO:0045862 142 0.010
gland development GO:0048732 48 0.010
dna templated transcription initiation GO:0006352 35 0.010

TDG disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 295 0.017
inherited metabolic disorder DOID:655 242 0.014
disease of cellular proliferation DOID:14566 174 0.013
cancer DOID:162 167 0.013