|
|
positive regulation of odontogenesis
|
GO:0042482 |
3 |
1.000
|
|
|
|
pattern specification involved in kidney development
|
GO:0061004 |
1 |
1.000
|
|
|
|
renal system pattern specification
|
GO:0072048 |
1 |
1.000
|
|
|
|
regulation of branching involved in ureteric bud morphogenesis
|
GO:0090189 |
3 |
1.000
|
|
|
|
positive regulation of pathway restricted smad protein phosphorylation
|
GO:0010862 |
22 |
1.000
|
|
|
|
positive regulation of cardioblast differentiation
|
GO:0051891 |
2 |
1.000
|
|
|
|
regulation of odontogenesis
|
GO:0042481 |
4 |
1.000
|
|
|
|
bmp signaling pathway involved in heart development
|
GO:0061312 |
3 |
0.999
|
|
|
|
regulation of activin receptor signaling pathway
|
GO:0032925 |
14 |
0.997
|
Human |
|
|
cardiac epithelial to mesenchymal transition
|
GO:0060317 |
3 |
0.992
|
|
|
|
mesenchymal to epithelial transition involved in metanephros morphogenesis
|
GO:0003337 |
4 |
0.992
|
|
|
|
regulation of pathway restricted smad protein phosphorylation
|
GO:0060393 |
34 |
0.992
|
|
|
|
regulation of smooth muscle cell differentiation
|
GO:0051150 |
3 |
0.990
|
|
|
|
pathway restricted smad protein phosphorylation
|
GO:0060389 |
38 |
0.986
|
|
|
|
negative regulation of cardiac muscle tissue development
|
GO:0055026 |
7 |
0.985
|
|
|
|
endodermal mesodermal cell signaling
|
GO:0003133 |
3 |
0.984
|
|
|
|
regulation of smad protein import into nucleus
|
GO:0060390 |
10 |
0.976
|
|
|
|
atrial septum primum morphogenesis
|
GO:0003289 |
1 |
0.969
|
|
|
|
branch elongation of an epithelium
|
GO:0060602 |
3 |
0.969
|
|
|
|
regulation of glomerulus development
|
GO:0090192 |
3 |
0.968
|
|
|
|
mitral valve development
|
GO:0003174 |
3 |
0.967
|
|
|
|
negative regulation of cardiac muscle cell differentiation
|
GO:2000726 |
3 |
0.963
|
|
|
|
positive regulation of hair follicle maturation
|
GO:0048818 |
2 |
0.963
|
|
|
|
regulation of aldosterone biosynthetic process
|
GO:0032347 |
6 |
0.959
|
|
|
|
endocardial cushion development
|
GO:0003197 |
3 |
0.955
|
|
|
|
negative regulation of kidney development
|
GO:0090185 |
2 |
0.955
|
|
|
|
negative regulation of trophoblast cell migration
|
GO:1901164 |
3 |
0.951
|
|
|
|
forebrain regionalization
|
GO:0021871 |
3 |
0.948
|
|
|
|
determination of dorsal ventral asymmetry
|
GO:0048262 |
4 |
0.948
|
|
|
|
negative regulation of macrophage cytokine production
|
GO:0010936 |
3 |
0.947
|
|
|
|
common partner smad protein phosphorylation
|
GO:0007182 |
3 |
0.944
|
|
|
|
branch elongation involved in ureteric bud branching
|
GO:0060681 |
2 |
0.940
|
|
|
|
negative regulation of chorionic trophoblast cell proliferation
|
GO:1901383 |
2 |
0.936
|
|
|
|
nephric duct formation
|
GO:0072179 |
1 |
0.935
|
|
|
|
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090101 |
45 |
0.933
|
Human |
|
|
negative regulation of glomerulus development
|
GO:0090194 |
2 |
0.922
|
|
|
|
calcium independent cell cell adhesion via plasma membrane cell adhesion molecules
|
GO:0016338 |
2 |
0.910
|
|
|
|
regulation of striated muscle tissue development
|
GO:0016202 |
26 |
0.908
|
|
|
|
regulation of bone mineralization
|
GO:0030500 |
29 |
0.901
|
|
|
|
negative regulation of glucocorticoid biosynthetic process
|
GO:0031947 |
4 |
0.901
|
|
|
|
negative regulation of muscle organ development
|
GO:0048635 |
12 |
0.896
|
|
|
|
positive regulation of ossification
|
GO:0045778 |
32 |
0.893
|
|
|
|
renal tubule development
|
GO:0061326 |
19 |
0.881
|
|
|
|
positive regulation of stem cell differentiation
|
GO:2000738 |
29 |
0.881
|
|
|
|
negative regulation of chondrocyte proliferation
|
GO:1902731 |
1 |
0.881
|
|
|
|
atrioventricular valve development
|
GO:0003171 |
3 |
0.878
|
|
|
|
nephron tubule morphogenesis
|
GO:0072078 |
13 |
0.876
|
|
|
|
regulation of biomineral tissue development
|
GO:0070167 |
31 |
0.876
|
|
|
|
mesenchyme development
|
GO:0060485 |
59 |
0.874
|
|
|
|
positive regulation of biomineral tissue development
|
GO:0070169 |
20 |
0.874
|
|
|
|
positive regulation of epithelial to mesenchymal transition
|
GO:0010718 |
22 |
0.873
|
|
|
|
determination of dorsal identity
|
GO:0048263 |
4 |
0.871
|
|
|
|
negative regulation of steroid hormone biosynthetic process
|
GO:0090032 |
4 |
0.870
|
|
|
|
inner ear morphogenesis
|
GO:0042472 |
4 |
0.865
|
|
|
|
ureteric bud elongation
|
GO:0060677 |
2 |
0.854
|
|
|
|
negative regulation of gastrulation
|
GO:2000542 |
4 |
0.847
|
|
|
|
craniofacial suture morphogenesis
|
GO:0097094 |
3 |
0.845
|
|
|
|
cardiac muscle cell fate commitment
|
GO:0060923 |
4 |
0.839
|
|
|
|
atrioventricular valve morphogenesis
|
GO:0003181 |
2 |
0.826
|
|
|
|
regulation of multicellular organismal metabolic process
|
GO:0044246 |
17 |
0.824
|
|
|
|
heart morphogenesis
|
GO:0003007 |
48 |
0.823
|
|
|
|
endocardial cell fate commitment
|
GO:0060957 |
1 |
0.822
|
|
|
|
regulation of mesonephros development
|
GO:0061217 |
3 |
0.818
|
|
|
|
positive regulation of endothelial cell migration
|
GO:0010595 |
39 |
0.818
|
|
|
|
bone mineralization
|
GO:0030282 |
34 |
0.813
|
|
|
|
cardiac muscle tissue development
|
GO:0048738 |
39 |
0.801
|
|
|
|
biomineral tissue development
|
GO:0031214 |
39 |
0.799
|
|
|
|
specification of organ identity
|
GO:0010092 |
3 |
0.795
|
|
|
|
mesenchymal cell development
|
GO:0014031 |
50 |
0.788
|
|
|
|
axis elongation
|
GO:0003401 |
4 |
0.785
|
|
|
|
activation of protein kinase activity
|
GO:0032147 |
90 |
0.773
|
|
|
|
negative regulation of mesonephros development
|
GO:0061218 |
1 |
0.770
|
|
|
|
ureteric bud morphogenesis
|
GO:0060675 |
10 |
0.767
|
|
|
|
negative regulation of skeletal muscle tissue development
|
GO:0048642 |
2 |
0.764
|
|
|
|
negative regulation of glomerular mesangial cell proliferation
|
GO:0072125 |
2 |
0.763
|
|
|
|
bmp signaling pathway involved in heart induction
|
GO:0003130 |
3 |
0.761
|
|
|
|
endodermal mesodermal cell signaling involved in heart induction
|
GO:0003134 |
3 |
0.760
|
|
|
|
positive regulation of mesonephros development
|
GO:0061213 |
2 |
0.760
|
|
|
|
positive regulation of trophoblast cell migration
|
GO:1901165 |
2 |
0.752
|
|
|
|
regulation of epithelial to mesenchymal transition
|
GO:0010717 |
37 |
0.751
|
|
|
|
regulation of stem cell differentiation
|
GO:2000736 |
56 |
0.748
|
|
|
|
lung alveolus development
|
GO:0048286 |
4 |
0.747
|
|
|
|
regulation of collagen metabolic process
|
GO:0010712 |
15 |
0.739
|
|
|
|
pituitary gland development
|
GO:0021983 |
2 |
0.738
|
|
|
|
chondrocyte development
|
GO:0002063 |
1 |
0.732
|
|
|
|
positive regulation of protein transport
|
GO:0051222 |
135 |
0.717
|
|
|
|
regulation of myoblast differentiation
|
GO:0045661 |
12 |
0.715
|
|
|
|
ureter development
|
GO:0072189 |
3 |
0.714
|
|
|
|
regulation of endodermal cell differentiation
|
GO:1903224 |
3 |
0.706
|
|
|
|
kidney morphogenesis
|
GO:0060993 |
19 |
0.705
|
|
|
|
positive regulation of branching involved in ureteric bud morphogenesis
|
GO:0090190 |
2 |
0.704
|
|
|
|
chorionic trophoblast cell proliferation
|
GO:0097360 |
2 |
0.696
|
|
|
|
regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090092 |
90 |
0.688
|
Human Zebrafish |
|
|
positive regulation of map kinase activity
|
GO:0043406 |
80 |
0.686
|
|
|
|
atrial septum morphogenesis
|
GO:0060413 |
5 |
0.681
|
|
|
|
positive regulation of locomotion
|
GO:0040017 |
186 |
0.681
|
|
|
|
negative regulation of endodermal cell differentiation
|
GO:1903225 |
2 |
0.675
|
|
|
|
epithelial to mesenchymal transition
|
GO:0001837 |
48 |
0.668
|
|
|
|
regulation of muscle organ development
|
GO:0048634 |
27 |
0.667
|
|
|
|
odontogenesis
|
GO:0042476 |
25 |
0.660
|
|
|
|
nephron morphogenesis
|
GO:0072028 |
15 |
0.659
|
|
|
|
skeletal system development
|
GO:0001501 |
79 |
0.658
|
|
|
|
regulation of endothelial cell migration
|
GO:0010594 |
67 |
0.652
|
|
|
|
negative regulation of striated muscle tissue development
|
GO:0045843 |
11 |
0.650
|
|
|
|
regulation of muscle tissue development
|
GO:1901861 |
26 |
0.644
|
|
|
|
regulation of epithelial cell migration
|
GO:0010632 |
93 |
0.640
|
|
|
|
positive regulation of smad protein import into nucleus
|
GO:0060391 |
8 |
0.629
|
|
|
|
positive regulation of cell morphogenesis involved in differentiation
|
GO:0010770 |
50 |
0.627
|
|
|
|
nephric duct morphogenesis
|
GO:0072178 |
1 |
0.624
|
|
|
|
heart formation
|
GO:0060914 |
2 |
0.624
|
|
|
|
biological adhesion
|
GO:0022610 |
331 |
0.621
|
Human |
|
|
positive regulation of bone mineralization
|
GO:0030501 |
19 |
0.619
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.614
|
|
|
|
positive regulation of osteoblast differentiation
|
GO:0045669 |
23 |
0.606
|
|
|
|
glomerular mesangial cell proliferation
|
GO:0072110 |
3 |
0.606
|
|
|
|
renal vesicle development
|
GO:0072087 |
4 |
0.602
|
|
|
|
bone development
|
GO:0060348 |
26 |
0.601
|
|
|
|
activation of mapk activity
|
GO:0000187 |
45 |
0.600
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.597
|
Human Zebrafish |
|
|
mineralocorticoid metabolic process
|
GO:0008212 |
9 |
0.595
|
|
|
|
multicellular organismal metabolic process
|
GO:0044236 |
34 |
0.590
|
|
|
|
negative regulation of muscle cell differentiation
|
GO:0051148 |
17 |
0.585
|
|
|
|
positive regulation of catagen
|
GO:0051795 |
2 |
0.578
|
|
|
|
stem cell development
|
GO:0048864 |
69 |
0.560
|
|
|
|
regulation of cardioblast differentiation
|
GO:0051890 |
4 |
0.560
|
|
|
|
aldosterone metabolic process
|
GO:0032341 |
9 |
0.557
|
|
|
|
positive regulation of isotype switching to iga isotypes
|
GO:0048298 |
2 |
0.556
|
|
|
|
endocardial cushion cell differentiation
|
GO:0061443 |
1 |
0.555
|
|
|
|
s shaped body morphogenesis
|
GO:0072050 |
4 |
0.553
|
|
|
|
endoderm development
|
GO:0007492 |
33 |
0.552
|
|
|
|
negative regulation of muscle tissue development
|
GO:1901862 |
11 |
0.551
|
|
|
|
patterning of blood vessels
|
GO:0001569 |
2 |
0.543
|
|
|
|
organ formation
|
GO:0048645 |
3 |
0.540
|
|
|
|
secondary heart field specification
|
GO:0003139 |
2 |
0.538
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.537
|
|
|
|
cortisol biosynthetic process
|
GO:0034651 |
8 |
0.534
|
|
|
|
mesenchymal cell differentiation
|
GO:0048762 |
52 |
0.531
|
|
|
|
positive regulation of transcription from rna polymerase ii promoter involved in cellular response to chemical stimulus
|
GO:1901522 |
2 |
0.522
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.521
|
|
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.515
|
|
|
|
neuroendocrine cell differentiation
|
GO:0061101 |
2 |
0.508
|
|
|
|
regulation of cell proliferation involved in kidney development
|
GO:1901722 |
3 |
0.506
|
|
|
|
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090100 |
41 |
0.499
|
|
|
|
negative regulation of cell adhesion
|
GO:0007162 |
64 |
0.496
|
|
|
|
positive regulation of multicellular organismal metabolic process
|
GO:0044253 |
11 |
0.495
|
|
|
|
positive regulation of epithelial cell migration
|
GO:0010634 |
55 |
0.493
|
|
|
|
renal tubule morphogenesis
|
GO:0061333 |
14 |
0.492
|
|
|
|
epithelial cell proliferation involved in lung morphogenesis
|
GO:0060502 |
3 |
0.491
|
|
|
|
muscle cell proliferation
|
GO:0033002 |
35 |
0.481
|
|
|
|
endocardial cell differentiation
|
GO:0060956 |
2 |
0.479
|
|
|
|
muscle tissue development
|
GO:0060537 |
62 |
0.479
|
|
|
|
regulation of ossification
|
GO:0030278 |
58 |
0.477
|
|
|
|
endothelial cell migration
|
GO:0043542 |
86 |
0.477
|
|
|
|
negative regulation of myoblast differentiation
|
GO:0045662 |
7 |
0.469
|
|
|
|
regulation of catagen
|
GO:0051794 |
3 |
0.466
|
|
|
|
mesodermal cell fate commitment
|
GO:0001710 |
2 |
0.466
|
|
|
|
determination of bilateral symmetry
|
GO:0009855 |
15 |
0.465
|
|
|
|
multicellular organismal macromolecule metabolic process
|
GO:0044259 |
29 |
0.463
|
|
|
|
regulation of cartilage development
|
GO:0061035 |
12 |
0.459
|
|
|
|
regulation of organ morphogenesis
|
GO:2000027 |
24 |
0.456
|
|
|
|
anatomical structure regression
|
GO:0060033 |
1 |
0.454
|
|
|
|
regulation of canonical wnt signaling pathway
|
GO:0060828 |
88 |
0.452
|
|
|
|
fibroblast migration
|
GO:0010761 |
7 |
0.448
|
|
|
|
inner ear development
|
GO:0048839 |
8 |
0.447
|
|
|
|
regulation of collagen biosynthetic process
|
GO:0032965 |
11 |
0.446
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.444
|
|
|
|
endodermal cell fate specification
|
GO:0001714 |
4 |
0.441
|
|
|
|
regulation of skeletal muscle fiber development
|
GO:0048742 |
12 |
0.438
|
|
|
|
hematopoietic progenitor cell differentiation
|
GO:0002244 |
38 |
0.433
|
Human |
|
|
regulation of determination of dorsal identity
|
GO:2000015 |
2 |
0.432
|
|
|
|
blood vessel endothelial cell proliferation involved in sprouting angiogenesis
|
GO:0002043 |
3 |
0.431
|
|
|
|
smad protein import into nucleus
|
GO:0007184 |
13 |
0.427
|
|
|
|
positive regulation of erythrocyte differentiation
|
GO:0045648 |
11 |
0.426
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
125 |
0.425
|
Human Zebrafish |
|
|
endocardial cushion cell fate commitment
|
GO:0061445 |
1 |
0.425
|
|
|
|
positive regulation of p38mapk cascade
|
GO:1900745 |
8 |
0.420
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.419
|
|
|
|
epithelial cell fate commitment
|
GO:0072148 |
3 |
0.419
|
|
|
|
endothelial cell proliferation
|
GO:0001935 |
65 |
0.419
|
|
|
|
muscle cell fate commitment
|
GO:0042693 |
4 |
0.416
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.415
|
|
|
|
mesonephric tubule morphogenesis
|
GO:0072171 |
10 |
0.412
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
136 |
0.410
|
Human |
|
|
chondrocyte differentiation
|
GO:0002062 |
17 |
0.406
|
|
|
|
lung morphogenesis
|
GO:0060425 |
6 |
0.405
|
|
|
|
response to host defenses
|
GO:0052200 |
2 |
0.405
|
|
|
|
response to growth factor
|
GO:0070848 |
205 |
0.403
|
|
|
|
regulation of cardiac muscle tissue development
|
GO:0055024 |
13 |
0.402
|
|
|
|
cellular response to transforming growth factor beta stimulus
|
GO:0071560 |
94 |
0.400
|
|
|
|
organ morphogenesis
|
GO:0009887 |
147 |
0.400
|
|
|
|
regulation of stem cell proliferation
|
GO:0072091 |
15 |
0.400
|
|
|
|
pulmonary artery morphogenesis
|
GO:0061156 |
3 |
0.399
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
177 |
0.395
|
|
|
|
connective tissue development
|
GO:0061448 |
39 |
0.395
|
|
|
|
dna replication
|
GO:0006260 |
116 |
0.393
|
|
|
|
positive regulation of cellular component movement
|
GO:0051272 |
181 |
0.392
|
|
|
|
negative regulation of stem cell proliferation
|
GO:2000647 |
3 |
0.392
|
|
|
|
heart field specification
|
GO:0003128 |
2 |
0.391
|
|
|
|
smoothened signaling pathway
|
GO:0007224 |
14 |
0.390
|
|
|
|
regulation of endodermal cell fate specification
|
GO:0042663 |
1 |
0.389
|
|
|
|
cardiac atrium development
|
GO:0003230 |
10 |
0.388
|
|
|
|
regulation of aldosterone metabolic process
|
GO:0032344 |
6 |
0.387
|
|
|
|
regulation of osteoblast differentiation
|
GO:0045667 |
38 |
0.387
|
|
|
|
embryonic heart tube morphogenesis
|
GO:0003143 |
8 |
0.385
|
|
|
|
nephron development
|
GO:0072006 |
30 |
0.383
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.381
|
|
|
|
heart induction
|
GO:0003129 |
4 |
0.380
|
|
|
|
mineralocorticoid biosynthetic process
|
GO:0006705 |
9 |
0.379
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
172 |
0.377
|
|
|
|
gastrulation
|
GO:0007369 |
51 |
0.376
|
|
|
|
chondrocyte differentiation involved in endochondral bone morphogenesis
|
GO:0003413 |
1 |
0.372
|
|
|
|
mesodermal cell fate specification
|
GO:0007501 |
2 |
0.372
|
|
|
|
pericardium development
|
GO:0060039 |
2 |
0.371
|
|
|
|
collagen biosynthetic process
|
GO:0032964 |
15 |
0.370
|
|
|
|
cardiovascular system development
|
GO:0072358 |
262 |
0.369
|
|
|
|
muscle tissue morphogenesis
|
GO:0060415 |
19 |
0.363
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.363
|
|
|
|
circulatory system development
|
GO:0072359 |
262 |
0.360
|
|
|
|
thymocyte apoptotic process
|
GO:0070242 |
2 |
0.359
|
|
|
|
regulation of striated muscle cell differentiation
|
GO:0051153 |
25 |
0.359
|
|
|
|
regulation of cell cell adhesion
|
GO:0022407 |
57 |
0.356
|
Human |
|
|
negative regulation of calcium ion transport into cytosol
|
GO:0010523 |
3 |
0.355
|
|
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
61 |
0.353
|
Human |
|
|
heart valve morphogenesis
|
GO:0003179 |
8 |
0.351
|
|
|
|
positive regulation of stress activated protein kinase signaling cascade
|
GO:0070304 |
61 |
0.348
|
|
|
|
cartilage development
|
GO:0051216 |
31 |
0.347
|
|
|
|
positive regulation of hair follicle development
|
GO:0051798 |
3 |
0.346
|
Human |
|
|
regulation of protein secretion
|
GO:0050708 |
86 |
0.344
|
|
|
|
positive regulation of stress activated mapk cascade
|
GO:0032874 |
60 |
0.340
|
|
|
|
canonical wnt signaling pathway
|
GO:0060070 |
116 |
0.339
|
|
|
|
cardiac atrium morphogenesis
|
GO:0003209 |
7 |
0.338
|
|
|
|
negative regulation of leukocyte differentiation
|
GO:1902106 |
24 |
0.336
|
Human |
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
181 |
0.334
|
|
|
|
septum primum development
|
GO:0003284 |
1 |
0.333
|
|
|
|
regulation of wnt signaling pathway involved in heart development
|
GO:0003307 |
3 |
0.332
|
|
|
|
aldosterone biosynthetic process
|
GO:0032342 |
9 |
0.329
|
|
|
|
cellular response to biotic stimulus
|
GO:0071216 |
71 |
0.329
|
|
|
|
regulation of chorionic trophoblast cell proliferation
|
GO:1901382 |
2 |
0.328
|
|
|
|
hair cycle
|
GO:0042633 |
28 |
0.327
|
Human |
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.325
|
|
|
|
lens development in camera type eye
|
GO:0002088 |
2 |
0.325
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.324
|
Human |
|
|
nephron tubule development
|
GO:0072080 |
17 |
0.322
|
|
|
|
anatomical structure maturation
|
GO:0071695 |
9 |
0.321
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
166 |
0.321
|
Human |
|
|
positive regulation of immunoglobulin mediated immune response
|
GO:0002891 |
4 |
0.315
|
|
|
|
positive regulation of muscle cell differentiation
|
GO:0051149 |
15 |
0.314
|
|
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.313
|
|
|
|
negative regulation of wnt signaling pathway
|
GO:0030178 |
69 |
0.309
|
|
|
|
regulation of lung blood pressure
|
GO:0014916 |
1 |
0.305
|
|
|
|
negative regulation of epithelial cell proliferation
|
GO:0050680 |
48 |
0.304
|
|
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.302
|
|
|
|
cellular response to external stimulus
|
GO:0071496 |
111 |
0.301
|
|
|
|
negative regulation of transcription from rna polymerase ii promoter
|
GO:0000122 |
281 |
0.299
|
Human |
|
|
cellular response to steroid hormone stimulus
|
GO:0071383 |
37 |
0.296
|
|
|
|
endothelial cell fate commitment
|
GO:0060839 |
3 |
0.294
|
|
|
|
negative regulation of embryonic development
|
GO:0045992 |
4 |
0.294
|
|
|
|
regulation of interleukin 17 production
|
GO:0032660 |
12 |
0.291
|
|
|
|
regulation of muscle cell differentiation
|
GO:0051147 |
31 |
0.290
|
|
|
|
sprouting angiogenesis
|
GO:0002040 |
29 |
0.289
|
|
|
|
protein secretion
|
GO:0009306 |
98 |
0.289
|
|
|
|
negative regulation of cell fate commitment
|
GO:0010454 |
3 |
0.283
|
|
|
|
branching morphogenesis of an epithelial tube
|
GO:0048754 |
19 |
0.281
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.280
|
Human |
|
|
ureteric bud development
|
GO:0001657 |
13 |
0.278
|
|
|
|
embryonic organ development
|
GO:0048568 |
36 |
0.277
|
Zebrafish |
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.275
|
|
|
|
hemopoiesis
|
GO:0030097 |
180 |
0.274
|
Human |
|
|
mitral valve morphogenesis
|
GO:0003183 |
2 |
0.272
|
|
|
|
regulation of vasculature development
|
GO:1901342 |
97 |
0.272
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.270
|
|
|
|
epithelial tube branching involved in lung morphogenesis
|
GO:0060441 |
4 |
0.270
|
|
|
|
cardiac endothelial cell differentiation
|
GO:0003348 |
2 |
0.269
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.266
|
|
|
|
skeletal muscle fiber development
|
GO:0048741 |
12 |
0.264
|
|
|
|
branching involved in ureteric bud morphogenesis
|
GO:0001658 |
9 |
0.262
|
|
|
|
dorsal ventral pattern formation
|
GO:0009953 |
15 |
0.261
|
Zebrafish |
|
|
osteoblast differentiation
|
GO:0001649 |
92 |
0.261
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.260
|
|
|
|
striated muscle cell differentiation
|
GO:0051146 |
43 |
0.260
|
|
|
|
cardiac muscle cell differentiation
|
GO:0055007 |
15 |
0.259
|
|
|
|
transforming growth factor beta receptor signaling pathway
|
GO:0007179 |
76 |
0.256
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
156 |
0.255
|
|
|
|
negative regulation of epithelial cell migration
|
GO:0010633 |
38 |
0.254
|
|
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.254
|
|
|
|
regulation of epidermis development
|
GO:0045682 |
19 |
0.254
|
Human |
|
|
blood circulation
|
GO:0008015 |
113 |
0.254
|
|
|
|
negative regulation of cell fate specification
|
GO:0009996 |
3 |
0.254
|
|
|
|
positive regulation of blood vessel endothelial cell migration
|
GO:0043536 |
16 |
0.253
|
|
|
|
regulation of leukocyte activation
|
GO:0002694 |
115 |
0.253
|
|
|
|
negative regulation of t cell apoptotic process
|
GO:0070233 |
4 |
0.253
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
119 |
0.249
|
|
|
|
semicircular canal morphogenesis
|
GO:0048752 |
1 |
0.249
|
|
|
|
t cell activation
|
GO:0042110 |
99 |
0.249
|
|
|
|
response to electrical stimulus
|
GO:0051602 |
1 |
0.248
|
|
|
|
regulation of neuroblast proliferation
|
GO:1902692 |
3 |
0.247
|
|
|
|
kidney epithelium development
|
GO:0072073 |
25 |
0.246
|
|
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.243
|
|
|
|
positive regulation of b cell mediated immunity
|
GO:0002714 |
4 |
0.242
|
|
|
|
response to transforming growth factor beta
|
GO:0071559 |
94 |
0.241
|
|
|
|
regulation of myotube differentiation
|
GO:0010830 |
18 |
0.240
|
|
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.240
|
|
|
|
regulation of transforming growth factor beta receptor signaling pathway
|
GO:0017015 |
48 |
0.238
|
|
|
|
bmp signaling pathway
|
GO:0030509 |
49 |
0.236
|
Human Zebrafish |
|
|
response to bmp
|
GO:0071772 |
8 |
0.233
|
|
|
|
regulation of smooth muscle cell proliferation
|
GO:0048660 |
28 |
0.232
|
|
|
|
cardiocyte differentiation
|
GO:0035051 |
23 |
0.231
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
128 |
0.229
|
|
|
|
response to other organism
|
GO:0051707 |
261 |
0.229
|
|
|
|
embryonic morphogenesis
|
GO:0048598 |
85 |
0.228
|
|
|
|
positive regulation of wnt signaling pathway
|
GO:0030177 |
54 |
0.228
|
|
|
|
endodermal cell fate commitment
|
GO:0001711 |
4 |
0.228
|
|
|
|
regulation of cell morphogenesis involved in differentiation
|
GO:0010769 |
83 |
0.226
|
|
|
|
negative regulation of epidermal cell differentiation
|
GO:0045605 |
4 |
0.222
|
|
|
|
response to sterol
|
GO:0036314 |
14 |
0.221
|
|
|
|
positive regulation of cell adhesion
|
GO:0045785 |
84 |
0.221
|
Human |
|
|
blood vessel morphogenesis
|
GO:0048514 |
162 |
0.220
|
|
|
|
negative regulation of glucocorticoid metabolic process
|
GO:0031944 |
4 |
0.220
|
|
|
|
enteroendocrine cell differentiation
|
GO:0035883 |
6 |
0.220
|
|
|
|
regulation of t cell activation
|
GO:0050863 |
77 |
0.219
|
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.219
|
|
|
|
cartilage development involved in endochondral bone morphogenesis
|
GO:0060351 |
2 |
0.219
|
|
|
|
ketone biosynthetic process
|
GO:0042181 |
17 |
0.218
|
|
|
|
epithelial cell migration
|
GO:0010631 |
119 |
0.214
|
|
|
|
protein import
|
GO:0017038 |
130 |
0.214
|
|
|
|
regulation of skeletal muscle tissue development
|
GO:0048641 |
15 |
0.211
|
|
|
|
regulation of endothelial cell proliferation
|
GO:0001936 |
56 |
0.210
|
|
|
|
metanephric s shaped body morphogenesis
|
GO:0072284 |
4 |
0.210
|
|
|
|
response to alcohol
|
GO:0097305 |
64 |
0.208
|
|
|
|
organ induction
|
GO:0001759 |
4 |
0.208
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
204 |
0.207
|
|
|
|
embryonic organ morphogenesis
|
GO:0048562 |
24 |
0.207
|
|
|
|
cellular response to glucocorticoid stimulus
|
GO:0071385 |
4 |
0.207
|
|
|
|
regulation of cell activation
|
GO:0050865 |
125 |
0.206
|
|
|
|
regulation of t cell proliferation
|
GO:0042129 |
42 |
0.203
|
|
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.202
|
|
|
|
lymphatic endothelial cell differentiation
|
GO:0060836 |
3 |
0.201
|
|
|
|
positive regulation of mesenchymal cell proliferation
|
GO:0002053 |
2 |
0.199
|
|
|
|
nephron epithelium development
|
GO:0072009 |
23 |
0.199
|
|
|
|
regulation of heart morphogenesis
|
GO:2000826 |
4 |
0.199
|
|
|
|
glycoprotein metabolic process
|
GO:0009100 |
110 |
0.198
|
|
|
|
ossification
|
GO:0001503 |
121 |
0.196
|
|
|
|
regulation of protein targeting
|
GO:1903533 |
91 |
0.195
|
|
|
|
mammary gland morphogenesis
|
GO:0060443 |
2 |
0.194
|
|
|
|
negative regulation of leukocyte activation
|
GO:0002695 |
26 |
0.193
|
|
|
|
cellular response to corticosteroid stimulus
|
GO:0071384 |
5 |
0.193
|
|
|
|
endochondral bone morphogenesis
|
GO:0060350 |
3 |
0.192
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.192
|
|
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.191
|
|
|
|
positive regulation of homeostatic process
|
GO:0032846 |
47 |
0.191
|
|
|
|
mesonephric tubule development
|
GO:0072164 |
14 |
0.190
|
|
|
|
striated muscle tissue development
|
GO:0014706 |
59 |
0.189
|
|
|
|
sequestering of metal ion
|
GO:0051238 |
24 |
0.187
|
|
|
|
regulation of stress activated protein kinase signaling cascade
|
GO:0070302 |
85 |
0.187
|
|
|
|
negative regulation of cortisol biosynthetic process
|
GO:2000065 |
4 |
0.187
|
|
|
|
negative regulation of systemic arterial blood pressure
|
GO:0003085 |
1 |
0.187
|
|
|
|
response to lipoteichoic acid
|
GO:0070391 |
3 |
0.186
|
|
|
|
macrophage cytokine production
|
GO:0010934 |
4 |
0.185
|
|
|
|
positive regulation of fibroblast migration
|
GO:0010763 |
3 |
0.183
|
|
|
|
regulation of ketone biosynthetic process
|
GO:0010566 |
7 |
0.182
|
|
|
|
ear development
|
GO:0043583 |
14 |
0.181
|
|
|
|
transforming growth factor beta production
|
GO:0071604 |
14 |
0.180
|
|
|
|
regulation of hormone levels
|
GO:0010817 |
125 |
0.178
|
|
|
|
neuroblast proliferation
|
GO:0007405 |
4 |
0.176
|
|
|
|
single organismal cell cell adhesion
|
GO:0016337 |
148 |
0.175
|
Human |
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.175
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.175
|
|
|
|
positive regulation of epithelial cell proliferation
|
GO:0050679 |
65 |
0.174
|
|
|
|
cell proliferation involved in kidney development
|
GO:0072111 |
3 |
0.174
|
|
|
|
embryonic skeletal system development
|
GO:0048706 |
13 |
0.174
|
|
|
|
response to mechanical stimulus
|
GO:0009612 |
51 |
0.173
|
|
|
|
immune system development
|
GO:0002520 |
195 |
0.173
|
Human |
|
|
regulation of organ formation
|
GO:0003156 |
4 |
0.172
|
|
|
|
regulation of fibroblast migration
|
GO:0010762 |
7 |
0.171
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
113 |
0.171
|
|
|
|
embryonic skeletal joint morphogenesis
|
GO:0060272 |
2 |
0.170
|
|
|
|
response to lipid
|
GO:0033993 |
206 |
0.170
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.169
|
|
|
|
regulation of mononuclear cell proliferation
|
GO:0032944 |
65 |
0.169
|
|
|
|
cytokine production
|
GO:0001816 |
247 |
0.168
|
|
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
136 |
0.168
|
|
|
|
ear morphogenesis
|
GO:0042471 |
7 |
0.168
|
|
|
|
regulation of cortisol biosynthetic process
|
GO:2000064 |
5 |
0.167
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
108 |
0.167
|
|
|
|
positive regulation of interleukin 17 production
|
GO:0032740 |
8 |
0.167
|
|
|
|
regulation of lymphocyte proliferation
|
GO:0050670 |
64 |
0.167
|
|
|
|
negative regulation of canonical wnt signaling pathway
|
GO:0090090 |
55 |
0.167
|
|
|
|
skin development
|
GO:0043588 |
76 |
0.166
|
Human |
|
|
regulation of cell morphogenesis
|
GO:0022604 |
153 |
0.165
|
|
|
|
epithelial tube morphogenesis
|
GO:0060562 |
38 |
0.164
|
|
|
|
oogenesis
|
GO:0048477 |
2 |
0.164
|
|
|
|
positive regulation of dna metabolic process
|
GO:0051054 |
73 |
0.162
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.162
|
|
|
|
brain development
|
GO:0007420 |
97 |
0.161
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.161
|
|
|
|
myeloid dendritic cell activation
|
GO:0001773 |
4 |
0.160
|
|
|
|
glial cell migration
|
GO:0008347 |
4 |
0.160
|
|
|
|
epithelium development
|
GO:0060429 |
227 |
0.160
|
Human |
|
|
specification of symmetry
|
GO:0009799 |
16 |
0.160
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.160
|
|
|
|
regulation of alkaline phosphatase activity
|
GO:0010692 |
2 |
0.159
|
|
|
|
heart development
|
GO:0007507 |
95 |
0.157
|
|
|
|
response to host
|
GO:0075136 |
2 |
0.157
|
|
|
|
chordate embryonic development
|
GO:0043009 |
34 |
0.155
|
|
|
|
cardiac chamber development
|
GO:0003205 |
30 |
0.155
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
232 |
0.152
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.151
|
|
|
|
regulation of protein import into nucleus
|
GO:0042306 |
78 |
0.151
|
|
|
|
regulation of binding
|
GO:0051098 |
111 |
0.148
|
|
|
|
negative regulation of wnt signaling pathway involved in heart development
|
GO:0003308 |
2 |
0.148
|
|
|
|
collagen fibril organization
|
GO:0030199 |
10 |
0.148
|
|
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
70 |
0.147
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
75 |
0.147
|
|
|
|
regulation of cardiac muscle cell proliferation
|
GO:0060043 |
4 |
0.147
|
|
|
|
collagen metabolic process
|
GO:0032963 |
28 |
0.147
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
180 |
0.147
|
|
|
|
blood vessel development
|
GO:0001568 |
172 |
0.146
|
|
|
|
segmentation
|
GO:0035282 |
4 |
0.145
|
|
|
|
regulation of mitosis
|
GO:0007088 |
63 |
0.145
|
|
|
|
positive regulation of secretion by cell
|
GO:1903532 |
108 |
0.145
|
|
|
|
response to bacterium
|
GO:0009617 |
144 |
0.145
|
|
|
|
defense response
|
GO:0006952 |
315 |
0.144
|
|
|
|
negative regulation of release of sequestered calcium ion into cytosol
|
GO:0051280 |
1 |
0.142
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.142
|
|
|
|
angiogenesis
|
GO:0001525 |
147 |
0.142
|
|
|
|
embryonic skeletal joint development
|
GO:0072498 |
2 |
0.141
|
|
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
99 |
0.141
|
|
|
|
metanephric nephron morphogenesis
|
GO:0072273 |
7 |
0.141
|
|
|
|
internal peptidyl lysine acetylation
|
GO:0018393 |
97 |
0.141
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
103 |
0.141
|
|
|
|
regulation of neural precursor cell proliferation
|
GO:2000177 |
4 |
0.140
|
|
|
|
negative regulation of metanephros development
|
GO:0072217 |
1 |
0.140
|
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
167 |
0.139
|
|
|
|
negative regulation of leukocyte proliferation
|
GO:0070664 |
16 |
0.139
|
|
|
|
regulation of bmp signaling pathway
|
GO:0030510 |
27 |
0.139
|
Human Zebrafish |
|
|
t cell proliferation
|
GO:0042098 |
45 |
0.138
|
|
|
|
nuclear transport
|
GO:0051169 |
179 |
0.138
|
|
|
|
cardiac chamber morphogenesis
|
GO:0003206 |
26 |
0.138
|
|
|
|
cardiac muscle fiber development
|
GO:0048739 |
4 |
0.136
|
|
|
|
digestive system development
|
GO:0055123 |
75 |
0.136
|
|
|
|
type b pancreatic cell development
|
GO:0003323 |
4 |
0.135
|
|
|
|
positive regulation of endothelial cell proliferation
|
GO:0001938 |
37 |
0.134
|
|
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
127 |
0.134
|
|
|
|
sensory organ development
|
GO:0007423 |
52 |
0.134
|
|
|
|
epithelium migration
|
GO:0090132 |
119 |
0.134
|
|
|
|
positive regulation of protein import into nucleus
|
GO:0042307 |
46 |
0.133
|
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
125 |
0.133
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.132
|
|
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
84 |
0.132
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
179 |
0.132
|
Human |
|
|
protein dephosphorylation
|
GO:0006470 |
81 |
0.131
|
|
|
|
defense response to fungus
|
GO:0050832 |
4 |
0.131
|
|
|
|
astrocyte differentiation
|
GO:0048708 |
4 |
0.129
|
|
|
|
extracellular matrix organization
|
GO:0030198 |
41 |
0.128
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
104 |
0.127
|
|
|
|
t cell differentiation in thymus
|
GO:0033077 |
4 |
0.127
|
|
|
|
cell proliferation involved in heart morphogenesis
|
GO:0061323 |
1 |
0.126
|
|
|
|
negative regulation of cell cell adhesion
|
GO:0022408 |
27 |
0.126
|
|
|
|
negative regulation of aldosterone biosynthetic process
|
GO:0032348 |
4 |
0.126
|
|
|
|
regulation of cardiac muscle cell differentiation
|
GO:2000725 |
7 |
0.126
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
135 |
0.125
|
|
|
|
myeloid dendritic cell differentiation
|
GO:0043011 |
3 |
0.125
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
63 |
0.125
|
|
|
|
stem cell differentiation
|
GO:0048863 |
93 |
0.124
|
|
|
|
positive regulation of behavior
|
GO:0048520 |
60 |
0.123
|
|
|
|
purine nucleotide biosynthetic process
|
GO:0006164 |
84 |
0.123
|
|
|
|
positive regulation of intracellular transport
|
GO:0032388 |
104 |
0.123
|
|
|
|
mesodermal cell differentiation
|
GO:0048333 |
10 |
0.123
|
|
|
|
embryonic skeletal system morphogenesis
|
GO:0048704 |
9 |
0.122
|
|
|
|
positive regulation of protein secretion
|
GO:0050714 |
60 |
0.122
|
|
|
|
negative regulation of insulin like growth factor receptor signaling pathway
|
GO:0043569 |
4 |
0.121
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.121
|
|
|
|
regulation of phosphatase activity
|
GO:0010921 |
81 |
0.121
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.121
|
|
|
|
chemical homeostasis
|
GO:0048878 |
306 |
0.120
|
|
|
|
dephosphorylation
|
GO:0016311 |
209 |
0.120
|
|
|
|
cation homeostasis
|
GO:0055080 |
189 |
0.120
|
|
|
|
regulation of secretion
|
GO:0051046 |
194 |
0.120
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
0.119
|
|
|
|
positive regulation of reactive oxygen species metabolic process
|
GO:2000379 |
24 |
0.119
|
|
|
|
positive regulation of protein localization to nucleus
|
GO:1900182 |
48 |
0.119
|
|
|
|
epidermis morphogenesis
|
GO:0048730 |
3 |
0.117
|
|
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.117
|
|
