IMP
Process View
collagen biosynthetic process
The chemical reactions and pathways resulting in the formation of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals. Collagen is highly enriched in glycine (some regions are 33% glycine) and proline, occurring predominantly as 3-hydroxyproline (about 20%).
Loading network...
In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "collagen biosynthetic process"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| PDGFRA | platelet-derived growth factor receptor, alpha polypeptide | 0.716 | ||
| COL1A2 | collagen, type I, alpha 2 | 0.644 | Human | |
| COL4A1 | collagen, type IV, alpha 1 | 0.595 | ||
| FSTL1 | follistatin-like 1 | 0.370 | ||
| COL4A2 | collagen, type IV, alpha 2 | 0.301 | ||
| BMPR1A | bone morphogenetic protein receptor, type IA | 0.253 | ||
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 0.226 | ||
| DDR2 | discoidin domain receptor tyrosine kinase 2 | 0.222 | ||
| PDGFB | platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog) | 0.128 | ||
| COL1A1 | collagen, type I, alpha 1 | 0.121 | ||
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | 0.099 | ||
| ENG | endoglin | 0.094 | ||
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.093 | ||
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.084 | ||
| COL6A1 | collagen, type VI, alpha 1 | 0.077 | ||
| PKD1 | polycystic kidney disease 1 (autosomal dominant) | 0.066 | ||
| PXDN | peroxidasin homolog (Drosophila) | 0.062 | ||
| FN1 | fibronectin 1 | 0.054 | ||
| MXRA5 | matrix-remodelling associated 5 | 0.053 | ||
| LOX | lysyl oxidase | 0.048 | ||
| THBS1 | thrombospondin 1 | 0.042 | ||
| COL3A1 | collagen, type III, alpha 1 | 0.041 | Human | |
| CYR61 | cysteine-rich, angiogenic inducer, 61 | 0.041 | ||
| POSTN | periostin, osteoblast specific factor | 0.036 | ||
| ALB | albumin | 0.028 | ||
| BGN | biglycan | 0.028 | ||
| LTBP2 | latent transforming growth factor beta binding protein 2 | 0.028 | ||
| TGFB3 | transforming growth factor, beta 3 | 0.028 | ||
| COL6A2 | collagen, type VI, alpha 2 | 0.027 | ||
| MMP2 | matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase) | 0.026 | ||
| TMBIM6 | transmembrane BAX inhibitor motif containing 6 | 0.026 | ||
| ELN | elastin | 0.024 | ||
| PPARGC1A | peroxisome proliferator-activated receptor gamma, coactivator 1 alpha | 0.022 | ||
| CAV1 | caveolin 1, caveolae protein, 22kDa | 0.022 | ||
| TECPR1 | tectonin beta-propeller repeat containing 1 | 0.020 | ||
| CANX | calnexin | 0.019 | ||
| S100B | S100 calcium binding protein B | 0.019 | ||
| ADAM12 | ADAM metallopeptidase domain 12 | 0.018 | ||
| IL6R | interleukin 6 receptor | 0.018 | ||
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.018 | ||
| MMP11 | matrix metallopeptidase 11 (stromelysin 3) | 0.017 | ||
| COL5A2 | collagen, type V, alpha 2 | 0.017 | Human | |
| DAB2 | disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila) | 0.017 | ||
| PCOLCE | procollagen C-endopeptidase enhancer | 0.016 | ||
| THY1 | Thy-1 cell surface antigen | 0.014 | ||
| CAV2 | caveolin 2 | 0.014 | ||
| IL6 | interleukin 6 (interferon, beta 2) | 0.014 | ||
| NRP1 | neuropilin 1 | 0.014 | ||
| LAMB1 | laminin, beta 1 | 0.013 | ||
| HSPG2 | heparan sulfate proteoglycan 2 | 0.013 | ||
| CD248 | CD248 molecule, endosialin | 0.013 | ||
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.013 | ||
| WISP1 | WNT1 inducible signaling pathway protein 1 | 0.012 | ||
| MFAP2 | microfibrillar-associated protein 2 | 0.012 | ||
| FGF18 | fibroblast growth factor 18 | 0.012 | ||
| COL6A3 | collagen, type VI, alpha 3 | 0.012 | ||
| SULF1 | sulfatase 1 | 0.011 | ||
| F3 | coagulation factor III (thromboplastin, tissue factor) | 0.011 | ||
| PLXDC1 | plexin domain containing 1 | 0.011 | ||
| TMED10 | transmembrane emp24-like trafficking protein 10 (yeast) | 0.011 | ||
| FBN1 | fibrillin 1 | 0.010 | ||
| NID2 | nidogen 2 (osteonidogen) | 0.010 |