|
|
positive regulation of arp2 3 complex mediated actin nucleation
|
GO:2000601 |
5 |
1.000
|
Human |
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.999
|
Human |
|
|
regulation of actin filament polymerization
|
GO:0030833 |
50 |
0.997
|
Human |
|
|
regulation of actin nucleation
|
GO:0051125 |
10 |
0.994
|
Human |
|
|
regulation of arp2 3 complex mediated actin nucleation
|
GO:0034315 |
6 |
0.992
|
Human |
|
|
regulation of protein complex assembly
|
GO:0043254 |
147 |
0.991
|
Human |
|
|
regulation of actin filament based process
|
GO:0032970 |
141 |
0.990
|
Human |
|
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
116 |
0.989
|
Human |
|
|
rap protein signal transduction
|
GO:0032486 |
7 |
0.989
|
|
|
|
regulation of actin polymerization or depolymerization
|
GO:0008064 |
56 |
0.988
|
Human |
|
|
rho protein signal transduction
|
GO:0007266 |
26 |
0.986
|
|
|
|
regulation of protein polymerization
|
GO:0032271 |
63 |
0.986
|
Human |
|
|
actin filament polymerization
|
GO:0030041 |
45 |
0.981
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
177 |
0.976
|
Human |
|
|
regulation of cellular component size
|
GO:0032535 |
82 |
0.972
|
Human |
|
|
actin filament organization
|
GO:0007015 |
128 |
0.971
|
Human |
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.970
|
Human |
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
244 |
0.970
|
|
|
|
cellular protein complex assembly
|
GO:0043623 |
188 |
0.966
|
|
|
|
positive regulation of protein complex assembly
|
GO:0031334 |
86 |
0.960
|
Human |
|
|
regulation of anatomical structure size
|
GO:0090066 |
101 |
0.957
|
Human |
|
|
positive regulation of actin filament polymerization
|
GO:0030838 |
38 |
0.950
|
Human |
|
|
positive regulation of protein polymerization
|
GO:0032273 |
45 |
0.947
|
Human |
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
324 |
0.940
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.926
|
Human |
|
|
positive regulation of rac gtpase activity
|
GO:0032855 |
31 |
0.917
|
|
|
|
gtp metabolic process
|
GO:0046039 |
239 |
0.913
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
404 |
0.911
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
391 |
0.910
|
|
|
|
gtp catabolic process
|
GO:0006184 |
237 |
0.895
|
|
|
|
regulation of actin filament length
|
GO:0030832 |
56 |
0.893
|
Human |
|
|
actin cytoskeleton organization
|
GO:0030036 |
207 |
0.885
|
Human Fly |
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.882
|
Human Worm |
|
|
actin filament based process
|
GO:0030029 |
224 |
0.866
|
Human Fly |
|
|
positive regulation of rap gtpase activity
|
GO:0032854 |
8 |
0.864
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
405 |
0.857
|
|
|
|
endosomal transport
|
GO:0016197 |
129 |
0.857
|
|
|
|
rac protein signal transduction
|
GO:0016601 |
12 |
0.854
|
Human |
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.853
|
Mouse Fly |
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
412 |
0.853
|
|
|
|
cell activation
|
GO:0001775 |
213 |
0.848
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.842
|
|
|
|
positive regulation of immune system process
|
GO:0002684 |
283 |
0.838
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.834
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
398 |
0.832
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.831
|
|
|
|
regulation of small gtpase mediated signal transduction
|
GO:0051056 |
156 |
0.828
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.822
|
Mouse Fly |
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
239 |
0.819
|
|
|
|
positive regulation of ras gtpase activity
|
GO:0032320 |
117 |
0.815
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.805
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
394 |
0.797
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.787
|
Mouse Fly |
|
|
mononuclear cell proliferation
|
GO:0032943 |
71 |
0.785
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
408 |
0.784
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.784
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
411 |
0.780
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.779
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
205 |
0.777
|
|
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
186 |
0.775
|
|
|
|
positive regulation of rho gtpase activity
|
GO:0032321 |
56 |
0.774
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
405 |
0.763
|
|
|
|
lymphocyte proliferation
|
GO:0046651 |
70 |
0.761
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.756
|
|
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
4 |
0.742
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.741
|
|
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
166 |
0.728
|
|
|
|
regulation of rap protein signal transduction
|
GO:0032487 |
9 |
0.722
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.708
|
|
|
|
cell projection organization
|
GO:0030030 |
252 |
0.701
|
Mouse Worm Fly |
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.701
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.684
|
Mouse Fly |
|
|
protein polymerization
|
GO:0051258 |
71 |
0.678
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.666
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
209 |
0.655
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
0.652
|
|
|
|
positive regulation of map kinase activity
|
GO:0043406 |
80 |
0.641
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.626
|
|
|
|
arp2 3 complex mediated actin nucleation
|
GO:0034314 |
17 |
0.605
|
Human |
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
84 |
0.604
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
205 |
0.601
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
227 |
0.588
|
|
|
|
regulation of pro b cell differentiation
|
GO:2000973 |
1 |
0.576
|
|
|
|
phospholipid metabolic process
|
GO:0006644 |
99 |
0.575
|
|
|
|
positive regulation of gtpase activity
|
GO:0043547 |
166 |
0.573
|
|
|
|
neuron projection development
|
GO:0031175 |
106 |
0.568
|
Fly |
|
|
leukocyte activation
|
GO:0045321 |
164 |
0.563
|
|
|
|
cellular response to fibroblast growth factor stimulus
|
GO:0044344 |
39 |
0.559
|
|
|
|
actin polymerization or depolymerization
|
GO:0008154 |
56 |
0.557
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
155 |
0.557
|
|
|
|
positive regulation of cytoskeleton organization
|
GO:0051495 |
83 |
0.552
|
Human |
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
269 |
0.551
|
|
|
|
regulation of jnk cascade
|
GO:0046328 |
73 |
0.540
|
|
|
|
regulation of mononuclear cell proliferation
|
GO:0032944 |
65 |
0.540
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
264 |
0.540
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
392 |
0.533
|
|
|
|
regulation of rho protein signal transduction
|
GO:0035023 |
79 |
0.529
|
|
|
|
antigen receptor mediated signaling pathway
|
GO:0050851 |
38 |
0.511
|
|
|
|
wound healing
|
GO:0042060 |
115 |
0.500
|
|
|
|
exocytosis
|
GO:0006887 |
71 |
0.485
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
408 |
0.481
|
|
|
|
regulation of hormone levels
|
GO:0010817 |
125 |
0.479
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
195 |
0.470
|
Human |
|
|
regulation of ras gtpase activity
|
GO:0032318 |
128 |
0.460
|
|
|
|
regulation of cell activation
|
GO:0050865 |
125 |
0.458
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.454
|
|
|
|
regulation of cell morphogenesis
|
GO:0022604 |
153 |
0.453
|
Fly |
|
|
cell adhesion
|
GO:0007155 |
325 |
0.448
|
Fly |
|
|
regulation of rho gtpase activity
|
GO:0032319 |
66 |
0.444
|
|
|
|
mapk cascade
|
GO:0000165 |
288 |
0.442
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.433
|
Worm Fly |
|
|
leukocyte proliferation
|
GO:0070661 |
74 |
0.426
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.421
|
Mouse Fly |
|
|
regulation of leukocyte activation
|
GO:0002694 |
115 |
0.410
|
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
180 |
0.398
|
|
|
|
epithelium development
|
GO:0060429 |
227 |
0.389
|
Mouse |
|
|
regulation of t cell proliferation
|
GO:0042129 |
42 |
0.365
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
103 |
0.361
|
|
|
|
positive regulation of leukocyte activation
|
GO:0002696 |
80 |
0.357
|
|
|
|
lipid biosynthetic process
|
GO:0008610 |
177 |
0.353
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.347
|
Mouse Fly |
|
|
peptidyl serine phosphorylation
|
GO:0018105 |
101 |
0.345
|
|
|
|
regulation of gtpase activity
|
GO:0043087 |
180 |
0.342
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.341
|
Mouse Worm Fly |
|
|
cell projection assembly
|
GO:0030031 |
126 |
0.328
|
Fly |
|
|
regulation of leukocyte proliferation
|
GO:0070663 |
67 |
0.326
|
|
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.325
|
Mouse |
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
181 |
0.318
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.317
|
|
|
|
establishment or maintenance of bipolar cell polarity
|
GO:0061245 |
2 |
0.314
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.313
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
189 |
0.313
|
|
|
|
secretion
|
GO:0046903 |
254 |
0.311
|
|
|
|
regulation of exocytosis
|
GO:0017157 |
46 |
0.311
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.302
|
|
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
185 |
0.300
|
|
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.299
|
Worm |
|
|
endothelial cell development
|
GO:0001885 |
18 |
0.291
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.283
|
|
|
|
regulation of cell projection assembly
|
GO:0060491 |
47 |
0.282
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.281
|
|
|
|
negative regulation of actin filament polymerization
|
GO:0030837 |
10 |
0.280
|
|
|
|
regulation of immune response
|
GO:0050776 |
201 |
0.277
|
|
|
|
response to fibroblast growth factor
|
GO:0071774 |
39 |
0.269
|
|
|
|
positive regulation of secretion by cell
|
GO:1903532 |
108 |
0.267
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.266
|
|
|
|
lymphocyte activation
|
GO:0046649 |
133 |
0.266
|
|
|
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
185 |
0.262
|
|
|
|
regulation of lymphocyte proliferation
|
GO:0050670 |
64 |
0.259
|
|
|
|
jnk cascade
|
GO:0007254 |
80 |
0.255
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
158 |
0.255
|
Human |
|
|
cellular response to nerve growth factor stimulus
|
GO:1990090 |
6 |
0.253
|
|
|
|
leukocyte migration
|
GO:0050900 |
107 |
0.253
|
|
|
|
actin filament bundle assembly
|
GO:0051017 |
54 |
0.250
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.241
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.233
|
|
|
|
positive regulation of stress activated mapk cascade
|
GO:0032874 |
60 |
0.232
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.231
|
|
|
|
chemotaxis
|
GO:0006935 |
157 |
0.227
|
Fly |
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.226
|
Mouse Fly |
|
|
regulation of cell projection organization
|
GO:0031344 |
107 |
0.222
|
|
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.216
|
Mouse |
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
230 |
0.214
|
|
|
|
positive regulation of cell cycle
|
GO:0045787 |
140 |
0.210
|
|
|
|
lipid metabolic process
|
GO:0006629 |
381 |
0.205
|
|
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.203
|
Fly |
|
|
neural tube closure
|
GO:0001843 |
3 |
0.202
|
|
|
|
response to insulin
|
GO:0032868 |
45 |
0.200
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.198
|
|
|
|
engulfment of apoptotic cell
|
GO:0043652 |
2 |
0.197
|
Worm |
|
|
regulation of stress activated protein kinase signaling cascade
|
GO:0070302 |
85 |
0.189
|
|
|
|
barbed end actin filament capping
|
GO:0051016 |
3 |
0.187
|
|
|
|
positive regulation of cell projection organization
|
GO:0031346 |
64 |
0.179
|
|
|
|
circulatory system development
|
GO:0072359 |
262 |
0.178
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.168
|
|
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
99 |
0.166
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.163
|
|
|
|
cellular response to insulin stimulus
|
GO:0032869 |
41 |
0.161
|
|
|
|
primary neural tube formation
|
GO:0014020 |
3 |
0.161
|
|
|
|
regulation of t cell activation
|
GO:0050863 |
77 |
0.159
|
|
|
|
protein stabilization
|
GO:0050821 |
64 |
0.158
|
|
|
|
embryonic epithelial tube formation
|
GO:0001838 |
4 |
0.158
|
|
|
|
immune response regulating cell surface receptor signaling pathway
|
GO:0002768 |
51 |
0.156
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.148
|
Worm Fly |
|
|
regulation of response to external stimulus
|
GO:0032101 |
222 |
0.146
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.143
|
Mouse Fly |
|
|
regulation of map kinase activity
|
GO:0043405 |
108 |
0.143
|
|
|
|
actin cytoskeleton reorganization
|
GO:0031532 |
37 |
0.143
|
|
|
|
immune response activating signal transduction
|
GO:0002757 |
90 |
0.141
|
|
|
|
positive regulation of exocytosis
|
GO:0045921 |
35 |
0.139
|
|
|
|
activation of immune response
|
GO:0002253 |
114 |
0.139
|
|
|
|
tube closure
|
GO:0060606 |
3 |
0.135
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.133
|
|
|
|
positive regulation of neuroblast proliferation
|
GO:0002052 |
2 |
0.133
|
|
|
|
behavioral response to ethanol
|
GO:0048149 |
2 |
0.132
|
|
|
|
cytokinesis
|
GO:0000910 |
96 |
0.132
|
|
|
|
organophosphate biosynthetic process
|
GO:0090407 |
163 |
0.131
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
207 |
0.131
|
|
|
|
membrane organization
|
GO:0061024 |
292 |
0.126
|
Worm |
|
|
regulation of secretion
|
GO:0051046 |
194 |
0.124
|
|
|
|
generation of neurons
|
GO:0048699 |
152 |
0.122
|
Worm Fly |
|
|
oocyte development
|
GO:0048599 |
1 |
0.120
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.120
|
|
|
|
system process
|
GO:0003008 |
349 |
0.119
|
|
|
|
skin development
|
GO:0043588 |
76 |
0.118
|
|
|
|
small molecule biosynthetic process
|
GO:0044283 |
157 |
0.118
|
|
|
|
secretion by cell
|
GO:0032940 |
226 |
0.115
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.115
|
|
|
|
regulation of tor signaling
|
GO:0032006 |
30 |
0.114
|
|
|
|
cell division
|
GO:0051301 |
168 |
0.114
|
|
|
|
regulation of neuron apoptotic process
|
GO:0043523 |
35 |
0.114
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.114
|
|
|
|
cell chemotaxis
|
GO:0060326 |
112 |
0.113
|
|
|
|
immune system development
|
GO:0002520 |
195 |
0.110
|
Mouse |
|
|
positive regulation of stress activated protein kinase signaling cascade
|
GO:0070304 |
61 |
0.110
|
|
|
|
positive regulation of leukocyte proliferation
|
GO:0070665 |
48 |
0.109
|
|
|
|
regulation of protein stability
|
GO:0031647 |
87 |
0.109
|
|
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.108
|
|
|
|
endocytosis
|
GO:0006897 |
159 |
0.107
|
Worm Fly |
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.107
|
|
|
|
blood coagulation
|
GO:0007596 |
76 |
0.106
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.105
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
124 |
0.105
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
213 |
0.105
|
|
|
|
digestive tract morphogenesis
|
GO:0048546 |
56 |
0.104
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.104
|
|
|
|
membrane budding
|
GO:0006900 |
28 |
0.104
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
70 |
0.103
|
|
|
|
phospholipid biosynthetic process
|
GO:0008654 |
44 |
0.103
|
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.099
|
Mouse Worm Fly |
|
|
neurogenesis
|
GO:0022008 |
169 |
0.098
|
Worm Fly |
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.098
|
Human |
|
|
regulation of neural precursor cell proliferation
|
GO:2000177 |
4 |
0.097
|
|
|
|
cellular response to camp
|
GO:0071320 |
21 |
0.097
|
|
|
|
granulocyte migration
|
GO:0097530 |
40 |
0.096
|
|
|
|
leukocyte chemotaxis
|
GO:0030595 |
76 |
0.096
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
104 |
0.095
|
|
|
|
stress activated mapk cascade
|
GO:0051403 |
93 |
0.094
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
119 |
0.093
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.092
|
|
|
|
platelet activation
|
GO:0030168 |
44 |
0.090
|
|
|
|
regulation of response to wounding
|
GO:1903034 |
101 |
0.090
|
|
|
|
lamellipodium organization
|
GO:0097581 |
30 |
0.088
|
Mouse Fly |
|
|
single organismal cell cell adhesion
|
GO:0016337 |
148 |
0.088
|
|
|
|
negative regulation of mitotic cell cycle
|
GO:0045930 |
102 |
0.087
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.086
|
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
130 |
0.085
|
Worm |
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.084
|
|
|
|
regulation of cell cycle phase transition
|
GO:1901987 |
126 |
0.084
|
|
|
|
regulation of endocytosis
|
GO:0030100 |
72 |
0.084
|
Worm |
|
|
negative regulation of mitotic cell cycle phase transition
|
GO:1901991 |
85 |
0.083
|
|
|
|
cell junction organization
|
GO:0034330 |
79 |
0.083
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
303 |
0.082
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.082
|
|
|
|
oogenesis
|
GO:0048477 |
2 |
0.082
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.081
|
|
|
|
myeloid leukocyte migration
|
GO:0097529 |
62 |
0.080
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
177 |
0.080
|
|
|
|
actin nucleation
|
GO:0045010 |
21 |
0.079
|
Human |
|
|
positive regulation of erk1 and erk2 cascade
|
GO:0070374 |
75 |
0.079
|
|
|
|
actin filament capping
|
GO:0051693 |
4 |
0.076
|
|
|
|
immune response regulating signaling pathway
|
GO:0002764 |
97 |
0.076
|
|
|
|
establishment or maintenance of epithelial cell apical basal polarity
|
GO:0045197 |
1 |
0.075
|
|
|
|
adult behavior
|
GO:0030534 |
18 |
0.074
|
|
|
|
syncytium formation by plasma membrane fusion
|
GO:0000768 |
2 |
0.073
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.071
|
Mouse Fly |
|
|
regulation of secretion by cell
|
GO:1903530 |
177 |
0.071
|
|
|
|
positive regulation of neurogenesis
|
GO:0050769 |
49 |
0.070
|
|
|
|
glycerolipid biosynthetic process
|
GO:0045017 |
51 |
0.069
|
|
|
|
epithelial cell differentiation
|
GO:0030855 |
141 |
0.069
|
|
|
|
peptidyl serine modification
|
GO:0018209 |
106 |
0.069
|
|
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.068
|
Human |
|
|
female gamete generation
|
GO:0007292 |
2 |
0.068
|
|
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
182 |
0.068
|
|
|
|
positive regulation of immune response
|
GO:0050778 |
159 |
0.067
|
|
|
|
cardiovascular system development
|
GO:0072358 |
262 |
0.067
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.067
|
|
|
|
mitochondrion organization
|
GO:0007005 |
156 |
0.066
|
|
|
|
t cell proliferation
|
GO:0042098 |
45 |
0.065
|
|
|
|
response to nerve growth factor
|
GO:1990089 |
6 |
0.065
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.064
|
|
|
|
coagulation
|
GO:0050817 |
78 |
0.064
|
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
94 |
0.063
|
|
|
|
morphogenesis of an epithelium
|
GO:0002009 |
60 |
0.062
|
|
|
|
maintenance of cell polarity
|
GO:0030011 |
2 |
0.061
|
|
|
|
pro b cell differentiation
|
GO:0002328 |
1 |
0.061
|
|
|
|
platelet aggregation
|
GO:0070527 |
32 |
0.061
|
|
|
|
myoblast fusion
|
GO:0007520 |
1 |
0.060
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
135 |
0.060
|
|
|
|
synaptic transmission
|
GO:0007268 |
61 |
0.058
|
|
|
|
regulation of cytokinesis
|
GO:0032465 |
45 |
0.058
|
|
|
|
positive regulation of neural precursor cell proliferation
|
GO:2000179 |
2 |
0.057
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
117 |
0.057
|
Mouse |
|
|
negative regulation of cell cycle g1 s phase transition
|
GO:1902807 |
29 |
0.056
|
|
|
|
apoptotic cell clearance
|
GO:0043277 |
12 |
0.056
|
Worm |
|
|
response to peptide
|
GO:1901652 |
65 |
0.056
|
|
|
|
fibroblast growth factor receptor signaling pathway
|
GO:0008543 |
26 |
0.055
|
|
|
|
embryonic morphogenesis
|
GO:0048598 |
85 |
0.055
|
|
|
|
aorta morphogenesis
|
GO:0035909 |
1 |
0.055
|
|
|
|
regulation of lamellipodium assembly
|
GO:0010591 |
14 |
0.054
|
|
|
|
positive regulation of lymphocyte activation
|
GO:0051251 |
73 |
0.054
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
180 |
0.053
|
|
|
|
positive regulation of lamellipodium assembly
|
GO:0010592 |
9 |
0.053
|
|
|
|
neuron death
|
GO:0070997 |
65 |
0.052
|
|
|
|
blastoderm segmentation
|
GO:0007350 |
2 |
0.052
|
|
|
|
regulation of rap gtpase activity
|
GO:0032317 |
8 |
0.052
|
|
|
|
negative regulation of cell cycle process
|
GO:0010948 |
121 |
0.052
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.051
|
|
|
|
neural tube formation
|
GO:0001841 |
3 |
0.051
|
|
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.050
|
|
|
|
positive regulation of wound healing
|
GO:0090303 |
20 |
0.049
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
193 |
0.049
|
|
|
|
axon guidance
|
GO:0007411 |
12 |
0.049
|
Fly |
|
|
negative regulation of cell cycle phase transition
|
GO:1901988 |
89 |
0.048
|
|
|
|
establishment of endothelial barrier
|
GO:0061028 |
16 |
0.047
|
|
|
|
regulation of cell shape
|
GO:0008360 |
48 |
0.047
|
Fly |
|
|
tor signaling
|
GO:0031929 |
39 |
0.047
|
|
|
|
actin filament bundle organization
|
GO:0061572 |
54 |
0.047
|
|
|
|
positive regulation of small gtpase mediated signal transduction
|
GO:0051057 |
12 |
0.046
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.045
|
|
|
|
cilium organization
|
GO:0044782 |
68 |
0.045
|
|
|
|
carbohydrate transport
|
GO:0008643 |
37 |
0.044
|
|
|
|
muscle structure development
|
GO:0061061 |
98 |
0.044
|
Fly |
|
|
establishment of planar polarity
|
GO:0001736 |
3 |
0.044
|
|
|
|
regulation of mitotic cell cycle phase transition
|
GO:1901990 |
118 |
0.044
|
|
|
|
actomyosin structure organization
|
GO:0031032 |
59 |
0.044
|
|
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
144 |
0.044
|
Fly |
|
|
innate immune response
|
GO:0045087 |
178 |
0.043
|
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.042
|
|
|
|
positive regulation of cell size
|
GO:0045793 |
3 |
0.042
|
|
|
|
mitotic cell cycle phase transition
|
GO:0044772 |
162 |
0.042
|
|
|
|
growth
|
GO:0040007 |
202 |
0.042
|
Fly |
|
|
cellular response to starvation
|
GO:0009267 |
58 |
0.041
|
|
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.040
|
|
|
|
cellular response to peptide
|
GO:1901653 |
59 |
0.040
|
|
|
|
erythrocyte development
|
GO:0048821 |
3 |
0.040
|
|
|
|
neuron apoptotic process
|
GO:0051402 |
39 |
0.040
|
|
|
|
b cell activation
|
GO:0042113 |
33 |
0.040
|
|
|
|
positive regulation of mononuclear cell proliferation
|
GO:0032946 |
47 |
0.040
|
|
|
|
positive regulation of lymphocyte proliferation
|
GO:0050671 |
46 |
0.039
|
|
|
|
response to oxidative stress
|
GO:0006979 |
121 |
0.039
|
|
|
|
regulation of insulin receptor signaling pathway
|
GO:0046626 |
13 |
0.039
|
|
|
|
chemical homeostasis
|
GO:0048878 |
306 |
0.039
|
|
|
|
establishment or maintenance of actin cytoskeleton polarity
|
GO:0030950 |
1 |
0.039
|
|
|
|
hemostasis
|
GO:0007599 |
76 |
0.039
|
|
|
|
positive regulation of cell activation
|
GO:0050867 |
81 |
0.039
|
|
|
|
cellular response to nutrient levels
|
GO:0031669 |
69 |
0.039
|
|
|
|
immune response
|
GO:0006955 |
307 |
0.039
|
|
|
|
positive regulation of endopeptidase activity
|
GO:0010950 |
84 |
0.038
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.037
|
|
|
|
cell cycle g1 s phase transition
|
GO:0044843 |
80 |
0.037
|
|
|
|
inner ear morphogenesis
|
GO:0042472 |
4 |
0.037
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.036
|
Fly |
|
|
glycerophospholipid metabolic process
|
GO:0006650 |
84 |
0.036
|
|
|
|
negative regulation of growth
|
GO:0045926 |
97 |
0.036
|
|
|
|
endothelial cell differentiation
|
GO:0045446 |
26 |
0.036
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
172 |
0.036
|
|
|
|
regulation of neuronal synaptic plasticity
|
GO:0048168 |
1 |
0.036
|
|
|
|
cellular response to nitrogen compound
|
GO:1901699 |
144 |
0.036
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.036
|
|
|
|
synaptic vesicle recycling
|
GO:0036465 |
3 |
0.035
|
|
|
|
negative regulation of secretion by cell
|
GO:1903531 |
52 |
0.035
|
|
|
|
taxis
|
GO:0042330 |
157 |
0.034
|
Fly |
|
|
cell projection morphogenesis
|
GO:0048858 |
129 |
0.034
|
Mouse Worm Fly |
|
|
response to camp
|
GO:0051591 |
25 |
0.034
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
98 |
0.034
|
|
|
|
spermatid development
|
GO:0007286 |
4 |
0.034
|
|
|
|
protein kinase b signaling
|
GO:0043491 |
69 |
0.034
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.034
|
Worm |
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.033
|
|
|
|
cell morphogenesis involved in neuron differentiation
|
GO:0048667 |
44 |
0.033
|
Fly |
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.033
|
|
|
|
actin crosslink formation
|
GO:0051764 |
1 |
0.033
|
|
|
|
regulation of neurogenesis
|
GO:0050767 |
82 |
0.032
|
|
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.032
|
Human |
|
|
regulation of cell division
|
GO:0051302 |
116 |
0.032
|
|
|
|
muscle organ development
|
GO:0007517 |
56 |
0.032
|
Fly |
|
|
lymphoid progenitor cell differentiation
|
GO:0002320 |
3 |
0.032
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.032
|
|
|
|
endothelium development
|
GO:0003158 |
33 |
0.032
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.031
|
|
|
|
positive regulation of neuron differentiation
|
GO:0045666 |
40 |
0.031
|
|
|
|
neuroblast proliferation
|
GO:0007405 |
4 |
0.031
|
|
|
|
regulation of neuron death
|
GO:1901214 |
56 |
0.031
|
|
|
|
signal release
|
GO:0023061 |
70 |
0.031
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.030
|
|
|
|
negative regulation of transforming growth factor beta1 production
|
GO:0032911 |
2 |
0.030
|
|
|
|
golgi organization
|
GO:0007030 |
38 |
0.030
|
Fly |
|
|
regulation of notch signaling pathway
|
GO:0008593 |
18 |
0.030
|
|
|
|
regulation of defense response
|
GO:0031347 |
154 |
0.029
|
|
|
|
positive regulation of camp biosynthetic process
|
GO:0030819 |
35 |
0.029
|
|
|
|
response to other organism
|
GO:0051707 |
261 |
0.029
|
|
|
|
multi organism cellular process
|
GO:0044764 |
156 |
0.029
|
|
|
|
response to starvation
|
GO:0042594 |
59 |
0.029
|
|
|
|
regulation of body fluid levels
|
GO:0050878 |
99 |
0.029
|
|
|
|
immune response activating cell surface receptor signaling pathway
|
GO:0002429 |
45 |
0.029
|
|
|
|
cellular response to extracellular stimulus
|
GO:0031668 |
72 |
0.029
|
|
|
|
negative regulation of mapk cascade
|
GO:0043409 |
56 |
0.028
|
|
|
|
cell aging
|
GO:0007569 |
52 |
0.028
|
|
|
|
granulocyte chemotaxis
|
GO:0071621 |
37 |
0.028
|
|
|
|
response to caffeine
|
GO:0031000 |
3 |
0.028
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
125 |
0.028
|
|
|
|
endomembrane system organization
|
GO:0010256 |
196 |
0.028
|
Fly |
|
|
fibroblast apoptotic process
|
GO:0044346 |
8 |
0.027
|
|
|
|
negative regulation of rho gtpase activity
|
GO:0034259 |
4 |
0.027
|
|
|
|
cell junction assembly
|
GO:0034329 |
67 |
0.027
|
|
|
|
cilium morphogenesis
|
GO:0060271 |
75 |
0.027
|
|
|
|
lipid localization
|
GO:0010876 |
106 |
0.027
|
|
|
|
establishment of tissue polarity
|
GO:0007164 |
3 |
0.027
|
|
|
|
vesicle organization
|
GO:0016050 |
62 |
0.027
|
|
|
|
protein autophosphorylation
|
GO:0046777 |
123 |
0.027
|
|
|
|
establishment or maintenance of cell polarity
|
GO:0007163 |
31 |
0.026
|
|
|
|
negative regulation of protein polymerization
|
GO:0032272 |
16 |
0.026
|
|
|
|
monosaccharide transport
|
GO:0015749 |
32 |
0.026
|
|
|
|
protein secretion
|
GO:0009306 |
98 |
0.026
|
|
|
|
response to growth factor
|
GO:0070848 |
205 |
0.026
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.026
|
|
|
|
digestive system development
|
GO:0055123 |
75 |
0.026
|
|
|
|
response to wounding
|
GO:0009611 |
168 |
0.026
|
|
|
|
hormone secretion
|
GO:0046879 |
65 |
0.026
|
|
|
|
locomotory behavior
|
GO:0007626 |
1 |
0.026
|
|
|
|
receptor mediated endocytosis
|
GO:0006898 |
84 |
0.025
|
Worm |
|
|
negative regulation of cytoskeleton organization
|
GO:0051494 |
45 |
0.025
|
|
|
|
response to uv
|
GO:0009411 |
73 |
0.025
|
|
|
|
anterior posterior axis specification embryo
|
GO:0008595 |
2 |
0.025
|
|
|
|
regulation of phagocytosis engulfment
|
GO:0060099 |
2 |
0.025
|
Worm |
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.025
|
|
|
|
tube morphogenesis
|
GO:0035239 |
95 |
0.025
|
|
|
|
phosphatidylinositol 3 phosphate biosynthetic process
|
GO:0036092 |
3 |
0.025
|
|
|
|
phagocytosis engulfment
|
GO:0006911 |
7 |
0.025
|
Worm |
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.025
|
|
|
|
anterior posterior axis specification
|
GO:0009948 |
2 |
0.025
|
|
|
|
negative regulation of actin filament depolymerization
|
GO:0030835 |
5 |
0.025
|
|
|
|
organelle fission
|
GO:0048285 |
149 |
0.025
|
|
|
|
cortical cytoskeleton organization
|
GO:0030865 |
9 |
0.024
|
Fly |
|
|
regulation of cell development
|
GO:0060284 |
161 |
0.024
|
|
|
|
developmental cell growth
|
GO:0048588 |
18 |
0.024
|
Fly |
|
|
response to radiation
|
GO:0009314 |
151 |
0.024
|
|
|
|
tripartite regional subdivision
|
GO:0007351 |
2 |
0.023
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
207 |
0.023
|
|
|
|
myotube differentiation
|
GO:0014902 |
22 |
0.023
|
|
|
|
developmental growth involved in morphogenesis
|
GO:0060560 |
23 |
0.023
|
Fly |
|
|
positive regulation of locomotion
|
GO:0040017 |
186 |
0.023
|
|
|
|
regulation of myosin light chain phosphatase activity
|
GO:0035507 |
3 |
0.023
|
|
|
|
central nervous system development
|
GO:0007417 |
123 |
0.023
|
Fly |
|
|
compound eye development
|
GO:0048749 |
1 |
0.023
|
|
|
|
epidermis development
|
GO:0008544 |
59 |
0.023
|
|
|
|
cell migration involved in gastrulation
|
GO:0042074 |
1 |
0.023
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
140 |
0.023
|
|
|
|
histone modification
|
GO:0016570 |
251 |
0.023
|
|
|
|
glycerolipid metabolic process
|
GO:0046486 |
107 |
0.022
|
|
|
|
positive regulation of secretion
|
GO:0051047 |
116 |
0.022
|
|
|
|
regulation of growth
|
GO:0040008 |
165 |
0.022
|
|
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.022
|
|
|
|
meiotic chromosome segregation
|
GO:0045132 |
4 |
0.022
|
|
|
|
stress fiber assembly
|
GO:0043149 |
40 |
0.022
|
|
|
|
single organism reproductive process
|
GO:0044702 |
98 |
0.021
|
Worm |
|
|
t cell activation
|
GO:0042110 |
99 |
0.021
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.020
|
|
|
|
negative regulation of transport
|
GO:0051051 |
176 |
0.020
|
|
|
|
cytokine production
|
GO:0001816 |
247 |
0.020
|
|
|
|
single organism carbohydrate metabolic process
|
GO:0044723 |
193 |
0.020
|
|
|
|
positive regulation of endocytosis
|
GO:0045807 |
42 |
0.020
|
Worm |
|
|
cell cycle phase transition
|
GO:0044770 |
173 |
0.020
|
|
|
|
cell part morphogenesis
|
GO:0032990 |
137 |
0.020
|
Mouse Worm Fly |
|
|
negative regulation of catabolic process
|
GO:0009895 |
104 |
0.020
|
|
|
|
regulation of synaptic plasticity
|
GO:0048167 |
3 |
0.020
|
|
|
|
leukocyte mediated immunity
|
GO:0002443 |
59 |
0.019
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
232 |
0.019
|
|
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.019
|
|
|
|
neutrophil migration
|
GO:1990266 |
25 |
0.019
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
162 |
0.019
|
|
|
|
negative regulation of map kinase activity
|
GO:0043407 |
27 |
0.019
|
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
127 |
0.019
|
|
|
|
myeloid cell development
|
GO:0061515 |
5 |
0.019
|
Mouse |
|
|
erythrocyte homeostasis
|
GO:0034101 |
31 |
0.019
|
|
|
|
embryo development ending in birth or egg hatching
|
GO:0009792 |
34 |
0.019
|
Mouse Worm |
|
|
embryo development
|
GO:0009790 |
123 |
0.019
|
Mouse Worm |
|
|
cellular metal ion homeostasis
|
GO:0006875 |
146 |
0.019
|
|
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
117 |
0.019
|
|
|
|
nuclear division
|
GO:0000280 |
128 |
0.019
|
|
|
|
gastrulation
|
GO:0007369 |
51 |
0.019
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.018
|
|
|
|
hormone transport
|
GO:0009914 |
68 |
0.018
|
|
|
|
notch signaling pathway
|
GO:0007219 |
31 |
0.018
|
|
|
|
reproduction
|
GO:0000003 |
63 |
0.018
|
Worm |
|
|
epidermal growth factor receptor signaling pathway
|
GO:0007173 |
39 |
0.018
|
|
|
|
establishment or maintenance of apical basal cell polarity
|
GO:0035088 |
2 |
0.018
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.018
|
|
|
|
cellular cation homeostasis
|
GO:0030003 |
163 |
0.018
|
|
|
|
response to light stimulus
|
GO:0009416 |
87 |
0.018
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
136 |
0.018
|
|
