Homo sapiens

24 known processes

ARHGEF12

Rho guanine nucleotide exchange factor (GEF) 12

(Aliases: PRO2792,KIAA0382,LARG,DKFZp686O2372)

ARHGEF12 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
positive regulation of steroid hormone biosynthetic process GO:0090031 2 0.990
cell differentiation in spinal cord GO:0021515 1 0.814
ventral spinal cord development GO:0021517 1 0.796
rho protein signal transduction GO:0007266 26 0.683
Human Fly
positive regulation of hormone biosynthetic process GO:0046886 4 0.625
hormone metabolic process GO:0042445 61 0.596
spinal cord development GO:0021510 4 0.541
forebrain generation of neurons GO:0021872 3 0.504
actin cytoskeleton organization GO:0030036 207 0.442
Fly
ras protein signal transduction GO:0007265 73 0.436
Human Fly
actin filament based movement GO:0030048 17 0.434
Fly
embryonic camera type eye development GO:0031076 2 0.378
positive regulation of catabolic process GO:0009896 310 0.307
Fly
negative regulation of protein metabolic process GO:0051248 391 0.283
mating GO:0007618 1 0.265
positive regulation of glycogen metabolic process GO:0070875 10 0.256
inner ear morphogenesis GO:0042472 4 0.247
wound healing GO:0042060 115 0.246
axis elongation GO:0003401 4 0.239
actin filament based process GO:0030029 224 0.237
Fly
multicellular organismal aging GO:0010259 3 0.231
tissue morphogenesis GO:0048729 96 0.228
Fly
cellular amine metabolic process GO:0044106 41 0.228
cytokinesis GO:0000910 96 0.227
prostate gland morphogenesis GO:0060512 1 0.219
morphogenesis of an epithelium GO:0002009 60 0.219
Fly
cell development GO:0048468 328 0.217
Fly
cell morphogenesis involved in differentiation GO:0000904 144 0.205
Fly
regulation of cellular ketone metabolic process GO:0010565 50 0.200
semicircular canal development GO:0060872 1 0.199
ribonucleotide catabolic process GO:0009261 405 0.186
Fly
neuron projection regeneration GO:0031102 1 0.180
negative regulation of transport GO:0051051 176 0.178
positive regulation of organelle organization GO:0010638 195 0.174
regulation of purine nucleotide catabolic process GO:0033121 205 0.167
Fly
establishment of tissue polarity GO:0007164 3 0.166
positive regulation of hydrolase activity GO:0051345 331 0.166
Fly
regulation of transferase activity GO:0051338 355 0.164
wnt signaling pathway GO:0016055 156 0.164
post embryonic development GO:0009791 2 0.160
Fly
semicircular canal morphogenesis GO:0048752 1 0.160
membrane organization GO:0061024 292 0.157
positive regulation of gtpase activity GO:0043547 166 0.156
Fly
negative regulation of phosphorus metabolic process GO:0010563 267 0.154
regulation of small gtpase mediated signal transduction GO:0051056 156 0.154
Fly
g protein coupled receptor signaling pathway GO:0007186 207 0.151
regulation of nucleoside metabolic process GO:0009118 209 0.149
Fly
steroid biosynthetic process GO:0006694 46 0.144
female gamete generation GO:0007292 2 0.144
negative regulation of catalytic activity GO:0043086 335 0.144
mitotic cell cycle GO:0000278 326 0.142
generation of neurons GO:0048699 152 0.138
Fly
regulation of cell migration GO:0030334 289 0.137
positive regulation of cellular component organization GO:0051130 376 0.136
determination of adult lifespan GO:0008340 2 0.135
regulation of actin cytoskeleton organization GO:0032956 116 0.131
regulation of wnt signaling pathway planar cell polarity pathway GO:2000095 2 0.130
bleb assembly GO:0032060 6 0.130
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.129
ion transmembrane transport GO:0034220 338 0.128
nuclear division GO:0000280 128 0.126
regulation of cell differentiation GO:0045595 393 0.125
Fly
cellular response to ph GO:0071467 9 0.123
tube morphogenesis GO:0035239 95 0.122
Fly
regulation of growth GO:0040008 165 0.122
cerebral cortex cell migration GO:0021795 3 0.121
regulation of hormone levels GO:0010817 125 0.119
regulation of actin filament based process GO:0032970 141 0.118
positive regulation of gtp catabolic process GO:0033126 166 0.115
Fly
regulation of locomotion GO:0040012 329 0.113
monocarboxylic acid metabolic process GO:0032787 185 0.112
regulation of feeding behavior GO:0060259 3 0.110
ossification involved in bone maturation GO:0043931 4 0.109
microtubule cytoskeleton organization GO:0000226 176 0.109
circadian sleep wake cycle GO:0042745 2 0.108
negative regulation of transferase activity GO:0051348 124 0.108
bone maturation GO:0070977 5 0.108
locomotory behavior GO:0007626 1 0.108
protein heterotetramerization GO:0051290 3 0.107
actin mediated cell contraction GO:0070252 12 0.106
Fly
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.106
regeneration GO:0031099 4 0.105
purine ribonucleoside catabolic process GO:0046130 398 0.104
Fly
cellular response to endogenous stimulus GO:0071495 336 0.104
oogenesis GO:0048477 2 0.101
carbohydrate metabolic process GO:0005975 207 0.101
viral process GO:0016032 146 0.100
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 71 0.100
circadian sleep wake cycle process GO:0022410 2 0.100
neurotransmitter secretion GO:0007269 4 0.098
acetylcholine transport GO:0015870 1 0.098
positive regulation of developmental process GO:0051094 314 0.098
regulation of proteolysis GO:0030162 293 0.098
anatomical structure formation involved in morphogenesis GO:0048646 284 0.097
Fly
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.097
Fly
regulation of lipid biosynthetic process GO:0046890 47 0.095
cell morphogenesis GO:0000902 296 0.095
Fly
regulation of cellular component biogenesis GO:0044087 281 0.094
regulation of cellular component movement GO:0051270 334 0.094
epithelium development GO:0060429 227 0.094
Fly
regulation of ras gtpase activity GO:0032318 128 0.094
Fly
fatty acid metabolic process GO:0006631 115 0.091
cell projection organization GO:0030030 252 0.090
Fly
regulation of cytoskeleton organization GO:0051493 177 0.090
guanosine containing compound metabolic process GO:1901068 244 0.089
Fly
regulation of establishment of protein localization GO:0070201 242 0.089
protein catabolic process GO:0030163 325 0.088
rhythmic behavior GO:0007622 2 0.087
mitotic cell cycle process GO:1903047 286 0.087
cellular response to dna damage stimulus GO:0006974 379 0.086
nervous system development GO:0007399 293 0.085
Fly
cellular protein catabolic process GO:0044257 261 0.084
regulation of circadian sleep wake cycle GO:0042749 2 0.083
positive regulation of cellular catabolic process GO:0031331 284 0.083
Fly
striated muscle cell apoptotic process GO:0010658 3 0.081
secretion by cell GO:0032940 226 0.079
response to cocaine GO:0042220 1 0.079
actomyosin structure organization GO:0031032 59 0.078
glycogen metabolic process GO:0005977 22 0.078
circadian sleep wake cycle sleep GO:0050802 2 0.078
regulation of protein transport GO:0051223 213 0.077
regulation of rho gtpase activity GO:0032319 66 0.076
Fly
maintenance of location GO:0051235 112 0.075
regulation of hormone metabolic process GO:0032350 14 0.075
negative regulation of multicellular organismal process GO:0051241 317 0.073
oxidation reduction process GO:0055114 396 0.073
negative regulation of protein transport GO:0051224 75 0.072
nucleoside triphosphate metabolic process GO:0009141 422 0.072
Fly
cell type specific apoptotic process GO:0097285 125 0.071
asymmetric stem cell division GO:0098722 1 0.071
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.071
Fly
establishment of planar polarity GO:0001736 3 0.071
morphogenesis of a polarized epithelium GO:0001738 3 0.071
cellular component morphogenesis GO:0032989 314 0.071
Fly
negative regulation of endopeptidase activity GO:0010951 84 0.071
regulation of steroid biosynthetic process GO:0050810 23 0.070
regulation of nervous system development GO:0051960 88 0.069
Fly
regulation of cellular component size GO:0032535 82 0.069
proteasomal protein catabolic process GO:0010498 176 0.069
regulation of circadian sleep wake cycle sleep GO:0045187 2 0.069
negative regulation of cell death GO:0060548 345 0.068
regulation of intracellular transport GO:0032386 195 0.067
purine containing compound catabolic process GO:0072523 411 0.067
Fly
glycogen biosynthetic process GO:0005978 16 0.067
negative regulation of protein processing GO:0010955 142 0.066
peripheral nervous system development GO:0007422 2 0.066
regulation of autophagic vacuole assembly GO:2000785 6 0.065
positive regulation of glycogen biosynthetic process GO:0045725 10 0.064
cortisol secretion GO:0043400 4 0.064
regulation of cell morphogenesis involved in differentiation GO:0010769 83 0.063
Fly
regulation of cell motility GO:2000145 299 0.063
mechanosensory behavior GO:0007638 4 0.062
Worm
negative regulation of protein maturation GO:1903318 142 0.061
stem cell division GO:0017145 2 0.061
cell division GO:0051301 168 0.061
regulation of protein maturation GO:1903317 150 0.061
regulation of neurogenesis GO:0050767 82 0.061
Fly
lipid metabolic process GO:0006629 381 0.061
nucleoside triphosphate catabolic process GO:0009143 394 0.061
Fly
cation transport GO:0006812 331 0.060
endomembrane system organization GO:0010256 196 0.060
establishment or maintenance of epithelial cell apical basal polarity GO:0045197 1 0.060
embryonic morphogenesis GO:0048598 85 0.060
Fly
tissue regeneration GO:0042246 3 0.060
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.060
Fly
embryonic viscerocranium morphogenesis GO:0048703 1 0.060
regulation of protein processing GO:0070613 150 0.059
actin filament organization GO:0007015 128 0.059
Fly
regulation of protein localization GO:0032880 296 0.059
positive regulation of lipid biosynthetic process GO:0046889 22 0.059
positive regulation of rho protein signal transduction GO:0035025 4 0.059
Fly
axon regeneration GO:0031103 1 0.059
secondary metabolic process GO:0019748 17 0.059
forebrain development GO:0030900 26 0.058
oocyte development GO:0048599 1 0.058
anatomical structure homeostasis GO:0060249 100 0.058
negative regulation of feeding behavior GO:2000252 1 0.057
response to wounding GO:0009611 168 0.057
steroid metabolic process GO:0008202 94 0.057
negative regulation of cellular component organization GO:0051129 235 0.057
negative regulation of secretion GO:0051048 58 0.056
tube development GO:0035295 125 0.056
Fly
interspecies interaction between organisms GO:0044419 156 0.056
response to ph GO:0009268 12 0.055
regulation of cellular amino acid metabolic process GO:0006521 6 0.054
morphogenesis of embryonic epithelium GO:0016331 4 0.054
Fly
nucleoside phosphate catabolic process GO:1901292 412 0.054
Fly
mitotic nuclear division GO:0007067 119 0.054
negative regulation of glycogen metabolic process GO:0070874 4 0.053
nucleoside catabolic process GO:0009164 408 0.053
Fly
regulation of neural precursor cell proliferation GO:2000177 4 0.053
cardiovascular system development GO:0072358 262 0.053
response to abiotic stimulus GO:0009628 336 0.052
Worm
positive regulation of small gtpase mediated signal transduction GO:0051057 12 0.052
Fly
cellular carbohydrate biosynthetic process GO:0034637 21 0.052
positive regulation of cell migration GO:0030335 172 0.052
cellular amino acid metabolic process GO:0006520 116 0.052
organophosphate catabolic process GO:0046434 430 0.052
Fly
single organism carbohydrate metabolic process GO:0044723 193 0.051
neuromuscular junction development GO:0007528 3 0.051
negative regulation of phosphorylation GO:0042326 174 0.051
angiogenesis GO:0001525 147 0.051
growth GO:0040007 202 0.050
Fly
cellular polysaccharide biosynthetic process GO:0033692 21 0.050
prostate gland development GO:0030850 3 0.050
pattern specification process GO:0007389 43 0.049
ubiquitin dependent protein catabolic process GO:0006511 206 0.049
establishment or maintenance of cytoskeleton polarity GO:0030952 3 0.049
negative regulation of cellular amine metabolic process GO:0033239 3 0.048
head development GO:0060322 108 0.048
positive regulation of nucleotide catabolic process GO:0030813 185 0.048
Fly
lipid biosynthetic process GO:0008610 177 0.048
regulation of glucan biosynthetic process GO:0010962 14 0.048
glucocorticoid secretion GO:0035933 4 0.048
response to nitrogen compound GO:1901698 184 0.048
establishment of protein localization to organelle GO:0072594 172 0.047
positive regulation of locomotion GO:0040017 186 0.047
sleep GO:0030431 2 0.047
sex determination GO:0007530 3 0.046
peptide transport GO:0015833 74 0.046
positive regulation of protein complex assembly GO:0031334 86 0.045
positive regulation of protein kinase activity GO:0045860 190 0.045
regulation of glucose metabolic process GO:0010906 28 0.045
glucose homeostasis GO:0042593 31 0.044
regulation of mitosis GO:0007088 63 0.044
negative regulation of phosphate metabolic process GO:0045936 267 0.044
positive regulation of protein phosphorylation GO:0001934 313 0.044
regulation of glycogen biosynthetic process GO:0005979 14 0.043
regulation of non canonical wnt signaling pathway GO:2000050 4 0.043
positive regulation of mesenchymal cell proliferation GO:0002053 2 0.043
neuron differentiation GO:0030182 138 0.043
Fly
regulation of cell cycle process GO:0010564 266 0.043
positive regulation of amine transport GO:0051954 2 0.043
neuroblast proliferation GO:0007405 4 0.043
regulation of wound healing GO:0061041 56 0.043
negative regulation of protein phosphorylation GO:0001933 140 0.043
hormone biosynthetic process GO:0042446 22 0.042
protein maturation GO:0051604 233 0.042
circadian behavior GO:0048512 2 0.042
multi organism cellular process GO:0044764 156 0.042
ribonucleoside triphosphate catabolic process GO:0009203 391 0.042
Fly
actin filament bundle assembly GO:0051017 54 0.042
positive regulation of glucose metabolic process GO:0010907 12 0.042
regulation of actin filament polymerization GO:0030833 50 0.042
positive regulation of steroid metabolic process GO:0045940 13 0.042
response to alkaline ph GO:0010446 2 0.041
positive regulation of wound healing GO:0090303 20 0.041
cellular glucan metabolic process GO:0006073 22 0.040
response to hormone GO:0009725 175 0.040
regulation of purine nucleotide metabolic process GO:1900542 264 0.040
Fly
establishment of protein localization to membrane GO:0090150 121 0.040
regulation of endopeptidase activity GO:0052548 170 0.040
regulation of anatomical structure size GO:0090066 101 0.039
acetylcholine secretion GO:0061526 1 0.039
cellular ketone metabolic process GO:0042180 80 0.039
negative regulation of proteolysis GO:0045861 132 0.039
regulation of nucleotide metabolic process GO:0006140 269 0.039
Fly
purine nucleoside catabolic process GO:0006152 398 0.039
Fly
endosomal transport GO:0016197 129 0.039
guanosine containing compound catabolic process GO:1901069 239 0.038
Fly
positive regulation of phosphorylation GO:0042327 394 0.037
sensory perception of mechanical stimulus GO:0050954 37 0.037
Worm
negative regulation of apoptotic process GO:0043066 316 0.037
single organism cellular localization GO:1902580 332 0.037
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.037
oocyte differentiation GO:0009994 2 0.036
negative regulation of protein modification process GO:0031400 200 0.036
ribonucleoside catabolic process GO:0042454 406 0.036
Fly
response to acid chemical GO:0001101 66 0.036
immune response GO:0006955 307 0.036
positive regulation of nervous system development GO:0051962 54 0.036
digestive system development GO:0055123 75 0.036
Fly
regulation of gtp catabolic process GO:0033124 180 0.036
Fly
cell cycle phase transition GO:0044770 173 0.036
response to decreased oxygen levels GO:0036293 96 0.036
gtp catabolic process GO:0006184 237 0.035
Fly
regulation of organelle assembly GO:1902115 40 0.035
purine ribonucleoside metabolic process GO:0046128 437 0.035
Fly
negative regulation of cellular protein metabolic process GO:0032269 353 0.035
metal ion transport GO:0030001 272 0.035
ion homeostasis GO:0050801 230 0.035
positive regulation of respiratory burst GO:0060267 5 0.035
neurological system process GO:0050877 163 0.035
Worm
regulation of secretion by cell GO:1903530 177 0.035
regulation of glycogen metabolic process GO:0070873 15 0.035
negative regulation of hydrolase activity GO:0051346 182 0.034
cellular polysaccharide metabolic process GO:0044264 27 0.034
nucleotide catabolic process GO:0009166 408 0.034
Fly
telencephalon development GO:0021537 17 0.034
cytoplasmic transport GO:0016482 379 0.034
positive regulation of hormone metabolic process GO:0032352 6 0.034
cellular macromolecule catabolic process GO:0044265 380 0.034
regulation of steroid metabolic process GO:0019218 32 0.034
somatic muscle development GO:0007525 1 0.034
regulation of actin polymerization or depolymerization GO:0008064 56 0.034
purine nucleotide catabolic process GO:0006195 405 0.034
Fly
regulation of intracellular protein transport GO:0033157 123 0.033
microtubule based process GO:0007017 210 0.033
glucan metabolic process GO:0044042 22 0.033
regulation of protein complex assembly GO:0043254 147 0.033
protein targeting GO:0006605 187 0.033
regulation of reactive oxygen species biosynthetic process GO:1903426 3 0.033
regulation of cytoplasmic transport GO:1903649 149 0.033
purine ribonucleotide catabolic process GO:0009154 404 0.033
Fly
neuron development GO:0048666 113 0.033
Fly
sodium ion transport GO:0006814 61 0.032
purine nucleoside triphosphate metabolic process GO:0009144 412 0.032
Fly
actin filament bundle organization GO:0061572 54 0.032
cellular response to histamine GO:0071420 3 0.032
plasma membrane organization GO:0007009 115 0.032
regulation of mitotic metaphase anaphase transition GO:0030071 26 0.032
positive regulation of steroid biosynthetic process GO:0010893 6 0.032
regulation of lipid metabolic process GO:0019216 96 0.032
biological adhesion GO:0022610 331 0.032
regulation of cell growth GO:0001558 135 0.032
single organism membrane organization GO:0044802 268 0.032
positive regulation of organ growth GO:0046622 2 0.032
glycosyl compound catabolic process GO:1901658 413 0.032
Fly
polysaccharide biosynthetic process GO:0000271 27 0.032
organic hydroxy compound metabolic process GO:1901615 147 0.032
regulation of cell division GO:0051302 116 0.032
regulation of protein kinase activity GO:0045859 289 0.031
mitotic cytokinetic process GO:1902410 2 0.031
purine nucleoside triphosphate catabolic process GO:0009146 392 0.031
Fly
positive regulation of secretion GO:0051047 116 0.031
negative regulation of autophagy GO:0010507 14 0.031
negative regulation of peptidase activity GO:0010466 91 0.031
regulation of kinase activity GO:0043549 314 0.031
sodium ion transmembrane transport GO:0035725 59 0.030
anion transmembrane transport GO:0098656 76 0.030
urogenital system development GO:0001655 65 0.030
response to organonitrogen compound GO:0010243 156 0.030
regulation of protein serine threonine kinase activity GO:0071900 179 0.030
organelle fission GO:0048285 149 0.030
cellular response to organonitrogen compound GO:0071417 124 0.030
central nervous system development GO:0007417 123 0.030
response to lipid GO:0033993 206 0.030
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 89 0.030
regulation of cell cycle GO:0051726 393 0.030
positive regulation of i kappab kinase nf kappab signaling GO:0043123 132 0.030
regulation of cellular carbohydrate metabolic process GO:0010675 47 0.030
negative regulation of protein kinase b signaling GO:0051898 17 0.030
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.029
positive regulation of protein serine threonine kinase activity GO:0071902 119 0.029
brain development GO:0007420 97 0.029
regulation of vesicle mediated transport GO:0060627 130 0.029
modification dependent protein catabolic process GO:0019941 209 0.029
cellular lipid metabolic process GO:0044255 303 0.029
endosome to lysosome transport GO:0008333 21 0.029
positive regulation of cell projection organization GO:0031346 64 0.029
myosin filament assembly GO:0031034 2 0.029
negative regulation of wnt signaling pathway GO:0030178 69 0.029
regulation of carbohydrate metabolic process GO:0006109 54 0.029
negative regulation of circadian rhythm GO:0042754 1 0.029
cation transmembrane transport GO:0098655 238 0.028
regulation of hormone biosynthetic process GO:0046885 10 0.028
regulation of mitotic cell cycle phase transition GO:1901990 118 0.028
gtp metabolic process GO:0046039 239 0.028
Fly
mitotic sister chromatid separation GO:0051306 18 0.028
peptidyl tyrosine modification GO:0018212 170 0.028
response to organic cyclic compound GO:0014070 204 0.028
positive regulation of synaptic transmission GO:0050806 4 0.028
positive regulation of cellular component biogenesis GO:0044089 158 0.028
cardiac muscle cell apoptotic process GO:0010659 3 0.028
tripartite regional subdivision GO:0007351 2 0.028
associative learning GO:0008306 1 0.028
vesicle mediated transport GO:0016192 371 0.028
protein localization to plasma membrane GO:0072659 93 0.028
regulation of endocytosis GO:0030100 72 0.028
vacuole organization GO:0007033 44 0.028
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.027
response to oxygen levels GO:0070482 100 0.027
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.027
positive regulation of carbohydrate metabolic process GO:0045913 21 0.027
melanin metabolic process GO:0006582 1 0.027
chromatin organization GO:0006325 351 0.027
digestive tract development GO:0048565 75 0.027
Fly
regulation of steroid hormone biosynthetic process GO:0090030 6 0.027
carboxylic acid transport GO:0046942 63 0.027
dna damage checkpoint GO:0000077 68 0.027
cell projection morphogenesis GO:0048858 129 0.027
Fly
positive regulation of organelle assembly GO:1902117 17 0.027
peptidyl tyrosine phosphorylation GO:0018108 170 0.027
regulation of glucocorticoid secretion GO:2000849 4 0.027
regulation of nucleocytoplasmic transport GO:0046822 98 0.027
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.027
myoblast fusion GO:0007520 1 0.027
regulation of glucose import in response to insulin stimulus GO:2001273 4 0.027
cell part morphogenesis GO:0032990 137 0.027
Fly
myeloid cell differentiation GO:0030099 117 0.027
regulation of gtpase activity GO:0043087 180 0.027
Fly
stress fiber assembly GO:0043149 40 0.027
chemical homeostasis GO:0048878 306 0.026
intracellular steroid hormone receptor signaling pathway GO:0030518 61 0.026
nitrogen compound transport GO:0071705 191 0.026
ribonucleoside triphosphate metabolic process GO:0009199 412 0.026
Fly
regulation of rho protein signal transduction GO:0035023 79 0.026
Fly
negative regulation of programmed cell death GO:0043069 321 0.026
immune effector process GO:0002252 159 0.026
interaction with host GO:0051701 42 0.026
carbohydrate catabolic process GO:0016052 36 0.026
positive regulation of glucose import in response to insulin stimulus GO:2001275 3 0.026
semaphorin plexin signaling pathway GO:0071526 4 0.026
protein localization to membrane GO:0072657 160 0.026
autophagy GO:0006914 88 0.026
reproductive process GO:0022414 106 0.026
Worm Fly
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.026
chemotaxis GO:0006935 157 0.026
epithelial cell differentiation GO:0030855 141 0.026
blood vessel development GO:0001568 172 0.026
syncytium formation by plasma membrane fusion GO:0000768 2 0.026
glycoprotein biosynthetic process GO:0009101 91 0.026
anatomical structure maturation GO:0071695 9 0.025
circulatory system development GO:0072359 262 0.025
positive regulation of cell division GO:0051781 59 0.025
response to extracellular stimulus GO:0009991 85 0.025
pallium development GO:0021543 10 0.025
positive regulation of lipid metabolic process GO:0045834 50 0.025
single organism reproductive process GO:0044702 98 0.025
Fly
maintenance of protein location GO:0045185 57 0.025
negative regulation of phagocytosis GO:0050765 4 0.025
negative regulation of circadian sleep wake cycle sleep GO:0042321 1 0.025
regulation of peptidyl tyrosine phosphorylation GO:0050730 108 0.025
regulation of mapk cascade GO:0043408 262 0.025
intracellular receptor signaling pathway GO:0030522 104 0.024
cellular carbohydrate metabolic process GO:0044262 84 0.024
carbohydrate transport GO:0008643 37 0.024
rna processing GO:0006396 255 0.024
mitotic cell cycle phase transition GO:0044772 162 0.024
mitotic cytokinesis GO:0000281 19 0.024
tor signaling GO:0031929 39 0.024
platelet formation GO:0030220 4 0.024
regulation of wnt signaling pathway GO:0030111 123 0.024
behavior GO:0007610 112 0.024
Worm
chromosome segregation GO:0007059 114 0.024
cellular response to lipid GO:0071396 127 0.024
hexose metabolic process GO:0019318 55 0.023
intracellular protein transport GO:0006886 270 0.023
regulation of polysaccharide metabolic process GO:0032881 21 0.023
cellular response to external stimulus GO:0071496 111 0.023
maintenance of location in cell GO:0051651 62 0.023
cell growth GO:0016049 160 0.023
Fly
neurogenesis GO:0022008 169 0.023
Fly
dna integrity checkpoint GO:0031570 71 0.023
regulation of cell development GO:0060284 161 0.023
Fly
regulation of amine transport GO:0051952 5 0.023
regulation of carbohydrate biosynthetic process GO:0043255 27 0.022
neuron projection development GO:0031175 106 0.022
Fly
trabecula morphogenesis GO:0061383 2 0.022
cell junction organization GO:0034330 79 0.022
negative regulation of cytoplasmic transport GO:1903650 46 0.022
single organism carbohydrate catabolic process GO:0044724 33 0.022
meiosis i GO:0007127 4 0.022
ear development GO:0043583 14 0.022
response to radiation GO:0009314 151 0.022
negative regulation of secretion by cell GO:1903531 52 0.022
response to oxygen containing compound GO:1901700 369 0.022
golgi vesicle transport GO:0048193 80 0.022
regulation of chromosome organization GO:0033044 103 0.022
transmembrane transport GO:0055085 399 0.022
regulation of cellular amine metabolic process GO:0033238 11 0.022
modification of morphology or physiology of other organism GO:0035821 43 0.022
adult locomotory behavior GO:0008344 1 0.022
cofactor metabolic process GO:0051186 87 0.021
lipid modification GO:0030258 84 0.021
amine metabolic process GO:0009308 44 0.021
negative regulation of cytoskeleton organization GO:0051494 45 0.021
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 91 0.021
regulation of stress fiber assembly GO:0051492 32 0.021
histone modification GO:0016570 251 0.021
response to oxidative stress GO:0006979 121 0.021
regulation of cell shape GO:0008360 48 0.021
Fly
positive regulation of cytokinesis GO:0032467 29 0.021
ameboidal type cell migration GO:0001667 135 0.021
negative regulation of intracellular signal transduction GO:1902532 183 0.021
negative chemotaxis GO:0050919 11 0.021
positive regulation of cell proliferation GO:0008284 301 0.021
regulation of protein catabolic process GO:0042176 155 0.021
regulation of ion transport GO:0043269 189 0.021
multicellular organismal homeostasis GO:0048871 67 0.021
anterior posterior axis specification GO:0009948 2 0.021
multi organism reproductive process GO:0044703 54 0.021
Worm Fly
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.021
Fly
negative regulation of cell proliferation GO:0008285 228 0.020
polysaccharide metabolic process GO:0005976 33 0.020

ARHGEF12 disease predictions

Disease DO term ID Size Probability Func Analog Org
kidney disease DOID:557 36 0.068
urinary system disease DOID:18 40 0.068
cancer DOID:162 167 0.026
disease of cellular proliferation DOID:14566 174 0.026
organ system cancer DOID:0050686 164 0.026
disease of metabolism DOID:0014667 295 0.024
carbohydrate metabolism disease DOID:0050013 32 0.024
glucose metabolism disease DOID:4194 32 0.024
acquired metabolic disease DOID:0060158 58 0.024