IMP

Process View

5 genes annotated in human

bone maturation

A developmental process, independent of morphogenetic (shape) change, that is required for bone to attain its fully functional state.

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Known genes in the process in human Include functional analogs

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Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "bone maturation" (in gray)

Name	Description	Probability	Func Analog Organism
CSH1	chorionic somatomammotropin hormone 1 (placental lactogen)	0.881	Human
GH1	growth hormone 1	0.868
ARHGEF11	Rho guanine nucleotide exchange factor (GEF) 11	0.700
BMPR1A	bone morphogenetic protein receptor, type IA	0.576
RND1	Rho family GTPase 1	0.318
CSH2	chorionic somatomammotropin hormone 2	0.294	Human
ITGB1BP3	integrin beta 1 binding protein 3	0.274
CSHL1	chorionic somatomammotropin hormone-like 1	0.258	Human
GH2	growth hormone 2	0.197	Human
ROCK1	Rho-associated, coiled-coil containing protein kinase 1	0.167
ARHGAP1	Rho GTPase activating protein 1	0.165
ARHGEF12	Rho guanine nucleotide exchange factor (GEF) 12	0.108
IGF2R	insulin-like growth factor 2 receptor	0.066
FSTL1	follistatin-like 1	0.043
FAF1	Fas (TNFRSF6) associated factor 1	0.037
PTPRC	protein tyrosine phosphatase, receptor type, C	0.027
SORBS1	sorbin and SH3 domain containing 1	0.027
DIAPH1	diaphanous homolog 1 (Drosophila)	0.026
RAC1	ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)	0.023
FGF1	fibroblast growth factor 1 (acidic)	0.020
PLXNB2	plexin B2	0.017
PLXNB1	plexin B1	0.015	Mouse
SMURF1	SMAD specific E3 ubiquitin protein ligase 1	0.014
MST1R	macrophage stimulating 1 receptor (c-met-related tyrosine kinase)	0.013
RTKN	rhotekin	0.012
GGA3	golgi-associated, gamma adaptin ear containing, ARF binding protein 3	0.010