|
|
negative regulation of transcription from rna polymerase ii promoter
|
GO:0000122 |
281 |
1.000
|
Mouse |
|
|
collateral sprouting
|
GO:0048668 |
2 |
0.999
|
Fly |
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.983
|
Zebrafish Fly |
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
125 |
0.977
|
Human |
|
|
response to reactive oxygen species
|
GO:0000302 |
61 |
0.971
|
Human |
|
|
positive regulation of transcription from rna polymerase ii promoter in response to stress
|
GO:0036003 |
9 |
0.962
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.962
|
|
|
|
negative regulation of humoral immune response
|
GO:0002921 |
7 |
0.961
|
|
|
|
cellular response to transforming growth factor beta stimulus
|
GO:0071560 |
94 |
0.946
|
Human |
|
|
neuron projection regeneration
|
GO:0031102 |
1 |
0.934
|
Fly |
|
|
myeloid cell differentiation
|
GO:0030099 |
117 |
0.933
|
|
|
|
negative regulation of cell differentiation
|
GO:0045596 |
171 |
0.924
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.916
|
Fly |
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.909
|
Human |
|
|
regulation of transcription from rna polymerase ii promoter in response to stress
|
GO:0043618 |
17 |
0.900
|
|
|
|
response to camp
|
GO:0051591 |
25 |
0.879
|
|
|
|
erythrocyte differentiation
|
GO:0030218 |
28 |
0.876
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.873
|
|
|
|
transforming growth factor beta receptor signaling pathway
|
GO:0007179 |
76 |
0.850
|
Human |
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.836
|
Human |
|
|
negative regulation of transcription from rna polymerase ii promoter in response to endoplasmic reticulum stress
|
GO:1990441 |
1 |
0.833
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.831
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.810
|
Fly |
|
|
locomotory behavior
|
GO:0007626 |
1 |
0.802
|
Fly |
|
|
response to organophosphorus
|
GO:0046683 |
41 |
0.797
|
|
|
|
intra s dna damage checkpoint
|
GO:0031573 |
4 |
0.777
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.764
|
Human |
|
|
osteoblast differentiation
|
GO:0001649 |
92 |
0.762
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.756
|
|
|
|
covalent chromatin modification
|
GO:0016569 |
254 |
0.755
|
|
|
|
regeneration
|
GO:0031099 |
4 |
0.746
|
Fly |
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.734
|
|
|
|
mitotic cell cycle phase transition
|
GO:0044772 |
162 |
0.734
|
Fly |
|
|
blood vessel development
|
GO:0001568 |
172 |
0.730
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.724
|
|
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
131 |
0.721
|
|
|
|
response to endoplasmic reticulum stress
|
GO:0034976 |
49 |
0.716
|
|
|
|
response to calcium ion
|
GO:0051592 |
46 |
0.716
|
|
|
|
humoral immune response
|
GO:0006959 |
49 |
0.708
|
Fly |
|
|
response to inorganic substance
|
GO:0010035 |
127 |
0.682
|
|
|
|
circadian behavior
|
GO:0048512 |
2 |
0.678
|
Fly |
|
|
microglial cell activation
|
GO:0001774 |
2 |
0.657
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.638
|
Human |
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.630
|
Fly |
|
|
endoplasmic reticulum unfolded protein response
|
GO:0030968 |
16 |
0.630
|
|
|
|
response to growth factor
|
GO:0070848 |
205 |
0.628
|
Human |
|
|
negative regulation of viral transcription
|
GO:0032897 |
23 |
0.626
|
|
|
|
system process
|
GO:0003008 |
349 |
0.625
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.621
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.612
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.609
|
Fly |
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.608
|
|
|
|
positive regulation of viral transcription
|
GO:0050434 |
13 |
0.598
|
|
|
|
response to mechanical stimulus
|
GO:0009612 |
51 |
0.592
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.586
|
|
|
|
response to hydrogen peroxide
|
GO:0042542 |
40 |
0.586
|
|
|
|
mapk cascade
|
GO:0000165 |
288 |
0.579
|
|
|
|
cardiovascular system development
|
GO:0072358 |
262 |
0.575
|
|
|
|
wound healing
|
GO:0042060 |
115 |
0.573
|
Fly |
|
|
regulation of osteoblast differentiation
|
GO:0045667 |
38 |
0.566
|
|
|
|
positive regulation of osteoblast differentiation
|
GO:0045669 |
23 |
0.561
|
|
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.557
|
|
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.550
|
|
|
|
cellular response to oxidative stress
|
GO:0034599 |
85 |
0.546
|
Human |
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.541
|
|
|
|
cellular response to reactive oxygen species
|
GO:0034614 |
50 |
0.540
|
Human |
|
|
developmental cell growth
|
GO:0048588 |
18 |
0.523
|
Fly |
|
|
regulation of cytokine production
|
GO:0001817 |
232 |
0.523
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
380 |
0.521
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
156 |
0.501
|
|
|
|
regulation of ossification
|
GO:0030278 |
58 |
0.491
|
|
|
|
response to external biotic stimulus
|
GO:0043207 |
261 |
0.490
|
Zebrafish Fly |
|
|
interspecies interaction between organisms
|
GO:0044419 |
156 |
0.489
|
|
|
|
developmental growth involved in morphogenesis
|
GO:0060560 |
23 |
0.487
|
Fly |
|
|
muscle structure development
|
GO:0061061 |
98 |
0.486
|
Mouse |
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
211 |
0.485
|
|
|
|
associative learning
|
GO:0008306 |
1 |
0.483
|
|
|
|
response to transforming growth factor beta
|
GO:0071559 |
94 |
0.476
|
Human |
|
|
muscle organ development
|
GO:0007517 |
56 |
0.475
|
Mouse |
|
|
regulation of cyclin dependent protein serine threonine kinase activity
|
GO:0000079 |
36 |
0.474
|
Fly |
|
|
embryo development
|
GO:0009790 |
123 |
0.473
|
Fly |
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.466
|
|
|
|
regulation of rho protein signal transduction
|
GO:0035023 |
79 |
0.464
|
|
|
|
antimicrobial humoral response
|
GO:0019730 |
26 |
0.455
|
Fly |
|
|
membrane organization
|
GO:0061024 |
292 |
0.452
|
|
|
|
negative regulation of transcription from rna polymerase ii promoter in response to stress
|
GO:0097201 |
5 |
0.449
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
136 |
0.443
|
|
|
|
muscle tissue development
|
GO:0060537 |
62 |
0.439
|
Mouse |
|
|
response to other organism
|
GO:0051707 |
261 |
0.430
|
Zebrafish Fly |
|
|
response to radiation
|
GO:0009314 |
151 |
0.424
|
|
|
|
regulation of mitochondrial membrane permeability
|
GO:0046902 |
25 |
0.421
|
|
|
|
regulation of dna templated transcription in response to stress
|
GO:0043620 |
18 |
0.420
|
|
|
|
response to nitrosative stress
|
GO:0051409 |
4 |
0.412
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.411
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.410
|
|
|
|
histone acetylation
|
GO:0016573 |
93 |
0.403
|
|
|
|
smad protein signal transduction
|
GO:0060395 |
10 |
0.400
|
Human |
|
|
positive regulation of rho gtpase activity
|
GO:0032321 |
56 |
0.399
|
|
|
|
mitochondrial membrane organization
|
GO:0007006 |
40 |
0.395
|
|
|
|
rhythmic behavior
|
GO:0007622 |
2 |
0.395
|
Fly |
|
|
regulation of rho gtpase activity
|
GO:0032319 |
66 |
0.393
|
|
|
|
response to nitrogen compound
|
GO:1901698 |
184 |
0.390
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.390
|
|
|
|
striated muscle tissue development
|
GO:0014706 |
59 |
0.389
|
Mouse |
|
|
viral gene expression
|
GO:0019080 |
35 |
0.370
|
|
|
|
modification by host of symbiont morphology or physiology
|
GO:0051851 |
26 |
0.370
|
|
|
|
cellular response to metal ion
|
GO:0071248 |
43 |
0.369
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
172 |
0.367
|
|
|
|
negative regulation of cell cycle process
|
GO:0010948 |
121 |
0.366
|
|
|
|
regulation of multi organism process
|
GO:0043900 |
157 |
0.359
|
|
|
|
symbiosis encompassing mutualism through parasitism
|
GO:0044403 |
156 |
0.358
|
|
|
|
erythrocyte homeostasis
|
GO:0034101 |
31 |
0.349
|
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.346
|
|
|
|
response to light stimulus
|
GO:0009416 |
87 |
0.346
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.343
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
162 |
0.342
|
|
|
|
response to metal ion
|
GO:0010038 |
84 |
0.340
|
|
|
|
hemopoiesis
|
GO:0030097 |
180 |
0.333
|
|
|
|
heart process
|
GO:0003015 |
62 |
0.333
|
|
|
|
protein targeting to nucleus
|
GO:0044744 |
104 |
0.324
|
|
|
|
protein import into nucleus
|
GO:0006606 |
104 |
0.317
|
|
|
|
cell cycle phase transition
|
GO:0044770 |
173 |
0.316
|
Fly |
|
|
response to cytokine
|
GO:0034097 |
232 |
0.312
|
|
|
|
negative regulation of sequence specific dna binding transcription factor activity
|
GO:0043433 |
89 |
0.306
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.303
|
|
|
|
skeletal muscle cell differentiation
|
GO:0035914 |
6 |
0.294
|
Mouse |
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.293
|
|
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.289
|
Human |
|
|
dna replication
|
GO:0006260 |
116 |
0.289
|
|
|
|
circulatory system development
|
GO:0072359 |
262 |
0.287
|
|
|
|
response to axon injury
|
GO:0048678 |
1 |
0.285
|
Fly |
|
|
ossification
|
GO:0001503 |
121 |
0.285
|
|
|
|
cation transport
|
GO:0006812 |
331 |
0.283
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.281
|
Fly |
|
|
regulation of binding
|
GO:0051098 |
111 |
0.281
|
|
|
|
regulation of viral transcription
|
GO:0046782 |
34 |
0.280
|
|
|
|
regulation of determination of dorsal identity
|
GO:2000015 |
2 |
0.279
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.277
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.276
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
135 |
0.275
|
Fly |
|
|
determination of dorsal ventral asymmetry
|
GO:0048262 |
4 |
0.266
|
|
|
|
histone modification
|
GO:0016570 |
251 |
0.261
|
|
|
|
growth
|
GO:0040007 |
202 |
0.259
|
Fly |
|
|
positive regulation of neuron apoptotic process
|
GO:0043525 |
8 |
0.258
|
|
|
|
cell activation
|
GO:0001775 |
213 |
0.258
|
|
|
|
modulation by host of symbiont transcription
|
GO:0052472 |
20 |
0.257
|
|
|
|
regulation of myotube differentiation
|
GO:0010830 |
18 |
0.256
|
|
|
|
endothelial cell migration
|
GO:0043542 |
86 |
0.255
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.249
|
Fly |
|
|
peptidyl lysine acetylation
|
GO:0018394 |
101 |
0.248
|
|
|
|
negative regulation of binding
|
GO:0051100 |
57 |
0.248
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
63 |
0.246
|
|
|
|
chromatin modification
|
GO:0016568 |
298 |
0.245
|
|
|
|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
156 |
0.245
|
|
|
|
cellular response to calcium ion
|
GO:0071277 |
19 |
0.244
|
|
|
|
negative regulation by host of viral transcription
|
GO:0043922 |
12 |
0.239
|
|
|
|
immune response
|
GO:0006955 |
307 |
0.237
|
Fly |
|
|
negative regulation of immune system process
|
GO:0002683 |
136 |
0.231
|
|
|
|
mitochondrial transport
|
GO:0006839 |
60 |
0.229
|
|
|
|
regulation of viral process
|
GO:0050792 |
103 |
0.228
|
|
|
|
axon regeneration
|
GO:0031103 |
1 |
0.227
|
Fly |
|
|
regulation of homeostatic process
|
GO:0032844 |
121 |
0.226
|
|
|
|
negative regulation of myoblast differentiation
|
GO:0045662 |
7 |
0.225
|
|
|
|
negative regulation of kinase activity
|
GO:0033673 |
106 |
0.225
|
|
|
|
apoptotic mitochondrial changes
|
GO:0008637 |
57 |
0.224
|
|
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.222
|
|
|
|
regulation of antimicrobial humoral response
|
GO:0002759 |
1 |
0.220
|
|
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.219
|
|
|
|
heart contraction
|
GO:0060047 |
62 |
0.218
|
|
|
|
response to wounding
|
GO:0009611 |
168 |
0.218
|
Fly |
|
|
response to topologically incorrect protein
|
GO:0035966 |
29 |
0.215
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.212
|
Fly |
|
|
cellular response to topologically incorrect protein
|
GO:0035967 |
19 |
0.211
|
|
|
|
mitochondrial outer membrane permeabilization involved in programmed cell death
|
GO:1902686 |
16 |
0.210
|
|
|
|
positive regulation by host of viral transcription
|
GO:0043923 |
11 |
0.208
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.207
|
|
|
|
single organism membrane organization
|
GO:0044802 |
268 |
0.205
|
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
209 |
0.204
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.200
|
|
|
|
regulation of muscle cell differentiation
|
GO:0051147 |
31 |
0.198
|
|
|
|
mitotic cell cycle checkpoint
|
GO:0007093 |
68 |
0.197
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.196
|
|
|
|
regulation of myeloid cell differentiation
|
GO:0045637 |
81 |
0.196
|
|
|
|
immune system development
|
GO:0002520 |
195 |
0.196
|
|
|
|
cell migration involved in sprouting angiogenesis
|
GO:0002042 |
19 |
0.194
|
|
|
|
negative regulation of erythrocyte differentiation
|
GO:0045647 |
3 |
0.194
|
|
|
|
negative regulation of creb transcription factor activity
|
GO:0032792 |
1 |
0.190
|
|
|
|
cellular response to hydrogen peroxide
|
GO:0070301 |
37 |
0.185
|
|
|
|
sleep
|
GO:0030431 |
2 |
0.184
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.181
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
75 |
0.180
|
|
|
|
modulation by host of viral transcription
|
GO:0043921 |
20 |
0.180
|
|
|
|
jnk cascade
|
GO:0007254 |
80 |
0.179
|
|
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
185 |
0.178
|
|
|
|
cell cycle g2 m phase transition
|
GO:0044839 |
43 |
0.176
|
Fly |
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
206 |
0.173
|
|
|
|
cellular response to external stimulus
|
GO:0071496 |
111 |
0.172
|
|
|
|
positive regulation of mitochondrial membrane permeability involved in apoptotic process
|
GO:1902110 |
16 |
0.170
|
|
|
|
cellular response to biotic stimulus
|
GO:0071216 |
71 |
0.170
|
|
|
|
blood vessel maturation
|
GO:0001955 |
1 |
0.170
|
|
|
|
digestive system development
|
GO:0055123 |
75 |
0.169
|
|
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
186 |
0.166
|
|
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.165
|
|
|
|
generation of neurons
|
GO:0048699 |
152 |
0.165
|
Fly |
|
|
rhythmic process
|
GO:0048511 |
31 |
0.164
|
Fly |
|
|
positive regulation of mitochondrial membrane permeability
|
GO:0035794 |
17 |
0.163
|
|
|
|
proteasomal protein catabolic process
|
GO:0010498 |
176 |
0.162
|
|
|
|
regulation of canonical wnt signaling pathway
|
GO:0060828 |
88 |
0.160
|
|
|
|
regulation of membrane permeability
|
GO:0090559 |
25 |
0.159
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
125 |
0.158
|
|
|
|
nuclear transport
|
GO:0051169 |
179 |
0.158
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.157
|
|
|
|
muscle cell development
|
GO:0055001 |
29 |
0.156
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.155
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.155
|
|
|
|
chromatin organization
|
GO:0006325 |
351 |
0.154
|
|
|
|
positive regulation of blood circulation
|
GO:1903524 |
12 |
0.153
|
|
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
212 |
0.153
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.149
|
Fly |
|
|
cellular protein catabolic process
|
GO:0044257 |
261 |
0.149
|
|
|
|
compound eye development
|
GO:0048749 |
1 |
0.148
|
Fly |
|
|
regulation of dna metabolic process
|
GO:0051052 |
153 |
0.148
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.147
|
|
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.143
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
408 |
0.142
|
|
|
|
circulatory system process
|
GO:0003013 |
113 |
0.139
|
|
|
|
skin development
|
GO:0043588 |
76 |
0.138
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.138
|
|
|
|
neuron development
|
GO:0048666 |
113 |
0.137
|
Fly |
|
|
g2 m transition of mitotic cell cycle
|
GO:0000086 |
41 |
0.133
|
Fly |
|
|
negative regulation of mitotic cell cycle phase transition
|
GO:1901991 |
85 |
0.133
|
|
|
|
myoblast differentiation
|
GO:0045445 |
21 |
0.130
|
|
|
|
modification of morphology or physiology of other organism
|
GO:0035821 |
43 |
0.130
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
193 |
0.129
|
|
|
|
multi organism metabolic process
|
GO:0044033 |
41 |
0.126
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.126
|
|
|
|
response to bacterium
|
GO:0009617 |
144 |
0.124
|
|
|
|
response to unfolded protein
|
GO:0006986 |
24 |
0.124
|
|
|
|
response to lipopolysaccharide
|
GO:0032496 |
70 |
0.124
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.124
|
Fly |
|
|
nucleocytoplasmic transport
|
GO:0006913 |
176 |
0.120
|
|
|
|
viral process
|
GO:0016032 |
146 |
0.118
|
|
|
|
osteoblast development
|
GO:0002076 |
2 |
0.118
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
244 |
0.118
|
|
|
|
regulation of myoblast differentiation
|
GO:0045661 |
12 |
0.117
|
|
|
|
multi organism cellular process
|
GO:0044764 |
156 |
0.117
|
|
|
|
regulation of striated muscle cell differentiation
|
GO:0051153 |
25 |
0.117
|
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
167 |
0.116
|
|
|
|
cellular response to inorganic substance
|
GO:0071241 |
45 |
0.113
|
|
|
|
response to temperature stimulus
|
GO:0009266 |
22 |
0.113
|
|
|
|
negative regulation of viral process
|
GO:0048525 |
66 |
0.112
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.109
|
|
|
|
regulation of neuron death
|
GO:1901214 |
56 |
0.109
|
|
|
|
nuclear import
|
GO:0051170 |
106 |
0.109
|
|
|
|
melanin metabolic process
|
GO:0006582 |
1 |
0.109
|
|
|
|
regulation of response to biotic stimulus
|
GO:0002831 |
55 |
0.108
|
|
|
|
ectoderm development
|
GO:0007398 |
3 |
0.108
|
|
|
|
protein deacylation
|
GO:0035601 |
39 |
0.107
|
|
|
|
single organism nuclear import
|
GO:1902593 |
104 |
0.107
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.105
|
|
|
|
regulation of translation
|
GO:0006417 |
89 |
0.105
|
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
127 |
0.104
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.101
|
|
|
|
response to purine containing compound
|
GO:0014074 |
40 |
0.101
|
|
|
|
modification of morphology or physiology of other organism involved in symbiotic interaction
|
GO:0051817 |
38 |
0.101
|
|
|
|
regulation of immune response
|
GO:0050776 |
201 |
0.101
|
|
|
|
regulation of angiogenesis
|
GO:0045765 |
92 |
0.099
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.097
|
|
|
|
regulation of interleukin 8 production
|
GO:0032677 |
49 |
0.096
|
|
|
|
cation homeostasis
|
GO:0055080 |
189 |
0.096
|
|
|
|
response to oxidative stress
|
GO:0006979 |
121 |
0.095
|
Human |
|
|
blood vessel endothelial cell migration
|
GO:0043534 |
42 |
0.095
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
189 |
0.092
|
|
|
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
185 |
0.092
|
|
|
|
defense response to other organism
|
GO:0098542 |
129 |
0.091
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
391 |
0.091
|
|
|
|
gtp catabolic process
|
GO:0006184 |
237 |
0.091
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
181 |
0.091
|
|
|
|
canonical wnt signaling pathway
|
GO:0060070 |
116 |
0.090
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
264 |
0.090
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.090
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.090
|
|
|
|
osteoclast differentiation
|
GO:0030316 |
21 |
0.089
|
|
|
|
positive regulation of cellular protein catabolic process
|
GO:1903364 |
37 |
0.089
|
|
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.089
|
|
|
|
vasculature development
|
GO:0001944 |
181 |
0.089
|
|
|
|
response to lipid
|
GO:0033993 |
206 |
0.088
|
|
|
|
endocytosis
|
GO:0006897 |
159 |
0.087
|
|
|
|
viral transcription
|
GO:0019083 |
35 |
0.087
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.087
|
|
|
|
endothelial cell proliferation
|
GO:0001935 |
65 |
0.087
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
227 |
0.085
|
|
|
|
regulation of dna binding
|
GO:0051101 |
37 |
0.085
|
|
|
|
negative regulation of jun kinase activity
|
GO:0043508 |
4 |
0.084
|
|
|
|
peptidyl lysine modification
|
GO:0018205 |
144 |
0.084
|
|
|
|
negative regulation of angiogenesis
|
GO:0016525 |
39 |
0.083
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
404 |
0.083
|
|
|
|
calcium ion transport
|
GO:0006816 |
147 |
0.083
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
394 |
0.083
|
|
|
|
embryonic organ development
|
GO:0048568 |
36 |
0.081
|
|
|
|
determination of dorsal identity
|
GO:0048263 |
4 |
0.081
|
|
|
|
positive regulation of multi organism process
|
GO:0043902 |
56 |
0.080
|
|
|
|
regulation of muscle organ development
|
GO:0048634 |
27 |
0.080
|
|
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.080
|
|
|
|
neuron death
|
GO:0070997 |
65 |
0.080
|
|
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
4 |
0.079
|
Fly |
|
|
response to glucocorticoid
|
GO:0051384 |
13 |
0.079
|
|
|
|
response to molecule of bacterial origin
|
GO:0002237 |
82 |
0.078
|
|
|
|
modulation of transcription in other organism involved in symbiotic interaction
|
GO:0052312 |
20 |
0.078
|
|
|
|
regulation of system process
|
GO:0044057 |
101 |
0.077
|
|
|
|
positive regulation of immune response
|
GO:0050778 |
159 |
0.077
|
|
|
|
cellular homeostasis
|
GO:0019725 |
196 |
0.077
|
|
|
|
positive regulation of myeloid cell differentiation
|
GO:0045639 |
39 |
0.076
|
|
|
|
response to hormone
|
GO:0009725 |
175 |
0.076
|
|
|
|
positive regulation of viral process
|
GO:0048524 |
37 |
0.076
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
398 |
0.076
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
405 |
0.075
|
|
|
|
regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903050 |
91 |
0.073
|
|
|
|
interaction with symbiont
|
GO:0051702 |
26 |
0.073
|
|
|
|
positive regulation of histone modification
|
GO:0031058 |
29 |
0.072
|
|
|
|
regulation of glomerular mesangial cell proliferation
|
GO:0072124 |
3 |
0.071
|
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
125 |
0.071
|
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.070
|
Fly |
|
|
response to organic cyclic compound
|
GO:0014070 |
204 |
0.070
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
392 |
0.069
|
|
|
|
trophectodermal cell differentiation
|
GO:0001829 |
3 |
0.069
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
408 |
0.069
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.069
|
|
|
|
neurological system process
|
GO:0050877 |
163 |
0.068
|
|
|
|
skeletal muscle tissue development
|
GO:0007519 |
24 |
0.068
|
Mouse |
|
|
skeletal muscle fiber development
|
GO:0048741 |
12 |
0.067
|
|
|
|
anterior posterior pattern specification
|
GO:0009952 |
9 |
0.067
|
|
|
|
regulation of small gtpase mediated signal transduction
|
GO:0051056 |
156 |
0.067
|
|
|
|
sensory organ development
|
GO:0007423 |
52 |
0.067
|
Fly |
|
|
regulation of endopeptidase activity
|
GO:0052548 |
170 |
0.066
|
|
|
|
positive regulation of neuron death
|
GO:1901216 |
14 |
0.065
|
|
|
|
chemokine c x c motif ligand 2 production
|
GO:0072567 |
3 |
0.065
|
|
|
|
protein import
|
GO:0017038 |
130 |
0.065
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
239 |
0.065
|
|
|
|
neuromuscular junction development
|
GO:0007528 |
3 |
0.064
|
Fly |
|
|
cell growth
|
GO:0016049 |
160 |
0.064
|
Fly |
|
|
regulation of symbiosis encompassing mutualism through parasitism
|
GO:0043903 |
109 |
0.064
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.063
|
|
|
|
positive regulation of leukocyte differentiation
|
GO:1902107 |
37 |
0.063
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
3 |
0.062
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.062
|
|
|
|
homeostasis of number of cells
|
GO:0048872 |
40 |
0.062
|
|
|
|
post embryonic hemopoiesis
|
GO:0035166 |
1 |
0.061
|
|
|
|
cranial nerve morphogenesis
|
GO:0021602 |
1 |
0.060
|
|
|
|
hyperosmotic response
|
GO:0006972 |
4 |
0.060
|
|
|
|
cytokine production
|
GO:0001816 |
247 |
0.060
|
|
|
|
anterior posterior axis specification
|
GO:0009948 |
2 |
0.060
|
|
|
|
positive regulation of immune system process
|
GO:0002684 |
283 |
0.060
|
|
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
60 |
0.060
|
|
|
|
circadian rhythm
|
GO:0007623 |
21 |
0.060
|
Fly |
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
412 |
0.059
|
|
|
|
skeletal muscle organ development
|
GO:0060538 |
26 |
0.059
|
Mouse |
|
|
mitochondrion organization
|
GO:0007005 |
156 |
0.059
|
|
|
|
positive regulation of ras gtpase activity
|
GO:0032320 |
117 |
0.059
|
|
|
|
foam cell differentiation
|
GO:0090077 |
15 |
0.058
|
|
|
|
regulation of ras gtpase activity
|
GO:0032318 |
128 |
0.057
|
|
|
|
positive regulation of reactive oxygen species metabolic process
|
GO:2000379 |
24 |
0.057
|
|
|
|
internal protein amino acid acetylation
|
GO:0006475 |
101 |
0.057
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
26 |
0.057
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.057
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.057
|
Fly |
|
|
mitotic dna integrity checkpoint
|
GO:0044774 |
30 |
0.057
|
|
|
|
maintenance of location
|
GO:0051235 |
112 |
0.056
|
|
|
|
cellular response to unfolded protein
|
GO:0034620 |
16 |
0.055
|
|
|
|
protein acylation
|
GO:0043543 |
138 |
0.055
|
|
|
|
viral life cycle
|
GO:0019058 |
132 |
0.055
|
|
|
|
sequestering of calcium ion
|
GO:0051208 |
17 |
0.055
|
|
|
|
response to drug
|
GO:0042493 |
81 |
0.055
|
|
|
|
regulation of mitochondrial membrane permeability involved in apoptotic process
|
GO:1902108 |
18 |
0.054
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
209 |
0.053
|
|
|
|
negative regulation of protein serine threonine kinase activity
|
GO:0071901 |
57 |
0.053
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
207 |
0.053
|
Mouse |
|
|
calcium ion transport into cytosol
|
GO:0060402 |
48 |
0.053
|
|
|
|
cellular cation homeostasis
|
GO:0030003 |
163 |
0.053
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.052
|
Fly |
|
|
regulation of protein binding
|
GO:0043393 |
66 |
0.051
|
|
|
|
negative regulation of mitotic cell cycle
|
GO:0045930 |
102 |
0.051
|
|
|
|
regulation of defense response
|
GO:0031347 |
154 |
0.050
|
|
|
|
regulation of neuron apoptotic process
|
GO:0043523 |
35 |
0.050
|
|
|
|
behavior
|
GO:0007610 |
112 |
0.050
|
Fly |
|
|
regulation of mitotic cell cycle phase transition
|
GO:1901990 |
118 |
0.050
|
|
|
|
striated muscle cell differentiation
|
GO:0051146 |
43 |
0.050
|
|
|
|
reactive oxygen species biosynthetic process
|
GO:1903409 |
4 |
0.050
|
|
|
|
sequestering of metal ion
|
GO:0051238 |
24 |
0.049
|
|
|
|
muscle fiber development
|
GO:0048747 |
16 |
0.049
|
|
|
|
regulation of dna replication
|
GO:0006275 |
68 |
0.049
|
|
|
|
negative regulation of wnt signaling pathway
|
GO:0030178 |
69 |
0.049
|
|
|
|
regulation of neuronal synaptic plasticity
|
GO:0048168 |
1 |
0.049
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.048
|
|
|
|
developmental growth
|
GO:0048589 |
48 |
0.048
|
Fly |
|
|
positive regulation of heart contraction
|
GO:0045823 |
5 |
0.048
|
|
|
|
regulation of dna repair
|
GO:0006282 |
47 |
0.048
|
|
|
|
smad protein import into nucleus
|
GO:0007184 |
13 |
0.048
|
|
|
|
mrna transcription from rna polymerase ii promoter
|
GO:0042789 |
6 |
0.048
|
|
|
|
cell projection organization
|
GO:0030030 |
252 |
0.048
|
Fly |
|
|
negative regulation of response to external stimulus
|
GO:0032102 |
83 |
0.047
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.047
|
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
97 |
0.047
|
|
|
|
tissue migration
|
GO:0090130 |
119 |
0.047
|
Fly |
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
175 |
0.047
|
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
146 |
0.047
|
|
|
|
hemoglobin metabolic process
|
GO:0020027 |
3 |
0.046
|
|
|
|
negative regulation of sequestering of calcium ion
|
GO:0051283 |
41 |
0.046
|
|
|
|
immune effector process
|
GO:0002252 |
159 |
0.046
|
|
|
|
epithelium migration
|
GO:0090132 |
119 |
0.046
|
Fly |
|
|
negative regulation of homeostatic process
|
GO:0032845 |
59 |
0.046
|
|
|
|
protein autophosphorylation
|
GO:0046777 |
123 |
0.046
|
|
|
|
response to osmotic stress
|
GO:0006970 |
17 |
0.046
|
|
|
|
nuclear division
|
GO:0000280 |
128 |
0.045
|
|
|
|
protein targeting
|
GO:0006605 |
187 |
0.045
|
|
|
|
innate immune response
|
GO:0045087 |
178 |
0.044
|
|
|
|
response to ketone
|
GO:1901654 |
19 |
0.044
|
|
|
|
oocyte differentiation
|
GO:0009994 |
2 |
0.044
|
|
|
|
negative regulation of erk1 and erk2 cascade
|
GO:0070373 |
14 |
0.044
|
|
|
|
regulation of muscle tissue development
|
GO:1901861 |
26 |
0.044
|
|
|
|
protein deacetylation
|
GO:0006476 |
38 |
0.043
|
|
|
|
positive regulation of endothelial cell proliferation
|
GO:0001938 |
37 |
0.043
|
|
|
|
positive regulation of hemoglobin biosynthetic process
|
GO:0046985 |
1 |
0.043
|
|
|
|
negative regulation of chemokine production
|
GO:0032682 |
9 |
0.043
|
|
|
|
negative regulation of muscle cell differentiation
|
GO:0051148 |
17 |
0.043
|
|
|
|
regulation of protein processing
|
GO:0070613 |
150 |
0.043
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
205 |
0.043
|
|
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
117 |
0.043
|
|
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.042
|
|
|
|
positive regulation of osteoclast differentiation
|
GO:0045672 |
9 |
0.042
|
|
|
|
protein acetylation
|
GO:0006473 |
116 |
0.042
|
|
|
|
regulation of chromosome organization
|
GO:0033044 |
103 |
0.042
|
|
|
|
digestive tract morphogenesis
|
GO:0048546 |
56 |
0.041
|
|
|
|
chordate embryonic development
|
GO:0043009 |
34 |
0.041
|
|
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
136 |
0.041
|
|
|
|
translation
|
GO:0006412 |
132 |
0.041
|
|
|
|
striated muscle cell development
|
GO:0055002 |
27 |
0.041
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
181 |
0.041
|
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
94 |
0.041
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
98 |
0.041
|
|
|
|
blood circulation
|
GO:0008015 |
113 |
0.040
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.040
|
|
|
|
positive regulation of interleukin 8 production
|
GO:0032757 |
36 |
0.040
|
|
|
|
negative regulation of proteolysis
|
GO:0045861 |
132 |
0.040
|
|
|
|
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
|
GO:0070059 |
12 |
0.040
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.040
|
|
|
|
cytokine biosynthetic process
|
GO:0042089 |
37 |
0.040
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
342 |
0.040
|
|
|
|
regulation of histone modification
|
GO:0031056 |
47 |
0.039
|
|
|
|
positive regulation of dna metabolic process
|
GO:0051054 |
73 |
0.039
|
|
|
|
learning
|
GO:0007612 |
11 |
0.039
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
195 |
0.039
|
|
|
|
defense response
|
GO:0006952 |
315 |
0.038
|
|
|
|
negative regulation of immune response
|
GO:0050777 |
40 |
0.038
|
|
|
|
cell part morphogenesis
|
GO:0032990 |
137 |
0.038
|
Fly |
|
|
leukocyte activation
|
GO:0045321 |
164 |
0.037
|
|
|
|
memory
|
GO:0007613 |
3 |
0.037
|
|
|
|
glucose metabolic process
|
GO:0006006 |
45 |
0.037
|
Mouse |
|
|
response to ionizing radiation
|
GO:0010212 |
65 |
0.037
|
|
|
|
regulation of skeletal muscle fiber development
|
GO:0048742 |
12 |
0.037
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.036
|
|
|
|
heart development
|
GO:0007507 |
95 |
0.036
|
|
|
|
brain morphogenesis
|
GO:0048854 |
1 |
0.036
|
|
|
|
hepaticobiliary system development
|
GO:0061008 |
10 |
0.036
|
|
|
|
response to corticosteroid
|
GO:0031960 |
15 |
0.036
|
|
|
|
negative regulation of cell cycle phase transition
|
GO:1901988 |
89 |
0.036
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
180 |
0.035
|
|
|
|
positive regulation of myeloid leukocyte differentiation
|
GO:0002763 |
24 |
0.035
|
|
|
|
response to testosterone
|
GO:0033574 |
1 |
0.035
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
113 |
0.035
|
|
|
|
regulation of proteasomal ubiquitin dependent protein catabolic process
|
GO:0032434 |
71 |
0.035
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
180 |
0.035
|
|
|
|
protein maturation
|
GO:0051604 |
233 |
0.035
|
|
|
|
regulation of gtpase activity
|
GO:0043087 |
180 |
0.035
|
|
|
|
regulation of response to dna damage stimulus
|
GO:2001020 |
94 |
0.035
|
|
|
|
regulation of cell development
|
GO:0060284 |
161 |
0.034
|
|
|
|
regulation of response to external stimulus
|
GO:0032101 |
222 |
0.034
|
|
|
|
negative regulation of multi organism process
|
GO:0043901 |
92 |
0.034
|
|
|
|
interleukin 8 production
|
GO:0032637 |
51 |
0.033
|
|
|
|
negative regulation of transferase activity
|
GO:0051348 |
124 |
0.033
|
|
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
61 |
0.033
|
|
|
|
regulation of stress activated protein kinase signaling cascade
|
GO:0070302 |
85 |
0.033
|
|
|
|
branch elongation of an epithelium
|
GO:0060602 |
3 |
0.033
|
|
|
|
myotube cell development
|
GO:0014904 |
14 |
0.032
|
|
|
|
macromolecule methylation
|
GO:0043414 |
97 |
0.032
|
|
|
|
negative regulation of protein maturation
|
GO:1903318 |
142 |
0.032
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.032
|
|
|
|
negative regulation of endopeptidase activity
|
GO:0010951 |
84 |
0.032
|
|
|
|
peptidyl tyrosine dephosphorylation
|
GO:0035335 |
36 |
0.032
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.032
|
|
|
|
head development
|
GO:0060322 |
108 |
0.031
|
|
|
|
limbic system development
|
GO:0021761 |
3 |
0.031
|
|
|
|
cytosolic calcium ion homeostasis
|
GO:0051480 |
89 |
0.031
|
|
|
|
myotube differentiation
|
GO:0014902 |
22 |
0.031
|
|
|
|
negative regulation of mapk cascade
|
GO:0043409 |
56 |
0.031
|
|
|
|
epithelium development
|
GO:0060429 |
227 |
0.031
|
Fly |
