|
|
positive regulation of pathway restricted smad protein phosphorylation
|
GO:0010862 |
22 |
1.000
|
|
|
|
negative regulation of trophoblast cell migration
|
GO:1901164 |
3 |
1.000
|
Human |
|
|
regulation of determination of dorsal identity
|
GO:2000015 |
2 |
1.000
|
Human |
|
|
negative regulation of chondrocyte proliferation
|
GO:1902731 |
1 |
0.999
|
|
|
|
regulation of pathway restricted smad protein phosphorylation
|
GO:0060393 |
34 |
0.999
|
|
|
|
determination of dorsal identity
|
GO:0048263 |
4 |
0.998
|
Human |
|
|
positive regulation of determination of dorsal identity
|
GO:2000017 |
1 |
0.998
|
Human |
|
|
mitral valve morphogenesis
|
GO:0003183 |
2 |
0.997
|
Human |
|
|
positive regulation of biomineral tissue development
|
GO:0070169 |
20 |
0.997
|
|
|
|
endocardial cushion cell differentiation
|
GO:0061443 |
1 |
0.995
|
Human |
|
|
cardiac muscle cell fate commitment
|
GO:0060923 |
4 |
0.995
|
Human |
|
|
positive regulation of osteoblast differentiation
|
GO:0045669 |
23 |
0.995
|
|
|
|
positive regulation of trophoblast cell migration
|
GO:1901165 |
2 |
0.994
|
Human |
|
|
chorionic trophoblast cell proliferation
|
GO:0097360 |
2 |
0.989
|
Human |
|
|
endocardial cushion development
|
GO:0003197 |
3 |
0.985
|
Human |
|
|
pathway restricted smad protein phosphorylation
|
GO:0060389 |
38 |
0.985
|
|
|
|
endocardial cell differentiation
|
GO:0060956 |
2 |
0.983
|
Human |
|
|
positive regulation of erythrocyte differentiation
|
GO:0045648 |
11 |
0.983
|
Human |
|
|
cardiac atrium development
|
GO:0003230 |
10 |
0.979
|
Human |
|
|
cardiac endothelial cell differentiation
|
GO:0003348 |
2 |
0.978
|
Human |
|
|
cardiac atrium morphogenesis
|
GO:0003209 |
7 |
0.976
|
Human |
|
|
regulation of ossification
|
GO:0030278 |
58 |
0.971
|
|
|
|
regulation of smad protein import into nucleus
|
GO:0060390 |
10 |
0.969
|
Human |
|
|
regulation of bone mineralization
|
GO:0030500 |
29 |
0.967
|
|
|
|
positive regulation of smad protein import into nucleus
|
GO:0060391 |
8 |
0.964
|
Human |
|
|
atrioventricular valve development
|
GO:0003171 |
3 |
0.961
|
Human |
|
|
muscle cell fate commitment
|
GO:0042693 |
4 |
0.960
|
Human |
|
|
mesendoderm development
|
GO:0048382 |
1 |
0.958
|
|
|
|
embryonic heart tube morphogenesis
|
GO:0003143 |
8 |
0.955
|
Human Zebrafish |
|
|
epithelial cell fate commitment
|
GO:0072148 |
3 |
0.947
|
Human |
|
|
negative regulation of cell adhesion
|
GO:0007162 |
64 |
0.943
|
Human |
|
|
activation of mapkk activity
|
GO:0000186 |
18 |
0.941
|
Human |
|
|
atrioventricular valve morphogenesis
|
GO:0003181 |
2 |
0.940
|
Human |
|
|
pattern specification involved in kidney development
|
GO:0061004 |
1 |
0.921
|
|
|
|
endothelial cell proliferation
|
GO:0001935 |
65 |
0.912
|
|
|
|
peptidyl threonine phosphorylation
|
GO:0018107 |
41 |
0.912
|
Human |
|
|
wound healing
|
GO:0042060 |
115 |
0.911
|
Human |
|
|
negative regulation of glomerulus development
|
GO:0090194 |
2 |
0.909
|
|
|
|
atrial septum morphogenesis
|
GO:0060413 |
5 |
0.909
|
Human |
|
|
cardiac chamber morphogenesis
|
GO:0003206 |
26 |
0.909
|
Human |
|
|
endocardial cushion cell fate commitment
|
GO:0061445 |
1 |
0.905
|
Human |
|
|
activin receptor signaling pathway
|
GO:0032924 |
24 |
0.902
|
Human |
|
|
response to disaccharide
|
GO:0034285 |
1 |
0.895
|
|
|
|
response to cholesterol
|
GO:0070723 |
11 |
0.887
|
Human |
|
|
regulation of blood vessel endothelial cell migration
|
GO:0043535 |
30 |
0.882
|
Human |
|
|
atrial septum primum morphogenesis
|
GO:0003289 |
1 |
0.878
|
Human |
|
|
negative regulation of epithelial cell migration
|
GO:0010633 |
38 |
0.877
|
Human |
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.875
|
|
|
|
septum primum development
|
GO:0003284 |
1 |
0.868
|
Human |
|
|
chondrocyte proliferation
|
GO:0035988 |
4 |
0.866
|
|
|
|
regulation of lung blood pressure
|
GO:0014916 |
1 |
0.858
|
|
|
|
digestive tract development
|
GO:0048565 |
75 |
0.854
|
Mouse |
|
|
negative regulation of blood pressure
|
GO:0045776 |
3 |
0.850
|
|
|
|
formation of primary germ layer
|
GO:0001704 |
42 |
0.849
|
Mouse |
|
|
regulation of cell adhesion
|
GO:0030155 |
166 |
0.847
|
Human |
|
|
neural crest cell development
|
GO:0014032 |
3 |
0.841
|
|
|
|
organ morphogenesis
|
GO:0009887 |
147 |
0.828
|
Human Zebrafish |
|
|
system process
|
GO:0003008 |
349 |
0.827
|
|
|
|
endothelial cell migration
|
GO:0043542 |
86 |
0.827
|
|
|
|
response to wounding
|
GO:0009611 |
168 |
0.824
|
Human |
|
|
regulation of activin receptor signaling pathway
|
GO:0032925 |
14 |
0.822
|
Human |
|
|
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090101 |
45 |
0.819
|
Human |
|
|
bone mineralization
|
GO:0030282 |
34 |
0.819
|
|
|
|
endocardium development
|
GO:0003157 |
2 |
0.818
|
Human |
|
|
digestive system development
|
GO:0055123 |
75 |
0.817
|
Mouse |
|
|
heart morphogenesis
|
GO:0003007 |
48 |
0.814
|
Human Zebrafish |
|
|
positive regulation of cell motility
|
GO:2000147 |
177 |
0.812
|
|
|
|
regulation of epithelial cell migration
|
GO:0010632 |
93 |
0.807
|
|
|
|
response to growth factor
|
GO:0070848 |
205 |
0.803
|
Human |
|
|
blood circulation
|
GO:0008015 |
113 |
0.797
|
|
|
|
cardiac septum morphogenesis
|
GO:0060411 |
9 |
0.791
|
Human |
|
|
negative regulation of chorionic trophoblast cell proliferation
|
GO:1901383 |
2 |
0.790
|
Human |
|
|
endocardial cell fate commitment
|
GO:0060957 |
1 |
0.784
|
Human |
|
|
regulation of endothelial cell proliferation
|
GO:0001936 |
56 |
0.776
|
|
|
|
cell adhesion
|
GO:0007155 |
325 |
0.775
|
Human |
|
|
osteoblast differentiation
|
GO:0001649 |
92 |
0.772
|
|
|
|
positive regulation of locomotion
|
GO:0040017 |
186 |
0.770
|
|
|
|
cardiac muscle tissue development
|
GO:0048738 |
39 |
0.770
|
Human |
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.768
|
|
|
|
renal system pattern specification
|
GO:0072048 |
1 |
0.761
|
|
|
|
smad protein import into nucleus
|
GO:0007184 |
13 |
0.761
|
Human |
|
|
positive regulation of epithelial cell proliferation
|
GO:0050679 |
65 |
0.755
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.752
|
Human Mouse |
|
|
regulation of muscle system process
|
GO:0090257 |
53 |
0.752
|
|
|
|
anatomical structure regression
|
GO:0060033 |
1 |
0.750
|
|
|
|
negative regulation of cell migration
|
GO:0030336 |
102 |
0.748
|
Human |
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
41 |
0.738
|
Human |
|
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
0.734
|
Human |
|
|
mesenchyme development
|
GO:0060485 |
59 |
0.731
|
Human |
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.728
|
Human Fly |
|
|
branching morphogenesis of an epithelial tube
|
GO:0048754 |
19 |
0.727
|
|
|
|
biological adhesion
|
GO:0022610 |
331 |
0.724
|
Human |
|
|
negative regulation of cell proliferation involved in kidney development
|
GO:1901723 |
2 |
0.721
|
|
|
|
negative regulation of systemic arterial blood pressure
|
GO:0003085 |
1 |
0.718
|
|
|
|
angiogenesis
|
GO:0001525 |
147 |
0.716
|
Human |
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.699
|
|
|
|
stem cell division
|
GO:0017145 |
2 |
0.698
|
|
|
|
tube development
|
GO:0035295 |
125 |
0.696
|
Human Zebrafish Mouse |
|
|
negative regulation of kidney development
|
GO:0090185 |
2 |
0.696
|
|
|
|
apoptotic nuclear changes
|
GO:0030262 |
13 |
0.695
|
Human |
|
|
activation of protein kinase activity
|
GO:0032147 |
90 |
0.694
|
Human |
|
|
circulatory system process
|
GO:0003013 |
113 |
0.694
|
|
|
|
memory
|
GO:0007613 |
3 |
0.693
|
|
|
|
regulation of aldosterone biosynthetic process
|
GO:0032347 |
6 |
0.686
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.682
|
Human |
|
|
regulation of chorionic trophoblast cell proliferation
|
GO:1901382 |
2 |
0.678
|
Human |
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.678
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.677
|
|
|
|
cell matrix adhesion
|
GO:0007160 |
85 |
0.677
|
Human |
|
|
atrial septum development
|
GO:0003283 |
8 |
0.673
|
Human |
|
|
long term memory
|
GO:0007616 |
2 |
0.671
|
|
|
|
bmp signaling pathway
|
GO:0030509 |
49 |
0.669
|
|
|
|
muscle system process
|
GO:0003012 |
81 |
0.667
|
|
|
|
generation of neurons
|
GO:0048699 |
152 |
0.665
|
Mouse |
|
|
regulation of focal adhesion assembly
|
GO:0051893 |
20 |
0.658
|
Human |
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.653
|
Human |
|
|
negative regulation of glucocorticoid biosynthetic process
|
GO:0031947 |
4 |
0.652
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
75 |
0.650
|
Human |
|
|
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090100 |
41 |
0.648
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.648
|
|
|
|
endodermal cell fate specification
|
GO:0001714 |
4 |
0.646
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.646
|
Human |
|
|
negative regulation of steroid hormone biosynthetic process
|
GO:0090032 |
4 |
0.640
|
|
|
|
regulation of erythrocyte differentiation
|
GO:0045646 |
17 |
0.636
|
Human |
|
|
regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090092 |
90 |
0.634
|
|
|
|
tube morphogenesis
|
GO:0035239 |
95 |
0.631
|
Human Zebrafish Mouse |
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
119 |
0.630
|
Human |
|
|
positive regulation of myeloid cell differentiation
|
GO:0045639 |
39 |
0.628
|
Human |
|
|
regulation of peptidase activity
|
GO:0052547 |
180 |
0.626
|
Human |
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.626
|
Human Mouse |
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.624
|
Human Mouse |
|
|
regulation of cell junction assembly
|
GO:1901888 |
29 |
0.622
|
Human |
|
|
patterning of blood vessels
|
GO:0001569 |
2 |
0.621
|
|
|
|
gastrulation
|
GO:0007369 |
51 |
0.621
|
Mouse |
|
|
cardiac cell fate commitment
|
GO:0060911 |
7 |
0.618
|
Human |
|
|
cellular response to transforming growth factor beta stimulus
|
GO:0071560 |
94 |
0.615
|
Human |
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.607
|
|
|
|
regulation of cell cell adhesion
|
GO:0022407 |
57 |
0.604
|
|
|
|
positive regulation of endothelial cell proliferation
|
GO:0001938 |
37 |
0.601
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.597
|
|
|
|
cellular response to external stimulus
|
GO:0071496 |
111 |
0.591
|
|
|
|
negative regulation of cellular component movement
|
GO:0051271 |
106 |
0.590
|
Human |
|
|
female gamete generation
|
GO:0007292 |
2 |
0.590
|
|
|
|
peptidyl serine modification
|
GO:0018209 |
106 |
0.584
|
Human |
|
|
protein ubiquitination
|
GO:0016567 |
314 |
0.580
|
Human |
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.580
|
Human |
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
125 |
0.578
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.576
|
|
|
|
epithelial cell migration
|
GO:0010631 |
119 |
0.576
|
|
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
85 |
0.569
|
Human |
|
|
muscle cell differentiation
|
GO:0042692 |
63 |
0.568
|
Human |
|
|
oogenesis
|
GO:0048477 |
2 |
0.561
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
158 |
0.554
|
Fly |
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.554
|
|
|
|
regulation of endothelial cell migration
|
GO:0010594 |
67 |
0.540
|
|
|
|
negative regulation of cell motility
|
GO:2000146 |
104 |
0.537
|
Human |
|
|
gtp metabolic process
|
GO:0046039 |
239 |
0.534
|
|
|
|
negative regulation of cell growth
|
GO:0030308 |
83 |
0.529
|
|
|
|
determination of bilateral symmetry
|
GO:0009855 |
15 |
0.525
|
Human Zebrafish |
|
|
cellular response to starvation
|
GO:0009267 |
58 |
0.525
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.519
|
Mouse Fly |
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
404 |
0.517
|
|
|
|
mapk cascade
|
GO:0000165 |
288 |
0.514
|
Human |
|
|
regulation of multi organism process
|
GO:0043900 |
157 |
0.511
|
Human |
|
|
peptidyl serine phosphorylation
|
GO:0018105 |
101 |
0.508
|
Human |
|
|
regulation of cysteine type endopeptidase activity
|
GO:2000116 |
127 |
0.508
|
Human |
|
|
response to nutrient levels
|
GO:0031667 |
81 |
0.506
|
|
|
|
nodal signaling pathway
|
GO:0038092 |
5 |
0.503
|
Human |
|
|
regulation of bmp signaling pathway
|
GO:0030510 |
27 |
0.501
|
|
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.501
|
Human |
|
|
negative regulation of endothelial cell migration
|
GO:0010596 |
29 |
0.496
|
Human |
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.496
|
Human |
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.495
|
|
|
|
vasculature development
|
GO:0001944 |
181 |
0.494
|
Human Mouse |
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.493
|
Human |
|
|
cortisol biosynthetic process
|
GO:0034651 |
8 |
0.493
|
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
180 |
0.493
|
|
|
|
regulation of heart contraction
|
GO:0008016 |
50 |
0.492
|
|
|
|
mesenchymal cell development
|
GO:0014031 |
50 |
0.491
|
Human |
|
|
limb morphogenesis
|
GO:0035108 |
16 |
0.491
|
Human |
|
|
segmentation
|
GO:0035282 |
4 |
0.490
|
|
|
|
neuron projection development
|
GO:0031175 |
106 |
0.489
|
Mouse |
|
|
bmp signaling pathway involved in heart development
|
GO:0061312 |
3 |
0.488
|
|
|
|
positive regulation of protein localization to nucleus
|
GO:1900182 |
48 |
0.487
|
Human |
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
175 |
0.486
|
Human |
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.485
|
Mouse |
|
|
regulation of homeostatic process
|
GO:0032844 |
121 |
0.485
|
Human |
|
|
regulation of cell substrate junction assembly
|
GO:0090109 |
20 |
0.482
|
Human |
|
|
defense response to fungus
|
GO:0050832 |
4 |
0.482
|
|
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.481
|
Human |
|
|
protein autophosphorylation
|
GO:0046777 |
123 |
0.479
|
Human |
|
|
regulation of blood pressure
|
GO:0008217 |
30 |
0.478
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
179 |
0.477
|
|
|
|
mesodermal cell fate specification
|
GO:0007501 |
2 |
0.477
|
|
|
|
lymphatic endothelial cell differentiation
|
GO:0060836 |
3 |
0.475
|
Human Mouse |
|
|
regulation of protein ubiquitination
|
GO:0031396 |
95 |
0.474
|
Human |
|
|
cardiac chamber development
|
GO:0003205 |
30 |
0.471
|
Human |
|
|
post embryonic development
|
GO:0009791 |
2 |
0.471
|
|
|
|
positive regulation of intracellular protein transport
|
GO:0090316 |
76 |
0.468
|
Human |
|
|
positive regulation of cysteine type endopeptidase activity
|
GO:2001056 |
79 |
0.458
|
Human |
|
|
morphogenesis of an epithelial sheet
|
GO:0002011 |
12 |
0.457
|
Human |
|
|
negative regulation of cell junction assembly
|
GO:1901889 |
5 |
0.457
|
Human |
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.455
|
Human |
|
|
ossification
|
GO:0001503 |
121 |
0.451
|
|
|
|
positive regulation of ossification
|
GO:0045778 |
32 |
0.451
|
|
|
|
cell cell junction organization
|
GO:0045216 |
69 |
0.450
|
Human |
|
|
regulation of nucleocytoplasmic transport
|
GO:0046822 |
98 |
0.441
|
Human |
|
|
negative regulation of bmp signaling pathway
|
GO:0030514 |
17 |
0.441
|
|
|
|
single organism nuclear import
|
GO:1902593 |
104 |
0.433
|
Human |
|
|
endodermal cell differentiation
|
GO:0035987 |
31 |
0.432
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.428
|
Human |
|
|
epithelial to mesenchymal transition
|
GO:0001837 |
48 |
0.425
|
Human |
|
|
growth
|
GO:0040007 |
202 |
0.423
|
|
|
|
negative regulation of blood vessel endothelial cell migration
|
GO:0043537 |
16 |
0.421
|
Human |
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
97 |
0.420
|
Human |
|
|
negative regulation of multi organism process
|
GO:0043901 |
92 |
0.419
|
Human |
|
|
ribonucleotide catabolic process
|
GO:0009261 |
405 |
0.417
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
117 |
0.411
|
Human |
|
|
response to fungus
|
GO:0009620 |
4 |
0.408
|
|
|
|
epithelial cell differentiation
|
GO:0030855 |
141 |
0.407
|
Human Mouse |
|
|
adherens junction organization
|
GO:0034332 |
36 |
0.405
|
Human |
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.400
|
Human |
|
|
regulation of systemic arterial blood pressure
|
GO:0003073 |
19 |
0.400
|
|
|
|
mitotic cell cycle phase transition
|
GO:0044772 |
162 |
0.396
|
Human |
|
|
response to extracellular stimulus
|
GO:0009991 |
85 |
0.396
|
|
|
|
positive regulation of cell growth
|
GO:0030307 |
48 |
0.391
|
Human Mouse |
|
|
response to nitric oxide
|
GO:0071731 |
4 |
0.390
|
|
|
|
negative regulation of extrinsic apoptotic signaling pathway
|
GO:2001237 |
52 |
0.388
|
Human |
|
|
regulation of cell substrate adhesion
|
GO:0010810 |
68 |
0.386
|
Human |
|
|
endodermal cell fate commitment
|
GO:0001711 |
4 |
0.386
|
|
|
|
defense response to other organism
|
GO:0098542 |
129 |
0.385
|
|
|
|
single organismal cell cell adhesion
|
GO:0016337 |
148 |
0.384
|
|
|
|
heart formation
|
GO:0060914 |
2 |
0.384
|
|
|
|
protein import into nucleus
|
GO:0006606 |
104 |
0.382
|
Human |
|
|
negative regulation of dna metabolic process
|
GO:0051053 |
57 |
0.381
|
|
|
|
regulation of system process
|
GO:0044057 |
101 |
0.377
|
Mouse |
|
|
regulation of intracellular protein transport
|
GO:0033157 |
123 |
0.376
|
Human |
|
|
endothelium development
|
GO:0003158 |
33 |
0.376
|
Human Mouse |
|
|
positive regulation of protein import into nucleus
|
GO:0042307 |
46 |
0.375
|
Human |
|
|
neurogenesis
|
GO:0022008 |
169 |
0.373
|
Mouse |
|
|
regulation of muscle organ development
|
GO:0048634 |
27 |
0.372
|
|
|
|
lung alveolus development
|
GO:0048286 |
4 |
0.372
|
Mouse |
|
|
neuron development
|
GO:0048666 |
113 |
0.366
|
Mouse |
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.365
|
Human |
|
|
positive regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043280 |
69 |
0.365
|
Human |
|
|
regulation of adherens junction organization
|
GO:1903391 |
21 |
0.363
|
Human |
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.361
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.359
|
|
|
|
protein targeting
|
GO:0006605 |
187 |
0.358
|
Human |
|
|
focal adhesion assembly
|
GO:0048041 |
30 |
0.357
|
Human |
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
394 |
0.354
|
|
|
|
regulation of osteoblast differentiation
|
GO:0045667 |
38 |
0.353
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
391 |
0.352
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.348
|
Human |
|
|
cell substrate adhesion
|
GO:0031589 |
132 |
0.348
|
Human |
|
|
dorsal ventral pattern formation
|
GO:0009953 |
15 |
0.342
|
Human |
|
|
forebrain regionalization
|
GO:0021871 |
3 |
0.341
|
|
|
|
neuromuscular junction development
|
GO:0007528 |
3 |
0.340
|
Fly |
|
|
appendage morphogenesis
|
GO:0035107 |
16 |
0.335
|
Human |
|
|
dna biosynthetic process
|
GO:0071897 |
40 |
0.334
|
|
|
|
positive regulation of reactive oxygen species metabolic process
|
GO:2000379 |
24 |
0.333
|
Human |
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.332
|
Human |
|
|
regulation of cell proliferation involved in kidney development
|
GO:1901722 |
3 |
0.331
|
|
|
|
negative regulation of glomerular mesangial cell proliferation
|
GO:0072125 |
2 |
0.329
|
|
|
|
cartilage development
|
GO:0051216 |
31 |
0.326
|
|
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043281 |
116 |
0.325
|
Human |
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
244 |
0.324
|
|
|
|
vasodilation
|
GO:0042311 |
4 |
0.320
|
|
|
|
cellular response to bmp stimulus
|
GO:0071773 |
8 |
0.316
|
Human |
|
|
determination of dorsal ventral asymmetry
|
GO:0048262 |
4 |
0.315
|
Human |
|
|
cardiovascular system development
|
GO:0072358 |
262 |
0.315
|
Human Zebrafish Mouse |
|
|
hindlimb morphogenesis
|
GO:0035137 |
2 |
0.314
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.313
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.312
|
|
|
|
skeletal system development
|
GO:0001501 |
79 |
0.309
|
|
|
|
muscle tissue development
|
GO:0060537 |
62 |
0.307
|
Human |
|
|
regulation of biomineral tissue development
|
GO:0070167 |
31 |
0.307
|
|
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.306
|
|
|
|
g1 s transition of mitotic cell cycle
|
GO:0000082 |
78 |
0.305
|
Human |
|
|
cell growth
|
GO:0016049 |
160 |
0.304
|
|
|
|
positive regulation of cellular component movement
|
GO:0051272 |
181 |
0.304
|
|
|
|
cell activation
|
GO:0001775 |
213 |
0.304
|
|
|
|
organ formation
|
GO:0048645 |
3 |
0.303
|
|
|
|
execution phase of apoptosis
|
GO:0097194 |
32 |
0.302
|
Human |
|
|
heart valve morphogenesis
|
GO:0003179 |
8 |
0.301
|
Human |
|
|
positive regulation of activin receptor signaling pathway
|
GO:0032927 |
6 |
0.300
|
Human |
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.299
|
Human |
|
|
regulation of dna metabolic process
|
GO:0051052 |
153 |
0.298
|
|
|
|
regulation of protein import into nucleus
|
GO:0042306 |
78 |
0.295
|
Human |
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.293
|
Human |
|
|
morphogenesis of an endothelium
|
GO:0003159 |
6 |
0.293
|
Human |
|
|
protein localization to nucleus
|
GO:0034504 |
136 |
0.293
|
Human |
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.292
|
Human |
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
239 |
0.292
|
|
|
|
mesodermal cell fate commitment
|
GO:0001710 |
2 |
0.291
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.290
|
Mouse |
|
|
erythrocyte differentiation
|
GO:0030218 |
28 |
0.290
|
Human |
|
|
epithelial tube morphogenesis
|
GO:0060562 |
38 |
0.287
|
Human Zebrafish |
|
|
maintenance of protein location in nucleus
|
GO:0051457 |
12 |
0.285
|
|
|
|
regulation of cell growth
|
GO:0001558 |
135 |
0.283
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.282
|
Human |
|
|
negative regulation of focal adhesion assembly
|
GO:0051895 |
5 |
0.282
|
Human |
|
|
negative regulation of platelet aggregation
|
GO:0090331 |
3 |
0.278
|
|
|
|
connective tissue development
|
GO:0061448 |
39 |
0.278
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
162 |
0.276
|
Human |
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.275
|
Human |
|
|
negative regulation of muscle contraction
|
GO:0045932 |
3 |
0.274
|
|
|
|
regulation of endopeptidase activity
|
GO:0052548 |
170 |
0.274
|
Human |
|
|
negative regulation of dna biosynthetic process
|
GO:2000279 |
11 |
0.274
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.271
|
|
|
|
negative regulation of cell differentiation
|
GO:0045596 |
171 |
0.271
|
|
|
|
circulatory system development
|
GO:0072359 |
262 |
0.268
|
Human Zebrafish Mouse |
|
|
muscle contraction
|
GO:0006936 |
73 |
0.266
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
195 |
0.265
|
Human |
|
|
nucleotide catabolic process
|
GO:0009166 |
408 |
0.265
|
|
|
|
positive regulation of epithelial cell migration
|
GO:0010634 |
55 |
0.263
|
|
|
|
locomotory behavior
|
GO:0007626 |
1 |
0.263
|
|
|
|
cell substrate junction assembly
|
GO:0007044 |
35 |
0.262
|
Human |
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.262
|
|
|
|
striated muscle cell differentiation
|
GO:0051146 |
43 |
0.261
|
Human |
|
|
negative regulation of activin receptor signaling pathway
|
GO:0032926 |
6 |
0.261
|
Human |
|
|
embryonic morphogenesis
|
GO:0048598 |
85 |
0.261
|
Human Zebrafish Mouse |
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
412 |
0.259
|
|
|
|
cardiac muscle cell differentiation
|
GO:0055007 |
15 |
0.259
|
Human |
|
|
chondrocyte development
|
GO:0002063 |
1 |
0.258
|
|
|
|
nuclear import
|
GO:0051170 |
106 |
0.257
|
Human |
|
|
ameboidal type cell migration
|
GO:0001667 |
135 |
0.257
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
181 |
0.255
|
Mouse |
|
|
heart contraction
|
GO:0060047 |
62 |
0.255
|
|
|
|
mineralocorticoid metabolic process
|
GO:0008212 |
9 |
0.254
|
|
|
|
regulation of protein localization to nucleus
|
GO:1900180 |
85 |
0.253
|
Human |
|
|
nucleocytoplasmic transport
|
GO:0006913 |
176 |
0.253
|
Human |
|
|
positive regulation of cell migration
|
GO:0030335 |
172 |
0.253
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
205 |
0.251
|
|
|
|
wound healing spreading of cells
|
GO:0044319 |
8 |
0.249
|
Human |
|
|
regulation of transforming growth factor beta receptor signaling pathway
|
GO:0017015 |
48 |
0.248
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
269 |
0.247
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.247
|
Human |
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.246
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.246
|
Human |
|
|
morphogenesis of an epithelium
|
GO:0002009 |
60 |
0.245
|
Human Zebrafish |
|
|
response to lipid
|
GO:0033993 |
206 |
0.243
|
Human |
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.240
|
|
|
|
endodermal mesodermal cell signaling
|
GO:0003133 |
3 |
0.239
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.238
|
|
|
|
maintenance of location in cell
|
GO:0051651 |
62 |
0.236
|
|
|
|
epithelium migration
|
GO:0090132 |
119 |
0.236
|
|
|
|
actin filament based process
|
GO:0030029 |
224 |
0.235
|
|
|
|
immune response
|
GO:0006955 |
307 |
0.234
|
Human |
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.233
|
|
|
|
response to bmp
|
GO:0071772 |
8 |
0.233
|
Human |
|
|
protein modification by small protein conjugation
|
GO:0032446 |
342 |
0.230
|
Human |
|
|
defense response
|
GO:0006952 |
315 |
0.228
|
|
|
|
heart process
|
GO:0003015 |
62 |
0.227
|
|
|
|
tissue morphogenesis
|
GO:0048729 |
96 |
0.226
|
Human Zebrafish Mouse |
|
|
mesoderm development
|
GO:0007498 |
14 |
0.223
|
Mouse |
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.221
|
|
|
|
gtp catabolic process
|
GO:0006184 |
237 |
0.220
|
|
|
|
blastoderm segmentation
|
GO:0007350 |
2 |
0.218
|
|
|
|
response to hormone
|
GO:0009725 |
175 |
0.218
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.217
|
Human |
|
|
forebrain development
|
GO:0030900 |
26 |
0.216
|
|
|
|
muscle structure development
|
GO:0061061 |
98 |
0.213
|
Human |
|
|
regulation of striated muscle tissue development
|
GO:0016202 |
26 |
0.213
|
|
|
|
endoderm formation
|
GO:0001706 |
33 |
0.213
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.213
|
Mouse Fly |
|
|
short term memory
|
GO:0007614 |
1 |
0.212
|
|
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
144 |
0.212
|
Human Mouse |
|
|
lateral mesoderm development
|
GO:0048368 |
1 |
0.209
|
|
|
|
regulation of protein targeting
|
GO:1903533 |
91 |
0.208
|
Human |
|
|
positive regulation of immune system process
|
GO:0002684 |
283 |
0.206
|
Human |
|
|
regulation of glomerular mesangial cell proliferation
|
GO:0072124 |
3 |
0.204
|
|
|
|
cell junction organization
|
GO:0034330 |
79 |
0.203
|
Human |
|
|
regulation of growth
|
GO:0040008 |
165 |
0.203
|
|
|
|
response to alcohol
|
GO:0097305 |
64 |
0.200
|
Human |
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.200
|
Human |
|
|
regulation of platelet aggregation
|
GO:0090330 |
4 |
0.198
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.197
|
Human |
|
|
limb development
|
GO:0060173 |
23 |
0.196
|
Human Mouse |
|
|
regulation of glomerulus development
|
GO:0090192 |
3 |
0.195
|
|
|
|
transforming growth factor beta receptor signaling pathway
|
GO:0007179 |
76 |
0.194
|
Human |
|
|
purine nucleotide catabolic process
|
GO:0006195 |
405 |
0.193
|
|
|
|
mesoderm morphogenesis
|
GO:0048332 |
11 |
0.193
|
Mouse |
|
|
positive regulation of developmental growth
|
GO:0048639 |
16 |
0.192
|
Mouse Fly |
|
|
purine containing compound catabolic process
|
GO:0072523 |
411 |
0.190
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
264 |
0.187
|
|
|
|
regulation of muscle contraction
|
GO:0006937 |
45 |
0.187
|
|
|
|
cell proliferation involved in kidney development
|
GO:0072111 |
3 |
0.187
|
|
|
|
heart development
|
GO:0007507 |
95 |
0.186
|
Human Zebrafish |
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
209 |
0.186
|
|
|
|
positive regulation of mesenchymal cell proliferation
|
GO:0002053 |
2 |
0.186
|
|
|
|
positive regulation of protein transport
|
GO:0051222 |
135 |
0.186
|
Human |
|
|
maintenance of location
|
GO:0051235 |
112 |
0.182
|
|
|
|
response to transforming growth factor beta
|
GO:0071559 |
94 |
0.181
|
Human |
|
|
chondrocyte differentiation
|
GO:0002062 |
17 |
0.180
|
|
|
|
immune system development
|
GO:0002520 |
195 |
0.179
|
Human |
|
|
lymph vessel development
|
GO:0001945 |
9 |
0.177
|
Human Mouse |
|
|
homeostasis of number of cells
|
GO:0048872 |
40 |
0.176
|
Human |
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.174
|
Human Mouse |
|
|
negative regulation of blood coagulation
|
GO:0030195 |
22 |
0.173
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
92 |
0.172
|
Mouse |
|
|
positive regulation of endothelial cell migration
|
GO:0010595 |
39 |
0.169
|
|
|
|
pattern specification process
|
GO:0007389 |
43 |
0.169
|
Human Zebrafish Mouse |
|
|
regulation of map kinase activity
|
GO:0043405 |
108 |
0.168
|
Human |
|
|
response to starvation
|
GO:0042594 |
59 |
0.168
|
|
|
|
cellular response to nutrient levels
|
GO:0031669 |
69 |
0.168
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
204 |
0.165
|
Human |
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.165
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.165
|
Human |
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.164
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.164
|
Human |
|
|
inflammatory response
|
GO:0006954 |
79 |
0.164
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.163
|
|
|
|
regulation of cell matrix adhesion
|
GO:0001952 |
42 |
0.162
|
Human |
|
|
negative regulation of growth
|
GO:0045926 |
97 |
0.162
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.161
|
|
|
|
maintenance of protein location
|
GO:0045185 |
57 |
0.159
|
|
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.159
|
Human |
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
398 |
0.158
|
|
|
|
blood coagulation
|
GO:0007596 |
76 |
0.157
|
|
|
|
regulation of gtpase activity
|
GO:0043087 |
180 |
0.156
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
149 |
0.156
|
Human |
|
|
second messenger mediated signaling
|
GO:0019932 |
78 |
0.156
|
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
155 |
0.155
|
|
|
|
regulation of dna biosynthetic process
|
GO:2000278 |
18 |
0.154
|
|
|
|
protein targeting to nucleus
|
GO:0044744 |
104 |
0.152
|
Human |
|
|
epithelium development
|
GO:0060429 |
227 |
0.151
|
Human Zebrafish Mouse |
|
|
muscle organ development
|
GO:0007517 |
56 |
0.149
|
|
|
|
maintenance of protein location in cell
|
GO:0032507 |
56 |
0.149
|
|
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.148
|
Human |
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.145
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
189 |
0.143
|
|
|
|
cell substrate adherens junction assembly
|
GO:0007045 |
30 |
0.143
|
Human |
|
|
negative regulation of transcription from rna polymerase ii promoter
|
GO:0000122 |
281 |
0.143
|
|
|
|
negative regulation of mesenchymal cell proliferation
|
GO:0072201 |
3 |
0.142
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
392 |
0.142
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
113 |
0.142
|
|
|
|
cell fate commitment
|
GO:0045165 |
27 |
0.142
|
Human Fly |
|
|
somitogenesis
|
GO:0001756 |
2 |
0.140
|
|
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
127 |
0.139
|
|
|
|
negative regulation of transforming growth factor beta receptor signaling pathway
|
GO:0030512 |
28 |
0.139
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.139
|
|
|
|
anterior posterior axis specification
|
GO:0009948 |
2 |
0.139
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
205 |
0.137
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.134
|
Human |
|
|
innate immune response
|
GO:0045087 |
178 |
0.134
|
|
|
|
regulation of blood vessel size
|
GO:0050880 |
18 |
0.133
|
Mouse |
|
|
regulation of muscle tissue development
|
GO:1901861 |
26 |
0.133
|
|
|
|
urogenital system development
|
GO:0001655 |
65 |
0.132
|
|
|
|
regulation of cell activation
|
GO:0050865 |
125 |
0.132
|
|
|
|
negative regulation of protein serine threonine kinase activity
|
GO:0071901 |
57 |
0.131
|
|
|
|
cellular component disassembly
|
GO:0022411 |
92 |
0.131
|
Human |
|
|
regulation of mesoderm development
|
GO:2000380 |
4 |
0.131
|
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
142 |
0.130
|
Human |
|
|
pharyngeal system development
|
GO:0060037 |
2 |
0.130
|
|
|
|
endothelial cell fate commitment
|
GO:0060839 |
3 |
0.130
|
Human |
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.130
|
Human |
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.128
|
|
|
|
actin filament organization
|
GO:0007015 |
128 |
0.127
|
|
|
|
negative regulation of locomotion
|
GO:0040013 |
118 |
0.127
|
Human |
|
|
appendage development
|
GO:0048736 |
23 |
0.124
|
Human Mouse |
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
4 |
0.123
|
|
|
|
behavior
|
GO:0007610 |
112 |
0.122
|
Mouse |
|
|
ion homeostasis
|
GO:0050801 |
230 |
0.121
|
|
|
|
regulation of blood coagulation
|
GO:0030193 |
42 |
0.121
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
128 |
0.121
|
|
|
|
head development
|
GO:0060322 |
108 |
0.120
|
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
125 |
0.119
|
|
|
|
negative regulation of homotypic cell cell adhesion
|
GO:0034111 |
3 |
0.119
|
|
|
|
cell junction assembly
|
GO:0034329 |
67 |
0.119
|
Human |
|
|
biomineral tissue development
|
GO:0031214 |
39 |
0.118
|
|
|
|
embryonic organ development
|
GO:0048568 |
36 |
0.117
|
Human Zebrafish |
|
|
determination of left right symmetry
|
GO:0007368 |
11 |
0.116
|
Zebrafish |
|
|
cellular response to glucocorticoid stimulus
|
GO:0071385 |
4 |
0.116
|
|
|
|
regulation of nervous system development
|
GO:0051960 |
88 |
0.115
|
Mouse Fly |
|
|
brain development
|
GO:0007420 |
97 |
0.115
|
|
|
|
positive regulation of homeostatic process
|
GO:0032846 |
47 |
0.114
|
Human |
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
147 |
0.114
|
|
|
|
maintenance of protein localization in organelle
|
GO:0072595 |
15 |
0.114
|
|
|
|
stem cell differentiation
|
GO:0048863 |
93 |
0.114
|
Human |
|
|
negative regulation of response to wounding
|
GO:1903035 |
47 |
0.113
|
|
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.113
|
Human |
|
|
mesenchymal to epithelial transition involved in metanephros morphogenesis
|
GO:0003337 |
4 |
0.113
|
|
|
|
embryonic heart tube development
|
GO:0035050 |
9 |
0.112
|
Human Zebrafish |
|
|
positive regulation of nucleocytoplasmic transport
|
GO:0046824 |
54 |
0.112
|
Human |
|
|
single organism reproductive process
|
GO:0044702 |
98 |
0.112
|
Human Mouse |
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.112
|
|
|
|
regulation of response to external stimulus
|
GO:0032101 |
222 |
0.111
|
Mouse |
|
|
positive regulation of dna replication
|
GO:0045740 |
35 |
0.110
|
|
