IMP

Process View

Homo sapiens

2 genes annotated in human

Multi-species View

atrioventricular valve morphogenesis

GO:0003181

The process in which the structure of the atrioventricular valve is generated and organized.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "atrioventricular valve morphogenesis"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "atrioventricular valve morphogenesis" (in gray)

Name	Description	Probability	Func Analog Organism
JAG1	jagged 1	1.000
FKBP1A	FK506 binding protein 1A, 12kDa	0.997
BMPR1A	bone morphogenetic protein receptor, type IA	0.992	Human
TGFB1	transforming growth factor, beta 1	0.977
NKX2-5	NK2 transcription factor related, locus 5 (Drosophila)	0.974
BMP2	bone morphogenetic protein 2	0.965	Mouse
BMPR2	bone morphogenetic protein receptor, type II (serine/threonine kinase)	0.940	Human
NOTCH1	notch 1	0.897
FSTL1	follistatin-like 1	0.826
SKIL	SKI-like oncogene	0.795
NOTCH3	notch 3	0.791	Human
RBPJ	recombination signal binding protein for immunoglobulin kappa J region	0.686
TAL1	T-cell acute lymphocytic leukemia 1	0.656
GDF5	growth differentiation factor 5	0.637
TGFB3	transforming growth factor, beta 3	0.529
ENG	endoglin	0.456
CXXC5	CXXC finger protein 5	0.377
CTNNBIP1	catenin, beta interacting protein 1	0.363
SETD8	SET domain containing (lysine methyltransferase) 8	0.341
DLL1	delta-like 1 (Drosophila)	0.249
MAPK8	mitogen-activated protein kinase 8	0.248
PRKG1	protein kinase, cGMP-dependent, type I	0.247
ACVR1	activin A receptor, type I	0.246
SMAD2	SMAD family member 2	0.228
XRCC6	X-ray repair complementing defective repair in Chinese hamster cells 6	0.223
SMAD7	SMAD family member 7	0.202
ZMYND11	zinc finger, MYND-type containing 11	0.190
SMURF2	SMAD specific E3 ubiquitin protein ligase 2	0.179
GATA1	GATA binding protein 1 (globin transcription factor 1)	0.155
MAML1	mastermind-like 1 (Drosophila)	0.137
JAG2	jagged 2	0.135
NRP1	neuropilin 1	0.122
GSK3B	glycogen synthase kinase 3 beta	0.118
SKI	v-ski sarcoma viral oncogene homolog (avian)	0.112
XIAP	X-linked inhibitor of apoptosis	0.106
CTNNB1	catenin (cadherin-associated protein), beta 1, 88kDa	0.101
GATA4	GATA binding protein 4	0.089	Mouse
CTGF	connective tissue growth factor	0.088
TBX5	T-box 5	0.086	Zebrafish Mouse
BMP4	bone morphogenetic protein 4	0.081
DAB2	disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)	0.076
PAPPA	pregnancy-associated plasma protein A, pappalysin 1	0.074
SMAD1	SMAD family member 1	0.070
NEDD4L	neural precursor cell expressed, developmentally down-regulated 4-like	0.047
CTNNA1	catenin (cadherin-associated protein), alpha 1, 102kDa	0.046
MARCKSL1	MARCKS-like 1	0.046
FBLN1	fibulin 1	0.044
TCF7L2	transcription factor 7-like 2 (T-cell specific, HMG-box)	0.042
NOTCH2	notch 2	0.041	Human
ITGA5	integrin, alpha 5 (fibronectin receptor, alpha polypeptide)	0.040
TGFBR1	transforming growth factor, beta receptor 1	0.039	Human
AMOTL2	angiomotin like 2	0.038
PDGFRA	platelet-derived growth factor receptor, alpha polypeptide	0.037
PDGFC	platelet derived growth factor C	0.037
DCP1A	DCP1 decapping enzyme homolog A (S. cerevisiae)	0.036
NOG	noggin	0.034
ADAMTS1	ADAM metallopeptidase with thrombospondin type 1 motif, 1	0.033
SP1	Sp1 transcription factor	0.033
TCF3	transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)	0.033
APC	adenomatous polyposis coli	0.028
ANKRD13A	ankyrin repeat domain 13A	0.027
SMURF1	SMAD specific E3 ubiquitin protein ligase 1	0.025
EGFL7	EGF-like-domain, multiple 7	0.024
RBPMS	RNA binding protein with multiple splicing	0.023
PIAS1	protein inhibitor of activated STAT, 1	0.022
TCF12	transcription factor 12	0.022
SMAD6	SMAD family member 6	0.022
CTBP2	C-terminal binding protein 2	0.022
MMP2	matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)	0.022
ZFYVE9	zinc finger, FYVE domain containing 9	0.021
CTNND1	catenin (cadherin-associated protein), delta 1	0.021
KLF13	Kruppel-like factor 13	0.021
ZEB2	zinc finger E-box binding homeobox 2	0.021
ATXN1L	ataxin 1-like	0.021
WDYHV1	WDYHV motif containing 1	0.021
EFNB2	ephrin-B2	0.021
GADD45B	growth arrest and DNA-damage-inducible, beta	0.021
CAMSAP1	calmodulin regulated spectrin-associated protein 1	0.020
NCOR1	nuclear receptor corepressor 1	0.020
HEY1	hairy/enhancer-of-split related with YRPW motif 1	0.019	Mouse
TGFBR3	transforming growth factor, beta receptor III	0.019
RXRA	retinoid X receptor, alpha	0.018
HAND2	heart and neural crest derivatives expressed 2	0.018
GABPA	GA binding protein transcription factor, alpha subunit 60kDa	0.018
ELK1	ELK1, member of ETS oncogene family	0.018
FOXF2	forkhead box F2	0.018
RAMP2	receptor (G protein-coupled) activity modifying protein 2	0.017
MKL2	MKL/myocardin-like 2	0.017
YAP1	Yes-associated protein 1	0.016
HES1	hairy and enhancer of split 1, (Drosophila)	0.016
VEGFA	vascular endothelial growth factor A	0.016
GATA2	GATA binding protein 2	0.016	Zebrafish
TGFB2	transforming growth factor, beta 2	0.016
HIPK1	homeodomain interacting protein kinase 1	0.015
USP15	ubiquitin specific peptidase 15	0.015
DIP2A	DIP2 disco-interacting protein 2 homolog A (Drosophila)	0.015
ZZEF1	zinc finger, ZZ-type with EF-hand domain 1	0.015
VPS24	vacuolar protein sorting 24 homolog (S. cerevisiae)	0.015
ZBED5	zinc finger, BED-type containing 5	0.015
HOXA5	homeobox A5	0.014
NPR1	natriuretic peptide receptor A/guanylate cyclase A (atrionatriuretic peptide receptor A)	0.014
DACH1	dachshund homolog 1 (Drosophila)	0.014
UBE2I	ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast)	0.014
MED25	mediator complex subunit 25	0.014
PDGFB	platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)	0.014
HIC1	hypermethylated in cancer 1	0.014
DLC1	deleted in liver cancer 1	0.014
WFIKKN2	WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2	0.014
TFPI2	tissue factor pathway inhibitor 2	0.014
TSKU	tsukushi small leucine rich proteoglycan homolog (Xenopus laevis)	0.014
SOX13	SRY (sex determining region Y)-box 13	0.014
SNIP1	Smad nuclear interacting protein 1	0.013
CDH5	cadherin 5, type 2 (vascular endothelium)	0.013
ANTXR2	anthrax toxin receptor 2	0.013
CALD1	caldesmon 1	0.013
SOX17	SRY (sex determining region Y)-box 17	0.013
PLCD3	phospholipase C, delta 3	0.013
DSG2	desmoglein 2	0.013
PLK2	polo-like kinase 2	0.013
FNDC3B	fibronectin type III domain containing 3B	0.013
ID1	inhibitor of DNA binding 1, dominant negative helix-loop-helix protein	0.013
EGR1	early growth response 1	0.013
INHBB	inhibin, beta B	0.013
SOX7	SRY (sex determining region Y)-box 7	0.013
NEDD9	neural precursor cell expressed, developmentally down-regulated 9	0.013
TBX2	T-box 2	0.013
ID3	inhibitor of DNA binding 3, dominant negative helix-loop-helix protein	0.013
NID1	nidogen 1	0.013
ZNF512B	zinc finger protein 512B	0.013
HEG1	HEG homolog 1 (zebrafish)	0.012
STC1	stanniocalcin 1	0.012
CDH1	cadherin 1, type 1, E-cadherin (epithelial)	0.012
ACVR2B	activin A receptor, type IIB	0.012
FZD7	frizzled homolog 7 (Drosophila)	0.012
THBS1	thrombospondin 1	0.012
RUNX1	runt-related transcription factor 1	0.012
PDGFA	platelet-derived growth factor alpha polypeptide	0.012
NIN	ninein (GSK3B interacting protein)	0.012
FERMT2	fermitin family member 2	0.012
NLK	nemo-like kinase	0.012
CNN3	calponin 3, acidic	0.012
DLL4	delta-like 4 (Drosophila)	0.012
TGFBR2	transforming growth factor, beta receptor II (70/80kDa)	0.012	Human
TRAK1	trafficking protein, kinesin binding 1	0.012
HIPK2	homeodomain interacting protein kinase 2	0.012
ABTB1	ankyrin repeat and BTB (POZ) domain containing 1	0.012
APP	amyloid beta (A4) precursor protein	0.011
WNT11	wingless-type MMTV integration site family, member 11	0.011
NR0B1	nuclear receptor subfamily 0, group B, member 1	0.011
F3	coagulation factor III (thromboplastin, tissue factor)	0.011
LAPTM5	lysosomal protein transmembrane 5	0.011
FST	follistatin	0.011
ZFP106	zinc finger protein 106 homolog (mouse)	0.011
FGF18	fibroblast growth factor 18	0.011
RFX1	regulatory factor X, 1 (influences HLA class II expression)	0.011
GOLGB1	golgin B1	0.011
LAMC1	laminin, gamma 1 (formerly LAMB2)	0.011
VGLL3	vestigial like 3 (Drosophila)	0.011
SNRNP70	small nuclear ribonucleoprotein 70kDa (U1)	0.011
GATAD2B	GATA zinc finger domain containing 2B	0.011
YY1	YY1 transcription factor	0.010
TRIM62	tripartite motif containing 62	0.010
CD248	CD248 molecule, endosialin	0.010
PCDHB11	protocadherin beta 11	0.010
SNAI1	snail homolog 1 (Drosophila)	0.010
FOXF1	forkhead box F1	0.010
GPR56	G protein-coupled receptor 56	0.010
THAP5	THAP domain containing 5	0.010