|
|
regulation of tor signaling
|
GO:0032006 |
30 |
0.985
|
Human |
|
|
peptidyl serine phosphorylation
|
GO:0018105 |
101 |
0.984
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.981
|
Worm Fly |
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.975
|
Worm Fly |
|
|
tor signaling
|
GO:0031929 |
39 |
0.961
|
Human |
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.939
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.910
|
Human Mouse |
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.889
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.883
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.881
|
|
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
99 |
0.876
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.867
|
|
|
|
cellular glucuronidation
|
GO:0052695 |
16 |
0.852
|
|
|
|
positive regulation of small gtpase mediated signal transduction
|
GO:0051057 |
12 |
0.838
|
Fly |
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.837
|
|
|
|
positive regulation of erk1 and erk2 cascade
|
GO:0070374 |
75 |
0.802
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
0.796
|
|
|
|
mapk cascade
|
GO:0000165 |
288 |
0.792
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.789
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.775
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
155 |
0.761
|
Fly |
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.758
|
|
|
|
positive regulation of lipopolysaccharide mediated signaling pathway
|
GO:0031666 |
4 |
0.736
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.705
|
Worm Fly |
|
|
regulation of protein complex assembly
|
GO:0043254 |
147 |
0.661
|
Human |
|
|
regulation of cellular glucuronidation
|
GO:2001029 |
5 |
0.651
|
|
|
|
regulation of proteasomal protein catabolic process
|
GO:0061136 |
87 |
0.647
|
Human |
|
|
uronic acid metabolic process
|
GO:0006063 |
16 |
0.626
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.594
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.593
|
Human |
|
|
erk1 and erk2 cascade
|
GO:0070371 |
104 |
0.578
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
380 |
0.576
|
Human |
|
|
modification dependent protein catabolic process
|
GO:0019941 |
209 |
0.563
|
Human |
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.534
|
|
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.529
|
Mouse |
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.527
|
|
|
|
peptidyl serine modification
|
GO:0018209 |
106 |
0.509
|
|
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.504
|
Fly |
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
181 |
0.497
|
Fly |
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
206 |
0.485
|
Human |
|
|
regulation of small gtpase mediated signal transduction
|
GO:0051056 |
156 |
0.444
|
Fly |
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.442
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.437
|
Mouse Fly |
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
244 |
0.419
|
Human |
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
212 |
0.414
|
Human |
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.412
|
Human |
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.405
|
|
|
|
regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903050 |
91 |
0.398
|
Human |
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
244 |
0.394
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.392
|
Fly |
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
324 |
0.383
|
|
|
|
positive regulation of glial cell proliferation
|
GO:0060252 |
2 |
0.382
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.370
|
Human |
|
|
cellular response to metal ion
|
GO:0071248 |
43 |
0.363
|
|
|
|
anterior posterior axis specification embryo
|
GO:0008595 |
2 |
0.361
|
Fly |
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.360
|
|
|
|
regulation of cellular protein catabolic process
|
GO:1903362 |
96 |
0.358
|
Human |
|
|
cellular response to calcium ion
|
GO:0071277 |
19 |
0.355
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.346
|
Human |
|
|
anterior posterior axis specification
|
GO:0009948 |
2 |
0.335
|
Fly |
|
|
regulation of peptidyl serine phosphorylation
|
GO:0033135 |
50 |
0.326
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.325
|
Rat |
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.324
|
Mouse |
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.320
|
Mouse |
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.319
|
|
|
|
positive regulation of peptidyl serine phosphorylation
|
GO:0033138 |
42 |
0.317
|
|
|
|
positive regulation of blood vessel endothelial cell migration
|
GO:0043536 |
16 |
0.296
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
177 |
0.290
|
Mouse |
|
|
regulation of lipid catabolic process
|
GO:0050994 |
23 |
0.287
|
|
|
|
cellular protein complex assembly
|
GO:0043623 |
188 |
0.286
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.282
|
Rat |
|
|
segmentation
|
GO:0035282 |
4 |
0.275
|
Fly |
|
|
positive regulation of fibroblast migration
|
GO:0010763 |
3 |
0.269
|
|
|
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
116 |
0.266
|
Mouse |
|
|
regulation of protein catabolic process
|
GO:0042176 |
155 |
0.266
|
Human |
|
|
cellular protein catabolic process
|
GO:0044257 |
261 |
0.265
|
Human |
|
|
blastoderm segmentation
|
GO:0007350 |
2 |
0.256
|
Fly |
|
|
positive regulation of ras gtpase activity
|
GO:0032320 |
117 |
0.239
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.237
|
Mouse |
|
|
proteasomal protein catabolic process
|
GO:0010498 |
176 |
0.228
|
Human |
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.227
|
Mouse Fly |
|
|
gtp metabolic process
|
GO:0046039 |
239 |
0.225
|
|
|
|
actin filament based process
|
GO:0030029 |
224 |
0.221
|
Mouse |
|
|
photoreceptor cell differentiation
|
GO:0046530 |
2 |
0.216
|
Fly |
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.213
|
Mouse |
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.211
|
Mouse Fly |
|
|
glucuronate metabolic process
|
GO:0019585 |
16 |
0.208
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
392 |
0.201
|
|
|
|
positive regulation of cellular component movement
|
GO:0051272 |
181 |
0.199
|
|
|
|
positive regulation of synaptic transmission
|
GO:0050806 |
4 |
0.199
|
Mouse |
|
|
positive regulation of cell motility
|
GO:2000147 |
177 |
0.197
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
166 |
0.196
|
Mouse |
|
|
regulation of actin filament based process
|
GO:0032970 |
141 |
0.195
|
Mouse |
|
|
positive regulation of gliogenesis
|
GO:0014015 |
4 |
0.191
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.185
|
Rat |
|
|
cell division
|
GO:0051301 |
168 |
0.180
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
158 |
0.179
|
Mouse |
|
|
cell adhesion
|
GO:0007155 |
325 |
0.179
|
Mouse |
|
|
oocyte differentiation
|
GO:0009994 |
2 |
0.178
|
|
|
|
long term memory
|
GO:0007616 |
2 |
0.177
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
408 |
0.175
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.175
|
|
|
|
positive regulation of endothelial cell migration
|
GO:0010595 |
39 |
0.174
|
|
|
|
cytoskeleton dependent intracellular transport
|
GO:0030705 |
21 |
0.173
|
|
|
|
neurogenesis
|
GO:0022008 |
169 |
0.171
|
Fly |
|
|
neuron projection development
|
GO:0031175 |
106 |
0.167
|
|
|
|
biological adhesion
|
GO:0022610 |
331 |
0.166
|
Mouse |
|
|
regulation of cell cell adhesion
|
GO:0022407 |
57 |
0.164
|
|
|
|
oocyte development
|
GO:0048599 |
1 |
0.163
|
|
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.161
|
Worm |
|
|
lipid metabolic process
|
GO:0006629 |
381 |
0.161
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.160
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.159
|
|
|
|
positive regulation of map kinase activity
|
GO:0043406 |
80 |
0.156
|
Rat |
|
|
positive regulation of organelle organization
|
GO:0010638 |
195 |
0.156
|
Mouse |
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
404 |
0.154
|
|
|
|
positive regulation of locomotion
|
GO:0040017 |
186 |
0.150
|
|
|
|
gtp catabolic process
|
GO:0006184 |
237 |
0.150
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.149
|
Rat |
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.149
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
207 |
0.147
|
|
|
|
regulation of endothelial cell migration
|
GO:0010594 |
67 |
0.146
|
|
|
|
desmosome assembly
|
GO:0002159 |
4 |
0.145
|
|
|
|
positive regulation of cytoskeleton organization
|
GO:0051495 |
83 |
0.144
|
Mouse |
|
|
ribonucleotide catabolic process
|
GO:0009261 |
405 |
0.142
|
|
|
|
activation of protein kinase activity
|
GO:0032147 |
90 |
0.142
|
Rat |
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.141
|
Fly |
|
|
regulation of glial cell proliferation
|
GO:0060251 |
4 |
0.141
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.141
|
Fly |
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.140
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.139
|
Rat |
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
391 |
0.139
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
408 |
0.139
|
|
|
|
protein polymerization
|
GO:0051258 |
71 |
0.134
|
|
|
|
generation of neurons
|
GO:0048699 |
152 |
0.133
|
Fly |
|
|
positive regulation of gtpase activity
|
GO:0043547 |
166 |
0.130
|
|
|
|
protein autophosphorylation
|
GO:0046777 |
123 |
0.128
|
Fly |
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.128
|
|
|
|
cell projection organization
|
GO:0030030 |
252 |
0.127
|
|
|
|
cell fate determination
|
GO:0001709 |
3 |
0.127
|
|
|
|
regulation of neurogenesis
|
GO:0050767 |
82 |
0.126
|
Fly |
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.126
|
Mouse |
|
|
regulation of gtpase activity
|
GO:0043087 |
180 |
0.125
|
|
|
|
response to wounding
|
GO:0009611 |
168 |
0.120
|
|
|
|
tripartite regional subdivision
|
GO:0007351 |
2 |
0.120
|
Fly |
|
|
autophagy
|
GO:0006914 |
88 |
0.117
|
Fly |
|
|
regulation of platelet aggregation
|
GO:0090330 |
4 |
0.116
|
|
|
|
cellular response to starvation
|
GO:0009267 |
58 |
0.115
|
Fly |
|
|
single organism nuclear import
|
GO:1902593 |
104 |
0.114
|
|
|
|
regulation of autophagy
|
GO:0010506 |
52 |
0.114
|
Fly |
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.114
|
|
|
|
secretion
|
GO:0046903 |
254 |
0.113
|
Mouse |
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
269 |
0.113
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.113
|
|
|
|
vasculature development
|
GO:0001944 |
181 |
0.112
|
|
|
|
blood vessel development
|
GO:0001568 |
172 |
0.112
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
26 |
0.110
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
70 |
0.110
|
Fly |
|
|
cell development
|
GO:0048468 |
328 |
0.109
|
Mouse Fly |
|
|
response to interleukin 1
|
GO:0070555 |
47 |
0.107
|
|
|
|
i kappab phosphorylation
|
GO:0007252 |
7 |
0.106
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
172 |
0.106
|
|
|
|
positive regulation of neurogenesis
|
GO:0050769 |
49 |
0.104
|
Fly |
|
|
negative regulation of macroautophagy
|
GO:0016242 |
4 |
0.102
|
Fly |
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
205 |
0.101
|
|
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.101
|
|
|
|
regulation of ras gtpase activity
|
GO:0032318 |
128 |
0.100
|
|
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.100
|
|
|
|
regulation of cell development
|
GO:0060284 |
161 |
0.100
|
Mouse Fly |
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
170 |
0.098
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.097
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
411 |
0.095
|
|
|
|
response to nitrogen compound
|
GO:1901698 |
184 |
0.095
|
Rat |
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
166 |
0.095
|
|
|
|
histone threonine phosphorylation
|
GO:0035405 |
7 |
0.093
|
|
|
|
axon cargo transport
|
GO:0008088 |
2 |
0.093
|
|
|
|
macroautophagy
|
GO:0016236 |
39 |
0.093
|
Fly |
|
|
cell substrate adhesion
|
GO:0031589 |
132 |
0.092
|
Mouse |
|
|
positive regulation of protein complex assembly
|
GO:0031334 |
86 |
0.091
|
|
|
|
lipid catabolic process
|
GO:0016042 |
84 |
0.089
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.089
|
|
|
|
single organism membrane organization
|
GO:0044802 |
268 |
0.089
|
|
|
|
cellular response to external stimulus
|
GO:0071496 |
111 |
0.089
|
Fly |
|
|
mitotic cell cycle phase transition
|
GO:0044772 |
162 |
0.089
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
195 |
0.088
|
|
|
|
somatic stem cell maintenance
|
GO:0035019 |
4 |
0.088
|
Mouse |
|
|
activation of mapk activity
|
GO:0000187 |
45 |
0.088
|
Rat |
|
|
memory
|
GO:0007613 |
3 |
0.087
|
|
|
|
synaptic vesicle exocytosis
|
GO:0016079 |
3 |
0.085
|
Mouse |
|
|
response to calcium ion
|
GO:0051592 |
46 |
0.085
|
|
|
|
neuropeptide signaling pathway
|
GO:0007218 |
19 |
0.084
|
|
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.082
|
Worm |
|
|
regulation of ion transport
|
GO:0043269 |
189 |
0.082
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
107 |
0.082
|
|
|
|
locomotory behavior
|
GO:0007626 |
1 |
0.082
|
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
176 |
0.081
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.081
|
Rat |
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.081
|
|
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.081
|
Rat |
|
|
regulation of epithelial cell migration
|
GO:0010632 |
93 |
0.079
|
|
|
|
synaptic transmission
|
GO:0007268 |
61 |
0.079
|
Mouse |
|
|
mitochondrion organization
|
GO:0007005 |
156 |
0.077
|
|
|
|
cytokinesis
|
GO:0000910 |
96 |
0.077
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.077
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
342 |
0.076
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.075
|
Rat |
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.075
|
Fly |
|
|
regulation of secretion by cell
|
GO:1903530 |
177 |
0.073
|
Mouse |
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.072
|
Mouse |
|
|
regulation of cellular carbohydrate metabolic process
|
GO:0010675 |
47 |
0.071
|
|
|
|
peptide secretion
|
GO:0002790 |
51 |
0.071
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
394 |
0.071
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
230 |
0.071
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.070
|
Fly |
|
|
platelet activation
|
GO:0030168 |
44 |
0.070
|
|
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.070
|
Mouse |
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
264 |
0.070
|
|
|
|
macrophage activation involved in immune response
|
GO:0002281 |
1 |
0.070
|
|
|
|
cell projection morphogenesis
|
GO:0048858 |
129 |
0.069
|
|
|
|
positive regulation of nf kappab transcription factor activity
|
GO:0051092 |
81 |
0.069
|
|
|
|
positive regulation of response to external stimulus
|
GO:0032103 |
88 |
0.069
|
|
|
|
blood coagulation
|
GO:0007596 |
76 |
0.069
|
|
|
|
regulation of angiogenesis
|
GO:0045765 |
92 |
0.068
|
|
|
|
regulation of carbohydrate metabolic process
|
GO:0006109 |
54 |
0.067
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.067
|
|
|
|
cell part morphogenesis
|
GO:0032990 |
137 |
0.066
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
189 |
0.065
|
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.065
|
Fly |
|
|
metal ion transport
|
GO:0030001 |
272 |
0.064
|
|
|
|
negative regulation of response to extracellular stimulus
|
GO:0032105 |
5 |
0.064
|
Fly |
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
131 |
0.064
|
|
|
|
chromatin modification
|
GO:0016568 |
298 |
0.063
|
|
|
|
response to cytokine
|
GO:0034097 |
232 |
0.063
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.063
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
119 |
0.063
|
Rat |
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
205 |
0.063
|
|
|
|
negative regulation of catabolic process
|
GO:0009895 |
104 |
0.062
|
Fly |
|
|
regulation of vasculature development
|
GO:1901342 |
97 |
0.062
|
|
|
|
regulation of cellular component size
|
GO:0032535 |
82 |
0.062
|
|
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
108 |
0.062
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
239 |
0.062
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
135 |
0.061
|
Mouse Fly |
|
|
wound healing
|
GO:0042060 |
115 |
0.061
|
|
|
|
cell junction organization
|
GO:0034330 |
79 |
0.061
|
|
|
|
neuron development
|
GO:0048666 |
113 |
0.061
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
175 |
0.061
|
Fly |
|
|
neurotransmitter secretion
|
GO:0007269 |
4 |
0.060
|
Mouse |
|
|
regulation of cell morphogenesis
|
GO:0022604 |
153 |
0.060
|
Mouse |
|
|
vesicle transport along microtubule
|
GO:0047496 |
4 |
0.060
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
101 |
0.059
|
|
|
|
positive regulation of ras protein signal transduction
|
GO:0046579 |
12 |
0.059
|
Fly |
|
|
negative regulation of transport
|
GO:0051051 |
176 |
0.059
|
Mouse |
|
|
positive regulation of angiogenesis
|
GO:0045766 |
51 |
0.059
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
108 |
0.058
|
Rat |
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.057
|
|
|
|
cell cell junction organization
|
GO:0045216 |
69 |
0.057
|
|
|
|
growth
|
GO:0040007 |
202 |
0.057
|
Fly |
|
|
negative regulation of rho gtpase activity
|
GO:0034259 |
4 |
0.057
|
|
|
|
activation of mapkk activity
|
GO:0000186 |
18 |
0.057
|
Rat |
|
|
response to other organism
|
GO:0051707 |
261 |
0.057
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.056
|
|
|
|
response to starvation
|
GO:0042594 |
59 |
0.056
|
Fly |
|
|
single organism carbohydrate metabolic process
|
GO:0044723 |
193 |
0.056
|
|
|
|
histone modification
|
GO:0016570 |
251 |
0.055
|
|
|
|
peptidyl threonine phosphorylation
|
GO:0018107 |
41 |
0.055
|
|
|
|
epithelium migration
|
GO:0090132 |
119 |
0.054
|
Fly |
|
|
neuromuscular junction development
|
GO:0007528 |
3 |
0.054
|
|
|
|
cellular homeostasis
|
GO:0019725 |
196 |
0.054
|
|
|
|
positive regulation of rac gtpase activity
|
GO:0032855 |
31 |
0.054
|
|
|
|
establishment or maintenance of cytoskeleton polarity
|
GO:0030952 |
3 |
0.054
|
|
|
|
positive regulation of actin filament polymerization
|
GO:0030838 |
38 |
0.054
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.054
|
Mouse |
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.053
|
Mouse |
|
|
positive regulation of lipid metabolic process
|
GO:0045834 |
50 |
0.053
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
125 |
0.053
|
Mouse Rat |
|
|
single organismal cell cell adhesion
|
GO:0016337 |
148 |
0.053
|
|
|
|
protein import
|
GO:0017038 |
130 |
0.052
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
113 |
0.052
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.052
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.052
|
|
|
|
negative regulation of cellular catabolic process
|
GO:0031330 |
83 |
0.051
|
Fly |
|
|
positive regulation of protein polymerization
|
GO:0032273 |
45 |
0.051
|
|
|
|
protein targeting
|
GO:0006605 |
187 |
0.051
|
|
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
207 |
0.050
|
|
|
|
actin filament polymerization
|
GO:0030041 |
45 |
0.050
|
|
|
|
regionalization
|
GO:0003002 |
29 |
0.050
|
Fly |
|
|
epithelial cell differentiation
|
GO:0030855 |
141 |
0.050
|
Fly |
|
|
muscle contraction
|
GO:0006936 |
73 |
0.050
|
|
|
|
protein processing
|
GO:0016485 |
226 |
0.050
|
|
|
|
covalent chromatin modification
|
GO:0016569 |
254 |
0.050
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
128 |
0.049
|
|
|
|
embryonic morphogenesis
|
GO:0048598 |
85 |
0.049
|
Fly |
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.049
|
Fly |
|
|
actin cytoskeleton organization
|
GO:0030036 |
207 |
0.049
|
Mouse |
|
|
cellular carbohydrate metabolic process
|
GO:0044262 |
84 |
0.048
|
|
|
|
regulation of nervous system development
|
GO:0051960 |
88 |
0.047
|
Fly |
|
|
somatic muscle development
|
GO:0007525 |
1 |
0.047
|
|
|
|
protein targeting to nucleus
|
GO:0044744 |
104 |
0.047
|
|
|
|
cellular response to nutrient levels
|
GO:0031669 |
69 |
0.047
|
Fly |
|
|
cell growth
|
GO:0016049 |
160 |
0.047
|
|
|
|
negative regulation of glial cell apoptotic process
|
GO:0034351 |
6 |
0.046
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.046
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
412 |
0.046
|
|
|
|
mitochondrial calcium ion homeostasis
|
GO:0051560 |
11 |
0.046
|
|
|
|
actin polymerization or depolymerization
|
GO:0008154 |
56 |
0.045
|
|
|
|
microtubule based process
|
GO:0007017 |
210 |
0.045
|
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
166 |
0.045
|
|
|
|
regulation of multi organism process
|
GO:0043900 |
157 |
0.045
|
|
|
|
monocarboxylic acid metabolic process
|
GO:0032787 |
185 |
0.044
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
209 |
0.044
|
|
|
|
regulation of rho protein signal transduction
|
GO:0035023 |
79 |
0.043
|
|
|
|
cell cycle arrest
|
GO:0007050 |
71 |
0.043
|
|
|
|
response to inorganic substance
|
GO:0010035 |
127 |
0.043
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.043
|
|
|
|
regulation of hormone levels
|
GO:0010817 |
125 |
0.043
|
|
|
|
oogenesis
|
GO:0048477 |
2 |
0.043
|
Fly |
|
|
exocytosis
|
GO:0006887 |
71 |
0.043
|
Mouse |
|
|
regulation of actin filament polymerization
|
GO:0030833 |
50 |
0.043
|
|
|
|
angiogenesis
|
GO:0001525 |
147 |
0.042
|
|
|
|
positive regulation of cell cycle
|
GO:0045787 |
140 |
0.042
|
|
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.042
|
|
|
|
regulation of protein maturation
|
GO:1903317 |
150 |
0.041
|
|
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
182 |
0.041
|
|
|
|
maintenance of location
|
GO:0051235 |
112 |
0.041
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.041
|
|
|
|
protein localization to membrane
|
GO:0072657 |
160 |
0.041
|
|
|
|
system process
|
GO:0003008 |
349 |
0.041
|
Mouse |
|
|
cation transport
|
GO:0006812 |
331 |
0.041
|
|
|
|
regulation of synaptic plasticity
|
GO:0048167 |
3 |
0.041
|
Mouse |
|
|
nuclear import
|
GO:0051170 |
106 |
0.041
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
179 |
0.041
|
Mouse |
|
|
establishment of protein localization to plasma membrane
|
GO:0090002 |
68 |
0.040
|
|
|
|
taxis
|
GO:0042330 |
157 |
0.040
|
|
|
|
positive regulation of defense response
|
GO:0031349 |
87 |
0.040
|
|
|
|
membrane organization
|
GO:0061024 |
292 |
0.040
|
|
|
|
sequestering of metal ion
|
GO:0051238 |
24 |
0.040
|
|
|
|
negative regulation of transcription from rna polymerase ii promoter
|
GO:0000122 |
281 |
0.040
|
|
|
|
apoptotic mitochondrial changes
|
GO:0008637 |
57 |
0.040
|
|
|
|
dna replication
|
GO:0006260 |
116 |
0.040
|
|
|
|
chemical homeostasis
|
GO:0048878 |
306 |
0.040
|
|
|
|
pattern recognition receptor signaling pathway
|
GO:0002221 |
48 |
0.040
|
|
|
|
negative regulation of peptidyl serine dephosphorylation
|
GO:1902309 |
1 |
0.039
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.039
|
|
|
|
circulatory system development
|
GO:0072359 |
262 |
0.039
|
|
|
|
cell projection assembly
|
GO:0030031 |
126 |
0.039
|
|
|
|
regulation of secretion
|
GO:0051046 |
194 |
0.038
|
Mouse |
|
|
microtubule based movement
|
GO:0007018 |
32 |
0.038
|
|
|
|
regulation of b cell receptor signaling pathway
|
GO:0050855 |
4 |
0.038
|
|
|
|
purine ribonucleoside monophosphate metabolic process
|
GO:0009167 |
186 |
0.038
|
|
|
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
128 |
0.038
|
|
|
|
protein maturation
|
GO:0051604 |
233 |
0.038
|
|
|
|
axis specification
|
GO:0009798 |
12 |
0.038
|
Fly |
|
|
blood vessel endothelial cell migration
|
GO:0043534 |
42 |
0.037
|
|
|
|
response to extracellular stimulus
|
GO:0009991 |
85 |
0.037
|
Fly |
|
|
negative regulation of response to external stimulus
|
GO:0032102 |
83 |
0.037
|
Fly |
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.037
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
92 |
0.037
|
Mouse Fly |
|
|
fibroblast migration
|
GO:0010761 |
7 |
0.037
|
Mouse |
|
|
nucleocytoplasmic transport
|
GO:0006913 |
176 |
0.037
|
|
|
|
regulation of lipopolysaccharide mediated signaling pathway
|
GO:0031664 |
13 |
0.037
|
|
|
|
regulation of homeostatic process
|
GO:0032844 |
121 |
0.036
|
|
|
|
peptide transport
|
GO:0015833 |
74 |
0.036
|
|
|
|
nucleus localization
|
GO:0051647 |
1 |
0.036
|
|
|
|
hormone secretion
|
GO:0046879 |
65 |
0.036
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
405 |
0.036
|
|
|
|
regulation of actin polymerization or depolymerization
|
GO:0008064 |
56 |
0.036
|
|
|
|
nuclear migration
|
GO:0007097 |
1 |
0.036
|
|
|
|
cellular response to extracellular stimulus
|
GO:0031668 |
72 |
0.035
|
Fly |
|
|
rap protein signal transduction
|
GO:0032486 |
7 |
0.035
|
|
|
|
positive regulation of cell migration involved in sprouting angiogenesis
|
GO:0090050 |
3 |
0.035
|
|
|
|
positive regulation of epithelial cell migration
|
GO:0010634 |
55 |
0.035
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
193 |
0.035
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
227 |
0.035
|
|
|
|
positive regulation of nervous system development
|
GO:0051962 |
54 |
0.035
|
Fly |
|
|
limbic system development
|
GO:0021761 |
3 |
0.035
|
|
|
|
coagulation
|
GO:0050817 |
78 |
0.034
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
156 |
0.034
|
|
|
|
endothelial cell migration
|
GO:0043542 |
86 |
0.034
|
|
|
|
regulation of lipid metabolic process
|
GO:0019216 |
96 |
0.034
|
|
|
|
oxidation reduction process
|
GO:0055114 |
396 |
0.034
|
|
|
|
regulation of jnk cascade
|
GO:0046328 |
73 |
0.034
|
|
|
|
regulation of insulin secretion
|
GO:0050796 |
33 |
0.034
|
|
|
|
neuron projection morphogenesis
|
GO:0048812 |
50 |
0.034
|
|
|
|
positive regulation of lipid catabolic process
|
GO:0050996 |
13 |
0.034
|
|
|
|
activation of innate immune response
|
GO:0002218 |
55 |
0.034
|
|
|
|
cellular response to lipopolysaccharide
|
GO:0071222 |
57 |
0.033
|
|
|
|
positive regulation of epithelial cell proliferation
|
GO:0050679 |
65 |
0.033
|
|
|
|
nuclear transport
|
GO:0051169 |
179 |
0.033
|
|
|
|
regulation of proteasomal ubiquitin dependent protein catabolic process
|
GO:0032434 |
71 |
0.033
|
Human |
|
|
regulation of protein processing
|
GO:0070613 |
150 |
0.033
|
|
|
|
regulation of cell division
|
GO:0051302 |
116 |
0.033
|
|
|
|
positive regulation of cytokinesis
|
GO:0032467 |
29 |
0.033
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
211 |
0.032
|
|
|
|
response to nutrient levels
|
GO:0031667 |
81 |
0.032
|
Fly |
|
|
innate immune response
|
GO:0045087 |
178 |
0.032
|
|
|
|
cardiovascular system development
|
GO:0072358 |
262 |
0.032
|
|
|
|
regulation of neuron projection development
|
GO:0010975 |
57 |
0.032
|
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
180 |
0.032
|
|
|
|
establishment of nucleus localization
|
GO:0040023 |
1 |
0.032
|
|
|
|
regulation of protein polymerization
|
GO:0032271 |
63 |
0.032
|
|
|
|
peptide hormone secretion
|
GO:0030072 |
50 |
0.032
|
|
|
|
negative regulation of protein maturation
|
GO:1903318 |
142 |
0.031
|
|
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
186 |
0.031
|
|
|
|
vesicle localization
|
GO:0051648 |
26 |
0.031
|
Mouse |
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.031
|
|
|
|
establishment of organelle localization
|
GO:0051656 |
59 |
0.031
|
Mouse |
|
|
positive regulation of protein transport
|
GO:0051222 |
135 |
0.031
|
|
|
|
cell cell junction assembly
|
GO:0007043 |
25 |
0.030
|
|
|
|
positive regulation of antigen receptor mediated signaling pathway
|
GO:0050857 |
3 |
0.030
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
180 |
0.030
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
140 |
0.030
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
213 |
0.030
|
|
|
|
positive regulation of cell adhesion
|
GO:0045785 |
84 |
0.030
|
Mouse |
|
|
regulation of intracellular protein transport
|
GO:0033157 |
123 |
0.030
|
|
|
|
regulation of body fluid levels
|
GO:0050878 |
99 |
0.030
|
|
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.030
|
|
|
|
regulation of cytokinesis
|
GO:0032465 |
45 |
0.030
|
|
|
|
negative regulation of phosphatidylinositol 3 kinase signaling
|
GO:0014067 |
4 |
0.029
|
|
|
|
potassium ion transport
|
GO:0006813 |
62 |
0.029
|
|
|
|
regulation of canonical wnt signaling pathway
|
GO:0060828 |
88 |
0.029
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
162 |
0.029
|
|
|
|
golgi organization
|
GO:0007030 |
38 |
0.029
|
|
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.029
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.029
|
|
|
|
regulation of i kappab kinase nf kappab signaling
|
GO:0043122 |
162 |
0.029
|
|
|
|
endomembrane system organization
|
GO:0010256 |
196 |
0.029
|
|
|
|
negative regulation of autophagy
|
GO:0010507 |
14 |
0.029
|
Fly |
|
|
actin filament organization
|
GO:0007015 |
128 |
0.028
|
Mouse |
|
|
establishment or maintenance of microtubule cytoskeleton polarity
|
GO:0030951 |
2 |
0.028
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
136 |
0.028
|
|
|
|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
156 |
0.028
|
Human |
|
|
cellular response to biotic stimulus
|
GO:0071216 |
71 |
0.028
|
|
|
|
positive regulation of cell cycle process
|
GO:0090068 |
106 |
0.028
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.027
|
|
|
|
response to external biotic stimulus
|
GO:0043207 |
261 |
0.027
|
|
|
|
regulation of peptide hormone secretion
|
GO:0090276 |
41 |
0.027
|
|
|
|
chemotaxis
|
GO:0006935 |
157 |
0.027
|
|
|
|
peroxisome degradation
|
GO:0030242 |
1 |
0.027
|
|
|
|
hemostasis
|
GO:0007599 |
76 |
0.027
|
|
|
|
positive regulation of rap gtpase activity
|
GO:0032854 |
8 |
0.027
|
|
|
|
organelle localization
|
GO:0051640 |
84 |
0.027
|
Mouse |
|
|
monosaccharide metabolic process
|
GO:0005996 |
74 |
0.027
|
|
|
|
regulation of endothelial cell proliferation
|
GO:0001936 |
56 |
0.027
|
|
|
|
regulation of cell growth
|
GO:0001558 |
135 |
0.027
|
|
|
|
establishment of protein localization to membrane
|
GO:0090150 |
121 |
0.027
|
|
|
|
atp catabolic process
|
GO:0006200 |
157 |
0.027
|
|
|
|
leukocyte activation
|
GO:0045321 |
164 |
0.027
|
Mouse |
|
|
organelle inheritance
|
GO:0048308 |
2 |
0.026
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
204 |
0.026
|
Rat |
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
149 |
0.026
|
|
|
|
response to oxygen levels
|
GO:0070482 |
100 |
0.026
|
|
|
|
response to lipid
|
GO:0033993 |
206 |
0.026
|
|
|
|
positive regulation of multi organism process
|
GO:0043902 |
56 |
0.026
|
|
|
|
positive regulation of insulin secretion
|
GO:0032024 |
10 |
0.026
|
|
|
|
pattern specification process
|
GO:0007389 |
43 |
0.026
|
Fly |
|
|
mucus secretion
|
GO:0070254 |
1 |
0.026
|
|
|
|
homotypic cell cell adhesion
|
GO:0034109 |
47 |
0.026
|
|
|
|
regulation of peptide transport
|
GO:0090087 |
62 |
0.026
|
|
|
|
negative regulation of cell motility
|
GO:2000146 |
104 |
0.026
|
Mouse |
|
|
negative regulation of homeostatic process
|
GO:0032845 |
59 |
0.026
|
|
|
|
regulation of fibroblast migration
|
GO:0010762 |
7 |
0.025
|
Mouse |
|
|
neurological system process
|
GO:0050877 |
163 |
0.025
|
Mouse |
|
|
positive regulation of jnk cascade
|
GO:0046330 |
52 |
0.025
|
|
|
|
regulation of hormone secretion
|
GO:0046883 |
57 |
0.025
|
|
|
|
immune response activating cell surface receptor signaling pathway
|
GO:0002429 |
45 |
0.025
|
|
|
|
innate immune response activating signal transduction
|
GO:0002758 |
48 |
0.025
|
|
|
|
response to metal ion
|
GO:0010038 |
84 |
0.025
|
|
|
|
cellular potassium ion transport
|
GO:0071804 |
60 |
0.024
|
|
|
|
lipopolysaccharide mediated signaling pathway
|
GO:0031663 |
26 |
0.024
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.024
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.024
|
Mouse |
|
|
secretion by cell
|
GO:0032940 |
226 |
0.024
|
Mouse |
|
|
positive regulation of cell migration
|
GO:0030335 |
172 |
0.024
|
|
|
|
regulation of blood vessel endothelial cell migration
|
GO:0043535 |
30 |
0.024
|
|
|
|
regulation of sequestering of calcium ion
|
GO:0051282 |
41 |
0.024
|
|
|
|
negative regulation of locomotion
|
GO:0040013 |
118 |
0.024
|
Mouse |
|
|
peroxisome organization
|
GO:0007031 |
28 |
0.023
|
|
|
|
negative regulation of proteolysis
|
GO:0045861 |
132 |
0.023
|
|
|
|
cellular response to decreased oxygen levels
|
GO:0036294 |
51 |
0.023
|
|
|
|
response to hypoxia
|
GO:0001666 |
96 |
0.023
|
|
|
|
developmental growth
|
GO:0048589 |
48 |
0.023
|
Fly |
|
|
compound eye development
|
GO:0048749 |
1 |
0.023
|
|
|
|
plasma membrane organization
|
GO:0007009 |
115 |
0.023
|
|
|
|
reactive oxygen species biosynthetic process
|
GO:1903409 |
4 |
0.023
|
|
|
|
reproductive process
|
GO:0022414 |
106 |
0.023
|
Fly |
