Homo sapiens

160 known processes

C3

complement component 3

(Aliases: CPAMD1,ASP,AHUS5,ARMD9)

C3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
negative regulation of protein activation cascade GO:2000258 7 0.979
Human
protein activation cascade GO:0072376 22 0.979
regulation of protein activation cascade GO:2000257 8 0.952
Human Mouse
complement activation GO:0006956 19 0.904
regulation of complement activation GO:0030449 8 0.816
Human Mouse
response to wounding GO:0009611 168 0.776
Human Mouse
inflammatory response GO:0006954 79 0.739
Human Mouse
regulation of response to wounding GO:1903034 101 0.715
Human Mouse
regulation of response to external stimulus GO:0032101 222 0.706
Human Mouse
humoral immune response GO:0006959 49 0.659
response to cytokine GO:0034097 232 0.658
defense response GO:0006952 315 0.629
Human Mouse
acute inflammatory response GO:0002526 21 0.626
Human Mouse
response to bacterium GO:0009617 144 0.608
positive regulation of cytokine production GO:0001819 167 0.602
regulation of acute inflammatory response GO:0002673 13 0.597
Human Mouse
chemical homeostasis GO:0048878 306 0.579
positive regulation of immune system process GO:0002684 283 0.565
muscle cell proliferation GO:0033002 35 0.501
immune effector process GO:0002252 159 0.481
negative regulation of multicellular organismal process GO:0051241 317 0.456
response to external biotic stimulus GO:0043207 261 0.449
response to oxygen containing compound GO:1901700 369 0.435
regulation of protein processing GO:0070613 150 0.434
Human Mouse
negative regulation of complement activation lectin pathway GO:0001869 2 0.424
Human
positive regulation of immune response GO:0050778 159 0.374
protein processing GO:0016485 226 0.366
Human Mouse
cellular response to lipid GO:0071396 127 0.347
response to molecule of bacterial origin GO:0002237 82 0.329
cellular response to cytokine stimulus GO:0071345 181 0.328
cellular response to oxygen containing compound GO:1901701 276 0.307
regulation of immune effector process GO:0002697 91 0.302
Human Mouse
innate immune response GO:0045087 178 0.296
Human
positive regulation of phosphorylation GO:0042327 394 0.285
regulation of cytokine production GO:0001817 232 0.280
negative regulation of hemostasis GO:1900047 22 0.269
cellular response to biotic stimulus GO:0071216 71 0.260
response to other organism GO:0051707 261 0.249
cellular response to molecule of bacterial origin GO:0071219 62 0.247
cellular response to oxidative stress GO:0034599 85 0.245
g protein coupled receptor signaling pathway GO:0007186 207 0.225
regulation of complement activation lectin pathway GO:0001868 2 0.215
Human
regulation of locomotion GO:0040012 329 0.207
Human
cation homeostasis GO:0055080 189 0.203
metal ion homeostasis GO:0055065 169 0.201
positive regulation of transport GO:0051050 336 0.198
negative regulation of response to external stimulus GO:0032102 83 0.192
Human
regulation of body fluid levels GO:0050878 99 0.186
cytokine production GO:0001816 247 0.180
negative regulation of immune system process GO:0002683 136 0.179
Human
negative regulation of response to wounding GO:1903035 47 0.176
protein maturation GO:0051604 233 0.172
Human Mouse
lipid metabolic process GO:0006629 381 0.171
ion homeostasis GO:0050801 230 0.170
response to interferon gamma GO:0034341 39 0.162
positive regulation of cellular amine metabolic process GO:0033240 7 0.159
positive regulation of cytosolic calcium ion concentration GO:0007204 82 0.159
regulation of immune response GO:0050776 201 0.154
positive regulation of cell death GO:0010942 263 0.153
mitochondrial calcium ion homeostasis GO:0051560 11 0.153
cellular response to lipopolysaccharide GO:0071222 57 0.152
immune response GO:0006955 307 0.148
cellular homeostasis GO:0019725 196 0.148
positive regulation of cell motility GO:2000147 177 0.142
positive regulation of protein phosphorylation GO:0001934 313 0.142
response to lipopolysaccharide GO:0032496 70 0.141
calcium ion homeostasis GO:0055074 122 0.139
negative regulation of cell death GO:0060548 345 0.138
positive regulation of protein kinase activity GO:0045860 190 0.136
amine metabolic process GO:0009308 44 0.135
divalent inorganic cation homeostasis GO:0072507 136 0.135
negative regulation of protein maturation GO:1903318 142 0.134
Human
positive regulation of cell adhesion GO:0045785 84 0.133
response to lipid GO:0033993 206 0.132
regulation of blood coagulation GO:0030193 42 0.131
cellular lipid metabolic process GO:0044255 303 0.129
regulation of humoral immune response GO:0002920 11 0.128
Human Mouse
regulation of defense response GO:0031347 154 0.126
Human Mouse
response to biotic stimulus GO:0009607 276 0.124
response to abiotic stimulus GO:0009628 336 0.121
i kappab kinase nf kappab signaling GO:0007249 166 0.117
keratinocyte differentiation GO:0030216 36 0.116
regulation of wound healing GO:0061041 56 0.113
positive regulation of cellular component organization GO:0051130 376 0.113
cellular cation homeostasis GO:0030003 163 0.112
positive regulation of cell proliferation GO:0008284 301 0.110
activation of immune response GO:0002253 114 0.109
negative regulation of blood coagulation GO:0030195 22 0.107
regulation of cellular ketone metabolic process GO:0010565 50 0.107
response to reactive oxygen species GO:0000302 61 0.107
regulation of smooth muscle cell proliferation GO:0048660 28 0.103
response to nitrogen compound GO:1901698 184 0.101
regulation of tumor necrosis factor superfamily cytokine production GO:1903555 44 0.101
skin development GO:0043588 76 0.100
leukocyte activation GO:0045321 164 0.099
cytosolic calcium ion homeostasis GO:0051480 89 0.098
negative regulation of immune effector process GO:0002698 38 0.094
Human
regulation of cell adhesion GO:0030155 166 0.093
cellular response to reactive oxygen species GO:0034614 50 0.092
regulation of cellular amino acid metabolic process GO:0006521 6 0.090
cellular response to interferon gamma GO:0071346 24 0.087
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.086
smooth muscle cell proliferation GO:0048659 28 0.083
cellular amine metabolic process GO:0044106 41 0.083
regulation of cellular amine metabolic process GO:0033238 11 0.083
positive regulation of locomotion GO:0040017 186 0.082
response to inorganic substance GO:0010035 127 0.081
response to organic cyclic compound GO:0014070 204 0.080
epidermal cell differentiation GO:0009913 45 0.079
negative regulation of cell proliferation GO:0008285 228 0.079
regulation of protein maturation GO:1903317 150 0.079
Human Mouse
regulation of macrophage chemotaxis GO:0010758 4 0.078
Human
positive regulation of i kappab kinase nf kappab signaling GO:0043123 132 0.075
regulation of cellular component movement GO:0051270 334 0.074
Human
erk1 and erk2 cascade GO:0070371 104 0.074
cellular calcium ion homeostasis GO:0006874 117 0.072
positive regulation of transferase activity GO:0051347 227 0.072
cellular response to endogenous stimulus GO:0071495 336 0.071
cellular ketone metabolic process GO:0042180 80 0.070
wound healing GO:0042060 115 0.068
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.067
cellular metal ion homeostasis GO:0006875 146 0.067
response to oxidative stress GO:0006979 121 0.066
signal transduction by phosphorylation GO:0023014 297 0.063
positive regulation of defense response GO:0031349 87 0.063
Mouse
t cell activation GO:0042110 99 0.062
positive regulation of cytosolic calcium ion concentration involved in phospholipase c activating g protein coupled signaling pathway GO:0051482 6 0.062
positive regulation of developmental process GO:0051094 314 0.062
Mouse
positive regulation of protein transport GO:0051222 135 0.062
Human
negative regulation of protein metabolic process GO:0051248 391 0.061
Human
cellular chemical homeostasis GO:0055082 180 0.061
regulation of protein transport GO:0051223 213 0.061
Human
cation transport GO:0006812 331 0.061
cellular response to hydrogen peroxide GO:0070301 37 0.060
mapk cascade GO:0000165 288 0.060
plasminogen activation GO:0031639 11 0.060
positive regulation of mitochondrial calcium ion concentration GO:0051561 8 0.059
positive regulation of mapk cascade GO:0043410 190 0.058
positive regulation of kinase activity GO:0033674 204 0.057
regulation of coagulation GO:0050818 44 0.056
cell adhesion GO:0007155 325 0.056
positive regulation of jnk cascade GO:0046330 52 0.056
regulation of cell migration GO:0030334 289 0.056
Human
negative regulation of developmental process GO:0051093 247 0.056
positive regulation of programmed cell death GO:0043068 249 0.055
positive regulation of apoptotic process GO:0043065 246 0.055
cellular response to organic cyclic compound GO:0071407 127 0.055
cellular divalent inorganic cation homeostasis GO:0072503 128 0.054
epithelium development GO:0060429 227 0.054
regulation of cell motility GO:2000145 299 0.053
Human
vesicle mediated transport GO:0016192 371 0.053
protein oligomerization GO:0051259 173 0.052
hemostasis GO:0007599 76 0.052
nervous system development GO:0007399 293 0.052
elastic fiber assembly GO:0048251 3 0.050
regulation of hemostasis GO:1900046 42 0.050
negative regulation of cellular protein metabolic process GO:0032269 353 0.049
Human
negative regulation of endopeptidase activity GO:0010951 84 0.049
Human
regulation of cell activation GO:0050865 125 0.049
positive regulation of hydrolase activity GO:0051345 331 0.048
cellular ion homeostasis GO:0006873 168 0.048
regulation of inflammatory response GO:0050727 46 0.047
Human Mouse
positive regulation of macrophage chemotaxis GO:0010759 3 0.047
positive regulation of secretion by cell GO:1903532 108 0.047
Human
reactive oxygen species metabolic process GO:0072593 75 0.047
regulation of erk1 and erk2 cascade GO:0070372 99 0.046
negative regulation of complement activation GO:0045916 7 0.046
Human
branching involved in salivary gland morphogenesis GO:0060445 1 0.044
negative regulation of apoptotic process GO:0043066 316 0.044
organic hydroxy compound metabolic process GO:1901615 147 0.044
purine ribonucleotide catabolic process GO:0009154 404 0.044
nucleoside phosphate catabolic process GO:1901292 412 0.043
regulation of secretion GO:0051046 194 0.043
Human
peptidyl tyrosine modification GO:0018212 170 0.041
cytokine mediated signaling pathway GO:0019221 109 0.041
fibrinolysis GO:0042730 11 0.040
oxidation reduction process GO:0055114 396 0.040
cell chemotaxis GO:0060326 112 0.039
Human
response to metal ion GO:0010038 84 0.038
negative regulation of hydrolase activity GO:0051346 182 0.038
Human
cell activation GO:0001775 213 0.038
regulation of kinase activity GO:0043549 314 0.038
hemopoiesis GO:0030097 180 0.037
regulation of peptidase activity GO:0052547 180 0.037
Human
biological adhesion GO:0022610 331 0.037
single organismal cell cell adhesion GO:0016337 148 0.037
regulation of transferase activity GO:0051338 355 0.036
response to steroid hormone GO:0048545 80 0.036
steroid metabolic process GO:0008202 94 0.035
positive regulation of intracellular transport GO:0032388 104 0.035
bone mineralization GO:0030282 34 0.035
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.035
cellular amino acid metabolic process GO:0006520 116 0.035
blood vessel remodeling GO:0001974 2 0.034
protein homooligomerization GO:0051260 100 0.034
negative regulation of protein processing GO:0010955 142 0.034
Human
response to mercury ion GO:0046689 4 0.034
regulation of establishment of protein localization GO:0070201 242 0.034
Human
epidermis development GO:0008544 59 0.034
regulation of nucleotide metabolic process GO:0006140 269 0.033
ras protein signal transduction GO:0007265 73 0.033
single organism carbohydrate metabolic process GO:0044723 193 0.033
circulatory system development GO:0072359 262 0.033
Mouse
regulation of proteolysis GO:0030162 293 0.033
Human
lymphocyte activation GO:0046649 133 0.033
immune system development GO:0002520 195 0.033
regulation of lymphocyte proliferation GO:0050670 64 0.033
phospholipase c activating g protein coupled receptor signaling pathway GO:0007200 15 0.032
post embryonic development GO:0009791 2 0.031
multi organism cellular process GO:0044764 156 0.031
regulation of hormone levels GO:0010817 125 0.031
epithelial cell differentiation GO:0030855 141 0.031
nitrogen compound transport GO:0071705 191 0.031
regulation of endopeptidase activity GO:0052548 170 0.030
Human
regulation of vesicle mediated transport GO:0060627 130 0.030
regulation of vasculature development GO:1901342 97 0.030
Mouse
regulation of protein kinase activity GO:0045859 289 0.029
small molecule biosynthetic process GO:0044283 157 0.029
female gamete generation GO:0007292 2 0.029
negative regulation of catalytic activity GO:0043086 335 0.029
Human
lymphocyte migration GO:0072676 28 0.028
cellular response to hormone stimulus GO:0032870 125 0.028
t cell proliferation GO:0042098 45 0.028
positive regulation of erk1 and erk2 cascade GO:0070374 75 0.028
positive regulation of epithelial cell proliferation GO:0050679 65 0.028
negative regulation of endoplasmic reticulum calcium ion concentration GO:0032471 6 0.028
multicellular organismal aging GO:0010259 3 0.028
cell substrate adhesion GO:0031589 132 0.027
regulation of peptidyl tyrosine phosphorylation GO:0050730 108 0.027
positive regulation of cellular component biogenesis GO:0044089 158 0.027
regulation of tumor necrosis factor production GO:0032680 43 0.027
response to hydrogen peroxide GO:0042542 40 0.027
regulation of mapk cascade GO:0043408 262 0.027
thyroid hormone transport GO:0070327 2 0.026
tube development GO:0035295 125 0.026
regulation of protein localization GO:0032880 296 0.026
Human
positive regulation of monocyte chemotactic protein 1 production GO:0071639 3 0.026
nucleoside triphosphate metabolic process GO:0009141 422 0.026
negative regulation of proteolysis GO:0045861 132 0.026
Human
endothelial cell migration GO:0043542 86 0.026
positive regulation of proteolysis GO:0045862 142 0.026
cytokine secretion GO:0050663 64 0.026
Human
positive regulation of response to external stimulus GO:0032103 88 0.026
Mouse
regulation of chemotaxis GO:0050920 74 0.026
Human
purine ribonucleoside metabolic process GO:0046128 437 0.026
peptidyl tyrosine phosphorylation GO:0018108 170 0.026
negative regulation of multi organism process GO:0043901 92 0.026
positive regulation of chemotaxis GO:0050921 57 0.025
leukocyte proliferation GO:0070661 74 0.025
small gtpase mediated signal transduction GO:0007264 78 0.025
positive regulation of secretion GO:0051047 116 0.025
Human
response to alcohol GO:0097305 64 0.025
cdc42 protein signal transduction GO:0032488 4 0.025
vasculature development GO:0001944 181 0.025
Mouse
positive regulation of stress activated protein kinase signaling cascade GO:0070304 61 0.025
regulation of purine nucleotide metabolic process GO:1900542 264 0.025
single organism cellular localization GO:1902580 332 0.025
purine nucleoside triphosphate metabolic process GO:0009144 412 0.024
leukocyte migration GO:0050900 107 0.024
Human
peptidyl lysine modification GO:0018205 144 0.024
fatty acid metabolic process GO:0006631 115 0.024
anatomical structure formation involved in morphogenesis GO:0048646 284 0.024
Mouse
regulation of leukocyte chemotaxis GO:0002688 46 0.024
Human
myeloid dendritic cell chemotaxis GO:0002408 3 0.024
negative regulation of cytokine production GO:0001818 82 0.024
regulation of leukocyte proliferation GO:0070663 67 0.024
positive regulation of nucleotide catabolic process GO:0030813 185 0.024
ribonucleoside triphosphate metabolic process GO:0009199 412 0.024
positive regulation of nucleoside metabolic process GO:0045979 186 0.024
regulation of epithelial cell proliferation GO:0050678 113 0.024
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.023
negative regulation of neurotrophin trk receptor signaling pathway GO:0051387 2 0.023
positive regulation of cell activation GO:0050867 81 0.023
positive regulation of inflammatory response GO:0050729 10 0.023
Mouse
negative regulation of vasculature development GO:1901343 43 0.023
carbohydrate metabolic process GO:0005975 207 0.023
positive regulation of cell differentiation GO:0045597 211 0.023
morphogenesis of a branching epithelium GO:0061138 20 0.023
negative regulation of transport GO:0051051 176 0.022
positive regulation of smooth muscle cell proliferation GO:0048661 14 0.022
tumor necrosis factor production GO:0032640 43 0.022
regulation of leukocyte activation GO:0002694 115 0.022
leukocyte chemotaxis GO:0030595 76 0.022
Human
positive regulation of cd8 positive alpha beta t cell proliferation GO:2000566 1 0.022
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.022
neurogenesis GO:0022008 169 0.022
response to nitric oxide GO:0071731 4 0.022
hormone transport GO:0009914 68 0.022
jnk cascade GO:0007254 80 0.022
gtp catabolic process GO:0006184 237 0.021
regeneration GO:0031099 4 0.021
positive regulation of apoptotic signaling pathway GO:2001235 70 0.021
interspecies interaction between organisms GO:0044419 156 0.021
response to organophosphorus GO:0046683 41 0.021
regulation of transmembrane transport GO:0034762 139 0.021
reactive nitrogen species metabolic process GO:2001057 3 0.021
positive regulation of protein secretion GO:0050714 60 0.021
Human
regulation of behavior GO:0050795 82 0.021
Human
lipid modification GO:0030258 84 0.021
negative regulation of t cell proliferation GO:0042130 8 0.020
response to tumor necrosis factor GO:0034612 76 0.020
positive regulation of response to wounding GO:1903036 28 0.020
Mouse
sulfur compound metabolic process GO:0006790 101 0.020
regulation of t cell proliferation GO:0042129 42 0.020
organ morphogenesis GO:0009887 147 0.020
apoptotic signaling pathway GO:0097190 268 0.020
regulation of cysteine type endopeptidase activity GO:2000116 127 0.020
organonitrogen compound biosynthetic process GO:1901566 200 0.020
purine containing compound catabolic process GO:0072523 411 0.020
response to activity GO:0014823 0 0.020
cellular amide metabolic process GO:0043603 69 0.020
organophosphate catabolic process GO:0046434 430 0.020
response to hormone GO:0009725 175 0.020
purine nucleotide catabolic process GO:0006195 405 0.020
ribonucleoside catabolic process GO:0042454 406 0.020
hematopoietic or lymphoid organ development GO:0048534 186 0.019
cardiovascular system development GO:0072358 262 0.019
Mouse
ribonucleoside triphosphate catabolic process GO:0009203 391 0.019
positive regulation of catabolic process GO:0009896 310 0.019
regulation of cellular response to stress GO:0080135 244 0.019
nuclear transport GO:0051169 179 0.019
organic anion transport GO:0015711 103 0.019
protein secretion GO:0009306 98 0.019
Human
positive regulation of cytoskeleton organization GO:0051495 83 0.019
reactive oxygen species biosynthetic process GO:1903409 4 0.019
secretion by cell GO:0032940 226 0.019
Human
negative regulation of cell activation GO:0050866 33 0.019
negative regulation of locomotion GO:0040013 118 0.019
Human
negative regulation of programmed cell death GO:0043069 321 0.019
cellular macromolecular complex assembly GO:0034622 324 0.019
cellular response to growth factor stimulus GO:0071363 197 0.019
cellular modified amino acid metabolic process GO:0006575 64 0.019
zymogen activation GO:0031638 70 0.019
positive regulation of cell migration GO:0030335 172 0.019
complement activation lectin pathway GO:0001867 7 0.019
Human
coagulation GO:0050817 78 0.019
organic acid transport GO:0015849 65 0.019
cellular component morphogenesis GO:0032989 314 0.019
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.018
intracellular protein transport GO:0006886 270 0.018
carboxylic acid biosynthetic process GO:0046394 97 0.018
regulation of cyclic nucleotide metabolic process GO:0030799 63 0.018
rho protein signal transduction GO:0007266 26 0.018
purine ribonucleoside catabolic process GO:0046130 398 0.018
regulation of lymphocyte activation GO:0051249 103 0.018
cellular protein catabolic process GO:0044257 261 0.018
carbohydrate derivative biosynthetic process GO:1901137 207 0.018
positive regulation of lymphocyte activation GO:0051251 73 0.018
angiogenesis GO:0001525 147 0.018
Mouse
posttranscriptional regulation of gene expression GO:0010608 213 0.018
cellular carbohydrate metabolic process GO:0044262 84 0.018
myeloid cell differentiation GO:0030099 117 0.018
positive regulation of leukocyte activation GO:0002696 80 0.018
regulation of intracellular protein transport GO:0033157 123 0.018
regulation of cytoplasmic transport GO:1903649 149 0.018
regulation of t cell activation GO:0050863 77 0.018
negative regulation of t cell cytokine production GO:0002725 4 0.018
negative regulation of cell differentiation GO:0045596 171 0.018
negative regulation of plasminogen activation GO:0010757 4 0.017
positive regulation of tyrosine phosphorylation of stat protein GO:0042531 28 0.017
hormone secretion GO:0046879 65 0.017
regulation of leukocyte migration GO:0002685 63 0.017
Human
tumor necrosis factor superfamily cytokine production GO:0071706 45 0.017
phospholipid metabolic process GO:0006644 99 0.017
negative regulation of defense response GO:0031348 47 0.017
Human
negative regulation of peptidase activity GO:0010466 91 0.017
Human
regulation of platelet aggregation GO:0090330 4 0.017
embryonic viscerocranium morphogenesis GO:0048703 1 0.017
mature natural killer cell chemotaxis GO:0035782 1 0.017
oogenesis GO:0048477 2 0.017
positive regulation of tumor necrosis factor superfamily cytokine production GO:1903557 22 0.017
peptide metabolic process GO:0006518 51 0.017
carboxylic acid transport GO:0046942 63 0.017
positive regulation of actin filament bundle assembly GO:0032233 25 0.016
mitochondrion organization GO:0007005 156 0.016
negative regulation of intracellular signal transduction GO:1902532 183 0.016
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.016
myeloid leukocyte activation GO:0002274 34 0.016
chemotaxis GO:0006935 157 0.016
Human
negative regulation of blood vessel morphogenesis GO:2000181 41 0.016
neuromuscular junction development GO:0007528 3 0.016
purine nucleoside catabolic process GO:0006152 398 0.016
positive regulation of cytoplasmic transport GO:1903651 82 0.016
negative regulation of cellular component movement GO:0051271 106 0.016
Human
regulation of reactive oxygen species metabolic process GO:2000377 41 0.016
response to acid chemical GO:0001101 66 0.016
dendritic cell antigen processing and presentation GO:0002468 1 0.016
positive regulation of phospholipase activity GO:0010518 22 0.016
endocytosis GO:0006897 159 0.016
negative regulation of phosphate metabolic process GO:0045936 267 0.016
cell projection organization GO:0030030 252 0.016
cell growth GO:0016049 160 0.016
cellular response to dna damage stimulus GO:0006974 379 0.016
negative regulation of cytokine mediated signaling pathway GO:0001960 22 0.016
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 26 0.016
nucleotide catabolic process GO:0009166 408 0.016
regulation of protein catabolic process GO:0042176 155 0.016
cellular macromolecule catabolic process GO:0044265 380 0.016
regulation of granulocyte chemotaxis GO:0071622 16 0.016
glycoprotein metabolic process GO:0009100 110 0.016
epithelium migration GO:0090132 119 0.016
positive regulation of synaptic transmission GO:0050806 4 0.016
negative regulation of cell motility GO:2000146 104 0.015
Human
regulation of intracellular transport GO:0032386 195 0.015
monocarboxylic acid biosynthetic process GO:0072330 67 0.015
iron ion homeostasis GO:0055072 15 0.015
guanosine containing compound metabolic process GO:1901068 244 0.015
positive regulation of organelle organization GO:0010638 195 0.015
glycerolipid metabolic process GO:0046486 107 0.015
renal albumin absorption GO:0097018 1 0.015
regulation of protein secretion GO:0050708 86 0.015
Human
negative regulation of angiogenesis GO:0016525 39 0.015
regulation of nucleoside metabolic process GO:0009118 209 0.015
myeloid leukocyte migration GO:0097529 62 0.015
Human
sequestering of calcium ion GO:0051208 17 0.015
positive regulation of cellular component movement GO:0051272 181 0.015
protein localization to membrane GO:0072657 160 0.015
guanosine containing compound catabolic process GO:1901069 239 0.015
protein import GO:0017038 130 0.014
positive regulation of acute inflammatory response GO:0002675 2 0.014
Mouse
regulation of cellular component biogenesis GO:0044087 281 0.014
purine nucleoside triphosphate catabolic process GO:0009146 392 0.014
negative regulation of blood pressure GO:0045776 3 0.014
behavior GO:0007610 112 0.014
Human
regulation of gtpase activity GO:0043087 180 0.014
negative regulation of platelet derived growth factor receptor signaling pathway GO:0010642 4 0.014
regulation of sterol transport GO:0032371 21 0.014
regulation of stress activated protein kinase signaling cascade GO:0070302 85 0.014
detection of chemical stimulus GO:0009593 55 0.014
secretion GO:0046903 254 0.014
Human
regulation of secretion by cell GO:1903530 177 0.014
Human
epithelial cell migration GO:0010631 119 0.014
peptide secretion GO:0002790 51 0.014
regulation of stress activated mapk cascade GO:0032872 84 0.014
regulation of cytokine secretion GO:0050707 57 0.014
Human
intrinsic apoptotic signaling pathway GO:0097193 127 0.014
regulation of cell cell adhesion GO:0022407 57 0.014
lipid localization GO:0010876 106 0.014
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.014
ribonucleotide catabolic process GO:0009261 405 0.014
ossification GO:0001503 121 0.014
protein localization to nucleus GO:0034504 136 0.014
positive regulation of protein kinase b signaling GO:0051897 42 0.014
negative regulation of cell migration GO:0030336 102 0.013
Human
activation of protein kinase activity GO:0032147 90 0.013
gtp metabolic process GO:0046039 239 0.013
morphogenesis of a branching structure GO:0001763 21 0.013
regulation of anatomical structure morphogenesis GO:0022603 286 0.013
Mouse
regulation of ras gtpase activity GO:0032318 128 0.013
skeletal muscle satellite cell proliferation GO:0014841 1 0.013
cell morphogenesis GO:0000902 296 0.013
organic acid biosynthetic process GO:0016053 97 0.013
single organism reproductive process GO:0044702 98 0.013
response to radiation GO:0009314 151 0.013
aging GO:0007568 66 0.013
sterol transport GO:0015918 39 0.013
regulation of gtp catabolic process GO:0033124 180 0.013
blood vessel morphogenesis GO:0048514 162 0.013
Mouse
positive regulation of t cell proliferation GO:0042102 33 0.013
regulation of renal albumin absorption GO:2000532 1 0.013
regulation of leukocyte differentiation GO:1902105 61 0.013
response to camp GO:0051591 25 0.013
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 90 0.013
positive regulation of nucleotide metabolic process GO:0045981 230 0.013
actin cytoskeleton organization GO:0030036 207 0.013
negative regulation of homotypic cell cell adhesion GO:0034111 3 0.013
spermatid differentiation GO:0048515 4 0.013
lymphocyte proliferation GO:0046651 70 0.013
regulation of cellular response to growth factor stimulus GO:0090287 76 0.013
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.013
regulation of purine nucleotide catabolic process GO:0033121 205 0.013
regulation of protein targeting GO:1903533 91 0.013
regulation of cytoskeleton organization GO:0051493 177 0.013

C3 disease predictions

Disease DO term ID Size Probability Func Analog Org
hemolytic anemia DOID:583 20 1.000
hemolytic uremic syndrome DOID:12554 8 1.000
immune system disease DOID:2914 155 1.000
normocytic anemia DOID:720 20 1.000
anemia DOID:2355 55 1.000
hematopoietic system disease DOID:74 100 1.000
sensory system disease DOID:0050155 203 0.803
eye and adnexa disease DOID:1492 150 0.803
nervous system disease DOID:863 431 0.803
eye disease DOID:5614 149 0.803
retinal disease DOID:5679 118 0.779
retinal degeneration DOID:8466 89 0.779
degeneration of macula and posterior pole DOID:2007 17 0.779
macular degeneration DOID:4448 20 0.779
age related macular degeneration DOID:10871 17 0.779
disease of metabolism DOID:0014667 295 0.165
inherited metabolic disorder DOID:655 242 0.044
primary immunodeficiency disease DOID:612 36 0.033
Human
disease by infectious agent DOID:0050117 34 0.031
acquired metabolic disease DOID:0060158 58 0.023
central nervous system disease DOID:331 186 0.021
Human
cancer DOID:162 167 0.015
disease of cellular proliferation DOID:14566 174 0.015
organ system cancer DOID:0050686 164 0.015
neurodegenerative disease DOID:1289 102 0.014
Human