IMP

Process View

Homo sapiens

20 genes annotated in human

Multi-species View

morphogenesis of a branching epithelium

GO:0061138

The process in which the anatomical structures of a branched epithelium are generated and organized.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "morphogenesis of a branching epithelium"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "morphogenesis of a branching epithelium" (in gray)

Name	Description	Probability	Func Analog Organism
FGFR2	fibroblast growth factor receptor 2	0.972	Mouse Fly
VEGFA	vascular endothelial growth factor A	0.955	Mouse
RARA	retinoic acid receptor, alpha	0.943
CDKN2A	cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4)	0.931
CTNNB1	catenin (cadherin-associated protein), beta 1, 88kDa	0.849	Mouse Fly
TGFBR2	transforming growth factor, beta receptor II (70/80kDa)	0.838	Mouse
FGF1	fibroblast growth factor 1 (acidic)	0.752
NRP1	neuropilin 1	0.694	Mouse
CREBBP	CREB binding protein	0.615
PDGFRA	platelet-derived growth factor receptor, alpha polypeptide	0.595
MDM2	Mdm2 p53 binding protein homolog (mouse)	0.569
SERPINE1	serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1	0.548
THBS1	thrombospondin 1	0.536
COL4A2	collagen, type IV, alpha 2	0.500	Human
BMPR1A	bone morphogenetic protein receptor, type IA	0.491
COL4A1	collagen, type IV, alpha 1	0.457
BCL2L1	BCL2-like 1	0.439
TIMP3	TIMP metallopeptidase inhibitor 3	0.426
FGFR1	fibroblast growth factor receptor 1	0.351	Mouse Fly
FLT1	fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)	0.325	Mouse
COL2A1	collagen, type II, alpha 1	0.311
PTPN1	protein tyrosine phosphatase, non-receptor type 1	0.303
TBX5	T-box 5	0.293
CBL	Cas-Br-M (murine) ecotropic retroviral transforming sequence	0.246
FGF10	fibroblast growth factor 10	0.245
CDH1	cadherin 1, type 1, E-cadherin (epithelial)	0.237	Mouse
FN1	fibronectin 1	0.230
NKX2-1	NK2 homeobox 1	0.213
GAS6	growth arrest-specific 6	0.212
PTPN12	protein tyrosine phosphatase, non-receptor type 12	0.211
JAG1	jagged 1	0.200
FGF2	fibroblast growth factor 2 (basic)	0.189
EIF2C2	eukaryotic translation initiation factor 2C, 2	0.151
COL4A3	collagen, type IV, alpha 3 (Goodpasture antigen)	0.148	Human
HNF4A	hepatocyte nuclear factor 4, alpha	0.146
HOXA10	homeobox A10	0.145
RUNX1	runt-related transcription factor 1	0.140
NCOR2	nuclear receptor corepressor 2	0.137
PTK2	PTK2 protein tyrosine kinase 2	0.137
ITGB4	integrin, beta 4	0.136
CRK	v-crk sarcoma virus CT10 oncogene homolog (avian)	0.135
MEIS1	Meis homeobox 1	0.124
COL4A4	collagen, type IV, alpha 4	0.120	Human
PAX8	paired box 8	0.120
BMP7	bone morphogenetic protein 7	0.118	Human Mouse
CTNNA1	catenin (cadherin-associated protein), alpha 1, 102kDa	0.116
PKD2	polycystic kidney disease 2 (autosomal dominant)	0.115
COL5A1	collagen, type V, alpha 1	0.112
SMN1	survival of motor neuron 1, telomeric	0.111
PTPN11	protein tyrosine phosphatase, non-receptor type 11	0.110
ITGA5	integrin, alpha 5 (fibronectin receptor, alpha polypeptide)	0.109
PGF	placental growth factor	0.105	Mouse
EFNA1	ephrin-A1	0.102
FSTL1	follistatin-like 1	0.102
MEIS2	Meis homeobox 2	0.102
PARVA	parvin, alpha	0.101
FGF8	fibroblast growth factor 8 (androgen-induced)	0.098
GAB1	GRB2-associated binding protein 1	0.098
KDR	kinase insert domain receptor (a type III receptor tyrosine kinase)	0.095	Mouse
JDP2	Jun dimerization protein 2	0.088
BMPR2	bone morphogenetic protein receptor, type II (serine/threonine kinase)	0.079
DAB2	disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)	0.078
EGR1	early growth response 1	0.078	Human
FBXW11	F-box and WD repeat domain containing 11	0.077
TGFB2	transforming growth factor, beta 2	0.076
COL4A6	collagen, type IV, alpha 6	0.076	Human
TM4SF1	transmembrane 4 L six family member 1	0.076
CDH11	cadherin 11, type 2, OB-cadherin (osteoblast)	0.075
IQGAP1	IQ motif containing GTPase activating protein 1	0.073
PDGFC	platelet derived growth factor C	0.071
MYOD1	myogenic differentiation 1	0.070
AR	androgen receptor	0.070	Mouse
CHEK2	CHK2 checkpoint homolog (S. pombe)	0.069
STK3	serine/threonine kinase 3	0.066
PLAUR	plasminogen activator, urokinase receptor	0.065
MYC	v-myc myelocytomatosis viral oncogene homolog (avian)	0.065	Mouse
GSK3B	glycogen synthase kinase 3 beta	0.064
FGF4	fibroblast growth factor 4	0.063	Human
RB1	retinoblastoma 1	0.063
DUSP6	dual specificity phosphatase 6	0.063	Fly
HOXB5	homeobox B5	0.059
GATA4	GATA binding protein 4	0.059
ST14	suppression of tumorigenicity 14 (colon carcinoma)	0.058
BMPR1B	bone morphogenetic protein receptor, type IB	0.057
LUM	lumican	0.056
APC	adenomatous polyposis coli	0.054
TGFB3	transforming growth factor, beta 3	0.054
STC1	stanniocalcin 1	0.051
PTPRB	protein tyrosine phosphatase, receptor type, B	0.051
EGFR	epidermal growth factor receptor	0.051
MDM4	Mdm4 p53 binding protein homolog (mouse)	0.050
CD74	CD74 molecule, major histocompatibility complex, class II invariant chain	0.050
IGFBP5	insulin-like growth factor binding protein 5	0.048
PLAT	plasminogen activator, tissue	0.047	Human
WFIKKN2	WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2	0.046
IL8	interleukin 8	0.045
NOTCH3	notch 3	0.045
EGR3	early growth response 3	0.045	Human
PHLDA1	pleckstrin homology-like domain, family A, member 1	0.044
TNC	tenascin C	0.044
FOXD3	forkhead box D3	0.044
COL4A5	collagen, type IV, alpha 5	0.044	Human
ZFYVE9	zinc finger, FYVE domain containing 9	0.043
MSN	moesin	0.043
EDNRA	endothelin receptor type A	0.042	Mouse
CXCL12	chemokine (C-X-C motif) ligand 12	0.042	Mouse
SIM2	single-minded homolog 2 (Drosophila)	0.042
PKD1	polycystic kidney disease 1 (autosomal dominant)	0.042
CDH3	cadherin 3, type 1, P-cadherin (placental)	0.042
S100A4	S100 calcium binding protein A4	0.041
CCND1	cyclin D1	0.040
CLDN4	claudin 4	0.040
DMD	dystrophin	0.040
HNF1A	HNF1 homeobox A	0.040
TP73	tumor protein p73	0.039
INHBA	inhibin, beta A	0.038
MKL1	megakaryoblastic leukemia (translocation) 1	0.038
UTRN	utrophin	0.038
CTNND1	catenin (cadherin-associated protein), delta 1	0.038
PJA1	praja ring finger 1	0.037
FOXC2	forkhead box C2 (MFH-1, mesenchyme forkhead 1)	0.037
S100A2	S100 calcium binding protein A2	0.036
EGR2	early growth response 2	0.035	Human
LAMA4	laminin, alpha 4	0.035
SOX1	SRY (sex determining region Y)-box 1	0.035
CDH5	cadherin 5, type 2 (vascular endothelium)	0.035
CDC42	cell division cycle 42 (GTP binding protein, 25kDa)	0.034	Fly
CABLES1	Cdk5 and Abl enzyme substrate 1	0.034
MSX1	msh homeobox 1	0.033
DKK1	dickkopf homolog 1 (Xenopus laevis)	0.033
FOXF1	forkhead box F1	0.033
FOXF2	forkhead box F2	0.032	Human
TGFB1	transforming growth factor, beta 1	0.032	Mouse Rat
MEOX1	mesenchyme homeobox 1	0.032
PLXNB1	plexin B1	0.031
PPM1F	protein phosphatase, Mg2+/Mn2+ dependent, 1F	0.031
FOXA2	forkhead box A2	0.031	Mouse
CUEDC2	CUE domain containing 2	0.031
FGF7	fibroblast growth factor 7	0.030	Human
HMGA2	high mobility group AT-hook 2	0.030
VEGFC	vascular endothelial growth factor C	0.030
JAG2	jagged 2	0.029
TCF7L2	transcription factor 7-like 2 (T-cell specific, HMG-box)	0.029
SFRP1	secreted frizzled-related protein 1	0.028	Mouse
MYOCD	myocardin	0.028
POU5F1	POU class 5 homeobox 1	0.028
HIPK2	homeodomain interacting protein kinase 2	0.028
SHC2	SHC (Src homology 2 domain containing) transforming protein 2	0.027
LAMA5	laminin, alpha 5	0.026	Mouse
EDN1	endothelin 1	0.026	Mouse
WT1	Wilms tumor 1	0.026
NCOA6	nuclear receptor coactivator 6	0.025
HR	hairless homolog (mouse)	0.025
WNT1	wingless-type MMTV integration site family, member 1	0.025	Mouse Fly
TNFRSF1B	tumor necrosis factor receptor superfamily, member 1B	0.024
PECAM1	platelet/endothelial cell adhesion molecule	0.024
NRP2	neuropilin 2	0.024
SNAI1	snail homolog 1 (Drosophila)	0.024	Fly
PLEC	plectin	0.024	Fly
SLIT2	slit homolog 2 (Drosophila)	0.024
FGF3	fibroblast growth factor 3	0.024	Human
FYN	FYN oncogene related to SRC, FGR, YES	0.023
TOP1	topoisomerase (DNA) I	0.023
EPAS1	endothelial PAS domain protein 1	0.023
C3	complement component 3	0.023
SMAD7	SMAD family member 7	0.023
PDGFB	platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)	0.022	Mouse
CYR61	cysteine-rich, angiogenic inducer, 61	0.022
CITED2	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2	0.022
IL6R	interleukin 6 receptor	0.022
CSF1	colony stimulating factor 1 (macrophage)	0.022	Mouse
APOH	apolipoprotein H (beta-2-glycoprotein I)	0.022
A2M	alpha-2-macroglobulin	0.022
PLCG1	phospholipase C, gamma 1	0.022
HAS2	hyaluronan synthase 2	0.021
CAV1	caveolin 1, caveolae protein, 22kDa	0.021
FZD1	frizzled homolog 1 (Drosophila)	0.021
PTGS2	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)	0.021
IGFBP3	insulin-like growth factor binding protein 3	0.021
ROD1	ROD1 regulator of differentiation 1 (S. pombe)	0.021
SPDEF	SAM pointed domain containing ets transcription factor	0.021
COL7A1	collagen, type VII, alpha 1	0.020
PGR	progesterone receptor	0.020	Mouse
MCL1	myeloid cell leukemia sequence 1 (BCL2-related)	0.020
NCOA2	nuclear receptor coactivator 2	0.020
PTGIS	prostaglandin I2 (prostacyclin) synthase	0.020
SATB2	SATB homeobox 2	0.020
FZD7	frizzled homolog 7 (Drosophila)	0.020
PRRX1	paired related homeobox 1	0.020
RET	ret proto-oncogene	0.020
WFIKKN1	WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1	0.020
PLAU	plasminogen activator, urokinase	0.019	Human
VDR	vitamin D (1,25- dihydroxyvitamin D3) receptor	0.019	Mouse
TGFA	transforming growth factor, alpha	0.019
ENG	endoglin	0.019	Mouse
BCL2L11	BCL2-like 11 (apoptosis facilitator)	0.019
SH3RF3	SH3 domain containing ring finger 3	0.019
COL1A2	collagen, type I, alpha 2	0.019
SFN	stratifin	0.019
FOXC1	forkhead box C1	0.019
XIAP	X-linked inhibitor of apoptosis	0.019
RNR2	l-rRNA	0.018
PAX7	paired box 7	0.018
PKP3	plakophilin 3	0.018
FST	follistatin	0.018
TGFBR1	transforming growth factor, beta receptor 1	0.018
CCL2	chemokine (C-C motif) ligand 2	0.018
INHBB	inhibin, beta B	0.018
F3	coagulation factor III (thromboplastin, tissue factor)	0.018
MET	met proto-oncogene (hepatocyte growth factor receptor)	0.017
TAOK1	TAO kinase 1	0.017
PPARA	peroxisome proliferator-activated receptor alpha	0.017
PDGFRB	platelet-derived growth factor receptor, beta polypeptide	0.017
SCYL2	SCY1-like 2 (S. cerevisiae)	0.017
LMX1B	LIM homeobox transcription factor 1, beta	0.017
IL6	interleukin 6 (interferon, beta 2)	0.017	Mouse
BCL3	B-cell CLL/lymphoma 3	0.017
CLDN1	claudin 1	0.017
MAGED2	melanoma antigen family D, 2	0.016
CLDN7	claudin 7	0.016
LBX1	ladybird homeobox 1	0.016
EP300	E1A binding protein p300	0.016
EFEMP1	EGF containing fibulin-like extracellular matrix protein 1	0.016
CHEK1	CHK1 checkpoint homolog (S. pombe)	0.016
ITGA3	integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)	0.016
DAXX	death-domain associated protein	0.016
NOTCH1	notch 1	0.016	Mouse
CARS	cysteinyl-tRNA synthetase	0.016
COL6A1	collagen, type VI, alpha 1	0.016
MYOG	myogenin (myogenic factor 4)	0.016
ICAM1	intercellular adhesion molecule 1	0.016
DPP4	dipeptidyl-peptidase 4	0.016
TBX1	T-box 1	0.015
RUNX1T1	runt-related transcription factor 1; translocated to, 1 (cyclin D-related)	0.015
HBEGF	heparin-binding EGF-like growth factor	0.015
MAPK8	mitogen-activated protein kinase 8	0.015
IL1B	interleukin 1, beta	0.015
KRT6C	keratin 6C	0.015
ESR2	estrogen receptor 2 (ER beta)	0.015
SORBS3	sorbin and SH3 domain containing 3	0.015
MYST2	MYST histone acetyltransferase 2	0.015
SPARC	secreted protein, acidic, cysteine-rich (osteonectin)	0.015
DDX17	DEAD (Asp-Glu-Ala-Asp) box polypeptide 17	0.015
WNT2	wingless-type MMTV integration site family member 2	0.015
ARNT	aryl hydrocarbon receptor nuclear translocator	0.015
TFAP2A	transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)	0.015
CACNA1G	calcium channel, voltage-dependent, T type, alpha 1G subunit	0.014
SOCS1	suppressor of cytokine signaling 1	0.014
NTRK2	neurotrophic tyrosine kinase, receptor, type 2	0.014
ALX4	ALX homeobox 4	0.014
HSPG2	heparan sulfate proteoglycan 2	0.014
SEMA4A	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A	0.014
YY1	YY1 transcription factor	0.014
SALL2	sal-like 2 (Drosophila)	0.014
SHB	Src homology 2 domain containing adaptor protein B	0.014
ITGA8	integrin, alpha 8	0.014
CRKL	v-crk sarcoma virus CT10 oncogene homolog (avian)-like	0.014
FOXE1	forkhead box E1 (thyroid transcription factor 2)	0.014
TP53	tumor protein p53	0.014
YARS	tyrosyl-tRNA synthetase	0.014
FGF18	fibroblast growth factor 18	0.014
TCF7L1	transcription factor 7-like 1 (T-cell specific, HMG-box)	0.014
WNT3A	wingless-type MMTV integration site family, member 3A	0.014
LATS2	LATS, large tumor suppressor, homolog 2 (Drosophila)	0.014
LIF	leukemia inhibitory factor (cholinergic differentiation factor)	0.013
RBPJ	recombination signal binding protein for immunoglobulin kappa J region	0.013
TWSG1	twisted gastrulation homolog 1 (Drosophila)	0.013
NID1	nidogen 1	0.013
TNRC6B	trinucleotide repeat containing 6B	0.013
ZBTB16	zinc finger and BTB domain containing 16	0.013
EYA2	eyes absent homolog 2 (Drosophila)	0.013
FGFR3	fibroblast growth factor receptor 3	0.013	Fly
GDNF	glial cell derived neurotrophic factor	0.013
NKX3-2	NK3 homeobox 2	0.013	Human
HOXB13	homeobox B13	0.013	Mouse
GABPA	GA binding protein transcription factor, alpha subunit 60kDa	0.013
NCOA1	nuclear receptor coactivator 1	0.013
CXCL3	chemokine (C-X-C motif) ligand 3	0.013
MNX1	motor neuron and pancreas homeobox 1	0.013
CXCL1	chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)	0.013
AKT1	v-akt murine thymoma viral oncogene homolog 1	0.013
RPS6KA6	ribosomal protein S6 kinase, 90kDa, polypeptide 6	0.013
GPC3	glypican 3	0.012
PTHLH	parathyroid hormone-like hormone	0.012
NOG	noggin	0.012	Mouse
BIK	BCL2-interacting killer (apoptosis-inducing)	0.012
LTBP2	latent transforming growth factor beta binding protein 2	0.012
LMO4	LIM domain only 4	0.012
NEUROG2	neurogenin 2	0.012
CALCA	calcitonin-related polypeptide alpha	0.012
NCK2	NCK adaptor protein 2	0.012
CSF2	colony stimulating factor 2 (granulocyte-macrophage)	0.012
NFIB	nuclear factor I/B	0.012
FZD8	frizzled homolog 8 (Drosophila)	0.012
THBS2	thrombospondin 2	0.012
RNF144B	ring finger protein 144B	0.012
HOXD13	homeobox D13	0.012	Mouse
FOXA1	forkhead box A1	0.012	Mouse
NR4A3	nuclear receptor subfamily 4, group A, member 3	0.012
THBD	thrombomodulin	0.012
CDH6	cadherin 6, type 2, K-cadherin (fetal kidney)	0.012
CXCL2	chemokine (C-X-C motif) ligand 2	0.012
ASAP1	ArfGAP with SH3 domain, ankyrin repeat and PH domain 1	0.012
HOXD10	homeobox D10	0.011
SP1	Sp1 transcription factor	0.011
KRT5	keratin 5	0.011
EFNB2	ephrin-B2	0.011
CD34	CD34 molecule	0.011
BCAM	basal cell adhesion molecule (Lutheran blood group)	0.011
MAX	MYC associated factor X	0.011
LAMC1	laminin, gamma 1 (formerly LAMB2)	0.011
LAMC2	laminin, gamma 2	0.011
AGRN	agrin	0.011
PAX6	paired box 6	0.011
FNDC3B	fibronectin type III domain containing 3B	0.011
PPP1CC	protein phosphatase 1, catalytic subunit, gamma isozyme	0.011
RARG	retinoic acid receptor, gamma	0.011
NR5A2	nuclear receptor subfamily 5, group A, member 2	0.011
NEDD4	neural precursor cell expressed, developmentally down-regulated 4	0.011
TNRC6A	trinucleotide repeat containing 6A	0.011
ERG	v-ets erythroblastosis virus E26 oncogene homolog (avian)	0.011
SIX2	SIX homeobox 2	0.011	Mouse
NKX3-1	NK3 homeobox 1	0.011	Mouse
LIMK1	LIM domain kinase 1	0.011
TNFRSF10B	tumor necrosis factor receptor superfamily, member 10b	0.011
SMAD1	SMAD family member 1	0.011
CDH2	cadherin 2, type 1, N-cadherin (neuronal)	0.011
TNFRSF1A	tumor necrosis factor receptor superfamily, member 1A	0.011
VCAM1	vascular cell adhesion molecule 1	0.011
TWIST1	twist homolog 1 (Drosophila)	0.011
EFNA2	ephrin-A2	0.011
RASSF2	Ras association (RalGDS/AF-6) domain family member 2	0.010
SOX9	SRY (sex determining region Y)-box 9	0.010	Mouse
OSMR	oncostatin M receptor	0.010
AMMECR1	Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1	0.010
IPO8	importin 8	0.010
CXCR4	chemokine (C-X-C motif) receptor 4	0.010	Mouse
ONECUT1	one cut homeobox 1	0.010
CAPRIN2	caprin family member 2	0.010
LAPTM5	lysosomal protein transmembrane 5	0.010
FZD10	frizzled homolog 10 (Drosophila)	0.010
FRS2	fibroblast growth factor receptor substrate 2	0.010	Mouse
MKL2	MKL/myocardin-like 2	0.010
TGFBI	transforming growth factor, beta-induced, 68kDa	0.010
TFAP2C	transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)	0.010	Mouse