|
|
regulation of macrophage differentiation
|
GO:0045649 |
9 |
1.000
|
Human |
|
|
cellular modified amino acid catabolic process
|
GO:0042219 |
4 |
0.999
|
|
|
|
positive regulation of cell cycle arrest
|
GO:0071158 |
23 |
0.999
|
Human |
|
|
trail activated apoptotic signaling pathway
|
GO:0036462 |
4 |
0.999
|
Human |
|
|
regulation of cell cycle arrest
|
GO:0071156 |
36 |
0.999
|
Human |
|
|
intracellular signal transduction involved in g1 dna damage checkpoint
|
GO:1902400 |
10 |
0.998
|
Human |
|
|
positive regulation of myeloid leukocyte differentiation
|
GO:0002763 |
24 |
0.998
|
Human |
|
|
macrophage differentiation
|
GO:0030225 |
11 |
0.997
|
Human |
|
|
signal transduction involved in mitotic g1 dna damage checkpoint
|
GO:0072431 |
10 |
0.996
|
Human |
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
380 |
0.994
|
Human Mouse |
|
|
cell type specific apoptotic process
|
GO:0097285 |
125 |
0.994
|
Mouse Rat |
|
|
positive regulation of macrophage differentiation
|
GO:0045651 |
7 |
0.993
|
Human |
|
|
dna damage response signal transduction by p53 class mediator resulting in cell cycle arrest
|
GO:0006977 |
9 |
0.992
|
Human |
|
|
mitotic g1 dna damage checkpoint
|
GO:0031571 |
17 |
0.991
|
Human |
|
|
regulation of peptidase activity
|
GO:0052547 |
180 |
0.991
|
Human |
|
|
zymogen activation
|
GO:0031638 |
70 |
0.991
|
Human |
|
|
activation of cysteine type endopeptidase activity
|
GO:0097202 |
57 |
0.988
|
Human |
|
|
cellular response to mechanical stimulus
|
GO:0071260 |
39 |
0.986
|
Human |
|
|
dna damage response signal transduction by p53 class mediator
|
GO:0030330 |
44 |
0.983
|
Human |
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.982
|
Human Zebrafish Mouse Rat |
|
|
protein processing
|
GO:0016485 |
226 |
0.981
|
Human Mouse |
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
70 |
0.981
|
|
|
|
positive regulation of peptidase activity
|
GO:0010952 |
88 |
0.981
|
Human |
|
|
negative regulation of g1 s transition of mitotic cell cycle
|
GO:2000134 |
29 |
0.980
|
Human |
|
|
positive regulation of neuron apoptotic process
|
GO:0043525 |
8 |
0.980
|
Mouse Rat |
|
|
mitotic cell cycle phase transition
|
GO:0044772 |
162 |
0.975
|
Human |
|
|
g1 dna damage checkpoint
|
GO:0044783 |
18 |
0.974
|
Human |
|
|
signal transduction involved in mitotic dna integrity checkpoint
|
GO:1902403 |
13 |
0.973
|
Human |
|
|
signal transduction involved in mitotic cell cycle checkpoint
|
GO:0072413 |
13 |
0.972
|
Human |
|
|
erythrocyte differentiation
|
GO:0030218 |
28 |
0.970
|
|
|
|
dna integrity checkpoint
|
GO:0031570 |
71 |
0.969
|
Human |
|
|
cellular response to abiotic stimulus
|
GO:0071214 |
117 |
0.967
|
Human |
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.966
|
|
|
|
signal transduction involved in cell cycle checkpoint
|
GO:0072395 |
16 |
0.964
|
Human |
|
|
regulation of cell cycle g1 s phase transition
|
GO:1902806 |
42 |
0.963
|
Human |
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
189 |
0.962
|
Human |
|
|
positive regulation of proteolysis
|
GO:0045862 |
142 |
0.960
|
Human |
|
|
negative regulation of cell cycle phase transition
|
GO:1901988 |
89 |
0.960
|
Human |
|
|
protein maturation
|
GO:0051604 |
233 |
0.959
|
Human Mouse |
|
|
cell cycle arrest
|
GO:0007050 |
71 |
0.958
|
Human |
|
|
substantia nigra development
|
GO:0021762 |
45 |
0.956
|
Human |
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.953
|
|
|
|
neuron apoptotic process
|
GO:0051402 |
39 |
0.944
|
Mouse Rat |
|
|
response to cytokine
|
GO:0034097 |
232 |
0.944
|
Human |
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.944
|
Human |
|
|
regulation of endopeptidase activity
|
GO:0052548 |
170 |
0.942
|
Human |
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.941
|
Human Mouse |
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.941
|
Human |
|
|
positive regulation of cysteine type endopeptidase activity
|
GO:2001056 |
79 |
0.941
|
Human |
|
|
positive regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043280 |
69 |
0.937
|
|
|
|
g1 s transition of mitotic cell cycle
|
GO:0000082 |
78 |
0.936
|
Human |
|
|
regulation of i kappab kinase nf kappab signaling
|
GO:0043122 |
162 |
0.936
|
Human |
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.935
|
Human Mouse |
|
|
regulation of myeloid cell differentiation
|
GO:0045637 |
81 |
0.930
|
Human |
|
|
signal transduction involved in dna damage checkpoint
|
GO:0072422 |
15 |
0.930
|
Human |
|
|
positive regulation of cell cycle
|
GO:0045787 |
140 |
0.927
|
Human |
|
|
signal transduction involved in mitotic dna damage checkpoint
|
GO:1902402 |
13 |
0.920
|
Human |
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.916
|
Human |
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.916
|
Human Mouse |
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.916
|
Human Zebrafish Mouse Rat |
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
119 |
0.914
|
Human Mouse |
|
|
cell cycle checkpoint
|
GO:0000075 |
117 |
0.911
|
Human |
|
|
kidney development
|
GO:0001822 |
53 |
0.911
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.910
|
Human |
|
|
carboxylic acid catabolic process
|
GO:0046395 |
71 |
0.905
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.904
|
Human Zebrafish Mouse Rat |
|
|
dna damage checkpoint
|
GO:0000077 |
68 |
0.901
|
Human |
|
|
positive regulation of i kappab kinase nf kappab signaling
|
GO:0043123 |
132 |
0.893
|
Human |
|
|
execution phase of apoptosis
|
GO:0097194 |
32 |
0.891
|
|
|
|
extrinsic apoptotic signaling pathway via death domain receptors
|
GO:0008625 |
42 |
0.891
|
Human Mouse |
|
|
small molecule catabolic process
|
GO:0044282 |
92 |
0.890
|
|
|
|
midbrain development
|
GO:0030901 |
45 |
0.888
|
Human |
|
|
glial cell apoptotic process
|
GO:0034349 |
7 |
0.877
|
Mouse Rat |
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
147 |
0.871
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.869
|
Human Mouse Rat |
|
|
response to estradiol
|
GO:0032355 |
23 |
0.867
|
Rat |
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
166 |
0.867
|
Human |
|
|
protein oligomerization
|
GO:0051259 |
173 |
0.866
|
|
|
|
regulation of cysteine type endopeptidase activity
|
GO:2000116 |
127 |
0.866
|
Human |
|
|
hemopoiesis
|
GO:0030097 |
180 |
0.861
|
|
|
|
regulation of neuron apoptotic process
|
GO:0043523 |
35 |
0.852
|
Mouse Rat |
|
|
immune system development
|
GO:0002520 |
195 |
0.851
|
|
|
|
cellular response to uv
|
GO:0034644 |
32 |
0.845
|
Human |
|
|
negative regulation of mitotic cell cycle
|
GO:0045930 |
102 |
0.843
|
Human |
|
|
negative regulation of mitotic cell cycle phase transition
|
GO:1901991 |
85 |
0.837
|
Human |
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
244 |
0.837
|
Human |
|
|
leukocyte differentiation
|
GO:0002521 |
98 |
0.833
|
Human |
|
|
cellular protein catabolic process
|
GO:0044257 |
261 |
0.833
|
Human |
|
|
signal transduction in response to dna damage
|
GO:0042770 |
57 |
0.832
|
Human |
|
|
response to hormone
|
GO:0009725 |
175 |
0.832
|
Rat |
|
|
cellular modified amino acid metabolic process
|
GO:0006575 |
64 |
0.832
|
|
|
|
cellular response to external stimulus
|
GO:0071496 |
111 |
0.832
|
Human |
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.830
|
Zebrafish |
|
|
cell cycle g1 s phase transition
|
GO:0044843 |
80 |
0.828
|
Human |
|
|
response to radiation
|
GO:0009314 |
151 |
0.824
|
Human Mouse Rat |
|
|
positive regulation of myeloid cell differentiation
|
GO:0045639 |
39 |
0.821
|
Human |
|
|
positive regulation of neuron death
|
GO:1901216 |
14 |
0.812
|
Mouse Rat |
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.811
|
Human |
|
|
negative regulation of cell cycle g1 s phase transition
|
GO:1902807 |
29 |
0.810
|
Human |
|
|
mitotic dna damage checkpoint
|
GO:0044773 |
28 |
0.810
|
Human |
|
|
negative regulation of cell cycle process
|
GO:0010948 |
121 |
0.806
|
Human |
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.800
|
Human |
|
|
homeostasis of number of cells
|
GO:0048872 |
40 |
0.799
|
|
|
|
activation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0006919 |
49 |
0.797
|
|
|
|
positive regulation of immune system process
|
GO:0002684 |
283 |
0.788
|
Human |
|
|
neural tube formation
|
GO:0001841 |
3 |
0.777
|
|
|
|
response to mechanical stimulus
|
GO:0009612 |
51 |
0.769
|
Human |
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
175 |
0.769
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.764
|
|
|
|
regulation of execution phase of apoptosis
|
GO:1900117 |
11 |
0.760
|
Mouse |
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
60 |
0.752
|
Human |
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.749
|
|
|
|
positive regulation of cell cycle process
|
GO:0090068 |
106 |
0.743
|
Human |
|
|
urogenital system development
|
GO:0001655 |
65 |
0.730
|
|
|
|
epithelium development
|
GO:0060429 |
227 |
0.726
|
Human Mouse |
|
|
cell cycle phase transition
|
GO:0044770 |
173 |
0.715
|
Human |
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.710
|
|
|
|
regulation of response to dna damage stimulus
|
GO:2001020 |
94 |
0.703
|
Human |
|
|
response to estrogen
|
GO:0043627 |
47 |
0.702
|
Rat |
|
|
negative regulation of humoral immune response
|
GO:0002921 |
7 |
0.686
|
|
|
|
tube morphogenesis
|
GO:0035239 |
95 |
0.671
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.654
|
|
|
|
positive regulation of endopeptidase activity
|
GO:0010950 |
84 |
0.654
|
Human |
|
|
response to lipopolysaccharide
|
GO:0032496 |
70 |
0.653
|
Rat |
|
|
sulfur compound metabolic process
|
GO:0006790 |
101 |
0.644
|
|
|
|
primary neural tube formation
|
GO:0014020 |
3 |
0.643
|
|
|
|
negative regulation of i kappab kinase nf kappab signaling
|
GO:0043124 |
32 |
0.628
|
Human |
|
|
protein homooligomerization
|
GO:0051260 |
100 |
0.628
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.626
|
|
|
|
regulation of dna metabolic process
|
GO:0051052 |
153 |
0.625
|
Mouse |
|
|
brain development
|
GO:0007420 |
97 |
0.625
|
Human Rat |
|
|
response to tumor necrosis factor
|
GO:0034612 |
76 |
0.624
|
Human |
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043281 |
116 |
0.606
|
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
127 |
0.594
|
Human Mouse |
|
|
coenzyme metabolic process
|
GO:0006732 |
65 |
0.593
|
|
|
|
head development
|
GO:0060322 |
108 |
0.591
|
Human Rat |
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
61 |
0.587
|
Human |
|
|
response to light stimulus
|
GO:0009416 |
87 |
0.580
|
Human Mouse |
|
|
lymphocyte apoptotic process
|
GO:0070227 |
20 |
0.546
|
|
|
|
leukocyte apoptotic process
|
GO:0071887 |
31 |
0.544
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.543
|
Human Rat |
|
|
response to gamma radiation
|
GO:0010332 |
14 |
0.537
|
|
|
|
apoptotic mitochondrial changes
|
GO:0008637 |
57 |
0.530
|
Mouse |
|
|
regulation of cell cycle phase transition
|
GO:1901987 |
126 |
0.527
|
Human |
|
|
central nervous system development
|
GO:0007417 |
123 |
0.513
|
Human Rat |
|
|
response to metal ion
|
GO:0010038 |
84 |
0.512
|
Rat |
|
|
protein heterooligomerization
|
GO:0051291 |
16 |
0.509
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.505
|
Human |
|
|
cellular amino acid catabolic process
|
GO:0009063 |
31 |
0.504
|
|
|
|
neural nucleus development
|
GO:0048857 |
47 |
0.500
|
Human |
|
|
neuron death
|
GO:0070997 |
65 |
0.499
|
Mouse Rat |
|
|
regulation of lymphocyte apoptotic process
|
GO:0070228 |
15 |
0.489
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.486
|
Human |
|
|
myeloid cell homeostasis
|
GO:0002262 |
34 |
0.482
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
117 |
0.481
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.479
|
Human |
|
|
cellular response to hormone stimulus
|
GO:0032870 |
125 |
0.454
|
|
|
|
response to external biotic stimulus
|
GO:0043207 |
261 |
0.449
|
Rat |
|
|
cellular response to glucocorticoid stimulus
|
GO:0071385 |
4 |
0.448
|
|
|
|
apoptotic nuclear changes
|
GO:0030262 |
13 |
0.438
|
Mouse |
|
|
mitotic g1 s transition checkpoint
|
GO:0044819 |
17 |
0.438
|
Human |
|
|
renal system development
|
GO:0072001 |
63 |
0.437
|
|
|
|
signal transduction involved in dna integrity checkpoint
|
GO:0072401 |
15 |
0.436
|
Human |
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.432
|
Human |
|
|
erythrocyte homeostasis
|
GO:0034101 |
31 |
0.432
|
|
|
|
cellular response to dexamethasone stimulus
|
GO:0071549 |
1 |
0.429
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.420
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
136 |
0.420
|
Mouse |
|
|
renal system process
|
GO:0003014 |
25 |
0.403
|
|
|
|
tube development
|
GO:0035295 |
125 |
0.394
|
|
|
|
response to steroid hormone
|
GO:0048545 |
80 |
0.385
|
Rat |
|
|
response to lipid
|
GO:0033993 |
206 |
0.383
|
Zebrafish Rat |
|
|
negative regulation of peptidase activity
|
GO:0010466 |
91 |
0.376
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.373
|
|
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
85 |
0.369
|
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
209 |
0.364
|
|
|
|
anatomical structure homeostasis
|
GO:0060249 |
100 |
0.363
|
|
|
|
signal transduction by p53 class mediator
|
GO:0072331 |
72 |
0.356
|
Human |
|
|
cellular response to lipid
|
GO:0071396 |
127 |
0.344
|
Zebrafish |
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.341
|
Rat |
|
|
response to inorganic substance
|
GO:0010035 |
127 |
0.333
|
Rat |
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.330
|
Zebrafish Rat |
|
|
release of cytochrome c from mitochondria
|
GO:0001836 |
35 |
0.325
|
Mouse |
|
|
innate immune response
|
GO:0045087 |
178 |
0.319
|
|
|
|
regulation of mitotic cell cycle phase transition
|
GO:1901990 |
118 |
0.317
|
Human |
|
|
response to other organism
|
GO:0051707 |
261 |
0.303
|
Rat |
|
|
alpha amino acid catabolic process
|
GO:1901606 |
26 |
0.299
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.294
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.286
|
|
|
|
response to nitrogen compound
|
GO:1901698 |
184 |
0.283
|
Rat |
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.281
|
|
|
|
tube closure
|
GO:0060606 |
3 |
0.277
|
|
|
|
regulation of protein monoubiquitination
|
GO:1902525 |
1 |
0.277
|
|
|
|
cellular component disassembly involved in execution phase of apoptosis
|
GO:0006921 |
13 |
0.272
|
Mouse |
|
|
spermatid development
|
GO:0007286 |
4 |
0.270
|
|
|
|
forebrain development
|
GO:0030900 |
26 |
0.266
|
Rat |
|
|
defense response
|
GO:0006952 |
315 |
0.258
|
|
|
|
chemical homeostasis
|
GO:0048878 |
306 |
0.258
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.258
|
|
|
|
programmed necrotic cell death
|
GO:0097300 |
18 |
0.255
|
|
|
|
regulation of necroptotic process
|
GO:0060544 |
7 |
0.252
|
|
|
|
humoral immune response
|
GO:0006959 |
49 |
0.246
|
|
|
|
negative regulation of immune response
|
GO:0050777 |
40 |
0.236
|
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.231
|
|
|
|
cellular homeostasis
|
GO:0019725 |
196 |
0.225
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
342 |
0.220
|
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
97 |
0.218
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.218
|
|
|
|
mitotic dna integrity checkpoint
|
GO:0044774 |
30 |
0.218
|
Human |
|
|
apoptotic dna fragmentation
|
GO:0006309 |
6 |
0.215
|
Mouse |
|
|
regulation of myeloid leukocyte differentiation
|
GO:0002761 |
39 |
0.212
|
Human |
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.208
|
|
|
|
regulation of leukocyte apoptotic process
|
GO:2000106 |
25 |
0.204
|
|
|
|
epithelial tube morphogenesis
|
GO:0060562 |
38 |
0.198
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.195
|
Mouse |
|
|
tissue morphogenesis
|
GO:0048729 |
96 |
0.192
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.192
|
Mouse |
|
|
transmembrane transport
|
GO:0055085 |
399 |
0.192
|
|
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
108 |
0.191
|
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
206 |
0.183
|
|
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.176
|
|
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.175
|
|
|
|
response to ketone
|
GO:1901654 |
19 |
0.174
|
|
|
|
mitochondrion organization
|
GO:0007005 |
156 |
0.169
|
Mouse |
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.168
|
Mouse |
|
|
positive regulation of extrinsic apoptotic signaling pathway
|
GO:2001238 |
26 |
0.160
|
|
|
|
neural tube closure
|
GO:0001843 |
3 |
0.159
|
|
|
|
neural tube development
|
GO:0021915 |
9 |
0.159
|
|
|
|
mitotic cell cycle checkpoint
|
GO:0007093 |
68 |
0.157
|
Human |
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
4 |
0.155
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
156 |
0.152
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
207 |
0.149
|
|
|
|
regulation of glial cell apoptotic process
|
GO:0034350 |
6 |
0.149
|
|
|
|
organ morphogenesis
|
GO:0009887 |
147 |
0.142
|
|
|
|
embryonic morphogenesis
|
GO:0048598 |
85 |
0.140
|
|
|
|
ion transmembrane transport
|
GO:0034220 |
338 |
0.137
|
|
|
|
regulation of neuron death
|
GO:1901214 |
56 |
0.136
|
Mouse Rat |
|
|
protein ubiquitination
|
GO:0016567 |
314 |
0.131
|
|
|
|
cardiac ventricle formation
|
GO:0003211 |
2 |
0.129
|
|
|
|
intrinsic apoptotic signaling pathway in response to dna damage
|
GO:0008630 |
50 |
0.127
|
Human |
|
|
negative regulation of extrinsic apoptotic signaling pathway
|
GO:2001237 |
52 |
0.124
|
|
|
|
negative regulation of proteolysis
|
GO:0045861 |
132 |
0.123
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.123
|
Human |
|
|
positive regulation of gliogenesis
|
GO:0014015 |
4 |
0.121
|
|
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.121
|
|
|
|
lipid metabolic process
|
GO:0006629 |
381 |
0.120
|
|
|
|
cell projection organization
|
GO:0030030 |
252 |
0.118
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.117
|
|
|
|
neurogenesis
|
GO:0022008 |
169 |
0.117
|
Rat |
|
|
cellular response to steroid hormone stimulus
|
GO:0071383 |
37 |
0.116
|
|
|
|
sensory organ development
|
GO:0007423 |
52 |
0.116
|
|
|
|
response to antibiotic
|
GO:0046677 |
15 |
0.115
|
Zebrafish Rat |
|
|
negative regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043154 |
46 |
0.113
|
|
|
|
response to bacterium
|
GO:0009617 |
144 |
0.111
|
Rat |
|
|
cell projection morphogenesis
|
GO:0048858 |
129 |
0.110
|
|
|
|
cardiac right ventricle morphogenesis
|
GO:0003215 |
3 |
0.110
|
|
|
|
canonical wnt signaling pathway
|
GO:0060070 |
116 |
0.108
|
|
|
|
somatic stem cell division
|
GO:0048103 |
1 |
0.108
|
|
|
|
response to oxidative stress
|
GO:0006979 |
121 |
0.108
|
Mouse Rat |
|
|
cellular response to muramyl dipeptide
|
GO:0071225 |
3 |
0.104
|
|
|
|
regulation of protein linear polyubiquitination
|
GO:1902528 |
2 |
0.104
|
|
|
|
lipid homeostasis
|
GO:0055088 |
39 |
0.103
|
|
|
|
proteasomal protein catabolic process
|
GO:0010498 |
176 |
0.103
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.101
|
|
|
|
regulation of protein processing
|
GO:0070613 |
150 |
0.097
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
170 |
0.096
|
|
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
212 |
0.096
|
|
|
|
secondary metabolic process
|
GO:0019748 |
17 |
0.095
|
|
|
|
negative regulation of t cell apoptotic process
|
GO:0070233 |
4 |
0.094
|
|
|
|
response to uv
|
GO:0009411 |
73 |
0.094
|
Human Mouse |
|
|
positive regulation of protein polyubiquitination
|
GO:1902916 |
3 |
0.094
|
|
|
|
response to dexamethasone
|
GO:0071548 |
1 |
0.094
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.094
|
|
|
|
regulation of canonical wnt signaling pathway
|
GO:0060828 |
88 |
0.093
|
|
|
|
neuron cellular homeostasis
|
GO:0070050 |
3 |
0.092
|
|
|
|
positive regulation of leukocyte differentiation
|
GO:1902107 |
37 |
0.092
|
Human |
|
|
regulation of protein ubiquitination
|
GO:0031396 |
95 |
0.090
|
|
|
|
response to toxic substance
|
GO:0009636 |
37 |
0.089
|
Zebrafish Rat |
|
|
epithelial cell proliferation
|
GO:0050673 |
128 |
0.089
|
|
|
|
regulation of branching involved in ureteric bud morphogenesis
|
GO:0090189 |
3 |
0.088
|
|
|
|
oxidation reduction process
|
GO:0055114 |
396 |
0.088
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.088
|
|
|
|
positive regulation of peptidyl tyrosine phosphorylation
|
GO:0050731 |
85 |
0.087
|
|
|
|
regulation of transmembrane transporter activity
|
GO:0022898 |
74 |
0.087
|
|
|
|
cell division
|
GO:0051301 |
168 |
0.087
|
|
|
|
neuron development
|
GO:0048666 |
113 |
0.086
|
|
|
|
cellular response to radiation
|
GO:0071478 |
65 |
0.086
|
Human |
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.085
|
|
|
|
dna repair
|
GO:0006281 |
198 |
0.084
|
|
|
|
cellular response to corticosteroid stimulus
|
GO:0071384 |
5 |
0.081
|
|
|
|
cell cell signaling
|
GO:0007267 |
155 |
0.080
|
|
|
|
cardiac right ventricle formation
|
GO:0003219 |
1 |
0.080
|
|
|
|
aortic valve development
|
GO:0003176 |
3 |
0.079
|
|
|
|
regulation of cyclin dependent protein serine threonine kinase activity
|
GO:0000079 |
36 |
0.079
|
Mouse |
|
|
hair follicle morphogenesis
|
GO:0031069 |
2 |
0.079
|
|
|
|
negative regulation of endopeptidase activity
|
GO:0010951 |
84 |
0.078
|
|
|
|
response to extracellular stimulus
|
GO:0009991 |
85 |
0.077
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.075
|
|
|
|
peptidyl serine phosphorylation
|
GO:0018105 |
101 |
0.074
|
|
|
|
single organism carbohydrate metabolic process
|
GO:0044723 |
193 |
0.074
|
|
|
|
regulation of dna catabolic process
|
GO:1903624 |
7 |
0.073
|
Mouse |
|
|
regulation of neural precursor cell proliferation
|
GO:2000177 |
4 |
0.073
|
|
|
|
anion transport
|
GO:0006820 |
161 |
0.072
|
|
|
|
response to glucocorticoid
|
GO:0051384 |
13 |
0.072
|
Rat |
|
|
positive regulation of canonical wnt signaling pathway
|
GO:0090263 |
33 |
0.072
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.071
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.071
|
|
|
|
peptidyl serine modification
|
GO:0018209 |
106 |
0.070
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.069
|
|
|
|
cellular carbohydrate biosynthetic process
|
GO:0034637 |
21 |
0.069
|
|
|
|
regulation of extrinsic apoptotic signaling pathway in absence of ligand
|
GO:2001239 |
20 |
0.069
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.068
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
170 |
0.067
|
|
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
144 |
0.067
|
|
|
|
negative regulation of protein maturation
|
GO:1903318 |
142 |
0.067
|
|
|
|
inflammatory response
|
GO:0006954 |
79 |
0.067
|
|
|
|
biological adhesion
|
GO:0022610 |
331 |
0.067
|
|
|
|
peripheral nervous system development
|
GO:0007422 |
2 |
0.066
|
|
|
|
motor neuron axon guidance
|
GO:0008045 |
2 |
0.065
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.064
|
Mouse |
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
182 |
0.064
|
|
|
|
regulation of transmembrane transport
|
GO:0034762 |
139 |
0.064
|
|
|
|
cell part morphogenesis
|
GO:0032990 |
137 |
0.064
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
92 |
0.063
|
|
|
|
regeneration
|
GO:0031099 |
4 |
0.063
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.062
|
|
|
|
negative regulation of cysteine type endopeptidase activity
|
GO:2000117 |
48 |
0.062
|
|
|
|
natural killer cell apoptotic process
|
GO:0070246 |
1 |
0.062
|
|
|
|
pigment metabolic process
|
GO:0042440 |
16 |
0.062
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
104 |
0.061
|
|
|
|
phospholipid metabolic process
|
GO:0006644 |
99 |
0.061
|
|
|
|
regulation of g1 s transition of mitotic cell cycle
|
GO:2000045 |
40 |
0.061
|
Human |
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.061
|
Mouse |
|
|
necrotic cell death
|
GO:0070265 |
21 |
0.060
|
|
|
|
peptidyl threonine phosphorylation
|
GO:0018107 |
41 |
0.060
|
|
|
|
response to molecule of bacterial origin
|
GO:0002237 |
82 |
0.060
|
Rat |
|
|
t cell homeostasis
|
GO:0043029 |
3 |
0.059
|
Mouse |
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.059
|
|
|
|
cardiac chamber formation
|
GO:0003207 |
2 |
0.059
|
|
|
|
chordate embryonic development
|
GO:0043009 |
34 |
0.058
|
|
|
|
regulation of protein maturation
|
GO:1903317 |
150 |
0.057
|
|
|
|
regulation of transporter activity
|
GO:0032409 |
82 |
0.057
|
|
|
|
single organism reproductive process
|
GO:0044702 |
98 |
0.056
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.055
|
|
|
|
regulation of ion transport
|
GO:0043269 |
189 |
0.054
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.054
|
|
|
|
regulation of meiotic cell cycle
|
GO:0051445 |
4 |
0.054
|
|
|
|
positive regulation of immune response
|
GO:0050778 |
159 |
0.054
|
|
|
|
epithelium migration
|
GO:0090132 |
119 |
0.053
|
|
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
324 |
0.050
|
|
|
|
cellular lipid catabolic process
|
GO:0044242 |
65 |
0.049
|
|
|
|
organic acid catabolic process
|
GO:0016054 |
71 |
0.049
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
124 |
0.049
|
|
|
|
regulation of anion transport
|
GO:0044070 |
25 |
0.049
|
|
|
|
lens development in camera type eye
|
GO:0002088 |
2 |
0.049
|
|
|
|
reproductive process
|
GO:0022414 |
106 |
0.048
|
|
|
|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
156 |
0.048
|
|
|
|
regulation of ion transmembrane transport
|
GO:0034765 |
132 |
0.048
|
|
|
|
cell cell junction organization
|
GO:0045216 |
69 |
0.048
|
|
|
|
negative regulation of neuron apoptotic process
|
GO:0043524 |
23 |
0.048
|
|
|
|
actin filament organization
|
GO:0007015 |
128 |
0.047
|
|
|
|
dna catabolic process
|
GO:0006308 |
49 |
0.047
|
Mouse |
|
|
cellular response to light stimulus
|
GO:0071482 |
34 |
0.047
|
Human |
|
|
axon regeneration
|
GO:0031103 |
1 |
0.047
|
|
|
|
protein import into nucleus
|
GO:0006606 |
104 |
0.047
|
|
|
|
regulation of response to external stimulus
|
GO:0032101 |
222 |
0.047
|
|
|
|
regulation of apoptotic dna fragmentation
|
GO:1902510 |
3 |
0.047
|
Mouse |
|
|
rna processing
|
GO:0006396 |
255 |
0.047
|
|
|
|
positive regulation of response to external stimulus
|
GO:0032103 |
88 |
0.047
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.047
|
|
|
|
regulation of ion transmembrane transporter activity
|
GO:0032412 |
72 |
0.046
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
107 |
0.045
|
|
|
|
mrna metabolic process
|
GO:0016071 |
175 |
0.045
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
193 |
0.045
|
Human Mouse |
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.044
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
108 |
0.044
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.043
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
191 |
0.043
|
|
|
|
locomotory behavior
|
GO:0007626 |
1 |
0.043
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
172 |
0.043
|
|
|
|
positive regulation of protein k63 linked ubiquitination
|
GO:1902523 |
1 |
0.042
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.042
|
Mouse |
|
|
cellular response to hypoxia
|
GO:0071456 |
51 |
0.042
|
|
|
|
syncytium formation by plasma membrane fusion
|
GO:0000768 |
2 |
0.042
|
|
|
|
dephosphorylation
|
GO:0016311 |
209 |
0.042
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
119 |
0.041
|
|
|
|
lipid biosynthetic process
|
GO:0008610 |
177 |
0.041
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.041
|
|
|
|
response to axon injury
|
GO:0048678 |
1 |
0.041
|
|
|
|
membrane organization
|
GO:0061024 |
292 |
0.041
|
|
|
|
regulation of synaptic plasticity
|
GO:0048167 |
3 |
0.041
|
|
|
|
plasma membrane organization
|
GO:0007009 |
115 |
0.041
|
|
|
|
lipid catabolic process
|
GO:0016042 |
84 |
0.040
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
156 |
0.040
|
Rat |
|
|
autophagy
|
GO:0006914 |
88 |
0.039
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
181 |
0.039
|
|
|
|
endomembrane system organization
|
GO:0010256 |
196 |
0.039
|
|
|
|
positive regulation of ion transport
|
GO:0043270 |
87 |
0.039
|
|
|
|
somatic muscle development
|
GO:0007525 |
1 |
0.039
|
|
|
|
regulation of humoral immune response
|
GO:0002920 |
11 |
0.038
|
|
|
|
aging
|
GO:0007568 |
66 |
0.038
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.038
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.037
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
204 |
0.037
|
Rat |
|
|
positive regulation of superoxide anion generation
|
GO:0032930 |
4 |
0.037
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.037
|
Mouse |
|
|
regulation of homeostatic process
|
GO:0032844 |
121 |
0.036
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
3 |
0.036
|
|
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.036
|
|
|
|
hematopoietic progenitor cell differentiation
|
GO:0002244 |
38 |
0.036
|
|
|
|
cell morphogenesis involved in neuron differentiation
|
GO:0048667 |
44 |
0.036
|
|
|
|
protein linear polyubiquitination
|
GO:0097039 |
5 |
0.036
|
|
|
|
cellular response to alcohol
|
GO:0097306 |
29 |
0.035
|
|
|
|
cell adhesion
|
GO:0007155 |
325 |
0.035
|
|
|
|
circulatory system development
|
GO:0072359 |
262 |
0.035
|
Mouse |
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
2 |
0.035
|
|
|
|
protein glycosylation
|
GO:0006486 |
62 |
0.034
|
|
|
|
astrocyte differentiation
|
GO:0048708 |
4 |
0.034
|
|
|
|
regulation of organ morphogenesis
|
GO:2000027 |
24 |
0.034
|
|
|
|
neuromuscular junction development
|
GO:0007528 |
3 |
0.034
|
|
|
|
negative regulation of protein processing
|
GO:0010955 |
142 |
0.034
|
|
|
|
dendrite development
|
GO:0016358 |
24 |
0.034
|
|
|
|
cellular response to nitrogen compound
|
GO:1901699 |
144 |
0.033
|
|
|
|
positive regulation of protein modification by small protein conjugation or removal
|
GO:1903322 |
61 |
0.033
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
26 |
0.033
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.033
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
177 |
0.032
|
|
|
|
cofactor metabolic process
|
GO:0051186 |
87 |
0.032
|
|
|
|
positive regulation of peptidyl serine phosphorylation
|
GO:0033138 |
42 |
0.032
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
113 |
0.032
|
|
|
|
positive regulation of dna metabolic process
|
GO:0051054 |
73 |
0.032
|
|
|
|
cellular response to peptide
|
GO:1901653 |
59 |
0.032
|
|
|
|
regulation of cell development
|
GO:0060284 |
161 |
0.032
|
|
|
|
carbohydrate biosynthetic process
|
GO:0016051 |
42 |
0.032
|
|
|
|
ceramide metabolic process
|
GO:0006672 |
25 |
0.032
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.031
|
|
|
|
regulation of endothelial cell proliferation
|
GO:0001936 |
56 |
0.031
|
|
|
|
membrane lipid metabolic process
|
GO:0006643 |
53 |
0.031
|
|
|
|
regulation of glial cell proliferation
|
GO:0060251 |
4 |
0.031
|
|
|
|
response to ionizing radiation
|
GO:0010212 |
65 |
0.031
|
Rat |
|
|
t cell apoptotic process
|
GO:0070231 |
12 |
0.031
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
303 |
0.031
|
|
|
|
response to nutrient levels
|
GO:0031667 |
81 |
0.031
|
|
|
|
hindlimb morphogenesis
|
GO:0035137 |
2 |
0.030
|
|
|
|
cochlea development
|
GO:0090102 |
1 |
0.030
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.030
|
Mouse |
|
|
regulation of mononuclear cell proliferation
|
GO:0032944 |
65 |
0.030
|
Mouse |
|
|
positive regulation of epithelial cell proliferation
|
GO:0050679 |
65 |
0.029
|
|
|
|
positive regulation of transporter activity
|
GO:0032411 |
32 |
0.029
|
|
|
|
response to alcohol
|
GO:0097305 |
64 |
0.029
|
Rat |
|
|
forebrain neuron differentiation
|
GO:0021879 |
3 |
0.029
|
|
|
|
positive regulation of cellular component movement
|
GO:0051272 |
181 |
0.029
|
|
|
|
ribonucleoprotein complex assembly
|
GO:0022618 |
78 |
0.029
|
|
|
|
actin filament based process
|
GO:0030029 |
224 |
0.029
|
|
|
|
monocarboxylic acid metabolic process
|
GO:0032787 |
185 |
0.028
|
|
|
|
oogenesis
|
GO:0048477 |
2 |
0.028
|
|
|
|
epithelial cell differentiation
|
GO:0030855 |
141 |
0.028
|
Human Mouse |
|
|
tissue migration
|
GO:0090130 |
119 |
0.028
|
|
|
|
growth
|
GO:0040007 |
202 |
0.028
|
|
|
|
carbohydrate transport
|
GO:0008643 |
37 |
0.027
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.027
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
136 |
0.027
|
|
|
|
macromolecule glycosylation
|
GO:0043413 |
63 |
0.027
|
|
|
|
prostate gland development
|
GO:0030850 |
3 |
0.027
|
|
|
|
regulation of lipid catabolic process
|
GO:0050994 |
23 |
0.027
|
|
|
|
establishment of protein localization to membrane
|
GO:0090150 |
121 |
0.027
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
162 |
0.026
|
|
|
|
positive regulation of protein k48 linked ubiquitination
|
GO:1902524 |
1 |
0.026
|
|
|
|
regulation of growth
|
GO:0040008 |
165 |
0.026
|
|
|
|
positive regulation of endothelial cell migration
|
GO:0010595 |
39 |
0.026
|
|
|
|
regulation of peptidyl serine phosphorylation
|
GO:0033135 |
50 |
0.026
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
408 |
0.026
|
|
|
|
morphogenesis of an epithelium
|
GO:0002009 |
60 |
0.026
|
|
|
|
mrna processing
|
GO:0006397 |
133 |
0.026
|
|
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
131 |
0.026
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
207 |
0.026
|
|
|
|
single organism membrane organization
|
GO:0044802 |
268 |
0.025
|
|
|
|
male gamete generation
|
GO:0048232 |
22 |
0.025
|
|
|
|
spermatid differentiation
|
GO:0048515 |
4 |
0.025
|
|
|
|
regulation of vasculature development
|
GO:1901342 |
97 |
0.025
|
|
|
|
negative regulation of myotube differentiation
|
GO:0010832 |
4 |
0.025
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.025
|
|
|
|
regulation of reactive oxygen species biosynthetic process
|
GO:1903426 |
3 |
0.025
|
|
|
|
monocarboxylic acid catabolic process
|
GO:0072329 |
37 |
0.025
|
|
|
|
jak stat cascade
|
GO:0007259 |
46 |
0.025
|
|
|
|
regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903050 |
91 |
0.025
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.024
|
|
|
|
regulation of thyroid hormone generation
|
GO:2000609 |
2 |
0.024
|
|
|
|
cell substrate adhesion
|
GO:0031589 |
132 |
0.024
|
|
|
|
peptidyl threonine modification
|
GO:0018210 |
45 |
0.024
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.024
|
|
|
|
regulation of cell morphogenesis
|
GO:0022604 |
153 |
0.024
|
|
