|
|
neutral lipid catabolic process
|
GO:0046461 |
12 |
1.000
|
|
|
|
positive regulation of meiotic cell cycle
|
GO:0051446 |
2 |
0.999
|
Worm |
|
|
g2 m transition of mitotic cell cycle
|
GO:0000086 |
41 |
0.997
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.995
|
Fly |
|
|
cell cycle g2 m phase transition
|
GO:0044839 |
43 |
0.992
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.989
|
|
|
|
regulation of cell cycle arrest
|
GO:0071156 |
36 |
0.989
|
|
|
|
regulation of mitosis
|
GO:0007088 |
63 |
0.985
|
Worm Fly |
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.984
|
|
|
|
regulation of triglyceride metabolic process
|
GO:0090207 |
11 |
0.982
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.973
|
Mouse Worm Fly |
|
|
dna dependent dna replication
|
GO:0006261 |
44 |
0.965
|
Mouse |
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.963
|
Mouse Worm Fly |
|
|
dna replication initiation
|
GO:0006270 |
6 |
0.953
|
Mouse |
|
|
mitotic cell cycle phase transition
|
GO:0044772 |
162 |
0.950
|
Worm Fly |
|
|
phosphorylation of rna polymerase ii c terminal domain
|
GO:0070816 |
3 |
0.928
|
|
|
|
dna replication
|
GO:0006260 |
116 |
0.920
|
Mouse Worm Fly |
|
|
glycerolipid catabolic process
|
GO:0046503 |
18 |
0.919
|
|
|
|
regulation of dna replication
|
GO:0006275 |
68 |
0.918
|
Fly |
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.912
|
|
|
|
cell cycle g1 s phase transition
|
GO:0044843 |
80 |
0.907
|
Worm Fly |
|
|
positive regulation of cardiac muscle cell proliferation
|
GO:0060045 |
2 |
0.902
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.893
|
Worm Fly |
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.888
|
|
|
|
epithelial cell differentiation
|
GO:0030855 |
141 |
0.879
|
Fly |
|
|
positive regulation of dna metabolic process
|
GO:0051054 |
73 |
0.875
|
|
|
|
response to camp
|
GO:0051591 |
25 |
0.870
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.865
|
Fly |
|
|
regulation of ubiquitin protein transferase activity
|
GO:0051438 |
28 |
0.849
|
Fly |
|
|
oocyte maturation
|
GO:0001556 |
1 |
0.838
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.833
|
Worm |
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.832
|
|
|
|
double strand break repair
|
GO:0006302 |
101 |
0.832
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.822
|
Fly |
|
|
positive regulation of mitotic cell cycle
|
GO:0045931 |
60 |
0.819
|
Fly |
|
|
positive regulation of fibroblast proliferation
|
GO:0048146 |
21 |
0.815
|
|
|
|
triglyceride catabolic process
|
GO:0019433 |
10 |
0.813
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.810
|
|
|
|
response to organophosphorus
|
GO:0046683 |
41 |
0.806
|
|
|
|
positive regulation of mitotic cell cycle phase transition
|
GO:1901992 |
19 |
0.798
|
Fly |
|
|
dna repair
|
GO:0006281 |
198 |
0.797
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.791
|
|
|
|
negative regulation of transcription from rna polymerase ii promoter
|
GO:0000122 |
281 |
0.785
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.784
|
Mouse Worm Fly |
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.779
|
|
|
|
acylglycerol metabolic process
|
GO:0006639 |
27 |
0.776
|
|
|
|
neuron fate commitment
|
GO:0048663 |
2 |
0.771
|
Fly |
|
|
negative regulation of mitotic cell cycle
|
GO:0045930 |
102 |
0.747
|
Worm Fly |
|
|
negative regulation of cell cycle
|
GO:0045786 |
193 |
0.746
|
Worm Fly |
|
|
gland development
|
GO:0048732 |
48 |
0.728
|
Rat |
|
|
response to radiation
|
GO:0009314 |
151 |
0.713
|
|
|
|
glomerular epithelial cell development
|
GO:0072310 |
3 |
0.711
|
|
|
|
regulation of dna metabolic process
|
GO:0051052 |
153 |
0.704
|
Fly |
|
|
positive regulation of triglyceride metabolic process
|
GO:0090208 |
9 |
0.679
|
|
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
41 |
0.667
|
|
|
|
regulation of cyclin dependent protein serine threonine kinase activity
|
GO:0000079 |
36 |
0.663
|
|
|
|
regeneration
|
GO:0031099 |
4 |
0.660
|
Rat |
|
|
cell cycle arrest
|
GO:0007050 |
71 |
0.658
|
Worm |
|
|
mapk cascade
|
GO:0000165 |
288 |
0.651
|
|
|
|
regulation of triglyceride catabolic process
|
GO:0010896 |
6 |
0.642
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.640
|
Rat Fly |
|
|
positive regulation of cell cycle
|
GO:0045787 |
140 |
0.628
|
Worm Fly |
|
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.623
|
|
|
|
cell cycle phase transition
|
GO:0044770 |
173 |
0.621
|
Worm Fly |
|
|
neuroblast division
|
GO:0055057 |
1 |
0.618
|
|
|
|
neutral lipid metabolic process
|
GO:0006638 |
27 |
0.610
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.606
|
Worm Fly |
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.600
|
Fly |
|
|
urogenital system development
|
GO:0001655 |
65 |
0.596
|
|
|
|
regulation of double strand break repair
|
GO:2000779 |
22 |
0.596
|
|
|
|
negative regulation of cell cycle process
|
GO:0010948 |
121 |
0.584
|
Fly |
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.579
|
Rat |
|
|
positive regulation of response to dna damage stimulus
|
GO:2001022 |
43 |
0.579
|
|
|
|
mitotic cell cycle checkpoint
|
GO:0007093 |
68 |
0.567
|
|
|
|
triglyceride metabolic process
|
GO:0006641 |
23 |
0.559
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.553
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.552
|
Mouse Worm Fly |
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
75 |
0.551
|
|
|
|
cellular response to iron ion
|
GO:0071281 |
1 |
0.549
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
162 |
0.549
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.546
|
|
|
|
cardiovascular system development
|
GO:0072358 |
262 |
0.532
|
|
|
|
regulation of transcription involved in g1 s transition of mitotic cell cycle
|
GO:0000083 |
8 |
0.530
|
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.520
|
Rat |
|
|
kidney morphogenesis
|
GO:0060993 |
19 |
0.506
|
|
|
|
regulation of stress activated protein kinase signaling cascade
|
GO:0070302 |
85 |
0.500
|
|
|
|
regulation of cardiac muscle cell proliferation
|
GO:0060043 |
4 |
0.490
|
|
|
|
positive regulation of cell cycle process
|
GO:0090068 |
106 |
0.488
|
Fly |
|
|
mesonephric epithelium development
|
GO:0072163 |
14 |
0.485
|
|
|
|
lung epithelium development
|
GO:0060428 |
7 |
0.481
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
244 |
0.477
|
Fly |
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.468
|
|
|
|
tube development
|
GO:0035295 |
125 |
0.467
|
|
|
|
epithelial cell development
|
GO:0002064 |
34 |
0.457
|
Fly |
|
|
regulation of meiotic cell cycle
|
GO:0051445 |
4 |
0.453
|
Worm |
|
|
positive regulation of heart growth
|
GO:0060421 |
2 |
0.448
|
|
|
|
chromosome segregation
|
GO:0007059 |
114 |
0.445
|
Fly |
|
|
protein modification by small protein conjugation
|
GO:0032446 |
342 |
0.436
|
Fly |
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.433
|
Fly |
|
|
asymmetric stem cell division
|
GO:0098722 |
1 |
0.427
|
|
|
|
positive regulation of dna repair
|
GO:0045739 |
25 |
0.426
|
|
|
|
regulation of cell cycle phase transition
|
GO:1901987 |
126 |
0.423
|
Fly |
|
|
acylglycerol catabolic process
|
GO:0046464 |
12 |
0.421
|
|
|
|
lung epithelial cell differentiation
|
GO:0060487 |
1 |
0.420
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
155 |
0.416
|
|
|
|
cell cycle checkpoint
|
GO:0000075 |
117 |
0.416
|
|
|
|
negative regulation of ubiquitin protein ligase activity involved in mitotic cell cycle
|
GO:0051436 |
4 |
0.404
|
Fly |
|
|
negative regulation of mitotic cell cycle phase transition
|
GO:1901991 |
85 |
0.402
|
Fly |
|
|
cellular response to abiotic stimulus
|
GO:0071214 |
117 |
0.401
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.400
|
Worm Fly |
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
84 |
0.394
|
|
|
|
peptidyl tyrosine dephosphorylation
|
GO:0035335 |
36 |
0.387
|
|
|
|
dna damage response signal transduction by p53 class mediator resulting in transcription of p21 class mediator
|
GO:0006978 |
11 |
0.387
|
|
|
|
dna conformation change
|
GO:0071103 |
113 |
0.380
|
|
|
|
response to light stimulus
|
GO:0009416 |
87 |
0.369
|
|
|
|
kidney epithelium development
|
GO:0072073 |
25 |
0.369
|
|
|
|
cytokinesis
|
GO:0000910 |
96 |
0.367
|
|
|
|
regulation of cell diameter
|
GO:0060305 |
1 |
0.367
|
|
|
|
metanephros development
|
GO:0001656 |
16 |
0.361
|
|
|
|
cell cycle dna replication
|
GO:0044786 |
11 |
0.361
|
Worm |
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.359
|
|
|
|
cellular response to uv
|
GO:0034644 |
32 |
0.357
|
|
|
|
dna damage response signal transduction resulting in transcription
|
GO:0042772 |
12 |
0.355
|
|
|
|
regulation of mitotic sister chromatid separation
|
GO:0010965 |
27 |
0.355
|
Fly |
|
|
dna damage response signal transduction by p53 class mediator
|
GO:0030330 |
44 |
0.354
|
|
|
|
negative regulation of chromosome organization
|
GO:2001251 |
48 |
0.345
|
Fly |
|
|
signal transduction in response to dna damage
|
GO:0042770 |
57 |
0.342
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.341
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
113 |
0.339
|
|
|
|
autophagic cell death
|
GO:0048102 |
3 |
0.337
|
|
|
|
somatic stem cell division
|
GO:0048103 |
1 |
0.332
|
|
|
|
regulation of response to dna damage stimulus
|
GO:2001020 |
94 |
0.330
|
|
|
|
liver development
|
GO:0001889 |
9 |
0.327
|
Rat |
|
|
regulation of proteasomal protein catabolic process
|
GO:0061136 |
87 |
0.322
|
Fly |
|
|
g1 s transition of mitotic cell cycle
|
GO:0000082 |
78 |
0.322
|
Worm Fly |
|
|
meiosis i
|
GO:0007127 |
4 |
0.315
|
|
|
|
vasculogenesis
|
GO:0001570 |
8 |
0.313
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.311
|
|
|
|
circulatory system development
|
GO:0072359 |
262 |
0.310
|
|
|
|
neuronal stem cell division
|
GO:0036445 |
1 |
0.310
|
|
|
|
negative regulation of mapk cascade
|
GO:0043409 |
56 |
0.306
|
|
|
|
lung cell differentiation
|
GO:0060479 |
1 |
0.291
|
|
|
|
dna packaging
|
GO:0006323 |
77 |
0.291
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.289
|
|
|
|
ureteric bud development
|
GO:0001657 |
13 |
0.284
|
|
|
|
asymmetric neuroblast division
|
GO:0055059 |
1 |
0.283
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.277
|
Worm Fly |
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.270
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.266
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.263
|
|
|
|
metal ion transport
|
GO:0030001 |
272 |
0.248
|
|
|
|
negative regulation of stress activated protein kinase signaling cascade
|
GO:0070303 |
19 |
0.244
|
|
|
|
regulation of lipid catabolic process
|
GO:0050994 |
23 |
0.242
|
|
|
|
vasculature development
|
GO:0001944 |
181 |
0.241
|
|
|
|
glomerulus development
|
GO:0032835 |
15 |
0.241
|
|
|
|
oocyte differentiation
|
GO:0009994 |
2 |
0.239
|
|
|
|
positive regulation of dna replication
|
GO:0045740 |
35 |
0.237
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.235
|
Worm Fly |
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.233
|
|
|
|
lipid metabolic process
|
GO:0006629 |
381 |
0.233
|
|
|
|
glomerular epithelium development
|
GO:0072010 |
7 |
0.232
|
|
|
|
regulation of fibroblast proliferation
|
GO:0048145 |
32 |
0.232
|
|
|
|
regulation of metaphase anaphase transition of cell cycle
|
GO:1902099 |
26 |
0.231
|
Fly |
|
|
kidney development
|
GO:0001822 |
53 |
0.231
|
|
|
|
lipid biosynthetic process
|
GO:0008610 |
177 |
0.226
|
|
|
|
stress activated mapk cascade
|
GO:0051403 |
93 |
0.226
|
|
|
|
positive regulation of cell cycle g2 m phase transition
|
GO:1902751 |
8 |
0.222
|
|
|
|
neurogenesis
|
GO:0022008 |
169 |
0.220
|
Fly |
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
94 |
0.219
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.213
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.211
|
|
|
|
metaphase anaphase transition of cell cycle
|
GO:0044784 |
21 |
0.211
|
Fly |
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.210
|
Fly |
|
|
regulation of epithelial cell differentiation
|
GO:0030856 |
24 |
0.209
|
|
|
|
negative regulation of cell differentiation
|
GO:0045596 |
171 |
0.208
|
Fly |
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.206
|
|
|
|
oocyte development
|
GO:0048599 |
1 |
0.204
|
|
|
|
chemical homeostasis
|
GO:0048878 |
306 |
0.203
|
|
|
|
cell differentiation involved in kidney development
|
GO:0061005 |
9 |
0.194
|
|
|
|
exit from mitosis
|
GO:0010458 |
10 |
0.193
|
Fly |
|
|
negative regulation of protein dephosphorylation
|
GO:0035308 |
3 |
0.192
|
|
|
|
negative regulation of transcription involved in g1 s transition of mitotic cell cycle
|
GO:0071930 |
2 |
0.192
|
|
|
|
covalent chromatin modification
|
GO:0016569 |
254 |
0.191
|
|
|
|
cell adhesion
|
GO:0007155 |
325 |
0.191
|
Fly |
|
|
protein dephosphorylation
|
GO:0006470 |
81 |
0.190
|
|
|
|
glomerular parietal epithelial cell differentiation
|
GO:0072139 |
3 |
0.186
|
|
|
|
tube morphogenesis
|
GO:0035239 |
95 |
0.185
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
128 |
0.184
|
|
|
|
response to uv
|
GO:0009411 |
73 |
0.182
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.182
|
|
|
|
cell fate determination
|
GO:0001709 |
3 |
0.182
|
Fly |
|
|
regulation of dna repair
|
GO:0006282 |
47 |
0.180
|
|
|
|
triglyceride biosynthetic process
|
GO:0019432 |
10 |
0.178
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.177
|
|
|
|
ion homeostasis
|
GO:0050801 |
230 |
0.175
|
|
|
|
negative regulation of dna metabolic process
|
GO:0051053 |
57 |
0.174
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.173
|
|
|
|
regulation of protein ubiquitination
|
GO:0031396 |
95 |
0.171
|
Fly |
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.171
|
|
|
|
mitotic nuclear division
|
GO:0007067 |
119 |
0.170
|
Worm Fly |
|
|
response to metal ion
|
GO:0010038 |
84 |
0.167
|
|
|
|
neuroblast proliferation
|
GO:0007405 |
4 |
0.167
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
303 |
0.166
|
|
|
|
regulation of cardiac muscle tissue growth
|
GO:0055021 |
4 |
0.165
|
|
|
|
mesonephric tubule development
|
GO:0072164 |
14 |
0.164
|
|
|
|
acylglycerol biosynthetic process
|
GO:0046463 |
11 |
0.161
|
|
|
|
chromatin organization
|
GO:0006325 |
351 |
0.161
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
119 |
0.159
|
|
|
|
protein ubiquitination
|
GO:0016567 |
314 |
0.158
|
Fly |
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.157
|
|
|
|
sister chromatid cohesion
|
GO:0007062 |
24 |
0.155
|
|
|
|
dna integrity checkpoint
|
GO:0031570 |
71 |
0.155
|
|
|
|
regulation of sister chromatid cohesion
|
GO:0007063 |
9 |
0.154
|
|
|
|
jak stat cascade
|
GO:0007259 |
46 |
0.154
|
Fly |
|
|
peripheral nervous system development
|
GO:0007422 |
2 |
0.154
|
Fly |
|
|
meiotic cell cycle
|
GO:0051321 |
13 |
0.154
|
Worm |
|
|
positive regulation of proteolysis
|
GO:0045862 |
142 |
0.150
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
261 |
0.148
|
Fly |
|
|
developmental programmed cell death
|
GO:0010623 |
3 |
0.148
|
|
|
|
negative regulation of g1 s transition of mitotic cell cycle
|
GO:2000134 |
29 |
0.148
|
|
|
|
maintenance of location
|
GO:0051235 |
112 |
0.145
|
|
|
|
organ morphogenesis
|
GO:0009887 |
147 |
0.145
|
Fly |
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.145
|
Fly |
|
|
nephron epithelium development
|
GO:0072009 |
23 |
0.144
|
|
|
|
dna damage checkpoint
|
GO:0000077 |
68 |
0.144
|
|
|
|
blood vessel development
|
GO:0001568 |
172 |
0.143
|
|
|
|
response to drug
|
GO:0042493 |
81 |
0.142
|
Rat |
|
|
positive regulation of g2 m transition of mitotic cell cycle
|
GO:0010971 |
8 |
0.141
|
|
|
|
mitotic g1 dna damage checkpoint
|
GO:0031571 |
17 |
0.139
|
|
|
|
somatic stem cell maintenance
|
GO:0035019 |
4 |
0.138
|
Fly |
|
|
positive regulation of cyclin dependent protein serine threonine kinase activity
|
GO:0045737 |
15 |
0.138
|
|
|
|
lipid localization
|
GO:0010876 |
106 |
0.135
|
|
|
|
positive regulation of organ growth
|
GO:0046622 |
2 |
0.134
|
|
|
|
glycerolipid metabolic process
|
GO:0046486 |
107 |
0.133
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.133
|
Fly |
|
|
stem cell division
|
GO:0017145 |
2 |
0.132
|
|
|
|
epithelial cell differentiation involved in kidney development
|
GO:0035850 |
9 |
0.132
|
|
|
|
mitotic dna damage checkpoint
|
GO:0044773 |
28 |
0.132
|
|
|
|
mitotic spindle stabilization
|
GO:0043148 |
2 |
0.132
|
|
|
|
g2 dna damage checkpoint
|
GO:0031572 |
26 |
0.129
|
|
|
|
regulation of g1 s transition of mitotic cell cycle
|
GO:2000045 |
40 |
0.129
|
Fly |
|
|
cardiac muscle cell proliferation
|
GO:0060038 |
6 |
0.126
|
|
|
|
mitotic dna integrity checkpoint
|
GO:0044774 |
30 |
0.126
|
|
|
|
regulation of microtubule polymerization or depolymerization
|
GO:0031110 |
27 |
0.125
|
|
|
|
positive regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043280 |
69 |
0.125
|
|
|
|
regulation of g2 m transition of mitotic cell cycle
|
GO:0010389 |
20 |
0.123
|
|
|
|
response to inorganic substance
|
GO:0010035 |
127 |
0.123
|
|
|
|
dna biosynthetic process
|
GO:0071897 |
40 |
0.123
|
Fly |
|
|
negative regulation of dna replication
|
GO:0008156 |
29 |
0.122
|
|
|
|
ventricular cardiac muscle cell differentiation
|
GO:0055012 |
1 |
0.121
|
|
|
|
positive regulation of cell cycle arrest
|
GO:0071158 |
23 |
0.121
|
|
|
|
response to transition metal nanoparticle
|
GO:1990267 |
29 |
0.119
|
Rat |
|
|
cell type specific apoptotic process
|
GO:0097285 |
125 |
0.118
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
170 |
0.118
|
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
206 |
0.116
|
Fly |
|
|
chromatin modification
|
GO:0016568 |
298 |
0.115
|
|
|
|
negative regulation of stress activated mapk cascade
|
GO:0032873 |
19 |
0.112
|
|
|
|
regulation of chromosome segregation
|
GO:0051983 |
44 |
0.112
|
Fly |
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.110
|
|
|
|
regulation of mitotic cell cycle phase transition
|
GO:1901990 |
118 |
0.108
|
Fly |
|
|
regulation of chromosome organization
|
GO:0033044 |
103 |
0.108
|
Fly |
|
|
response to organic cyclic compound
|
GO:0014070 |
204 |
0.108
|
Rat |
|
|
negative regulation of cell cycle phase transition
|
GO:1901988 |
89 |
0.108
|
Fly |
|
|
endocytosis
|
GO:0006897 |
159 |
0.107
|
|
|
|
negative regulation of organelle organization
|
GO:0010639 |
126 |
0.107
|
Fly |
|
|
regulation of microtubule based process
|
GO:0032886 |
74 |
0.106
|
|
|
|
double strand break repair via homologous recombination
|
GO:0000724 |
50 |
0.106
|
|
|
|
male meiosis
|
GO:0007140 |
1 |
0.103
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
104 |
0.103
|
|
|
|
negative regulation of chromosome segregation
|
GO:0051985 |
18 |
0.102
|
Fly |
|
|
glomerular epithelial cell differentiation
|
GO:0072311 |
5 |
0.101
|
|
|
|
negative regulation of mitotic anaphase promoting complex activity
|
GO:0060564 |
4 |
0.100
|
Fly |
|
|
positive regulation of epithelial cell differentiation
|
GO:0030858 |
14 |
0.098
|
|
|
|
mesonephros development
|
GO:0001823 |
17 |
0.098
|
|
|
|
7 methylguanosine mrna capping
|
GO:0006370 |
7 |
0.097
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.097
|
|
|
|
histone modification
|
GO:0016570 |
251 |
0.097
|
|
|
|
positive regulation of nuclear cell cycle dna replication
|
GO:0010571 |
4 |
0.097
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.095
|
|
|
|
positive regulation of leukocyte activation
|
GO:0002696 |
80 |
0.095
|
|
|
|
regulation of protein modification by small protein conjugation or removal
|
GO:1903320 |
107 |
0.094
|
Fly |
|
|
cellular response to radiation
|
GO:0071478 |
65 |
0.094
|
|
|
|
regulation of spindle organization
|
GO:0090224 |
10 |
0.094
|
|
|
|
negative regulation of meiotic cell cycle
|
GO:0051447 |
2 |
0.094
|
|
|
|
dna catabolic process exonucleolytic
|
GO:0000738 |
17 |
0.093
|
|
|
|
regulation of dna dependent dna replication initiation
|
GO:0030174 |
3 |
0.091
|
|
|
|
dna endoreduplication
|
GO:0042023 |
5 |
0.091
|
Worm |
|
|
nuclear division
|
GO:0000280 |
128 |
0.091
|
Worm Fly |
|
|
mitotic sister chromatid segregation
|
GO:0000070 |
53 |
0.090
|
Fly |
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.090
|
Rat Worm |
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.090
|
|
|
|
protein localization to kinetochore
|
GO:0034501 |
10 |
0.087
|
|
|
|
cellular response to lithium ion
|
GO:0071285 |
2 |
0.087
|
|
|
|
negative regulation of cell size
|
GO:0045792 |
3 |
0.087
|
|
|
|
regulation of nuclear division
|
GO:0051783 |
65 |
0.086
|
Worm Fly |
|
|
negative regulation of epithelial cell proliferation
|
GO:0050680 |
48 |
0.086
|
|
|
|
regulation of small gtpase mediated signal transduction
|
GO:0051056 |
156 |
0.085
|
|
|
|
cellular lipid catabolic process
|
GO:0044242 |
65 |
0.084
|
|
|
|
regulation of cellular protein catabolic process
|
GO:1903362 |
96 |
0.084
|
Fly |
|
|
protein polyubiquitination
|
GO:0000209 |
110 |
0.083
|
|
|
|
positive regulation of peptidyl tyrosine phosphorylation
|
GO:0050731 |
85 |
0.082
|
|
|
|
nephron development
|
GO:0072006 |
30 |
0.081
|
|
|
|
biological adhesion
|
GO:0022610 |
331 |
0.081
|
Fly |
|
|
negative regulation of sister chromatid segregation
|
GO:0033046 |
17 |
0.081
|
Fly |
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.079
|
|
|
|
response to electrical stimulus
|
GO:0051602 |
1 |
0.078
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.078
|
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.076
|
Fly |
|
|
response to hormone
|
GO:0009725 |
175 |
0.075
|
Rat |
|
|
regulation of cell aging
|
GO:0090342 |
18 |
0.075
|
|
|
|
regulation of cell cycle g2 m phase transition
|
GO:1902749 |
22 |
0.074
|
|
|
|
cellular response to hypoxia
|
GO:0071456 |
51 |
0.073
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
189 |
0.072
|
Worm Fly |
|
|
regulation of dna dependent dna replication
|
GO:0090329 |
19 |
0.072
|
|
|
|
positive regulation of epithelial cell proliferation
|
GO:0050679 |
65 |
0.071
|
|
|
|
regulation of double strand break repair via homologous recombination
|
GO:0010569 |
11 |
0.071
|
|
|
|
regulation of body fluid levels
|
GO:0050878 |
99 |
0.071
|
|
|
|
cell fate commitment
|
GO:0045165 |
27 |
0.071
|
Fly |
|
|
cellular response to nitrogen compound
|
GO:1901699 |
144 |
0.071
|
|
|
|
positive regulation of lipid catabolic process
|
GO:0050996 |
13 |
0.071
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.070
|
|
|
|
regulation of myeloid cell differentiation
|
GO:0045637 |
81 |
0.070
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
63 |
0.069
|
|
|
|
hepaticobiliary system development
|
GO:0061008 |
10 |
0.069
|
Rat |
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.068
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
180 |
0.068
|
|
|
|
positive regulation of attachment of spindle microtubules to kinetochore
|
GO:0051987 |
2 |
0.068
|
|
|
|
chromosome condensation
|
GO:0030261 |
15 |
0.067
|
|
|
|
type b pancreatic cell development
|
GO:0003323 |
4 |
0.067
|
|
|
|
positive regulation of proteasomal protein catabolic process
|
GO:1901800 |
35 |
0.066
|
|
|
|
fibroblast proliferation
|
GO:0048144 |
33 |
0.065
|
|
|
|
lipid homeostasis
|
GO:0055088 |
39 |
0.064
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
140 |
0.064
|
|
|
|
dna catabolic process
|
GO:0006308 |
49 |
0.064
|
|
|
|
renal system development
|
GO:0072001 |
63 |
0.063
|
|
|
|
positive regulation of cytoskeleton organization
|
GO:0051495 |
83 |
0.063
|
|
|
|
neutral lipid biosynthetic process
|
GO:0046460 |
11 |
0.063
|
|
|
|
centrosome organization
|
GO:0051297 |
58 |
0.063
|
|
|
|
dna double strand break processing
|
GO:0000729 |
10 |
0.063
|
|
|
|
oogenesis
|
GO:0048477 |
2 |
0.062
|
Fly |
|
|
cell aging
|
GO:0007569 |
52 |
0.062
|
|
|
|
regulation of lipid metabolic process
|
GO:0019216 |
96 |
0.062
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
0.061
|
|
|
|
histone ubiquitination
|
GO:0016574 |
31 |
0.060
|
|
|
|
negative regulation of mitotic metaphase anaphase transition
|
GO:0045841 |
17 |
0.060
|
Fly |
|
|
regulation of exit from mitosis
|
GO:0007096 |
6 |
0.059
|
Fly |
|
|
regulation of cell division
|
GO:0051302 |
116 |
0.059
|
Worm Fly |
|
|
defense response
|
GO:0006952 |
315 |
0.058
|
|
|
|
monovalent inorganic cation transport
|
GO:0015672 |
128 |
0.058
|
|
|
|
response to purine containing compound
|
GO:0014074 |
40 |
0.057
|
Rat |
|
|
cell division
|
GO:0051301 |
168 |
0.056
|
Worm Fly |
|
|
nucleic acid phosphodiester bond hydrolysis
|
GO:0090305 |
102 |
0.056
|
|
|
|
signal transduction by p53 class mediator
|
GO:0072331 |
72 |
0.056
|
|
|
|
organelle assembly
|
GO:0070925 |
176 |
0.056
|
|
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
212 |
0.055
|
Fly |
|
|
response to axon injury
|
GO:0048678 |
1 |
0.055
|
|
|
|
receptor mediated endocytosis
|
GO:0006898 |
84 |
0.055
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.055
|
|
|
|
centrosome duplication
|
GO:0051298 |
28 |
0.053
|
|
|
|
cellular response to fatty acid
|
GO:0071398 |
8 |
0.053
|
|
|
|
cellular response to peptide
|
GO:1901653 |
59 |
0.053
|
|
|
|
cation transport
|
GO:0006812 |
331 |
0.052
|
|
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043281 |
116 |
0.052
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
181 |
0.052
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
170 |
0.052
|
|
|
|
negative regulation of microtubule polymerization or depolymerization
|
GO:0031111 |
17 |
0.051
|
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
127 |
0.050
|
|
|
|
developmental process involved in reproduction
|
GO:0003006 |
66 |
0.050
|
Rat Worm Fly |
|
|
positive regulation of cell cycle phase transition
|
GO:1901989 |
22 |
0.049
|
Fly |
|
|
modification dependent protein catabolic process
|
GO:0019941 |
209 |
0.048
|
Fly |
|
|
cellular response to lipid
|
GO:0071396 |
127 |
0.048
|
|
|
|
immune response
|
GO:0006955 |
307 |
0.048
|
|
|
|
positive regulation of cellular protein catabolic process
|
GO:1903364 |
37 |
0.047
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.046
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.046
|
|
|
|
regulation of cellular component size
|
GO:0032535 |
82 |
0.046
|
|
|
|
positive regulation of muscle organ development
|
GO:0048636 |
7 |
0.046
|
|
|
|
generation of neurons
|
GO:0048699 |
152 |
0.045
|
Fly |
|
|
positive regulation of chromosome organization
|
GO:2001252 |
41 |
0.045
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
408 |
0.044
|
|
|
|
negative regulation of cellular component movement
|
GO:0051271 |
106 |
0.044
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
180 |
0.044
|
|
|
|
glycerolipid biosynthetic process
|
GO:0045017 |
51 |
0.044
|
|
|
|
neuron apoptotic process
|
GO:0051402 |
39 |
0.044
|
|
|
|
metanephros morphogenesis
|
GO:0003338 |
9 |
0.043
|
|
|
|
intrinsic apoptotic signaling pathway in response to oxidative stress
|
GO:0008631 |
21 |
0.043
|
|
|
|
golgi organization
|
GO:0007030 |
38 |
0.043
|
|
|
|
respiratory system development
|
GO:0060541 |
22 |
0.043
|
|
|
|
negative regulation of cellular catabolic process
|
GO:0031330 |
83 |
0.043
|
Fly |
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
61 |
0.043
|
|
|
|
regulation of triglyceride biosynthetic process
|
GO:0010866 |
5 |
0.043
|
|
|
|
negative regulation of proteasomal protein catabolic process
|
GO:1901799 |
32 |
0.043
|
Fly |
|
|
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic process
|
GO:0031145 |
25 |
0.042
|
Fly |
|
|
response to fatty acid
|
GO:0070542 |
13 |
0.042
|
|
|
|
secretion
|
GO:0046903 |
254 |
0.041
|
|
|
|
metaphase anaphase transition of mitotic cell cycle
|
GO:0007091 |
21 |
0.041
|
Fly |
|
|
dephosphorylation
|
GO:0016311 |
209 |
0.041
|
|
|
|
er nucleus signaling pathway
|
GO:0006984 |
23 |
0.040
|
|
|
|
cardiocyte differentiation
|
GO:0035051 |
23 |
0.040
|
|
|
|
intrinsic apoptotic signaling pathway in response to dna damage
|
GO:0008630 |
50 |
0.040
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.040
|
|
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.039
|
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
176 |
0.039
|
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
155 |
0.038
|
Fly |
|
|
immune effector process
|
GO:0002252 |
159 |
0.038
|
|
|
|
peptidyl serine phosphorylation
|
GO:0018105 |
101 |
0.038
|
|
|
|
cellular response to peptide hormone stimulus
|
GO:0071375 |
56 |
0.038
|
|
|
|
response to oxidative stress
|
GO:0006979 |
121 |
0.038
|
|
|
|
regulation of protein import into nucleus translocation
|
GO:0033158 |
10 |
0.038
|
|
|
|
response to lipid
|
GO:0033993 |
206 |
0.038
|
Rat |
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.037
|
|
|
|
positive regulation of immune system process
|
GO:0002684 |
283 |
0.037
|
|
|
|
positive regulation of immune response
|
GO:0050778 |
159 |
0.037
|
|
|
|
enteroendocrine cell differentiation
|
GO:0035883 |
6 |
0.037
|
|
|
|
positive regulation of chromosome segregation
|
GO:0051984 |
9 |
0.037
|
|
|
|
organophosphate biosynthetic process
|
GO:0090407 |
163 |
0.037
|
|
|
|
single organism carbohydrate metabolic process
|
GO:0044723 |
193 |
0.036
|
|
|
|
protein maturation
|
GO:0051604 |
233 |
0.036
|
Fly |
|
|
tissue regeneration
|
GO:0042246 |
3 |
0.036
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
398 |
0.036
|
|
|
|
humoral immune response
|
GO:0006959 |
49 |
0.036
|
|
|
|
cellular response to decreased oxygen levels
|
GO:0036294 |
51 |
0.036
|
|
|
|
meiotic nuclear division
|
GO:0007126 |
10 |
0.036
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.036
|
Fly |
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
99 |
0.035
|
|
|
|
protein processing
|
GO:0016485 |
226 |
0.035
|
Fly |
|
|
response to alcohol
|
GO:0097305 |
64 |
0.035
|
Rat |
|
|
positive regulation of reactive oxygen species metabolic process
|
GO:2000379 |
24 |
0.035
|
|
|
|
fatty acid homeostasis
|
GO:0055089 |
3 |
0.034
|
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.034
|
Fly |
|
|
centriole replication
|
GO:0007099 |
13 |
0.034
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.034
|
Fly |
|
|
ion transmembrane transport
|
GO:0034220 |
338 |
0.034
|
|
|
|
cellular response to toxic substance
|
GO:0097237 |
4 |
0.034
|
|
|
|
response to external biotic stimulus
|
GO:0043207 |
261 |
0.034
|
|
|
|
peptidyl threonine phosphorylation
|
GO:0018107 |
41 |
0.034
|
|
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.033
|
|
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
127 |
0.033
|
|
|
|
cellular response to metal ion
|
GO:0071248 |
43 |
0.033
|
|
|
|
response to magnesium ion
|
GO:0032026 |
3 |
0.033
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.033
|
|
|
|
regulation of protein dephosphorylation
|
GO:0035304 |
18 |
0.033
|
|
|
|
recombinational repair
|
GO:0000725 |
50 |
0.033
|
|
|
|
metaphase plate congression
|
GO:0051310 |
18 |
0.033
|
|
|
|
mitotic cell cycle arrest
|
GO:0071850 |
4 |
0.033
|
Worm |
|
|
reproductive process
|
GO:0022414 |
106 |
0.033
|
Rat Worm Fly |
|
|
digestive tract development
|
GO:0048565 |
75 |
0.032
|
|
|
|
female sex differentiation
|
GO:0046660 |
12 |
0.032
|
Rat |
|
|
regulation of chromatin binding
|
GO:0035561 |
3 |
0.032
|
|
|
|
activation of protein kinase activity
|
GO:0032147 |
90 |
0.032
|
|
|
|
regulation of cell cycle g1 s phase transition
|
GO:1902806 |
42 |
0.032
|
Fly |
|
|
response to ethanol
|
GO:0045471 |
11 |
0.032
|
Rat |
|
|
cofactor metabolic process
|
GO:0051186 |
87 |
0.032
|
|
|
|
neuron death
|
GO:0070997 |
65 |
0.031
|
|
|
|
negative regulation of epithelial cell differentiation
|
GO:0030857 |
6 |
0.031
|
|
|
|
positive regulation of mrna 3 end processing
|
GO:0031442 |
12 |
0.031
|
|
|
|
negative regulation of cell cycle g1 s phase transition
|
GO:1902807 |
29 |
0.031
|
|
|
|
secretion by cell
|
GO:0032940 |
226 |
0.031
|
|
|
|
dna recombination
|
GO:0006310 |
77 |
0.031
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
175 |
0.031
|
|
|
|
cell projection organization
|
GO:0030030 |
252 |
0.031
|
|
|
|
regulation of binding
|
GO:0051098 |
111 |
0.031
|
|
|
|
response to virus
|
GO:0009615 |
126 |
0.031
|
|
|
|
lens development in camera type eye
|
GO:0002088 |
2 |
0.031
|
|
|
|
protein stabilization
|
GO:0050821 |
64 |
0.030
|
|
|
|
ribonucleoside monophosphate metabolic process
|
GO:0009161 |
187 |
0.030
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.030
|
|
|
|
zymogen activation
|
GO:0031638 |
70 |
0.029
|
|
|
|
histone phosphorylation
|
GO:0016572 |
16 |
0.029
|
|
|
|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
156 |
0.029
|
Fly |
|
|
epithelium development
|
GO:0060429 |
227 |
0.029
|
Fly |
|
|
regulation of angiogenesis
|
GO:0045765 |
92 |
0.028
|
|
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.028
|
|
|
|
histone serine phosphorylation
|
GO:0035404 |
4 |
0.028
|
|
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
70 |
0.028
|
|
|
|
cardiac muscle tissue development
|
GO:0048738 |
39 |
0.028
|
|
|
|
mitotic cytokinesis
|
GO:0000281 |
19 |
0.028
|
|
|
|
cell cell signaling
|
GO:0007267 |
155 |
0.028
|
|
|
|
regulation of striated muscle tissue development
|
GO:0016202 |
26 |
0.027
|
|
|
|
response to wounding
|
GO:0009611 |
168 |
0.027
|
|
|
|
response to ionizing radiation
|
GO:0010212 |
65 |
0.027
|
|
|
|
protein autoubiquitination
|
GO:0051865 |
37 |
0.027
|
|
|
|
embryo development
|
GO:0009790 |
123 |
0.027
|
Worm |
