IMP

Process View

Homo sapiens

25 genes annotated in human

Multi-species View

positive regulation of dna repair

GO:0045739

Any process that activates or increases the frequency, rate or extent of DNA repair.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "positive regulation of dna repair"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "positive regulation of dna repair" (in gray)

Name	Description	Probability	Func Analog Organism
FGFR2	fibroblast growth factor receptor 2	0.997
FAM175A	family with sequence similarity 175, member A	0.979
BRCC3	BRCA1/BRCA2-containing complex, subunit 3	0.951
BRE	brain and reproductive organ-expressed (TNFRSF1A modulator)	0.888
ERBB2	v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)	0.695	Human
EGFR	epidermal growth factor receptor	0.593
ERBB3	v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)	0.560	Human
UIMC1	ubiquitin interaction motif containing 1	0.533
FGF1	fibroblast growth factor 1 (acidic)	0.443	Human
NOXA1	NADPH oxidase activator 1	0.442
CCNE1	cyclin E1	0.426
MDC1	mediator of DNA-damage checkpoint 1	0.387
BABAM1	BRISC and BRCA1 A complex member 1	0.373
ARNTL	aryl hydrocarbon receptor nuclear translocator-like	0.362
UBE2N	ubiquitin-conjugating enzyme E2N (UBC13 homolog, yeast)	0.341
DDIT3	DNA-damage-inducible transcript 3	0.332
H2AFX	H2A histone family, member X	0.252
TP53BP1	tumor protein p53 binding protein 1	0.240
PARD6A	par-6 partitioning defective 6 homolog alpha (C. elegans)	0.201
FGFR1	fibroblast growth factor receptor 1	0.181
FAM175B	family with sequence similarity 175, member B	0.161	Human
ERCC6	excision repair cross-complementing rodent repair deficiency, complementation group 6	0.149
PIK3R2	phosphoinositide-3-kinase, regulatory subunit 2 (beta)	0.147
LRP1	low density lipoprotein receptor-related protein 1	0.144
ANKS1B	ankyrin repeat and sterile alpha motif domain containing 1B	0.137
FGF10	fibroblast growth factor 10	0.122
CDK2	cyclin-dependent kinase 2	0.112
UHRF2	ubiquitin-like with PHD and ring finger domains 2	0.092
ZNRF1	zinc and ring finger 1	0.083
GTF2H2	general transcription factor IIH, polypeptide 2, 44kDa	0.078
CBL	Cas-Br-M (murine) ecotropic retroviral transforming sequence	0.075
CDCP1	CUB domain containing protein 1	0.072
PRKCZ	protein kinase C, zeta	0.071	Human
CREBBP	CREB binding protein	0.071
RNF11	ring finger protein 11	0.068
FGF7	fibroblast growth factor 7	0.063	Human
PPP1CA	protein phosphatase 1, catalytic subunit, alpha isozyme	0.058
ATF4	activating transcription factor 4 (tax-responsive enhancer element B67)	0.055
RELA	v-rel reticuloendotheliosis viral oncogene homolog A (avian)	0.055
SUPT16H	suppressor of Ty 16 homolog (S. cerevisiae)	0.053
PARD3	par-3 partitioning defective 3 homolog (C. elegans)	0.052
PARD6B	par-6 partitioning defective 6 homolog beta (C. elegans)	0.048
SKIL	SKI-like oncogene	0.045
SHC1	SHC (Src homology 2 domain containing) transforming protein 1	0.044
MAGEA2	melanoma antigen family A, 2	0.044
HDAC3	histone deacetylase 3	0.042
PARD6G	par-6 partitioning defective 6 homolog gamma (C. elegans)	0.039
DCTN1	dynactin 1	0.038
UBE2V1	ubiquitin-conjugating enzyme E2 variant 1	0.038
RNF8	ring finger protein 8	0.034
APP	amyloid beta (A4) precursor protein	0.032
DLG4	discs, large homolog 4 (Drosophila)	0.031
AKT1	v-akt murine thymoma viral oncogene homolog 1	0.030	Human
NBN	nibrin	0.028
IMPDH2	IMP (inosine 5'-monophosphate) dehydrogenase 2	0.028
SYK	spleen tyrosine kinase	0.028
CARD11	caspase recruitment domain family, member 11	0.028
CHEK2	CHK2 checkpoint homolog (S. pombe)	0.028
GRIN2C	glutamate receptor, ionotropic, N-methyl D-aspartate 2C	0.027
ZNF71	zinc finger protein 71	0.027
COPS2	COP9 constitutive photomorphogenic homolog subunit 2 (Arabidopsis)	0.027
CEBPB	CCAAT/enhancer binding protein (C/EBP), beta	0.027
CCDC115	coiled-coil domain containing 115	0.026
PPP5C	protein phosphatase 5, catalytic subunit	0.026
TRO	trophinin	0.025
CCL14	chemokine (C-C motif) ligand 14	0.025
TSC22D1	TSC22 domain family, member 1	0.024
BAG3	BCL2-associated athanogene 3	0.023
SH3RF1	SH3 domain containing ring finger 1	0.022
SHMT2	serine hydroxymethyltransferase 2 (mitochondrial)	0.022
SIX1	SIX homeobox 1	0.022
INSR	insulin receptor	0.022
NCF1	neutrophil cytosolic factor 1	0.021
POLD1	polymerase (DNA directed), delta 1, catalytic subunit 125kDa	0.021
DLG2	discs, large homolog 2 (Drosophila)	0.021
PRKCB	protein kinase C, beta	0.021
SMAD3	SMAD family member 3	0.021
PPP1R9B	protein phosphatase 1, regulatory (inhibitor) subunit 9B	0.020
CDC25B	cell division cycle 25 homolog B (S. pombe)	0.019
BARD1	BRCA1 associated RING domain 1	0.019
FGF8	fibroblast growth factor 8 (androgen-induced)	0.018
PLCG1	phospholipase C, gamma 1	0.018
FBXW7	F-box and WD repeat domain containing 7	0.018
BRCA1	breast cancer 1, early onset	0.017
NUDT3	nudix (nucleoside diphosphate linked moiety X)-type motif 3	0.017
CARS	cysteinyl-tRNA synthetase	0.017
PPP2CA	protein phosphatase 2, catalytic subunit, alpha isozyme	0.017
EP300	E1A binding protein p300	0.017
KIAA1712	KIAA1712	0.016
TCP1	t-complex 1	0.016
UBE2D2	ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast)	0.016
HIST2H2AC	histone cluster 2, H2ac	0.015
BRAP	BRCA1 associated protein	0.015
SESN2	sestrin 2	0.014
MPHOSPH6	M-phase phosphoprotein 6	0.014
EIF3D	eukaryotic translation initiation factor 3, subunit D	0.014
SPRR2A	small proline-rich protein 2A	0.014
SNAPC5	small nuclear RNA activating complex, polypeptide 5, 19kDa	0.014
ACACA	acetyl-CoA carboxylase alpha	0.014
MALT1	mucosa associated lymphoid tissue lymphoma translocation gene 1	0.014
ABL2	v-abl Abelson murine leukemia viral oncogene homolog 2	0.014
PAG1	phosphoprotein associated with glycosphingolipid microdomains 1	0.014
TRIM33	tripartite motif containing 33	0.013	Human
DDR2	discoidin domain receptor tyrosine kinase 2	0.013
CSK	c-src tyrosine kinase	0.013
ABL1	c-abl oncogene 1, non-receptor tyrosine kinase	0.013
WRN	Werner syndrome, RecQ helicase-like	0.013
NCOR1	nuclear receptor corepressor 1	0.013
SFN	stratifin	0.013
ZAP70	zeta-chain (TCR) associated protein kinase 70kDa	0.013
CKS2	CDC28 protein kinase regulatory subunit 2	0.013
HNRNPAB	heterogeneous nuclear ribonucleoprotein A/B	0.013
PRKCA	protein kinase C, alpha	0.012
TCF12	transcription factor 12	0.012
RAD50	RAD50 homolog (S. cerevisiae)	0.012
DBP	D site of albumin promoter (albumin D-box) binding protein	0.012
SEC16A	SEC16 homolog A (S. cerevisiae)	0.012
NTRK1	neurotrophic tyrosine kinase, receptor, type 1	0.012
MRPL53	mitochondrial ribosomal protein L53	0.011
PPP4R1	protein phosphatase 4, regulatory subunit 1	0.011
PPP2R1A	protein phosphatase 2, regulatory subunit A, alpha	0.011
USP7	ubiquitin specific peptidase 7 (herpes virus-associated)	0.011
EIF3CL	eukaryotic translation initiation factor 3, subunit C-like	0.011
CDK7	cyclin-dependent kinase 7	0.011
NUMB	numb homolog (Drosophila)	0.011
NMT2	N-myristoyltransferase 2	0.011
PPP2R2D	protein phosphatase 2, regulatory subunit B, delta	0.011
RNF168	ring finger protein 168	0.011
WNT1	wingless-type MMTV integration site family, member 1	0.011
RIN1	Ras and Rab interactor 1	0.010
ASXL1	additional sex combs like 1 (Drosophila)	0.010
PPP6R3	protein phosphatase 6, regulatory subunit 3	0.010
KEAP1	kelch-like ECH-associated protein 1	0.010
GTF2H1	general transcription factor IIH, polypeptide 1, 62kDa	0.010
FGFR3	fibroblast growth factor receptor 3	0.010
TRIM24	tripartite motif containing 24	0.010	Human
POFUT1	protein O-fucosyltransferase 1	0.010
ARNTL2	aryl hydrocarbon receptor nuclear translocator-like 2	0.010