Homo sapiens

58 known processes

CDK1

cyclin-dependent kinase 1

(Aliases: MGC111195,CDC28A,CDC2,P34CDC2,DKFZp686L20222)

CDK1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of cell cycle GO:0051726 393 0.999
oocyte maturation GO:0001556 1 0.997
Worm
neuroblast division GO:0055057 1 0.991
Fly
somatic stem cell division GO:0048103 1 0.966
Fly
mitotic cell cycle process GO:1903047 286 0.961
Mouse Worm Fly
regulation of cell cycle process GO:0010564 266 0.946
Yeast Mouse Worm Fly
cytokinesis GO:0000910 96 0.945
regulation of attachment of spindle microtubules to kinetochore GO:0051988 9 0.941
mitotic nuclear division GO:0007067 119 0.905
Worm
cell cycle g2 m phase transition GO:0044839 43 0.902
Fly
mitotic cytokinesis GO:0000281 19 0.897
cellular response to iron ion GO:0071281 1 0.891
spindle assembly GO:0051225 29 0.888
mitotic cell cycle GO:0000278 326 0.870
Yeast Mouse Rat Worm Fly
microtubule cytoskeleton organization GO:0000226 176 0.869
Yeast
histone serine phosphorylation GO:0035404 4 0.860
positive regulation of cell cycle GO:0045787 140 0.821
Yeast Rat Worm
negative regulation of meiotic cell cycle GO:0051447 2 0.801
Yeast
positive regulation of attachment of spindle microtubules to kinetochore GO:0051987 2 0.788
positive regulation of cell proliferation GO:0008284 301 0.782
Human Rat
histone modification GO:0016570 251 0.752
Human Rat
dephosphorylation GO:0016311 209 0.727
spindle organization GO:0007051 53 0.725
nuclear division GO:0000280 128 0.721
Yeast Worm Fly
negative regulation of cell cycle GO:0045786 193 0.707
Yeast Mouse Fly
negative regulation of phosphorus metabolic process GO:0010563 267 0.699
regulation of mitotic cell cycle GO:0007346 189 0.670
Yeast Mouse Rat Fly
regulation of protein kinase activity GO:0045859 289 0.669
Worm
spindle stabilization GO:0043146 4 0.666
negative regulation of microtubule polymerization or depolymerization GO:0031111 17 0.663
regulation of meiotic cell cycle GO:0051445 4 0.654
Yeast Worm
organelle fission GO:0048285 149 0.651
Yeast Worm Fly
negative regulation of phosphate metabolic process GO:0045936 267 0.640
positive regulation of cell cycle process GO:0090068 106 0.624
Yeast Worm
regulation of microtubule based process GO:0032886 74 0.618
Yeast
positive regulation of protein phosphorylation GO:0001934 313 0.617
Worm
regulation of microtubule cytoskeleton organization GO:0070507 61 0.611
Yeast
stem cell division GO:0017145 2 0.608
Fly
positive regulation of protein kinase activity GO:0045860 190 0.595
Worm
neuronal stem cell division GO:0036445 1 0.594
Fly
post embryonic development GO:0009791 2 0.580
negative regulation of cell cycle process GO:0010948 121 0.577
Yeast Mouse Fly
spindle assembly involved in mitosis GO:0090307 12 0.568
circulatory system development GO:0072359 262 0.565
Rat
regulation of dephosphorylation GO:0035303 96 0.564
negative regulation of cellular component organization GO:0051129 235 0.552
Yeast
spindle midzone assembly GO:0051255 4 0.537
organelle localization GO:0051640 84 0.531
Worm
regulation of spindle organization GO:0090224 10 0.526
positive regulation of mitotic cell cycle GO:0045931 60 0.521
Yeast Rat
chromatin modification GO:0016568 298 0.505
Human Yeast Rat
negative regulation of dephosphorylation GO:0035305 63 0.485
regulation of cell differentiation GO:0045595 393 0.484
positive regulation of organelle organization GO:0010638 195 0.483
Yeast Worm
cell division GO:0051301 168 0.479
Yeast Worm Fly
cytoskeleton dependent cytokinesis GO:0061640 22 0.466
mitotic sister chromatid segregation GO:0000070 53 0.459
modification dependent macromolecule catabolic process GO:0043632 212 0.454
small gtpase mediated signal transduction GO:0007264 78 0.448
Human
positive regulation of cardiac muscle cell proliferation GO:0060045 2 0.444
Rat
cellular macromolecule catabolic process GO:0044265 380 0.441
Yeast
neuroblast proliferation GO:0007405 4 0.433
Fly
cell cycle g1 s phase transition GO:0044843 80 0.418
Fly
g1 s transition of mitotic cell cycle GO:0000082 78 0.415
Fly
covalent chromatin modification GO:0016569 254 0.412
Human Rat
asymmetric stem cell division GO:0098722 1 0.412
Fly
cellular component disassembly GO:0022411 92 0.406
microtubule based process GO:0007017 210 0.404
Yeast
negative regulation of catalytic activity GO:0043086 335 0.392
protein depolymerization GO:0051261 30 0.391
modification dependent protein catabolic process GO:0019941 209 0.387
microtubule organizing center organization GO:0031023 62 0.387
Yeast
positive regulation of developmental process GO:0051094 314 0.380
Rat
positive regulation of cell division GO:0051781 59 0.380
Worm
regulation of mitotic spindle organization GO:0060236 6 0.369
negative regulation of organelle organization GO:0010639 126 0.363
Yeast
chromatin organization GO:0006325 351 0.350
Human Yeast Rat
regulation of cytoskeleton organization GO:0051493 177 0.348
Yeast
regulation of chromosome segregation GO:0051983 44 0.346
Yeast
meiosis i GO:0007127 4 0.345
Yeast
protein localization to kinetochore GO:0034501 10 0.344
protein complex disassembly GO:0043241 52 0.341
cell fate determination GO:0001709 3 0.336
maintenance of location GO:0051235 112 0.334
protein autophosphorylation GO:0046777 123 0.332
negative regulation of protein dephosphorylation GO:0035308 3 0.324
g2 dna damage checkpoint GO:0031572 26 0.323
Mouse Fly
chromosome segregation GO:0007059 114 0.322
Yeast
organelle assembly GO:0070925 176 0.322
protein modification by small protein conjugation GO:0032446 342 0.321
attachment of spindle microtubules to kinetochore GO:0008608 17 0.306
ubiquitin dependent protein catabolic process GO:0006511 206 0.301
tube development GO:0035295 125 0.301
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.297
centrosome organization GO:0051297 58 0.294
nucleoside phosphate catabolic process GO:1901292 412 0.293
regulation of cellular response to stress GO:0080135 244 0.291
Yeast
cell cycle phase transition GO:0044770 173 0.291
Mouse Fly
cell cycle checkpoint GO:0000075 117 0.286
Mouse Fly
purine nucleoside triphosphate catabolic process GO:0009146 392 0.285
regulation of cell cycle phase transition GO:1901987 126 0.281
Mouse Fly
mitotic cell cycle phase transition GO:0044772 162 0.275
Mouse Fly
g2 m transition of mitotic cell cycle GO:0000086 41 0.260
Fly
regeneration GO:0031099 4 0.258
Rat
dna integrity checkpoint GO:0031570 71 0.257
Mouse Fly
ventricular cardiac muscle cell differentiation GO:0055012 1 0.253
Rat
microtubule polymerization or depolymerization GO:0031109 37 0.253
cardiovascular system development GO:0072358 262 0.251
Rat
reproductive process GO:0022414 106 0.245
Worm Fly
regulation of kinase activity GO:0043549 314 0.243
Worm
female gamete generation GO:0007292 2 0.234
Worm Fly
microtubule anchoring GO:0034453 24 0.234
centrosome duplication GO:0051298 28 0.222
cell fate commitment GO:0045165 27 0.220
Fly
proteasomal protein catabolic process GO:0010498 176 0.220
regulation of microtubule polymerization or depolymerization GO:0031110 27 0.217
microtubule depolymerization GO:0007019 18 0.215
protein ubiquitination GO:0016567 314 0.213
meiotic cell cycle GO:0051321 13 0.203
Yeast Worm Fly
regulation of cyclin dependent protein serine threonine kinase activity GO:0000079 36 0.202
single organism cellular localization GO:1902580 332 0.202
Rat
peptidyl serine phosphorylation GO:0018105 101 0.202
negative regulation of cell cycle phase transition GO:1901988 89 0.201
Mouse Fly
embryo development GO:0009790 123 0.200
Worm
regulation of transferase activity GO:0051338 355 0.197
Worm
mitotic cell cycle checkpoint GO:0007093 68 0.195
Mouse Fly
mrna processing GO:0006397 133 0.186
Yeast
peptidyl threonine phosphorylation GO:0018107 41 0.186
response to oxygen containing compound GO:1901700 369 0.184
Rat
generation of neurons GO:0048699 152 0.179
Fly
positive regulation of cellular component organization GO:0051130 376 0.177
Yeast Worm
positive regulation of phosphorylation GO:0042327 394 0.174
Worm
negative regulation of phosphorylation GO:0042326 174 0.172
ribonucleoside monophosphate catabolic process GO:0009158 158 0.166
negative regulation of developmental process GO:0051093 247 0.163
regulation of mitosis GO:0007088 63 0.161
mitotic spindle stabilization GO:0043148 2 0.161
dna conformation change GO:0071103 113 0.161
Rat
response to abiotic stimulus GO:0009628 336 0.158
regulation of cytokinesis GO:0032465 45 0.156
mitotic spindle elongation GO:0000022 4 0.156
spindle elongation GO:0051231 4 0.155
ribonucleotide catabolic process GO:0009261 405 0.154
negative regulation of chromosome organization GO:2001251 48 0.151
Yeast
meiotic nuclear division GO:0007126 10 0.149
Yeast Worm Fly
rna processing GO:0006396 255 0.148
Yeast
cellular protein complex assembly GO:0043623 188 0.147
purine nucleoside catabolic process GO:0006152 398 0.146
mitotic spindle midzone assembly GO:0051256 4 0.145
positive regulation of chromosome segregation GO:0051984 9 0.144
dna packaging GO:0006323 77 0.142
Rat
negative regulation of mitotic metaphase anaphase transition GO:0045841 17 0.141
organophosphate catabolic process GO:0046434 430 0.140
cell development GO:0048468 328 0.138
Rat Worm Fly
regulation of cellular amine metabolic process GO:0033238 11 0.137
digestive tract development GO:0048565 75 0.135
cellular response to endogenous stimulus GO:0071495 336 0.134
nucleoside catabolic process GO:0009164 408 0.134
negative regulation of protein depolymerization GO:1901880 17 0.132
positive regulation of cytokinesis GO:0032467 29 0.129
macromolecular complex disassembly GO:0032984 60 0.126
purine ribonucleotide catabolic process GO:0009154 404 0.125
cellular macromolecular complex assembly GO:0034622 324 0.124
regulation of protein localization GO:0032880 296 0.124
Yeast Rat Fly
purine nucleoside triphosphate metabolic process GO:0009144 412 0.123
response to toxic substance GO:0009636 37 0.122
Rat
reproduction GO:0000003 63 0.120
Yeast Worm Fly
positive regulation of catabolic process GO:0009896 310 0.120
Yeast
regulation of mitotic sister chromatid segregation GO:0033047 27 0.119
glycerolipid catabolic process GO:0046503 18 0.117
Yeast
purine ribonucleoside metabolic process GO:0046128 437 0.116
cellular response to oxygen containing compound GO:1901701 276 0.115
Rat
nucleotide catabolic process GO:0009166 408 0.115
chromosome condensation GO:0030261 15 0.114
Rat
ribonucleoside catabolic process GO:0042454 406 0.113
cellular protein catabolic process GO:0044257 261 0.112
negative regulation of cytoskeleton organization GO:0051494 45 0.110
regulation of protein catabolic process GO:0042176 155 0.110
peptidyl serine modification GO:0018209 106 0.110
regulation of cell division GO:0051302 116 0.108
Yeast Worm
regulation of protein stability GO:0031647 87 0.107
regulation of protein dephosphorylation GO:0035304 18 0.106
oocyte development GO:0048599 1 0.104
Worm
negative regulation of mitotic anaphase promoting complex activity GO:0060564 4 0.104
maintenance of protein location GO:0045185 57 0.103
response to hormone GO:0009725 175 0.101
microtubule based movement GO:0007018 32 0.100
epithelium development GO:0060429 227 0.099
cellular protein complex disassembly GO:0043624 36 0.098
mitotic sister chromatid separation GO:0051306 18 0.097
regulation of striated muscle tissue development GO:0016202 26 0.097
Rat
ras protein signal transduction GO:0007265 73 0.096
Human
nucleoside triphosphate metabolic process GO:0009141 422 0.095
oocyte differentiation GO:0009994 2 0.094
Worm
regulation of meiosis GO:0040020 3 0.094
Worm
oogenesis GO:0048477 2 0.093
Worm Fly
purine ribonucleoside catabolic process GO:0046130 398 0.092
cellular response to dna damage stimulus GO:0006974 379 0.091
Yeast Mouse Fly
positive regulation of cytoskeleton organization GO:0051495 83 0.091
Yeast
dna replication GO:0006260 116 0.089
Yeast Rat
regulation of protein depolymerization GO:1901879 22 0.088
regulation of phosphatase activity GO:0010921 81 0.086
purine containing compound catabolic process GO:0072523 411 0.086
regulation of peptidase activity GO:0052547 180 0.086
ribonucleoside triphosphate metabolic process GO:0009199 412 0.086
mitotic spindle organization GO:0007052 27 0.086
negative regulation of hydrolase activity GO:0051346 182 0.083
metaphase plate congression GO:0051310 18 0.082
negative regulation of protein modification process GO:0031400 200 0.081
meiotic chromosome segregation GO:0045132 4 0.080
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.078
immune system development GO:0002520 195 0.078
purine nucleotide catabolic process GO:0006195 405 0.078
histone phosphorylation GO:0016572 16 0.075
Human Rat
developmental process involved in reproduction GO:0003006 66 0.075
Worm Fly
negative regulation of phosphatase activity GO:0010923 61 0.075
negative regulation of cellular protein metabolic process GO:0032269 353 0.074
ribonucleoside triphosphate catabolic process GO:0009203 391 0.074
positive regulation of kinase activity GO:0033674 204 0.073
Worm
regulation of cellular amino acid metabolic process GO:0006521 6 0.073
regulation of dna repair GO:0006282 47 0.072
Yeast
negative regulation of mitotic cell cycle phase transition GO:1901991 85 0.071
Mouse Fly
regulation of intracellular protein transport GO:0033157 123 0.071
Rat
histone h3 s10 phosphorylation GO:0043987 3 0.070
apoptotic signaling pathway GO:0097190 268 0.070
protein localization to organelle GO:0033365 280 0.069
mitotic dna integrity checkpoint GO:0044774 30 0.068
Mouse Fly
negative regulation of intracellular signal transduction GO:1902532 183 0.067
response to organic cyclic compound GO:0014070 204 0.066
Rat
protein dephosphorylation GO:0006470 81 0.065
embryo development ending in birth or egg hatching GO:0009792 34 0.063
Worm
response to metal ion GO:0010038 84 0.060
Rat
signal transduction by phosphorylation GO:0023014 297 0.060
regulation of nucleoside metabolic process GO:0009118 209 0.058
multi organism reproductive process GO:0044703 54 0.058
Worm Fly
cellular response to hormone stimulus GO:0032870 125 0.058
spindle checkpoint GO:0031577 26 0.058
positive regulation of heart growth GO:0060421 2 0.057
Rat
positive regulation of cell differentiation GO:0045597 211 0.055
establishment of organelle localization GO:0051656 59 0.055
Worm
atp catabolic process GO:0006200 157 0.055
regulation of muscle tissue development GO:1901861 26 0.054
Rat
vesicle mediated transport GO:0016192 371 0.053
Yeast
ribosome assembly GO:0042255 9 0.052
neuron differentiation GO:0030182 138 0.052
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.052
regulation of growth GO:0040008 165 0.051
Yeast Rat
protein polyubiquitination GO:0000209 110 0.051
intrinsic apoptotic signaling pathway GO:0097193 127 0.051
actin cytoskeleton organization GO:0030036 207 0.051
nucleoside monophosphate metabolic process GO:0009123 191 0.050
asymmetric neuroblast division GO:0055059 1 0.050
Fly
regulation of protein serine threonine kinase activity GO:0071900 179 0.048
Worm
striated muscle tissue development GO:0014706 59 0.048
Rat
positive regulation of cellular catabolic process GO:0031331 284 0.047
Yeast
purine nucleoside monophosphate metabolic process GO:0009126 186 0.046
positive regulation of lipid catabolic process GO:0050996 13 0.046
Yeast
positive regulation of chromosome organization GO:2001252 41 0.045
nucleoside triphosphate catabolic process GO:0009143 394 0.045
cyclin catabolic process GO:0008054 6 0.044
cellular ketone metabolic process GO:0042180 80 0.044
regulation of cardiac muscle cell proliferation GO:0060043 4 0.044
Rat
positive regulation of striated muscle tissue development GO:0045844 7 0.043
Rat
regulation of metaphase anaphase transition of cell cycle GO:1902099 26 0.043
microtubule bundle formation GO:0001578 15 0.042
centrosome separation GO:0051299 3 0.042
negative regulation of microtubule depolymerization GO:0007026 12 0.042
glycosyl compound catabolic process GO:1901658 413 0.042
positive regulation of transferase activity GO:0051347 227 0.042
Worm
positive regulation of proteolysis GO:0045862 142 0.041
tissue regeneration GO:0042246 3 0.041
meiotic cell cycle process GO:1903046 8 0.041
Yeast
sex differentiation GO:0007548 45 0.040
Worm
developmental maturation GO:0021700 28 0.040
Worm
regulation of proteolysis GO:0030162 293 0.039
cellular response to oxygen levels GO:0071453 55 0.039
purine nucleoside monophosphate catabolic process GO:0009128 158 0.039
positive regulation of programmed cell death GO:0043068 249 0.039
regulation of mitotic cell cycle phase transition GO:1901990 118 0.038
Mouse Fly
endocytosis GO:0006897 159 0.038
hematopoietic or lymphoid organ development GO:0048534 186 0.038
regulation of cellular ketone metabolic process GO:0010565 50 0.038
response to inorganic substance GO:0010035 127 0.037
Rat
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.037
positive regulation of organ growth GO:0046622 2 0.037
Rat
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.037
regulation of embryonic development GO:0045995 20 0.037
regulation of mitotic metaphase anaphase transition GO:0030071 26 0.036
negative regulation of chromosome segregation GO:0051985 18 0.036
Yeast
centrosome cycle GO:0007098 32 0.036
single organism reproductive process GO:0044702 98 0.036
Worm Fly
actin filament based process GO:0030029 224 0.036
positive regulation of dna replication GO:0045740 35 0.036
Yeast Rat
regulation of centrosome cycle GO:0046605 15 0.036
muscle cell development GO:0055001 29 0.035
Rat
positive regulation of developmental growth GO:0048639 16 0.035
Rat
gonad development GO:0008406 34 0.035
Worm
regulation of double strand break repair GO:2000779 22 0.035
Yeast
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 91 0.035
regulation of heart growth GO:0060420 4 0.034
Rat
regulation of cellular component biogenesis GO:0044087 281 0.034
negative regulation of protein metabolic process GO:0051248 391 0.034
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.034
microtubule cytoskeleton organization involved in mitosis GO:1902850 15 0.034
cellular response to metal ion GO:0071248 43 0.033
growth GO:0040007 202 0.033
Yeast Rat
nucleoside monophosphate catabolic process GO:0009125 159 0.033
cell morphogenesis GO:0000902 296 0.033
negative regulation of cell death GO:0060548 345 0.033
myeloid cell differentiation GO:0030099 117 0.033
single organism membrane organization GO:0044802 268 0.032
negative regulation of protein phosphorylation GO:0001933 140 0.032
protein catabolic process GO:0030163 325 0.031
cellular response to lipid GO:0071396 127 0.031
regulation of nucleotide metabolic process GO:0006140 269 0.031
reproductive structure development GO:0048608 55 0.031
Worm
regulation of intracellular transport GO:0032386 195 0.031
Rat
peptidyl threonine modification GO:0018210 45 0.030
regulation of purine nucleotide metabolic process GO:1900542 264 0.030
male meiosis GO:0007140 1 0.030
Fly
metaphase anaphase transition of mitotic cell cycle GO:0007091 21 0.030
regulation of small gtpase mediated signal transduction GO:0051056 156 0.030
maintenance of location in cell GO:0051651 62 0.030
cellular response to hypoxia GO:0071456 51 0.029
maintenance of protein location in cell GO:0032507 56 0.029
regulation of muscle organ development GO:0048634 27 0.029
Rat
neurogenesis GO:0022008 169 0.029
Fly
negative regulation of protein complex disassembly GO:0043242 20 0.029
response to fatty acid GO:0070542 13 0.029
positive regulation of hydrolase activity GO:0051345 331 0.028
mitotic metaphase plate congression GO:0007080 14 0.028
negative regulation of proteolysis GO:0045861 132 0.028
negative regulation of mitotic cell cycle GO:0045930 102 0.028
Yeast Mouse Fly
digestive system development GO:0055123 75 0.028
anatomical structure formation involved in morphogenesis GO:0048646 284 0.027
Fly
positive regulation of histone phosphorylation GO:0033129 3 0.027
regulation of binding GO:0051098 111 0.027
positive regulation of fibroblast proliferation GO:0048146 21 0.026
cellular component morphogenesis GO:0032989 314 0.026
cardiac muscle cell differentiation GO:0055007 15 0.026
Rat
positive regulation of apoptotic process GO:0043065 246 0.026
nuclear import GO:0051170 106 0.026
Rat
ribonucleoside monophosphate metabolic process GO:0009161 187 0.026
tube morphogenesis GO:0035239 95 0.026
regulation of nucleocytoplasmic transport GO:0046822 98 0.026
Rat
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 71 0.026
neuromuscular junction development GO:0007528 3 0.025
regulation of cellular protein catabolic process GO:1903362 96 0.025
positive regulation of dna dependent dna replication GO:2000105 7 0.025
Yeast
negative regulation of cell differentiation GO:0045596 171 0.024
positive regulation of response to dna damage stimulus GO:2001022 43 0.024
regulation of cytoplasmic transport GO:1903649 149 0.024
Rat
positive regulation of cardiac muscle tissue growth GO:0055023 2 0.024
Rat
positive regulation of intracellular protein transport GO:0090316 76 0.023
Rat
positive regulation of cellular amine metabolic process GO:0033240 7 0.023
regulation of protein transport GO:0051223 213 0.023
Rat
regulation of purine nucleotide catabolic process GO:0033121 205 0.023
regulation of chromatin modification GO:1903308 51 0.023
regulation of ras protein signal transduction GO:0046578 155 0.023
wnt signaling pathway GO:0016055 156 0.022
response to oxidative stress GO:0006979 121 0.022
Rat
multicellular organism reproduction GO:0032504 42 0.022
Worm Fly
positive regulation of triglyceride metabolic process GO:0090208 9 0.022
Yeast
regulation of fibroblast proliferation GO:0048145 32 0.022
chordate embryonic development GO:0043009 34 0.022
mapk cascade GO:0000165 288 0.022
mature ribosome assembly GO:0042256 5 0.022
cofactor metabolic process GO:0051186 87 0.021
endomembrane system organization GO:0010256 196 0.021
multicellular organismal reproductive process GO:0048609 40 0.021
Worm Fly
receptor mediated endocytosis GO:0006898 84 0.021
cardiac muscle cell proliferation GO:0060038 6 0.021
Rat
regulation of apoptotic signaling pathway GO:2001233 175 0.021
negative regulation of programmed cell death GO:0043069 321 0.021
stem cell proliferation GO:0072089 25 0.021
Fly
spermatogenesis GO:0007283 22 0.021
Fly
cell cell signaling GO:0007267 155 0.020
actomyosin structure organization GO:0031032 59 0.020
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.020
positive regulation of mitosis GO:0045840 25 0.020
sister chromatid segregation GO:0000819 54 0.020
regulation of centrosome duplication GO:0010824 14 0.020
negative regulation of apoptotic process GO:0043066 316 0.020
cellular amine metabolic process GO:0044106 41 0.020
epithelial cell differentiation GO:0030855 141 0.019
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.019
regulation of chromatin binding GO:0035561 3 0.019
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.019
response to lipid GO:0033993 206 0.019
cell junction assembly GO:0034329 67 0.019
regulation of establishment of protein localization GO:0070201 242 0.018
Rat
positive regulation of cytoplasmic transport GO:1903651 82 0.018
Rat
protein tetramerization GO:0051262 47 0.018
cellular amino acid metabolic process GO:0006520 116 0.018
regulation of dna metabolic process GO:0051052 153 0.018
Yeast Rat
mitotic centrosome separation GO:0007100 1 0.018
cell morphogenesis involved in differentiation GO:0000904 144 0.018
positive regulation of nucleotide metabolic process GO:0045981 230 0.018
reproductive system development GO:0061458 56 0.017
Worm
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.017
response to organonitrogen compound GO:0010243 156 0.017
Rat
cytokinetic process GO:0032506 12 0.017
oxidation reduction process GO:0055114 396 0.017
positive regulation of nucleotide catabolic process GO:0030813 185 0.017
negative regulation of protein processing GO:0010955 142 0.017
dna catabolic process exonucleolytic GO:0000738 17 0.017
Yeast
heart development GO:0007507 95 0.017
Rat
negative regulation of transcription initiation from rna polymerase ii promoter GO:0060633 3 0.017
positive regulation of dna metabolic process GO:0051054 73 0.017
Yeast Rat
regulation of microtubule depolymerization GO:0031114 12 0.016
regulation of endopeptidase activity GO:0052548 170 0.016
positive regulation of mrna processing GO:0050685 17 0.016
protein oligomerization GO:0051259 173 0.016
nucleic acid phosphodiester bond hydrolysis GO:0090305 102 0.016
Yeast
cellular response to organic cyclic compound GO:0071407 127 0.016
protein localization to chromosome GO:0034502 30 0.016
positive regulation of nuclear division GO:0051785 27 0.016
Worm
clearance of foreign intracellular dna by conversion of dna cytidine to uridine GO:0044356 1 0.016
positive regulation of mitotic cell cycle phase transition GO:1901992 19 0.016
regulation of mapk cascade GO:0043408 262 0.016
regulation of chromosome organization GO:0033044 103 0.016
Yeast
male gamete generation GO:0048232 22 0.016
Fly
response to nitrogen compound GO:1901698 184 0.015
Rat
sexual reproduction GO:0019953 37 0.015
Worm Fly
erythrocyte homeostasis GO:0034101 31 0.015
positive regulation of protein transport GO:0051222 135 0.015
Rat
regulation of cellular respiration GO:0043457 4 0.015
determination of adult lifespan GO:0008340 2 0.015
cellular response to decreased oxygen levels GO:0036294 51 0.015
response to light stimulus GO:0009416 87 0.015
mitotic dna damage checkpoint GO:0044773 28 0.015
Mouse Fly
regulation of protein complex disassembly GO:0043244 28 0.015
peptidyl tyrosine phosphorylation GO:0018108 170 0.015
cell maturation GO:0048469 11 0.014
Worm
positive regulation of transport GO:0051050 336 0.014
Rat
regulation of proteasomal protein catabolic process GO:0061136 87 0.014
cellular lipid metabolic process GO:0044255 303 0.014
Yeast
response to radiation GO:0009314 151 0.014
regulation of histone modification GO:0031056 47 0.014
regulation of mrna metabolic process GO:1903311 53 0.014
positive regulation of nucleoside metabolic process GO:0045979 186 0.013
response to oxygen levels GO:0070482 100 0.013
guanosine containing compound metabolic process GO:1901068 244 0.013
gland development GO:0048732 48 0.013
neuron development GO:0048666 113 0.013
chromosome separation GO:0051304 23 0.013
cytoplasmic transport GO:0016482 379 0.013
Rat
organophosphate biosynthetic process GO:0090407 163 0.013
muscle organ development GO:0007517 56 0.013
Rat
negative regulation of cellular catabolic process GO:0031330 83 0.013
regulation of stress activated protein kinase signaling cascade GO:0070302 85 0.013
regulation of mitotic sister chromatid separation GO:0010965 27 0.013
positive regulation of intracellular transport GO:0032388 104 0.013
Rat
mitotic chromosome condensation GO:0007076 11 0.013
action potential GO:0001508 34 0.013
cardiac muscle tissue growth GO:0055017 6 0.013
Rat
immune response GO:0006955 307 0.013
regulation of nucleotide catabolic process GO:0030811 205 0.013
mitotic spindle checkpoint GO:0071174 18 0.013
cellular response to inorganic substance GO:0071241 45 0.012
cellular response to abiotic stimulus GO:0071214 117 0.012
positive regulation of cardiac muscle tissue development GO:0055025 6 0.012
Rat
coenzyme metabolic process GO:0006732 65 0.012
cell part morphogenesis GO:0032990 137 0.012
dna damage checkpoint GO:0000077 68 0.012
Mouse Fly
cell type specific apoptotic process GO:0097285 125 0.012
secretion GO:0046903 254 0.012
regulation of cell morphogenesis GO:0022604 153 0.012
response to organophosphorus GO:0046683 41 0.012
cellular process involved in reproduction in multicellular organism GO:0022412 15 0.012
Worm Fly
regulation of homeostatic process GO:0032844 121 0.012
regulation of protein ubiquitination GO:0031396 95 0.012
positive regulation of muscle organ development GO:0048636 7 0.012
Rat
cellular response to fatty acid GO:0071398 8 0.012
regulation of intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediator GO:1902165 7 0.012
cell cycle arrest GO:0007050 71 0.011
regulation of wnt signaling pathway GO:0030111 123 0.011
regulation of cysteine type endopeptidase activity GO:2000116 127 0.011
mitotic g2 dna damage checkpoint GO:0007095 7 0.011
Mouse Fly
protein processing GO:0016485 226 0.011
regulation of dna replication GO:0006275 68 0.011
Yeast Rat
regulation of dendritic cell chemotaxis GO:2000508 4 0.011
positive regulation of muscle tissue development GO:1901863 7 0.011
Rat
guanosine containing compound catabolic process GO:1901069 239 0.011
response to hypoxia GO:0001666 96 0.011
positive regulation of growth GO:0045927 58 0.011
Rat
negative regulation of protein maturation GO:1903318 142 0.011
regulation of chromatin organization GO:1902275 56 0.011
response to decreased oxygen levels GO:0036293 96 0.011
regulation of myeloid cell differentiation GO:0045637 81 0.010
cytokinesis completion of separation GO:0007109 3 0.010
exit from mitosis GO:0010458 10 0.010
muscle cell differentiation GO:0042692 63 0.010
Rat
negative regulation of catabolic process GO:0009895 104 0.010
actomyosin contractile ring organization GO:0044837 1 0.010
cardiac muscle tissue development GO:0048738 39 0.010
Rat
metaphase anaphase transition of cell cycle GO:0044784 21 0.010

CDK1 disease predictions

Disease DO term ID Size Probability Func Analog Org
immune system disease DOID:2914 155 0.029