IMP
Process View
negative regulation of mitotic anaphase promoting complex activity
Any process that decreases the rate frequency or extent of anaphase-promoting complex activity regulating the mitotic cell cycle.
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In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "negative regulation of mitotic anaphase promoting complex activity"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| CDK2 | cyclin-dependent kinase 2 | 1.000 | ||
| CCNA2 | cyclin A2 | 0.999 | ||
| CCNB1 | cyclin B1 | 0.999 | ||
| CDC20 | cell division cycle 20 homolog (S. cerevisiae) | 0.999 | ||
| SKP2 | S-phase kinase-associated protein 2 (p45) | 0.998 | ||
| CDC27 | cell division cycle 27 homolog (S. cerevisiae) | 0.998 | ||
| FOXM1 | forkhead box M1 | 0.986 | ||
| CKS1B | CDC28 protein kinase regulatory subunit 1B | 0.972 | ||
| CCNE2 | cyclin E2 | 0.906 | Fly | |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | 0.894 | ||
| UHRF2 | ubiquitin-like with PHD and ring finger domains 2 | 0.886 | ||
| CDT1 | chromatin licensing and DNA replication factor 1 | 0.882 | ||
| BUB1B | budding uninhibited by benzimidazoles 1 homolog beta (yeast) | 0.847 | ||
| CDC6 | cell division cycle 6 homolog (S. cerevisiae) | 0.796 | ||
| CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | 0.708 | ||
| FBXO5 | F-box protein 5 | 0.590 | ||
| CCND1 | cyclin D1 | 0.578 | ||
| ANAPC4 | anaphase promoting complex subunit 4 | 0.467 | ||
| CCNB2 | cyclin B2 | 0.454 | ||
| RBL1 | retinoblastoma-like 1 (p107) | 0.438 | ||
| CDKN3 | cyclin-dependent kinase inhibitor 3 | 0.317 | ||
| CDC26 | cell division cycle 26 homolog (S. cerevisiae) | 0.300 | ||
| CKS2 | CDC28 protein kinase regulatory subunit 2 | 0.276 | ||
| CDC25A | cell division cycle 25 homolog A (S. pombe) | 0.205 | ||
| FBXW7 | F-box and WD repeat domain containing 7 | 0.198 | ||
| ORC1 | origin recognition complex, subunit 1 | 0.195 | ||
| ANAPC11 | anaphase promoting complex subunit 11 | 0.185 | ||
| GMNN | geminin, DNA replication inhibitor | 0.172 | ||
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) | 0.157 | ||
| REV3L | REV3-like, catalytic subunit of DNA polymerase zeta (yeast) | 0.124 | ||
| TFDP1 | transcription factor Dp-1 | 0.116 | ||
| ADAM9 | ADAM metallopeptidase domain 9 | 0.115 | ||
| MAD2L2 | MAD2 mitotic arrest deficient-like 2 (yeast) | 0.109 | ||
| CDK1 | cyclin-dependent kinase 1 | 0.104 | ||
| RB1 | retinoblastoma 1 | 0.101 | ||
| CCNE1 | cyclin E1 | 0.100 | Fly | |
| ANAPC7 | anaphase promoting complex subunit 7 | 0.096 | ||
| MAD1L1 | MAD1 mitotic arrest deficient-like 1 (yeast) | 0.088 | ||
| ANAPC5 | anaphase promoting complex subunit 5 | 0.083 | ||
| MAD2L1 | MAD2 mitotic arrest deficient-like 1 (yeast) | 0.076 | ||
| SKP1 | S-phase kinase-associated protein 1 | 0.076 | ||
| CDC23 | cell division cycle 23 homolog (S. cerevisiae) | 0.067 | ||
| MKRN1 | makorin ring finger protein 1 | 0.062 | ||
| PRC1 | protein regulator of cytokinesis 1 | 0.057 | ||
| ZNF828 | zinc finger protein 828 | 0.049 | ||
| RBBP8 | retinoblastoma binding protein 8 | 0.049 | ||
| CCND2 | cyclin D2 | 0.046 | ||
| E2F1 | E2F transcription factor 1 | 0.046 | ||
| ADAM17 | ADAM metallopeptidase domain 17 | 0.040 | ||
| TTK | TTK protein kinase | 0.037 | ||
| SLBP | stem-loop binding protein | 0.036 | ||
| TRIP13 | thyroid hormone receptor interactor 13 | 0.035 | ||
| MAD2L1BP | MAD2L1 binding protein | 0.029 | ||
| MCM6 | minichromosome maintenance complex component 6 | 0.029 | ||
| ANKRD52 | ankyrin repeat domain 52 | 0.028 | ||
| HSPB11 | heat shock protein family B (small), member 11 | 0.028 | ||
| CCND3 | cyclin D3 | 0.027 | ||
| ATAD2 | ATPase family, AAA domain containing 2 | 0.027 | ||
| HERC2 | hect domain and RLD 2 | 0.027 | ||
| CENPQ | centromere protein Q | 0.024 | ||
| GGH | gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) | 0.022 | ||
| CLSPN | claspin | 0.021 | ||
| CCNA1 | cyclin A1 | 0.020 | ||
| C13orf27 | chromosome 13 open reading frame 27 | 0.020 | ||
| DBF4 | DBF4 homolog (S. cerevisiae) | 0.020 | ||
| DCK | deoxycytidine kinase | 0.019 | ||
| EVI5 | ecotropic viral integration site 5 | 0.017 | ||
| CDK6 | cyclin-dependent kinase 6 | 0.017 | ||
| ANAPC1 | anaphase promoting complex subunit 1 | 0.016 | ||
| BTRC | beta-transducin repeat containing | 0.016 | ||
| USP44 | ubiquitin specific peptidase 44 | 0.014 | ||
| CDC7 | cell division cycle 7 homolog (S. cerevisiae) | 0.014 | ||
| NPAT | nuclear protein, ataxia-telangiectasia locus | 0.014 | ||
| PTEN | phosphatase and tensin homolog | 0.014 | ||
| HMGB1 | high mobility group box 1 | 0.013 | ||
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | 0.013 | ||
| SRRM2 | serine/arginine repetitive matrix 2 | 0.012 | ||
| ACYP1 | acylphosphatase 1, erythrocyte (common) type | 0.012 | ||
| CDC16 | cell division cycle 16 homolog (S. cerevisiae) | 0.011 | ||
| ZNF367 | zinc finger protein 367 | 0.011 |