|
|
regulation of transforming growth factor beta receptor signaling pathway
|
GO:0017015 |
48 |
0.892
|
|
|
|
response to host
|
GO:0075136 |
2 |
0.828
|
|
|
|
negative regulation of androgen receptor activity
|
GO:2000824 |
2 |
0.769
|
|
|
|
response to host defenses
|
GO:0052200 |
2 |
0.754
|
|
|
|
evasion or tolerance of host defenses by virus
|
GO:0019049 |
2 |
0.746
|
|
|
|
negative regulation of gliogenesis
|
GO:0014014 |
3 |
0.702
|
|
|
|
atrioventricular valve development
|
GO:0003171 |
3 |
0.689
|
|
|
|
negative regulation of sodium ion transmembrane transport
|
GO:1902306 |
2 |
0.674
|
|
|
|
negative regulation of transcription initiation from rna polymerase ii promoter
|
GO:0060633 |
3 |
0.645
|
|
|
|
ventricular septum morphogenesis
|
GO:0060412 |
3 |
0.643
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.635
|
|
|
|
negative regulation of glial cell proliferation
|
GO:0060253 |
2 |
0.626
|
|
|
|
endocardial cushion development
|
GO:0003197 |
3 |
0.585
|
|
|
|
cardiac epithelial to mesenchymal transition
|
GO:0060317 |
3 |
0.584
|
|
|
|
positive regulation of osteoblast differentiation
|
GO:0045669 |
23 |
0.583
|
|
|
|
retinal ganglion cell axon guidance
|
GO:0031290 |
2 |
0.571
|
|
|
|
cell fate determination
|
GO:0001709 |
3 |
0.562
|
|
|
|
mesenchymal cell development
|
GO:0014031 |
50 |
0.541
|
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.540
|
|
|
|
evasion or tolerance of host defenses
|
GO:0044415 |
2 |
0.537
|
|
|
|
cellular response to transforming growth factor beta stimulus
|
GO:0071560 |
94 |
0.532
|
|
|
|
regulation of activin receptor signaling pathway
|
GO:0032925 |
14 |
0.527
|
|
|
|
positive regulation of mesenchymal stem cell differentiation
|
GO:2000741 |
4 |
0.475
|
|
|
|
smad protein complex assembly
|
GO:0007183 |
12 |
0.470
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.460
|
|
|
|
receptor catabolic process
|
GO:0032801 |
11 |
0.451
|
|
|
|
stem cell development
|
GO:0048864 |
69 |
0.450
|
|
|
|
regulation of ketone biosynthetic process
|
GO:0010566 |
7 |
0.441
|
|
|
|
positive regulation of stem cell differentiation
|
GO:2000738 |
29 |
0.420
|
|
|
|
response to transforming growth factor beta
|
GO:0071559 |
94 |
0.417
|
|
|
|
transforming growth factor beta receptor signaling pathway
|
GO:0007179 |
76 |
0.409
|
|
|
|
regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090092 |
90 |
0.400
|
|
|
|
activin receptor signaling pathway
|
GO:0032924 |
24 |
0.379
|
|
|
|
atrioventricular valve morphogenesis
|
GO:0003181 |
2 |
0.377
|
|
|
|
epithelial to mesenchymal transition
|
GO:0001837 |
48 |
0.371
|
|
|
|
regulation of mrna export from nucleus
|
GO:0010793 |
3 |
0.366
|
|
|
|
lipid metabolic process
|
GO:0006629 |
381 |
0.333
|
|
|
|
endodermal cell fate commitment
|
GO:0001711 |
4 |
0.321
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.319
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
125 |
0.314
|
|
|
|
regulation of stem cell differentiation
|
GO:2000736 |
56 |
0.304
|
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
142 |
0.303
|
|
|
|
regulation of ossification
|
GO:0030278 |
58 |
0.303
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.295
|
|
|
|
regulation of osteoblast differentiation
|
GO:0045667 |
38 |
0.286
|
|
|
|
zygotic specification of dorsal ventral axis
|
GO:0007352 |
2 |
0.282
|
|
|
|
ubiquitin dependent endocytosis
|
GO:0070086 |
1 |
0.272
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
342 |
0.265
|
|
|
|
cell proliferation involved in heart valve development
|
GO:2000793 |
1 |
0.250
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.245
|
|
|
|
stem cell differentiation
|
GO:0048863 |
93 |
0.242
|
|
|
|
osteoblast differentiation
|
GO:0001649 |
92 |
0.242
|
|
|
|
regulation of pathway restricted smad protein phosphorylation
|
GO:0060393 |
34 |
0.236
|
|
|
|
regulation of cellular response to growth factor stimulus
|
GO:0090287 |
76 |
0.235
|
|
|
|
cellular potassium ion transport
|
GO:0071804 |
60 |
0.229
|
|
|
|
neuron fate commitment
|
GO:0048663 |
2 |
0.226
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.223
|
|
|
|
negative regulation of sequence specific dna binding transcription factor activity
|
GO:0043433 |
89 |
0.220
|
|
|
|
negative regulation of pathway restricted smad protein phosphorylation
|
GO:0060394 |
11 |
0.219
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
303 |
0.218
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.217
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
211 |
0.212
|
|
|
|
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090101 |
45 |
0.208
|
|
|
|
negative regulation of sodium ion transmembrane transporter activity
|
GO:2000650 |
2 |
0.206
|
|
|
|
avoidance of defenses of other organism involved in symbiotic interaction
|
GO:0051832 |
2 |
0.204
|
|
|
|
segmentation
|
GO:0035282 |
4 |
0.202
|
|
|
|
somatic stem cell maintenance
|
GO:0035019 |
4 |
0.201
|
|
|
|
potassium ion transmembrane transport
|
GO:0071805 |
60 |
0.200
|
|
|
|
anterior posterior axis specification
|
GO:0009948 |
2 |
0.199
|
|
|
|
response to growth factor
|
GO:0070848 |
205 |
0.199
|
|
|
|
protein ubiquitination
|
GO:0016567 |
314 |
0.199
|
|
|
|
heart development
|
GO:0007507 |
95 |
0.194
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
195 |
0.186
|
|
|
|
mesenchyme development
|
GO:0060485 |
59 |
0.184
|
|
|
|
coenzyme metabolic process
|
GO:0006732 |
65 |
0.184
|
|
|
|
ribosomal large subunit export from nucleus
|
GO:0000055 |
3 |
0.181
|
|
|
|
positive regulation of canonical wnt signaling pathway
|
GO:0090263 |
33 |
0.181
|
|
|
|
negative regulation of transforming growth factor beta receptor signaling pathway
|
GO:0030512 |
28 |
0.181
|
|
|
|
urogenital system development
|
GO:0001655 |
65 |
0.172
|
|
|
|
regulation of isoprenoid metabolic process
|
GO:0019747 |
1 |
0.172
|
|
|
|
positive regulation of male gonad development
|
GO:2000020 |
3 |
0.169
|
|
|
|
transmission of virus
|
GO:0019089 |
1 |
0.168
|
|
|
|
positive regulation of bmp signaling pathway
|
GO:0030513 |
9 |
0.168
|
|
|
|
negative regulation of cell growth
|
GO:0030308 |
83 |
0.165
|
|
|
|
ventricular cardiac muscle tissue morphogenesis
|
GO:0055010 |
14 |
0.161
|
|
|
|
cation transport
|
GO:0006812 |
331 |
0.159
|
|
|
|
positive regulation of epithelial to mesenchymal transition
|
GO:0010718 |
22 |
0.158
|
|
|
|
tube development
|
GO:0035295 |
125 |
0.153
|
|
|
|
epithelium development
|
GO:0060429 |
227 |
0.151
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.149
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.144
|
|
|
|
dolichol biosynthetic process
|
GO:0019408 |
1 |
0.142
|
|
|
|
bmp signaling pathway
|
GO:0030509 |
49 |
0.142
|
|
|
|
positive regulation of cell morphogenesis involved in differentiation
|
GO:0010770 |
50 |
0.141
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.140
|
|
|
|
trna export from nucleus
|
GO:0006409 |
1 |
0.140
|
|
|
|
symbiosis encompassing mutualism through parasitism
|
GO:0044403 |
156 |
0.138
|
|
|
|
heart morphogenesis
|
GO:0003007 |
48 |
0.138
|
|
|
|
mesenchymal cell differentiation
|
GO:0048762 |
52 |
0.138
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.137
|
|
|
|
regulation of nucleocytoplasmic transport
|
GO:0046822 |
98 |
0.137
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.136
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.135
|
|
|
|
cardiac chamber development
|
GO:0003205 |
30 |
0.135
|
|
|
|
positive regulation of protein catabolic process
|
GO:0045732 |
75 |
0.134
|
|
|
|
negative regulation of transcription from rna polymerase ii promoter
|
GO:0000122 |
281 |
0.133
|
|
|
|
response to other organism
|
GO:0051707 |
261 |
0.132
|
|
|
|
negative regulation of sodium ion transport
|
GO:0010766 |
3 |
0.130
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.124
|
|
|
|
renal system development
|
GO:0072001 |
63 |
0.123
|
|
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.123
|
|
|
|
regulation of cell growth
|
GO:0001558 |
135 |
0.120
|
|
|
|
vacuolar transport
|
GO:0007034 |
34 |
0.120
|
|
|
|
nodal signaling pathway involved in determination of left right asymmetry
|
GO:0038107 |
1 |
0.120
|
|
|
|
metal ion transport
|
GO:0030001 |
272 |
0.118
|
|
|
|
nodal signaling pathway involved in determination of lateral mesoderm left right asymmetry
|
GO:1900164 |
1 |
0.118
|
|
|
|
regulation of canonical wnt signaling pathway
|
GO:0060828 |
88 |
0.118
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.117
|
|
|
|
mesonephric epithelium development
|
GO:0072163 |
14 |
0.116
|
|
|
|
cardiac ventricle morphogenesis
|
GO:0003208 |
20 |
0.116
|
|
|
|
nuclear transport
|
GO:0051169 |
179 |
0.114
|
|
|
|
regulation of epithelial to mesenchymal transition
|
GO:0010717 |
37 |
0.114
|
|
|
|
lysosomal transport
|
GO:0007041 |
33 |
0.113
|
|
|
|
development involved in symbiotic interaction
|
GO:0044111 |
1 |
0.113
|
|
|
|
lipid biosynthetic process
|
GO:0008610 |
177 |
0.113
|
|
|
|
blood circulation
|
GO:0008015 |
113 |
0.113
|
|
|
|
trna transport
|
GO:0051031 |
1 |
0.112
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.111
|
|
|
|
regulation of potassium ion transmembrane transport
|
GO:1901379 |
20 |
0.109
|
|
|
|
neuron development
|
GO:0048666 |
113 |
0.109
|
|
|
|
positive regulation of cytoplasmic transport
|
GO:1903651 |
82 |
0.109
|
|
|
|
ribosomal subunit export from nucleus
|
GO:0000054 |
4 |
0.108
|
|
|
|
ribonucleoprotein complex localization
|
GO:0071166 |
4 |
0.107
|
|
|
|
regulation of ion transport
|
GO:0043269 |
189 |
0.107
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
176 |
0.107
|
|
|
|
common partner smad protein phosphorylation
|
GO:0007182 |
3 |
0.106
|
|
|
|
negative regulation of transcription from rna polymerase ii promoter in response to uv induced dna damage
|
GO:0010768 |
1 |
0.106
|
|
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.106
|
|
|
|
modulation by virus of host morphology or physiology
|
GO:0019048 |
10 |
0.106
|
|
|
|
regulation of glial cell proliferation
|
GO:0060251 |
4 |
0.104
|
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.104
|
|
|
|
interaction with host
|
GO:0051701 |
42 |
0.104
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
180 |
0.104
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
92 |
0.103
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
0.102
|
|
|
|
canonical wnt signaling pathway
|
GO:0060070 |
116 |
0.102
|
|
|
|
potassium ion transport
|
GO:0006813 |
62 |
0.102
|
|
|
|
immune response
|
GO:0006955 |
307 |
0.101
|
|
|
|
cardiac ventricle development
|
GO:0003231 |
23 |
0.101
|
|
|
|
sodium ion transmembrane transport
|
GO:0035725 |
59 |
0.100
|
|
|
|
digestive tract development
|
GO:0048565 |
75 |
0.099
|
|
|
|
muscle organ morphogenesis
|
GO:0048644 |
19 |
0.098
|
|
|
|
cation transmembrane transport
|
GO:0098655 |
238 |
0.096
|
|
|
|
evasion or tolerance of defenses of other organism involved in symbiotic interaction
|
GO:0051834 |
2 |
0.096
|
|
|
|
intracellular receptor signaling pathway
|
GO:0030522 |
104 |
0.096
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.095
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.094
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.093
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
156 |
0.093
|
Human |
|
|
inorganic ion transmembrane transport
|
GO:0098660 |
231 |
0.092
|
|
|
|
negative regulation of schwann cell proliferation
|
GO:0010626 |
1 |
0.091
|
|
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.091
|
|
|
|
tube morphogenesis
|
GO:0035239 |
95 |
0.091
|
|
|
|
modification by symbiont of host morphology or physiology
|
GO:0044003 |
12 |
0.090
|
|
|
|
chromatin assembly or disassembly
|
GO:0006333 |
78 |
0.089
|
|
|
|
growth
|
GO:0040007 |
202 |
0.088
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.088
|
|
|
|
rrna containing ribonucleoprotein complex export from nucleus
|
GO:0071428 |
4 |
0.088
|
|
|
|
cardiovascular system development
|
GO:0072358 |
262 |
0.088
|
|
|
|
polyprenol biosynthetic process
|
GO:0016094 |
1 |
0.087
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
149 |
0.087
|
|
|
|
negative regulation of transport
|
GO:0051051 |
176 |
0.086
|
|
|
|
transforming growth factor beta production
|
GO:0071604 |
14 |
0.086
|
|
|
|
regulation of rrna processing
|
GO:2000232 |
1 |
0.086
|
|
|
|
positive regulation of peptidase activity
|
GO:0010952 |
88 |
0.085
|
|
|
|
muscle contraction
|
GO:0006936 |
73 |
0.085
|
|
|
|
coenzyme biosynthetic process
|
GO:0009108 |
24 |
0.084
|
|
|
|
regulation of cell development
|
GO:0060284 |
161 |
0.083
|
|
|
|
monocarboxylic acid biosynthetic process
|
GO:0072330 |
67 |
0.083
|
|
|
|
kidney epithelium development
|
GO:0072073 |
25 |
0.083
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.082
|
|
|
|
organic acid biosynthetic process
|
GO:0016053 |
97 |
0.080
|
|
|
|
cardiac septum morphogenesis
|
GO:0060411 |
9 |
0.080
|
|
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.080
|
|
|
|
ion homeostasis
|
GO:0050801 |
230 |
0.080
|
|
|
|
kidney development
|
GO:0001822 |
53 |
0.079
|
|
|
|
regulation of endopeptidase activity
|
GO:0052548 |
170 |
0.079
|
|
|
|
regulation of male gonad development
|
GO:2000018 |
4 |
0.078
|
|
|
|
monovalent inorganic cation transport
|
GO:0015672 |
128 |
0.078
|
|
|
|
negative regulation of smad protein complex assembly
|
GO:0010991 |
4 |
0.078
|
|
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.078
|
|
|
|
carboxylic acid biosynthetic process
|
GO:0046394 |
97 |
0.078
|
|
|
|
cardiac muscle tissue morphogenesis
|
GO:0055008 |
18 |
0.078
|
|
|
|
cardiac septum development
|
GO:0003279 |
13 |
0.078
|
|
|
|
regulation of metal ion transport
|
GO:0010959 |
120 |
0.078
|
|
|
|
negative regulation of peptidyl threonine phosphorylation
|
GO:0010801 |
6 |
0.078
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.078
|
|
|
|
maintenance of location
|
GO:0051235 |
112 |
0.077
|
|
|
|
transmembrane transport
|
GO:0055085 |
399 |
0.077
|
|
|
|
negative regulation of bmp signaling pathway
|
GO:0030514 |
17 |
0.077
|
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
155 |
0.076
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.076
|
|
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.075
|
|
|
|
smooth muscle cell differentiation
|
GO:0051145 |
8 |
0.075
|
|
|
|
polyprenol metabolic process
|
GO:0016093 |
3 |
0.075
|
|
|
|
striated muscle contraction
|
GO:0006941 |
52 |
0.075
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.074
|
|
|
|
response to lipid
|
GO:0033993 |
206 |
0.074
|
|
|
|
endosome transport via multivesicular body sorting pathway
|
GO:0032509 |
3 |
0.074
|
|
|
|
positive regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043280 |
69 |
0.074
|
|
|
|
heart valve formation
|
GO:0003188 |
2 |
0.074
|
|
|
|
positive regulation of proteasomal protein catabolic process
|
GO:1901800 |
35 |
0.073
|
|
|
|
regulation of cell morphogenesis involved in differentiation
|
GO:0010769 |
83 |
0.073
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.073
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.073
|
|
|
|
ureteric bud development
|
GO:0001657 |
13 |
0.072
|
|
|
|
negative regulation of potassium ion transmembrane transporter activity
|
GO:1901017 |
3 |
0.072
|
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.072
|
|
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.072
|
|
|
|
ossification
|
GO:0001503 |
121 |
0.071
|
|
|
|
endodermal cell fate specification
|
GO:0001714 |
4 |
0.071
|
|
|
|
trna processing
|
GO:0008033 |
23 |
0.071
|
|
|
|
neuromuscular junction development
|
GO:0007528 |
3 |
0.071
|
|
|
|
interspecies interaction between organisms
|
GO:0044419 |
156 |
0.071
|
|
|
|
chemical homeostasis
|
GO:0048878 |
306 |
0.071
|
|
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
144 |
0.071
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.070
|
|
|
|
system process
|
GO:0003008 |
349 |
0.070
|
|
|
|
negative regulation of protein complex assembly
|
GO:0031333 |
43 |
0.070
|
|
|
|
regulation of epithelial cell migration
|
GO:0010632 |
93 |
0.070
|
|
|
|
ion transmembrane transport
|
GO:0034220 |
338 |
0.069
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.069
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.069
|
|
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.069
|
|
|
|
positive regulation of wnt signaling pathway
|
GO:0030177 |
54 |
0.068
|
|
|
|
sex determination
|
GO:0007530 |
3 |
0.068
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
162 |
0.068
|
|
|
|
muscle tissue morphogenesis
|
GO:0060415 |
19 |
0.067
|
|
|
|
progesterone receptor signaling pathway
|
GO:0050847 |
3 |
0.067
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.065
|
|
|
|
stem cell division
|
GO:0017145 |
2 |
0.065
|
|
|
|
monocarboxylic acid metabolic process
|
GO:0032787 |
185 |
0.065
|
|
|
|
late endosome to vacuole transport
|
GO:0045324 |
2 |
0.065
|
|
|
|
cofactor metabolic process
|
GO:0051186 |
87 |
0.064
|
|
|
|
negative regulation of cell differentiation
|
GO:0045596 |
171 |
0.064
|
|
|
|
smad protein signal transduction
|
GO:0060395 |
10 |
0.064
|
|
|
|
heart process
|
GO:0003015 |
62 |
0.063
|
|
|
|
positive regulation of transcription from rna polymerase ii promoter in response to hypoxia
|
GO:0061419 |
2 |
0.063
|
|
|
|
regulation of cysteine type endopeptidase activity
|
GO:2000116 |
127 |
0.063
|
|
|
|
response to external biotic stimulus
|
GO:0043207 |
261 |
0.062
|
|
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.062
|
Human |
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.062
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
244 |
0.062
|
|
|
|
ketone biosynthetic process
|
GO:0042181 |
17 |
0.062
|
|
|
|
cardiac muscle contraction
|
GO:0060048 |
34 |
0.062
|
|
|
|
bone development
|
GO:0060348 |
26 |
0.062
|
|
|
|
multi organism cellular process
|
GO:0044764 |
156 |
0.062
|
|
|
|
zymogen activation
|
GO:0031638 |
70 |
0.061
|
|
|
|
ventricular septum development
|
GO:0003281 |
5 |
0.061
|
|
|
|
oxidoreduction coenzyme metabolic process
|
GO:0006733 |
19 |
0.061
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
172 |
0.060
|
|
|
|
negative regulation of cellular response to growth factor stimulus
|
GO:0090288 |
41 |
0.060
|
|
|
|
negative regulation of transcription by competitive promoter binding
|
GO:0010944 |
8 |
0.060
|
|
|
|
regulation of peptidyl serine phosphorylation
|
GO:0033135 |
50 |
0.059
|
|
|
|
regulation of protein ubiquitination
|
GO:0031396 |
95 |
0.059
|
|
|
|
ribonucleoprotein complex export from nucleus
|
GO:0071426 |
4 |
0.059
|
|
|
|
determination of bilateral symmetry
|
GO:0009855 |
15 |
0.059
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
113 |
0.059
|
|
|
|
regulation of endosome size
|
GO:0051036 |
3 |
0.059
|
|
|
|
positive regulation of mesoderm development
|
GO:2000382 |
2 |
0.058
|
|
|
|
mesonephric tubule development
|
GO:0072164 |
14 |
0.058
|
|
|
|
endosomal transport
|
GO:0016197 |
129 |
0.058
|
|
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.058
|
|
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.056
|
|
|
|
establishment of ribosome localization
|
GO:0033753 |
4 |
0.056
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.056
|
|
|
|
peptidyl threonine modification
|
GO:0018210 |
45 |
0.056
|
|
|
|
pituitary gland development
|
GO:0021983 |
2 |
0.055
|
|
|
|
positive regulation of cellular protein catabolic process
|
GO:1903364 |
37 |
0.055
|
|
|
|
alcohol metabolic process
|
GO:0006066 |
114 |
0.055
|
|
|
|
defense response
|
GO:0006952 |
315 |
0.055
|
|
|
|
cell fate commitment
|
GO:0045165 |
27 |
0.055
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.054
|
|
|
|
regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903050 |
91 |
0.054
|
|
|
|
small molecule biosynthetic process
|
GO:0044283 |
157 |
0.054
|
|
|
|
renal vesicle development
|
GO:0072087 |
4 |
0.054
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.053
|
|
|
|
positive regulation of intracellular transport
|
GO:0032388 |
104 |
0.053
|
|
|
|
response to defenses of other organism involved in symbiotic interaction
|
GO:0052173 |
2 |
0.053
|
|
|
|
negative regulation of ion transmembrane transport
|
GO:0034766 |
26 |
0.053
|
|
|
|
steroid metabolic process
|
GO:0008202 |
94 |
0.053
|
|
|
|
ventricular cardiac muscle tissue development
|
GO:0003229 |
14 |
0.053
|
|
|
|
axon cargo transport
|
GO:0008088 |
2 |
0.053
|
|
|
|
gastrulation with mouth forming second
|
GO:0001702 |
1 |
0.052
|
|
|
|
dissemination or transmission of symbiont from host
|
GO:0044007 |
1 |
0.052
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.052
|
|
|
|
cell migration involved in gastrulation
|
GO:0042074 |
1 |
0.052
|
|
|
|
neurogenesis
|
GO:0022008 |
169 |
0.051
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
380 |
0.051
|
|
|
|
isoprenoid metabolic process
|
GO:0006720 |
39 |
0.051
|
|
|
|
regulation of nodal signaling pathway involved in determination of lateral mesoderm left right asymmetry
|
GO:1900175 |
1 |
0.051
|
|
|
|
autophagy
|
GO:0006914 |
88 |
0.051
|
|
|
|
regulation of protein complex assembly
|
GO:0043254 |
147 |
0.051
|
|
|
|
cellular response to lipid
|
GO:0071396 |
127 |
0.050
|
|
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.050
|
|
|
|
negative regulation of ubiquitin protein transferase activity
|
GO:0051444 |
8 |
0.050
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
3 |
0.050
|
|
|
|
lymphocyte activation
|
GO:0046649 |
133 |
0.050
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.050
|
|
|
|
sodium ion transport
|
GO:0006814 |
61 |
0.050
|
|
|
|
lateral mesoderm development
|
GO:0048368 |
1 |
0.050
|
|
|
|
cell adhesion
|
GO:0007155 |
325 |
0.049
|
|
|
|
digestive system development
|
GO:0055123 |
75 |
0.049
|
|
|
|
embryonic placenta development
|
GO:0001892 |
1 |
0.049
|
|
|
|
skeletal system development
|
GO:0001501 |
79 |
0.049
|
|
|
|
regulation of ribosome biogenesis
|
GO:0090069 |
1 |
0.049
|
|
|
|
regulation of bmp signaling pathway
|
GO:0030510 |
27 |
0.048
|
|
|
|
heart contraction
|
GO:0060047 |
62 |
0.048
|
|
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
147 |
0.048
|
|
|
|
organ morphogenesis
|
GO:0009887 |
147 |
0.048
|
|
|
|
receptor metabolic process
|
GO:0043112 |
81 |
0.047
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.047
|
|
|
|
cofactor biosynthetic process
|
GO:0051188 |
31 |
0.047
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
261 |
0.047
|
|
|
|
positive regulation of transforming growth factor beta receptor signaling pathway
|
GO:0030511 |
12 |
0.046
|
|
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
4 |
0.046
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
204 |
0.046
|
|
|
|
circulatory system development
|
GO:0072359 |
262 |
0.046
|
|
|
|
embryo development
|
GO:0009790 |
123 |
0.045
|
|
|
|
nodal signaling pathway
|
GO:0038092 |
5 |
0.045
|
|
|
|
negative regulation of mitotic cell cycle
|
GO:0045930 |
102 |
0.045
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.045
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
213 |
0.045
|
|
|
|
regulation of alkaline phosphatase activity
|
GO:0010692 |
2 |
0.045
|
|
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
324 |
0.045
|
|
|
|
regulation of nervous system development
|
GO:0051960 |
88 |
0.045
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
193 |
0.045
|
|
|
|
fatty acid metabolic process
|
GO:0006631 |
115 |
0.045
|
|
|
|
dissemination or transmission of organism from other organism involved in symbiotic interaction
|
GO:0051821 |
1 |
0.044
|
|
|
|
renal tubule development
|
GO:0061326 |
19 |
0.044
|
|
|
|
response to sterol
|
GO:0036314 |
14 |
0.044
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.044
|
|
|
|
regulation of proteasomal ubiquitin dependent protein catabolic process
|
GO:0032434 |
71 |
0.044
|
|
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.044
|
|
|
|
proteasomal protein catabolic process
|
GO:0010498 |
176 |
0.044
|
|
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043281 |
116 |
0.043
|
|
|
|
cardiac chamber morphogenesis
|
GO:0003206 |
26 |
0.043
|
|
|
|
lens development in camera type eye
|
GO:0002088 |
2 |
0.043
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
191 |
0.042
|
|
|
|
negative regulation of ligase activity
|
GO:0051352 |
8 |
0.042
|
|
|
|
microtubule based process
|
GO:0007017 |
210 |
0.042
|
|
|
|
regulation of cell morphogenesis
|
GO:0022604 |
153 |
0.042
|
|
|
|
morphogenesis of an epithelium
|
GO:0002009 |
60 |
0.041
|
|
|
|
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090100 |
41 |
0.041
|
|
|
|
intracellular steroid hormone receptor signaling pathway
|
GO:0030518 |
61 |
0.041
|
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
176 |
0.041
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
189 |
0.041
|
|
|
|
negative regulation of protein transport
|
GO:0051224 |
75 |
0.040
|
|
|
|
oogenesis
|
GO:0048477 |
2 |
0.040
|
|
|
|
protein export from nucleus
|
GO:0006611 |
29 |
0.040
|
|
|
|
regulation of heart morphogenesis
|
GO:2000826 |
4 |
0.040
|
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
209 |
0.040
|
|
|
|
regulation of proteasomal protein catabolic process
|
GO:0061136 |
87 |
0.040
|
|
|
|
hard palate development
|
GO:0060022 |
1 |
0.040
|
|
|
|
positive regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903052 |
35 |
0.039
|
|
|
|
positive regulation of protein import into nucleus
|
GO:0042307 |
46 |
0.039
|
|
|
|
positive regulation of chondrocyte differentiation
|
GO:0032332 |
4 |
0.039
|
|
|
|
regulation of ion transmembrane transport
|
GO:0034765 |
132 |
0.039
|
|
|
|
regulation of ubiquitin protein transferase activity
|
GO:0051438 |
28 |
0.039
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.039
|
|
|
|
regulation of schwann cell proliferation
|
GO:0010624 |
1 |
0.039
|
|
|
|
regulation of leukocyte activation
|
GO:0002694 |
115 |
0.038
|
|
|
|
nuclear export
|
GO:0051168 |
69 |
0.038
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.038
|
|
|
|
regulation of growth
|
GO:0040008 |
165 |
0.038
|
|
|
|
isoprenoid biosynthetic process
|
GO:0008299 |
9 |
0.038
|
|
|
|
neural tube formation
|
GO:0001841 |
3 |
0.038
|
|
|
|
protein polyubiquitination
|
GO:0000209 |
110 |
0.038
|
|
|
|
epithelial cell differentiation
|
GO:0030855 |
141 |
0.037
|
|
|
|
chromatin organization
|
GO:0006325 |
351 |
0.037
|
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
123 |
0.037
|
|
|
|
inositol lipid mediated signaling
|
GO:0048017 |
55 |
0.037
|
|
|
|
dephosphorylation
|
GO:0016311 |
209 |
0.037
|
|
|
|
ubiquinone metabolic process
|
GO:0006743 |
5 |
0.036
|
|
|
|
cell growth
|
GO:0016049 |
160 |
0.036
|
|
|
|
activation of cysteine type endopeptidase activity
|
GO:0097202 |
57 |
0.036
|
|
|
|
cellular protein complex assembly
|
GO:0043623 |
188 |
0.036
|
|
|
|
regulation of potassium ion transmembrane transporter activity
|
GO:1901016 |
16 |
0.036
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.036
|
|
|
|
vascular smooth muscle cell development
|
GO:0097084 |
1 |
0.035
|
|
|
|
regulation of cell cell adhesion
|
GO:0022407 |
57 |
0.035
|
|
|
|
protein targeting
|
GO:0006605 |
187 |
0.035
|
|
|
|
regulation of coenzyme metabolic process
|
GO:0051196 |
3 |
0.035
|
|
|
|
positive regulation of endopeptidase activity
|
GO:0010950 |
84 |
0.035
|
|
|
|
tissue morphogenesis
|
GO:0048729 |
96 |
0.035
|
|
|
|
nucleobase containing compound transport
|
GO:0015931 |
51 |
0.035
|
|
|
|
lipid transport
|
GO:0006869 |
90 |
0.035
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.035
|
|
|
|
sterol metabolic process
|
GO:0016125 |
28 |
0.035
|
|
|
|
lymphocyte proliferation
|
GO:0046651 |
70 |
0.035
|
|
|
|
positive regulation of phosphatidylinositol 3 kinase signaling
|
GO:0014068 |
28 |
0.034
|
|
|
|
circulatory system process
|
GO:0003013 |
113 |
0.034
|
|
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.034
|
|
|
|
positive regulation of cysteine type endopeptidase activity
|
GO:2001056 |
79 |
0.033
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.033
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.033
|
|
|
|
regionalization
|
GO:0003002 |
29 |
0.033
|
|
|
|
regulation of cellular protein catabolic process
|
GO:1903362 |
96 |
0.033
|
|
|
|
regulation of transforming growth factor beta production
|
GO:0071634 |
13 |
0.033
|
|
|
|
myeloid cell homeostasis
|
GO:0002262 |
34 |
0.033
|
|
|
|
embryonic epithelial tube formation
|
GO:0001838 |
4 |
0.033
|
|
|
|
notch signaling pathway
|
GO:0007219 |
31 |
0.033
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
169 |
0.033
|
|
|
|
head development
|
GO:0060322 |
108 |
0.033
|
|
|
|
fat soluble vitamin metabolic process
|
GO:0006775 |
19 |
0.033
|
|
|
|
endodermal cell differentiation
|
GO:0035987 |
31 |
0.033
|
|
|
|
endochondral bone morphogenesis
|
GO:0060350 |
3 |
0.033
|
|
|
|
positive regulation of transcription factor import into nucleus
|
GO:0042993 |
25 |
0.033
|
|
|
|
reproductive process
|
GO:0022414 |
106 |
0.033
|
|
|
|
inorganic cation transmembrane transport
|
GO:0098662 |
194 |
0.033
|
|
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.032
|
|
|
|
negative regulation of intracellular steroid hormone receptor signaling pathway
|
GO:0033144 |
18 |
0.032
|
|
|
|
regulation of androgen receptor activity
|
GO:2000823 |
3 |
0.032
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.032
|
|
|
|
negative regulation of growth
|
GO:0045926 |
97 |
0.032
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
175 |
0.032
|
|
|
|
mononuclear cell proliferation
|
GO:0032943 |
71 |
0.032
|
|
|
|
negative regulation of transporter activity
|
GO:0032410 |
25 |
0.032
|
|
|
|
cell cycle arrest
|
GO:0007050 |
71 |
0.032
|
|
|
|
positive regulation of jnk cascade
|
GO:0046330 |
52 |
0.031
|
|
|
|
lipid modification
|
GO:0030258 |
84 |
0.031
|
|
|
|
response to cholesterol
|
GO:0070723 |
11 |
0.031
|
|
|
|
regulation of receptor mediated endocytosis
|
GO:0048259 |
32 |
0.031
|
|
|
|
vascular smooth muscle cell differentiation
|
GO:0035886 |
3 |
0.031
|
|
|
|
blastoderm segmentation
|
GO:0007350 |
2 |
0.031
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.030
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.030
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.030
|
|
|
|
regulation of lipid biosynthetic process
|
GO:0046890 |
47 |
0.030
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.030
|
|
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
212 |
0.030
|
|
|
|
protein stabilization
|
GO:0050821 |
64 |
0.030
|
|
|
|
negative regulation of wnt signaling pathway
|
GO:0030178 |
69 |
0.030
|
Human |
|
|
regulation of cellular component size
|
GO:0032535 |
82 |
0.030
|
|
|
|
pathway restricted smad protein phosphorylation
|
GO:0060389 |
38 |
0.030
|
|
|
|
positive regulation of ossification
|
GO:0045778 |
32 |
0.029
|
|
|
|
regulation of cardiac muscle contraction
|
GO:0055117 |
33 |
0.029
|
|
|
|
phosphatidylinositol mediated signaling
|
GO:0048015 |
55 |
0.029
|
|
|
|
histone modification
|
GO:0016570 |
251 |
0.029
|
|
|
|
activation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0006919 |
49 |
0.029
|
|
|
|
mesonephros development
|
GO:0001823 |
17 |
0.029
|
|
|
|
angiogenesis
|
GO:0001525 |
147 |
0.028
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
232 |
0.028
|
|
|
|
negative regulation of cell cycle process
|
GO:0010948 |
121 |
0.028
|
|
|
|
negative regulation of ion transport
|
GO:0043271 |
39 |
0.028
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.028
|
|
|
|
quinone metabolic process
|
GO:1901661 |
18 |
0.028
|
|
|
|
regulation of system process
|
GO:0044057 |
101 |
0.028
|
|
|
|
embryonic eye morphogenesis
|
GO:0048048 |
2 |
0.028
|
|
|
|
regulation of ligase activity
|
GO:0051340 |
29 |
0.028
|
|
|
|
regulation of cell activation
|
GO:0050865 |
125 |
0.028
|
|
|
|
regulation of heart contraction
|
GO:0008016 |
50 |
0.028
|
|
|
|
response to uv
|
GO:0009411 |
73 |
0.028
|
|
|
|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
156 |
0.028
|
|
|
|
fat cell differentiation
|
GO:0045444 |
32 |
0.028
|
|
|
|
positive regulation of nucleocytoplasmic transport
|
GO:0046824 |
54 |
0.028
|
|
|
|
positive regulation of catenin import into nucleus
|
GO:0035413 |
9 |
0.027
|
|
|
|
response to oxygen levels
|
GO:0070482 |
100 |
0.027
|
|
|
|
regulation of sodium ion transmembrane transporter activity
|
GO:2000649 |
17 |
0.027
|
|
|
|
regulation of nodal signaling pathway
|
GO:1900107 |
1 |
0.027
|
|
|
|
convergent extension involved in gastrulation
|
GO:0060027 |
1 |
0.027
|
|
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.027
|
|
|
|
glycerolipid metabolic process
|
GO:0046486 |
107 |
0.027
|
|
|
|
cytokine production
|
GO:0001816 |
247 |
0.027
|
|
|
|
pericardium development
|
GO:0060039 |
2 |
0.027
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.027
|
|
|
|
nephron tubule development
|
GO:0072080 |
17 |
0.027
|
|
|
|
trna metabolic process
|
GO:0006399 |
35 |
0.027
|
|
|
|
phosphatidylinositol 3 kinase signaling
|
GO:0014065 |
48 |
0.027
|
|
|
|
regulation of alcohol biosynthetic process
|
GO:1902930 |
22 |
0.027
|
|
|
|
regulation of blood circulation
|
GO:1903522 |
59 |
0.027
|
|
|
|
cell cycle g1 s phase transition
|
GO:0044843 |
80 |
0.027
|
|
|
|
motor neuron axon guidance
|
GO:0008045 |
2 |
0.026
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.026
|
|
|
|
regulation of sodium ion transmembrane transport
|
GO:1902305 |
23 |
0.026
|
|
|
|
spinal cord development
|
GO:0021510 |
4 |
0.026
|
|
|
|
muscle system process
|
GO:0003012 |
81 |
0.026
|
|
|
|
positive regulation of fatty acid biosynthetic process
|
GO:0045723 |
5 |
0.026
|
|
|
|
establishment of endothelial barrier
|
GO:0061028 |
16 |
0.026
|
|
|
|
proximal tubule development
|
GO:0072014 |
1 |
0.026
|
|
