|
|
protein modification by small protein conjugation
|
GO:0032446 |
342 |
1.000
|
|
|
|
negative regulation of transcription from rna polymerase ii promoter
|
GO:0000122 |
281 |
1.000
|
Rat |
|
|
histone modification
|
GO:0016570 |
251 |
1.000
|
Rat |
|
|
chromatin modification
|
GO:0016568 |
298 |
0.999
|
|
|
|
chromatin organization
|
GO:0006325 |
351 |
0.998
|
|
|
|
protein ubiquitination
|
GO:0016567 |
314 |
0.998
|
|
|
|
pml body organization
|
GO:0030578 |
2 |
0.997
|
Rat |
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.995
|
Mouse |
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
175 |
0.991
|
Mouse |
|
|
chromatin assembly
|
GO:0031497 |
61 |
0.990
|
|
|
|
covalent chromatin modification
|
GO:0016569 |
254 |
0.990
|
Rat |
|
|
response to decreased oxygen levels
|
GO:0036293 |
96 |
0.983
|
Rat |
|
|
chromatin assembly or disassembly
|
GO:0006333 |
78 |
0.973
|
|
|
|
macromolecule methylation
|
GO:0043414 |
97 |
0.973
|
|
|
|
histone methylation
|
GO:0016571 |
60 |
0.973
|
|
|
|
nucleosome assembly
|
GO:0006334 |
50 |
0.971
|
|
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
70 |
0.965
|
Mouse |
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.962
|
|
|
|
pituitary gland development
|
GO:0021983 |
2 |
0.957
|
|
|
|
regulation of protein ubiquitination
|
GO:0031396 |
95 |
0.957
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.955
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.954
|
Rat |
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.953
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.951
|
|
|
|
negative regulation of protein ubiquitination involved in ubiquitin dependent protein catabolic process
|
GO:2000059 |
3 |
0.950
|
|
|
|
positive regulation of protein modification by small protein conjugation or removal
|
GO:1903322 |
61 |
0.938
|
|
|
|
protein sumoylation
|
GO:0016925 |
25 |
0.937
|
|
|
|
dna replication dependent nucleosome organization
|
GO:0034723 |
32 |
0.935
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.932
|
|
|
|
positive regulation of apoptotic process involved in morphogenesis
|
GO:1902339 |
1 |
0.932
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.918
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
211 |
0.915
|
|
|
|
cellular response to oxidative stress
|
GO:0034599 |
85 |
0.909
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.907
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.907
|
|
|
|
histone lysine methylation
|
GO:0034968 |
50 |
0.904
|
|
|
|
dna conformation change
|
GO:0071103 |
113 |
0.902
|
|
|
|
response to hypoxia
|
GO:0001666 |
96 |
0.901
|
|
|
|
regulation of protein modification by small protein conjugation or removal
|
GO:1903320 |
107 |
0.897
|
|
|
|
immune system development
|
GO:0002520 |
195 |
0.894
|
|
|
|
negative regulation of viral release from host cell
|
GO:1902187 |
12 |
0.892
|
|
|
|
negative regulation of cell fate commitment
|
GO:0010454 |
3 |
0.885
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.883
|
|
|
|
regulation of endopeptidase activity
|
GO:0052548 |
170 |
0.873
|
|
|
|
gland development
|
GO:0048732 |
48 |
0.870
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.868
|
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
127 |
0.865
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
380 |
0.862
|
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
97 |
0.840
|
|
|
|
cardioblast cell fate commitment
|
GO:0042684 |
1 |
0.832
|
|
|
|
protein acylation
|
GO:0043543 |
138 |
0.832
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
180 |
0.830
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.824
|
|
|
|
dna repair
|
GO:0006281 |
198 |
0.808
|
|
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043281 |
116 |
0.807
|
|
|
|
central nervous system development
|
GO:0007417 |
123 |
0.806
|
|
|
|
negative regulation of sequence specific dna binding transcription factor activity
|
GO:0043433 |
89 |
0.805
|
|
|
|
negative regulation of cell fate specification
|
GO:0009996 |
3 |
0.804
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.792
|
|
|
|
protein acetylation
|
GO:0006473 |
116 |
0.785
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.784
|
Mouse Rat |
|
|
histone acetylation
|
GO:0016573 |
93 |
0.778
|
|
|
|
positive regulation of apoptotic process involved in mammary gland involution
|
GO:0060058 |
1 |
0.777
|
|
|
|
carbohydrate homeostasis
|
GO:0033500 |
31 |
0.773
|
|
|
|
regulation of cell fate commitment
|
GO:0010453 |
7 |
0.768
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.764
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.756
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
261 |
0.755
|
|
|
|
regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903050 |
91 |
0.748
|
|
|
|
regulation of intrinsic apoptotic signaling pathway
|
GO:2001242 |
72 |
0.748
|
|
|
|
protein methylation
|
GO:0006479 |
74 |
0.745
|
|
|
|
protein oligomerization
|
GO:0051259 |
173 |
0.742
|
|
|
|
histone h4 acetylation
|
GO:0043967 |
47 |
0.740
|
|
|
|
activation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0006919 |
49 |
0.738
|
|
|
|
protein deubiquitination
|
GO:0016579 |
79 |
0.730
|
|
|
|
angiogenesis involved in wound healing
|
GO:0060055 |
4 |
0.726
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
193 |
0.718
|
|
|
|
protein processing
|
GO:0016485 |
226 |
0.713
|
|
|
|
regulation of cell growth
|
GO:0001558 |
135 |
0.710
|
|
|
|
regulation of innate immune response
|
GO:0045088 |
97 |
0.709
|
|
|
|
cellular response to hypoxia
|
GO:0071456 |
51 |
0.705
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.700
|
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
155 |
0.685
|
|
|
|
protein polyubiquitination
|
GO:0000209 |
110 |
0.682
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
213 |
0.681
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.672
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
117 |
0.668
|
|
|
|
response to hydrogen peroxide
|
GO:0042542 |
40 |
0.665
|
|
|
|
regulation of cysteine type endopeptidase activity
|
GO:2000116 |
127 |
0.662
|
|
|
|
nuclear body organization
|
GO:0030575 |
4 |
0.661
|
Rat |
|
|
cellular response to oxygen levels
|
GO:0071453 |
55 |
0.655
|
Rat |
|
|
regulation of protein stability
|
GO:0031647 |
87 |
0.655
|
|
|
|
hemopoiesis
|
GO:0030097 |
180 |
0.652
|
|
|
|
peptidyl lysine modification
|
GO:0018205 |
144 |
0.647
|
|
|
|
cellular homeostasis
|
GO:0019725 |
196 |
0.645
|
|
|
|
positive regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043280 |
69 |
0.636
|
|
|
|
vasculature development
|
GO:0001944 |
181 |
0.632
|
|
|
|
regulation of cardiac cell fate specification
|
GO:2000043 |
1 |
0.625
|
|
|
|
glucose homeostasis
|
GO:0042593 |
31 |
0.621
|
|
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.620
|
|
|
|
regulation of cell cycle arrest
|
GO:0071156 |
36 |
0.613
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.608
|
Rat |
|
|
positive regulation of erythrocyte differentiation
|
GO:0045648 |
11 |
0.604
|
|
|
|
embryo development
|
GO:0009790 |
123 |
0.603
|
|
|
|
cellular response to nitrogen compound
|
GO:1901699 |
144 |
0.596
|
|
|
|
regulation of cell development
|
GO:0060284 |
161 |
0.596
|
|
|
|
cellular response to hydrogen peroxide
|
GO:0070301 |
37 |
0.591
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
244 |
0.588
|
|
|
|
response to oxygen levels
|
GO:0070482 |
100 |
0.587
|
Rat |
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
84 |
0.587
|
|
|
|
regulation of viral release from host cell
|
GO:1902186 |
20 |
0.586
|
|
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.586
|
|
|
|
response to hormone
|
GO:0009725 |
175 |
0.576
|
|
|
|
zymogen activation
|
GO:0031638 |
70 |
0.575
|
|
|
|
mitotic cell cycle phase transition
|
GO:0044772 |
162 |
0.573
|
|
|
|
response to toxic substance
|
GO:0009636 |
37 |
0.572
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.570
|
|
|
|
positive regulation of protein sumoylation
|
GO:0033235 |
7 |
0.559
|
|
|
|
epithelial cell differentiation
|
GO:0030855 |
141 |
0.553
|
|
|
|
negative regulation of protein modification by small protein conjugation or removal
|
GO:1903321 |
41 |
0.550
|
|
|
|
regulation of response to dna damage stimulus
|
GO:2001020 |
94 |
0.549
|
|
|
|
cell aging
|
GO:0007569 |
52 |
0.546
|
|
|
|
negative regulation of protein maturation
|
GO:1903318 |
142 |
0.538
|
|
|
|
regulation of cell cycle phase transition
|
GO:1901987 |
126 |
0.538
|
|
|
|
regulation of cardioblast differentiation
|
GO:0051890 |
4 |
0.537
|
|
|
|
protein alkylation
|
GO:0008213 |
74 |
0.534
|
|
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
212 |
0.533
|
|
|
|
negative regulation of protein ubiquitination
|
GO:0031397 |
35 |
0.517
|
|
|
|
regulation of protein processing
|
GO:0070613 |
150 |
0.515
|
|
|
|
intrinsic apoptotic signaling pathway in response to oxidative stress
|
GO:0008631 |
21 |
0.515
|
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
142 |
0.511
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.501
|
|
|
|
positive regulation of i kappab kinase nf kappab signaling
|
GO:0043123 |
132 |
0.500
|
|
|
|
organ morphogenesis
|
GO:0009887 |
147 |
0.499
|
|
|
|
mapk cascade
|
GO:0000165 |
288 |
0.496
|
|
|
|
regulation of protein sumoylation
|
GO:0033233 |
13 |
0.496
|
|
|
|
regulation of metanephros size
|
GO:0035566 |
1 |
0.490
|
|
|
|
dna replication independent nucleosome assembly
|
GO:0006336 |
27 |
0.488
|
|
|
|
methylation
|
GO:0032259 |
106 |
0.487
|
|
|
|
proteasomal protein catabolic process
|
GO:0010498 |
176 |
0.480
|
|
|
|
response to reactive oxygen species
|
GO:0000302 |
61 |
0.479
|
|
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.469
|
|
|
|
androgen receptor signaling pathway
|
GO:0030521 |
34 |
0.465
|
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
206 |
0.456
|
|
|
|
brain development
|
GO:0007420 |
97 |
0.447
|
|
|
|
cellular response to reactive oxygen species
|
GO:0034614 |
50 |
0.445
|
|
|
|
protein export from nucleus
|
GO:0006611 |
29 |
0.442
|
|
|
|
response to cytokine
|
GO:0034097 |
232 |
0.440
|
Rat |
|
|
aging
|
GO:0007568 |
66 |
0.433
|
|
|
|
regulation of myeloid cell differentiation
|
GO:0045637 |
81 |
0.428
|
|
|
|
cardioblast cell fate specification
|
GO:0042685 |
1 |
0.426
|
|
|
|
regulation of protein ubiquitination involved in ubiquitin dependent protein catabolic process
|
GO:2000058 |
7 |
0.426
|
|
|
|
dna packaging
|
GO:0006323 |
77 |
0.425
|
|
|
|
negative regulation of cell growth
|
GO:0030308 |
83 |
0.424
|
|
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.422
|
|
|
|
regulation of cell fate specification
|
GO:0042659 |
5 |
0.421
|
|
|
|
regulation of angiogenesis
|
GO:0045765 |
92 |
0.418
|
|
|
|
cell cycle checkpoint
|
GO:0000075 |
117 |
0.417
|
|
|
|
endocrine system development
|
GO:0035270 |
26 |
0.417
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
195 |
0.416
|
|
|
|
regulation of cellular protein catabolic process
|
GO:1903362 |
96 |
0.416
|
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
176 |
0.416
|
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.412
|
|
|
|
response to growth factor
|
GO:0070848 |
205 |
0.411
|
|
|
|
head development
|
GO:0060322 |
108 |
0.402
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
0.392
|
|
|
|
protein destabilization
|
GO:0031648 |
12 |
0.392
|
|
|
|
regulation of dna metabolic process
|
GO:0051052 |
153 |
0.391
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
136 |
0.389
|
|
|
|
positive regulation of cysteine type endopeptidase activity
|
GO:2001056 |
79 |
0.387
|
|
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
131 |
0.385
|
|
|
|
regulation of proteasomal ubiquitin dependent protein catabolic process
|
GO:0032434 |
71 |
0.383
|
|
|
|
nuclear transport
|
GO:0051169 |
179 |
0.383
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
125 |
0.382
|
|
|
|
protein dna complex assembly
|
GO:0065004 |
64 |
0.378
|
|
|
|
cation transport
|
GO:0006812 |
331 |
0.376
|
|
|
|
locomotory behavior
|
GO:0007626 |
1 |
0.373
|
|
|
|
regulation of i kappab kinase nf kappab signaling
|
GO:0043122 |
162 |
0.372
|
|
|
|
response to nitrogen compound
|
GO:1901698 |
184 |
0.360
|
|
|
|
urate metabolic process
|
GO:0046415 |
11 |
0.360
|
|
|
|
positive regulation of endopeptidase activity
|
GO:0010950 |
84 |
0.356
|
|
|
|
dna replication dependent nucleosome assembly
|
GO:0006335 |
32 |
0.347
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
162 |
0.345
|
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
166 |
0.344
|
|
|
|
cell fate specification
|
GO:0001708 |
8 |
0.340
|
|
|
|
response to oxidative stress
|
GO:0006979 |
121 |
0.338
|
|
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.335
|
|
|
|
ribonucleoside monophosphate metabolic process
|
GO:0009161 |
187 |
0.333
|
|
|
|
dna damage response signal transduction resulting in transcription
|
GO:0042772 |
12 |
0.330
|
|
|
|
negative regulation of cell cycle process
|
GO:0010948 |
121 |
0.329
|
|
|
|
chemical homeostasis
|
GO:0048878 |
306 |
0.328
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.325
|
|
|
|
protein maturation
|
GO:0051604 |
233 |
0.323
|
|
|
|
dna damage response signal transduction by p53 class mediator
|
GO:0030330 |
44 |
0.320
|
|
|
|
circulatory system development
|
GO:0072359 |
262 |
0.318
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.308
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.305
|
|
|
|
negative regulation of protein deubiquitination
|
GO:0090086 |
3 |
0.302
|
|
|
|
morphogenesis of a branching structure
|
GO:0001763 |
21 |
0.299
|
|
|
|
cell growth
|
GO:0016049 |
160 |
0.293
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.291
|
Rat |
|
|
response to alcohol
|
GO:0097305 |
64 |
0.288
|
|
|
|
negative regulation of protein catabolic process
|
GO:0042177 |
59 |
0.285
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.285
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
135 |
0.285
|
|
|
|
regulation of extrinsic apoptotic signaling pathway in absence of ligand
|
GO:2001239 |
20 |
0.280
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
124 |
0.279
|
|
|
|
positive regulation of myeloid cell differentiation
|
GO:0045639 |
39 |
0.276
|
|
|
|
mitotic g1 dna damage checkpoint
|
GO:0031571 |
17 |
0.273
|
|
|
|
erythrocyte differentiation
|
GO:0030218 |
28 |
0.271
|
|
|
|
response to inorganic substance
|
GO:0010035 |
127 |
0.270
|
Rat |
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
119 |
0.269
|
|
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.268
|
|
|
|
negative regulation of mitotic cell cycle
|
GO:0045930 |
102 |
0.265
|
|
|
|
negative regulation of cardiac cell fate specification
|
GO:2000044 |
1 |
0.262
|
|
|
|
negative regulation of protein processing
|
GO:0010955 |
142 |
0.262
|
|
|
|
apoptotic mitochondrial changes
|
GO:0008637 |
57 |
0.258
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.258
|
|
|
|
chordate embryonic development
|
GO:0043009 |
34 |
0.255
|
|
|
|
cellular senescence
|
GO:0090398 |
34 |
0.253
|
|
|
|
histone ubiquitination
|
GO:0016574 |
31 |
0.252
|
|
|
|
peptidyl lysine acetylation
|
GO:0018394 |
101 |
0.249
|
|
|
|
protein dna complex subunit organization
|
GO:0071824 |
80 |
0.248
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.247
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.245
|
|
|
|
gene silencing
|
GO:0016458 |
49 |
0.244
|
|
|
|
ion homeostasis
|
GO:0050801 |
230 |
0.242
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.241
|
|
|
|
negative regulation of proteolysis
|
GO:0045861 |
132 |
0.239
|
|
|
|
anterior posterior axis specification
|
GO:0009948 |
2 |
0.239
|
|
|
|
blood vessel development
|
GO:0001568 |
172 |
0.236
|
|
|
|
epithelium migration
|
GO:0090132 |
119 |
0.235
|
|
|
|
cellular response to hyperoxia
|
GO:0071455 |
4 |
0.232
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.230
|
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
209 |
0.230
|
|
|
|
purine nucleoside monophosphate metabolic process
|
GO:0009126 |
186 |
0.229
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
140 |
0.227
|
|
|
|
chromatin remodeling
|
GO:0006338 |
55 |
0.227
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.226
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
98 |
0.226
|
|
|
|
double strand break repair
|
GO:0006302 |
101 |
0.219
|
|
|
|
retina layer formation
|
GO:0010842 |
3 |
0.218
|
|
|
|
regulation of protein maturation
|
GO:1903317 |
150 |
0.218
|
|
|
|
viral release from host cell
|
GO:0019076 |
21 |
0.217
|
|
|
|
negative regulation of endopeptidase activity
|
GO:0010951 |
84 |
0.214
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.214
|
Mouse |
|
|
epithelial cell migration
|
GO:0010631 |
119 |
0.214
|
|
|
|
response to lipid
|
GO:0033993 |
206 |
0.213
|
|
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.211
|
|
|
|
embryonic organ development
|
GO:0048568 |
36 |
0.210
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
156 |
0.210
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.210
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.210
|
Mouse Rat |
|
|
signal transduction in response to dna damage
|
GO:0042770 |
57 |
0.208
|
|
|
|
negative regulation of chromosome organization
|
GO:2001251 |
48 |
0.202
|
|
|
|
protein targeting
|
GO:0006605 |
187 |
0.202
|
|
|
|
regulation of neuron death
|
GO:1901214 |
56 |
0.200
|
|
|
|
pharynx development
|
GO:0060465 |
1 |
0.200
|
|
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.198
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
204 |
0.198
|
|
|
|
mitotic dna damage checkpoint
|
GO:0044773 |
28 |
0.197
|
|
|
|
regulation of ion homeostasis
|
GO:2000021 |
73 |
0.196
|
|
|
|
intracellular steroid hormone receptor signaling pathway
|
GO:0030518 |
61 |
0.195
|
|
|
|
dna replication
|
GO:0006260 |
116 |
0.195
|
|
|
|
protein stabilization
|
GO:0050821 |
64 |
0.192
|
|
|
|
microtubule based process
|
GO:0007017 |
210 |
0.192
|
|
|
|
activation of cysteine type endopeptidase activity
|
GO:0097202 |
57 |
0.191
|
|
|
|
translation
|
GO:0006412 |
132 |
0.191
|
|
|
|
neuroblast proliferation
|
GO:0007405 |
4 |
0.191
|
|
|
|
signal transduction by p53 class mediator
|
GO:0072331 |
72 |
0.190
|
|
|
|
protein modification by small protein removal
|
GO:0070646 |
92 |
0.190
|
|
|
|
regulation of thyroid hormone generation
|
GO:2000609 |
2 |
0.189
|
|
|
|
cell cycle arrest
|
GO:0007050 |
71 |
0.188
|
|
|
|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
156 |
0.187
|
|
|
|
chromatin silencing
|
GO:0006342 |
12 |
0.186
|
|
|
|
cell fate commitment
|
GO:0045165 |
27 |
0.185
|
|
|
|
interspecies interaction between organisms
|
GO:0044419 |
156 |
0.185
|
|
|
|
intracellular receptor signaling pathway
|
GO:0030522 |
104 |
0.184
|
|
|
|
negative regulation of intrinsic apoptotic signaling pathway
|
GO:2001243 |
40 |
0.183
|
|
|
|
tripartite regional subdivision
|
GO:0007351 |
2 |
0.183
|
|
|
|
positive regulation of intrinsic apoptotic signaling pathway
|
GO:2001244 |
28 |
0.182
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
181 |
0.182
|
Rat |
|
|
defense response
|
GO:0006952 |
315 |
0.181
|
|
|
|
maintenance of location
|
GO:0051235 |
112 |
0.179
|
|
|
|
digestive system development
|
GO:0055123 |
75 |
0.179
|
|
|
|
chromosome segregation
|
GO:0007059 |
114 |
0.178
|
|
|
|
meiotic chromosome segregation
|
GO:0045132 |
4 |
0.176
|
|
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
85 |
0.176
|
|
|
|
regulation of vasculature development
|
GO:1901342 |
97 |
0.175
|
|
|
|
protein k63 linked ubiquitination
|
GO:0070534 |
31 |
0.174
|
|
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
41 |
0.172
|
|
|
|
regulation of mitotic cell cycle phase transition
|
GO:1901990 |
118 |
0.168
|
|
|
|
forebrain generation of neurons
|
GO:0021872 |
3 |
0.167
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.167
|
|
|
|
regulation of nucleocytoplasmic transport
|
GO:0046822 |
98 |
0.165
|
|
|
|
negative regulation of nf kappab transcription factor activity
|
GO:0032088 |
51 |
0.161
|
|
|
|
regulation of ion transport
|
GO:0043269 |
189 |
0.161
|
|
|
|
organelle fission
|
GO:0048285 |
149 |
0.161
|
|
|
|
regulation of erythrocyte differentiation
|
GO:0045646 |
17 |
0.160
|
|
|
|
mitotic cell cycle checkpoint
|
GO:0007093 |
68 |
0.160
|
|
|
|
protein ubiquitination involved in ubiquitin dependent protein catabolic process
|
GO:0042787 |
37 |
0.160
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
189 |
0.159
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.158
|
|
|
|
negative regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043154 |
46 |
0.157
|
|
|
|
embryonic morphogenesis
|
GO:0048598 |
85 |
0.157
|
|
|
|
skeletal system development
|
GO:0001501 |
79 |
0.156
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.155
|
|
|
|
regeneration
|
GO:0031099 |
4 |
0.155
|
|
|
|
anatomical structure homeostasis
|
GO:0060249 |
100 |
0.154
|
|
|
|
positive regulation of wnt signaling pathway
|
GO:0030177 |
54 |
0.154
|
|
|
|
histone h3 k4 methylation
|
GO:0051568 |
27 |
0.150
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.150
|
|
|
|
positive regulation of cellular protein catabolic process
|
GO:1903364 |
37 |
0.149
|
|
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
109 |
0.149
|
|
|
|
positive regulation of protein complex assembly
|
GO:0031334 |
86 |
0.148
|
|
|
|
negative regulation of cardioblast cell fate specification
|
GO:0009997 |
1 |
0.148
|
|
|
|
negative regulation of gene expression epigenetic
|
GO:0045814 |
19 |
0.146
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.145
|
|
|
|
negative regulation of organelle organization
|
GO:0010639 |
126 |
0.144
|
|
|
|
hypothalamus development
|
GO:0021854 |
1 |
0.142
|
|
|
|
regulation of intracellular steroid hormone receptor signaling pathway
|
GO:0033143 |
32 |
0.142
|
|
|
|
negative regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903051 |
35 |
0.141
|
|
|
|
cellular modified amino acid metabolic process
|
GO:0006575 |
64 |
0.141
|
|
|
|
hormone metabolic process
|
GO:0042445 |
61 |
0.140
|
|
|
|
defense response to other organism
|
GO:0098542 |
129 |
0.140
|
|
|
|
regulation of response to external stimulus
|
GO:0032101 |
222 |
0.140
|
|
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.139
|
|
|
|
regulation of jnk cascade
|
GO:0046328 |
73 |
0.138
|
|
|
|
hematopoietic progenitor cell differentiation
|
GO:0002244 |
38 |
0.138
|
|
|
|
embryonic epithelial tube formation
|
GO:0001838 |
4 |
0.137
|
|
|
|
negative regulation of cell differentiation
|
GO:0045596 |
171 |
0.137
|
Rat |
|
|
negative regulation of growth
|
GO:0045926 |
97 |
0.137
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.136
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.135
|
|
|
|
negative regulation of cell cycle phase transition
|
GO:1901988 |
89 |
0.135
|
|
|
|
regulation of response to biotic stimulus
|
GO:0002831 |
55 |
0.134
|
|
|
|
sensory organ development
|
GO:0007423 |
52 |
0.131
|
|
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.131
|
|
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.131
|
|
|
|
signal transduction involved in dna damage checkpoint
|
GO:0072422 |
15 |
0.130
|
|
|
|
interaction with host
|
GO:0051701 |
42 |
0.130
|
|
|
|
regulation of chromosome organization
|
GO:0033044 |
103 |
0.130
|
Rat |
|
|
negative regulation of cellular catabolic process
|
GO:0031330 |
83 |
0.130
|
|
|
|
digestive tract morphogenesis
|
GO:0048546 |
56 |
0.128
|
|
|
|
negative regulation of multi organism process
|
GO:0043901 |
92 |
0.126
|
|
|
|
regulation of interleukin 2 secretion
|
GO:1900040 |
2 |
0.124
|
|
|
|
interleukin 2 secretion
|
GO:0070970 |
3 |
0.122
|
|
|
|
cellular cation homeostasis
|
GO:0030003 |
163 |
0.121
|
|
|
|
lens development in camera type eye
|
GO:0002088 |
2 |
0.120
|
|
|
|
response to ionizing radiation
|
GO:0010212 |
65 |
0.119
|
|
|
|
metal ion transport
|
GO:0030001 |
272 |
0.119
|
|
|
|
positive regulation of mammary gland involution
|
GO:1903521 |
1 |
0.118
|
|
|
|
protein import into nucleus
|
GO:0006606 |
104 |
0.117
|
|
|
|
positive regulation of viral entry into host cell
|
GO:0046598 |
3 |
0.116
|
|
|
|
positive regulation of protein catabolic process
|
GO:0045732 |
75 |
0.114
|
|
|
|
forebrain development
|
GO:0030900 |
26 |
0.113
|
|
|
|
mitotic dna integrity checkpoint
|
GO:0044774 |
30 |
0.112
|
|
|
|
regulation of stress activated protein kinase signaling cascade
|
GO:0070302 |
85 |
0.111
|
|
|
|
nucleus organization
|
GO:0006997 |
28 |
0.109
|
Rat |
|
|
internal protein amino acid acetylation
|
GO:0006475 |
101 |
0.108
|
|
|
|
cellular response to abiotic stimulus
|
GO:0071214 |
117 |
0.108
|
|
|
|
regulation of cytokine mediated signaling pathway
|
GO:0001959 |
41 |
0.107
|
|
|
|
negative regulation of protein transport
|
GO:0051224 |
75 |
0.107
|
|
|
|
positive regulation of cell cycle process
|
GO:0090068 |
106 |
0.106
|
|
|
|
programmed necrotic cell death
|
GO:0097300 |
18 |
0.105
|
|
|
|
response to endoplasmic reticulum stress
|
GO:0034976 |
49 |
0.105
|
|
|
|
protein k48 linked ubiquitination
|
GO:0070936 |
38 |
0.105
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.104
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
392 |
0.104
|
|
|
|
regulation of epithelial cell migration
|
GO:0010632 |
93 |
0.104
|
|
|
|
mammary gland morphogenesis
|
GO:0060443 |
2 |
0.104
|
|
|
|
tissue migration
|
GO:0090130 |
119 |
0.103
|
|
|
|
trachea development
|
GO:0060438 |
1 |
0.103
|
|
|
|
response to estradiol
|
GO:0032355 |
23 |
0.103
|
|
|
|
negative regulation of catabolic process
|
GO:0009895 |
104 |
0.102
|
|
|
|
positive regulation of nf kappab transcription factor activity
|
GO:0051092 |
81 |
0.102
|
|
|
|
negative regulation of protein kinase activity
|
GO:0006469 |
98 |
0.100
|
|
|
|
thyroid hormone generation
|
GO:0006590 |
2 |
0.099
|
|
|
|
dna damage response signal transduction by p53 class mediator resulting in transcription of p21 class mediator
|
GO:0006978 |
11 |
0.099
|
|
|
|
t cell selection
|
GO:0045058 |
4 |
0.098
|
|
|
|
negative regulation of mitotic cell cycle phase transition
|
GO:1901991 |
85 |
0.098
|
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.097
|
|
|
|
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
|
GO:0070059 |
12 |
0.097
|
|
|
|
epithelial cell development
|
GO:0002064 |
34 |
0.096
|
|
|
|
common partner smad protein phosphorylation
|
GO:0007182 |
3 |
0.096
|
|
|
|
positive regulation of proteasomal protein catabolic process
|
GO:1901800 |
35 |
0.095
|
|
|
|
multi organism cellular process
|
GO:0044764 |
156 |
0.095
|
|
|
|
intracellular signal transduction involved in g1 dna damage checkpoint
|
GO:1902400 |
10 |
0.095
|
|
|
|
positive regulation of peptidase activity
|
GO:0010952 |
88 |
0.094
|
|
|
|
response to peptide
|
GO:1901652 |
65 |
0.094
|
|
|
|
negative regulation of intracellular protein transport
|
GO:0090317 |
42 |
0.094
|
|
|
|
purine ribonucleoside monophosphate metabolic process
|
GO:0009167 |
186 |
0.093
|
|
|
|
negative regulation of vasculature development
|
GO:1901343 |
43 |
0.093
|
|
|
|
cellular component disassembly
|
GO:0022411 |
92 |
0.093
|
|
|
|
mesenchymal to epithelial transition involved in metanephros morphogenesis
|
GO:0003337 |
4 |
0.093
|
|
|
|
histone deacetylation
|
GO:0016575 |
32 |
0.092
|
|
|
|
regulation of double strand break repair
|
GO:2000779 |
22 |
0.092
|
|
|
|
regulation of cellular component size
|
GO:0032535 |
82 |
0.092
|
|
|
|
response to antibiotic
|
GO:0046677 |
15 |
0.091
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.091
|
|
|
|
response to increased oxygen levels
|
GO:0036296 |
4 |
0.091
|
|
|
|
positive regulation of cell cycle arrest
|
GO:0071158 |
23 |
0.091
|
|
|
|
t cell activation
|
GO:0042110 |
99 |
0.091
|
|
|
|
regulation of apoptotic process involved in morphogenesis
|
GO:1902337 |
1 |
0.090
|
|
|
|
oogenesis
|
GO:0048477 |
2 |
0.090
|
|
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.090
|
|
|
|
positive regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903052 |
35 |
0.089
|
|
|
|
pattern specification process
|
GO:0007389 |
43 |
0.089
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.089
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
180 |
0.088
|
|
|
|
regulation of protein export from nucleus
|
GO:0046825 |
15 |
0.088
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.086
|
|
|
|
regulation of response to oxidative stress
|
GO:1902882 |
26 |
0.086
|
|
|
|
cellular response to lipid
|
GO:0071396 |
127 |
0.086
|
|
|
|
cell adhesion
|
GO:0007155 |
325 |
0.086
|
|
|
|
response to steroid hormone
|
GO:0048545 |
80 |
0.086
|
|
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.085
|
|
|
|
tissue morphogenesis
|
GO:0048729 |
96 |
0.085
|
|
|
|
intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediator
|
GO:0042771 |
23 |
0.085
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.085
|
|
|
|
regulation of nervous system development
|
GO:0051960 |
88 |
0.084
|
|
|
|
response to other organism
|
GO:0051707 |
261 |
0.084
|
|
|
|
symbiosis encompassing mutualism through parasitism
|
GO:0044403 |
156 |
0.084
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.084
|
|
|
|
protein k48 linked deubiquitination
|
GO:0071108 |
19 |
0.084
|
|
|
|
nuclear export
|
GO:0051168 |
69 |
0.083
|
|
|
|
methylation dependent chromatin silencing
|
GO:0006346 |
3 |
0.083
|
|
|
|
hindlimb morphogenesis
|
GO:0035137 |
2 |
0.082
|
|
|
|
positive regulation of neurogenesis
|
GO:0050769 |
49 |
0.082
|
|
|
|
negative regulation of t cell apoptotic process
|
GO:0070233 |
4 |
0.082
|
|
|
|
cellular response to transforming growth factor beta stimulus
|
GO:0071560 |
94 |
0.082
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
408 |
0.081
|
|
|
|
negative regulation of extrinsic apoptotic signaling pathway
|
GO:2001237 |
52 |
0.081
|
|
|
|
signal transduction in absence of ligand
|
GO:0038034 |
22 |
0.081
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
136 |
0.081
|
|
|
|
angiogenesis
|
GO:0001525 |
147 |
0.081
|
|
|
|
intrinsic apoptotic signaling pathway in response to dna damage
|
GO:0008630 |
50 |
0.080
|
|
|
|
extracellular structure organization
|
GO:0043062 |
41 |
0.079
|
|
|
|
purine ribonucleoside monophosphate catabolic process
|
GO:0009169 |
158 |
0.079
|
|
|
|
regulation of viral transcription
|
GO:0046782 |
34 |
0.079
|
|
|
|
regulation of cellular response to growth factor stimulus
|
GO:0090287 |
76 |
0.079
|
|
|
|
muscle structure development
|
GO:0061061 |
98 |
0.078
|
Rat |
|
|
positive regulation of organelle organization
|
GO:0010638 |
195 |
0.077
|
Rat |
|
|
cell cycle phase transition
|
GO:0044770 |
173 |
0.077
|
|
|
|
interleukin 2 production
|
GO:0032623 |
20 |
0.075
|
|
|
|
regulation of proteasomal protein catabolic process
|
GO:0061136 |
87 |
0.075
|
|
|
|
connective tissue development
|
GO:0061448 |
39 |
0.075
|
|
|
|
regulation of chromatin modification
|
GO:1903308 |
51 |
0.075
|
Rat |
|
|
nitrogen compound transport
|
GO:0071705 |
191 |
0.073
|
|
|
|
negative regulation of peptidase activity
|
GO:0010466 |
91 |
0.073
|
|
|
|
extrinsic apoptotic signaling pathway in absence of ligand
|
GO:0097192 |
22 |
0.073
|
|
|
|
positive regulation of protein ubiquitination
|
GO:0031398 |
53 |
0.072
|
|
|
|
regulation of telomere maintenance
|
GO:0032204 |
13 |
0.072
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
209 |
0.072
|
|
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
61 |
0.072
|
|
|
|
branching morphogenesis of an epithelial tube
|
GO:0048754 |
19 |
0.072
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.071
|
|
|
|
regulation of stem cell differentiation
|
GO:2000736 |
56 |
0.071
|
|
|
|
embryonic hemopoiesis
|
GO:0035162 |
4 |
0.071
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.070
|
|
|
|
negative regulation of transferase activity
|
GO:0051348 |
124 |
0.070
|
|
|
|
negative regulation of kinase activity
|
GO:0033673 |
106 |
0.069
|
|
|
|
regulation of protein deubiquitination
|
GO:0090085 |
4 |
0.069
|
|
|
|
t cell differentiation in thymus
|
GO:0033077 |
4 |
0.069
|
|
|
|
nucleoside monophosphate metabolic process
|
GO:0009123 |
191 |
0.068
|
|
|
|
cellular transition metal ion homeostasis
|
GO:0046916 |
21 |
0.068
|
|
|
|
multi organism metabolic process
|
GO:0044033 |
41 |
0.067
|
|
|
|
protein import
|
GO:0017038 |
130 |
0.067
|
|
|
|
regulation of growth
|
GO:0040008 |
165 |
0.067
|
|
|
|
regulation of defense response
|
GO:0031347 |
154 |
0.067
|
|
|
|
cellular ion homeostasis
|
GO:0006873 |
168 |
0.065
|
|
|
|
regulation of response to cytokine stimulus
|
GO:0060759 |
46 |
0.065
|
|
|
|
digestive tract development
|
GO:0048565 |
75 |
0.064
|
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
94 |
0.064
|
|
|
|
cell death in response to oxidative stress
|
GO:0036473 |
29 |
0.064
|
|
|
|
t cell differentiation
|
GO:0030217 |
29 |
0.063
|
|
|
|
toll signaling pathway
|
GO:0008063 |
2 |
0.063
|
|
|
|
regulation of transcription involved in g2 m transition of mitotic cell cycle
|
GO:0000117 |
1 |
0.063
|
|
|
|
histone h4 k8 acetylation
|
GO:0043982 |
15 |
0.063
|
|
|
|
segmentation
|
GO:0035282 |
4 |
0.062
|
|
|
|
regulation of defense response to virus
|
GO:0050688 |
33 |
0.062
|
|
|
|
transforming growth factor beta receptor signaling pathway
|
GO:0007179 |
76 |
0.062
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.062
|
|
|
|
neuron death
|
GO:0070997 |
65 |
0.061
|
|
|
|
positive regulation of dna metabolic process
|
GO:0051054 |
73 |
0.061
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.061
|
|
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
127 |
0.061
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
125 |
0.061
|
|
