Homo sapiens

166 known processes

EIF2AK2

eukaryotic translation initiation factor 2-alpha kinase 2

(Aliases: EIF2AK1,PKR,MGC126524,PRKR)

EIF2AK2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
gene silencing by mirna GO:0035195 23 1.000
production of mirnas involved in gene silencing by mirna GO:0035196 12 1.000
response to dsrna GO:0043331 25 0.999
dsrna fragmentation GO:0031050 13 0.999
defense response to virus GO:0051607 71 0.998
viral life cycle GO:0019058 132 0.996
cellular response to dsrna GO:0071359 19 0.994
targeting of mrna for destruction involved in rna interference GO:0030423 3 0.994
posttranscriptional gene silencing by rna GO:0035194 25 0.993
production of small rna involved in gene silencing by rna GO:0070918 13 0.992
ribonucleoprotein complex assembly GO:0022618 78 0.991
production of sirna involved in rna interference GO:0030422 3 0.991
posttranscriptional gene silencing GO:0016441 25 0.991
response to other organism GO:0051707 261 0.985
regulation of defense response to virus by host GO:0050691 22 0.984
ncrna metabolic process GO:0034660 108 0.983
negative regulation of defense response to virus GO:0050687 10 0.983
regulation of defense response to virus GO:0050688 33 0.980
gene silencing by rna GO:0031047 26 0.977
positive regulation of interferon beta production GO:0032728 17 0.975
viral process GO:0016032 146 0.966
regulation of multi organism process GO:0043900 157 0.966
rna interference GO:0016246 4 0.964
multi organism cellular process GO:0044764 156 0.960
regulation of viral process GO:0050792 103 0.958
ribonucleoprotein complex biogenesis GO:0022613 116 0.957
response to biotic stimulus GO:0009607 276 0.955
response to virus GO:0009615 126 0.953
interspecies interaction between organisms GO:0044419 156 0.950
nucleic acid phosphodiester bond hydrolysis GO:0090305 102 0.948
cellular macromolecular complex assembly GO:0034622 324 0.931
Mouse
negative regulation of viral process GO:0048525 66 0.927
positive regulation of interferon alpha production GO:0032727 11 0.921
ncrna processing GO:0034470 83 0.919
pre mirna processing GO:0031054 8 0.919
intracellular protein transport GO:0006886 270 0.917
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 109 0.916
defense response to other organism GO:0098542 129 0.914
viral genome replication GO:0019079 50 0.909
response to cytokine GO:0034097 232 0.905
type i interferon production GO:0032606 27 0.905
posttranscriptional regulation of gene expression GO:0010608 213 0.905
response to external biotic stimulus GO:0043207 261 0.904
response to nitrogen compound GO:1901698 184 0.900
innate immune response activating signal transduction GO:0002758 48 0.893
regulation of viral genome replication GO:0045069 48 0.891
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.889
regulation of defense response GO:0031347 154 0.886
cellular response to organic cyclic compound GO:0071407 127 0.877
gene silencing GO:0016458 49 0.874
regulation of cellular component movement GO:0051270 334 0.872
positive regulation of cytokine production GO:0001819 167 0.871
Mouse
ribonucleoprotein complex subunit organization GO:0071826 81 0.865
regulation of tooth mineralization GO:0070170 3 0.864
negative regulation of multi organism process GO:0043901 92 0.863
establishment of protein localization to organelle GO:0072594 172 0.860
regulation of viral induced cytoplasmic pattern recognition receptor signaling pathway GO:0039531 7 0.845
positive regulation of intracellular protein transport GO:0090316 76 0.840
regulation of response to biotic stimulus GO:0002831 55 0.821
rna processing GO:0006396 255 0.821
activation of innate immune response GO:0002218 55 0.813
protein sumoylation GO:0016925 25 0.800
regulation of mda 5 signaling pathway GO:0039533 4 0.793
positive regulation of type i interferon production GO:0032481 20 0.753
regulation of locomotion GO:0040012 329 0.752
immune effector process GO:0002252 159 0.740
negative regulation of gene silencing by rna GO:0060967 3 0.737
cytoplasmic transport GO:0016482 379 0.735
protein localization to organelle GO:0033365 280 0.732
response to organic cyclic compound GO:0014070 204 0.732
small rna loading onto risc GO:0070922 3 0.720
negative regulation of immune system process GO:0002683 136 0.718
regulation of interferon beta production GO:0032648 22 0.696
protein import into nucleus GO:0006606 104 0.680
positive regulation of multi organism process GO:0043902 56 0.679
regulation of cell migration GO:0030334 289 0.674
rna phosphodiester bond hydrolysis GO:0090501 35 0.644
regulation of odontogenesis GO:0042481 4 0.641
immune response GO:0006955 307 0.639
regulation of gene expression epigenetic GO:0040029 73 0.637
pattern recognition receptor signaling pathway GO:0002221 48 0.620
regulation of immune effector process GO:0002697 91 0.620
cellular response to nitrogen compound GO:1901699 144 0.614
negative regulation of posttranscriptional gene silencing GO:0060149 3 0.595
cytoplasmic pattern recognition receptor signaling pathway in response to virus GO:0039528 8 0.585
interferon beta production GO:0032608 23 0.576
regulation of rig i signaling pathway GO:0039535 6 0.570
negative regulation of defense response to virus by host GO:0050689 4 0.565
single organism cellular localization GO:1902580 332 0.551
intracellular receptor signaling pathway GO:0030522 104 0.547
nuclear transport GO:0051169 179 0.535
negative regulation of multicellular organismal process GO:0051241 317 0.529
hair follicle morphogenesis GO:0031069 2 0.525
regulation of cell motility GO:2000145 299 0.518
negative regulation of defense response GO:0031348 47 0.516
regulation of protein transport GO:0051223 213 0.493
positive regulation of nucleocytoplasmic transport GO:0046824 54 0.487
regulation of intracellular transport GO:0032386 195 0.487
positive regulation of defense response to virus by host GO:0002230 14 0.477
regulation of response to external stimulus GO:0032101 222 0.462
positive regulation of protein import into nucleus GO:0042307 46 0.459
innate immune response GO:0045087 178 0.452
rig i signaling pathway GO:0039529 7 0.444
regulation of protein localization to nucleus GO:1900180 85 0.433
mda 5 signaling pathway GO:0039530 4 0.433
regulation of cellular component biogenesis GO:0044087 281 0.416
Mouse
regulation of protein targeting GO:1903533 91 0.410
positive regulation of protein transport GO:0051222 135 0.392
regulation of nucleocytoplasmic transport GO:0046822 98 0.382
regulation of cell differentiation GO:0045595 393 0.377
Mouse
single organism nuclear import GO:1902593 104 0.361
protein import GO:0017038 130 0.357
defense response GO:0006952 315 0.356
positive regulation of cytoplasmic transport GO:1903651 82 0.354
protein targeting GO:0006605 187 0.347
negative regulation of viral genome replication GO:0045071 35 0.345
protein modification by small protein conjugation GO:0032446 342 0.345
positive regulation of cell death GO:0010942 263 0.344
negative regulation of programmed cell death GO:0043069 321 0.326
Mouse
mrna metabolic process GO:0016071 175 0.313
protein targeting to nucleus GO:0044744 104 0.313
regulation of intracellular protein transport GO:0033157 123 0.309
outer ear morphogenesis GO:0042473 2 0.308
viral transcription GO:0019083 35 0.302
response to exogenous dsrna GO:0043330 10 0.291
mirna loading onto risc involved in gene silencing by mirna GO:0035280 2 0.284
regulation of rna stability GO:0043487 23 0.284
negative regulation of type i interferon production GO:0032480 5 0.274
negative regulation of cell proliferation GO:0008285 228 0.267
positive regulation of viral process GO:0048524 37 0.264
negative regulation of cytokine production GO:0001818 82 0.256
activation of immune response GO:0002253 114 0.246
circulatory system development GO:0072359 262 0.244
nuclear import GO:0051170 106 0.242
regulation of innate immune response GO:0045088 97 0.241
positive regulation of intracellular transport GO:0032388 104 0.236
negative regulation of protein metabolic process GO:0051248 391 0.234
cytokine production GO:0001816 247 0.233
Mouse
positive regulation of gliogenesis GO:0014015 4 0.228
stem cell development GO:0048864 69 0.226
positive regulation of programmed cell death GO:0043068 249 0.221
regulation of protein localization GO:0032880 296 0.218
regulation of interferon alpha production GO:0032647 11 0.218
forebrain generation of neurons GO:0021872 3 0.218
immune response activating signal transduction GO:0002757 90 0.214
negative regulation of viral induced cytoplasmic pattern recognition receptor signaling pathway GO:0039532 3 0.210
positive regulation of rig i signaling pathway GO:1900246 4 0.207
positive regulation of innate immune response GO:0045089 79 0.207
positive regulation of apoptotic process GO:0043065 246 0.203
positive regulation of protein localization to nucleus GO:1900182 48 0.198
cytoplasmic pattern recognition receptor signaling pathway GO:0002753 12 0.189
negative regulation of developmental process GO:0051093 247 0.187
chromatin modification GO:0016568 298 0.186
cardiovascular system development GO:0072358 262 0.183
blood vessel morphogenesis GO:0048514 162 0.182
hindlimb morphogenesis GO:0035137 2 0.177
immune response regulating signaling pathway GO:0002764 97 0.175
mrna processing GO:0006397 133 0.175
stem cell differentiation GO:0048863 93 0.173
Mouse
olfactory bulb interneuron differentiation GO:0021889 2 0.169
cell differentiation in spinal cord GO:0021515 1 0.166
protein localization to nucleus GO:0034504 136 0.162
positive regulation of transport GO:0051050 336 0.161
translation GO:0006412 132 0.160
negative regulation of immune effector process GO:0002698 38 0.160
regulation of translation GO:0006417 89 0.159
negative regulation of response to biotic stimulus GO:0002832 18 0.158
associative learning GO:0008306 1 0.154
negative regulation of immune response GO:0050777 40 0.151
mirna metabolic process GO:0010586 10 0.151
negative regulation of rig i signaling pathway GO:0039536 2 0.149
interferon alpha production GO:0032607 11 0.148
regulation of cytoplasmic transport GO:1903649 149 0.145
chromatin organization GO:0006325 351 0.142
negative regulation of response to external stimulus GO:0032102 83 0.136
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.132
negative regulation of calcium ion import GO:0090281 1 0.130
regulation of protein import into nucleus GO:0042306 78 0.126
angiogenesis GO:0001525 147 0.126
stem cell division GO:0017145 2 0.120
epidermis morphogenesis GO:0048730 3 0.119
cellular response to type i interferon GO:0071357 12 0.118
negative regulation of cell development GO:0010721 48 0.115
central nervous system development GO:0007417 123 0.111
hematopoietic or lymphoid organ development GO:0048534 186 0.111
Mouse
mrna 3 end processing GO:0031124 24 0.109
determination of adult lifespan GO:0008340 2 0.107
apoptotic signaling pathway GO:0097190 268 0.107
positive regulation of immune system process GO:0002684 283 0.107
forebrain neuron differentiation GO:0021879 3 0.106
neural crest cell development GO:0014032 3 0.106
odontogenesis GO:0042476 25 0.105
cellular response to virus GO:0098586 9 0.105
negative regulation of protein ubiquitination GO:0031397 35 0.105
post embryonic development GO:0009791 2 0.103
regulation of transferase activity GO:0051338 355 0.102
negative regulation of catalytic activity GO:0043086 335 0.102
extracellular transport GO:0006858 4 0.101
regulation of cell cycle GO:0051726 393 0.100
atp metabolic process GO:0046034 176 0.099
negative regulation of cell death GO:0060548 345 0.098
Mouse
neurological system process GO:0050877 163 0.098
intrinsic apoptotic signaling pathway GO:0097193 127 0.097
positive regulation of transcription factor import into nucleus GO:0042993 25 0.096
organelle assembly GO:0070925 176 0.095
cell development GO:0048468 328 0.094
nucleocytoplasmic transport GO:0006913 176 0.093
mrna cleavage involved in gene silencing by mirna GO:0035279 2 0.092
regulation of apoptotic signaling pathway GO:2001233 175 0.091
nerve development GO:0021675 4 0.090
regulation of translational initiation in response to stress GO:0043558 1 0.090
negative regulation of binding GO:0051100 57 0.090
multi organism transport GO:0044766 14 0.089
mitotic cell cycle GO:0000278 326 0.087
positive regulation of developmental process GO:0051094 314 0.084
regulation of glial cell differentiation GO:0045685 3 0.083
negative regulation of glial cell proliferation GO:0060253 2 0.083
segmentation GO:0035282 4 0.082
negative regulation of cytosolic calcium ion concentration GO:0051481 1 0.082
regulation of establishment of protein localization GO:0070201 242 0.082
intracellular transport of viral protein in host cell GO:0019060 4 0.081
regulation of viral transcription GO:0046782 34 0.081
nervous system development GO:0007399 293 0.079
negative regulation of cellular protein metabolic process GO:0032269 353 0.078
mrna catabolic process GO:0006402 56 0.078
rna 3 end processing GO:0031123 35 0.077
negative regulation of cell migration GO:0030336 102 0.077
neuromuscular junction development GO:0007528 3 0.076
ventral spinal cord development GO:0021517 1 0.071
mesenchymal cell differentiation GO:0048762 52 0.071
protein autophosphorylation GO:0046777 123 0.070
positive regulation of defense response GO:0031349 87 0.070
cellular component morphogenesis GO:0032989 314 0.070
negative regulation of locomotion GO:0040013 118 0.070
chromatin assembly GO:0031497 61 0.068
stem cell maintenance GO:0019827 19 0.067
regulation of translational initiation GO:0006446 24 0.066
negative regulation of innate immune response GO:0045824 18 0.065
osteoblast differentiation GO:0001649 92 0.065
embryonic morphogenesis GO:0048598 85 0.064
chemical homeostasis GO:0048878 306 0.064
rna phosphodiester bond hydrolysis endonucleolytic GO:0090502 15 0.064
peripheral nervous system development GO:0007422 2 0.063
generation of neurons GO:0048699 152 0.061
regeneration GO:0031099 4 0.060
adenosine to inosine editing GO:0006382 3 0.060
positive regulation of apoptotic signaling pathway GO:2001235 70 0.059
positive regulation of immune response GO:0050778 159 0.059
positive regulation of cellular component organization GO:0051130 376 0.059
cell part morphogenesis GO:0032990 137 0.058
skin development GO:0043588 76 0.057
negative regulation of transport GO:0051051 176 0.056
transcription factor import into nucleus GO:0042991 40 0.056
cellular response to cytokine stimulus GO:0071345 181 0.055
vasculature development GO:0001944 181 0.054
negative regulation of cell differentiation GO:0045596 171 0.054
neuron projection regeneration GO:0031102 1 0.054
multi organism metabolic process GO:0044033 41 0.053
anterior posterior axis specification GO:0009948 2 0.053
trna processing GO:0008033 23 0.052
mesenchymal cell development GO:0014031 50 0.052
regulation of cell development GO:0060284 161 0.052
negative regulation of intracellular signal transduction GO:1902532 183 0.052
ribonucleoside monophosphate metabolic process GO:0009161 187 0.051
mesenchyme development GO:0060485 59 0.051
negative regulation of schwann cell proliferation GO:0010626 1 0.051
regulation of transcription factor import into nucleus GO:0042990 39 0.050
cellular macromolecule catabolic process GO:0044265 380 0.050
regulation by virus of viral protein levels in host cell GO:0046719 4 0.050
cell morphogenesis involved in differentiation GO:0000904 144 0.050
tube development GO:0035295 125 0.050
positive regulation of cell differentiation GO:0045597 211 0.049
memory GO:0007613 3 0.049
regulation of anatomical structure morphogenesis GO:0022603 286 0.048
blastoderm segmentation GO:0007350 2 0.048
spermatid differentiation GO:0048515 4 0.048
ossification GO:0001503 121 0.048
regulation of binding GO:0051098 111 0.047
dna conformation change GO:0071103 113 0.047
translational initiation GO:0006413 48 0.046
reactive oxygen species metabolic process GO:0072593 75 0.046
regulation of neurogenesis GO:0050767 82 0.046
positive regulation of proteolysis GO:0045862 142 0.045
rna catabolic process GO:0006401 71 0.045
regulation of gene silencing GO:0060968 24 0.045
multicellular organismal aging GO:0010259 3 0.045
termination of rna polymerase ii transcription GO:0006369 1 0.044
negative regulation of gliogenesis GO:0014014 3 0.042
viral gene expression GO:0019080 35 0.041
regulation of proteolysis GO:0030162 293 0.041
growth GO:0040007 202 0.041
embryo development GO:0009790 123 0.040
spermatid development GO:0007286 4 0.040
regulation of dna binding GO:0051101 37 0.040
positive regulation of tooth mineralization GO:0070172 2 0.040
embryonic hindlimb morphogenesis GO:0035116 2 0.040
positive regulation of hydrolase activity GO:0051345 331 0.039
response to abiotic stimulus GO:0009628 336 0.039
chromatin assembly or disassembly GO:0006333 78 0.038
regulation of protein complex assembly GO:0043254 147 0.037
Mouse
vesicle mediated transport GO:0016192 371 0.037
dosage compensation GO:0007549 3 0.036
immune system development GO:0002520 195 0.035
Mouse
negative regulation of cellular component movement GO:0051271 106 0.034
cytokine mediated signaling pathway GO:0019221 109 0.033
regulation of cytokine production GO:0001817 232 0.033
Mouse
negative regulation of cell motility GO:2000146 104 0.033
trna metabolic process GO:0006399 35 0.033
epithelial cell differentiation GO:0030855 141 0.033
response to tumor necrosis factor GO:0034612 76 0.033
negative regulation of nervous system development GO:0051961 28 0.032
regulation of nervous system development GO:0051960 88 0.032
cell morphogenesis GO:0000902 296 0.032
nucleic acid transport GO:0050657 39 0.032
long term memory GO:0007616 2 0.032
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.031
intestinal epithelial cell differentiation GO:0060575 3 0.031
nucleoside triphosphate catabolic process GO:0009143 394 0.031
schwann cell development GO:0014044 1 0.031
axon regeneration GO:0031103 1 0.031
epithelium development GO:0060429 227 0.030
negative regulation of transferase activity GO:0051348 124 0.030
protein maturation GO:0051604 233 0.030
cellular amino acid biosynthetic process GO:0008652 30 0.030
snrna metabolic process GO:0016073 15 0.030
skeletal system development GO:0001501 79 0.030
behavior GO:0007610 112 0.030
negative regulation of hydrolase activity GO:0051346 182 0.029
tissue regeneration GO:0042246 3 0.029
nucleoside triphosphate metabolic process GO:0009141 422 0.029
regulation of system process GO:0044057 101 0.029
mrna stabilization GO:0048255 18 0.029
negative regulation of phosphate metabolic process GO:0045936 267 0.029
regulation of protein kinase activity GO:0045859 289 0.029
tube morphogenesis GO:0035239 95 0.029
negative regulation of kinase activity GO:0033673 106 0.029
negative regulation of vasculature development GO:1901343 43 0.029
positive regulation of cell proliferation GO:0008284 301 0.029
zymogen activation GO:0031638 70 0.028
positive regulation of odontogenesis GO:0042482 3 0.028
intracellular protein transport in other organism involved in symbiotic interaction GO:0051708 4 0.028
activation of cysteine type endopeptidase activity GO:0097202 57 0.028
ribonucleoside catabolic process GO:0042454 406 0.028
nucleoside monophosphate metabolic process GO:0009123 191 0.028
epidermis development GO:0008544 59 0.028
protein processing GO:0016485 226 0.028
protein export from nucleus GO:0006611 29 0.027
negative regulation of reactive oxygen species metabolic process GO:2000378 11 0.027
neuron differentiation GO:0030182 138 0.027
response to wounding GO:0009611 168 0.027
regulation of posttranscriptional gene silencing GO:0060147 6 0.027
regulation of angiogenesis GO:0045765 92 0.027
rostrocaudal neural tube patterning GO:0021903 1 0.027
formation of translation preinitiation complex GO:0001731 4 0.027
middle ear morphogenesis GO:0042474 1 0.026
positive regulation of viral genome replication GO:0045070 15 0.026
macrophage fusion GO:0034238 1 0.026
negative regulation of translation GO:0017148 37 0.026
cellular response to oxygen containing compound GO:1901701 276 0.026
primary mirna processing GO:0031053 3 0.026
erythrocyte differentiation GO:0030218 28 0.026
regulation of protein ubiquitination GO:0031396 95 0.025
locomotory behavior GO:0007626 1 0.025
negative regulation of protein kinase activity by regulation of protein phosphorylation GO:0044387 5 0.025
meiotic chromosome segregation GO:0045132 4 0.025
cellular response to dna damage stimulus GO:0006974 379 0.025
positive regulation of glial cell differentiation GO:0045687 2 0.025
positive regulation of intrinsic apoptotic signaling pathway GO:2001244 28 0.025
cognition GO:0050890 43 0.025
positive regulation of response to external stimulus GO:0032103 88 0.025
negative regulation of protein modification process GO:0031400 200 0.025
neuron projection development GO:0031175 106 0.025
positive regulation of cellular amine metabolic process GO:0033240 7 0.024
oocyte differentiation GO:0009994 2 0.024
negative regulation of neurogenesis GO:0050768 26 0.024
negative regulation of phosphorus metabolic process GO:0010563 267 0.024
regulation of glial cell proliferation GO:0060251 4 0.024
negative regulation of cellular component organization GO:0051129 235 0.024
system process GO:0003008 349 0.024
pattern specification process GO:0007389 43 0.023
purine nucleoside monophosphate catabolic process GO:0009128 158 0.023
regulation of cytoskeleton organization GO:0051493 177 0.023
rna stabilization GO:0043489 18 0.023
execution phase of apoptosis GO:0097194 32 0.023
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.022
cellular amino acid metabolic process GO:0006520 116 0.022
positive regulation of nervous system development GO:0051962 54 0.022
heart development GO:0007507 95 0.022
regulation of oocyte development GO:0060281 1 0.022
connective tissue development GO:0061448 39 0.022
response to starvation GO:0042594 59 0.022
regulation of protein binding GO:0043393 66 0.022
anatomical structure formation involved in morphogenesis GO:0048646 284 0.022
positive regulation of mirna metabolic process GO:2000630 4 0.022
neural tube formation GO:0001841 3 0.022
positive regulation of organelle organization GO:0010638 195 0.021
positive regulation of neurological system process GO:0031646 1 0.021
embryonic epithelial tube formation GO:0001838 4 0.021
negative regulation of cell cycle GO:0045786 193 0.021
positive regulation of cellular component biogenesis GO:0044089 158 0.021
purine nucleoside catabolic process GO:0006152 398 0.021
regulation of protein catabolic process GO:0042176 155 0.021
regulation of cellular response to stress GO:0080135 244 0.020
Mouse
regulation of cell maturation GO:1903429 3 0.020
negative regulation of protein phosphorylation GO:0001933 140 0.020
cellular response to tumor necrosis factor GO:0071356 63 0.020
protein oligomerization GO:0051259 173 0.020
erythrocyte homeostasis GO:0034101 31 0.020
secretion by cell GO:0032940 226 0.020
dna templated transcription termination GO:0006353 3 0.020
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 89 0.020
detection of mechanical stimulus GO:0050982 4 0.020
nucleoside phosphate catabolic process GO:1901292 412 0.020
ribonucleoside monophosphate catabolic process GO:0009158 158 0.019
morphogenesis of an epithelium GO:0002009 60 0.019
neurogenesis GO:0022008 169 0.019
negative regulation of growth GO:0045926 97 0.019
regulation of kinase activity GO:0043549 314 0.019
positive regulation of cell development GO:0010720 92 0.019
rna localization GO:0006403 41 0.019
schwann cell differentiation GO:0014037 1 0.019
epithelial cell development GO:0002064 34 0.019
hair cycle GO:0042633 28 0.019
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.019
negative regulation of nf kappab transcription factor activity GO:0032088 51 0.019
dna packaging GO:0006323 77 0.019
reproductive process GO:0022414 106 0.019
retrograde transport endosome to golgi GO:0042147 45 0.019
intracellular transport of virus GO:0075733 14 0.018
cell projection morphogenesis GO:0048858 129 0.018
actin filament based process GO:0030029 224 0.018
symbiont intracellular protein transport in host GO:0030581 4 0.018
negative regulation of phosphorylation GO:0042326 174 0.018
regulation of mapk cascade GO:0043408 262 0.018
rna transport GO:0050658 39 0.018
intracellular steroid hormone receptor signaling pathway GO:0030518 61 0.018
multicellular organismal signaling GO:0035637 34 0.018
protein modification by small protein removal GO:0070646 92 0.018
purine containing compound catabolic process GO:0072523 411 0.017
negative regulation of apoptotic process GO:0043066 316 0.017
Mouse
regulation of cardiac muscle cell proliferation GO:0060043 4 0.017
regulation of neurological system process GO:0031644 6 0.017
digestive tract development GO:0048565 75 0.017
response to nutrient levels GO:0031667 81 0.017
positive regulation of protein complex assembly GO:0031334 86 0.017
protein deubiquitination GO:0016579 79 0.017
response to extracellular stimulus GO:0009991 85 0.017
neuronal action potential GO:0019228 9 0.016
negative regulation of protein binding GO:0032091 35 0.016
nucleotide catabolic process GO:0009166 408 0.016
negative regulation of protein modification by small protein conjugation or removal GO:1903321 41 0.016
neural tube patterning GO:0021532 2 0.016
regulation of cellular component size GO:0032535 82 0.016
muscle cell differentiation GO:0042692 63 0.016
regulation of endothelial cell proliferation GO:0001936 56 0.016
regulation of actin filament length GO:0030832 56 0.016
cellular response to hormone stimulus GO:0032870 125 0.016
urogenital system development GO:0001655 65 0.016
cardiac muscle cell development GO:0055013 5 0.016
cellular component assembly involved in morphogenesis GO:0010927 73 0.015
organ morphogenesis GO:0009887 147 0.015
alditol phosphate metabolic process GO:0052646 3 0.015
regulation of myelination GO:0031641 1 0.015
cardiac muscle tissue development GO:0048738 39 0.015
myeloid cell homeostasis GO:0002262 34 0.015
ncrna 3 end processing GO:0043628 4 0.015
negative regulation of epithelial cell proliferation GO:0050680 48 0.015
oocyte development GO:0048599 1 0.015
purine nucleoside triphosphate metabolic process GO:0009144 412 0.015
definitive hemopoiesis GO:0060216 2 0.015
protein catabolic process GO:0030163 325 0.015
regulation of anatomical structure size GO:0090066 101 0.015
ion homeostasis GO:0050801 230 0.015
positive regulation of phosphorylation GO:0042327 394 0.015
regulation of actin filament based process GO:0032970 141 0.015
regulation of type i interferon production GO:0032479 26 0.015
regulation of biomineral tissue development GO:0070167 31 0.015
regulation of intrinsic apoptotic signaling pathway GO:2001242 72 0.015
ribonucleoside triphosphate metabolic process GO:0009199 412 0.015
nuclear mrna surveillance GO:0071028 4 0.015
carbohydrate derivative biosynthetic process GO:1901137 207 0.014
regulation of neuron differentiation GO:0045664 70 0.014

EIF2AK2 disease predictions

Disease DO term ID Size Probability Func Analog Org
endocrine system disease DOID:28 26 0.110
cancer DOID:162 167 0.029
disease of cellular proliferation DOID:14566 174 0.029
bone disease DOID:0080001 88 0.025
musculoskeletal system disease DOID:17 223 0.025
connective tissue disease DOID:65 109 0.025
aicardi goutieres syndrome DOID:0050629 7 0.022
immune system disease DOID:2914 155 0.021
hematopoietic system disease DOID:74 100 0.021
organ system cancer DOID:0050686 164 0.021
thyroid gland disease DOID:50 11 0.015