Homo sapiens

152 known processes

FBXO5

F-box protein 5

(Aliases: EMI1,FBX5,Fbxo31)

FBXO5 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
protein modification by small protein conjugation GO:0032446 342 0.974
organelle fission GO:0048285 149 0.970
protein ubiquitination GO:0016567 314 0.958
ubiquitin dependent protein catabolic process GO:0006511 206 0.935
mitotic cell cycle process GO:1903047 286 0.923
chromosome segregation GO:0007059 114 0.912
mitotic nuclear division GO:0007067 119 0.884
protein polyubiquitination GO:0000209 110 0.866
nuclear division GO:0000280 128 0.832
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.823
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.818
modification dependent macromolecule catabolic process GO:0043632 212 0.809
mitotic cell cycle GO:0000278 326 0.797
regulation of chromosome segregation GO:0051983 44 0.797
regulation of mitotic metaphase anaphase transition GO:0030071 26 0.773
cellular macromolecule catabolic process GO:0044265 380 0.730
mitotic sister chromatid segregation GO:0000070 53 0.708
cellular protein catabolic process GO:0044257 261 0.707
protein catabolic process GO:0030163 325 0.652
proteasomal protein catabolic process GO:0010498 176 0.646
regulation of proteasomal protein catabolic process GO:0061136 87 0.638
modification dependent protein catabolic process GO:0019941 209 0.632
sister chromatid segregation GO:0000819 54 0.610
negative regulation of mitotic anaphase promoting complex activity GO:0060564 4 0.590
regulation of cell cycle GO:0051726 393 0.554
negative regulation of organelle organization GO:0010639 126 0.529
dna conformation change GO:0071103 113 0.513
regulation of mitotic sister chromatid segregation GO:0033047 27 0.489
regulation of mitotic cell cycle phase transition GO:1901990 118 0.469
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic process GO:0031145 25 0.468
regulation of meiotic cell cycle GO:0051445 4 0.357
Mouse
chromosome separation GO:0051304 23 0.313
regulation of sister chromatid segregation GO:0033045 27 0.308
organelle assembly GO:0070925 176 0.273
Mouse
regulation of mitosis GO:0007088 63 0.261
blastocyst development GO:0001824 3 0.255
chromatin organization GO:0006325 351 0.248
regulation of mitotic cell cycle GO:0007346 189 0.244
negative regulation of cell cycle process GO:0010948 121 0.240
negative regulation of cell cycle GO:0045786 193 0.232
regulation of proteolysis GO:0030162 293 0.216
regulation of protein localization GO:0032880 296 0.211
negative regulation of cellular component organization GO:0051129 235 0.207
mitotic cell cycle phase transition GO:0044772 162 0.206
regulation of cell division GO:0051302 116 0.202
histone modification GO:0016570 251 0.199
microtubule organizing center organization GO:0031023 62 0.185
chromatin modification GO:0016568 298 0.180
dna repair GO:0006281 198 0.179
protein k11 linked ubiquitination GO:0070979 24 0.174
meiotic nuclear division GO:0007126 10 0.172
Mouse
regulation of chromosome organization GO:0033044 103 0.160
regulation of cell cycle process GO:0010564 266 0.155
embryo development GO:0009790 123 0.155
multicellular organismal aging GO:0010259 3 0.153
meiotic chromosome segregation GO:0045132 4 0.141
anatomical structure formation involved in morphogenesis GO:0048646 284 0.139
regulation of transferase activity GO:0051338 355 0.137
regulation of cellular protein catabolic process GO:1903362 96 0.137
purine nucleoside catabolic process GO:0006152 398 0.131
covalent chromatin modification GO:0016569 254 0.130
regulation of nuclear division GO:0051783 65 0.129
oogenesis GO:0048477 2 0.128
Mouse
regulation of protein catabolic process GO:0042176 155 0.125
mitotic sister chromatid separation GO:0051306 18 0.124
post embryonic development GO:0009791 2 0.123
microtubule based process GO:0007017 210 0.118
Mouse
regulation of mitotic sister chromatid separation GO:0010965 27 0.118
small gtpase mediated signal transduction GO:0007264 78 0.115
cell cycle phase transition GO:0044770 173 0.114
cell division GO:0051301 168 0.113
regulation of dna metabolic process GO:0051052 153 0.112
regulation of cytoskeleton organization GO:0051493 177 0.110
microtubule cytoskeleton organization GO:0000226 176 0.108
Mouse
negative regulation of chromosome organization GO:2001251 48 0.098
meiotic cell cycle GO:0051321 13 0.095
Mouse
positive regulation of catabolic process GO:0009896 310 0.092
negative regulation of mitotic cell cycle GO:0045930 102 0.092
regulation of ubiquitin protein transferase activity GO:0051438 28 0.092
cellular response to dna damage stimulus GO:0006974 379 0.091
regulation of cell cycle phase transition GO:1901987 126 0.091
response to abiotic stimulus GO:0009628 336 0.088
negative regulation of cell death GO:0060548 345 0.087
oocyte maturation GO:0001556 1 0.085
Mouse
negative regulation of mitotic cell cycle phase transition GO:1901991 85 0.083
ras protein signal transduction GO:0007265 73 0.083
regulation of microtubule cytoskeleton organization GO:0070507 61 0.082
neurogenesis GO:0022008 169 0.079
Fly
negative regulation of mitotic metaphase anaphase transition GO:0045841 17 0.079
female gamete generation GO:0007292 2 0.073
Mouse
positive regulation of cellular catabolic process GO:0031331 284 0.073
chordate embryonic development GO:0043009 34 0.073
centrosome organization GO:0051297 58 0.073
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 71 0.071
metaphase anaphase transition of cell cycle GO:0044784 21 0.068
negative regulation of developmental process GO:0051093 247 0.068
spindle organization GO:0007051 53 0.067
Mouse
positive regulation of cell cycle GO:0045787 140 0.067
maintenance of location GO:0051235 112 0.066
metaphase anaphase transition of mitotic cell cycle GO:0007091 21 0.066
mitotic cell cycle checkpoint GO:0007093 68 0.065
nervous system development GO:0007399 293 0.063
Fly
purine ribonucleoside metabolic process GO:0046128 437 0.061
positive regulation of cell cycle process GO:0090068 106 0.059
cilium morphogenesis GO:0060271 75 0.058
response to radiation GO:0009314 151 0.058
centrosome cycle GO:0007098 32 0.057
cellular response to oxygen containing compound GO:1901701 276 0.057
regulation of ligase activity GO:0051340 29 0.057
determination of adult lifespan GO:0008340 2 0.057
regulation of protein ubiquitination GO:0031396 95 0.056
purine ribonucleotide catabolic process GO:0009154 404 0.054
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 91 0.054
positive regulation of mitotic cell cycle GO:0045931 60 0.054
nucleoside phosphate catabolic process GO:1901292 412 0.053
regulation of cell differentiation GO:0045595 393 0.052
negative regulation of metaphase anaphase transition of cell cycle GO:1902100 17 0.052
male meiosis GO:0007140 1 0.051
negative regulation of protein metabolic process GO:0051248 391 0.050
reproductive process GO:0022414 106 0.049
Mouse
negative regulation of cell cycle phase transition GO:1901988 89 0.047
ribonucleoside catabolic process GO:0042454 406 0.047
positive regulation of cell proliferation GO:0008284 301 0.045
cardiovascular system development GO:0072358 262 0.044
regulation of response to dna damage stimulus GO:2001020 94 0.044
developmental process involved in reproduction GO:0003006 66 0.043
Mouse
regulation of meiosis GO:0040020 3 0.043
Mouse
positive regulation of organelle organization GO:0010638 195 0.043
negative regulation of protein modification process GO:0031400 200 0.041
tube morphogenesis GO:0035239 95 0.041
negative regulation of programmed cell death GO:0043069 321 0.041
vesicle mediated transport GO:0016192 371 0.040
ribonucleotide catabolic process GO:0009261 405 0.040
internal protein amino acid acetylation GO:0006475 101 0.039
regulation of protein kinase activity GO:0045859 289 0.038
negative regulation of cellular protein catabolic process GO:1903363 38 0.037
positive regulation of protein catabolic process GO:0045732 75 0.036
dna packaging GO:0006323 77 0.035
single organism reproductive process GO:0044702 98 0.035
Mouse
regulation of locomotion GO:0040012 329 0.035
spindle assembly GO:0051225 29 0.034
Mouse
nucleoside catabolic process GO:0009164 408 0.033
mitotic metaphase plate congression GO:0007080 14 0.033
metaphase plate congression GO:0051310 18 0.033
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.032
nucleotide catabolic process GO:0009166 408 0.032
dephosphorylation GO:0016311 209 0.032
reproduction GO:0000003 63 0.032
Mouse
ribosome assembly GO:0042255 9 0.031
dna damage checkpoint GO:0000077 68 0.030
cell morphogenesis GO:0000902 296 0.030
positive regulation of protein ubiquitination GO:0031398 53 0.029
cell projection organization GO:0030030 252 0.029
cell cycle checkpoint GO:0000075 117 0.029
protein localization to organelle GO:0033365 280 0.029
positive regulation of proteolysis GO:0045862 142 0.029
regulation of metaphase anaphase transition of cell cycle GO:1902099 26 0.029
cell development GO:0048468 328 0.029
Mouse
organophosphate catabolic process GO:0046434 430 0.028
dna integrity checkpoint GO:0031570 71 0.028
positive regulation of protein modification by small protein conjugation or removal GO:1903322 61 0.028
cellular response to ionizing radiation GO:0071479 32 0.028
regulation of organelle assembly GO:1902115 40 0.028
atp catabolic process GO:0006200 157 0.027
response to ionizing radiation GO:0010212 65 0.027
negative regulation of apoptotic process GO:0043066 316 0.027
cellular macromolecular complex assembly GO:0034622 324 0.027
Mouse
positive regulation of hydrolase activity GO:0051345 331 0.026
negative regulation of sister chromatid segregation GO:0033046 17 0.026
positive regulation of chromosome organization GO:2001252 41 0.026
histone acetylation GO:0016573 93 0.026
cellular protein complex assembly GO:0043623 188 0.025
Mouse
nucleoside triphosphate catabolic process GO:0009143 394 0.025
purine ribonucleoside catabolic process GO:0046130 398 0.025
double strand break repair GO:0006302 101 0.025
endocytosis GO:0006897 159 0.024
response to oxygen containing compound GO:1901700 369 0.024
dna replication GO:0006260 116 0.024
regulation of cellular response to stress GO:0080135 244 0.024
positive regulation of metaphase anaphase transition of cell cycle GO:1902101 6 0.024
g2 m transition of mitotic cell cycle GO:0000086 41 0.024
posttranscriptional regulation of gene expression GO:0010608 213 0.023
negative regulation of protein phosphorylation GO:0001933 140 0.023
ribonucleoside triphosphate metabolic process GO:0009199 412 0.023
negative regulation of cellular protein metabolic process GO:0032269 353 0.023
negative regulation of mitotic sister chromatid segregation GO:0033048 17 0.023
anatomical structure homeostasis GO:0060249 100 0.023
cellular component morphogenesis GO:0032989 314 0.023
microtubule cytoskeleton organization involved in mitosis GO:1902850 15 0.023
cell adhesion GO:0007155 325 0.022
negative regulation of mitotic sister chromatid separation GO:2000816 17 0.022
negative regulation of catalytic activity GO:0043086 335 0.022
peptidyl lysine acetylation GO:0018394 101 0.022
positive regulation of cellular component organization GO:0051130 376 0.022
cellular amino acid metabolic process GO:0006520 116 0.022
positive regulation of nucleotide metabolic process GO:0045981 230 0.022
embryonic epithelial tube formation GO:0001838 4 0.021
positive regulation of transferase activity GO:0051347 227 0.021
regulation of cellular component movement GO:0051270 334 0.021
reproductive structure development GO:0048608 55 0.021
nucleoside triphosphate metabolic process GO:0009141 422 0.021
nuclear transport GO:0051169 179 0.021
single organism cellular localization GO:1902580 332 0.020
neuron projection development GO:0031175 106 0.020
regulation of dna repair GO:0006282 47 0.020
development of primary sexual characteristics GO:0045137 35 0.020
circulatory system development GO:0072359 262 0.020
negative regulation of mitosis GO:0045839 24 0.020
negative regulation of proteolysis GO:0045861 132 0.020
reproductive system development GO:0061458 56 0.020
negative regulation of cell differentiation GO:0045596 171 0.019
regeneration GO:0031099 4 0.019
cell projection morphogenesis GO:0048858 129 0.019
mitotic spindle checkpoint GO:0071174 18 0.019
cilium assembly GO:0042384 63 0.019
ribonucleoside triphosphate catabolic process GO:0009203 391 0.019
centromeric sister chromatid cohesion GO:0070601 3 0.019
maintenance of location in cell GO:0051651 62 0.019
cell cycle g1 s phase transition GO:0044843 80 0.018
Fly
purine nucleotide catabolic process GO:0006195 405 0.018
regulation of mitotic spindle organization GO:0060236 6 0.018
regulation of chromatin organization GO:1902275 56 0.018
cell part morphogenesis GO:0032990 137 0.017
protein processing GO:0016485 226 0.017
regulation of wnt signaling pathway GO:0030111 123 0.017
microtubule anchoring GO:0034453 24 0.017
regulation of protein stability GO:0031647 87 0.017
embryo development ending in birth or egg hatching GO:0009792 34 0.017
purine nucleoside triphosphate catabolic process GO:0009146 392 0.017
gonad development GO:0008406 34 0.016
regulation of kinase activity GO:0043549 314 0.016
negative regulation of cell division GO:0051782 31 0.016
regulation of double strand break repair GO:2000779 22 0.016
regulation of dna replication GO:0006275 68 0.016
positive regulation of dna metabolic process GO:0051054 73 0.016
regulation of cytoplasmic transport GO:1903649 149 0.016
blood vessel development GO:0001568 172 0.015
meiosis i GO:0007127 4 0.015
Mouse
regulation of cellular amine metabolic process GO:0033238 11 0.015
morphogenesis of embryonic epithelium GO:0016331 4 0.015
cellular response to abiotic stimulus GO:0071214 117 0.015
organelle localization GO:0051640 84 0.015
regulation of small gtpase mediated signal transduction GO:0051056 156 0.015
regulation of spindle organization GO:0090224 10 0.015
response to inorganic substance GO:0010035 127 0.015
positive regulation of mitosis GO:0045840 25 0.015
organophosphate biosynthetic process GO:0090407 163 0.014
glycosyl compound catabolic process GO:1901658 413 0.014
cell cycle g2 m phase transition GO:0044839 43 0.014
positive regulation of proteolysis involved in cellular protein catabolic process GO:1903052 35 0.014
regulation of cell morphogenesis GO:0022604 153 0.014
positive regulation of protein transport GO:0051222 135 0.014
positive regulation of gtp catabolic process GO:0033126 166 0.014
organ morphogenesis GO:0009887 147 0.014
cellular response to radiation GO:0071478 65 0.014
cytokinesis GO:0000910 96 0.014
Zebrafish
carbohydrate derivative biosynthetic process GO:1901137 207 0.013
regulation of intracellular protein transport GO:0033157 123 0.013
regulation of cellular amino acid metabolic process GO:0006521 6 0.013
attachment of spindle microtubules to kinetochore GO:0008608 17 0.013
negative regulation of protein processing GO:0010955 142 0.013
enzyme linked receptor protein signaling pathway GO:0007167 303 0.013
spindle elongation GO:0051231 4 0.013
generation of neurons GO:0048699 152 0.013
positive regulation of nuclear division GO:0051785 27 0.013
receptor mediated endocytosis GO:0006898 84 0.013
negative regulation of ubiquitin protein transferase activity GO:0051444 8 0.013
purine nucleoside triphosphate metabolic process GO:0009144 412 0.013
negative regulation of cellular catabolic process GO:0031330 83 0.013
negative regulation of meiotic cell cycle GO:0051447 2 0.013
Mouse
positive regulation of cell division GO:0051781 59 0.012
cell fate determination GO:0001709 3 0.012
cell projection assembly GO:0030031 126 0.012
neuron differentiation GO:0030182 138 0.012
chromosome localization GO:0050000 20 0.012
sister chromatid cohesion GO:0007062 24 0.012
tissue regeneration GO:0042246 3 0.012
positive regulation of cell death GO:0010942 263 0.012
histone h3 s10 phosphorylation GO:0043987 3 0.012
response to acid chemical GO:0001101 66 0.012
digestive tract development GO:0048565 75 0.012
myeloid cell differentiation GO:0030099 117 0.012
tube development GO:0035295 125 0.011
regulation of cellular ketone metabolic process GO:0010565 50 0.011
protein acetylation GO:0006473 116 0.011
sexual reproduction GO:0019953 37 0.011
Mouse
regulation of protein serine threonine kinase activity GO:0071900 179 0.011
regulation of chromatin modification GO:1903308 51 0.011
regulation of cell motility GO:2000145 299 0.011
sex determination GO:0007530 3 0.011
negative regulation of phosphorus metabolic process GO:0010563 267 0.011
internal peptidyl lysine acetylation GO:0018393 97 0.011
microtubule based movement GO:0007018 32 0.011
negative regulation of multicellular organismal process GO:0051241 317 0.011
nucleoside monophosphate metabolic process GO:0009123 191 0.011
regulation of microtubule based process GO:0032886 74 0.011
response to decreased oxygen levels GO:0036293 96 0.011
neuron development GO:0048666 113 0.011
protein oligomerization GO:0051259 173 0.011
meiotic cell cycle process GO:1903046 8 0.011
Mouse
mitotic dna integrity checkpoint GO:0044774 30 0.011
purine containing compound catabolic process GO:0072523 411 0.011
organelle inheritance GO:0048308 2 0.011
mitotic spindle organization GO:0007052 27 0.010
negative regulation of catabolic process GO:0009895 104 0.010
g1 s transition of mitotic cell cycle GO:0000082 78 0.010
Fly
growth GO:0040007 202 0.010
protein localization to nucleus GO:0034504 136 0.010
response to metal ion GO:0010038 84 0.010
negative regulation of protein maturation GO:1903318 142 0.010
regulation of cellular respiration GO:0043457 4 0.010
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.010
guanosine containing compound metabolic process GO:1901068 244 0.010
positive regulation of meiotic cell cycle GO:0051446 2 0.010
cellular response to endogenous stimulus GO:0071495 336 0.010
sex differentiation GO:0007548 45 0.010
positive regulation of programmed cell death GO:0043068 249 0.010
apoptotic signaling pathway GO:0097190 268 0.010

FBXO5 disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 174 0.042
immune system disease DOID:2914 155 0.024
hematopoietic system disease DOID:74 100 0.024
organ system cancer DOID:0050686 164 0.021
breast cancer DOID:1612 21 0.021
thoracic cancer DOID:5093 21 0.021
cancer DOID:162 167 0.021