Homo sapiens

154 known processes

FGFR1

fibroblast growth factor receptor 1

(Aliases: HBGFR,FLT-2,FGFR-1,CEK,FGFBR,BFGFR,N-SAM,KAL2,bFGF-R-1,OGD,CD331,FLT2,FLG,FLJ99988)

FGFR1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
bud outgrowth involved in lung branching GO:0060447 1 1.000
fibroblast growth factor receptor signaling pathway involved in mammary gland specification GO:0060595 1 1.000
positive regulation of cell fate specification GO:0042660 2 1.000
positive regulation of urothelial cell proliferation GO:0050677 1 1.000
secretion by lung epithelial cell involved in lung growth GO:0061033 2 1.000
regulation of saliva secretion GO:0046877 2 1.000
positive regulation of cardiac muscle cell proliferation GO:0060045 2 1.000
Mouse
ureteric bud elongation GO:0060677 2 1.000
branch elongation involved in ureteric bud branching GO:0060681 2 1.000
specification of organ identity GO:0010092 3 1.000
Mouse
positive regulation of keratinocyte proliferation GO:0010838 4 1.000
mammary gland formation GO:0060592 1 1.000
lung growth GO:0060437 2 1.000
mammary gland specification GO:0060594 1 1.000
negative regulation of fibroblast migration GO:0010764 3 1.000
chondroblast differentiation GO:0060591 2 1.000
tear secretion GO:0070075 1 1.000
positive regulation of lipase activity GO:0060193 28 1.000
positive regulation of phospholipase c activity GO:0010863 13 1.000
organ formation GO:0048645 3 1.000
Mouse
regulation of axon extension involved in axon guidance GO:0048841 2 1.000
lung saccule development GO:0060430 2 0.999
positive regulation of epithelial cell proliferation involved in lung morphogenesis GO:0060501 2 0.999
regulation of epithelial cell proliferation involved in lung morphogenesis GO:2000794 2 0.999
regulation of axon guidance GO:1902667 3 0.999
positive regulation of keratinocyte migration GO:0051549 4 0.999
regulation of urothelial cell proliferation GO:0050675 1 0.999
cardiac muscle cell proliferation GO:0060038 6 0.999
Mouse
epithelial tube branching involved in lung morphogenesis GO:0060441 4 0.999
positive regulation of phospholipase activity GO:0010518 22 0.999
activation of mapk activity GO:0000187 45 0.999
Fly
urothelial cell proliferation GO:0050674 1 0.998
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.998
positive regulation of map kinase activity GO:0043406 80 0.998
positive regulation of hair follicle cell proliferation GO:0071338 1 0.998
regulation of heart growth GO:0060420 4 0.998
Mouse
fibroblast growth factor receptor signaling pathway GO:0008543 26 0.997
circulatory system development GO:0072359 262 0.997
Zebrafish Mouse Fly
regulation of cholesterol metabolic process GO:0090181 4 0.996
epithelial cell proliferation involved in lung morphogenesis GO:0060502 3 0.996
regulation of organ formation GO:0003156 4 0.996
Mouse
forebrain development GO:0030900 26 0.996
Mouse Rat
positive regulation of mapk cascade GO:0043410 190 0.995
erk1 and erk2 cascade GO:0070371 104 0.995
Human
activation of protein kinase activity GO:0032147 90 0.994
Fly
negative regulation of axon extension GO:0030517 2 0.992
Fly
mesodermal cell fate commitment GO:0001710 2 0.990
Mouse Fly
regulation of erk1 and erk2 cascade GO:0070372 99 0.990
Human
regulation of keratinocyte migration GO:0051547 4 0.990
regulation of chemotaxis GO:0050920 74 0.989
regulation of cellular amine metabolic process GO:0033238 11 0.988
stem cell differentiation GO:0048863 93 0.988
Mouse Rat Fly
positive regulation of protein serine threonine kinase activity GO:0071902 119 0.987
positive regulation of blood vessel endothelial cell migration GO:0043536 16 0.986
neuroendocrine cell differentiation GO:0061101 2 0.984
regulation of phospholipase activity GO:0010517 26 0.983
positive regulation of protein kinase activity GO:0045860 190 0.983
positive regulation of cardiac muscle tissue growth GO:0055023 2 0.981
Mouse
regulation of lipase activity GO:0060191 37 0.980
regulation of mapk cascade GO:0043408 262 0.980
organ induction GO:0001759 4 0.980
Mouse
regulation of behavior GO:0050795 82 0.980
regulation of cardiac muscle tissue growth GO:0055021 4 0.978
Mouse
positive regulation of cytosolic calcium ion concentration GO:0007204 82 0.976
lacrimal gland development GO:0032808 2 0.976
stem cell development GO:0048864 69 0.975
Rat
hematopoietic or lymphoid organ development GO:0048534 186 0.975
Fly
regulation of kinase activity GO:0043549 314 0.974
regulation of lipid kinase activity GO:0043550 19 0.973
Human
positive regulation of endothelial cell migration GO:0010595 39 0.973
glycerolipid metabolic process GO:0046486 107 0.972
Human
mesonephros development GO:0001823 17 0.971
Mouse
positive regulation of lipid metabolic process GO:0045834 50 0.971
Human
positive regulation of alcohol biosynthetic process GO:1902932 9 0.971
wnt signaling pathway GO:0016055 156 0.970
cellular response to growth factor stimulus GO:0071363 197 0.970
small molecule biosynthetic process GO:0044283 157 0.967
Human
phospholipid metabolic process GO:0006644 99 0.966
Human
phosphatidylinositol metabolic process GO:0046488 53 0.966
Human
blood vessel development GO:0001568 172 0.965
Mouse
sprouting angiogenesis GO:0002040 29 0.965
blood vessel morphogenesis GO:0048514 162 0.964
Mouse
regulation of anatomical structure morphogenesis GO:0022603 286 0.962
Zebrafish Mouse Fly
positive regulation of wnt signaling pathway GO:0030177 54 0.962
regulation of protein serine threonine kinase activity GO:0071900 179 0.960
vasculature development GO:0001944 181 0.959
Mouse
cell cell signaling GO:0007267 155 0.959
Mouse
positive regulation of phosphorylation GO:0042327 394 0.958
positive regulation of locomotion GO:0040017 186 0.957
canonical wnt signaling pathway GO:0060070 116 0.956
cellular amino acid metabolic process GO:0006520 116 0.956
regulation of locomotion GO:0040012 329 0.955
positive regulation of developmental process GO:0051094 314 0.953
positive regulation of kinase activity GO:0033674 204 0.953
striated muscle cell proliferation GO:0014855 7 0.953
Mouse
cell morphogenesis GO:0000902 296 0.950
Worm Fly
positive regulation of endothelial cell proliferation GO:0001938 37 0.949
cell development GO:0048468 328 0.948
response to growth factor GO:0070848 205 0.948
chemical homeostasis GO:0048878 306 0.947
positive regulation of cholesterol metabolic process GO:0090205 1 0.947
positive regulation of cell motility GO:2000147 177 0.946
positive regulation of lipid kinase activity GO:0090218 13 0.945
Human
glycerophospholipid metabolic process GO:0006650 84 0.944
Human
lung alveolus development GO:0048286 4 0.944
positive regulation of transferase activity GO:0051347 227 0.943
branch elongation of an epithelium GO:0060602 3 0.943
ureteric bud development GO:0001657 13 0.940
Mouse
glycerolipid biosynthetic process GO:0045017 51 0.940
enzyme linked receptor protein signaling pathway GO:0007167 303 0.939
cation homeostasis GO:0055080 189 0.937
regulation of cardiac muscle tissue development GO:0055024 13 0.937
Mouse
epithelium development GO:0060429 227 0.937
Zebrafish Mouse Fly
anatomical structure formation involved in morphogenesis GO:0048646 284 0.937
Zebrafish Mouse Fly
regulation of epithelial cell migration GO:0010632 93 0.937
mapk cascade GO:0000165 288 0.937
post embryonic development GO:0009791 2 0.935
Worm Fly
regulation of canonical wnt signaling pathway GO:0060828 88 0.934
tube morphogenesis GO:0035239 95 0.934
Zebrafish Mouse Worm Fly
peptidyl tyrosine phosphorylation GO:0018108 170 0.934
hindbrain development GO:0030902 3 0.932
regulation of hair follicle cell proliferation GO:0071336 1 0.929
regulation of cellular ketone metabolic process GO:0010565 50 0.928
Human
positive regulation of small gtpase mediated signal transduction GO:0051057 12 0.927
gland morphogenesis GO:0022612 8 0.926
Mouse
tube development GO:0035295 125 0.924
Zebrafish Mouse Worm Fly
positive regulation of tyrosine phosphorylation of stat3 protein GO:0042517 16 0.924
Human
positive regulation of cholesterol biosynthetic process GO:0045542 1 0.919
cellular amine metabolic process GO:0044106 41 0.919
organophosphate biosynthetic process GO:0090407 163 0.917
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.911
steroid biosynthetic process GO:0006694 46 0.910
Human
positive regulation of lipid biosynthetic process GO:0046889 22 0.909
immune system development GO:0002520 195 0.907
Fly
actin filament based process GO:0030029 224 0.904
regulation of fibroblast migration GO:0010762 7 0.902
cardiovascular system development GO:0072358 262 0.901
Zebrafish Mouse Fly
lipid metabolic process GO:0006629 381 0.900
Human
steroid metabolic process GO:0008202 94 0.898
Human
cell activation GO:0001775 213 0.898
angiogenesis GO:0001525 147 0.898
Mouse
regulation of transferase activity GO:0051338 355 0.897
regulation of cell development GO:0060284 161 0.894
positive regulation of organ growth GO:0046622 2 0.894
Mouse
organ morphogenesis GO:0009887 147 0.893
Human Zebrafish Mouse Fly
neuron projection development GO:0031175 106 0.892
Mouse Rat Worm Fly
cardiac muscle tissue development GO:0048738 39 0.891
Zebrafish Mouse
metanephros development GO:0001656 16 0.888
cell migration involved in sprouting angiogenesis GO:0002042 19 0.885
leukocyte activation GO:0045321 164 0.885
positive regulation of ossification GO:0045778 32 0.882
lung epithelium development GO:0060428 7 0.880
axis elongation GO:0003401 4 0.879
regulation of map kinase activity GO:0043405 108 0.879
regulation of protein kinase activity GO:0045859 289 0.876
regulation of cell differentiation GO:0045595 393 0.875
regulation of cellular component movement GO:0051270 334 0.875
positive regulation of angiogenesis GO:0045766 51 0.875
regulation of cell projection organization GO:0031344 107 0.875
Mouse Rat Worm Fly
fibroblast migration GO:0010761 7 0.875
cellular ion homeostasis GO:0006873 168 0.870
regulation of extent of cell growth GO:0061387 9 0.870
Fly
small gtpase mediated signal transduction GO:0007264 78 0.869
ras protein signal transduction GO:0007265 73 0.866
prostate gland morphogenesis GO:0060512 1 0.865
organic hydroxy compound biosynthetic process GO:1901617 71 0.862
Human
regulation of cell morphogenesis GO:0022604 153 0.860
Fly
positive regulation of cellular amine metabolic process GO:0033240 7 0.860
sequestering of calcium ion GO:0051208 17 0.859
morphogenesis of a branching structure GO:0001763 21 0.858
Mouse Fly
regulation of steroid metabolic process GO:0019218 32 0.858
Human
cellular response to endogenous stimulus GO:0071495 336 0.857
regulation of angiogenesis GO:0045765 92 0.856
connective tissue development GO:0061448 39 0.855
Mouse
regulation of endothelial cell migration GO:0010594 67 0.855
nucleotide catabolic process GO:0009166 408 0.854
kidney epithelium development GO:0072073 25 0.853
Mouse
secretion by cell GO:0032940 226 0.853
Worm
positive regulation of cyclin dependent protein serine threonine kinase activity GO:0045737 15 0.851
regulation of keratinocyte proliferation GO:0010837 11 0.848
nephron morphogenesis GO:0072028 15 0.847
positive regulation of cellular component movement GO:0051272 181 0.847
positive regulation of osteoblast differentiation GO:0045669 23 0.846
positive regulation of muscle organ development GO:0048636 7 0.843
Mouse
mesonephric epithelium development GO:0072163 14 0.841
Mouse
regulation of nucleotide catabolic process GO:0030811 205 0.841
glycosyl compound catabolic process GO:1901658 413 0.840
kidney morphogenesis GO:0060993 19 0.840
regulation of neurogenesis GO:0050767 82 0.839
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.839
axon extension involved in axon guidance GO:0048846 5 0.838
glycerophospholipid biosynthetic process GO:0046474 40 0.837
negative regulation of wound healing GO:0061045 25 0.835
negative regulation of cell cycle process GO:0010948 121 0.834
positive regulation of steroid biosynthetic process GO:0010893 6 0.833
metal ion homeostasis GO:0055065 169 0.832
cytosolic calcium ion homeostasis GO:0051480 89 0.831
regulation of organ morphogenesis GO:2000027 24 0.827
Mouse
glial cell migration GO:0008347 4 0.825
Fly
positive regulation of cell division GO:0051781 59 0.825
muscle cell proliferation GO:0033002 35 0.825
Mouse
hemopoiesis GO:0030097 180 0.823
cellular component morphogenesis GO:0032989 314 0.822
Worm Fly
regulation of steroid biosynthetic process GO:0050810 23 0.820
Human
pituitary gland development GO:0021983 2 0.820
positive regulation of epithelial cell proliferation GO:0050679 65 0.817
cellular response to dna damage stimulus GO:0006974 379 0.815
lipid biosynthetic process GO:0008610 177 0.812
Human
chemotaxis GO:0006935 157 0.812
Worm
cellular calcium ion homeostasis GO:0006874 117 0.811
lung morphogenesis GO:0060425 6 0.810
cell projection organization GO:0030030 252 0.804
Mouse Rat Worm Fly
developmental programmed cell death GO:0010623 3 0.798
regulation of cellular amino acid metabolic process GO:0006521 6 0.796
divalent inorganic cation homeostasis GO:0072507 136 0.795
regulation of wnt signaling pathway GO:0030111 123 0.791
secretion GO:0046903 254 0.788
Worm
regulation of peptidyl tyrosine phosphorylation GO:0050730 108 0.787
Human
regulation of epithelial cell proliferation GO:0050678 113 0.787
forebrain generation of neurons GO:0021872 3 0.787
Mouse Rat
negative regulation of epithelial cell migration GO:0010633 38 0.787
behavior GO:0007610 112 0.784
Worm
system process GO:0003008 349 0.784
Mouse Rat
cell type specific apoptotic process GO:0097285 125 0.784
epithelial cell migration GO:0010631 119 0.778
Fly
endothelial cell proliferation GO:0001935 65 0.772
male gonad development GO:0008584 23 0.769
alcohol metabolic process GO:0006066 114 0.762
purine ribonucleotide catabolic process GO:0009154 404 0.758
regulation of sequestering of calcium ion GO:0051282 41 0.753
calcium ion homeostasis GO:0055074 122 0.753
regulation of purine nucleotide catabolic process GO:0033121 205 0.745
ion homeostasis GO:0050801 230 0.743
generation of neurons GO:0048699 152 0.739
purine nucleoside triphosphate metabolic process GO:0009144 412 0.737
endothelial cell migration GO:0043542 86 0.734
epithelial cell differentiation GO:0030855 141 0.728
Mouse Fly
peptidyl tyrosine modification GO:0018212 170 0.726
negative regulation of developmental process GO:0051093 247 0.724
Zebrafish Rat Fly
limb bud formation GO:0060174 1 0.724
dna replication GO:0006260 116 0.724
purine nucleotide catabolic process GO:0006195 405 0.722
digestive system development GO:0055123 75 0.720
Zebrafish Mouse Worm Fly
hair follicle morphogenesis GO:0031069 2 0.719
ribonucleoside triphosphate catabolic process GO:0009203 391 0.719
mesonephric tubule morphogenesis GO:0072171 10 0.717
neuromuscular junction development GO:0007528 3 0.717
regulation of neuron projection development GO:0010975 57 0.713
Mouse Rat Fly
positive regulation of phosphatidylinositol 3 kinase activity GO:0043552 12 0.706
Human
gland development GO:0048732 48 0.706
Zebrafish Mouse Fly
response to wounding GO:0009611 168 0.705
Zebrafish
positive regulation of protein phosphorylation GO:0001934 313 0.704
lung associated mesenchyme development GO:0060484 1 0.702
Mouse
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.702
cellular response to oxygen containing compound GO:1901701 276 0.700
positive regulation of neural precursor cell proliferation GO:2000179 2 0.700
positive regulation of cell proliferation GO:0008284 301 0.694
axon extension GO:0048675 13 0.692
Fly
positive regulation of nucleoside metabolic process GO:0045979 186 0.691
cell cell signaling involved in cell fate commitment GO:0045168 5 0.690
Mouse
regulation of cell morphogenesis involved in differentiation GO:0010769 83 0.689
Fly
regulation of cell migration GO:0030334 289 0.687
positive regulation of protein kinase b signaling GO:0051897 42 0.685
neurogenesis GO:0022008 169 0.684
regulation of cardiac muscle cell proliferation GO:0060043 4 0.683
Mouse
embryonic organ morphogenesis GO:0048562 24 0.678
Human Mouse
regulation of endothelial cell proliferation GO:0001936 56 0.674
neuroblast proliferation GO:0007405 4 0.674
Mouse
positive regulation of steroid metabolic process GO:0045940 13 0.670
regulation of cyclin dependent protein serine threonine kinase activity GO:0000079 36 0.669
nephron epithelium morphogenesis GO:0072088 15 0.666
cellular ketone metabolic process GO:0042180 80 0.665
Human
developmental induction GO:0031128 5 0.665
Mouse
negative regulation of multicellular organismal process GO:0051241 317 0.660
Zebrafish Rat Fly
nervous system development GO:0007399 293 0.660
positive regulation of cellular catabolic process GO:0031331 284 0.654
ureteric bud morphogenesis GO:0060675 10 0.652
branching involved in ureteric bud morphogenesis GO:0001658 9 0.651
positive chemotaxis GO:0050918 33 0.650
cellular metal ion homeostasis GO:0006875 146 0.649
organic hydroxy compound metabolic process GO:1901615 147 0.649
Human
regulation of smooth muscle cell proliferation GO:0048660 28 0.645
drinking behavior GO:0042756 1 0.641
positive regulation of canonical wnt signaling pathway GO:0090263 33 0.640
embryo development GO:0009790 123 0.639
Human Zebrafish Mouse Worm Fly
regulation of nucleoside metabolic process GO:0009118 209 0.638
lymphocyte activation GO:0046649 133 0.637
branching morphogenesis of an epithelial tube GO:0048754 19 0.636
Fly
regulation of ras protein signal transduction GO:0046578 155 0.633
neuron projection extension GO:1990138 14 0.630
Fly
positive regulation of cell differentiation GO:0045597 211 0.627
protein autophosphorylation GO:0046777 123 0.627
polyol metabolic process GO:0019751 32 0.626
regulation of nervous system development GO:0051960 88 0.626
regulation of cell motility GO:2000145 299 0.623
positive regulation of epithelial cell migration GO:0010634 55 0.623
epithelial cell proliferation GO:0050673 128 0.622
mammary gland morphogenesis GO:0060443 2 0.621
regulation of metalloenzyme activity GO:0048552 3 0.619
Human
kidney development GO:0001822 53 0.619
Mouse
immune response GO:0006955 307 0.616
Fly
divalent metal ion transport GO:0070838 152 0.615
head development GO:0060322 108 0.600
Mouse Rat
regulation of dna metabolic process GO:0051052 153 0.599
Human
cellular divalent inorganic cation homeostasis GO:0072503 128 0.595
positive regulation of cell migration GO:0030335 172 0.588
positive regulation of programmed cell death GO:0043068 249 0.586
regulation of vasculature development GO:1901342 97 0.586
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.585
locomotory behavior GO:0007626 1 0.583
cell projection morphogenesis GO:0048858 129 0.581
Worm Fly
segmentation GO:0035282 4 0.579
cell part morphogenesis GO:0032990 137 0.578
Worm Fly
regulation of blood vessel endothelial cell migration GO:0043535 30 0.575
mitotic cell cycle process GO:1903047 286 0.575
cation transport GO:0006812 331 0.574
keratinocyte proliferation GO:0043616 17 0.574
purine nucleoside catabolic process GO:0006152 398 0.573
negative regulation of cell death GO:0060548 345 0.572
regulation of body fluid levels GO:0050878 99 0.570
cellular cation homeostasis GO:0030003 163 0.569
regulation of mitotic cell cycle GO:0007346 189 0.568
regulation of cellular response to stress GO:0080135 244 0.566
glandular epithelial cell differentiation GO:0002067 6 0.561
blastoderm segmentation GO:0007350 2 0.556
defense response to other organism GO:0098542 129 0.553
Fly
positive regulation of cyclin dependent protein serine threonine kinase activity involved in g1 s transition of mitotic cell cycle GO:0031659 8 0.552
positive regulation of nucleotide metabolic process GO:0045981 230 0.551
monocarboxylic acid metabolic process GO:0032787 185 0.551
Human
signal transduction by phosphorylation GO:0023014 297 0.549
single organism reproductive process GO:0044702 98 0.539
Worm Fly
negative regulation of cellular component organization GO:0051129 235 0.539
Fly
axon development GO:0061564 34 0.535
Worm Fly
purine ribonucleoside catabolic process GO:0046130 398 0.531
skin development GO:0043588 76 0.529
Zebrafish Mouse
negative regulation of axonogenesis GO:0050771 4 0.529
Fly
blood vessel endothelial cell migration GO:0043534 42 0.528
regulation of muscle organ development GO:0048634 27 0.519
Mouse
regulation of cholesterol biosynthetic process GO:0045540 3 0.518
nucleoside phosphate catabolic process GO:1901292 412 0.517
positive regulation of catabolic process GO:0009896 310 0.517
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.516
mucopolysaccharide metabolic process GO:1903510 27 0.515
regulation of osteoblast differentiation GO:0045667 38 0.511
Rat
regulation of phosphatidylinositol 3 kinase activity GO:0043551 14 0.500
Human
regulation of phospholipase c activity GO:1900274 14 0.497
midbrain development GO:0030901 45 0.496
Mouse
forebrain neuron development GO:0021884 2 0.495
Rat
sensory organ morphogenesis GO:0090596 21 0.492
Mouse
rap protein signal transduction GO:0032486 7 0.488
central nervous system development GO:0007417 123 0.488
Mouse Rat Fly
neuron differentiation GO:0030182 138 0.485
regulation of nucleotide metabolic process GO:0006140 269 0.483
leukocyte proliferation GO:0070661 74 0.480
branching involved in salivary gland morphogenesis GO:0060445 1 0.480
Mouse
brain development GO:0007420 97 0.475
Mouse Rat
regulation of system process GO:0044057 101 0.475
Rat
regulation of cell fate commitment GO:0010453 7 0.468
Zebrafish Mouse
positive regulation of cellular component organization GO:0051130 376 0.466
Mouse Rat
regulation of ion homeostasis GO:2000021 73 0.465
nucleoside catabolic process GO:0009164 408 0.465
heart growth GO:0060419 6 0.465
Mouse
positive regulation of nucleotide catabolic process GO:0030813 185 0.465
regulation of cyclin dependent protein serine threonine kinase activity involved in g1 s transition of mitotic cell cycle GO:0031657 9 0.462
actin cytoskeleton organization GO:0030036 207 0.462
negative regulation of cell projection organization GO:0031345 22 0.460
Fly
negative regulation of apoptotic process GO:0043066 316 0.460
nucleoside triphosphate catabolic process GO:0009143 394 0.459
ribonucleoside triphosphate metabolic process GO:0009199 412 0.458
negative regulation of cell proliferation GO:0008285 228 0.457
female gamete generation GO:0007292 2 0.457
Fly
nephron tubule development GO:0072080 17 0.453
purine nucleoside triphosphate catabolic process GO:0009146 392 0.451
taxis GO:0042330 157 0.448
Worm
metal ion transport GO:0030001 272 0.447
cellular response to organic cyclic compound GO:0071407 127 0.441
endocrine system development GO:0035270 26 0.438
nephron epithelium development GO:0072009 23 0.435
response to fibroblast growth factor GO:0071774 39 0.434
activation of mapkk activity GO:0000186 18 0.433
detection of mechanical stimulus GO:0050982 4 0.431
response to organonitrogen compound GO:0010243 156 0.428
positive regulation of neurogenesis GO:0050769 49 0.425
tissue migration GO:0090130 119 0.424
Fly
alcohol biosynthetic process GO:0046165 52 0.423
response to abiotic stimulus GO:0009628 336 0.421
response to organic cyclic compound GO:0014070 204 0.420
positive regulation of dna metabolic process GO:0051054 73 0.419
Human
extrinsic apoptotic signaling pathway GO:0097191 119 0.418
Human Mouse
regulation of homeostatic process GO:0032844 121 0.417
neuron projection extension involved in neuron projection guidance GO:1902284 5 0.416
axonogenesis GO:0007409 31 0.415
Worm Fly
embryonic camera type eye development GO:0031076 2 0.412
regulation of wound healing GO:0061041 56 0.409
negative regulation of programmed cell death GO:0043069 321 0.409
response to biotic stimulus GO:0009607 276 0.408
Fly
regulation of growth GO:0040008 165 0.408
Mouse Fly
regulation of lymphocyte proliferation GO:0050670 64 0.406
regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 9 0.399
oogenesis GO:0048477 2 0.396
Fly
innate immune response GO:0045087 178 0.394
Fly
regulation of cell cycle process GO:0010564 266 0.392
rho protein signal transduction GO:0007266 26 0.390
mononuclear cell proliferation GO:0032943 71 0.389
positive regulation of dna replication GO:0045740 35 0.388
positive regulation of atpase activity GO:0032781 19 0.383
response to inorganic substance GO:0010035 127 0.382
cell morphogenesis involved in differentiation GO:0000904 144 0.382
Worm Fly
phosphatidylinositol biosynthetic process GO:0006661 25 0.381
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.379
Mouse
embryonic camera type eye formation GO:0060900 2 0.378
amine metabolic process GO:0009308 44 0.376
regulation of organ growth GO:0046620 7 0.374
Mouse
response to axon injury GO:0048678 1 0.374
regulation of neuron differentiation GO:0045664 70 0.373
ribonucleoside monophosphate catabolic process GO:0009158 158 0.373
cell growth GO:0016049 160 0.372
Fly
atp catabolic process GO:0006200 157 0.372
cytoplasmic transport GO:0016482 379 0.370
regulation of axon extension GO:0030516 7 0.369
Fly
cell cycle phase transition GO:0044770 173 0.369
positive regulation of muscle tissue development GO:1901863 7 0.368
Mouse
neuron development GO:0048666 113 0.365
Mouse Rat Worm Fly
regulation of response to external stimulus GO:0032101 222 0.359
ribonucleoside catabolic process GO:0042454 406 0.356
regulation of atpase activity GO:0043462 25 0.354
keratinocyte migration GO:0051546 6 0.354
neuron projection morphogenesis GO:0048812 50 0.353
Worm Fly
membrane organization GO:0061024 292 0.352
Worm
epidermis morphogenesis GO:0048730 3 0.352
morphogenesis of a branching epithelium GO:0061138 20 0.351
Mouse Fly
regulation of cell cycle arrest GO:0071156 36 0.349
response to purine containing compound GO:0014074 40 0.348
regulation of anatomical structure size GO:0090066 101 0.347
Fly
lens development in camera type eye GO:0002088 2 0.347
cellular chemical homeostasis GO:0055082 180 0.345
cell fate commitment GO:0045165 27 0.344
Zebrafish Mouse Fly
cellular response to heat GO:0034605 14 0.344
gtp catabolic process GO:0006184 237 0.343
digestive tract development GO:0048565 75 0.342
Zebrafish Mouse Worm Fly
negative regulation of endothelial cell migration GO:0010596 29 0.342
defense response GO:0006952 315 0.341
Fly
regulation of establishment of protein localization GO:0070201 242 0.339
developmental cell growth GO:0048588 18 0.337
Fly
nephron tubule morphogenesis GO:0072078 13 0.337
response to external biotic stimulus GO:0043207 261 0.336
Fly
negative regulation of cell cycle GO:0045786 193 0.336
stem cell division GO:0017145 2 0.334
Mouse
g1 s transition of mitotic cell cycle GO:0000082 78 0.333
tyrosine phosphorylation of stat3 protein GO:0042503 20 0.329
Human
positive regulation of cell fate commitment GO:0010455 2 0.327
regulation of tyrosine phosphorylation of stat protein GO:0042509 30 0.327
Human
cellular homeostasis GO:0019725 196 0.316
lung development GO:0030324 20 0.315
Mouse
reproductive system development GO:0061458 56 0.314
Worm Fly
neural precursor cell proliferation GO:0061351 6 0.314
Mouse
morphogenesis of embryonic epithelium GO:0016331 4 0.312
positive regulation of heart growth GO:0060421 2 0.311
Mouse
positive regulation of jak stat cascade GO:0046427 35 0.311
Human
negative regulation of cell differentiation GO:0045596 171 0.311
Zebrafish Rat Fly
renal system development GO:0072001 63 0.310
Mouse Fly
regulation of synaptic plasticity GO:0048167 3 0.310
calcium ion transport into cytosol GO:0060402 48 0.307
negative regulation of cell cycle arrest GO:0071157 12 0.307
tripartite regional subdivision GO:0007351 2 0.307
protein kinase b signaling GO:0043491 69 0.306
regulation of protein transport GO:0051223 213 0.304
eye development GO:0001654 42 0.303
morphogenesis of an epithelium GO:0002009 60 0.303
Zebrafish Mouse Fly
response to temperature stimulus GO:0009266 22 0.301
regulation of axonogenesis GO:0050770 16 0.298
Fly
phospholipid biosynthetic process GO:0008654 44 0.297
purine nucleoside monophosphate catabolic process GO:0009128 158 0.297
striated muscle cell differentiation GO:0051146 43 0.297
Fly
reproductive process GO:0022414 106 0.295
Worm Fly
regulation of transporter activity GO:0032409 82 0.294
cellular response to fibroblast growth factor stimulus GO:0044344 39 0.293
regulation of response to dna damage stimulus GO:2001020 94 0.292
cartilage development GO:0051216 31 0.292
Mouse
gastrulation with mouth forming second GO:0001702 1 0.291
heart development GO:0007507 95 0.284
Zebrafish Mouse Fly
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.282
inorganic cation transmembrane transport GO:0098662 194 0.281
regulation of dna repair GO:0006282 47 0.280
regulation of neural precursor cell proliferation GO:2000177 4 0.277
nerve development GO:0021675 4 0.276
Zebrafish
cell cycle arrest GO:0007050 71 0.273
detection of stimulus GO:0051606 85 0.272
outflow tract septum morphogenesis GO:0003148 4 0.271

FGFR1 disease predictions

Disease DO term ID Size Probability Func Analog Org
vascular disease DOID:178 25 0.903
Human
cardiovascular system disease DOID:1287 106 0.903
Human
cancer DOID:162 167 0.853
Human
disease of cellular proliferation DOID:14566 174 0.853
Human
organ system cancer DOID:0050686 164 0.853
Human