IMP

Process View

Homo sapiens

13 genes annotated in human

nephron tubule morphogenesis

GO:0072078

The process in which the anatomical structures of a nephron tubule are generated and organized. A nephron tubule is an epithelial tube that is part of the nephron, the functional part of the kidney.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "nephron tubule morphogenesis"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "nephron tubule morphogenesis" (in gray)

Name	Description	Probability	Func Analog Organism
FGFR2	fibroblast growth factor receptor 2	1.000
FLT1	fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)	0.954
FSTL1	follistatin-like 1	0.876
NR4A1	nuclear receptor subfamily 4, group A, member 1	0.876
EGR1	early growth response 1	0.874	Human
FGF10	fibroblast growth factor 10	0.793	Human
FGF1	fibroblast growth factor 1 (acidic)	0.789
KLHL3	kelch-like 3 (Drosophila)	0.782
VEGFA	vascular endothelial growth factor A	0.769	Mouse
EGR3	early growth response 3	0.717	Human
WNK4	WNK lysine deficient protein kinase 4	0.700
BMPR1A	bone morphogenetic protein receptor, type IA	0.688
KLHL12	kelch-like 12 (Drosophila)	0.624	Human
CUL3	cullin 3	0.619
DAPK1	death-associated protein kinase 1	0.601
EGR2	early growth response 2	0.573	Human
MEIS1	Meis homeobox 1	0.567
PKD2	polycystic kidney disease 2 (autosomal dominant)	0.480
MEOX1	mesenchyme homeobox 1	0.425
PKD1	polycystic kidney disease 1 (autosomal dominant)	0.402
MEIS2	Meis homeobox 2	0.398
FGFR1	fibroblast growth factor receptor 1	0.337
FGF8	fibroblast growth factor 8 (androgen-induced)	0.306
NKX2-1	NK2 homeobox 1	0.292
SKIL	SKI-like oncogene	0.284
TSC22D4	TSC22 domain family, member 4	0.257
SMAD3	SMAD family member 3	0.221
ADAM17	ADAM metallopeptidase domain 17	0.182
PJA1	praja ring finger 1	0.159
FGF4	fibroblast growth factor 4	0.152	Human
DVL3	dishevelled, dsh homolog 3 (Drosophila)	0.146
PGF	placental growth factor	0.145	Mouse
MSN	moesin	0.144
NEDD4L	neural precursor cell expressed, developmentally down-regulated 4-like	0.142
KLHL2	kelch-like 2, Mayven (Drosophila)	0.142	Human
WNT1	wingless-type MMTV integration site family, member 1	0.140	Human Mouse Fly
SMAD2	SMAD family member 2	0.140
GLIS2	GLIS family zinc finger 2	0.129
HOXB5	homeobox B5	0.119
CACNA1G	calcium channel, voltage-dependent, T type, alpha 1G subunit	0.117
FGF3	fibroblast growth factor 3	0.117	Human
FOSB	FBJ murine osteosarcoma viral oncogene homolog B	0.109
COL2A1	collagen, type II, alpha 1	0.101
MAGED2	melanoma antigen family D, 2	0.100
FGF18	fibroblast growth factor 18	0.099
HOXA10	homeobox A10	0.097
NRP1	neuropilin 1	0.095
TAOK1	TAO kinase 1	0.094
BCL2L1	BCL2-like 1	0.091
NR4A2	nuclear receptor subfamily 4, group A, member 2	0.087
MDM2	Mdm2 p53 binding protein homolog (mouse)	0.083
BMP7	bone morphogenetic protein 7	0.083
TGFBR2	transforming growth factor, beta receptor II (70/80kDa)	0.074
PAX8	paired box 8	0.073
CEBPB	CCAAT/enhancer binding protein (C/EBP), beta	0.062
FOXC2	forkhead box C2 (MFH-1, mesenchyme forkhead 1)	0.060
NR4A3	nuclear receptor subfamily 4, group A, member 3	0.057
FOS	FBJ murine osteosarcoma viral oncogene homolog	0.051
TIMP3	TIMP metallopeptidase inhibitor 3	0.050
TP53	tumor protein p53	0.048
PAX3	paired box 3	0.045
SOX1	SRY (sex determining region Y)-box 1	0.044
TGFBR1	transforming growth factor, beta receptor 1	0.042
SFRP1	secreted frizzled-related protein 1	0.039
NOTCH1	notch 1	0.038
IER2	immediate early response 2	0.038
ENG	endoglin	0.037
KDR	kinase insert domain receptor (a type III receptor tyrosine kinase)	0.036
FGFR3	fibroblast growth factor receptor 3	0.033
LBX1	ladybird homeobox 1	0.033
MDFI	MyoD family inhibitor	0.033
WFIKKN2	WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2	0.031
HES2	hairy and enhancer of split 2 (Drosophila)	0.027
CLDN4	claudin 4	0.027
HOXB6	homeobox B6	0.026
HOXA11	homeobox A11	0.026	Mouse
TRPC1	transient receptor potential cation channel, subfamily C, member 1	0.026
ZNF331	zinc finger protein 331	0.025
HOXD13	homeobox D13	0.025
HNF1A	HNF1 homeobox A	0.025
HMGA2	high mobility group AT-hook 2	0.024
NFE2L2	nuclear factor (erythroid-derived 2)-like 2	0.024
FOXA2	forkhead box A2	0.023
BMP2	bone morphogenetic protein 2	0.023	Human Mouse
GDNF	glial cell derived neurotrophic factor	0.022
FGF7	fibroblast growth factor 7	0.021	Human
BBS1	Bardet-Biedl syndrome 1	0.021
ZFP36	zinc finger protein 36, C3H type, homolog (mouse)	0.021
TAL1	T-cell acute lymphocytic leukemia 1	0.021
SIM2	single-minded homolog 2 (Drosophila)	0.021
ZFYVE9	zinc finger, FYVE domain containing 9	0.021
INHBB	inhibin, beta B	0.021
NKX2-5	NK2 transcription factor related, locus 5 (Drosophila)	0.020
PAX7	paired box 7	0.020
FOXL1	forkhead box L1	0.019
SKI	v-ski sarcoma viral oncogene homolog (avian)	0.019
PAX2	paired box 2	0.019
BHLHE40	basic helix-loop-helix family, member e40	0.018
SLC3A2	solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2	0.018
PTPRB	protein tyrosine phosphatase, receptor type, B	0.018
CASK	calcium/calmodulin-dependent serine protein kinase (MAGUK family)	0.018
TGFB2	transforming growth factor, beta 2	0.018
NAB2	NGFI-A binding protein 2 (EGR1 binding protein 2)	0.018
SNAI1	snail homolog 1 (Drosophila)	0.018
OXSR1	oxidative-stress responsive 1	0.017
LMO4	LIM domain only 4	0.016
FOXC1	forkhead box C1	0.016
NOG	noggin	0.016	Mouse
ARAF	v-raf murine sarcoma 3611 viral oncogene homolog	0.015
DVL1	dishevelled, dsh homolog 1 (Drosophila)	0.015
ZNF512B	zinc finger protein 512B	0.015
EYA2	eyes absent homolog 2 (Drosophila)	0.015
AXIN1	axin 1	0.015
SIX2	SIX homeobox 2	0.015	Mouse
BHLHE23	basic helix-loop-helix family, member e23	0.015
WNT3	wingless-type MMTV integration site family, member 3	0.014	Human
BMP4	bone morphogenetic protein 4	0.014
PARVA	parvin, alpha	0.014
RUNX1	runt-related transcription factor 1	0.014
DLX4	distal-less homeobox 4	0.014
NEUROG2	neurogenin 2	0.014
FOXF1	forkhead box F1	0.013
HOXC5	homeobox C5	0.013
JAG1	jagged 1	0.013
RSPO2	R-spondin 2 homolog (Xenopus laevis)	0.013
MNX1	motor neuron and pancreas homeobox 1	0.013
TBX5	T-box 5	0.013
ID4	inhibitor of DNA binding 4, dominant negative helix-loop-helix protein	0.013
VSX1	visual system homeobox 1	0.013
IRX4	iroquois homeobox 4	0.012
RAX	retina and anterior neural fold homeobox	0.012
MAFG	v-maf musculoaponeurotic fibrosarcoma oncogene homolog G (avian)	0.012
WNT7A	wingless-type MMTV integration site family, member 7A	0.012	Human
HOXB1	homeobox B1	0.011
TAGLN2	transgelin 2	0.011
IRX5	iroquois homeobox 5	0.011
DGCR14	DiGeorge syndrome critical region gene 14	0.011
COL7A1	collagen, type VII, alpha 1	0.011
GATA2	GATA binding protein 2	0.011
FOXN4	forkhead box N4	0.011
HOXB9	homeobox B9	0.011
WFIKKN1	WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1	0.011
SOX2	SRY (sex determining region Y)-box 2	0.011
IHH	Indian hedgehog	0.010
WNT10A	wingless-type MMTV integration site family, member 10A	0.010	Human
TBX2	T-box 2	0.010
HOXD9	homeobox D9	0.010
ST8SIA2	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2	0.010
FZD8	frizzled homolog 8 (Drosophila)	0.010
DUSP2	dual specificity phosphatase 2	0.010
HOXA13	homeobox A13	0.010
AQP5	aquaporin 5	0.010
NPHP1	nephronophthisis 1 (juvenile)	0.010
HBEGF	heparin-binding EGF-like growth factor	0.010